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Search of human proteins with 156142178
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156142178 coiled-coil domain containing 59 [Homo sapiens]
(241 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156142178 coiled-coil domain containing 59 [Homo sapiens] 490 e-139
gi|148746195 trichohyalin [Homo sapiens] 51 1e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 47 1e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 47 1e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 47 1e-05
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 47 2e-05
gi|219803769 trichoplein [Homo sapiens] 44 1e-04
gi|14150056 trichoplein [Homo sapiens] 44 1e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 43 3e-04
gi|34878777 ring finger protein 20 [Homo sapiens] 43 3e-04
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 42 4e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 42 5e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 42 5e-04
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 42 6e-04
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 42 6e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 41 8e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 41 8e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 41 8e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 41 8e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 41 8e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 41 8e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 41 8e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 41 8e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 41 0.001
gi|168229156 NFKB activating protein [Homo sapiens] 41 0.001
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 41 0.001
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 41 0.001
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa... 40 0.001
gi|157785548 PAS domain containing 1 [Homo sapiens] 40 0.001
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s... 40 0.001
>gi|156142178 coiled-coil domain containing 59 [Homo sapiens]
Length = 241
Score = 490 bits (1262), Expect = e-139
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MAPVRRSAKWRPGGIEARGEGVSTVGYRNKNVRQKTWRPNHPQAFVGSVREGQGFAFRRK 60
MAPVRRSAKWRPGGIEARGEGVSTVGYRNKNVRQKTWRPNHPQAFVGSVREGQGFAFRRK
Sbjct: 1 MAPVRRSAKWRPGGIEARGEGVSTVGYRNKNVRQKTWRPNHPQAFVGSVREGQGFAFRRK 60
Query: 61 LKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVH 120
LKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVH
Sbjct: 61 LKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVH 120
Query: 121 QPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQ 180
QPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQ
Sbjct: 121 QPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQ 180
Query: 181 AKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
AKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK
Sbjct: 181 AKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
Query: 241 C 241
C
Sbjct: 241 C 241
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/177 (24%), Positives = 89/177 (50%), Gaps = 18/177 (10%)
Query: 57 FRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKH----LYLAEEERHRKQARKVD 112
+R+K ++QQ ++LLR+E++ + E + R + L+ L E E R+Q +
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
Query: 113 HPLSEQVHQPLLEEQCSIDEPLF------EDQCSFDQP--QPEEQCIKTVNSFTIPKKNK 164
+ E++ Q EEQ +EP E QC ++ Q EEQ ++ K+ +
Sbjct: 1080 YRKEEELQQE--EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE----KRRR 1133
Query: 165 KKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKK 221
++ Q +EE Q + ++ +++ +RR+QE E R+ ++ + E ++L ++ +K
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK 1190
Score = 48.5 bits (114), Expect = 5e-06
Identities = 50/206 (24%), Positives = 100/206 (48%), Gaps = 27/206 (13%)
Query: 57 FRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHL--YLAEEERHRKQAR----- 109
+R + ++QQ ++LLR+E++ + E + R D L+ L EER +++ +
Sbjct: 990 YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Query: 110 -KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQ--PQPEEQCIKTVNSFTIPKKNKKK 166
+ + L ++ Q L EE+ + E Q ++ Q EEQ ++ P+K +++
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE-----PEKRRRQ 1104
Query: 167 TSNQKAQEEYEQIQAKRAAKKQEFE-RRKQEREEAQRQYKKKKMEVFKILNKKTKK---- 221
++ +EE E Q + ++E E RR+QE E R+ ++ + E ++L ++ +K
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 222 -------GQPNLNVQMEYLLQKIQEK 240
+ L + E LL++ QEK
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEK 1190
Score = 48.1 bits (113), Expect = 7e-06
Identities = 36/154 (23%), Positives = 76/154 (49%), Gaps = 22/154 (14%)
Query: 57 FRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHL--YLAEEERHRKQARKVDHP 114
+R++ ++QQ ++LLR+E + + E + R + L+ L EER +++ ++++
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
E+ EEQ +EP + ++ EE+ ++ QE
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ--------------------QE 1179
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKK 208
E + ++ ++ ++QE ER+ +E EE QRQ +K++
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Score = 47.8 bits (112), Expect = 9e-06
Identities = 42/162 (25%), Positives = 82/162 (50%), Gaps = 18/162 (11%)
Query: 57 FRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKH----LYLAEEERHRKQAR--- 109
+R + ++QQ ++LL +E++ + E + R + L+ L E E+ R+Q R
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109
Query: 110 -KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQP--QPEEQCIKTVNSFTIPKKNKKK 166
+ + L ++ Q L EE+ E Q ++ Q EEQ ++ P+K +++
Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE-----PEKRRRQ 1164
Query: 167 TSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKK 208
++ +EE E Q + ++E E+R+QERE RQY++++
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERE---RQYREEE 1203
Score = 46.6 bits (109), Expect = 2e-05
Identities = 50/208 (24%), Positives = 103/208 (49%), Gaps = 17/208 (8%)
Query: 50 REGQGFAFRRKLKIQQSYKKLLR--KEKKAQTSLESQF-TDRYPDNLKHLYLAEE-ERHR 105
R+ Q +R + ++QQ ++LLR +EK+ + E Q+ D+ + L EE E+ R
Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Query: 106 KQAR----KVDHPLSEQVHQPLLEEQCSIDEPLFEDQC--SFDQPQPEEQCIKTV-NSFT 158
+Q R + + L ++ Q L EE+ +E Q + Q EEQ ++
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042
Query: 159 IPKKNKKKTSNQKAQEEYEQI--QAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ ++ ++ Q+E EQ+ + + ++QE ER+ ++ EE Q++ ++ E +
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 217 KKTKKGQ----PNLNVQMEYLLQKIQEK 240
++ ++ Q L + E LL++ +EK
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREK 1130
Score = 45.8 bits (107), Expect = 3e-05
Identities = 44/206 (21%), Positives = 95/206 (46%), Gaps = 39/206 (18%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSE 117
RR+ + ++ + L +E++ Q +Q D L+ ++ER R Q ++ D
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE----DQERRRSQEQRRDQKWRW 876
Query: 118 QVHQ------------PLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK 165
Q+ + P L+EQ ++ L +++ ++ Q EE+ K+ ++
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE--EEELQREER----------EKRRRQ 924
Query: 166 KTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKK---- 221
+ Q +EE Q + ++ +++ +RR+QERE R+ KK + + ++L ++ +K
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 222 -------GQPNLNVQMEYLLQKIQEK 240
+ L + E LL++ +EK
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREK 1010
Score = 41.2 bits (95), Expect = 8e-04
Identities = 45/180 (25%), Positives = 78/180 (43%), Gaps = 38/180 (21%)
Query: 59 RKLKIQQSYKK---LLRKEKKAQTSLESQFTDRYPDNLKH--LYLAEEERHRKQARKVDH 113
++LK +Q ++ L R+E++ Q L+ + +R LK + E+E R+Q K +
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 114 PLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQ 173
P E+ Q L E+ E + Q +Q + EQ +K ++ K+ ++ +
Sbjct: 625 PEEERRQQLLKSEE---QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
Query: 174 E----EYEQIQAKRAAK--------------------------KQEFERRKQEREEAQRQ 203
E E EQ QA+ K KQE +RR+QE+EE +R+
Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
Score = 40.8 bits (94), Expect = 0.001
Identities = 48/214 (22%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 28 RNKNVRQKTW--RPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQF 85
R++ ++ W R H RE Q A RR K Q+ K+LLR+E++ + Q
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE-KQLLREEREEKR--RRQE 1333
Query: 86 TDR-YPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
TDR + + + L EE+ R+Q R E HQ EQ E++ +
Sbjct: 1334 TDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ----EQ---GRKFLEEEQRLRRQ 1386
Query: 145 QPEEQCIKTVNSFTIPKKNK--KKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQR 202
+ E + +K ++ + ++ ++K +EE +Q+ + +K E ++ R+E +R
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 203 QYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQK 236
++ +++ ++ + ++K ++ + L + E L +
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/150 (20%), Positives = 74/150 (49%), Gaps = 15/150 (10%)
Query: 72 RKEKKAQTSLESQFTDRYPDN--LKHLYLAE------EERHRKQARKVDHPLSEQVHQPL 123
R E++ S + T+ +PD L+ L E EE+ +++ + D E+ +
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEW 246
Query: 124 LEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKR 183
+ + + + E++ ++PQ + + + + K +++ ++ +EE +Q + +R
Sbjct: 247 RKRETVLRKE--EEKLQEEEPQRQRELQEEEEQ--LRKLERQELRRERQEEEQQQQRLRR 302
Query: 184 AA---KKQEFERRKQEREEAQRQYKKKKME 210
+KQE ERR+Q+ E ++Q ++++ E
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQE 332
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/171 (18%), Positives = 80/171 (46%), Gaps = 2/171 (1%)
Query: 72 RKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSID 131
R++++ + E + +R+ + ++ER +Q R+ EQ + EE+
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 132 EPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFE 191
E Q +Q + EQ +K + ++ +++ ++ +E +Q+ + ++Q+
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 192 RRKQEREEAQRQYKK--KKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+R+QE QR ++ +++E + ++ K+ +P + + L + QE+
Sbjct: 591 KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Score = 40.0 bits (92), Expect = 0.002
