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Search of human proteins with 156231067
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
(1140 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 2297 0.0
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 1158 0.0
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso... 1093 0.0
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 1092 0.0
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso... 1090 0.0
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso... 711 0.0
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 157 5e-38
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens] 150 7e-36
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 146 1e-34
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 145 2e-34
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 128 4e-29
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 124 7e-28
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 118 3e-26
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 118 4e-26
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 112 3e-24
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 111 4e-24
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 111 4e-24
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 108 4e-23
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 105 2e-22
gi|239755853 PREDICTED: TBC1 domain family, member 30 [Homo sapi... 98 4e-20
gi|239750365 PREDICTED: TBC1 domain family, member 30 [Homo sapi... 98 4e-20
gi|239744669 PREDICTED: TBC1 domain family, member 30 [Homo sapi... 98 4e-20
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 95 3e-19
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 95 3e-19
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 92 3e-18
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 78 4e-14
gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 73 1e-12
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 73 1e-12
gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 72 2e-12
gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 72 2e-12
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 2297 bits (5952), Expect = 0.0
Identities = 1140/1140 (100%), Positives = 1140/1140 (100%)
Query: 1 MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVA 60
MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVA
Sbjct: 1 MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVA 60
Query: 61 PFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKA 120
PFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKA
Sbjct: 61 PFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKA 120
Query: 121 LIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYL 180
LIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYL
Sbjct: 121 LIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYL 180
Query: 181 SINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEV 240
SINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEV
Sbjct: 181 SINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEV 240
Query: 241 FKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLH 300
FKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLH
Sbjct: 241 FKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLH 300
Query: 301 AVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLPH 360
AVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLPH
Sbjct: 301 AVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLPH 360
Query: 361 PIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTSM 420
PIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTSM
Sbjct: 361 PIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTSM 420
Query: 421 CSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLWN 480
CSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLWN
Sbjct: 421 CSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLWN 480
Query: 481 DHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESL 540
DHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESL
Sbjct: 481 DHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESL 540
Query: 541 GKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVL 600
GKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVL
Sbjct: 541 GKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVL 600
Query: 601 LLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSAL 660
LLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSAL
Sbjct: 601 LLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSAL 660
Query: 661 ASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQA 720
ASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQA
Sbjct: 661 ASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQA 720
Query: 721 LMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEKFGDQSVEQIE 780
LMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEKFGDQSVEQIE
Sbjct: 721 LMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEKFGDQSVEQIE 780
Query: 781 HLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMMSCYWEQPRPM 840
HLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMMSCYWEQPRPM
Sbjct: 781 HLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMMSCYWEQPRPM 840
Query: 841 ASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDDNMDQLIEFKA 900
ASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDDNMDQLIEFKA
Sbjct: 841 ASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDDNMDQLIEFKA 900
Query: 901 FVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLRNPLLSTSRPLVFGKPNGDA 960
FVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLRNPLLSTSRPLVFGKPNGDA
Sbjct: 901 FVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLRNPLLSTSRPLVFGKPNGDA 960
Query: 961 VDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATV 1020
VDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATV
Sbjct: 961 VDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATV 1020
Query: 1021 TTLLLQIGEVGQRGSSSGSCSQECGEELRASAPSPEDSVFADTGKTPQDSQAFPEAAERD 1080
TTLLLQIGEVGQRGSSSGSCSQECGEELRASAPSPEDSVFADTGKTPQDSQAFPEAAERD
Sbjct: 1021 TTLLLQIGEVGQRGSSSGSCSQECGEELRASAPSPEDSVFADTGKTPQDSQAFPEAAERD 1080
Query: 1081 WTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAKINQYNLKTFEMSHQSQSELKLSNL 1140
WTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAKINQYNLKTFEMSHQSQSELKLSNL
Sbjct: 1081 WTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAKINQYNLKTFEMSHQSQSELKLSNL 1140
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain) isoform
a [Homo sapiens]
Length = 1120
Score = 1158 bits (2995), Expect = 0.0
