Search of human proteins with 156105701

Search of human proteins with 156105701

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo
sapiens]
         (1112 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo ...  2243   0.0  
gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo ...  2224   0.0  
gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo sa...   209   9e-54
gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sa...   209   1e-53
gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]             71   7e-12
gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens]      69   2e-11
gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens]      55   5e-07
gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]         54   6e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    38   0.061
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho...    38   0.061
gi|125656165 THO complex 2 [Homo sapiens]                              37   0.10 
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    37   0.10 
gi|16445438 bromodomain and WD repeat domain containing 1 isofor...    37   0.10 
gi|16445436 bromodomain and WD repeat domain containing 1 isofor...    37   0.10 
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    37   0.14 
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap...    36   0.18 
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             34   0.67 
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    34   0.67 
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    34   0.67 
gi|5174715 transcription factor-like 1 [Homo sapiens]                  34   0.88 
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]     34   0.88 
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]     34   0.88 
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                33   1.2  
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 33   1.2  
gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo s...    33   1.2  
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s...    33   1.2  
gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo s...    33   1.2  
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s...    33   1.2  
gi|33942066 SUMO/sentrin specific peptidase family member 8 [Hom...    33   1.2  
gi|9910430 matrix, extracellular phosphoglycoprotein with ASARM ...    33   1.5  

>gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo
            sapiens]
          Length = 1112

 Score = 2243 bits (5813), Expect = 0.0
 Identities = 1112/1112 (100%), Positives = 1112/1112 (100%)

Query: 1    MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDE 60
            MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDE
Sbjct: 1    MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDE 60

Query: 61   DSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSEN 120
            DSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSEN
Sbjct: 61   DSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSEN 120

Query: 121  TQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRL 180
            TQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRL
Sbjct: 121  TQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRL 180

Query: 181  QGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQ 240
            QGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQ
Sbjct: 181  QGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQ 240

Query: 241  AITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQ 300
            AITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQ
Sbjct: 241  AITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQ 300

Query: 301  TNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSAC 360
            TNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSAC
Sbjct: 301  TNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSAC 360

Query: 361  SSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR 420
            SSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR
Sbjct: 361  SSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR 420

Query: 421  RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHD 480
            RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHD
Sbjct: 421  RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHD 480

Query: 481  PVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLT 540
            PVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLT
Sbjct: 481  PVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLT 540

Query: 541  NLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYE 600
            NLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYE
Sbjct: 541  NLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYE 600

Query: 601  ESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPP 660
            ESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPP
Sbjct: 601  ESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPP 660

Query: 661  PAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQ 720
            PAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQ
Sbjct: 661  PAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQ 720

Query: 721  RERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPK 780
            RERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPK
Sbjct: 721  RERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPK 780

Query: 781  YEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN 840
            YEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN
Sbjct: 781  YEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN 840

Query: 841  PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLS 900
            PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLS
Sbjct: 841  PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLS 900

Query: 901  STHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ 960
            STHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ
Sbjct: 901  STHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ 960

Query: 961  WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1020
            WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK
Sbjct: 961  WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1020

Query: 1021 VPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQE 1080
            VPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQE
Sbjct: 1021 VPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQE 1080

Query: 1081 DQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD 1112
            DQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD
Sbjct: 1081 DQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD 1112


>gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo
            sapiens]
          Length = 1105

 Score = 2224 bits (5762), Expect = 0.0
 Identities = 1105/1112 (99%), Positives = 1105/1112 (99%), Gaps = 7/1112 (0%)

Query: 1    MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDE 60
            MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDE
Sbjct: 1    MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDE 60

Query: 61   DSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSEN 120
            DSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSEN
Sbjct: 61   DSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSEN 120

Query: 121  TQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRL 180
            TQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQ       RKEYPPHVQKVEINPVRLSRL
Sbjct: 121  TQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQ-------RKEYPPHVQKVEINPVRLSRL 173

Query: 181  QGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQ 240
            QGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQ
Sbjct: 174  QGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQ 233

Query: 241  AITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQ 300
            AITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQ
Sbjct: 234  AITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQ 293

Query: 301  TNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSAC 360
            TNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSAC
Sbjct: 294  TNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSAC 353

Query: 361  SSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR 420
            SSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR
Sbjct: 354  SSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR 413

Query: 421  RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHD 480
            RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHD
Sbjct: 414  RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHD 473

Query: 481  PVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLT 540
            PVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLT
Sbjct: 474  PVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLT 533

Query: 541  NLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYE 600
            NLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYE
Sbjct: 534  NLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYE 593

Query: 601  ESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPP 660
            ESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPP
Sbjct: 594  ESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPP 653

Query: 661  PAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQ 720
            PAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQ
Sbjct: 654  PAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQ 713

Query: 721  RERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPK 780
            RERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPK
Sbjct: 714  RERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPK 773

Query: 781  YEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN 840
            YEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN
Sbjct: 774  YEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN 833

Query: 841  PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLS 900
            PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLS
Sbjct: 834  PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLS 893

Query: 901  STHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ 960
            STHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ
Sbjct: 894  STHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ 953

Query: 961  WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1020
            WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK
Sbjct: 954  WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1013

Query: 1021 VPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQE 1080
            VPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQE
Sbjct: 1014 VPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQE 1073

Query: 1081 DQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD 1112
            DQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD
Sbjct: 1074 DQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD 1105


>gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo
           sapiens]
          Length = 1050

 Score =  209 bits (533), Expect = 9e-54
 Identities = 232/890 (26%), Positives = 369/890 (41%), Gaps = 171/890 (19%)