Identities = 45/173 (26%), Positives = 81/173 (46%), Gaps = 27/173 (15%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSE 117
R L + + ++ LRKE++ E + L E E+ R+Q ++ + E
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEE-----------LQREEREKRRRQEQERQYREEE 934
Query: 118 QVHQP----LLEEQCSIDEPLFEDQCSFDQP--QPEEQCIKTVNSFTIPKKNKKKTSNQK 171
Q+ Q L EE+ E Q D+ Q EEQ + P+K +++ +K
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE-----PEKRRRQEREKK 989
Query: 172 AQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKK---KMEVFKILNKKTKK 221
+EE E Q + ++E E+R+ R+E +RQY+KK + E ++L ++ +K
Sbjct: 990 YREEEELQQEEEQLLREEREKRR--RQEWERQYRKKDELQQEEEQLLREEREK 1040
Score = 38.1 bits (87), Expect = 0.007
Identities = 31/158 (19%), Positives = 74/158 (46%), Gaps = 11/158 (6%)
Query: 63 IQQSYKKLLR--KEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVH 120
+Q+ ++L R +EK+ + E Q+ + + L EER +++ ++ + +
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 121 QPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQ---------K 171
EEQ +EP + ++ EE+ ++ + ++ +K+ + +
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 172 AQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKM 209
Q+E EQ+ + K++ ER +Q REE + Q +++++
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL 1063
Score = 38.1 bits (87), Expect = 0.007
Identities = 44/201 (21%), Positives = 89/201 (44%), Gaps = 18/201 (8%)
Query: 58 RRKLKIQQSYKKLLRKEK----KAQTSLESQFTDR-YPDNLKHLYLAEEERHRKQARKVD 112
+ +L+ Q+ Y+K+L +E+ + + L Q DR + + + EE++ R Q
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Query: 113 HPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQ----------CIKTVNSFTIPKK 162
EQ+ Q E+Q + + + +Q Q EEQ + F +K
Sbjct: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
Query: 163 NKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKG 222
++++ +EE ++ Q + ++E RR+Q+ E+ RQ + K + K + + G
Sbjct: 1857 SRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPG 1916
Query: 223 Q---PNLNVQMEYLLQKIQEK 240
++ V+ L + IQE+
Sbjct: 1917 THQFASVPVRSSPLYEYIQEQ 1937
Score = 37.0 bits (84), Expect = 0.015
Identities = 37/178 (20%), Positives = 86/178 (48%), Gaps = 17/178 (9%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSE 117
RR+ +++ +K L +E++ Q L+ + +R LK EEER +++ ++ E
Sbjct: 545 RREQLLKREEEKRLEQERREQR-LKREQEERRDQLLKR----EEERRQQRLKREQE---E 596
Query: 118 QVHQPLLEEQCSI--DEPLFEDQCSFDQPQPE--EQCIKTVNSFTIPKKNKKKTSNQKAQ 173
++ Q L E+ E E + ++P+ E +Q +K+ ++ +++ ++ Q
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE-----QEERRQQQLRREQ 651
Query: 174 EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQME 231
+E + + KR +++ E+R + E +R+ ++ E + ++ K P Q+E
Sbjct: 652 QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709
Score = 36.6 bits (83), Expect = 0.020
Identities = 35/159 (22%), Positives = 77/159 (48%), Gaps = 14/159 (8%)
Query: 58 RRKLKIQQSYKKLLRK--EKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPL 115
RR+ + ++ ++L R+ E++ Q Q +R L+ EEER +Q R+
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ--EEERREQQLRREQQLR 384
Query: 116 SEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEE 175
EQ L EQ + E Q +Q EQ ++ ++ +++ ++ +++
Sbjct: 385 REQ---QLRREQ----QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Query: 176 YEQIQAKRAAKKQEFERR---KQEREEAQRQYKKKKMEV 211
+EQ + ++ K+++ ERR K+E E + + +++K ++
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Score = 36.6 bits (83), Expect = 0.020
Identities = 32/142 (22%), Positives = 65/142 (45%), Gaps = 5/142 (3%)
Query: 64 QQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPL 123
+Q K +E++ Q L + +R LK EEE +Q K +H E+ Q L
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKR---EEEEERLEQRLKREHE-EERREQEL 685
Query: 124 LEEQCSIDEPLFEDQCSFDQPQPEEQC-IKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAK 182
EE+ + + Q Q E + + ++ P+K + + Q+ +E+ + +++
Sbjct: 686 AEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 183 RAAKKQEFERRKQEREEAQRQY 204
+++E R+Q+ EE +R +
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDF 767
Score = 36.2 bits (82), Expect = 0.026
Identities = 31/137 (22%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Query: 100 EEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTI 159
E+ER ++Q ++ + L EE+ + E Q +Q + EQ +K
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE--E 525
Query: 160 PKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKT 219
+ ++ S Q+ + E E+ + ++ K++E +R +QER E QR ++++ ++L ++
Sbjct: 526 ERLQQRLRSEQQLRREQEE-RREQLLKREEEKRLEQERRE-QRLKREQEERRDQLLKREE 583
Query: 220 KKGQPNLNVQMEYLLQK 236
++ Q L + E L++
Sbjct: 584 ERRQQRLKREQEERLEQ 600
Score = 35.8 bits (81), Expect = 0.034
Identities = 34/153 (22%), Positives = 79/153 (51%), Gaps = 11/153 (7%)
Query: 72 RKEKKAQTSLESQFTDRYPD-NLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSI 130
R+ ++ + +SQ DR +L+HL ++ER R+Q R+ +Q + EE+
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR----RWQQRDRHFPEEEQLE 1300
Query: 131 DEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAK--RAAKKQ 188
E E + + Q E+Q ++ +K +++ +++K +EE + +Q + + ++Q
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREERE----EKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 189 EFERRKQEREEAQRQYKKKKMEVFKILNKKTKK 221
E +R+ +E E ++ +K +E + L ++ ++
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Score = 35.8 bits (81), Expect = 0.034
Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 26/184 (14%)
Query: 59 RKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEE---ERHRKQARKVDHPL 115
R K ++ ++L R+E+ + E Q R K L ++ ERHRK R+ + L
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK-FREEEQLL 1470
Query: 116 SEQVHQPL---------LEEQCSID----EPLFEDQCSFDQPQPEEQCIKTVNSFTIPKK 162
E+ Q L LEE+ + + F +Q +PE + ++ ++
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ-ELRSQEPERKFLEEEQQLHRQQR 1529
Query: 163 NKKKTSNQ---KAQEEYEQIQAKRAAKKQEFERRKQEREEAQ--RQYKKKKMEVFKILNK 217
+K + + QE +Q + R K +E E+ +QEREE Q RQ + +K F++ +
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK---FRLEEQ 1586
Query: 218 KTKK 221
K ++
Sbjct: 1587 KVRR 1590
Score = 34.7 bits (78), Expect = 0.076
Identities = 31/157 (19%), Positives = 69/157 (43%), Gaps = 5/157 (3%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHR--KQARKVDHPL 115
R+ Q+ +K RK + E + + P + L EE+ + +Q + +
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE 292
Query: 116 SEQVHQPLLEEQC---SIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKA 172
EQ Q L EQ +E E Q + Q + + + ++ +++ Q
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352
Query: 173 QEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKM 209
+E+ E+ + ++ ++QE ERR+Q+ Q+ +++++
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Score = 34.3 bits (77), Expect = 0.099
Identities = 32/188 (17%), Positives = 92/188 (48%), Gaps = 20/188 (10%)
Query: 59 RKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQ 118
RK ++++ + +R++++ + +E + R + + L + + R+ + + +Q
Sbjct: 1579 RKFRLEE---QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 119 VHQP-----LLEEQCSIDEPLFEDQCSFDQPQP---EEQCIKTVNSFTIPKKNKKKTSNQ 170
+H+ LEE+ + E Q D+ + EEQ ++ ++ +++ ++
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE----QQLRRQERDR 1691
Query: 171 KAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQM 230
K +EE +Q++ + +K E ++ R+E +R++++++ L ++T++ Q +
Sbjct: 1692 KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ-----LRQETEQEQLRRQERY 1746
Query: 231 EYLLQKIQ 238
+L++ Q
Sbjct: 1747 RKILEEEQ 1754
Score = 33.5 bits (75), Expect = 0.17
Identities = 33/153 (21%), Positives = 73/153 (47%), Gaps = 21/153 (13%)
Query: 100 EEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTI 159
EE++ R + R D L E+ Q +++ + L E + ++ + EQ + +
Sbjct: 116 EEDQRRFEPR--DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 160 PKKNKKKTSNQKAQEEYEQIQAKRAAKKQEF------------ERRKQEREEAQRQYKKK 207
++ ++ ++ + E EQ+Q+ + + +EF E R++ REE Q+Q +++
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 208 KMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+ VF+ +K + + E +L+K +EK
Sbjct: 234 QDRVFQEEEEKEWR-------KRETVLRKEEEK 259
Score = 33.1 bits (74), Expect = 0.22
Identities = 22/143 (15%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 72 RKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSID 131
++E++ Q + +R L+ E+ ++ + + +++ Q E++ +
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 132 EPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKR----AAKK 187
+ DQ + + +Q +K + ++ K++ + QEE + + KR ++
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 188 QEFERRKQEREEAQRQYKKKKME 210
Q+ + +++ E Q+Q ++++ E
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQE 653
Score = 32.7 bits (73), Expect = 0.29
Identities = 29/149 (19%), Positives = 70/149 (46%), Gaps = 13/149 (8%)
Query: 64 QQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPL 123
+Q ++ +E++ Q Q +R L+ E++ R+Q + + L + Q
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRR----EQQLRREQQLRREQQLRRE-QQLR 402
Query: 124 LEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQ----I 179
E+Q ++ L +Q Q + E+Q + +K++++ Q+ + E E+ +
Sbjct: 403 REQQLRREQQLRREQ----QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 180 QAKRAAKKQEFERRKQEREEAQRQYKKKK 208
+ + ++ E ERRKQ+ + Q + ++++
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRER 487
Score = 31.6 bits (70), Expect = 0.64
Identities = 24/145 (16%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
Query: 68 KKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQV--HQPLLE 125
++LL +K + + Q +R + E + RK + L E+ Q L+
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 126 EQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAA 185
E+ L + ++ + E+Q + + +K +++ Q+ + +Q + ++
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 186 KKQEFERRKQEREEAQRQYKKKKME 210
+++E + R+++ E ++Q ++++ E
Sbjct: 333 ERREQQLRREQEERREQQLRREQEE 357
Score = 31.2 bits (69), Expect = 0.84
Identities = 33/196 (16%), Positives = 90/196 (45%), Gaps = 32/196 (16%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSE 117
RR+ K Q+ ++L E++++ + DR + + L+ +E ++ R+ + E
Sbjct: 136 RRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD-EELWRQRQEWQEREERRAEE---E 191
Query: 118 QVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQ---- 173
Q+ + C E + P+E+ ++ + +K +++ Q+ +