Identities = 614/1143 (53%), Positives = 795/1143 (69%), Gaps = 44/1143 (3%)
Query: 1 MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGE-GGGRLTGRLVGALDAVLDSNARV 59
MWLKPEEVLLKNALKLW+ ++S+ YF+LQRRRG+GE GGG LTG LVG LD+VLDS A+V
Sbjct: 1 MWLKPEEVLLKNALKLWLMERSNDYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKV 60
Query: 60 APFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVK 119
APFRIL Q P SQVY IACGA EEI +HWDWLEQN++ TLSVFD+ +DI +FV+GK++
Sbjct: 61 APFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIR 120
Query: 120 ALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLY 179
LIAEE A+ E++PEKFREAL+KFE F PE EKLVTYYSC WKGRVP QGWLY
Sbjct: 121 GLIAEEGKHCFAK-EDDPEKFREALLKFEKCFGLPEKEKLVTYYSCSYWKGRVPCQGWLY 179
Query: 180 LSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDE 239
LS N L FYSF LG E+KL++ W ++ KLE+TSNV LT++I + +Q + FSMFL++++
Sbjct: 180 LSTNFLSFYSFLLGSEIKLIISWDEVSKLEKTSNVILTESIHVCSQGENHYFSMFLHINQ 239
Query: 240 VFKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKL 299
+ +MEQLA+ +RRL D E FD DP L P QITKR LE RA +E F AFFRLP+ E L
Sbjct: 240 TYLLMEQLANYAIRRLFDKETFDNDPVLYNPLQITKRGLENRAHSEQFNAFFRLPKGESL 299
Query: 300 HAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLP 359
V +C LW PFS +T G+M S++YICFAS++ C +I+PLREV++I+K D+S
Sbjct: 300 KEVHECFLWVPFSHFNTHGKMCISENYICFASQDGNQCSVIIPLREVLAIDKTNDSS--- 356
Query: 360 HPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTS 419
+I+SI+ K AF+F E++D + LV L RL+ A+ H D L S S
Sbjct: 357 KSVIISIKGKTAFRFHEVKDFEQLVAKL--RLRCGAASTQYH------DISTELAISSES 408
Query: 420 MCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLW 479
F +++ ++SQ +E S ++ +AL+T F ++ +S+M +E++K W
Sbjct: 409 TEPSDNF-EVQSLTSQ------RECSKTVNTEALMTVFHPQNLETLNSKMLKEKMKEQSW 461
Query: 480 NDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEES 539
F E GR V MFRT+K R LV GIPE+LRG LW+LFS AV D+A++P YY +VE+S
Sbjct: 462 KILFAECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQS 521
Query: 540 LGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSV 599
LG C L TEEIERDL RSLPEHPAFQ++TGI+ALRRVLTAYA+RNPKIGYCQ+MNILTSV
Sbjct: 522 LGTCNLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSV 581
Query: 600 LLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSA 659
LLLY KEEEAFWLLVAVCERMLPDYFN R+IGA VDQ+VFEELI+ HLP+L EHM D++
Sbjct: 582 LLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRDHLPQLTEHMTDMTF 641
Query: 660 LASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQ 719
+SVSLSWFLTLF+S++P+ESAVNVVDCFFYDGIKAI QLGLA+L+ N + L + KDD +
Sbjct: 642 FSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAE 701
Query: 720 ALMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEKFGDQSVEQI 779
A+ L+RF D++ N+DSP P + SD++ + DI+DLIR+S EK+G+ E I
Sbjct: 702 AVTALNRFFDNVTNKDSPLPSNVQQGSNVSDEKTSHTRVDITDLIRESNEKYGNIRYEDI 761
Query: 780 EHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMMSCYWEQPRP 839
+R ++R+ V+Q E+TTKQNVLRVV +V + ++L+ELY +FK+E +SCYW P
Sbjct: 762 HSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKLSLQELDELYVIFKKELFLSCYWCLGCP 821
Query: 840 MASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDDNMDQLIEFK 899
+ HDPS PY EQY+ID +QF L+ L+SPW A+ + LA TFRLLD+N D LI FK
Sbjct: 822 VLKHHDPSLPYLEQYQIDCQQFRALYHLLSPWAHSANKDSLALWTFRLLDENSDCLINFK 881
Query: 900 AFVSCLDIMYNGEMNEKIKLLYRLHIPPALTE---NDRDSQSPLRNPLLSTSRPLVFGKP 956
F S +DIMYNG EK+KLL++LHIPPA TE D L L L KP
Sbjct: 882 EFSSAIDIMYNGSFTEKLKLLFKLHIPPAYTEVKSKDASKGDELSKEELLYFSQLHVSKP 941
Query: 957 NGD---------------AVDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLY 1001
+ +D Q L Q +L K K++ K+LP+M+Q +FIQF KTLY
Sbjct: 942 ANEKEAESAKHSPEKGKGKIDIQAYLSQWQDELFK-KEENIKDLPRMNQSQFIQFSKTLY 1000
Query: 1002 SMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSCSQECGEELRASAPSPEDSVFA 1061
++FHEDPEE LYQAIA VT+LLL++ EVG++ S S ++ + S E+ +
Sbjct: 1001 NLFHEDPEEESLYQAIAVVTSLLLRMEEVGRKLHSPTSSAKGFSGTVCGSGGPSEEKTGS 1060
Query: 1062 DTGKTPQDSQAFPEAAERDWTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAKINQYN 1121
K P + P+ W+ + E ILASLL E +LV FFEKP+D+K+KLENA+I+Q
Sbjct: 1061 HLEKDPCSFREEPQ-----WSFAFEQILASLLNEPALVRFFEKPIDVKAKLENARISQLR 1115
Query: 1122 LKT 1124
+T
Sbjct: 1116 SRT 1118
>gi|45597177 TBC1 domain family, member 9B (with GRAM domain) isoform
b [Homo sapiens]
Length = 1233
Score = 1093 bits (2827), Expect = 0.0
Identities = 575/1143 (50%), Positives = 763/1143 (66%), Gaps = 53/1143 (4%)
Query: 1 MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVA 60
MWL PEEVL+ NAL WVT++++ +F+LQRRRGHG GGG LTG LVG LD VLDS+ARVA
Sbjct: 1 MWLSPEEVLVANAL--WVTERANPFFVLQRRRGHGRGGG-LTGLLVGTLDVVLDSSARVA 57
Query: 61 PFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKA 120
P+RIL Q SQVY +ACG++ +EI +HW+WLE NLL TLS+FD+++DI +FVKGK+
Sbjct: 58 PYRILHQTQDSQVYWTVACGSSRKEITKHWEWLENNLLQTLSIFDSEEDITTFVKGKIHG 117
Query: 121 LIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYL 180
+IAEE + + +E+P KF+EA +K +F PE EKLV YYSC WKGRVPRQGWLYL
Sbjct: 118 IIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYYSCSYWKGRVPRQGWLYL 177
Query: 181 SINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEV 240
++NHLCFYSF LGKE+ LVV WVDI +LE+ + + ++IR+ T+++E FSMFLN+ E
Sbjct: 178 TVNHLCFYSFLLGKEVSLVVQWVDITRLEKNATLLFPESIRVDTRDQELFFSMFLNIGET 237
Query: 241 FKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQ------ITKRDLEARAQNEFFRAFFRLP 294
FK+MEQLA++ +R+LLD+E F D L P + KRDL+ARA+NE +RA FRLP
Sbjct: 238 FKLMEQLANLAMRQLLDSEGFLEDKALPRPIRPHRNISALKRDLDARAKNECYRATFRLP 297
Query: 295 RKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMED 354
R E+L C+LWTPF++ H G+MF S++YICFAS+E+ C +I+PLREV +EK +
Sbjct: 298 RDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKEEDACHLIIPLREVTIVEKADS 357
Query: 355 TSLLPHPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLV 414
+S+LP P+ +S +SK+ F F L+DRD LV+ + L++ + P S AS+V
Sbjct: 358 SSVLPSPLSISTKSKMTFLFANLKDRDFLVQRISDFLQKTPSKQP----GSIGSRKASVV 413
Query: 415 FHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDA---LVTAFQQ-SGSQSPDSRMS 470
ST + G + S + S + P A L+ FQ+ S + ++ +
Sbjct: 414 DPSTESSPAPQEGSEQPASPASPLSSRQSFCAQEAPTASQGLLKLFQKNSPMEDLGAKGA 473
Query: 471 REQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPG 530
+E++K W+ HF EYGR VCM+RT K R LV GIPESLRG LWLLFS A ++ +HPG
Sbjct: 474 KEKMKEESWHIHFFEYGRGVCMYRTAKTRALVLKGIPESLRGELWLLFSGAWNEMVTHPG 533
Query: 531 YYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYC 590
YY LVE+S GK L TEEIERDLHRS+PEHPAFQNE GIAALRRVLTAYA RNP IGYC
Sbjct: 534 YYAELVEKSTGKYSLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYC 593
Query: 591 QSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPEL 650