Query: 40  EESEGDTDKDGTNLLSVDEDEDSETSKG----------KKLNRRSEIVANSSGEFILKTY 89
           E S  DTD   +  LS   D   E+ +           ++ ++RS+ V ++S +      
Sbjct: 187 EGSLSDTDNLQSEQLSSSSDGSLESYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTAHNK 246

Query: 90  VRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKT 149
            +R K +          G+++L ++ +  +    +  C       R     ++   V  T
Sbjct: 247 EKRRKDD----------GISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELT 296

Query: 150 AAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKR 209
                  R+ R   P       ++       +  E+  K+ ++S    E E   K  +  
Sbjct: 297 LISRKTKRRLRNNLPDSQYCTSLD-------KSTEQTKKQEDDSTISTEFE---KPSENY 346

Query: 210 HCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTG 269
           H     P    +  +K   T L  L     Q +TL+ +T               KS + G
Sbjct: 347 HQDPKLPEEITTKPTKSDFTKLSSLNS---QELTLSNAT---------------KSASAG 388

Query: 270 LTTKKFYGNN-VEKVPIDIIVNCDDSKHTYLQTNGKVILPGAKIPKITNLKERKTSLSDL 328
            TT+    +N ++ V I  +V  D+++   L T  K IL G          E   SL   
Sbjct: 389 STTETVENSNSIDIVGISSLVEKDENE---LNTIEKPILRGHN--------EGNQSLISA 437

Query: 329 NDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEA-ALNENTCRAERELRS 387
            +PI++SSD++               P +   S       K +    NEN   +E  L  
Sbjct: 438 -EPIVVSSDEEG--------------PVEHKSSEILKLQSKQDRETTNENESTSESALLE 482

Query: 388 IP----EDSELNTVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSV 443
           +P    E  ++++   P    M++               + S  P + + L     F SV
Sbjct: 483 LPLITCESVQMSSELCPYNPVMEN---------------ISSIMPSNEMDLQLDFIFTSV 527

Query: 444 ILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDL-------TKCEW 496
                   +G +       V     +IKI   +   + + ++++T+ L       +K + 
Sbjct: 528 Y-------IGKIKGASKGCVTITKKYIKIPF-QVSLNEISLLVDTTHLKRFGLWKSKDDN 579

Query: 497 CNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLD 556
            + R   ++F        Q++  QL+ +           V    +   ++I L   N + 
Sbjct: 580 HSKRSHAILFFWVSSDYLQEIQTQLEHS-----------VLSQQSKSSEFIFLELHNPVS 628

Query: 557 PPANMVFESIINEIGIKNN----------ISNF--FAKIPFEEANGRLVACTRTYEESIK 604
               +  + I+ EI I +           +  F  F  +  +E++     C  T      
Sbjct: 629 QREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNLSSKESSFIHYYCVSTCSFPA- 687

Query: 605 GSCGQKENKIKTVSFESKIQLRSKQEFQFFD---------------EEEETGENHTIFIG 649
           G    +E K+K+VS  S     +K  + F                 +EE     HT   G
Sbjct: 688 GVAVAEEMKLKSVSQPSNTDA-AKPTYTFLQKQSSGCYSLSITSNPDEEWREVRHT---G 743

Query: 650 PVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHI 709
            V+KLIVYPPPP KGG+ VTNEDL CL EGEFLNDVIIDFYLKYL+LEK   E  +R HI
Sbjct: 744 LVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHI 803

Query: 710 FSSFFYKRLNQRERR-NHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFL 768
           FSSFFYK L ++E     +  NLS+ Q+RH RV+TWTRH++IF KD+IFVP+NE++HW+L
Sbjct: 804 FSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYL 863

Query: 769 AVVCFPGLEKPKYEPNPH-----------YHENAVIQKCSTVEDSCISSSASEMESCSQN 817
           AV+CFP LE+  YE  P             ++N  I        S +S SA + +S   N
Sbjct: 864 AVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDN-DLRTTSTLSLSAEDSQSTESN 922

Query: 818 SSAKPVIKKMLNKKHCIAVIDS-NPGQEESDPRYKRNICSVKYSVKKINH 866
            S    + K + K+ CI ++DS      ++  +  R    V++ VK   H
Sbjct: 923 MS----VPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTH 968



 Score =  149 bits (376), Expect = 1e-35
 Identities = 75/135 (55%), Positives = 99/135 (73%), Gaps = 1/135 (0%)

Query: 950  ADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSF 1009
            A+D+ S+E     +   +CK+PCIL++DSL+  S  N V+ LREYLEVEWEVK  + R F
Sbjct: 913  AEDSQSTE-SNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQF 971

Query: 1010 SKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKRE 1069
            SK  M    PKVP+Q+N SDCGVY+LQYVESFF++PI++FELP++L  WFP   ++TKRE
Sbjct: 972  SKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKRE 1031

Query: 1070 EIRNIILKLQEDQSK 1084
            +IR +ILKL   Q K
Sbjct: 1032 DIRELILKLHLQQQK 1046


>gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo
           sapiens]
          Length = 985

 Score =  209 bits (532), Expect = 1e-53
 Identities = 207/731 (28%), Positives = 317/731 (43%), Gaps = 142/731 (19%)

Query: 189 KTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNEST 248
           K +E +S +  E + K  +  H     P    +  +K   T L  L     Q +TL+ +T
Sbjct: 262 KKQEDDSTISTEFE-KPSENYHQDPKLPEEITTKPTKSDFTKLSSLNS---QELTLSNAT 317

Query: 249 GPLLRTSIHQNSGGQKSQNTGLTTKKFYGNN-VEKVPIDIIVNCDDSKHTYLQTNGKVIL 307
                          KS + G TT+    +N ++ V I  +V  D+++   L T  K IL
Sbjct: 318 ---------------KSASAGSTTETVENSNSIDIVGISSLVEKDENE---LNTIEKPIL 359