Sbjct: 192 QL------QSCKGHET---------EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
Query: 174 ----EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKK-----KKMEVFKILNKKTKKGQP 224
EE ++ + + ++E E+ ++E + QR+ ++ +K+E ++ ++ ++ Q
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 225 NLNVQMEYLLQKIQEK 240
++ E L++ QE+
Sbjct: 297 QQRLRREQQLRRKQEE 312
Score = 30.4 bits (67), Expect = 1.4
Identities = 41/190 (21%), Positives = 87/190 (45%), Gaps = 25/190 (13%)
Query: 64 QQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQAR----KVDHPLSEQV 119
Q+ ++K +E+ Q E Q + D +L EE++ R+Q R + S++
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRK---FLEEEQQLRRQERDRKFREQELRSQEP 1513
Query: 120 HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQI 179
+ LEE+ + L Q Q E+Q + ++ + + + +E+ Q
Sbjct: 1514 ERKFLEEE----QQLHRQQRQRKFLQEEQQLRRQERG---QQRRQDRDRKFREEEQLRQE 1566
Query: 180 QAKRAAKKQEFER--RKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQM------- 230
+ ++ +QE +R R +E++ +++ ++K ME + L + ++GQ L +
Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR--QEGQQQLRQERDRKFRED 1624
Query: 231 EYLLQKIQEK 240
E LLQ+ +E+
Sbjct: 1625 EQLLQEREEQ 1634
Score = 29.3 bits (64), Expect = 3.2
Identities = 33/178 (18%), Positives = 79/178 (44%), Gaps = 18/178 (10%)
Query: 62 KIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKV----DHPLSE 117
+++Q + R++++ E Q R + K +L EE + R+Q R+ D
Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQQLHRQERDRK--FLEEEPQLRRQEREQQLRHDRDRKF 1669
Query: 118 QVHQPLLEE-------QCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQ 170
+ + LL+E + D E++ + + E + ++ + +K +
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 171 KAQEEYEQIQAKRAAK-----KQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQ 223
+ ++E EQ Q +R + ++E R ++E ++ +RQ + +K + L ++ ++ Q
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Score = 28.1 bits (61), Expect = 7.1
Identities = 30/158 (18%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER-HRKQARKVDHPLS 116
R+ L+ +Q ++ R K + L SQ +R +L EE++ HR+Q ++
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERK-------FLEEEQQLHRQQRQRKFLQEE 1537
Query: 117 EQVHQPLLEEQCSID-EPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEE 175
+Q+ + +Q D + F ++ Q + E+Q ++ ++K + E
Sbjct: 1538 QQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL-------------SRQERDRKFRLE 1584
Query: 176 YEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFK 213
++++ + +K + ++ R+E Q+Q ++++ F+
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/165 (18%), Positives = 72/165 (43%), Gaps = 15/165 (9%)
Query: 62 KIQQSYKKLLRKEKKAQTSLES---QFTDRYPDNL-KHLYLAEEERHRKQARKVDHPLSE 117
+++Q K+ +E++ Q E Q +R + K + E E +Q++ P +
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 118 QVHQPLLEEQ-----CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKA 172
+ + E++ + E++ + Q Q EEQ + +K+++ A
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 173 ------QEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
Q E + +R ++Q F ++E+E+ +RQ ++++ E+
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 47.0 bits (110), Expect = 1e-05
Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 31/200 (15%)
Query: 60 KLKIQQSYKKLL---------RKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARK 110
KLK ++ +K+L ++EKK Q + D + K LAEE+ +K A K
Sbjct: 571 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK 630
Query: 111 VDHPL-----SEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK 165
+ E+ + L Q +E ++ + + +E+ K + K
Sbjct: 631 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA--------K 682
Query: 166 KTSNQKAQEEYEQ---IQAKRAAKKQEFERRKQERE--EAQRQYKKKKMEVFKILNKKTK 220
+ + Q+ QE EQ Q +R +++E ERR+QER+ E +R+ ++++++ + L ++ K
Sbjct: 683 RLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREK 742
Query: 221 KGQPNLNVQMEYLLQKIQEK 240
L +Q E L ++++EK
Sbjct: 743 A----LRLQKEQLQRELEEK 758
Score = 29.3 bits (64), Expect = 3.2
Identities = 21/79 (26%), Positives = 43/79 (54%), Gaps = 16/79 (20%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAK-----------KQEFERRK----QEREEAQRQYK 205
+K +++ N + +EE EQ++ ++ + K+E RK +ER E ++ K
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 206 KKKMEV-FKILNKKTKKGQ 223
KK++E F +++KT+K +
Sbjct: 596 KKQIEQKFAQIDEKTEKAK 614
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 47.0 bits (110), Expect = 1e-05
Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 31/200 (15%)
Query: 60 KLKIQQSYKKLL---------RKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARK 110
KLK ++ +K+L ++EKK Q + D + K LAEE+ +K A K
Sbjct: 567 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK 626
Query: 111 VDHPL-----SEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK 165
+ E+ + L Q +E ++ + + +E+ K + K
Sbjct: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA--------K 678
Query: 166 KTSNQKAQEEYEQ---IQAKRAAKKQEFERRKQERE--EAQRQYKKKKMEVFKILNKKTK 220
+ + Q+ QE EQ Q +R +++E ERR+QER+ E +R+ ++++++ + L ++ K
Sbjct: 679 RLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREK 738
Query: 221 KGQPNLNVQMEYLLQKIQEK 240
L +Q E L ++++EK
Sbjct: 739 A----LRLQKEQLQRELEEK 754
Score = 29.3 bits (64), Expect = 3.2
Identities = 21/79 (26%), Positives = 43/79 (54%), Gaps = 16/79 (20%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAK-----------KQEFERRK----QEREEAQRQYK 205
+K +++ N + +EE EQ++ ++ + K+E RK +ER E ++ K
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591
Query: 206 KKKMEV-FKILNKKTKKGQ 223
KK++E F +++KT+K +
Sbjct: 592 KKQIEQKFAQIDEKTEKAK 610
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 47.0 bits (110), Expect = 1e-05
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 99 AEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFT 158
A ER RK+ + + + EQ E+ +DE L + QP PEE +
Sbjct: 457 AAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE---KQPSPEEIREREREKER 513
Query: 159 IPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKK 218
+K +K Q+ ++E E+ + ++ K++E E+ ++++ E +++ K++K + + +K
Sbjct: 514 EREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEK 573
Query: 219 TKKGQPNLNVQMEYLLQKIQEK 240
K+ Q + E L+K +EK
Sbjct: 574 EKELQKMKEQEKECELEKEREK 595
Score = 34.3 bits (77), Expect = 0.099
Identities = 27/178 (15%), Positives = 87/178 (48%), Gaps = 19/178 (10%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLY----LAEEERHRKQARKVDH 113
R++ +I + ++ ++ ++ + +E Q + LK L + E++ ++ R+ +
Sbjct: 450 RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
Query: 114 PLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQ 173
+ + L +EQ E + ++ + E+ + ++ +++ ++ Q
Sbjct: 510 EKEREREKELEKEQ--------EQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561
Query: 174 EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQME 231
E+ ++++ ++ K++E ++ K++ +E + + +++K+E +K + +PNL +E
Sbjct: 562 EKEKELE-RQKEKEKELQKMKEQEKECELEKEREKLE------EKIEPREPNLEPMVE 612
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 46.6 bits (109), Expect = 2e-05
Identities = 44/166 (26%), Positives = 80/166 (48%), Gaps = 19/166 (11%)
Query: 64 QQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHR--KQARKVDHPLSEQVHQ 121
+ S KK RK+K+ + S S + D+ +E+E + K+ +K + +
Sbjct: 85 ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQS 144
Query: 122 PLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKK-----NKKKTSNQKAQEEY 176
E + E + + + S D+ + E K V S + +K +K +S ++ +Y
Sbjct: 145 STHESESESKESVKKKKKSKDETEKE----KDVRSLSKKRKKSYPDDKPLSSESSSESDY 200
Query: 177 EQ-IQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKK 221
E+ +QAK+ +RR +ERE+A+ + KKKK + K +KK KK
Sbjct: 201 EEDVQAKK-------KRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 43.9 bits (102), Expect = 1e-04
Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLA---EEERHRKQARKVDHP 114
R K+K ++ R+EK Q E Q D L+ L L+ +E R R+Q K+
Sbjct: 69 REKMKEEKRRSLEARREKLRQLMQEEQ--DLLARELEELRLSMNLQERRIREQHGKLKSA 126
Query: 115 LSEQ---VHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQK 171
EQ + + LL E + P + D Q VNS+ + K+ KK+
Sbjct: 127 KEEQRKLIAEQLLYEHWKKNNPKLREM-ELDLHQKH-----VVNSWEMQKEEKKQQEATA 180
Query: 172 AQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYK------KKKMEVFKILN---KKTKKG 222
QE A+++ ER K E E Q + K ++ME K+ K KK
Sbjct: 181 EQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKE 240
Query: 223 QPNLNVQMEYLLQKIQEK 240
Q NL ++ + L++++E+
Sbjct: 241 QENL-LKQRWELERLEEE 257
Score = 28.9 bits (63), Expect = 4.2
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 12/155 (7%)
Query: 69 KLLRKEKKAQTSLESQFTDRYPDNLKHL-------YLAEEERHRKQARKVDHPLSEQVHQ 121
++ ++EKK Q + Q RY + + AEEER + + + L +Q+ +
Sbjct: 167 EMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEE 226
Query: 122 PLLEEQCSI-----DEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEY 176
L+E + E L + + ++ + E + ++ + + N +
Sbjct: 227 LKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRT 286
Query: 177 EQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
+QIQ + A ++ + ++ +E+QR + ++ +V
Sbjct: 287 QQIQEELEADRRILQALLEKEDESQRLHLARREQV 321
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 43.9 bits (102), Expect = 1e-04
Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLA---EEERHRKQARKVDHP 114
R K+K ++ R+EK Q E Q D L+ L L+ +E R R+Q K+
Sbjct: 69 REKMKEEKRRSLEARREKLRQLMQEEQ--DLLARELEELRLSMNLQERRIREQHGKLKSA 126
Query: 115 LSEQ---VHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQK 171
EQ + + LL E + P + D Q VNS+ + K+ KK+
Sbjct: 127 KEEQRKLIAEQLLYEHWKKNNPKLREM-ELDLHQKH-----VVNSWEMQKEEKKQQEATA 180
Query: 172 AQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYK------KKKMEVFKILN---KKTKKG 222
QE A+++ ER K E E Q + K ++ME K+ K KK
Sbjct: 181 EQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKE 240
Query: 223 QPNLNVQMEYLLQKIQEK 240
Q NL ++ + L++++E+
Sbjct: 241 QENL-LKQRWELERLEEE 257
Score = 28.9 bits (63), Expect = 4.2
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 12/155 (7%)
Query: 69 KLLRKEKKAQTSLESQFTDRYPDNLKHL-------YLAEEERHRKQARKVDHPLSEQVHQ 121
++ ++EKK Q + Q RY + + AEEER + + + L +Q+ +
Sbjct: 167 EMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEE 226
Query: 122 PLLEEQCSI-----DEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEY 176
L+E + E L + + ++ + E + ++ + + N +
Sbjct: 227 LKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRT 286
Query: 177 EQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