Q+MNI+TSVLLLY EEEAFWLLVA+CERMLPDY+N RV+GA VDQ +FEEL + LP+L
Sbjct: 594 QAMNIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNTRVVGALVDQGIFEELTRDFLPQL 653
Query: 651 AEHMNDLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAED 710
+E M DL ++S+SLSWFLTLFLS+MP ESAV +VDCFFY+GIK I Q+ LAVL+AN E
Sbjct: 654 SEKMQDLGVISSISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQ 713
Query: 711 LCSSKDDGQALMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEK 770
L D+G+A+ +L R+LD++ N+ S PP+ A S +P DI +L++ SYEK
Sbjct: 714 LLGCSDEGEAMTMLGRYLDNVVNKQSVSPPIPHLRALLSSSDDPPAEVDIFELLKVSYEK 773
Query: 771 FGDQSVEQIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMM 830
F E IE +R+K R++V+Q EDT K++V+R + ++ E+LE+LY +FK +H+
Sbjct: 774 FSSLRAEDIEQMRFKQRLKVIQSLEDTAKRSVVRAIPVDIGFSIEELEDLYMVFKAKHLA 833
Query: 831 SCYWEQPRPMASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDD 890
S YW R MA R DPS PY EQYRIDA QF LF ++PW CG+HT +LA R FRLLD+
Sbjct: 834 SQYWGCSRTMAGRRDPSLPYLEQYRIDASQFRELFASLTPWACGSHTPLLAGRMFRLLDE 893
Query: 891 NMDQLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALT--------------ENDRDS 936
N D LI FK FV+ + MY+G++ EK+K+LY+LH+PPAL+ D S
Sbjct: 894 NKDSLINFKEFVTGMSGMYHGDLTEKLKVLYKLHLPPALSPEEAESALEAAHYFTEDSSS 953
Query: 937 QSPLRNPLLSTSRPLVFGKPNG-DAVDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQ 995
+ L S G+ G + DY+ L+ K+ +K+ T K+LPKM+Q +FI+
Sbjct: 954 EEALPQEEQEGSGSEERGEEKGTSSPDYRHYLRMWAKEKEAQKE-TIKDLPKMNQEQFIE 1012
Query: 996 FCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQR-----GSSSGSCS--------- 1041
CKTLY+MF EDP E DLY AIATV +LLL+IGEVG++ G C+
Sbjct: 1013 LCKTLYNMFSEDPMEQDLYHAIATVASLLLRIGEVGKKFSARTGRKPRDCATEEDEPPAP 1072
Query: 1042 ---QECGEELR-ASAPSPEDSVFADT--GKTPQDSQAFPEAAERDWTVSLEHILASLLTE 1095
Q+ EL+ +A P+ DT GK PQ+SQ E + S +L+ T+
Sbjct: 1073 ELHQDAARELQPPAAGDPQAKAGGDTHLGKAPQESQVVVEGGSGEGQGSPSQLLSDDETK 1132
Query: 1096 QSL 1098
+
Sbjct: 1133 DDM 1135
Score = 47.0 bits (110), Expect = 1e-04
Identities = 21/39 (53%), Positives = 29/39 (74%)
Query: 1078 ERDWTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAK 1116
+ DW +S E ILAS+LTE LVNFFEK +D+ K+++ K
Sbjct: 1176 DTDWCISFEQILASILTESVLVNFFEKRVDIGLKIKDQK 1214
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 1092 bits (2823), Expect = 0.0
Identities = 560/1101 (50%), Positives = 752/1101 (68%), Gaps = 71/1101 (6%)
Query: 1 MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGH---GEGGGRLTGRLVGALDAVLDSNA 57
MW+ PEEVLL NAL W+T++++ YFILQRR+GH G GGG L G LVG LD VLDS+A
Sbjct: 1 MWVNPEEVLLANAL--WITERANPYFILQRRKGHAGDGGGGGGLAGLLVGTLDVVLDSSA 58
Query: 58 RVAPFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGK 117
RVAP+RIL Q P S VY IACG + +EI +HW+WLEQNLL TLS+F+N++DI +FV+GK
Sbjct: 59 RVAPYRILYQTPDSLVYWTIACGGSRKEITEHWEWLEQNLLQTLSIFENENDITTFVRGK 118
Query: 118 VKALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGW 177
++ +IAE +++++ EKF+EA+VKF F PE EKLV YYSC WKG+VPRQGW
Sbjct: 119 IQGIIAEYNKINDVKEDDDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGW 178
Query: 178 LYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNL 237
+YLSINHLCFYSF +G+E KLV+ WVDI +LE+ + + L D I+++T++ E FS+FLN+
Sbjct: 179 MYLSINHLCFYSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVSTRSSEHFFSVFLNI 238
Query: 238 DEVFKVMEQLADVTLRRLLDNEVFDLDPDL-----QEPSQIT--KRDLEARAQNEFFRAF 290
+E FK+MEQLA++ +R+LLDNE F+ D L + P +++ KRDL+ARA++E +RA
Sbjct: 239 NETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKRKSPKKVSALKRDLDARAKSERYRAL 298
Query: 291 FRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIE 350
FRLP+ EKL DC+LWTPF++ H G+MF S +YICF S+E+ C +I+PLREV +E
Sbjct: 299 FRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVE 358
Query: 351 KMEDTSLLPHPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYD------- 403
K + +S+LP P+ +S R+++ F F L+DRD LV+ + L+Q + ++ D
Sbjct: 359 KADSSSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSK--IYSDKEFAGSY 416
Query: 404 TSADDDM----ASLVFHSTSMC-SDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQ 458
S+DD++ +SLV S S G+ + + NS + + L+T ++
Sbjct: 417 NSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQ--------TLMTMYR 468
Query: 459 QSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLF 518
+ + + ++++E +K W HF EYG+ +CM+RTEK R+LV GIPES+RG LWLL
Sbjct: 469 RRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLL 528
Query: 519 SDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLT 578
S A+ + A+HPGYY +LVE+S+GK L TEEIERDLHRSLPEHPAFQNE GIAALRRVLT
Sbjct: 529 SGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLT 588
Query: 579 AYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSV 638
AYA RNP IGYCQ+MNI+TSVLLLY KEEEAFWLLVA+CERMLPDY+N RV+GA VDQ V
Sbjct: 589 AYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGV 648
Query: 639 FEELIKGHLPELAEHMNDLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQ 698
FEEL + ++P+L + M DL ++++SLSWFLTLFLS+MP ESAV VVDCFFY+GIK IFQ
Sbjct: 649 FEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQ 708
Query: 699 LGLAVLEANAEDLCSSKDDGQALMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVT 758
L LAVL+AN + L + KDDG+A+ +L R+LD + N+DS PP+ H+ SDD EPYP
Sbjct: 709 LALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVEPYPEV 768
Query: 759 DISDLIRDSYEKFGDQSVEQIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLE 818
DI LIR SYEKFG + IE +R+K R++V+Q EDTTK+NV+R ++ E S ++LE
Sbjct: 769 DIFRLIRTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELE 828
Query: 819 ELYDLFKREHMMSCYWEQPRPMASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTE 878
ELY LFK EH+ SCYW RHDPS PY EQYRID QF +F L+ PW CG H++
Sbjct: 829 ELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFALLFPWACGTHSD 888
Query: 879 ILAERTFRLLDDNMDQLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHI--PPALTENDRDS 936
+LA R F+LLD+N D LI F+ FVS L +G++ EK+KLLY++H+ P+ +++ DS
Sbjct: 889 VLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDS 948
Query: 937 QSPLRNPLLSTSRP---------------------LVFGKPN-GDAVDYQ--KQLKQMIK 972
P V KP+ G + Q + ++
Sbjct: 949 AFEATQYFFEDITPECTHVVGLDSRSKQGADDGFVTVSLKPDKGKRANSQENRNYLRLWT 1008
Query: 973 DLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQ 1032
K K K K+LPK++Q +FI+ CKT+Y+MF EDP E +LY A A VT+LLL+IGEVG+
Sbjct: 1009 PENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGK 1068
Query: 1033 -----------RGSSSGSCSQ 1042
G S SC Q
Sbjct: 1069 LFVAQPAKEGGSGGSGPSCHQ 1089
Score = 51.2 bits (121), Expect = 5e-06
Identities = 30/85 (35%), Positives = 50/85 (58%), Gaps = 9/85 (10%)
Query: 1056 EDSVFADTGKTPQDSQAFPEAA--ERDWTVSLEHILASLLTEQSLVNFFEKPLDMKSKLE 1113