Query: 308 PGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPST 367
            G          E   SL    +PI++SSD++               P +   S      
Sbjct: 360 RGHN--------EGNQSLISA-EPIVVSSDEEG--------------PVEHKSSEILKLQ 396

Query: 368 GKVEA-ALNENTCRAERELRSIP----EDSELNTVTLPRKARMKDQFGNSIINTPLKRRK 422
            K +    NEN   +E  L  +P    E  ++++   P    M++               
Sbjct: 397 SKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMEN--------------- 441

Query: 423 VFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPV 482
           + S  P + + L     F SV        +G +       V     +IKI   +   + +
Sbjct: 442 ISSIMPSNEMDLQLDFIFTSVY-------IGKIKGASKGCVTITKKYIKIPF-QVSLNEI 493

Query: 483 EIILNTSDL-------TKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKG 535
            ++++T+ L       +K +  + R   ++F        Q++  QL+ +           
Sbjct: 494 SLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEHS----------- 542

Query: 536 VNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNN----------ISNF--FAKI 583
           V    +   ++I L   N +     +  + I+ EI I +           +  F  F  +
Sbjct: 543 VLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNL 602

Query: 584 PFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFD-------- 635
             +E++     C  T      G    +E K+K+VS  S     +K  + F          
Sbjct: 603 SSKESSFIHYYCVSTCSFPA-GVAVAEEMKLKSVSQPSNTDA-AKPTYTFLQKQSSGCYS 660

Query: 636 -------EEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIID 688
                  +EE     HT   G V+KLIVYPPPP KGG+ VTNEDL CL EGEFLNDVIID
Sbjct: 661 LSITSNPDEEWREVRHT---GLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIID 717

Query: 689 FYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERR-NHETTNLSIQQKRHGRVKTWTRH 747
           FYLKYL+LEK   E  +R HIFSSFFYK L ++E     +  NLS+ Q+RH RV+TWTRH
Sbjct: 718 FYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRH 777

Query: 748 VDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPH-----------YHENAVIQKC 796
           ++IF KD+IFVP+NE++HW+LAV+CFP LE+  YE  P             ++N  I   
Sbjct: 778 INIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDN- 836

Query: 797 STVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDS-NPGQEESDPRYKRNIC 855
                S +S SA + +S   N S    + K + K+ CI ++DS      ++  +  R   
Sbjct: 837 DLRTTSTLSLSAEDSQSTESNMS----VPKKMCKRPCILILDSLKAASVQNTVQNLREYL 892

Query: 856 SVKYSVKKINH 866
            V++ VK   H
Sbjct: 893 EVEWEVKLKTH 903



 Score =  149 bits (376), Expect = 1e-35
 Identities = 75/135 (55%), Positives = 99/135 (73%), Gaps = 1/135 (0%)

Query: 950  ADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSF 1009
            A+D+ S+E     +   +CK+PCIL++DSL+  S  N V+ LREYLEVEWEVK  + R F
Sbjct: 848  AEDSQSTE-SNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQF 906

Query: 1010 SKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKRE 1069
            SK  M    PKVP+Q+N SDCGVY+LQYVESFF++PI++FELP++L  WFP   ++TKRE
Sbjct: 907  SKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKRE 966

Query: 1070 EIRNIILKLQEDQSK 1084
            +IR +ILKL   Q K
Sbjct: 967  DIRELILKLHLQQQK 981


>gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]
          Length = 643

 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 17/169 (10%)

Query: 666 ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRN 725
           +++T +D+  LN   +LND II+FY+  L +E+ K++    +H F++FF+ +L       
Sbjct: 450 LTITRKDIQTLNHLNWLNDEIINFYMNML-MERSKEKGLPSVHAFNTFFFTKL------- 501

Query: 726 HETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNP 785
                   +   +  VK WT+ VD+F  D + VP++   HW LAVV F       Y+   
Sbjct: 502 --------KTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMG 553

Query: 786 HYHENAVIQKCSTVEDSCISSSASEMESCS-QNSSAKPVIKKMLNKKHC 833
             +  A       ++   I     E ++   Q  S K  I + +N   C
Sbjct: 554 GINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGSDC 602



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 961  WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1020
            W L     ++  I   DS+ G + +   +IL +YL+ E   KK  +   +   +     +
Sbjct: 534  WCLAVVDFRKKNITYYDSMGGIN-NEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQ 592

Query: 1021 VPQQNNFSDCGVYVLQYVESFFENPILSF 1049
            +PQQ N SDCG++  +Y +   ++  ++F
Sbjct: 593  IPQQMNGSDCGMFACKYADCITKDRPINF 621


>gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens]
          Length = 589

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 16/106 (15%)

Query: 666 ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRN 725
           + +T  D+  L    +LND +I+FY+  LV E+ KK+    +H+FS+FFY +L       
Sbjct: 395 LRITRGDIQTLKNYHWLNDEVINFYMNLLV-ERNKKQGYPALHVFSTFFYPKL------- 446

Query: 726 HETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVV 771
                   +   +  VK WT+ V++FE++ I VP++   HW L V+
Sbjct: 447 --------KSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVI 484



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 2/90 (2%)

Query: 961  WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNP- 1019
            W L     ++ C+  +DS+ G     + +IL +YL+ E + K+ S  +  +       P 
Sbjct: 479  WSLVVIDLRKKCLKYLDSM-GQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPH 537

Query: 1020 KVPQQNNFSDCGVYVLQYVESFFENPILSF 1049
            ++PQQ N SDCG++  +Y +    +  ++F
Sbjct: 538  EIPQQLNGSDCGMFTCKYADYISRDKPITF 567


>gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens]
          Length = 574

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 20/104 (19%)

