Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help
Name: IDE Sequence: fasta or formatted (1019aa) NCBI GI: 155969707
Description:

insulin-degrading enzyme

Referenced in:

Peptide-processing Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         62           2
 C cysteine            1.4         14           1
 D aspartate           4.6         47           2
 E glutamate           8.9         91           2
 F phenylalanine       5.5         56           2
 G glycine             4.6         47           2
 H histidine           3.2         33           1
 I isoleucine          5.7         58           2
 K lysine              7.6         77           2
 L leucine            11.4        116           2
 M methionine          2.5         25           1
 N asparagine          4.7         48           2
 P proline             5.8         59           3
 Q glutamine           4.2         43           2
 R arginine            4.5         46           2
 S serine              5.0         51           2
 T threonine           4.2         43           2
 V valine              4.7         48           2
 W tryptophan          1.0         10           1
 Y tyrosine            4.4         45           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   insulin-degrading enzyme 
NRD1                  0.253   nardilysin isoform a 
NRD1                  0.251   nardilysin isoform b 
PMPCB                 0.009   mitochondrial processing peptidase beta subunit prec...
UQCRC1                0.009   ubiquinol-cytochrome c reductase core protein I [Hom...
PMPCA                 0.007   peptidase (mitochondrial processing) alpha 
PITRM1                0.006   metalloprotease 1 
ZNF263                0.003   zinc finger protein 263 
NPR1                  0.003   natriuretic peptide receptor 1 
TTK                   0.002   TTK protein kinase 
DENND2D               0.002   DENN/MADD domain containing 2D 
ANGPTL7               0.002   angiopoietin-like 7 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press