ED+V +G Q + A P + +RDW ++ E LASLLTE +LV +F+KP+ M +++
Sbjct: 1185 EDTVLVRSG---QGTAALPRSTSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARIT 1241
Query: 1114 NAKINQYNLKTFEMSHQSQSELKLS 1138
+AK N++ S S+ ++S
Sbjct: 1242 SAK----NIRMMGKPLTSASDYEIS 1262
>gi|45597175 TBC1 domain family, member 9B (with GRAM domain) isoform
a [Homo sapiens]
Length = 1250
Score = 1090 bits (2818), Expect = 0.0
Identities = 577/1160 (49%), Positives = 767/1160 (66%), Gaps = 70/1160 (6%)
Query: 1 MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVA 60
MWL PEEVL+ NAL WVT++++ +F+LQRRRGHG GGG LTG LVG LD VLDS+ARVA
Sbjct: 1 MWLSPEEVLVANAL--WVTERANPFFVLQRRRGHGRGGG-LTGLLVGTLDVVLDSSARVA 57
Query: 61 PFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKA 120
P+RIL Q SQVY +ACG++ +EI +HW+WLE NLL TLS+FD+++DI +FVKGK+
Sbjct: 58 PYRILHQTQDSQVYWTVACGSSRKEITKHWEWLENNLLQTLSIFDSEEDITTFVKGKIHG 117
Query: 121 LIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYL 180
+IAEE + + +E+P KF+EA +K +F PE EKLV YYSC WKGRVPRQGWLYL
Sbjct: 118 IIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYYSCSYWKGRVPRQGWLYL 177
Query: 181 SINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEV 240
++NHLCFYSF LGKE+ LVV WVDI +LE+ + + ++IR+ T+++E FSMFLN+ E
Sbjct: 178 TVNHLCFYSFLLGKEVSLVVQWVDITRLEKNATLLFPESIRVDTRDQELFFSMFLNIGET 237
Query: 241 FKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQ------ITKRDLEARAQNEFFRAFFRLP 294
FK+MEQLA++ +R+LLD+E F D L P + KRDL+ARA+NE +RA FRLP
Sbjct: 238 FKLMEQLANLAMRQLLDSEGFLEDKALPRPIRPHRNISALKRDLDARAKNECYRATFRLP 297
Query: 295 RKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMED 354
R E+L C+LWTPF++ H G+MF S++YICFAS+E+ C +I+PLREV +EK +
Sbjct: 298 RDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKEEDACHLIIPLREVTIVEKADS 357
Query: 355 TSLLPHPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLV 414
+S+LP P+ +S +SK+ F F L+DRD LV+ + L++ + P S AS+V
Sbjct: 358 SSVLPSPLSISTKSKMTFLFANLKDRDFLVQRISDFLQKTPSKQP----GSIGSRKASVV 413
Query: 415 FHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDA---LVTAFQQ-SGSQSPDSRMS 470
ST + G + S + S + P A L+ FQ+ S + ++ +
Sbjct: 414 DPSTESSPAPQEGSEQPASPASPLSSRQSFCAQEAPTASQGLLKLFQKNSPMEDLGAKGA 473
Query: 471 REQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPG 530
+E++K W+ HF EYGR VCM+RT K R LV GIPESLRG LWLLFS A ++ +HPG
Sbjct: 474 KEKMKEESWHIHFFEYGRGVCMYRTAKTRALVLKGIPESLRGELWLLFSGAWNEMVTHPG 533
Query: 531 YYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYC 590
YY LVE+S GK L TEEIERDLHRS+PEHPAFQNE GIAALRRVLTAYA RNP IGYC
Sbjct: 534 YYAELVEKSTGKYSLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYC 593
Query: 591 QSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPEL 650
Q+MNI+TSVLLLY EEEAFWLLVA+CERMLPDY+N RV+GA VDQ +FEEL + LP+L
Sbjct: 594 QAMNIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNTRVVGALVDQGIFEELTRDFLPQL 653
Query: 651 AEHMNDLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAED 710
+E M DL ++S+SLSWFLTLFLS+MP ESAV +VDCFFY+GIK I Q+ LAVL+AN E
Sbjct: 654 SEKMQDLGVISSISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQ 713
Query: 711 LCSSKDDGQALMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEK 770
L D+G+A+ +L R+LD++ N+ S PP+ A S +P DI +L++ SYEK
Sbjct: 714 LLGCSDEGEAMTMLGRYLDNVVNKQSVSPPIPHLRALLSSSDDPPAEVDIFELLKVSYEK 773
Query: 771 FGDQSVEQIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMM 830
F E IE +R+K R++V+Q EDT K++V+R + ++ E+LE+LY +FK +H+
Sbjct: 774 FSSLRAEDIEQMRFKQRLKVIQSLEDTAKRSVVRAIPVDIGFSIEELEDLYMVFKAKHLA 833
Query: 831 SCYWEQPRPMASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDD 890
S YW R MA R DPS PY EQYRIDA QF LF ++PW CG+HT +LA R FRLLD+
Sbjct: 834 SQYWGCSRTMAGRRDPSLPYLEQYRIDASQFRELFASLTPWACGSHTPLLAGRMFRLLDE 893
Query: 891 NMDQLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPAL---------------TENDRD 935
N D LI FK FV+ + MY+G++ EK+K+LY+LH+PPAL TE+
Sbjct: 894 NKDSLINFKEFVTGMSGMYHGDLTEKLKVLYKLHLPPALSPEEAESALEAAHYFTEDSSS 953
Query: 936 SQSPLRNPL-------LSTSRPLVFGKPNG----------DAVDYQKQLKQMIKDLAKEK 978
SPL + L + P + +G + DY+ L+ K+ +K
Sbjct: 954 EASPLASDLDLFLPWEAQEALPQEEQEGSGSEERGEEKGTSSPDYRHYLRMWAKEKEAQK 1013
Query: 979 DKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQR----- 1033
+ T K+LPKM+Q +FI+ CKTLY+MF EDP E DLY AIATV +LLL+IGEVG++
Sbjct: 1014 E-TIKDLPKMNQEQFIELCKTLYNMFSEDPMEQDLYHAIATVASLLLRIGEVGKKFSART 1072
Query: 1034 GSSSGSCS------------QECGEELR-ASAPSPEDSVFADT--GKTPQDSQAFPEAAE 1078
G C+ Q+ EL+ +A P+ DT GK PQ+SQ E
Sbjct: 1073 GRKPRDCATEEDEPPAPELHQDAARELQPPAAGDPQAKAGGDTHLGKAPQESQVVVEGGS 1132
Query: 1079 RDWTVSLEHILASLLTEQSL 1098
+ S +L+ T+ +
Sbjct: 1133 GEGQGSPSQLLSDDETKDDM 1152
Score = 47.0 bits (110), Expect = 1e-04
Identities = 21/39 (53%), Positives = 29/39 (74%)
Query: 1078 ERDWTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAK 1116
+ DW +S E ILAS+LTE LVNFFEK +D+ K+++ K
Sbjct: 1193 DTDWCISFEQILASILTESVLVNFFEKRVDIGLKIKDQK 1231
>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
isoform b [Homo sapiens]
Length = 632
Score = 711 bits (1836), Expect = 0.0
Identities = 368/633 (58%), Positives = 464/633 (73%), Gaps = 20/633 (3%)
Query: 1 MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGE-GGGRLTGRLVGALDAVLDSNARV 59
MWLKPEEVLLKNALKLW+ ++S+ YF+LQRRRG+GE GGG LTG LVG LD+VLDS A+V
Sbjct: 1 MWLKPEEVLLKNALKLWLMERSNDYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKV 60
Query: 60 APFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVK 119
APFRIL Q P SQVY IACGA EEI +HWDWLEQN++ TLSVFD+ +DI +FV+GK++
Sbjct: 61 APFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIR 120
Query: 120 ALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLY 179
LIAEE A+ E++PEKFREAL+KFE F PE EKLVTYYSC WKGRVP QGWLY
Sbjct: 121 GLIAEEGKHCFAK-EDDPEKFREALLKFEKCFGLPEKEKLVTYYSCSYWKGRVPCQGWLY 179
Query: 180 LSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDE 239
LS N L FYSF LG E+KL++ W ++ KLE+TSNV LT++I + +Q + FSMFL++++
Sbjct: 180 LSTNFLSFYSFLLGSEIKLIISWDEVSKLEKTSNVILTESIHVCSQGENHYFSMFLHINQ 239
Query: 240 VFKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKL 299
+ +MEQLA+ +RRL D E FD DP L P QITKR LE RA +E F AFFRLP+ E L
Sbjct: 240 TYLLMEQLANYAIRRLFDKETFDNDPVLYNPLQITKRGLENRAHSEQFNAFFRLPKGESL 299
Query: 300 HAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLP 359
V +C LW PFS +T G+M S++YICFAS++ C +I+PLREV++I+K D+S
Sbjct: 300 KEVHECFLWVPFSHFNTHGKMCISENYICFASQDGNQCSVIIPLREVLAIDKTNDSS--- 356
Query: 360 HPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTS 419
+I+SI+ K AF+F E++D + LV L RL+ A+ H D L S S
Sbjct: 357 KSVIISIKGKTAFRFHEVKDFEQLVAKL--RLRCGAASTQYH------DISTELAISSES 408
