BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|156071452 nardilysin isoform b [Homo sapiens] (1151 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|156071452 nardilysin isoform b [Homo sapiens] 2341 0.0 gi|156071450 nardilysin isoform a [Homo sapiens] 2258 0.0 gi|155969707 insulin-degrading enzyme [Homo sapiens] 541 e-153 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 64 8e-10 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 59 2e-08 gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 57 8e-08 gi|55956788 nucleolin [Homo sapiens] 57 1e-07 gi|17975763 myelin transcription factor 1 [Homo sapiens] 57 1e-07 gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 57 1e-07 gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 57 1e-07 gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 57 1e-07 gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 56 2e-07 gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 56 2e-07 gi|170763500 SET translocation (myeloid leukemia-associated) iso... 56 2e-07 gi|170763498 SET translocation (myeloid leukemia-associated) iso... 56 2e-07 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 55 3e-07 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 55 3e-07 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 55 3e-07 gi|115529449 upstream binding transcription factor, RNA polymera... 55 4e-07 gi|115529451 upstream binding transcription factor, RNA polymera... 55 4e-07 gi|7657671 upstream binding transcription factor, RNA polymerase... 55 4e-07 gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 54 7e-07 gi|210032580 SET domain containing 1B [Homo sapiens] 53 1e-06 gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 53 2e-06 gi|42740903 MTERF domain containing 2 [Homo sapiens] 52 2e-06 gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens] 52 2e-06 gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens] 52 2e-06 gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens] 52 2e-06 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 52 3e-06 gi|18093112 ABT1-associated protein [Homo sapiens] 52 3e-06 >gi|156071452 nardilysin isoform b [Homo sapiens] Length = 1151 Score = 2341 bits (6067), Expect = 0.0 Identities = 1151/1151 (100%), Positives = 1151/1151 (100%) Query: 1 MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60 MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC Sbjct: 1 MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60 Query: 61 SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120 SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN Sbjct: 61 SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120 Query: 121 GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD 180 GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD Sbjct: 121 GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD 180 Query: 181 EHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVF 240 EHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVF Sbjct: 181 EHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVF 240 Query: 241 MGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMI 300 MGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMI Sbjct: 241 MGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMI 300 Query: 301 RDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNI 360 RDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNI Sbjct: 301 RDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNI 360 Query: 361 DTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPF 420 DTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPF Sbjct: 361 DTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPF 420 Query: 421 DTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKK 480 DTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKK Sbjct: 421 DTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKK 480 Query: 481 CWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKR 540 CWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKR Sbjct: 481 CWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKR 540 Query: 541 IFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALN 600 IFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALN Sbjct: 541 IFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALN 600 Query: 601 QLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAEN 660 QLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAEN Sbjct: 601 QLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAEN 660 Query: 661 KYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAA 720 KYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAA Sbjct: 661 KYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAA 720 Query: 721 NVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDY 780 NVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDY Sbjct: 721 NVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDY 780 Query: 781 LAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLS 840 LAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLS Sbjct: 781 LAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLS 840 Query: 841 LESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELP 900 LESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELP Sbjct: 841 LESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELP 900 Query: 901 SGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGY 960 SGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGY Sbjct: 901 SGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGY 960 Query: 961 HVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTA 1020 HVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTA Sbjct: 961 HVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTA 1020 Query: 1021 LIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGS 1080 LIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGS Sbjct: 1021 LIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGS 1080 Query: 1081 KMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTT 1140 KMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTT Sbjct: 1081 KMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTT 1140 Query: 1141 LNLLPYHKIVK 1151 LNLLPYHKIVK Sbjct: 1141 LNLLPYHKIVK 1151 >gi|156071450 nardilysin isoform a [Homo sapiens] Length = 1219 Score = 2258 bits (5850), Expect = 0.0 Identities = 1131/1219 (92%), Positives = 1139/1219 (93%), Gaps = 68/1219 (5%) Query: 1 MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60 MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC Sbjct: 1 MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60 Query: 61 SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120 SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN Sbjct: 61 SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120 Query: 121 GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFD- 179 GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFD Sbjct: 121 GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD 180 Query: 180 ------DEHDDDLD------------TEDNELEEL------------------------- 196 D D++L+ TE +L+ L Sbjct: 181 EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLL 240 Query: 197 ------------EERA------------EARKKTTEKQSAAALCVGVGSFADPDDLPGLA 232 E R+ E + +T SAAALCVGVGSFADPDDLPGLA Sbjct: 241 VETRNLYGVVGAESRSAPVQHLAGWQAEEQQGETDTVLSAAALCVGVGSFADPDDLPGLA 300 Query: 233 HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ 292 HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ Sbjct: 301 HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ 360 Query: 293 FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK 352 FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK Sbjct: 361 FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK 420 Query: 353 HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN 412 HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN Sbjct: 421 HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN 480 Query: 413 FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS 472 FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS Sbjct: 481 FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS 540 Query: 473 ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML 532 ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML Sbjct: 541 ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML 600 Query: 533 QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP 592 QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP Sbjct: 601 QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP 660 Query: 593 EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP 652 EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP Sbjct: 661 EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP 720 Query: 653 DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS 712 DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS Sbjct: 721 DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS 780 Query: 713 PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL 772 PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL Sbjct: 781 PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL 840 Query: 773 LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY 832 LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY Sbjct: 841 LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY 900 Query: 833 QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV 892 QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV Sbjct: 901 QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV 960 Query: 893 QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL 952 QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL Sbjct: 961 QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL 1020 Query: 953 RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE 1012 RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE Sbjct: 1021 RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE 1080 Query: 1013 AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF 1072 AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF Sbjct: 1081 AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF 1140 Query: 1073 KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT 1132 KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT Sbjct: 1141 KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT 1200 Query: 1133 DIRAFTTTLNLLPYHKIVK 1151 DIRAFTTTLNLLPYHKIVK Sbjct: 1201 DIRAFTTTLNLLPYHKIVK 1219 >gi|155969707 insulin-degrading enzyme [Homo sapiens] Length = 1019 Score = 541 bits (1395), Expect = e-153 Identities = 308/891 (34%), Positives = 495/891 (55%), Gaps = 21/891 (2%) Query: 206 TTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNA 265 TT+K S+AAL V +GS +DP ++ GL+HF EHM+F+G+ KYP EN + FL +H GS NA Sbjct: 82 TTDK-SSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNA 140 Query: 266 STDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANR 325 T E T + FDV ++ + ALDR+AQFF+ PL DREV AVDSE++ +DA R Sbjct: 141 FTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWR 200 Query: 326 KEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQS 385 L + P HP KF GN TL+ P + ID L +F YYSS+ M + V Sbjct: 201 LFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLG 260 Query: 386 KETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWA 445 +E+LD L V ++FS++ N +P P F PF +LY++VPI+ I L +T+ Sbjct: 261 RESLDDLTNLVVKLFSEVENKNVPLPEFPE--HPFQEEHLKQLYKIVPIKDIRNLYVTFP 318 Query: 446 LPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFS 505 +P Q++Y+ P HY+ L+GHEG GS+LS L+ K W L GG E + F Sbjct: 319 IPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGA----RGFMFFI 374 Query: 506 ISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYV 565 I++ LT+EG H ++ +FQY++ L+ GP++ +F+E + + F ++++ P Y Sbjct: 375 INVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYT 434 Query: 566 ENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEK 625 + + YPL+++LT + LL E++P++I L++L P+ + ++S + EGK D E+ Sbjct: 435 SKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEE 494 Query: 626 WFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVN 685 W+GTQY E I + + W N +LN LP +N++I T+F + + T YP I + Sbjct: 495 WYGTQYKQEAIPDEVIKKW-QNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKD 553 Query: 686 TPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADV 745 T LW+K+D+KF +PKA + F SP + + +++ +L +L E AY A++ Sbjct: 554 TAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAEL 613 Query: 746 AQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNI 805 A L Y L +G+ + VKG+N K P+L + II+ +A F F +I E ++ N Sbjct: 614 AGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNF 673 Query: 806 LI-KPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGN 864 +P A L++ W+ D+ + +D ++L L +F+ + S+L +E L+ GN Sbjct: 674 RAEQPHQHAMYYLRLLMTEVAWTK-DELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGN 732 Query: 865 VTSTESMDFLKYVVDKL----NFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEV 920 +T ++ ++ V D L + KPL V+++ V+LP + N+ N + Sbjct: 733 ITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFV-YQQRNEVHNNCGI 791 Query: 921 TVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVG 980 +YYQ+ +S E +EL + EPCF+ LRTK+ LGY V+ R +GI G + Sbjct: 792 EIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQ 851 Query: 981 TQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNW 1040 ++ + ++ ++E FL + E+ IE++TEEAF + AL + + L E + W Sbjct: 852 SEKPPH---YLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYW 908 Query: 1041 NEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFK---AHRGPGSKMLSVHVV 1088 E+++QQY FDR E+ LK+ +K D++ ++K A P +SVHV+ Sbjct: 909 GEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVL 959 Score = 35.8 bits (81), Expect = 0.24 Identities = 15/27 (55%), Positives = 21/27 (77%) Query: 103 IVKSPSDPKQYRYIKLQNGLQALLISD 129 I KSP D ++YR ++L NG++ LLISD Sbjct: 54 ITKSPEDKREYRGLELANGIKVLLISD 80 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 63.9 bits (154), Expect = 8e-10 Identities = 27/64 (42%), Positives = 48/64 (75%) Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201 ++EEEEE EEEEE+++E+ E E+D+EE F++E+E ++E +++ + E+ ELEE EE + Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950 Query: 202 ARKK 205 ++ Sbjct: 951 EEEE 954 Score = 52.0 bits (123), Expect = 3e-06 Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 6/77 (7%) Query: 128 SDLSNMEGKTGNTTDDEEEEEVEE-EEEDDDEDSGAEIEDDDEEGF-----DDEDEFDDE 181 SD E + ++EEEEE E+ EEE++DE+ E E+++EE F ++E E ++E Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945 Query: 182 HDDDLDTEDNELEELEE 198 +++ + E+ ELEE+E+ Sbjct: 946 EEEEDEEEEEELEEVED 962 Score = 49.3 bits (116), Expect = 2e-05 Identities = 21/61 (34%), Positives = 41/61 (67%) Query: 150 EEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEK 209 EEEEE+++E+ E E+++EE F++E+E ++E+ ++ + E+ E EE E E + E+ Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947 Query: 210 Q 210 + Sbjct: 948 E 948 Score = 45.4 bits (106), Expect = 3e-04 Identities = 21/53 (39%), Positives = 35/53 (66%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 +EEEEE EE EE+ +E+ G E+++EE ++E+E ++ D + T E+EE Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974 Score = 38.1 bits (87), Expect = 0.049 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 20/71 (28%) Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 N++D+EEEEE EEEEE+++E+ +E +D + E++E E EE Sbjct: 884 NSSDEEEEEEEEEEEEEEEEE--------------------EEEEDFEEEEEDEEEYFEE 923 Query: 199 RAEARKKTTEK 209 E ++ E+ Sbjct: 924 EEEEEEEFEEE 934 Score = 30.8 bits (68), Expect = 7.7 Identities = 14/47 (29%), Positives = 28/47 (59%) Query: 164 IEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQ 210 I DEE ++E+E ++E +++ + ED E EE +E ++ E++ Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 59.3 bits (142), Expect = 2e-08 Identities = 31/79 (39%), Positives = 51/79 (64%), Gaps = 3/79 (3%) Query: 134 EGKTGNTTDDEEEEEVEEEE--EDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191 E + G +DE++E+ EEEE E+DDED E ++DD+E ++E+EF + +D+ + ED Sbjct: 170 EDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDE 229 Query: 192 ELEELEERAEARKKTTEKQ 210 E EE + E RK+ T+ + Sbjct: 230 E-EEEGGKGEKRKRETDDE 247 Score = 56.2 bits (134), Expect = 2e-07 Identities = 31/84 (36%), Positives = 48/84 (57%), Gaps = 7/84 (8%) Query: 134 EGKTGNTTDDEEEEEVEEEEEDDDEDSGAE------IEDDDEEGFDDEDEFDDEHDD-DL 186 + + ++EE+EE E+EE++DDED E ED+D EG +D+DE +E ++ L Sbjct: 159 DAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGL 218 Query: 187 DTEDNELEELEERAEARKKTTEKQ 210 D ED + +E EE E K K+ Sbjct: 219 DEEDEDEDEDEEEEEGGKGEKRKR 242 Score = 47.0 bits (110), Expect = 1e-04 Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 9/81 (11%) Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181 L L D + E + +D E + EEEE+++ ED E ++DDE+G +E+EFD+E Sbjct: 139 LPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGED---EEDEDDEDG--EEEEFDEE 193 Query: 182 HDDDLDTE----DNELEELEE 198 D+D D E D+E+ E EE Sbjct: 194 DDEDEDVEGDEDDDEVSEEEE 214 Score = 39.7 bits (91), Expect = 0.017 Identities = 21/49 (42%), Positives = 32/49 (65%), Gaps = 6/49 (12%) Query: 143 DEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED---EFDDEHDDD 185 DE+++EV EEEE+ D+ED + ++++EEG E E DDE +DD Sbjct: 203 DEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251 Score = 32.3 bits (72), Expect = 2.7 Identities = 29/112 (25%), Positives = 43/112 (38%), Gaps = 20/112 (17%) Query: 64 DLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDP-EIVKSPSDPKQYRYIKLQNGL 122 D + +G D E DE +E+G D E V+ D Sbjct: 159 DAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD------------ 206 Query: 123 QALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDD 174 ++S E + G +DE+E+E EEEEE + + D+EG DD Sbjct: 207 -----DEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEK--RKRETDDEGEDD 251 >gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] Length = 1759 Score = 57.4 bits (137), Expect = 8e-08 Identities = 35/80 (43%), Positives = 43/80 (53%), Gaps = 8/80 (10%) Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201 D+EEE E+ EEE +DDED EDDDE DD+DE DDE DDD D + E L E A Sbjct: 1677 DEEEELELPEEEAEDDED-----EDDDE---DDDDEDDDEDDDDEDLRTDSEESLPEAAA 1728 Query: 202 ARKKTTEKQSAAALCVGVGS 221 + A A +G+ Sbjct: 1729 EAAGAGARTPALAALAALGA 1748 Score = 36.6 bits (83), Expect = 0.14 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 12/70 (17%) Query: 160 SGAEIEDDDEEGF--------DDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQS 211 +G ++D+EE DDEDE DDE DDD D ++++ +E + R ++ + E Sbjct: 1670 AGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDE-DLRTDSEESLPE--- 1725 Query: 212 AAALCVGVGS 221 AAA G G+ Sbjct: 1726 AAAEAAGAGA 1735 Score = 32.0 bits (71), Expect = 3.5 Identities = 13/46 (28%), Positives = 27/46 (58%), Gaps = 3/46 (6%) Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDD 174 +L E + DD+E+++ E+++EDDD++ ++ D EE + Sbjct: 1683 ELPEEEAEDDEDEDDDEDDDDEDDDEDDDDE---DLRTDSEESLPE 1725 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 57.0 bits (136), Expect = 1e-07 Identities = 40/109 (36%), Positives = 52/109 (47%), Gaps = 19/109 (17%) Query: 135 GKTGNTTD-DEEEEEVEEEEEDDDEDSGAEIEDDDE---------------EGFDDEDEF 178 GK D DEEE++ EE+E+DDED E ED+DE E DDED+ Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDED---EDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193 Query: 179 DDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDD 227 DDE DDD + +D+E E +E KK + A V + DD Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDD 242 Score = 55.5 bits (132), Expect = 3e-07 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 34/187 (18%) Query: 47 ILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKS 106 ++A PG+ A + G G+N++ ++S+EE S + D E Sbjct: 118 LVATPGKKGAA-------IPAKGAKNGKNAK-----KEDSDEEEDDDSEEDEEDDE--DE 163 Query: 107 PSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDD--------- 157 D + ++ A D + + + DD+EE++ EEE + Sbjct: 164 DEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAK 223 Query: 158 ----------EDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE-LEERAEARKKT 206 ED E +D+DE+ DDED+ DD+ +DD + E+ E EE ++E RKK Sbjct: 224 VVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283 Query: 207 TEKQSAA 213 KQ AA Sbjct: 284 MAKQKAA 290 Score = 40.0 bits (92), Expect = 0.013 Identities = 31/140 (22%), Positives = 63/140 (45%), Gaps = 4/140 (2%) Query: 79 ARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTG 138 A A SE+E + D + + S+ + + A ++ + + Sbjct: 177 AAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDE 236 Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 + +D+E+E+ +++E+D+D+D EDD+EE ++E+E E E + + E Sbjct: 237 DEEEDDEDEDDDDDEDDEDDDD----EDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292 Query: 199 RAEARKKTTEKQSAAALCVG 218 + + + TE +A L VG Sbjct: 293 AKKQKVEGTEPTTAFNLFVG 312 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 57.0 bits (136), Expect = 1e-07 Identities = 33/123 (26%), Positives = 64/123 (52%), Gaps = 8/123 (6%) Query: 70 QDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNG-------L 122 +DLG+ ++ G +E G+ S G+ + P D ++ + + L Sbjct: 182 EDLGQAAKPGP-GIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240 Query: 123 QALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEH 182 + + S +G + +DEEEEE EEEEE+D+E+ E E+++EE ++E+E ++E Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300 Query: 183 DDD 185 +++ Sbjct: 301 EEE 303 >gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 1 [Homo sapiens] Length = 268 Score = 56.6 bits (135), Expect = 1e-07 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 8/85 (9%) Query: 132 NMEGKTGNTTDDEEEEEVEEEEEDDDED-SGAEIEDDDEE---GFDDEDEFDDEHDDDLD 187 N G ++EEEEE E+E+ED+DED +G+E+ + +EE + ++E DE DDD Sbjct: 176 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 235 Query: 188 TEDNELEELEE----RAEARKKTTE 208 E+ E EE EE R E RK+ E Sbjct: 236 VEEGEEEEEEEEGGLRGEKRKRDAE 260 Score = 48.9 bits (115), Expect = 3e-05 Identities = 24/66 (36%), Positives = 42/66 (63%), Gaps = 7/66 (10%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDE------EGFDDEDEFDDEHDDDLDTEDNEL-EE 195 D+E+ E + EE+DDED + E+++E EG+++E+E ++E D+D D +++E E Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208 Query: 196 LEERAE 201 L E E Sbjct: 209 LGEGEE 214 Score = 44.7 bits (104), Expect = 5e-04 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181 LQ + D + E +++E++E+ +E++E+++E+ E +EE ++E+E +DE Sbjct: 139 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE 198 Query: 182 HDDDLDTEDNELEELEE 198 D+D D +EL E EE Sbjct: 199 -DEDEDEAGSELGEGEE 214 Score = 44.3 bits (103), Expect = 7e-04 Identities = 25/77 (32%), Positives = 45/77 (58%), Gaps = 7/77 (9%) Query: 126 LISDLSNMEG--KTGNTTDDEEEEEVEEEEEDDDEDSGAEIE-----DDDEEGFDDEDEF 178 L+ ++ ++G + N D EEE+ E+ +EDD+E+ E +++EE ++EDE Sbjct: 138 LLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 197 Query: 179 DDEHDDDLDTEDNELEE 195 +DE +D+ +E E EE Sbjct: 198 EDEDEDEAGSELGEGEE 214 Score = 35.8 bits (81), Expect = 0.24 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Query: 146 EEEVEEEEEDDD-EDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTED 190 +EE+++EE+DDD + G E E+++E G E D DD + +D Sbjct: 223 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268 Score = 33.1 bits (74), Expect = 1.6 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 22/94 (23%) Query: 84 DESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD 143 DE E+E GS G+ E+ GL L+ ++ + E DD Sbjct: 197 DEDEDEDEAGSELGEGEEEV-----------------GLSYLMKEEIQDEEDD-----DD 234 Query: 144 EEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177 EE EEEEE++ G + + D E+ ++ED+ Sbjct: 235 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268 >gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 2 [Homo sapiens] Length = 227 Score = 56.6 bits (135), Expect = 1e-07 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 8/85 (9%) Query: 132 NMEGKTGNTTDDEEEEEVEEEEEDDDED-SGAEIEDDDEE---GFDDEDEFDDEHDDDLD 187 N G ++EEEEE E+E+ED+DED +G+E+ + +EE + ++E DE DDD Sbjct: 135 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 194 Query: 188 TEDNELEELEE----RAEARKKTTE 208 E+ E EE EE R E RK+ E Sbjct: 195 VEEGEEEEEEEEGGLRGEKRKRDAE 219 Score = 48.9 bits (115), Expect = 3e-05 Identities = 24/66 (36%), Positives = 42/66 (63%), Gaps = 7/66 (10%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDE------EGFDDEDEFDDEHDDDLDTEDNEL-EE 195 D+E+ E + EE+DDED + E+++E EG+++E+E ++E D+D D +++E E Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167 Query: 196 LEERAE 201 L E E Sbjct: 168 LGEGEE 173 Score = 44.7 bits (104), Expect = 5e-04 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181 LQ + D + E +++E++E+ +E++E+++E+ E +EE ++E+E +DE Sbjct: 98 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE 157 Query: 182 HDDDLDTEDNELEELEE 198 D+D D +EL E EE Sbjct: 158 -DEDEDEAGSELGEGEE 173 Score = 44.3 bits (103), Expect = 7e-04 Identities = 25/77 (32%), Positives = 45/77 (58%), Gaps = 7/77 (9%) Query: 126 LISDLSNMEG--KTGNTTDDEEEEEVEEEEEDDDEDSGAEIE-----DDDEEGFDDEDEF 178 L+ ++ ++G + N D EEE+ E+ +EDD+E+ E +++EE ++EDE Sbjct: 97 LLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 156 Query: 179 DDEHDDDLDTEDNELEE 195 +DE +D+ +E E EE Sbjct: 157 EDEDEDEAGSELGEGEE 173 Score = 35.8 bits (81), Expect = 0.24 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Query: 146 EEEVEEEEEDDD-EDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTED 190 +EE+++EE+DDD + G E E+++E G E D DD + +D Sbjct: 182 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227 Score = 33.1 bits (74), Expect = 1.6 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 22/94 (23%) Query: 84 DESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD 143 DE E+E GS G+ E+ GL L+ ++ + E DD Sbjct: 156 DEDEDEDEAGSELGEGEEEV-----------------GLSYLMKEEIQDEEDD-----DD 193 Query: 144 EEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177 EE EEEEE++ G + + D E+ ++ED+ Sbjct: 194 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227 >gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 3 [Homo sapiens] Length = 220 Score = 56.6 bits (135), Expect = 1e-07 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 8/85 (9%) Query: 132 NMEGKTGNTTDDEEEEEVEEEEEDDDED-SGAEIEDDDEE---GFDDEDEFDDEHDDDLD 187 N G ++EEEEE E+E+ED+DED +G+E+ + +EE + ++E DE DDD Sbjct: 128 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 187 Query: 188 TEDNELEELEE----RAEARKKTTE 208 E+ E EE EE R E RK+ E Sbjct: 188 VEEGEEEEEEEEGGLRGEKRKRDAE 212 Score = 48.9 bits (115), Expect = 3e-05 Identities = 24/66 (36%), Positives = 42/66 (63%), Gaps = 7/66 (10%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDE------EGFDDEDEFDDEHDDDLDTEDNEL-EE 195 D+E+ E + EE+DDED + E+++E EG+++E+E ++E D+D D +++E E Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 160 Query: 196 LEERAE 201 L E E Sbjct: 161 LGEGEE 166 Score = 44.7 bits (104), Expect = 5e-04 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181 LQ + D + E +++E++E+ +E++E+++E+ E +EE ++E+E +DE Sbjct: 91 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE 150 Query: 182 HDDDLDTEDNELEELEE 198 D+D D +EL E EE Sbjct: 151 -DEDEDEAGSELGEGEE 166 Score = 44.3 bits (103), Expect = 7e-04 Identities = 25/77 (32%), Positives = 45/77 (58%), Gaps = 7/77 (9%) Query: 126 LISDLSNMEG--KTGNTTDDEEEEEVEEEEEDDDEDSGAEIE-----DDDEEGFDDEDEF 178 L+ ++ ++G + N D EEE+ E+ +EDD+E+ E +++EE ++EDE Sbjct: 90 LLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 149 Query: 179 DDEHDDDLDTEDNELEE 195 +DE +D+ +E E EE Sbjct: 150 EDEDEDEAGSELGEGEE 166 Score = 35.8 bits (81), Expect = 0.24 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Query: 146 EEEVEEEEEDDD-EDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTED 190 +EE+++EE+DDD + G E E+++E G E D DD + +D Sbjct: 175 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220 Score = 33.1 bits (74), Expect = 1.6 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 22/94 (23%) Query: 84 DESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD 143 DE E+E GS G+ E+ GL L+ ++ + E DD Sbjct: 149 DEDEDEDEAGSELGEGEEEV-----------------GLSYLMKEEIQDEEDD-----DD 