+QIQ + A ++ + ++ +E+QR + ++ +V
Sbjct: 287 QQIQEELEADRRILQALLEKEDESQRLHLARREQV 321
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/227 (21%), Positives = 107/227 (47%), Gaps = 20/227 (8%)
Query: 34 QKTWRPNHP-QAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDN 92
+K WR + G +RE + +R++ ++++ K+L +EK+ + E + +
Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352
Query: 93 LKHLYLAEEERHRKQARKV---DHPLSEQVHQPLLEEQCSID--EPLFEDQCSF----DQ 143
+ +EE+ R+Q K+ + L EQ Q +EQ D E ++E ++
Sbjct: 353 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 412
Query: 144 PQPEEQCIKTVNSFTIPKK---NKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREE 199
+ +E+ + V KK +KKT +Q+ + +E E+I+ + ++E E +++ E+
Sbjct: 413 MREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Query: 200 AQRQ------YKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
Q+Q ++K+ + ++ +K K + + E + + +EK
Sbjct: 473 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Score = 40.0 bits (92), Expect = 0.002
Identities = 33/172 (19%), Positives = 81/172 (47%), Gaps = 6/172 (3%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLS- 116
R + K Q+ KK +E+K + + ++ + + +EE+ ++Q K+
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 117 ----EQVHQPLLEEQCSIDEPLFE-DQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQK 171
E+ Q E+ +E ++E ++ ++Q + EQ K + ++ K + +K
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 172 AQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQ 223
E+ + + + +K+ +++ K EE+ R+ +KK E +++ ++ +K Q
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/163 (22%), Positives = 82/163 (50%), Gaps = 9/163 (5%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE + ++ K+Q+ +K+ +E+K Q E + + + E++R +Q
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664
Query: 109 RKV-DHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKT 167
K+ +H ++ Q ++EQ +E ++E + + Q +E+ KT + + ++ +
Sbjct: 665 EKLWEHEKMQE--QEKMQEQ---EEKIWEQEKMEKKTQEQEK--KTWDQEKMREEESMRE 717
Query: 168 SNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKME 210
+K +EE E++ ++ K QE E + QE+EE + ++K E
Sbjct: 718 REKKMREE-EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Score = 37.0 bits (84), Expect = 0.015
Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Query: 28 RNKNVRQKTWRPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTD 87
+ + +KTW +RE + + +++ +K+ +E+K Q E +
Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ 629
Query: 88 RYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPE 147
+ +EE+ +Q K+ + Q L EQ E L+E + +Q + +
Sbjct: 630 ------EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ---KEKLWEHEKMQEQEKMQ 680
Query: 148 EQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQR-QYKK 206
EQ K + KK +++ QE+ + ++ R +K+ E + RE+ ++ Q ++
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 207 KKME 210
+KM+
Sbjct: 741 EKMQ 744
Score = 35.4 bits (80), Expect = 0.045
Identities = 48/207 (23%), Positives = 90/207 (43%), Gaps = 32/207 (15%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSE 117
R + K+Q+ KK +E+K Q + ++ + +EE+ +KQ + +
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 118 QVHQPLLEEQCSIDEPLFEDQCSFDQPQPE-EQCIKTVNSFTIPKKNKKKTSNQKAQEEY 176
+ Q L EQ E L+E + +Q + EQ K + + + KK +K +E+
Sbjct: 487 EWQQQRLPEQ---KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 177 EQI----------------QAKRAAKK-QEFERR------KQEREEAQRQYKKKKMEVFK 213
+Q+ Q +R KK QE E++ K EE R+ +KK E +
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Query: 214 ILNKKTKKGQPNLNVQMEYLLQKIQEK 240
++ ++ +K Q + E +Q+ +EK
Sbjct: 604 MMREQEEKMQ-----EQEEKMQEQEEK 625
Score = 35.0 bits (79), Expect = 0.058
Identities = 38/183 (20%), Positives = 77/183 (42%), Gaps = 33/183 (18%)
Query: 59 RKLKIQQSYKKLLRKEKKAQTSLESQFTD--------RYPDNLKHLYLAEEERHRKQARK 110
R+ K+++ + + +E+K Q E+ + R P+ + L+ E+E+ ++Q K
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW--EQEKMQEQEEK 512
Query: 111 V----------------------DHPLSEQVHQPLLEEQCSID-EPLFEDQCSFDQPQPE 147
+ + EQ Q +E+ D E DQ + + +
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Query: 148 EQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKK 207
EQ KT + ++ ++ +K E E++ ++ K QE E + QE+EE + ++K
Sbjct: 573 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 208 KME 210
E
Sbjct: 633 MQE 635
Score = 33.9 bits (76), Expect = 0.13
Identities = 37/175 (21%), Positives = 82/175 (46%), Gaps = 10/175 (5%)
Query: 42 PQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLES--QFTDRYPDNLKHLYLA 99
PQ +++E +R++ ++++ KK+ ++E+K E + + + + ++
Sbjct: 263 PQVQTNTLQEEM---WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ 319
Query: 100 EEE--RHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSF 157
E+ K+ R+ + L EQ EEQ E +Q + Q E+ + +
Sbjct: 320 EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 158 TIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQER--EEAQRQYKKKKME 210
K+ +++ + QEE Q +R +K+E R+QE+ E+ ++ ++KKM+
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEE-RMREQEKMWEQVEKMREEKKMQ 433
Score = 32.3 bits (72), Expect = 0.38
Identities = 34/173 (19%), Positives = 78/173 (45%), Gaps = 16/173 (9%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTD-RYPDNLKHLYLAEEERHRKQ 107
++E + + ++ K+Q+ +K+ +E+K E + R P+ + L+ E+ + +++
Sbjct: 619 MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Query: 108 ARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKT 167
++ + + EQ +E++ E DQ + EE+ ++ ++ +
Sbjct: 679 MQEQEEKIWEQEK---MEKKTQEQEKKTWDQ----EKMREEESMREREKKMREEEEMMRE 731
Query: 168 SNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTK 220
+K QE+ E K QE E E+EE + ++K E ++ +K K
Sbjct: 732 QEEKMQEQEE--------KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Score = 32.0 bits (71), Expect = 0.49
Identities = 41/210 (19%), Positives = 84/210 (40%), Gaps = 37/210 (17%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER----- 103
+RE + +R++ ++ + K++ +E+K + E + K + E+E+
Sbjct: 364 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQV 423
Query: 104 -----------HRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPE---EQ 149
K+ R + + E+ E++ +E +Q Q Q E EQ
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 483
Query: 150 CIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAK------------------RAAKKQEFE 191
K +P++ +K +K QE+ E+I + R K +E E
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 192 RRKQEREEAQRQYKKKKMEVFKILNKKTKK 221
+ E+EE R ++K + + + KKT++
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Score = 28.5 bits (62), Expect = 5.5
Identities = 29/149 (19%), Positives = 69/149 (46%), Gaps = 12/149 (8%)
Query: 62 KIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQ 121
K+Q+ +K+ +EK + + E + + ++ E R R++ + + + + +
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE---EESMREREKKMREEEEMMREQEE 734
Query: 122 PLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQA 181
+ E++ + E E++ + + EQ K +P++ +K ++K QE+ E+I
Sbjct: 735 KMQEQEEKMQEQ--EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ-EKIW- 790
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKME 210
+QE + R QE + ++ K + E
Sbjct: 791 -----EQEEKMRDQEEKMRGQEEKMRGQE 814
Score = 28.1 bits (61), Expect = 7.1
Identities = 33/182 (18%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 62 KIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQ 121
K+Q+ +K+ +E+K + E ++ + + E++ ++ + D +
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 122 PLLEEQCSIDEPLFEDQCSF--DQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQ-EEYEQ 178
+E++ E DQ ++ + E+ K + ++ ++K Q+ + +E E+
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Query: 179 IQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQ 238
++ K QE E + E+EE + ++K E ++ +K K + + +Q + +Q+ +
Sbjct: 625 KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE-HEKMQEQEKMQEQE 683
Query: 239 EK 240
EK
Sbjct: 684 EK 685
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 42.7 bits (99), Expect = 3e-04
Identities = 32/133 (24%), Positives = 71/133 (53%), Gaps = 18/133 (13%)
Query: 92 NLKHLYLAEEERHRKQARKVDHPLSE---QVHQPLLEEQCSIDEPLFEDQCSFDQPQPEE 148
N H E R++++ R+ L++ + LL+ Q S ++P +D+ + +P E+
Sbjct: 485 NHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDP--KDEPAELKPDSED 542
Query: 149 QCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKK 208
+ + ++++ +QE+ +I++KR +++E ERR++ERE + + K+K+
Sbjct: 543 L-------------SSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKE 589
Query: 209 MEVFKILNKKTKK 221
E K K+++K
Sbjct: 590 REREKQKLKESEK 602
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 42.4 bits (98), Expect = 4e-04
Identities = 36/149 (24%), Positives = 69/149 (46%), Gaps = 19/149 (12%)
Query: 100 EEERHRKQARKVDHPLSEQVHQ--PLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSF 157
E E+ +K+ KV+ L E+ + ++ EQ I++ + E +Q +P+ K S
Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307
Query: 158 TIPKKNKKKTSNQKAQEEY------------EQIQAKRAAKKQEFERRKQEREEAQRQ-- 203
I K K S Q AQ+ Y E + ++A +QEFE R +E ++Q +
Sbjct: 308 KIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKA--RQEFEERMEEESQSQGRDL 365
Query: 204 -YKKKKMEVFKILNKKTKKGQPNLNVQME 231
++ +++ + L ++ K L ++E
Sbjct: 366 TLEENQVKKYHRLKEEASKRAATLAQELE 394
Score = 33.5 bits (75), Expect = 0.17
Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 23/169 (13%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSL------ESQFTDRYPDNLKHLYLAEEER----HRKQ 107
R L Q + + + K K +T+L + Y K + AEE+ HRK+
Sbjct: 131 RNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKK 190
Query: 108 ARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTV-NSFTIPKKNKKK 166
+ ++Q + Q DE + + Q + Q K N I K NK+
Sbjct: 191 NIAAERKEAKQEKEEADRYQRLKDEVV--------RAQVQLQLFKLYHNEVEIEKLNKEL 242
Query: 167 TSNQKAQEE----YEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
S K E+ ++++ + KK+E + +E+++ +++ K+K E+
Sbjct: 243 ASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Score = 30.4 bits (67), Expect = 1.4
Identities = 40/174 (22%), Positives = 76/174 (43%), Gaps = 27/174 (15%)
Query: 59 RKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNL----KHLYLAEEERHRKQARKVDHP 114
R ++ Q Y K RK++ + ++QF N+ K +EE R Q K D
Sbjct: 160 RSGELAQEYDK--RKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLK-DEV 216