Query: 420 MCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLW 479
F +++ ++SQ +E S ++ +AL+T F ++ +S+M +E++K W
Sbjct: 409 TEPSDNF-EVQSLTSQ------RECSKTVNTEALMTVFHPQNLETLNSKMLKEKMKEQSW 461
Query: 480 NDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEES 539
F E GR V MFRT+K R LV GIPE+LRG LW+LFS AV D+A++P YY +VE+S
Sbjct: 462 KILFAECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQS 521
Query: 540 LGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSV 599
LG C L TEEIERDL RSLPEHPAFQ++TGI+ALRRVLTAYA+RNPKIGYCQ+MNILTSV
Sbjct: 522 LGTCNLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSV 581
Query: 600 LLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGA 632
LLLY KEEEAFWLLVAVCERMLPDYFN R+IG+
Sbjct: 582 LLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGS 614
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 157 bits (397), Expect = 5e-38
Identities = 86/240 (35%), Positives = 139/240 (57%), Gaps = 4/240 (1%)
Query: 490 VCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEE 549
V + R+EK+R LV GIP +R +LW+ S A+ + Y +V+ S + ++
Sbjct: 99 VSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQ 158
Query: 550 IERDLHRSLPEHPAFQN--ETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEE 607
IE+DL R++P + F + G+ LRRVL A A P+IGYCQ ++ + LLL+ +EE
Sbjct: 159 IEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEE 218
Query: 608 EAFWLLVAVCERMLP-DYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLS-ALASVSL 665
+AFW++ A+ E +LP YF+ ++G Q DQ V LI +LP L + + + L+ ++L
Sbjct: 219 DAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITL 278
Query: 666 SWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQALMILS 725
WFLT F S++ ++ + + D FFY+G + +FQL L +L E+L S++ LS
Sbjct: 279 HWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLS 338
>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
Length = 336
Score = 150 bits (379), Expect = 7e-36
Identities = 78/221 (35%), Positives = 128/221 (57%), Gaps = 7/221 (3%)
Query: 494 RTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERD 553
R+ +++ V G+P R R+W++ S A + +PGYY L++ + + I D
Sbjct: 57 RSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNP--RLEDAIRTD 114
Query: 554 LHRSLPEHPAFQNETGIAALR---RVLTAYAHRNPKIGYCQSMNILTSVLLLYTK-EEEA 609
L+R+ P++ F+ T R VL AY H N +GYCQ MN + L+L T EEE+
Sbjct: 115 LNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEES 174
Query: 610 FWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASVSLS-WF 668
FWLL A+ R+LPDY++ ++G + DQ V EL++ LP + M L L ++ +S WF
Sbjct: 175 FWLLDALVGRILPDYYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWF 234
Query: 669 LTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAE 709
+ LF+ I+P+E+ + + DC F +G K IF++ L +++ + E
Sbjct: 235 ICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQE 275
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 146 bits (369), Expect = 1e-34
Identities = 89/270 (32%), Positives = 140/270 (51%), Gaps = 12/270 (4%)
Query: 479 WNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLA---SHPGYYGNL 535
W ++F M E ++ L+ GIP R ++W D T + PG++ L
Sbjct: 637 WENYFASTVNREMMCSPE-LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTL 695
Query: 536 VEESLGKCCLVTEEIERDLHRSLP--EHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSM 593
++++L K +++IE DL R+LP +H + GI LR VL A++ RNP IGYCQ +
Sbjct: 696 LQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGL 755
Query: 594 NILTSVLLLYTKEEEAFWLLVAVCERMLP-DYFNHRVIGAQVDQSVFEELIKGHLPELAE 652
N L +V LLY ++E+AFW LV + E +P DY+ ++G+QVDQ VF +L+ LP L
Sbjct: 756 NRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHG 815
Query: 653 HMNDLSA-LASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL 711
H ++ +WFL +F+ + + + D F Y+G K IF+ LA+ + E++
Sbjct: 816 HFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEI 875
Query: 712 CSSKDDGQALMILSRF----LDHIKNEDSP 737
+D L F LD D+P
Sbjct: 876 LKLQDSMSIFKYLRYFTRTILDARSGTDAP 905
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 145 bits (366), Expect = 2e-34
Identities = 85/256 (33%), Positives = 135/256 (52%), Gaps = 8/256 (3%)
Query: 479 WNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLA---SHPGYYGNL 535
W ++F M E ++ L+ GIP R ++W D T + PG++ L
Sbjct: 637 WENYFASTVNREMMCSPE-LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTL 695
Query: 536 VEESLGKCCLVTEEIERDLHRSLP--EHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSM 593
++++L K +++IE DL R+LP +H + GI LR VL A++ RNP IGYCQ +
Sbjct: 696 LQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGL 755
Query: 594 NILTSVLLLYTKEEEAFWLLVAVCERMLP-DYFNHRVIGAQVDQSVFEELIKGHLPELAE 652
N L +V LLY ++E+AFW LV + E +P DY+ ++G+QVDQ VF +L+ LP L
Sbjct: 756 NRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHG 815
Query: 653 HMNDLSA-LASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL 711
H ++ +WFL +F+ + + + D F Y+G K IF+ LA+ + E++
Sbjct: 816 HFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEI 875
Query: 712 CSSKDDGQALMILSRF 727
+D L F
Sbjct: 876 LKLQDSMSIFKYLRYF 891
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 128 bits (321), Expect = 4e-29
Identities = 83/254 (32%), Positives = 131/254 (51%), Gaps = 13/254 (5%)
Query: 461 GSQSPDSRMSREQIKI-----SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLW 515
GSQ + + +++ S W D + + + + +KIR GIP SLRGR W
Sbjct: 63 GSQGAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAK-KHKKIRLRCQKGIPPSLRGRAW 121
Query: 516 LLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAA--L 573
S L +PG + L + S G + + IERDLHR P H F + G L
Sbjct: 122 QYLSGGKVKLQQNPGKFDEL-DMSPGDPKWL-DVIERDLHRQFPFHEMFVSRGGHGQQDL 179
Query: 574 RRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQ 633
RVL AY P+ GYCQ+ + +VLL++ E+AFW LV +CE+ LP Y++ ++ Q
Sbjct: 180 FRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQ 239
Query: 634 VDQSVFEELIKGHLPELAEHMN--DLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYD 691
+D + L++ P +H++ + L ++ WF+ F +P S + V D FF +
Sbjct: 240 LDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMT-EWFMCAFSRTLPWSSVLRVWDMFFCE 298
Query: 692 GIKAIFQLGLAVLE 705
G+K IF++GL +L+
Sbjct: 299 GVKIIFRVGLVLLK 312
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 124 bits (310), Expect = 7e-28
Identities = 73/214 (34%), Positives = 109/214 (50%), Gaps = 5/214 (2%)
Query: 494 RTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERD 553
R +K++ GIP +LR R W L A + PG Y L E + E I RD
Sbjct: 81 RYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAEAPGDPQWM--ETIGRD 138
Query: 554 LHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFW 611
LHR P H F + G L +VL AY P+ GYCQ+ + +VLL++ EEAFW