Query: 668 VTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHE 727
           +T +DL  L    +LND +++ Y   LV++ +     +++H F+SFFY +L         
Sbjct: 388 LTMDDLGTLYGQNWLNDQVMNMYGD-LVMDTVP----EKVHFFNSFFYDKL--------- 433

Query: 728 TTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVV 771
                 + K +  VK WT++VDIF K+ + +P++   HW L  V
Sbjct: 434 ------RTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISV 471



 Score = 34.3 bits (77), Expect = 0.67
 Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 961  WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1020
            W L     ++  I   DS R  +R    K + +YL+ E  VKK  +  F +         
Sbjct: 466  WSLISVDVRRRTITYFDSQRTLNR-RCPKHIAKYLQAE-AVKK-DRLDFHQGWKGYFKMN 522

Query: 1021 VPQQNNFSDCGVYVLQYVESFFENPILSF 1049
            V +QNN SDCG +VLQY +    +   SF
Sbjct: 523  VARQNNDSDCGAFVLQYCKHLALSQPFSF 551


>gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]
          Length = 755

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 20/101 (19%)

Query: 671 EDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTN 730
           +DL  L+   +LND +I+ Y + L+++ +     D++H F+SFF+++L            
Sbjct: 572 DDLATLDGQNWLNDQVINMYGE-LIMDAVP----DKVHFFNSFFHRQL------------ 614

Query: 731 LSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVV 771
                K +  VK WT+ VD+F+K  + +P++   HW L  V
Sbjct: 615 ---VTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITV 652



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)

Query: 988  VKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQY 1037
            V+ +R+YL  E   ++ ++  F +         +PQQ N SDCGV+VLQY
Sbjct: 673  VENIRKYLLTE--AREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 37.7 bits (86), Expect = 0.061
 Identities = 37/161 (22%), Positives = 65/161 (40%), Gaps = 4/161 (2%)

Query: 797 STVEDSCISSSASEMESCSQNSS--AKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNI 854
           S+  DS  S+S+S+ +S   +SS  +        N        DS+   + SD    ++ 
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625

Query: 855 CSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLN 914
            S   S    + + S++ + N  +S+    +  + + +   + S SS       S    N
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 915 YSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCS 955
            SD S  +      E  D S+  D+  DSSD    ++ N S
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDS--DSSDSSDSSNSNSS 724



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 37/165 (22%), Positives = 64/165 (38%), Gaps = 6/165 (3%)

Query: 797 STVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNICS 856
           S+  +S  S S S+ +S   NSS         +  +     DS+   + SD     +  +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 857 VKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYS 916
              S    + +++ +E  +  +S+    +D + S N   ++S SS       S    + S
Sbjct: 686 SSDSSDS-SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744

Query: 917 DESPEAGKMLEDELVDFSEDQDNQ-----DDSSDDGFLADDNCSS 956
           D S  +      +  D S   D+       DSSD    +D N SS
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 5/166 (3%)

Query: 797  STVEDSCISSSASEME--SCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNI 854
            S   DS  SS++S+    S S NSS         N        DS+   + SD     + 
Sbjct: 918  SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977

Query: 855  CSVKYSVKKINHTASENEEFN--KGESTSQKVADRTKSENGLQNESLS-STHHTDGLSKI 911
             S   S    +  +S++ + +     S S   +D + S N   + + S S++ +D     
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 912  RLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSE 957
              + S +S ++    +      S D  +  DSSD    +D + SSE
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 37/163 (22%), Positives = 62/163 (38%), Gaps = 10/163 (6%)

Query: 797  STVEDSCISSSASEME--SCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNI 854
            S   DS  SS +S+    S S NSS         N        DS+   + SD       
Sbjct: 995  SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD------- 1047

Query: 855  CSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLN 914
             S   S    +  +S++ + +    +S        SE+   ++S +S+  +D       +
Sbjct: 1048 -SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106

Query: 915  YSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSE 957
             S +S ++    +      S D  +  DSSD    +D + SSE
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 3/96 (3%)

Query: 865 NHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSD-ESPEAG 923
           N ++  +  +N  ES        +K      ++S S T+++D          D +  ++G
Sbjct: 484 NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543

Query: 924 KMLEDELVDFSEDQDNQDDSSD--DGFLADDNCSSE 957
           K   D     S D  N  DSSD  D   +D N SS+
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD 579



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 42/173 (24%), Positives = 67/173 (38%), Gaps = 16/173 (9%)

Query: 797 STVEDSCISSSASEMESC-SQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNIC 855
           S   DS  SS +S+ +S  S +SS         N        DS+ G +        +  
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863

Query: 856 SVKYSVKKINHTASE-------NEEFNKGEST-SQKVADRTKSENGLQNESLSSTHHTDG 907
           S   S    +  +S+       NE  N  +S+ S   +D   S++   ++S  S++ +D 
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD- 922

Query: 908 LSKIRLNYSDESPEAGKMLEDELVDFSE-----DQDNQDDSSDDGFLADDNCS 955
            S    N SD S  +      +  D S+     D  N  DSS+    +D N S
Sbjct: 923 -SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 35/161 (21%), Positives = 61/161 (37%), Gaps = 24/161 (14%)

Query: 797  STVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNICS 856
            S   DS  SS +S+    S +S++                 DS+   + SD     N   
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSS----------------DSSDSSDSSDSSDSSNSSD 1143

Query: 857  VKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYS 916
               S +  + + S +   +   S S   +D + S N   ++S  S+  +D       + S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS--SDSSDSSDSSDSSDSSDSSDS 1201

Query: 917  DESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSE 957
             +S ++    +      S D  +  DSSD    +D N SS+
Sbjct: 1202 SDSSDSSDSSD------SSDSSDSSDSSDSSDSSDSNESSD 1236