Query: 115 LSEQVH-------------QPLLEEQCSIDEPLFEDQCSFDQPQPE-----EQCIKTVNS 156
+ QV + L +E S ++ + +D+ D+ + E ++ K +
Sbjct: 217 VRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE 276
Query: 157 FTIPKKNKKKTSNQKAQEEYEQIQAKR--AAKKQEFERRKQEREEAQRQYKKKK 208
+K K+ ++ Q+ + I+AK + K ++ E K+ + AQ+ YKK+K
Sbjct: 277 QQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRK 330
Score = 30.0 bits (66), Expect = 1.9
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 10/80 (12%)
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTS--------NQKAQEEYEQIQAKRAAKKQEFERRKQE 196
Q EE+ + +N T+ +K ++ S N KA E+ E ++ K EFE ++
Sbjct: 994 QAEEEIKQEMN--TLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKR 1051
Query: 197 REEAQRQYKKKKMEVFKILN 216
++A++ +++ K E F N
Sbjct: 1052 AKKAKQAFEQIKKERFDRFN 1071
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 42.0 bits (97), Expect = 5e-04
Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 3/146 (2%)
Query: 65 QSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLL 124
Q ++ +RK+++ E Q ++ LK E+E + + EQ+ +
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ-- 308
Query: 125 EEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRA 184
EEQ E +Q + EEQ + K+ K Q ++E + + +
Sbjct: 309 EEQMREQEEQMREQ-EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ 367
Query: 185 AKKQEFERRKQEREEAQRQYKKKKME 210
+KQE + RKQE + +++ + +K E
Sbjct: 368 VRKQEEQMRKQEEQMRKQEEQMRKQE 393
Score = 33.5 bits (75), Expect = 0.17
Identities = 35/193 (18%), Positives = 85/193 (44%), Gaps = 10/193 (5%)
Query: 47 GSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRK 106
G VRE +G ++ ++++ ++ +E + + E + R + +
Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEG 178
Query: 107 QARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKK 166
Q R+ + + EQ Q + E++ + E E+Q + EEQ K ++ +K
Sbjct: 179 QVREQEGQVREQEGQ-MGEQEGQMGEQ--EEQMG----EQEEQMQKQEEQMGEQEEQMRK 231
Query: 167 TSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNL 226
Q ++E + + + +KQE + RKQE + +++ + ++ E + K+ + +
Sbjct: 232 QEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQT 291
Query: 227 NVQMEYLLQKIQE 239
Q E + ++ ++
Sbjct: 292 GEQEEQMREQEEQ 304
Score = 33.1 bits (74), Expect = 0.22
Identities = 32/164 (19%), Positives = 72/164 (43%), Gaps = 18/164 (10%)
Query: 47 GSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRK 106
G VRE +G ++ ++ + +++ +E++ Q E + + E+E +
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE---E 241
Query: 107 QARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKK 166
Q +K + + +Q EEQ E +Q + EEQ +K +K + +
Sbjct: 242 QVQKQEEQVQKQ------EEQMRKQEEQMREQ-EEQMREQEEQMLK--------QKEQTE 286
Query: 167 TSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKME 210
Q ++E + + + ++QE + R+QE + +++ + K E
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330
Score = 29.6 bits (65), Expect = 2.5
Identities = 29/164 (17%), Positives = 78/164 (47%), Gaps = 18/164 (10%)
Query: 47 GSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRK 106
G VRE +G ++ ++++ ++ R+++ E Q ++ + E+E +
Sbjct: 164 GQVREQEGQVREQEGQVREQEGQV-REQEGQMGEQEGQMGEQEEQ------MGEQE---E 213
Query: 107 QARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKK 166
Q +K + + EQ Q +E E + E + +Q Q +E+ ++ ++ + +
Sbjct: 214 QMQKQEEQMGEQEEQMRKQE-----EQMGEQE---EQVQKQEEQVQKQEEQMRKQEEQMR 265
Query: 167 TSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKME 210
++ +E+ EQ+ ++ +QE + +QE + +++ + ++ E
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQE 309
Score = 28.5 bits (62), Expect = 5.5
Identities = 33/194 (17%), Positives = 83/194 (42%), Gaps = 5/194 (2%)
Query: 47 GSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRK 106
G VRE +G ++ ++++ ++ +E + + E + R + +
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEG 185
Query: 107 QARKVDHPLSEQVHQP-LLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK 165
Q R+ + + EQ Q EEQ E + Q + EEQ K ++ +
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ-EEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 166 KTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPN 225
K Q ++E + + + ++QE + R+QE + +++ + ++ E ++ ++ +
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Query: 226 LNVQMEYLLQKIQE 239
+ Q E + ++ ++
Sbjct: 305 MREQEEQMREQEEQ 318
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 42.0 bits (97), Expect = 5e-04
Identities = 20/61 (32%), Positives = 38/61 (62%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTK 220
KK K+T +K +EE E+ + ++ KK+E E R++E EE + + ++++ E + KK K
Sbjct: 43 KKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102
Query: 221 K 221
+
Sbjct: 103 R 103
Score = 39.3 bits (90), Expect = 0.003
Identities = 21/61 (34%), Positives = 38/61 (62%), Gaps = 3/61 (4%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTK 220
K+ KKK ++ +EE E+ + K +K+E RRK+++ +R+ K+++ E K +KTK
Sbjct: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK---KRRRKEEEEEKKKKRRRKTK 121
Query: 221 K 221
K
Sbjct: 122 K 122
Score = 38.1 bits (87), Expect = 0.007
Identities = 21/61 (34%), Positives = 36/61 (59%), Gaps = 3/61 (4%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTK 220
KK KK+T + EE E+ + K +K E+RK++R+E +++ K K+ E K ++ K
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRK---EKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 221 K 221
K
Sbjct: 61 K 61
Score = 38.1 bits (87), Expect = 0.007
Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 5/61 (8%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTK 220
KK K+K +K +EE E+ + +++E E+ ++E+EE +R+ KKKK + +K K
Sbjct: 60 KKRKRKRKKKKEEEEREEEE-----EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Query: 221 K 221
K
Sbjct: 115 K 115
Score = 37.4 bits (85), Expect = 0.012
Identities = 19/61 (31%), Positives = 39/61 (63%), Gaps = 1/61 (1%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTK 220
K+ KKKT + ++E E+ + KR K+++ ++ ++EREE + + +++K E K ++ K
Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98
Query: 221 K 221
K
Sbjct: 99 K 99
Score = 35.4 bits (80), Expect = 0.045
Identities = 19/80 (23%), Positives = 43/80 (53%)
Query: 161 KKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTK 220
KK ++T + EE E+ + KR K++E + K+++++ + K+K+ E + K+ +
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 221 KGQPNLNVQMEYLLQKIQEK 240
K + + E ++ +EK
Sbjct: 67 KKKKEEEEREEEEEEEEEEK 86
Score = 32.3 bits (72), Expect = 0.38
Identities = 14/53 (26%), Positives = 32/53 (60%)
Query: 158 TIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKME 210
T ++ K+ +K +E+ ++ + K+ K+ E + K+E E+ +++ +KKK E
Sbjct: 19 TEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71
Score = 32.3 bits (72), Expect = 0.38
Identities = 28/125 (22%), Positives = 52/125 (41%), Gaps = 22/125 (17%)
Query: 64 QQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPL 123
++ K+ RKEK+ + E + + + K EEE+ RK+ RK E+ +
Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80
Query: 124 LEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKR 183
EE+ +E E + ++ KKK +K +EE ++ + +R
Sbjct: 81 EEEEEKEEEEKEEGR----------------------RRKKKKKRRRKEEEEEKKKKRRR 118
Query: 184 AAKKQ 188
KK+
Sbjct: 119 KTKKK 123
Score = 30.8 bits (68), Expect = 1.1
Identities = 15/45 (33%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Query: 164 KKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKK 208
KKK +K EE E+ + +++E +RK++R+E +++ +KKK
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKE-GKRKEKRKEKRKEKEKKK 44
Score = 30.8 bits (68), Expect = 1.1
Identities = 30/136 (22%), Positives = 64/136 (47%), Gaps = 18/136 (13%)
Query: 72 RKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSID 131
+K+KK + + E++ T+ + E+E RK+ RK E+ + E+
Sbjct: 2 KKKKKKKETEETEETEETEEE------EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55
Query: 132 EPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFE 191
E + + + + EE+ ++ +++ +K +EE E+ R KK++
Sbjct: 56 EEEEKKRKRKRKKKKEEE---------EREEEEEEEEEEKEEEEKEE---GRRRKKKKKR 103
Query: 192 RRKQEREEAQRQYKKK 207
RRK+E EE +++ ++K
Sbjct: 104 RRKEEEEEKKKKRRRK 119
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 41.6 bits (96), Expect = 6e-04
Identities = 42/203 (20%), Positives = 89/203 (43%), Gaps = 30/203 (14%)
Query: 50 REGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQAR 109
R+ + F+ + + + + K + EKK +++ Q D+ D L +EE+ K+
Sbjct: 193 RDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDELY-----KEEKIWKEKF 247
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKT-- 167
K +H + EE+ F+DQ Q + + +K N+ + + K K
Sbjct: 248 KQHEEYIRNLHLQMEEERTR-----FKDQ----QEKEKNSLLKQQNNAAVKIQAKYKAFV 298
Query: 168 --------------SNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFK 213
S ++ +E+++ +AK K++E +R +E + + + KK+K E K
Sbjct: 299 AYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERK 358
Query: 214 ILNKKTKKGQPNLNVQMEYLLQK 236
K+ ++ + + + E L+ K
Sbjct: 359 RREKEYEEKKNIVKQEREQLISK 381
Score = 36.6 bits (83), Expect = 0.020
Identities = 38/182 (20%), Positives = 82/182 (45%), Gaps = 19/182 (10%)
Query: 66 SYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLE 125
SY + +T L +++ + +K L+E E+ K D + V +P
Sbjct: 84 SYGAVSNNHMHLRTGLSTEYEESSEQLIK--ILSEIEKEEFMRSKTDCATPDFVPEPSPH 141
Query: 126 EQCSIDEPLFEDQC--SFDQPQPEEQCIKTVNSFTIPKKNKK-------KTSNQKAQEEY 176
+ +DE + D +F + EE+C ++ ++ +K + K + ++++
Sbjct: 142 D-LPMDEHVLPDDADINFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQF 200
Query: 177 EQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVF----KILNKKTKKGQP---NLNVQ 229
++ + KR ++F+ K++ E Q+Q + K + KI +K K+ + NL++Q
Sbjct: 201 QEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQ 260
Query: 230 ME 231
ME
Sbjct: 261 ME 262
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 41.6 bits (96), Expect = 6e-04
Identities = 42/203 (20%), Positives = 89/203 (43%), Gaps = 30/203 (14%)
Query: 50 REGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQAR 109
R+ + F+ + + + + K + EKK +++ Q D+ D L +EE+ K+
Sbjct: 193 RDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDELY-----KEEKIWKEKF 247
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKT-- 167
K +H + EE+ F+DQ Q + + +K N+ + + K K
Sbjct: 248 KQHEEYIRNLHLQMEEERTR-----FKDQ----QEKEKNSLLKQQNNAAVKIQAKYKAFV 298
Query: 168 --------------SNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFK 213
S ++ +E+++ +AK K++E +R +E + + + KK+K E K