Sbjct: 139 LHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFW 198
Query: 612 LLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASVSL-SWFLT 670
LV +CE LP Y+ + ++D VF L++ LP + +H+ + + L WFL
Sbjct: 199 CLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLC 258
Query: 671 LFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVL 704
LF +P + + V D F +G + +F++GL ++
Sbjct: 259 LFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLV 292
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 118 bits (296), Expect = 3e-26
Identities = 77/250 (30%), Positives = 125/250 (50%), Gaps = 6/250 (2%)
Query: 458 QQSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLL 517
Q SGS + + + W D F + + + R +K++ GIP SLR + W
Sbjct: 314 QYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSR-RFQKVKLRCRKGIPSSLRAKAWQY 372
Query: 518 FSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAA--LRR 575
S++ L +PG + L E + G + + IE+DLHR P H F G L R
Sbjct: 373 LSNSKELLEQNPGKFEEL-ERAPGDPKWL-DVIEKDLHRQFPFHEMFAARGGHGQQDLYR 430
Query: 576 VLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVD 635
+L AY P GYCQ+ + +VLL++ E+AFW LV +C++ LP Y++ + Q+D
Sbjct: 431 ILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLD 490
Query: 636 QSVFEELIKGHLPELAEHMNDLSALASVSLS-WFLTLFLSIMPLESAVNVVDCFFYDGIK 694
+F L++ P H+ + ++ WF+ +F +P S + V D FF +G+K
Sbjct: 491 GEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVK 550
Query: 695 AIFQLGLAVL 704
IF++ L +L
Sbjct: 551 IIFRVALVLL 560
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 118 bits (295), Expect = 4e-26
Identities = 70/203 (34%), Positives = 108/203 (53%), Gaps = 5/203 (2%)
Query: 497 KIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHR 556
++++L+ G+P R R+W PG Y L+ + +IE DL+R
Sbjct: 617 ELKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNR 676
Query: 557 SLPEHPAFQNETGIAA--LRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEE-AFWLL 613
+ P + F T LRRVL A++ +NP IGYCQ +N L ++ LL +EEE AFW L
Sbjct: 677 TFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCL 736
Query: 614 VAVCERMLP-DYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSA-LASVSLSWFLTL 671
VA+ E ++P DY+ + + +QVDQ V ++L+ LP L H+ L+ V+ +WFL +
Sbjct: 737 VAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVV 796
Query: 672 FLSIMPLESAVNVVDCFFYDGIK 694
F + + V D F Y+G K
Sbjct: 797 FADSLISNILLRVWDAFLYEGTK 819
>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
sapiens]
Length = 815
Score = 112 bits (279), Expect = 3e-24
Identities = 72/229 (31%), Positives = 119/229 (51%), Gaps = 9/229 (3%)
Query: 494 RTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERD 553
R + + LV G+PE+LR +W L + + A Y + ++S + I RD
Sbjct: 527 RPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESV-----ITRD 581
Query: 554 LHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFW 611
+HR+ P H F++ G +L ++ AY+ + IGYCQ + L +VLLL+ EE+AF
Sbjct: 582 IHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFC 641
Query: 612 LLVAVC-ERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASVSLS-WFL 669
+LV + + L D + + E L++ LP+L H +DL+ A + S WFL
Sbjct: 642 VLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFL 701
Query: 670 TLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDG 718
TLF + PL +++D +G+ IF + LA+L+ + EDL + +G
Sbjct: 702 TLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEG 750
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 111 bits (277), Expect = 4e-24
Identities = 94/332 (28%), Positives = 155/332 (46%), Gaps = 26/332 (7%)
Query: 403 DTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSE----ESEKEKSPLMHPDALVTAFQ 458
D+S+ + +++ TS + +LE+++ + E++ + M+ +
Sbjct: 9 DSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSS 68
Query: 459 QSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMF-----RTEKIRK-LVAMGIPESLRG 512
S S S +S L D ++ +GR + R EK+ K L+ GIP R
Sbjct: 69 LVSSSSASSNLSH------LEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRA 122
Query: 513 RLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAF--QNETGI 570
+W L A TD+ Y E L + I RD+ R+ PEH F Q+ G
Sbjct: 123 IVWQLLCSA-TDMPVKNQY-----SELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQ 176
Query: 571 AALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVC-ERMLPDYFNHRV 629
L V+ AY+ + ++GYCQ + +LL+ EEEAF + V + E L + F +
Sbjct: 177 EVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSM 236
Query: 630 IGAQVDQSVFEELIKGHLPELAEHMNDLSALASV-SLSWFLTLFLSIMPLESAVNVVDCF 688
+ FE +++ LP+L H S S+ + SWFLTLFL+ PL A V D F
Sbjct: 237 AELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIF 296
Query: 689 FYDGIKAIFQLGLAVLEANAEDLCSSKDDGQA 720
Y+G++ +F++GLA+L+ N +L +G +
Sbjct: 297 MYEGLEIVFRVGLALLQVNQAELMQLDMEGMS 328
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 111 bits (277), Expect = 4e-24
Identities = 94/332 (28%), Positives = 155/332 (46%), Gaps = 26/332 (7%)
Query: 403 DTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSE----ESEKEKSPLMHPDALVTAFQ 458
D+S+ + +++ TS + +LE+++ + E++ + M+ +
Sbjct: 9 DSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSS 68
Query: 459 QSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMF-----RTEKIRK-LVAMGIPESLRG 512
S S S +S L D ++ +GR + R EK+ K L+ GIP R
Sbjct: 69 LVSSSSASSNLSH------LEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRA 122
Query: 513 RLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAF--QNETGI 570
+W L A TD+ Y E L + I RD+ R+ PEH F Q+ G
Sbjct: 123 IVWQLLCSA-TDMPVKNQY-----SELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQ 176
Query: 571 AALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVC-ERMLPDYFNHRV 629
L V+ AY+ + ++GYCQ + +LL+ EEEAF + V + E L + F +
Sbjct: 177 EVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSM 236
Query: 630 IGAQVDQSVFEELIKGHLPELAEHMNDLSALASV-SLSWFLTLFLSIMPLESAVNVVDCF 688
+ FE +++ LP+L H S S+ + SWFLTLFL+ PL A V D F
Sbjct: 237 AELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIF 296
Query: 689 FYDGIKAIFQLGLAVLEANAEDLCSSKDDGQA 720
Y+G++ +F++GLA+L+ N +L +G +
Sbjct: 297 MYEGLEIVFRVGLALLQVNQAELMQLDMEGMS 328
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 108 bits (269), Expect = 4e-23
Identities = 73/235 (31%), Positives = 123/235 (52%), Gaps = 21/235 (8%)
Query: 494 RTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEE---- 549
R +++ LV G+PE+LRG +W L + + +LVE+ L+T+E
Sbjct: 555 RPKQLSSLVRNGVPEALRGEVWQLLAGCHNN--------DHLVEKYR---ILITKESPQD 603
Query: 550 --IERDLHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTK 605
I RD++R+ P H F++ G +L ++ AY+ + +IGYCQ + L +VLLL+
Sbjct: 604 SAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMP 663