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 12/110 (10%)

Query: 863 KINHTASENEEFNKG------ESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNY- 915
           K+ H+ + ++  + G      +  S +  D   S+    N+  +S    +  S+   +Y 
Sbjct: 435 KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN 494

Query: 916 SDESPEAG-----KMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQ 960
           SDES + G     K  ED+  D + D +N D + +     DDN  S+ G+
Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544


>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
            sapiens]
          Length = 3549

 Score = 37.7 bits (86), Expect = 0.061
 Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 9/132 (6%)

Query: 109  NMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRK-----ERKEY 163
            N+  +N K SE  +N      TV H    HH       VKT  +  LD         K  
Sbjct: 3058 NVHVSNNKNSEQKENKIAKEKTVQHQVAAHHEATVRSHVKTHQEIKLDDSNIPPPSLKTR 3117

Query: 164  PPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKR--HCSTYQPTPPLS 221
            PP    + I           +  + ++ + +S VEP  +R + QK   H +   P+PP S
Sbjct: 3118 PPSPTFITIESTARRTENPTKNELSQSPKKDSYVEPPPRRPMSQKSEIHRANTSPSPPRS 3177

Query: 222  PASKKCLTHLED 233
             + +  L  L+D
Sbjct: 3178 RSEQ--LVRLKD 3187



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 36/189 (19%), Positives = 75/189 (39%), Gaps = 4/189 (2%)

Query: 42  SEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTL 101
           S GD      N++   E         K   +  + + +S   F    Y  +N+SE  + +
Sbjct: 231 SRGDCRSFSANMMEESEMCAVPGGLAKVKKQFEDEITSSRNTFAQYQYQHQNRSEQ-EAI 289

Query: 102 KGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRF-HHAHAQIPVVKTAAQSSLDRKER 160
             + +G +  S  ++++ N Q  S      VHG     H       V  A+Q     +E 
Sbjct: 290 HSSQVGTSRSS--QEMARNEQEGSKVQKIDVHGTEMVSHLEKHTEEVNQASQFHQYVQET 347

Query: 161 KEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPL 220
               P  +++     +L + Q  +   +K   S+ ++    K+   +  +  T++P+  +
Sbjct: 348 VIDTPEDEEIPKVSTKLLKEQFEKSAQEKILYSDKEMTTPAKQIKTESEYEETFKPSSVV 407

Query: 221 SPASKKCLT 229
           S +S  C++
Sbjct: 408 STSSTSCVS 416


>gi|125656165 THO complex 2 [Homo sapiens]
          Length = 1593

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 53/255 (20%), Positives = 92/255 (36%), Gaps = 17/255 (6%)

Query: 844  EESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENG--LQNESLSS 901
            EE+D   +R+ C VK   K  + T   N       S S K       E G   + E    
Sbjct: 1225 EETDKSRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEK 1284

Query: 902  THHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQW 961
            T  T   +++      E P+  +  +DE    ++++  + D   + F  ++    E    
Sbjct: 1285 TPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDE---- 1340

Query: 962  HLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKR----SFSKDVMKGS 1017
              K T+         +  R    S    I +E    E  VK G K     S    V +  
Sbjct: 1341 KFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKE-NVKGGEKTPVSGSLKSPVPRSD 1399

Query: 1018 NPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLA----NWFPPPRMRTKREEIRN 1073
             P+  ++        +      S  ++ ++  EL  + A    N  PPP  ++K  E+  
Sbjct: 1400 IPEPEREQKRRKIDTHPSPSHSSTVKDSLI--ELKESSAKLYINHTPPPLSKSKEREMDK 1457

Query: 1074 IILKLQEDQSKEKRK 1088
              L    ++S+E+ K
Sbjct: 1458 KDLDKSRERSREREK 1472


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 20/168 (11%)

Query: 800  EDSCISSSASEMESCSQNSSAKPVIKKM-----LNKKHCIAVIDSNPGQEESDPRYKRNI 854
            EDS I +S    +  S ++   P+ KK+     +  +  +   +S  G+ E+    + + 
Sbjct: 1836 EDSTIEAS----DQVSDDTVEMPLPKKLKSVTPVGTEEEVMAEESTDGEVETQVYNQDSQ 1891

Query: 855  CSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSK---I 911
             S+   V + ++T  E+ E      TSQ +         LQ++  ++T   DG  K   +
Sbjct: 1892 DSIGEGVTQGDYTPMEDSE-----ETSQSLQIDL---GPLQSDQQTTTSSQDGQGKGDDV 1943

Query: 912  RLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIG 959
             +  SD+  E     + E  D+ ED+++ DD  DD  + D+   S  G
Sbjct: 1944 IVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTGMGDEGEDSNEG 1991


>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
            [Homo sapiens]
          Length = 2269

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 38/171 (22%), Positives = 71/171 (41%), Gaps = 17/171 (9%)

Query: 797  STVEDSCISSSASEMESCSQNSSAKPVIKKM-----LNKKHCIAVIDSNPGQEESDPRYK 851
            S VEDS  +S +S   S S+ S      ++      L++   + V  +   Q ++ P   
Sbjct: 1530 SEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSL 1589

Query: 852  RNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKI 911
             N C  K + K++  + S+N     GE    +  +  K    L+  +  + +    +S +
Sbjct: 1590 ANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKV---LRKCAAVAANKIKLMSDV 1646

Query: 912  RLNYSDESPEAGKML---------EDELVDFSEDQDNQDDSSDDGFLADDN 953
              N S ES  +G+ L           +L+  SED+ +     ++  L D+N
Sbjct: 1647 EENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDEN 1697


>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
            [Homo sapiens]
          Length = 2320