186 Query: 144 EEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177 EE EEEEE++ G + + D E+ ++ED+ Sbjct: 187 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220 >gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 56.2 bits (134), Expect = 2e-07 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Query: 134 EGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIE--DDDEEGFDDEDEFD-DEHDDDLDTED 190 E + G D E E+ EEEE D++ED ++E DD +E ++E+EF D+ +DD D ++ Sbjct: 190 EDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDE 249 Query: 191 NELEELEERAEARKKTTEKQ 210 +E EE + E RK+ T+ + Sbjct: 250 DEEEEESGKGENRKRETDDE 269 Score = 38.9 bits (89), Expect = 0.028 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEA 202 D + E +E + D + G + E++DEEG EDE D E++D E+ EL+E E+ E Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEG---EDEKDXENEDG---EEEELDEEEDEDED 219 Query: 203 RKKTTEKQSAAALCVGVGSFADPDD 227 + +K + G D DD Sbjct: 220 VEGDDDKDEVSEEEEEFGLDKDEDD 244 Score = 38.9 bits (89), Expect = 0.028 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 8/63 (12%) Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEE----DDDEDSGAEIEDDDEE----GFDDEDEFDD 180 +L E + + D++++EV EEEE D DED E ED++EE G + + E DD Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDD 268 Query: 181 EHD 183 E D Sbjct: 269 EED 271 Score = 34.7 bits (78), Expect = 0.54 Identities = 29/110 (26%), Positives = 41/110 (37%), Gaps = 18/110 (16%) Query: 64 DLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQ 123 D Q +G D E D E+G L D + D K Sbjct: 179 DAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKD----------- 227 Query: 124 ALLISDLSNMEGKTG--NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEG 171 ++S E + G DDE+E+E EEEEE ++ DD+E+G Sbjct: 228 -----EVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272 >gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 56.2 bits (134), Expect = 2e-07 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 3/80 (3%) Query: 134 EGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIE--DDDEEGFDDEDEFD-DEHDDDLDTED 190 E + G D E E+ EEEE D++ED ++E DD +E ++E+EF D+ +DD D ++ Sbjct: 190 EDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDE 249 Query: 191 NELEELEERAEARKKTTEKQ 210 +E EE + E RK+ T+ + Sbjct: 250 DEEEEESGKGENRKRETDDE 269 Score = 38.9 bits (89), Expect = 0.028 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEA 202 D + E +E + D + G + E++DEEG EDE D E++D E+ EL+E E+ E Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEG---EDEKDXENEDG---EEEELDEEEDEDED 219 Query: 203 RKKTTEKQSAAALCVGVGSFADPDD 227 + +K + G D DD Sbjct: 220 VEGDDDKDEVSEEEEEFGLDKDEDD 244 Score = 38.9 bits (89), Expect = 0.028 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 8/63 (12%) Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEE----DDDEDSGAEIEDDDEE----GFDDEDEFDD 180 +L E + + D++++EV EEEE D DED E ED++EE G + + E DD Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDD 268 Query: 181 EHD 183 E D Sbjct: 269 EED 271 Score = 34.7 bits (78), Expect = 0.54 Identities = 29/110 (26%), Positives = 41/110 (37%), Gaps = 18/110 (16%) Query: 64 DLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQ 123 D Q +G D E D E+G L D + D K Sbjct: 179 DAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKD----------- 227 Query: 124 ALLISDLSNMEGKTG--NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEG 171 ++S E + G DDE+E+E EEEEE ++ DD+E+G Sbjct: 228 -----EVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272 >gi|170763500 SET translocation (myeloid leukemia-associated) isoform 1 [Homo sapiens] Length = 290 Score = 55.8 bits (133), Expect = 2e-07 Identities = 29/63 (46%), Positives = 41/63 (65%), Gaps = 1/63 (1%) Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEE-VEEEEEDDDEDSGAEIEDDDEEGFDDEDEF 178 N LQ L+ D+ + EG+ DD+EEEE +E+ +E+ DED G E EDDDE +EDE Sbjct: 228 NPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEG 287 Query: 179 DDE 181 +D+ Sbjct: 288 EDD 290 Score = 50.4 bits (119), Expect = 9e-06 Identities = 23/53 (43%), Positives = 37/53 (69%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 D ++EE E EE+DDD++ +ED DEEG +DE E D++ D+ + E++E E+ Sbjct: 237 DMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGED 289 Score = 41.2 bits (95), Expect = 0.006 Identities = 20/51 (39%), Positives = 35/51 (68%), Gaps = 3/51 (5%) Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 ++++EE + +ED + +D++EEG +D DE DE + + D +D+E EE EE Sbjct: 237 DMDDEEGEGEED---DDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEE 284 >gi|170763498 SET translocation (myeloid leukemia-associated) isoform 2 [Homo sapiens] Length = 277 Score = 55.8 bits (133), Expect = 2e-07 Identities = 29/63 (46%), Positives = 41/63 (65%), Gaps = 1/63 (1%) Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEE-VEEEEEDDDEDSGAEIEDDDEEGFDDEDEF 178 N LQ L+ D+ + EG+ DD+EEEE +E+ +E+ DED G E EDDDE +EDE Sbjct: 215 NPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEG 274 Query: 179 DDE 181 +D+ Sbjct: 275 EDD 277 Score = 50.4 bits (119), Expect = 9e-06 Identities = 23/53 (43%), Positives = 37/53 (69%) Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 D ++EE E EE+DDD++ +ED DEEG +DE E D++ D+ + E++E E+ Sbjct: 224 DMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGED 276 Score = 41.2 bits (95), Expect = 0.006 Identities = 20/51 (39%), Positives = 35/51 (68%), Gaps = 3/51 (5%) Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 ++++EE + +ED + +D++EEG +D DE DE + + D +D+E EE EE Sbjct: 224 DMDDEEGEGEED---DDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEE 271 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 55.5 bits (132), Expect = 3e-07 Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Query: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE-HDDDL 186 S + + G DE+EE+ EE +D+++ G E E+D+E ++E+E ++E DDD Sbjct: 85 SSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE 144 Query: 187 DTEDNELEELEERAEARKKTTEK 209 D ED E EE EE E ++ E+ Sbjct: 145 DGEDVEDEEEEEEEEEEEEEEEE 167 Score = 55.5 bits (132), Expect = 3e-07 Identities = 24/44 (54%), Positives = 37/44 (84%), Gaps = 1/44 (2%) Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDD 185 D EEEEE+EEE+EDDDED G ++ED++EE ++E+E ++E ++D Sbjct: 128 DREEEEEIEEEDEDDDED-GEDVEDEEEEEEEEEEEEEEEENED 170 Score = 53.1 bits (126), Expect = 1e-06 Identities = 25/71 (35%), Positives = 44/71 (61%) Query: 140 TTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEER 199 T D +E+EE E EE +D D + +++DEEG +E+E +E D+D D + ++E+ EE Sbjct: 96 TEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEE 155 Query: 200 AEARKKTTEKQ 210 E ++ E++ Sbjct: 156 EEEEEEEEEEE 166 Score = 50.1 bits (118), Expect = 1e-05 Identities = 25/67 (37%), Positives = 43/67 (64%), Gaps = 5/67 (7%) Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDT 188 + S + G+ +++EE + EEEEE ++ED EDDDE+G D EDE ++E +++ + Sbjct: 109 EYSEDNDEPGDEDEEDEEGDREEEEEIEEED-----EDDDEDGEDVEDEEEEEEEEEEEE 163 Query: 189 EDNELEE 195 E+ E E+ Sbjct: 164 EEEENED 170 Score = 45.8 bits (107), Expect = 2e-04 Identities = 21/58 (36%), Positives = 37/58 (63%) Query: 144 EEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201 E+ +E +E+E+D+E E E+ +EE DD+++ +D D++ + E+ E EE EE E Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169 Score = 44.7 bits (104), Expect = 5e-04 Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 9/82 (10%) Query: 134 EGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHD---------D 184 E + G+ ++EE EE +E++++D ED E E+++EE ++E+E +++H Sbjct: 123 EDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQ 182 Query: 185 DLDTEDNELEELEERAEARKKT 206 D + +DN +E + E K+ Sbjct: 183 DTEKDDNNNDEYDNYDELVAKS 204 Score = 35.8 bits (81), Expect = 0.24 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 145 EEEEVEEEEEDDDEDSGAEIEDDDEEGF-DDEDEFDDEHDDDLDTEDNELEELEERAE 201 + V+E ++ D + E E+D+ E + +D DE DE ++D + + E EE+EE E Sbjct: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE 140 Score = 35.8 bits (81), Expect = 0.24 Identities = 31/131 (23%), Positives = 60/131 (45%), Gaps = 6/131 (4%) Query: 84 DESEEEGRRGSLSN--AGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTT 141 ++ E+EG S N GD + D ++ I+ ++ D ++E + Sbjct: 101 EKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD---EDGEDVEDEEEEEE 157 Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201 ++EEEEE EE E+ I D E+ ++ DE+D+ +D+ + L ++ E A Sbjct: 158 EEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDN-YDELVAKSLLNLGKIAEDAA 216 Query: 202 ARKKTTEKQSA 212 R +T + ++ Sbjct: 217 YRARTESEMNS 227 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 55.5 bits (132), Expect = 3e-07 Identities = 42/143 (29%), Positives = 68/143 (47%), Gaps = 8/143 (5%) Query: 88 EEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD-EEE 146 E RR S S+ E V S + + G +N E + +D EE+ Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDH-----ETGSSGSSDEQGNNTENEEEGVEEDVEED 212 Query: 147 EEVEEEEEDDDE--DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARK 204 EEVEE+ E+D+E + G E E+++EE ++E+E ++E++ D + E + + R+EA Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272 Query: 205 KTTEKQSAAALCVGVGSFADPDD 227 +E S V GS D D Sbjct: 273 SGSESVSFTDGSVRSGSGTDGSD 295 Score = 35.8 bits (81), Expect = 0.24 Identities = 17/74 (22%), Positives = 35/74 (47%) Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201 ++EEEEE EEEEE+++ + + ++ +D E D + + D + Sbjct: 234 EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293 Query: 202 ARKKTTEKQSAAAL 215 + +K E++ A + Sbjct: 294 SDEKKKERKRARGI 307 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 55.5 bits (132), Expect = 3e-07 Identities = 42/143 (29%), Positives = 68/143 (47%), Gaps = 8/143 (5%) Query: 88 EEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD-EEE 146 E RR S S+ E V S + + G +N E + +D EE+ Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDH-----ETGSSGSSDEQGNNTENEEEGVEEDVEED 212 Query: 147 EEVEEEEEDDDE--DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARK 204 EEVEE+ E+D+E + G E E+++EE ++E+E ++E++ D + E + + R+EA Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272 Query: 205 KTTEKQSAAALCVGVGSFADPDD 227 +E S V GS D D Sbjct: 273 SGSESVSFTDGSVRSGSGTDGSD 295 Score = 35.8 bits (81), Expect = 0.24 Identities = 17/74 (22%), Positives = 35/74 (47%) Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201 ++EEEEE EEEEE+++ + + ++ +D E D + + D + Sbjct: 234 EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293 Query: 202 ARKKTTEKQSAAAL 215 + +K E++ A + Sbjct: 294 SDEKKKERKRARGI 307 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 55.1 bits (131), Expect = 4e-07 Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 18/100 (18%) Query: 128 SDLSNMEGKTGNTTDDEEEE--EVEEEEEDDDED--------------SGAEIEDDDEEG 171 S + ++ K+ + DDEE+E E E+EEE+DDE+ S E ED DE Sbjct: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688 Query: 172 FDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQS 211 DDEDE DDE DD + EDNE E + + +++ S Sbjct: 689 EDDEDEDDDEDDD--EDEDNESEGSSSSSSSSGDSSDSDS 726 Score = 50.1 bits (118), Expect = 1e-05 Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 10/128 (7%) Query: 106 SPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIE 165 SP D Y+ + N +++ + L K+ TT + E E++EED+D++ E E Sbjct: 601 SPQDRAAYKEY-ISNKRKSM--TKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEE 657 Query: 166 DDDEEGFDDEDEFD-------DEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVG 218 +DDE G ED D DE +D + E+++ +E ++ + + E + +++ Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS 717 Query: 219 VGSFADPD 226 G +D D Sbjct: 718 SGDSSDSD 725 Score = 36.6 bits (83), Expect = 0.14 Identities = 14/53 (26%), Positives = 29/53 (54%) Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191 ++++DE E+ E EE+D+DED + ++D++ + D D++ N Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 55.1 bits (131), Expect = 4e-07 Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 18/100 (18%) Query: 128 SDLSNMEGKTGNTTDDEEEE--EVEEEEEDDDED--------------SGAEIEDDDEEG 171 S + ++ K+ + DDEE+E E E+EEE+DDE+ S E ED DE Sbjct: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688 Query: 172 FDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQS 211 DDEDE DDE DD + EDNE E + + +++ S Sbjct: 689 EDDEDEDDDEDDD--EDEDNESEGSSSSSSSSGDSSDSDS 726 Score = 50.1 bits (118), Expect = 1e-05 Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 10/128 (7%) Query: 106 SPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIE 165 SP D Y+ + N +++ + L K+ TT + E E++EED+D++ E E Sbjct: 601 SPQDRAAYKEY-ISNKRKSM--TKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEE 657 Query: 166 DDDEEGFDDEDEFD-------DEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVG 218 +DDE G ED D DE +D + E+++ +E ++ + + E + +++ Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS 717 Query: 219 VGSFADPD 226 G +D D Sbjct: 718 SGDSSDSD 725 Score = 36.6 bits (83), Expect = 0.14 Identities = 14/53 (26%), Positives = 29/53 (54%) Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191 ++++DE E+ E EE+D+DED + ++D++ + D D++ N Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 55.1 bits (131), Expect = 4e-07 Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 18/100 (18%) Query: 128 SDLSNMEGKTGNTTDDEEEE--EVEEEEEDDDED--------------SGAEIEDDDEEG 171 S + ++ K+ + DDEE+E E E+EEE+DDE+ S E ED DE Sbjct: 666 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 725 Query: 172 FDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQS 211 DDEDE DDE DD + EDNE E + + +++ S Sbjct: 726 EDDEDEDDDEDDD--EDEDNESEGSSSSSSSSGDSSDSDS 763 Score = 50.1 bits (118), Expect = 1e-05 Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 10/128 (7%) Query: 106 SPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIE 165 SP D Y+ + N +++ + L K+ TT + E E++EED+D++ E E Sbjct: 638 SPQDRAAYKEY-ISNKRKSM--TKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEE 694 Query: 166 DDDEEGFDDEDEFD-------DEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVG 218 +DDE G ED D DE +D + E+++ +E ++ + + E + +++ Sbjct: 695 EDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS 754 Query: 219 VGSFADPD 226 G +D D Sbjct: 755 SGDSSDSD 762 Score = 36.6 bits (83), Expect = 0.14 Identities = 14/53 (26%), Positives = 29/53 (54%) Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191 ++++DE E+ E EE+D+DED + ++D++ + D D++ N Sbjct: 712 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764 >gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] Length = 1390 Score = 54.3 bits (129), Expect = 7e-07 Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 3/72 (4%) Query: 136 KTGNTTDDEEEEEVE--EEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNEL 193 +T T D +E VE EE ED + + E EDD+++ DD+D+ DD+ +DD D ED E Sbjct: 229 RTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGE- 287 Query: 194 EELEERAEARKK 205 EE ++R R++ Sbjct: 288 EENQKRYYLRQR 299 Score = 49.3 bits (116), Expect = 2e-05 Identities = 23/72 (31%), Positives = 43/72 (59%), Gaps = 2/72 (2%) Query: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLD 187 +D + + G+ EE E+ E E++ +DED + +DDD++ DD+D+ DDE ++D + Sbjct: 230 TDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDD--DDDDDEDDEDEEDGE 287 Query: 188 TEDNELEELEER 199 E+ + L +R Sbjct: 288 EENQKRYYLRQR 299 Score = 38.1 bits (87), Expect = 0.049 Identities = 17/64 (26%), Positives = 35/64 (54%) Query: 147 EEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKT 206 + +EE D+ E S E+ +++ +D+ E +D+ DDD D +D++ ++ E+ + Sbjct: 228 QRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGE 287 Query: 207 TEKQ 210 E Q Sbjct: 288 EENQ 291 Score = 34.3 bits (77), Expect = 0.70 Identities = 15/71 (21%), Positives = 40/71 (56%) Query: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERA 200 T ++++ +EE D G+ ++ E + ED+ +DE D+D D +D++ ++ ++ Sbjct: 220 TRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDED 279 Query: 201 EARKKTTEKQS 211 + ++ E+++ Sbjct: 280 DEDEEDGEEEN 290 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 53.1 bits (126), Expect = 1e-06 Identities = 46/157 (29%), Positives = 70/157 (44%), Gaps = 18/157 (11%) Query: 67 PNGQDLGENSRVA-RLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQY-------RYIKL 118 P+ G+ R+ DE +EE R + D + DPK R ++L Sbjct: 970 PDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLEL 1029 Query: 119 QNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSG---AEIEDDDEEGFDDE 175 +G + LS + +T++EEE E EEEEEDDD+D E E+DDE+ E Sbjct: 1030 DSGGEEDEKESLSEEQ----ESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSE 1085 Query: 176 DEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSA 212 DE D D E+ + + +AEA + +S+ Sbjct: 1086 ASEKDEGDSD---EEETVSIVTSKAEATSSSESSESS 1119 Score = 36.2 bits (82), Expect = 0.18 Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 20/165 (12%) Query: 84 DESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYI-----KLQNGLQALLISDLSNMEGKTG 138 DESE + +LS A + + + SD ++ I + + ++ S+ + + Sbjct: 1072 DESENDDEDTALSEASEKD--EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSP 1129 Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHD--------DDLDTED 190 ++++DEEE EEEE+++E+ E G +D ++ +E D L E Sbjct: 1130 SSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGME- 1188 Query: 191 NELEELEERAEARKKTTEKQSAAALCVGVGSFAD---PDDLPGLA 232 E ++E A A ++ L VGV AD P + PGL+ Sbjct: 1189 -EEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLS 1232 >gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A [Homo sapiens] Length = 249 Score = 52.8 bits (125), Expect = 2e-06 Identities = 34/89 (38%), Positives = 53/89 (59%), Gaps = 11/89 (12%) Query: 131 SNMEGKTGNTTDDEEEEEVEEEEED-------DDEDSGAEIEDDDEEGFDDEDEFDDEHD 183 S+ EG D+EE+E+ EE +ED +DED E E++D G ++EDE + +D Sbjct: 158 SDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDE-EGYND 216 Query: 184 DDLDTEDNELEEL--EERAEARKKTTEKQ 210 ++D E++E EEL EER + RK+ E + Sbjct: 217 GEVDDEEDE-EELGEEERGQKRKREPEDE 244 Score = 33.5 bits (75), Expect = 1.2 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 7/55 (12%) Query: 163 EIEDDDEEGF----DDEDEFDDEHDDDLD---TEDNELEELEERAEARKKTTEKQ 210 E D D EG+ DDE+E +DE + D D ED E E+ EE E + E++ Sbjct: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 Score = 33.1 bits (74), Expect = 1.6 Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 9/53 (16%) Query: 142 DDEEEEEVEEEEEDDDE---DSGAEIEDDDEEGFDDE------DEFDDEHDDD 185 ++ EEE+V EEE+D+E D + E+D+EE ++E E +DE +DD Sbjct: 196 EEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248 >gi|42740903 MTERF domain containing 2 [Homo sapiens] Length = 381 Score = 52.4 bits (124), Expect = 2e-06 Identities = 25/66 (37%), Positives = 44/66 (66%), Gaps = 4/66 (6%) Query: 130 LSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTE 189 L+ E ++ ++T D++ ++E+E+DDDE E D+D+ DD+DE DDE +D+ + E Sbjct: 320 LAREEEESESSTSDDKRASLDEDEDDDDE----EDNDEDDNDEDDDDEDDDEAEDNDEDE 375 Query: 190 DNELEE 195 D++ EE Sbjct: 376 DDDEEE 381 Score = 47.8 bits (112), Expect = 6e-05 Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 2/59 (3%) Query: 145 EEEEVEEEEEDDDEDSGAEIEDDDEEGFDDED--EFDDEHDDDLDTEDNELEELEERAE 201 EEEE E DD S E EDDD+E +DED + DD+ +DD + EDN+ +E ++ E Sbjct: 323 EEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381 Score = 46.6 bits (109), Expect = 1e-04 Identities = 21/56 (37%), Positives = 37/56 (66%), Gaps = 1/56 (1%) Query: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHD 183 S+ S + K + +DE++++ E+ +EDD+++ + EDDDE +DEDE DDE + Sbjct: 327 SESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDD-EDDDEAEDNDEDEDDDEEE 381 Score = 33.9 bits (76), Expect = 0.92 Identities = 15/58 (25%), Positives = 32/58 (55%) Query: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 T EE + ++ ++E+S + DD D++++ DDE D+D D D + ++ ++ Sbjct: 308 TSVEEFQVFKKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDD 365 Score = 32.0 bits (71), Expect = 3.5 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 6/52 (11%) Query: 151 EEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEA 202 EEEE + S DD+ DEDE DD+ +D+ + +++E ++ E+ EA Sbjct: 323 EEEESESSTS------DDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEA 368 >gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens] Length = 302 Score = 52.4 bits (124), Expect = 2e-06 Identities = 29/65 (44%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED 176 N LQ L+ D+ + EG + DD++ +E EEE ED DED G E EDDDE +ED Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297 Query: 177 EFDDE 181 E +D+ Sbjct: 298 EGEDD 302 Score = 40.8 bits (94), Expect = 0.007 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 2/48 (4%) Query: 156 DDEDSGAEIEDDDEEGFDDEDEFDD--EHDDDLDTEDNELEELEERAE 201 DDE+ G + +DDD++G + E+E +D E D+D ED + +E EE E Sbjct: 249 DDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEE 296 Score = 37.0 bits (84), Expect = 0.11 Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%) Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 ++++EE +D+D + D+ EE +D DE D++ ++ D +D+E EE EE Sbjct: 247 DMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEE-DEDDDEGEEGEE 296 Score = 36.6 bits (83), Expect = 0.14 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 