Sbjct: 299 AYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERK 358
Query: 214 ILNKKTKKGQPNLNVQMEYLLQK 236
K+ ++ + + + E L+ K
Sbjct: 359 RREKEYEEKKNIVKQEREQLISK 381
Score = 36.6 bits (83), Expect = 0.020
Identities = 38/182 (20%), Positives = 82/182 (45%), Gaps = 19/182 (10%)
Query: 66 SYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLE 125
SY + +T L +++ + +K L+E E+ K D + V +P
Sbjct: 84 SYGAVSNNHMHLRTGLSTEYEESSEQLIK--ILSEIEKEEFMRSKTDCATPDFVPEPSPH 141
Query: 126 EQCSIDEPLFEDQC--SFDQPQPEEQCIKTVNSFTIPKKNKK-------KTSNQKAQEEY 176
+ +DE + D +F + EE+C ++ ++ +K + K + ++++
Sbjct: 142 D-LPMDEHVLPDDADINFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQF 200
Query: 177 EQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVF----KILNKKTKKGQP---NLNVQ 229
++ + KR ++F+ K++ E Q+Q + K + KI +K K+ + NL++Q
Sbjct: 201 QEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQ 260
Query: 230 ME 231
ME
Sbjct: 261 ME 262
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2448 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2506
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2507 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2534
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2535 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2589
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2590 ENQRLREQLQ 2599
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 1967 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 2026
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 2027 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2141
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 2031 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2090
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2151 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2197
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1500 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1558
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1559 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1598
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1599 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1631
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2382 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2559
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2560 HEAEEGVRRKQEELQQLEQQRRQQ 2583
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2227 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2286
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2287 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2343
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2389
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2452 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2510
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2511 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2538
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2539 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2593
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2594 ENQRLREQLQ 2603
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 1971 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 2030
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 2031 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2090
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2091 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2145
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 2035 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2094
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2095 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2154
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2155 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2201
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1504 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1562
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1563 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1602
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1603 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1635
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2386 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2443
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2444 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2503
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2504 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2563
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2564 HEAEEGVRRKQEELQQLEQQRRQQ 2587
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2231 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2290
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2291 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2347
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2348 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2393
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2448 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2506
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2507 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2534
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2535 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2589
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2590 ENQRLREQLQ 2599
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 1967 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 2026
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 2027 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2141
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 2031 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2090
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2151 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2197
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1500 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1558
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1559 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1598
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1599 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1631
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2382 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2500 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2559
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2560 HEAEEGVRRKQEELQQLEQQRRQQ 2583
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2227 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2286
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2287 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2343
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2389
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2416 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2474
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2475 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2502
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2503 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2557
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2558 ENQRLREQLQ 2567
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 1935 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 1994
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 1995 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2054
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2055 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2109
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 1999 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2058
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2059 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2118
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2119 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2165
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1468 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1526
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1527 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1566
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1567 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1599
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2350 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2407
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2408 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2467
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2468 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2527
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2528 HEAEEGVRRKQEELQQLEQQRRQQ 2551
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2195 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2254
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2255 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2311
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2312 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2357
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2585 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2643
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2644 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2671
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2672 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2726
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2727 ENQRLREQLQ 2736
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 2104 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 2163
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 2164 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2223
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2224 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2278
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 2168 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2227
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2228 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2287
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2288 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2334