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 38/171 (22%), Positives = 71/171 (41%), Gaps = 17/171 (9%)

Query: 797  STVEDSCISSSASEMESCSQNSSAKPVIKKM-----LNKKHCIAVIDSNPGQEESDPRYK 851
            S VEDS  +S +S   S S+ S      ++      L++   + V  +   Q ++ P   
Sbjct: 1530 SEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSL 1589

Query: 852  RNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKI 911
             N C  K + K++  + S+N     GE    +  +  K    L+  +  + +    +S +
Sbjct: 1590 ANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKV---LRKCAAVAANKIKLMSDV 1646

Query: 912  RLNYSDESPEAGKML---------EDELVDFSEDQDNQDDSSDDGFLADDN 953
              N S ES  +G+ L           +L+  SED+ +     ++  L D+N
Sbjct: 1647 EENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDEN 1697


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 32/168 (19%)

Query: 40  EESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFK 99
           ++++G   K        +EDED+     KK+  RS I  NSSGE         ++S+ F 
Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNS----KKIKERSRI--NSSGE-------SGDESDEF- 193

Query: 100 TLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKE 159
                   L      KK  +N    ++ SG       F         +KT AQ   ++KE
Sbjct: 194 --------LQSRKGQKKNQKNKPGPNIESGNEDDDASFK--------IKTVAQKKAEKKE 237

Query: 160 RKEYPPHVQKVEINPVR-LSRLQGVERIMKKTEESESQVEPE-IKRKV 205
           R+      +K ++  ++    L+  ++   K +ES+ + E E +K KV
Sbjct: 238 RERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV 285


>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 1827

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 27/153 (17%)

Query: 186 IMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDL------QRNCR 239
           ++K  +E E+Q + +           +   P+PP SPAS++ +T  EDL      + + +
Sbjct: 105 VLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEDLLTASKMEFHDQ 164

Query: 240 QAITLN--ESTGPLLRTSIHQNSGGQKSQNTGL-----TTKKF------YGNNVEKVPI- 285
           Q +T +  E +    + S  Q+  G+  ++  L     TTK +       G   EK P+ 
Sbjct: 165 QELTPSTAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDMQGTEEEKAPLA 224

Query: 286 ----DIIVNCDDSKHTYLQTNGKVILPGAKIPK 314
                ++ + +D K    +T   +++PG  +PK
Sbjct: 225 LFGHTLVASLEDMKQ---KTEPSLVVPGIDLPK 254


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 34.3 bits (77), Expect = 0.67
 Identities = 43/192 (22%), Positives = 79/192 (41%), Gaps = 25/192 (13%)

Query: 40   EESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSE-IVANSSGEFILKTYVRRNKSESF 98
            +  E  +D D +   S DED D E  + +     S+  + N +G  ++ +          
Sbjct: 869  QRPEPQSDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSS---------- 918

Query: 99   KTLKGNPIGLNMLSNNKKLSENTQNTSLCS---GTVVHGRRFHHAHAQIPVVKTAAQSSL 155
              LK NP+ L  L +   +     + + C+   GT V G   +  H     +K   +S+L
Sbjct: 919  -PLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRH-----IKAMHESAL 972

Query: 156  --DRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCST 213
              ++++R+E      +   +P   S+     R  +  + +  QV   +   V+      T
Sbjct: 973  LEEQRQRQEQIDLECRSSTSPCGTSK--SPNREWEVLQPAPHQVITNLPEGVRLPTTRPT 1030

Query: 214  YQPTPPLSPASK 225
             +P PPL P+SK
Sbjct: 1031 -RPPPPLIPSSK 1041


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 34.3 bits (77), Expect = 0.67
 Identities = 34/155 (21%), Positives = 64/155 (41%), Gaps = 18/155 (11%)

Query: 809  SEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQE---------ESDPRYKRNICSVK- 858
            SE +S S+ S       ++L  +H + V D   G+E         E   R +R + S   
Sbjct: 1284 SESDSDSEESKKPRYRHRLL--RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDS 1341

Query: 859  ----YSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHT--DGLSKIR 912
                +    ++   SE+E+  +  + S K A+  +++   + +          D  S+ +
Sbjct: 1342 EDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENK 1401

Query: 913  LNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDG 947
             N  +E  E  +  E+E  +  E++D  DDS   G
Sbjct: 1402 SNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1436


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 34.3 bits (77), Expect = 0.67
 Identities = 34/155 (21%), Positives = 64/155 (41%), Gaps = 18/155 (11%)

Query: 809  SEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQE---------ESDPRYKRNICSVK- 858
            SE +S S+ S       ++L  +H + V D   G+E         E   R +R + S   
Sbjct: 1322 SESDSDSEESKKPRYRHRLL--RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDS 1379

Query: 859  ----YSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHT--DGLSKIR 912
                +    ++   SE+E+  +  + S K A+  +++   + +          D  S+ +
Sbjct: 1380 EDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENK 1439

Query: 913  LNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDG 947
             N  +E  E  +  E+E  +  E++D  DDS   G
Sbjct: 1440 SNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1474


>gi|5174715 transcription factor-like 1 [Homo sapiens]
          Length = 364

 Score = 33.9 bits (76), Expect = 0.88
 Identities = 48/233 (20%), Positives = 93/233 (39%), Gaps = 21/233 (9%)

Query: 28  GGFKNNWSFDHEEESEGDTDKDGTNLLSVDE-DEDSETSKGKKLNRRSEIVANSSGEFIL 86
           GGF      D  +  + DT+ +  +   +DE DE S   + ++  R+  +V  +  E + 
Sbjct: 35  GGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLK 94

Query: 87  KTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPV 146
               R+  + +  + K       +L    +   +    S+   T  H R+       + V
Sbjct: 95  SLRPRKVNTPAGSSQKARE-EKALLPLELQDDGSDSRKSMRQSTAEHTRQ-----TFLRV 148