Query: 606 EEEAFWLLVAVC-ERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASVS 664
EE+AF +LV + + L + F E L++ ++P+L H D+S A +
Sbjct: 664 EEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMY 723
Query: 665 LS-WFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDG 718
S WFLTLF + PL +++D +GI IF + L +L+ + +DL + +G
Sbjct: 724 ASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEG 778
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 105 bits (263), Expect = 2e-22
Identities = 80/271 (29%), Positives = 132/271 (48%), Gaps = 17/271 (6%)
Query: 458 QQSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMF------RTEKIRKLVAMGIPESLR 511
+ SGS S + + L D ++ +GR V + + +++++LV GIP R
Sbjct: 111 RNSGSSLVSSSSASSNLS-HLEEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFR 169
Query: 512 GRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIA 571
+W L A S P + E L + I RD+ R+ PEH F+ + +
Sbjct: 170 AIVWQLLCSA----QSMP--IKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLG 223
Query: 572 --ALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERM-LPDYFNHR 628
L V+ AY+ + ++GYCQ + +LL+ EEEAF + V + + L + F
Sbjct: 224 QEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPS 283
Query: 629 VIGAQVDQSVFEELIKGHLPELAEHMNDLSALASV-SLSWFLTLFLSIMPLESAVNVVDC 687
+ + FE +I+ HLPEL H S S+ + SWFLT+FL+ PL A + D
Sbjct: 284 MAELGLCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDI 343
Query: 688 FFYDGIKAIFQLGLAVLEANAEDLCSSKDDG 718
F +G++ +F++GLA+L+ N +L +G
Sbjct: 344 FMSEGLEIVFRVGLALLQMNQAELMQLDMEG 374
>gi|239755853 PREDICTED: TBC1 domain family, member 30 [Homo
sapiens]
Length = 761
Score = 98.2 bits (243), Expect = 4e-20
Identities = 67/250 (26%), Positives = 126/250 (50%), Gaps = 35/250 (14%)
Query: 502 VAMGIPESLRGRLWLLFSDAVTDLASHP---------GYYGNLVEESLGKCCLVTEEIER 552
++ GIP+ R ++WL +D + N ++S+G +I +
Sbjct: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGI------QIVK 136
Query: 553 DLHRS-LPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLL--LYTKEEEA 609
DLHR+ + + E L+RVL AYA N +GYCQ NIL +++L + E +A
Sbjct: 137 DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDA 196
Query: 610 FWLLVAVCERMLPD-YFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALAS------ 662
+++ + +++LP+ YF + + VD +VF +L++ LPEL++H++ L A+
Sbjct: 197 LKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGG 256
Query: 663 --------VSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL--C 712
++ WFLTLF + +P ++ + + D F++G + I ++ LA+ E + C
Sbjct: 257 YEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECC 316
Query: 713 SSKDDGQALM 722
+ D+ + M
Sbjct: 317 ETADEFYSTM 326
>gi|239750365 PREDICTED: TBC1 domain family, member 30 [Homo
sapiens]
Length = 761
Score = 98.2 bits (243), Expect = 4e-20
Identities = 67/250 (26%), Positives = 126/250 (50%), Gaps = 35/250 (14%)
Query: 502 VAMGIPESLRGRLWLLFSDAVTDLASHP---------GYYGNLVEESLGKCCLVTEEIER 552
++ GIP+ R ++WL +D + N ++S+G +I +
Sbjct: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGI------QIVK 136
Query: 553 DLHRS-LPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLL--LYTKEEEA 609
DLHR+ + + E L+RVL AYA N +GYCQ NIL +++L + E +A
Sbjct: 137 DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDA 196
Query: 610 FWLLVAVCERMLPD-YFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALAS------ 662
+++ + +++LP+ YF + + VD +VF +L++ LPEL++H++ L A+
Sbjct: 197 LKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGG 256
Query: 663 --------VSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL--C 712
++ WFLTLF + +P ++ + + D F++G + I ++ LA+ E + C
Sbjct: 257 YEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECC 316
Query: 713 SSKDDGQALM 722
+ D+ + M
Sbjct: 317 ETADEFYSTM 326
>gi|239744669 PREDICTED: TBC1 domain family, member 30 [Homo
sapiens]
Length = 761
Score = 98.2 bits (243), Expect = 4e-20
Identities = 67/250 (26%), Positives = 126/250 (50%), Gaps = 35/250 (14%)
Query: 502 VAMGIPESLRGRLWLLFSDAVTDLASHP---------GYYGNLVEESLGKCCLVTEEIER 552
++ GIP+ R ++WL +D + N ++S+G +I +
Sbjct: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGI------QIVK 136
Query: 553 DLHRS-LPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLL--LYTKEEEA 609
DLHR+ + + E L+RVL AYA N +GYCQ NIL +++L + E +A
Sbjct: 137 DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDA 196
Query: 610 FWLLVAVCERMLPD-YFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALAS------ 662
+++ + +++LP+ YF + + VD +VF +L++ LPEL++H++ L A+
Sbjct: 197 LKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGG 256
Query: 663 --------VSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL--C 712
++ WFLTLF + +P ++ + + D F++G + I ++ LA+ E + C
Sbjct: 257 YEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECC 316
Query: 713 SSKDDGQALM 722
+ D+ + M
Sbjct: 317 ETADEFYSTM 326
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 95.1 bits (235), Expect = 3e-19
Identities = 59/223 (26%), Positives = 108/223 (48%), Gaps = 7/223 (3%)
Query: 495 TEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDL 554
TEK + + GIP LRG +W L + Y L + G C +I+ D+
Sbjct: 90 TEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARG-CSPDIRQIDLDV 148
Query: 555 HRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWL 612
+R+ +H F++ G+ +L VL AY+ N ++GYCQ M+ +T++LL+Y EE+AFW
Sbjct: 149 NRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWA 208
Query: 613 LVAVC---ERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALAS-VSLSWF 668
LV + + + +F Q E+++ L +L +H++ S ++ WF
Sbjct: 209 LVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWF 268
Query: 669 LTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL 711
FL P + + D + ++G + + + +L+ + + L
Sbjct: 269 FQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHL 311
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 95.1 bits (235), Expect = 3e-19
Identities = 59/223 (26%), Positives = 108/223 (48%), Gaps = 7/223 (3%)
Query: 495 TEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDL 554
TEK + + GIP LRG +W L + Y L + G C +I+ D+
Sbjct: 107 TEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARG-CSPDIRQIDLDV 165
Query: 555 HRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWL 612
+R+ +H F++ G+ +L VL AY+ N ++GYCQ M+ +T++LL+Y EE+AFW
Sbjct: 166 NRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWA 225
Query: 613 LVAVC---ERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALAS-VSLSWF 668
LV + + + +F Q E+++ L +L +H++ S ++ WF
Sbjct: 226 LVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWF 285
Query: 669 LTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL 711