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1637 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1695
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1696 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1735
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1736 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1768
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2519 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2577 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2636
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2637 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2696
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2697 HEAEEGVRRKQEELQQLEQQRRQQ 2720
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2364 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2423
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2424 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2480
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2481 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2526
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2426 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2484
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2485 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2512
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2513 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2567
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2568 ENQRLREQLQ 2577
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 1945 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 2004
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 2005 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2064
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2065 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2119
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 2009 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2068
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2069 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2128
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2129 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2175
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1478 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1536
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1537 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1576
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1577 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1609
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2360 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2417
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2418 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2477
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2478 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2537
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2538 HEAEEGVRRKQEELQQLEQQRRQQ 2561
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2205 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2264
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2265 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2321
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2322 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2367
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2434 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2492
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2493 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2520
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2521 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2575
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2576 ENQRLREQLQ 2585
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 1953 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 2012
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 2013 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2072
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2073 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2127
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 2017 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2076
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2077 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2136
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2137 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2183
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1486 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1544
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1545 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1584
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1585 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1617
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2368 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2425
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2426 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2485
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2486 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2545
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2546 HEAEEGVRRKQEELQQLEQQRRQQ 2569
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2213 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2272
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2273 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2329
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2330 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2375
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 41.2 bits (95), Expect = 8e-04
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 38/190 (20%)
Query: 49 VREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQA 108
+RE R K K+QQ K L K ++ QT + Q L+ +L+E++ ++
Sbjct: 2475 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQE-TQALQQSFLSEKDSLLQRE 2533
Query: 109 RKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTS 168
R +E++ + E LF+D+ + Q EEQ
Sbjct: 2534 R-------------FIEQEKAKLEQLFQDEVAKAQQLREEQ------------------- 2561
Query: 169 NQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNV 228
Q+ Q++ EQ + + A +E RR+ E EE R +K E + L ++ ++ + L
Sbjct: 2562 -QRQQQQMEQERQRLVASMEEARRRQHEAEEGVR----RKQEELQQLEQQRRQQEELLAE 2616
Query: 229 QMEYLLQKIQ 238
+ + L +++Q
Sbjct: 2617 ENQRLREQLQ 2626
Score = 34.7 bits (78), Expect = 0.076
Identities = 39/179 (21%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 71 LRKEKKAQTSLESQFTDRYPDNLKHLYLAEEE---RHRKQARKVDHPLSEQVHQPLLEEQ 127
L ++ Q + E + R + LA EE R RK A + L +V + +
Sbjct: 1994 LEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE 2053
Query: 128 CSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKK-KTSNQKAQEEYEQIQ-----A 181
+ E + Q + + Q Q + ++F + +K ++ + + Q+ Q +Q++ A
Sbjct: 2054 RAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAA 2113
Query: 182 KRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+RAA++ E R + ERE AQ + + ++ E K++ + Q Q + +K++++
Sbjct: 2114 RRAAEEAEEARVQAEREAAQSRRQVEEAERL----KQSAEEQAQARAQAQAAAEKLRKE 2168
Score = 32.7 bits (73), Expect = 0.29
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 91 DNLKHLYLAEEERHRK-QARKVDHPLS-----EQVHQPLLEEQCSIDEPLFEDQCSFDQP 144
++ + L LA+E ++ QA + H + +++ Q L +EQ +D+ E + +
Sbjct: 2058 ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAA 2117
Query: 145 QPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEA---- 200
+ E+ + + + + + Q EQ QA+ A+ + RK+ +EA
Sbjct: 2118 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2177
Query: 201 --------QRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
Q+Q +ME K ++T + + + ++ L +++E
Sbjct: 2178 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE 2224
Score = 28.1 bits (61), Expect = 7.1
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 28/157 (17%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFT---DRYPDNLKHLYLAEEERHRKQARKVDHP 114
RR+++ + K+ E ++ E++ R L+ L L EE R+ R+ +
Sbjct: 1527 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERR-LRQAEVE 1585
Query: 115 LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQE 174
+ QV L Q S + L + SF + K + QE
Sbjct: 1586 RARQVQVALETAQRSAEAELQSKRASFAE--------------------KTAQLERSLQE 1625
Query: 175 EYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEV 211
E+ + A ++E ERR Q++ EA+R ++ + E+
Sbjct: 1626 EHVAV----AQLREEAERRAQQQAEAERAREEAEREL 1658
Score = 28.1 bits (61), Expect = 7.1
Identities = 39/204 (19%), Positives = 89/204 (43%), Gaps = 21/204 (10%)
Query: 56 AFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEER---------HRK 106
A R KL++ + + R E+ AQ + + + L LA +E+ R+
Sbjct: 2409 AERLKLRVAEMSRAQARAEEDAQRFRKQ--AEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 107 QARKVDHPLSEQV-----HQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPK 161
Q+ L E + + L+++ + + E+ + Q Q ++ SF K
Sbjct: 2467 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2526
Query: 162 ----KNKKKTSNQKAQ-EEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILN 216
+ ++ +KA+ E+ Q + +A + +E ++R+Q++ E +RQ ME +
Sbjct: 2527 DSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ 2586
Query: 217 KKTKKGQPNLNVQMEYLLQKIQEK 240
+ ++G +++ L Q+ +++
Sbjct: 2587 HEAEEGVRRKQEELQQLEQQRRQQ 2610
Score = 27.7 bits (60), Expect = 9.3
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 51 EGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRY-PDNLKHLYLAEEERHRKQAR 109
E + F+ R +++ K + E +A + T R+ + + + EE R
Sbjct: 2254 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2313
Query: 110 KVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSN 169
+ Q+ + L +Q ++ E + +++ Q E +K +K +
Sbjct: 2314 AQEAARLRQLAEEDLAQQRALAEKMLKEKM---QAVQEATRLKAEAELLQQQKELAQEQA 2370
Query: 170 QKAQEEYEQIQAKRAAKKQEFER----RKQEREEAQRQYKKKKMEV 211
++ QE+ EQ+ + A + Q F+R +Q + E + ++ K+ V
Sbjct: 2371 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2416
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/176 (21%), Positives = 88/176 (50%), Gaps = 28/176 (15%)
Query: 58 RRKLKIQQSYKKLLRKEKKA---QTSLESQFTDRYPDNLKHLYLAEEE---------RHR 105
R++ K+ ++++ KE+K ++ L + ++ D+ + + EEE R R
Sbjct: 2141 RKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKR 2200