Query: 147 VKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQ 206
            +   QS      R+   PH ++       L   +  E +  ++ E+  ++E + K++V 
Sbjct: 149 QERQGQS------RRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVH 202

Query: 207 QKRHC-----STYQPTPPL--SPASKKCLTHLEDLQ-RNCRQAITLNESTGPL 251
           +KR C     + +  T PL   P  K+    +E L       A+T +  TGP+
Sbjct: 203 KKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPAPSVSALTPHAGTGPV 255


>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
          Length = 1226

 Score = 33.9 bits (76), Expect = 0.88
 Identities = 59/252 (23%), Positives = 102/252 (40%), Gaps = 59/252 (23%)

Query: 189 KTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNEST 248
           K + ++   +P+IKR   ++R+C+T +     SP  K      E+  +N ++++ +  S+
Sbjct: 722 KKDTTDKSSKPQIKRG--KRRYCNTEECLKTGSPGKK------EEKAKN-KESLCMENSS 772

Query: 249 GPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILP 308
                +S  ++    K++ T   TKK+ G               + K   L+T G     
Sbjct: 773 N----SSSDEDEEETKAKMT--PTKKYNGL--------------EEKRKSLRTTGFY--- 809

Query: 309 GAKIPKITNLKERKTSLSDLNDPIILSSDDDDDND----------RTNRRESISPQPADS 358
                  + + E++  L + +D  + +S   D  D          +   +E  S    ++
Sbjct: 810 ----SGFSEVAEKRIKLLNNSDERLQNSRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEA 865

Query: 359 ACSSP--APSTGKVEAALN----ENTCRAERELRSIPE---DS---ELNTVTL-PRKARM 405
           A S P  AP  G  E +L     E +C    EL   P    DS   E  TV +  RKA  
Sbjct: 866 AASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEF 925

Query: 406 KDQFGNSIINTP 417
                NS++NTP
Sbjct: 926 PSSGSNSVLNTP 937


>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
          Length = 1312

 Score = 33.9 bits (76), Expect = 0.88
 Identities = 59/252 (23%), Positives = 102/252 (40%), Gaps = 59/252 (23%)

Query: 189  KTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNEST 248
            K + ++   +P+IKR   ++R+C+T +     SP  K      E+  +N ++++ +  S+
Sbjct: 808  KKDTTDKSSKPQIKRG--KRRYCNTEECLKTGSPGKK------EEKAKN-KESLCMENSS 858

Query: 249  GPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILP 308
                 +S  ++    K++ T   TKK+ G               + K   L+T G     
Sbjct: 859  N----SSSDEDEEETKAKMT--PTKKYNGL--------------EEKRKSLRTTGFY--- 895

Query: 309  GAKIPKITNLKERKTSLSDLNDPIILSSDDDDDND----------RTNRRESISPQPADS 358
                   + + E++  L + +D  + +S   D  D          +   +E  S    ++
Sbjct: 896  ----SGFSEVAEKRIKLLNNSDERLQNSRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEA 951

Query: 359  ACSSP--APSTGKVEAALN----ENTCRAERELRSIPE---DS---ELNTVTL-PRKARM 405
            A S P  AP  G  E +L     E +C    EL   P    DS   E  TV +  RKA  
Sbjct: 952  AASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEF 1011

Query: 406  KDQFGNSIINTP 417
                 NS++NTP
Sbjct: 1012 PSSGSNSVLNTP 1023


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 28/142 (19%)

Query: 837 IDSNPGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQN 896
           ++ +  +E S+     N+       K++    SEN EF   +  S+KV D   SE     
Sbjct: 570 LEKDLDEEGSEKELHENVLD-----KELEENDSENSEFE--DDGSEKVLDEEGSEREFDE 622

Query: 897 ESLSSTHHTDGLSKIRLNYSDESPE-----------AGKMLEDELVD---FSEDQDNQDD 942
           +S       D   K+  + SDE  +           A K  E+   D   F E  D +D+
Sbjct: 623 DSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDE 682

Query: 943 SSD-------DGFLADDNCSSE 957
            +D       D  L +D+ S+E
Sbjct: 683 DADGKEVEDADEKLFEDDDSNE 704


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 28/142 (19%)

Query: 837 IDSNPGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQN 896
           ++ +  +E S+     N+       K++    SEN EF   +  S+KV D   SE     
Sbjct: 570 LEKDLDEEGSEKELHENVLD-----KELEENDSENSEFE--DDGSEKVLDEEGSEREFDE 622

Query: 897 ESLSSTHHTDGLSKIRLNYSDESPE-----------AGKMLEDELVD---FSEDQDNQDD 942
           +S       D   K+  + SDE  +           A K  E+   D   F E  D +D+
Sbjct: 623 DSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDE 682

Query: 943 SSD-------DGFLADDNCSSE 957
            +D       D  L +D+ S+E
Sbjct: 683 DADGKEVEDADEKLFEDDDSNE 704


>gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo
           sapiens]
          Length = 554

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 47/200 (23%), Positives = 75/200 (37%), Gaps = 36/200 (18%)

Query: 38  HEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSES 97
           H E    D+D DG  L + DEDED +               + SGE  L + +RR  + +
Sbjct: 355 HREYQANDSDSDGPILYTDDEDEDED--------------EDGSGESALASKIRRRDTLA 400

Query: 98  FKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDR 157
            K   GN      L  +K + + T            G +     +Q P  +   Q ++  
Sbjct: 401 IKL--GNRPSKKEL-EDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNI-L 456