5/51 (9%) Query: 150 EEEEEDDDE-----DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 EE EDDD+ D G E +D +EG +DE E D++ D+ + E++E E+ Sbjct: 251 EEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEEDEGED 301 Score = 32.3 bits (72), Expect = 2.7 Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 8/63 (12%) Query: 143 DEEEEEVEEEEEDDDEDSGAEI----EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 D +E+EE +DD + + + DDEEG +D+D+ D DDD D + ELE+++E Sbjct: 221 DAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDD-D---DDDGDEGEEELEDIDE 276 Query: 199 RAE 201 E Sbjct: 277 GDE 279 >gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens] Length = 302 Score = 52.4 bits (124), Expect = 2e-06 Identities = 29/65 (44%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED 176 N LQ L+ D+ + EG + DD++ +E EEE ED DED G E EDDDE +ED Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297 Query: 177 EFDDE 181 E +D+ Sbjct: 298 EGEDD 302 Score = 40.8 bits (94), Expect = 0.007 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 2/48 (4%) Query: 156 DDEDSGAEIEDDDEEGFDDEDEFDD--EHDDDLDTEDNELEELEERAE 201 DDE+ G + +DDD++G + E+E +D E D+D ED + +E EE E Sbjct: 249 DDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEE 296 Score = 37.0 bits (84), Expect = 0.11 Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%) Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 ++++EE +D+D + D+ EE +D DE D++ ++ D +D+E EE EE Sbjct: 247 DMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEE-DEDDDEGEEGEE 296 Score = 36.6 bits (83), Expect = 0.14 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 5/51 (9%) Query: 150 EEEEEDDDE-----DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 EE EDDD+ D G E +D +EG +DE E D++ D+ + E++E E+ Sbjct: 251 EEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEEDEGED 301 Score = 32.3 bits (72), Expect = 2.7 Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 8/63 (12%) Query: 143 DEEEEEVEEEEEDDDEDSGAEI----EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 D +E+EE +DD + + + DDEEG +D+D+ D DDD D + ELE+++E Sbjct: 221 DAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDD-D---DDDGDEGEEELEDIDE 276 Query: 199 RAE 201 E Sbjct: 277 GDE 279 >gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens] Length = 302 Score = 52.4 bits (124), Expect = 2e-06 Identities = 29/65 (44%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED 176 N LQ L+ D+ + EG + DD++ +E EEE ED DED G E EDDDE +ED Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297 Query: 177 EFDDE 181 E +D+ Sbjct: 298 EGEDD 302 Score = 40.8 bits (94), Expect = 0.007 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 2/48 (4%) Query: 156 DDEDSGAEIEDDDEEGFDDEDEFDD--EHDDDLDTEDNELEELEERAE 201 DDE+ G + +DDD++G + E+E +D E D+D ED + +E EE E Sbjct: 249 DDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEE 296 Score = 37.0 bits (84), Expect = 0.11 Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%) Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 ++++EE +D+D + D+ EE +D DE D++ ++ D +D+E EE EE Sbjct: 247 DMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEE-DEDDDEGEEGEE 296 Score = 36.6 bits (83), Expect = 0.14 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 5/51 (9%) Query: 150 EEEEEDDDE-----DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 EE EDDD+ D G E +D +EG +DE E D++ D+ + E++E E+ Sbjct: 251 EEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEEDEGED 301 Score = 32.3 bits (72), Expect = 2.7 Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 8/63 (12%) Query: 143 DEEEEEVEEEEEDDDEDSGAEI----EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198 D +E+EE +DD + + + DDEEG +D+D+ D DDD D + ELE+++E Sbjct: 221 DAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDD-D---DDDGDEGEEELEDIDE 276 Query: 199 RAE 201 E Sbjct: 277 GDE 279 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 52.0 bits (123), Expect = 3e-06 Identities = 56/221 (25%), Positives = 93/221 (42%), Gaps = 59/221 (26%) Query: 25 AALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC--SCPDLQPNGQDLGE--NSRVAR 80 AAL +ET R + ++ F + +NK++ + D N QD GE + V Sbjct: 2245 AALKPLETLSRIVNQPSSL-FGSKSASSKNKSEQDAQGASQDSSSNQQDPGEPGEAEVQE 2303 Query: 81 LGADESEEEGRRGSLSN----------AGDPEIVKSPSDPKQYRYIKLQNGLQALLISDL 130 D ++ E G + + AG PE++ S ++++N L+ L I +L Sbjct: 2304 EDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQE-------MQVENELEDL-IDEL 2355 Query: 131 SNMEGKTGNTT-------DDEEEEEV-----------------------------EEEEE 154 +G +GN+T +DE +E+V +EEE Sbjct: 2356 LERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEH 2415 Query: 155 DDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 +EDS ED+D+ ++E+E +DE DD D E E +E Sbjct: 2416 TQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDE 2456 Score = 47.8 bits (112), Expect = 6e-05 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 17/118 (14%) Query: 78 VARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKT 137 V+R G DES+E D + ++PS+ Q + LQA ++ ++ + Sbjct: 2369 VSRSGEDESQE-----------DVLMDEAPSNLSQ------ASTLQANREDSMNILDPED 2411 Query: 138 GNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195 EE+ E+EDD +D E E+D+E+ +D++ + + DDD D + EL+E Sbjct: 2412 EEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDE 2469 >gi|18093112 ABT1-associated protein [Homo sapiens] Length = 851 Score = 52.0 bits (123), Expect = 3e-06 Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 12/129 (9%) Query: 74 ENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNM 133 E + + D S EE +R ++G EIVKSP ++Q+ +Q ++ D Sbjct: 168 EKKNIVQHTTDSSLEEKQR--TLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGY 225 Query: 134 EGKTGNTTDDEEEEEVEEE---EEDDDEDSGAEIE-------DDDEEGFDDEDEFDDEHD 183 E T D++ E + E E DE+S EI DDD D+E++ D+E D Sbjct: 226 ENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEED 285 Query: 184 DDLDTEDNE 192 +D D+ED++ Sbjct: 286 EDEDSEDDD 294 Score = 35.4 bits (80), Expect = 0.31 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 16/104 (15%) Query: 134 EGKTGNTTDDEEEEEVEEE--EEDDDEDSG-------------AEIEDDDEEGFDDEDEF 178 +G + +DE+EEE E+E E+DD DSG +E EDD + F +E F Sbjct: 270 DGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGF 329 Query: 179 DDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSF 222 + +LD + +E+ R ++ A L SF Sbjct: 330 EHAW-RELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSF 372 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,635,390 Number of Sequences: 37866 Number of extensions: 2252486 Number of successful extensions: 33166 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 485 Number of HSP's successfully gapped in prelim test: 313 Number of HSP's that attempted gapping in prelim test: 13823 Number of HSP's gapped (non-prelim): 8084 length of query: 1151 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1038 effective length of database: 13,968,660 effective search space: 14499469080 effective search space used: 14499469080 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.