Query: 106 KQARKVDHP---LSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKK 162
K+A++ D P S QV + EE S E + D+ + +E S + ++
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSE-----EMESLLDELEKQE-------SLSSEEE 2248
Query: 163 NKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKK 218
+++ ++ +EE + + +R +++E E ++ E+EE +++ KKK+ + ++ K+
Sbjct: 2249 EEREEEEEREEEEVREEEEERK-EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Score = 33.9 bits (76), Expect = 0.13
Identities = 38/194 (19%), Positives = 81/194 (41%), Gaps = 28/194 (14%)
Query: 59 RKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQ 118
++ ++ + KKL RK++K + K + EEE K ARK + +
Sbjct: 2128 KRSELTKDEKKLARKQRKLANKMRRMIN-------KEEKMTEEES--KLARKHSEVILDD 2178
Query: 119 VHQPLLEEQCSI----------------DEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKK 162
+ +EE+ I D+P + D+ + EE + + S +
Sbjct: 2179 EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELE 2238
Query: 163 NKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKG 222
++ S+++ +E E+ + + ++E E R +EE + + K+ + E + KK +K
Sbjct: 2239 KQESLSSEEEEEREEEEEREEEEVREEEEER---KEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 223 QPNLNVQMEYLLQK 236
+ + + E +K
Sbjct: 2296 KEEVQEKEEVFEEK 2309
Score = 33.9 bits (76), Expect = 0.13
Identities = 35/152 (23%), Positives = 70/152 (46%), Gaps = 4/152 (2%)
Query: 72 RKEKKAQTSLESQFTDRYPDNLKHLYLAEE-ERHRKQARKVDHPLSEQVHQPLLEEQCSI 130
RKE K + +F+ + + + +EE E + K + SE+ + EE+
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259
Query: 131 DEPLFEDQCSFDQPQPEEQCI-KTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQE 189
+E E++ ++ + EE+ + K KK KKK Q+ +E +E + + ++E
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE--EKEEIMSEEE 2317
Query: 190 FERRKQEREEAQRQYKKKKMEVFKILNKKTKK 221
E E EE + +++++ K + KK K+
Sbjct: 2318 TESLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349
Score = 30.4 bits (67), Expect = 1.4
Identities = 32/150 (21%), Positives = 68/150 (45%), Gaps = 26/150 (17%)
Query: 68 KKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLL--- 124
K+LL++E+K + E L+ EE ++ +K+ +QV + +L
Sbjct: 1487 KRLLQEEEKLHQAGEK--------------LSPEEEMLQEDKKLKWEEWKQVWENMLSSK 1532
Query: 125 --------EEQCSIDEPLFEDQCSFDQPQPEEQC-IKTVNSFTIPKKNKKKTSNQKAQEE 175
EE+ +++E + + +Q EEQ I+ + + + + + ++AQEE
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
Query: 176 YEQIQAKRAAKKQEFERRKQEREEAQRQYK 205
+ Q + ++E + ++ER+ AQ K
Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVK 1622
Score = 27.7 bits (60), Expect = 9.3
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 159 IPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKME 210
I KK +KKT + ++ + +Q +R K + E K+ER+ ++ + +E
Sbjct: 1387 ISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLE 1438
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/208 (20%), Positives = 90/208 (43%), Gaps = 18/208 (8%)
Query: 20 EGVSTVGYRNKNVRQKTWRPNHPQA--FVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKA 77
+G YR+++ + RP+ P+ F + ++ R + + LL KE++
Sbjct: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKERE- 123
Query: 78 QTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFED 137
++L+ L+E ER + LS + +P +E +++ +
Sbjct: 124 -------------ESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKK 170
Query: 138 QCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEF--ERRKQ 195
+ EE+ K+ S KK +KK S+++ ++Y + + + + E K+
Sbjct: 171 STTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKR 230
Query: 196 EREEAQRQYKKKKMEVFKILNKKTKKGQ 223
++A+++ KKKK K K++KK +
Sbjct: 231 RAKKAKKKEKKKKHRSKKYKKKRSKKSR 258
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/130 (26%), Positives = 66/130 (50%), Gaps = 11/130 (8%)
Query: 90 PDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQP--- 146
P + K+ ++E+ +K+ +++ + Q EE I+E E++ ++ +
Sbjct: 13 PSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLH 72
Query: 147 EEQCI---KTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQ 203
EE + K F I K +K+ + +K QEE E+ K + +E +R+++E EE +RQ
Sbjct: 73 EEWLLREQKAQEEFRI--KKEKEEAAKKRQEEQER---KLKEQWEEQQRKEREEEEQKRQ 127
Query: 204 YKKKKMEVFK 213
KK+K E +
Sbjct: 128 EKKEKEEALQ 137
Score = 28.9 bits (63), Expect = 4.2
Identities = 23/105 (21%), Positives = 46/105 (43%), Gaps = 10/105 (9%)
Query: 146 PEEQCIKTVNSFTIPKKNKKKTS----------NQKAQEEYEQIQAKRAAKKQEFERRKQ 195
PE+ K + +K KK+ +QK +EE I+ ++ +++ ER +Q
Sbjct: 10 PEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQ 69
Query: 196 EREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
E ++K E F+I +K + + Q L ++ +E+
Sbjct: 70 RLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQ 114
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 23/186 (12%)
Query: 58 RRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSE 117
RR+ ++Q+ ++ R EK+ Q LE + R + + L L EE R +++ RK E
Sbjct: 408 RRQARLQKEQEEQERVEKEEQDRLEREELKRKAEE-ERLRLEEEARKQEEERKRQE--EE 464
Query: 118 QVHQPLLEEQCSIDEPL--FEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEE 175
+ Q E++ + +E E++ + Q +E+ K + + +K+ + KA+E
Sbjct: 465 KKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMI------EKQKEAAETKAREV 518
Query: 176 YEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNK-----KTKKGQPNLNVQM 230
EQ++ +R + E+ + ER KK+ E+ K K + KK P + VQ
Sbjct: 519 AEQMRLEREQIMLQIEQERLER-------KKRIDEIMKRTRKSDVPPQVKKEDPKVGVQP 571
Query: 231 EYLLQK 236
++K
Sbjct: 572 AVCVEK 577
Score = 34.3 bits (77), Expect = 0.099
Identities = 24/103 (23%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
Query: 138 QCSFDQPQPEEQCIKTVNSFTIPKKN-KKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQE 196
Q + Q E++ ++ + ++ K+K ++ + E E + + K+QE E++KQE
Sbjct: 410 QARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQE 469
Query: 197 REEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
EE ++ ++ K + + L K K+ Q Q + +++K +E
Sbjct: 470 GEEKRKAGEEAKRKAEEELLLKEKQEQEK---QEKAMIEKQKE 509
Score = 31.2 bits (69), Expect = 0.84
Identities = 22/101 (21%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Query: 143 QPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQER----E 198
+PQ E +K+ + K+ +++ A E +QI K+ + ++E++ +ER E
Sbjct: 41 RPQGMEGFLKSDERQRLAKERREEREKCLAARE-QQILEKQKRARLQYEKQMEERWRKLE 99
Query: 199 EAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQE 239
E +++ +K+ V + +K ++ + L M L++ Q+
Sbjct: 100 EQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQ 140
Score = 29.3 bits (64), Expect = 3.2
Identities = 26/143 (18%), Positives = 68/143 (47%), Gaps = 10/143 (6%)
Query: 98 LAEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSF 157
LAE+ R + ++ + E+V + EEQ ++ + + ++ + EE+ K
Sbjct: 404 LAEKRRQARLQKEQEE--QERVEK---EEQDRLEREELKRKAEEERLRLEEEARKQEEER 458
Query: 158 TIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNK 217
++ KKK ++ ++ E+ + K + E+++QE++E K+K +
Sbjct: 459 KRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQK-----EAAET 513
Query: 218 KTKKGQPNLNVQMEYLLQKIQEK 240
K ++ + ++ E ++ +I+++
Sbjct: 514 KAREVAEQMRLEREQIMLQIEQE 536
>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
sapiens]
Length = 529
Score = 40.4 bits (93), Expect = 0.001
Identities = 54/225 (24%), Positives = 94/225 (41%), Gaps = 43/225 (19%)
Query: 33 RQKTWRPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDN 92
RQ W Q FV R K K + ++ + + + +T E Q +++
Sbjct: 246 RQGAWDDYDHQNFV---------KVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQK 296
Query: 93 LKHLYLAEEERHRKQARKVDHPLSEQVHQPL--LEEQCSIDEPLFEDQCSFDQPQPEEQC 150
+LA EER +K++ ++ +Q + + L+E+ LF ++ +Q Q EEQ
Sbjct: 297 ----FLALEER-KKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQ- 350
Query: 151 IKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYK----- 205
KK K K Q+ E + K+E E+ K+ ++E QRQ+K
Sbjct: 351 ---------RKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLL 401
Query: 206 ------KKKMEVF----KILNKKTKKGQPNLNVQMEYLLQKIQEK 240
KK+ E F K + +K +K + N E + + QE+
Sbjct: 402 ESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADE--ISRFQER 444
>gi|157785548 PAS domain containing 1 [Homo sapiens]
Length = 773
Score = 40.4 bits (93), Expect = 0.001
Identities = 45/210 (21%), Positives = 92/210 (43%), Gaps = 12/210 (5%)
Query: 38 RPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKE--KKAQTSLESQFT--DRYPDNL 93
+P P + V Q +KLK Q + L + + Q +LE + P+ L
Sbjct: 357 QPLQPSSPVAYDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTL 416
Query: 94 KHLYLAEEERHRKQARKVDHPLSEQVHQPL---LEEQCSIDEPLFEDQCSFDQPQPEEQC 150
+H+ + + + +K + QV +PL + +C L + + Q E C
Sbjct: 417 RHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQ--EPC 474
Query: 151 IKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKME 210
+ + ++ K ++ +E+ +Q++ +R +KQ+ + K++ +E + Q KKK E
Sbjct: 475 VAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQE 534
Query: 211 VFKILNKKTKKGQPNLNVQMEYLLQKIQEK 240
+ +K KK Q Q + L ++ +E+
Sbjct: 535 QRR---QKKKKLQERKKWQGQMLQKEPEEE 561
>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
sapiens]
Length = 446
Score = 40.4 bits (93), Expect = 0.001
Identities = 54/225 (24%), Positives = 94/225 (41%), Gaps = 43/225 (19%)
Query: 33 RQKTWRPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDN 92
RQ W Q FV R K K + ++ + + + +T E Q +++
Sbjct: 163 RQGAWDDYDHQNFV---------KVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQK 213
Query: 93 LKHLYLAEEERHRKQARKVDHPLSEQVHQPL--LEEQCSIDEPLFEDQCSFDQPQPEEQC 150
+LA EER +K++ ++ +Q + + L+E+ LF ++ +Q Q EEQ
Sbjct: 214 ----FLALEER-KKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQ- 267
Query: 151 IKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYK----- 205
KK K K Q+ E + K+E E+ K+ ++E QRQ+K
Sbjct: 268 ---------RKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLL 318
Query: 206 ------KKKMEVF----KILNKKTKKGQPNLNVQMEYLLQKIQEK 240
KK+ E F K + +K +K + N E + + QE+
Sbjct: 319 ESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADE--ISRFQER 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,529,756
Number of Sequences: 37866
Number of extensions: 461795
Number of successful extensions: 7067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 306
Number of HSP's successfully gapped in prelim test: 484
Number of HSP's that attempted gapping in prelim test: 3651
Number of HSP's gapped (non-prelim): 2506
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.