Query: 158 KERKEYPPHVQKVEINPVRLSRLQGV---------ERIMKKTEESESQVEPEIKRKVQQK 208
           K++ E      K+E+   RLSR   +          RI++  E  E    P+  R+    
Sbjct: 457 KQKNEEEEQEAKMELKR-RLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRAD-- 513

Query: 209 RHCSTYQPTPPLSPASKKCL 228
                 +P   L+PA K  +
Sbjct: 514 ------KPWARLTPADKAAI 527


>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
           sapiens]
          Length = 634

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 47/200 (23%), Positives = 75/200 (37%), Gaps = 36/200 (18%)

Query: 38  HEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSES 97
           H E    D+D DG  L + DEDED +               + SGE  L + +RR  + +
Sbjct: 435 HREYQANDSDSDGPILYTDDEDEDED--------------EDGSGESALASKIRRRDTLA 480

Query: 98  FKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDR 157
            K   GN      L  +K + + T            G +     +Q P  +   Q ++  
Sbjct: 481 IKL--GNRPSKKEL-EDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNI-L 536

Query: 158 KERKEYPPHVQKVEINPVRLSRLQGV---------ERIMKKTEESESQVEPEIKRKVQQK 208
           K++ E      K+E+   RLSR   +          RI++  E  E    P+  R+    
Sbjct: 537 KQKNEEEEQEAKMELKR-RLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRAD-- 593

Query: 209 RHCSTYQPTPPLSPASKKCL 228
                 +P   L+PA K  +
Sbjct: 594 ------KPWARLTPADKAAI 607


>gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 47/200 (23%), Positives = 75/200 (37%), Gaps = 36/200 (18%)

Query: 38  HEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSES 97
           H E    D+D DG  L + DEDED +               + SGE  L + +RR  + +
Sbjct: 366 HREYQANDSDSDGPILYTDDEDEDED--------------EDGSGESALASKIRRRDTLA 411

Query: 98  FKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDR 157
            K   GN      L  +K + + T            G +     +Q P  +   Q ++  
Sbjct: 412 IKL--GNRPSKKEL-EDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNI-L 467

Query: 158 KERKEYPPHVQKVEINPVRLSRLQGV---------ERIMKKTEESESQVEPEIKRKVQQK 208
           K++ E      K+E+   RLSR   +          RI++  E  E    P+  R+    
Sbjct: 468 KQKNEEEEQEAKMELKR-RLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRAD-- 524

Query: 209 RHCSTYQPTPPLSPASKKCL 228
                 +P   L+PA K  +
Sbjct: 525 ------KPWARLTPADKAAI 538


>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
           sapiens]
          Length = 645

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 47/200 (23%), Positives = 75/200 (37%), Gaps = 36/200 (18%)

Query: 38  HEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSES 97
           H E    D+D DG  L + DEDED +               + SGE  L + +RR  + +
Sbjct: 446 HREYQANDSDSDGPILYTDDEDEDED--------------EDGSGESALASKIRRRDTLA 491

Query: 98  FKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDR 157
            K   GN      L  +K + + T            G +     +Q P  +   Q ++  
Sbjct: 492 IKL--GNRPSKKEL-EDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNI-L 547

Query: 158 KERKEYPPHVQKVEINPVRLSRLQGV---------ERIMKKTEESESQVEPEIKRKVQQK 208
           K++ E      K+E+   RLSR   +          RI++  E  E    P+  R+    
Sbjct: 548 KQKNEEEEQEAKMELKR-RLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRAD-- 604

Query: 209 RHCSTYQPTPPLSPASKKCL 228
                 +P   L+PA K  +
Sbjct: 605 ------KPWARLTPADKAAI 618


>gi|33942066 SUMO/sentrin specific peptidase family member 8 [Homo
            sapiens]
          Length = 212

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 12/98 (12%)

Query: 983  SRSNVV--KILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVES 1040
            SRSN V  K + E LE  +  +KG K +F ++       K P Q N  DCG+YV+   E+
Sbjct: 122  SRSNSVHAKQVAEKLEA-FLGRKGDKLAFVEE-------KAPAQQNSYDCGMYVICNTEA 173

Query: 1041 FFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKL 1078
              +N     +   +L     P  +  KR E +++I  L
Sbjct: 174  LCQN--FFRQQTESLLQLLTPAYITKKRGEWKDLIATL 209


>gi|9910430 matrix, extracellular phosphoglycoprotein with ASARM
           motif (bone) [Homo sapiens]
          Length = 525

 Score = 33.1 bits (74), Expect = 1.5
 Identities = 34/140 (24%), Positives = 54/140 (38%), Gaps = 22/140 (15%)

Query: 11  GEITFLEALARSESKRDGGFKN----NWSFDH------EEESEGDTDK-DGTNLLSVDED 59
           G   F E   R  ++ D G +N       F +      E+  EG +D  + TN   + ++
Sbjct: 343 GSTNFKELPGREGNRVDAGSQNAHQGKVEFHYPPAPSKEKRKEGSSDAAESTNYNEIPKN 402

Query: 60  EDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSE 119
               T KG   + R++   N    F  K      KS+      G PI    L N  K   
Sbjct: 403 GKGSTRKGVDHSNRNQATLNEKQRFPSK-----GKSQ------GLPIPSRGLDNEIKNEM 451

Query: 120 NTQNTSLCSGTVVHGRRFHH 139
           ++ N       + HGR++H+
Sbjct: 452 DSFNGPSHENIITHGRKYHY 471


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,176,632
Number of Sequences: 37866
Number of extensions: 2160216
Number of successful extensions: 7408
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 7099
Number of HSP's gapped (non-prelim): 374
length of query: 1112
length of database: 18,247,518
effective HSP length: 113
effective length of query: 999
effective length of database: 13,968,660
effective search space: 13954691340
effective search space used: 13954691340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.