FL P + + D + ++G + + + +L+ + + L
Sbjct: 286 FQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHL 328
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 92.0 bits (227), Expect = 3e-18
Identities = 65/235 (27%), Positives = 106/235 (45%), Gaps = 7/235 (2%)
Query: 477 SLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNL- 535
++W GR+ F EK+ V G+P RG +W ++ P
Sbjct: 772 TVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKD 831
Query: 536 --VEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIA--ALRRVLTAYAHRNPKIGYCQ 591
+E L + I DL R+ P HP F + G +L +L AY+ + ++GYCQ
Sbjct: 832 VPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQ 891
Query: 592 SMNILTSVLLLYTKEEEAFWLLVAVCERM-LPDYFNHRVIGAQVDQSVFEELIKGHLPEL 650
++ + +LLL+ EEEAF +L + M L + +I Q+ L+ + +L
Sbjct: 892 GLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDL 951
Query: 651 AEHMNDLSALASV-SLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVL 704
H+ + S+ + WFLT+F S PL V D F G + IF++ L++L
Sbjct: 952 YNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLL 1006
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 78.2 bits (191), Expect = 4e-14
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 13/221 (5%)
Query: 496 EKIRKLVAMGIPESLRGRLWLLFS------DAVTDLASHPGYYGNLVEESLGKCCLVTEE 549
E I L+ G+P+S RG +W + + + P +E L +
Sbjct: 909 EDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNKQQPPDIS---YKELLKQLTAQQHA 965
Query: 550 IERDLHRSLPEHPAFQNETGIAALR--RVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEE 607
I DL R+ P HP F + G L +L AY+ + ++GYCQ ++ + VLLL+ EE
Sbjct: 966 ILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEE 1025
Query: 608 EAFWLL-VAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASV-SL 665
+AF +L + + + ++ Q+ L+ + +L H+ + S+ +
Sbjct: 1026 QAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAA 1085
Query: 666 SWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEA 706
WFLTLF S L V D F G + IF++ L++L +
Sbjct: 1086 PWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSS 1126
>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
Length = 549
Score = 73.2 bits (178), Expect = 1e-12
Identities = 57/232 (24%), Positives = 105/232 (45%), Gaps = 9/232 (3%)
Query: 505 GIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAF 564
G+P ++RG +W + + +PG Y +++E K + I+RD+ +L +H F
Sbjct: 101 GMPMNIRGPMWSVLLNTEEMKLKNPGRY-QIMKEKGKKSSEHIQRIDRDVSGTLRKHIFF 159
Query: 565 QNETGIAA--LRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAV--CERM 620
++ G L +L AY NP++GYC+ ++ + ++ LLY EE+AFW LV + ER
Sbjct: 160 RDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERH 219
Query: 621 LPDYFNHRVIGAQVD--QSVFEELIKGHLPELAEHMNDLSALASVS-LSWFLTLFLSIMP 677
F H G V Q E ++ P+ H + S L + + + +
Sbjct: 220 SLQGF-HSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGIS 278
Query: 678 LESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQALMILSRFLD 729
L + + D + +G +A+ + + + L + G +RF+D
Sbjct: 279 LGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVD 330
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 73.2 bits (178), Expect = 1e-12
Identities = 63/269 (23%), Positives = 117/269 (43%), Gaps = 12/269 (4%)
Query: 468 RMSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLAS 527
++ RE + S W + E+ + K+ V GIP ++RG +W + +
Sbjct: 66 KIRREMTRTSKWMEMLGEWETYK---HSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIKLK 122
Query: 528 HPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAA--LRRVLTAYAHRNP 585
+PG Y +++E + I+ D+ +L H F++ G L +L AY+ NP
Sbjct: 123 NPGRY-QIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNP 181
Query: 586 KIGYCQSMNILTSVLLLYTKEEEAFWLLVAVC---ERMLPDYFNHRVIGAQVDQSVFEEL 642
++GYC+ ++ +T++ LLY EE+AFW LV + LP + + Q Q E +
Sbjct: 182 EVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHV 241
Query: 643 IKGHLPELAEHMNDLSALAS--VSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLG 700
+ P+ H D L SL L + + L + + D + +G + + +
Sbjct: 242 VPKSQPKTMWH-QDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPIT 300
Query: 701 LAVLEANAEDLCSSKDDGQALMILSRFLD 729
L+ + L + G + ++F D
Sbjct: 301 SIALKVQQKRLMKTSRCGLWARLRNQFFD 329
>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
Length = 549
Score = 72.4 bits (176), Expect = 2e-12
Identities = 56/232 (24%), Positives = 105/232 (45%), Gaps = 9/232 (3%)
Query: 505 GIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAF 564
G+P ++RG +W + + +PG Y +++E + + I+RD+ +L +H F
Sbjct: 101 GMPMNIRGPMWSVLLNIEEMKLKNPGRY-QIMKEKGKRSSEHIQRIDRDISGTLRKHMFF 159
Query: 565 QNETGIAA--LRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAV--CERM 620
++ G L +L AY NP++GYC+ ++ + ++ LLY EE+AFW LV + ER
Sbjct: 160 RDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERH 219
Query: 621 LPDYFNHRVIGAQVD--QSVFEELIKGHLPELAEHMNDLSALASVS-LSWFLTLFLSIMP 677
F H G V Q E ++ P+ H + S L + + + +
Sbjct: 220 SLQGF-HSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGIS 278
Query: 678 LESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQALMILSRFLD 729
L + + D + +G +A+ + + + L + G +RF+D
Sbjct: 279 LGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVD 330
>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
Length = 549
Score = 72.4 bits (176), Expect = 2e-12
Identities = 56/232 (24%), Positives = 105/232 (45%), Gaps = 9/232 (3%)
Query: 505 GIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAF 564
G+P ++RG +W + + +PG Y +++E + + I+RD+ +L +H F
Sbjct: 101 GMPMNIRGPMWSVLLNIEEMKLKNPGRY-QIMKEKGKRSSEHIQRIDRDISGTLRKHMFF 159
Query: 565 QNETGIAA--LRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAV--CERM 620
++ G L +L AY NP++GYC+ ++ + ++ LLY EE+AFW LV + ER
Sbjct: 160 RDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERH 219
Query: 621 LPDYFNHRVIGAQVD--QSVFEELIKGHLPELAEHMNDLSALASVS-LSWFLTLFLSIMP 677
F H G V Q E ++ P+ H + S L + + + +
Sbjct: 220 SLQGF-HSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGIS 278
Query: 678 LESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQALMILSRFLD 729
L + + D + +G +A+ + + + L + G +RF+D
Sbjct: 279 LGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVD 330
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,732,586
Number of Sequences: 37866
Number of extensions: 1916314
Number of successful extensions: 6191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 5961
Number of HSP's gapped (non-prelim): 140
length of query: 1140
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1027
effective length of database: 13,968,660
effective search space: 14345813820
effective search space used: 14345813820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.