Guide to the Human Genome
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Search of human proteins with 155722998

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|155722998 solute carrier family 4, sodium bicarbonate
transporter-like, member 10 [Homo sapiens]
         (1088 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|155722998 solute carrier family 4, sodium bicarbonate transpo...  2197   0.0  
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp...  1697   0.0  
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp...  1667   0.0  
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans...  1268   0.0  
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans...  1097   0.0  
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans...  1097   0.0  
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo...  1050   0.0  
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap...   984   0.0  
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa...   974   0.0  
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans...   803   0.0  
gi|156071474 solute carrier family 4, anion exchanger, member 2 ...   673   0.0  
gi|157671951 solute carrier family 4, anion exchanger, member 3 ...   657   0.0  
gi|157671953 solute carrier family 4, anion exchanger, member 3 ...   657   0.0  
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H...   563   e-160
gi|14042960 solute carrier family 4 member 11 [Homo sapiens]          224   3e-58
gi|4504487 histidine rich calcium binding protein precursor [Hom...    37   0.13 
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    36   0.23 
gi|13375827 phafin 2 [Homo sapiens]                                    33   1.1  
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    32   2.5  
gi|58331266 WD repeat domain 59 [Homo sapiens]                         32   3.3  
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        32   4.3  
gi|145279222 WD repeat domain 66 [Homo sapiens]                        32   4.3  
gi|239755074 PREDICTED: hypothetical protein [Homo sapiens]            31   5.6  
gi|239749600 PREDICTED: hypothetical protein XP_002347101 [Homo ...    31   5.6  
gi|239743867 PREDICTED: hypothetical protein XP_002342984 [Homo ...    31   5.6  
gi|59710085 hypothetical protein LOC146562 [Homo sapiens]              31   5.6  
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i...    31   7.3  
gi|21493045 A-kinase anchor protein 6 [Homo sapiens]                   31   7.3  
gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens]        30   9.5  
gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens]        30   9.5  

>gi|155722998 solute carrier family 4, sodium bicarbonate
            transporter-like, member 10 [Homo sapiens]
          Length = 1088

 Score = 2197 bits (5693), Expect = 0.0
 Identities = 1088/1088 (100%), Positives = 1088/1088 (100%)

Query: 1    MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRK 60
            MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRK
Sbjct: 1    MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRK 60

Query: 61   SHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTE 120
            SHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTE
Sbjct: 61   SHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTE 120

Query: 121  LDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVL 180
            LDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVL
Sbjct: 121  LDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVL 180

Query: 181  LDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFA 240
            LDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFA
Sbjct: 181  LDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFA 240

Query: 241  DIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDLHFMKKIPPGAE 300
            DIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDLHFMKKIPPGAE
Sbjct: 241  DIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDLHFMKKIPPGAE 300

Query: 301  ASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRS 360
            ASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRS
Sbjct: 301  ASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRS 360

Query: 361  IATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKR 420
            IATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKR
Sbjct: 361  IATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKR 420

Query: 421  KIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCL 480
            KIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCL
Sbjct: 421  KIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCL 480

Query: 481  ASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTG 540
            ASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTG
Sbjct: 481  ASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTG 540

Query: 541  PVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFAS 600
            PVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFAS
Sbjct: 541  PVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFAS 600

Query: 601  LICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISA 660
            LICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISA
Sbjct: 601  LICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISA 660

Query: 661  SDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSR 720
            SDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSR
Sbjct: 661  SDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSR 720

Query: 721  YFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNP 780
            YFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNP
Sbjct: 721  YFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNP 780

Query: 781  WWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMG 840
            WWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMG
Sbjct: 781  WWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMG 840

Query: 841  LPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSIL 900
            LPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSIL
Sbjct: 841  LPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSIL 900

Query: 901  KFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQ 960
            KFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQ
Sbjct: 901  KFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQ 960

Query: 961  MSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDA 1020
            MSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDA
Sbjct: 961  MSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDA 1020

Query: 1021 EKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTALWRNLLITADNSKDKESS 1080
            EKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTALWRNLLITADNSKDKESS
Sbjct: 1021 EKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTALWRNLLITADNSKDKESS 1080

Query: 1081 FPSKSSPS 1088
            FPSKSSPS
Sbjct: 1081 FPSKSSPS 1088


>gi|90403614 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform a [Homo sapiens]
          Length = 1093

 Score = 1697 bits (4395), Expect = 0.0
 Identities = 835/1076 (77%), Positives = 944/1076 (87%), Gaps = 18/1076 (1%)

Query: 17   RNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRD 76
            R DEEAVVD+GGT +IL  H+EKE+LEGHRTL++GV +PLG R+SHR HR  G KHR+R 
Sbjct: 17   RPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRG 75

Query: 77   RERDSGL-EDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWR 135
            R + +   E+G E+ + DTPSQRVQFILGTE+D EEH+PH+LFTELDEIC +EGEDAEW+
Sbjct: 76   RGKGASQGEEGLEALAHDTPSQRVQFILGTEED-EEHVPHELFTELDEICMKEGEDAEWK 134

Query: 136  ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMV 195
            ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSC++NGTVLLDMHAN++EEI+D++
Sbjct: 135  ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLI 194

Query: 196  LDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKN 255
            LDQQ  S  LN+ +R +V EAL+K+HHHQN+KK  N IPIVRSFA++GKKQS+P+ MDK+
Sbjct: 195  LDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKH 254

Query: 256  AGQVVSPQSAPAC-VENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDR 314
             GQ VSPQS P   +E KN V+ E+S VD SKVDLHFMKKIP GAEASN+LVGE++ LDR
Sbjct: 255  -GQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDR 313

Query: 315  TVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVA 374
             +VAFVRLSPAVLL GL EVPIPTRFLFILLGP+GKGQQYHEIGRS+AT+MTDE+FHDVA
Sbjct: 314  PIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVA 373

Query: 375  YKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGE 434
            YKAK+R+DL++GIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK+P VPNG   H E
Sbjct: 374  YKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIE 433

Query: 435  AEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPV 494
             EPHGGHSGPELQRTGR+FGGL+LDIKRKAP++WSD+RDA SLQCLASFLFLYCACMSPV
Sbjct: 434  QEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPV 493

Query: 495  ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCK 554
            ITFGGLLGEATEGRISAIESLFGASMTGIAYSLF GQ LTILGSTGPVLVFEKILFKFCK
Sbjct: 494  ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCK 553

Query: 555  EYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKL 614
            +Y LSYLSLRA IGLWTA LCI+LVATDASSLVCYITRFTEEAFASLICIIFIYEA+EKL
Sbjct: 554  DYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKL 613

Query: 615  FELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECK 674
              L+E YPI+MH+ L+ L+ Y C C  P NP+N TL+ W++ NI  +++ W NLTVSEC+
Sbjct: 614  IHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQ 673

Query: 675  SLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFA 734
             +HGE++G ACGH  PY PDVLFWS ILFF+T  LS+TLK FKTSRYFPT+VRS+VSDFA
Sbjct: 674  EMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFA 733

Query: 735  VFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLC 794
            VFLTI  MV+ID+ IG+PSPKLQVPSVFKPTRDDRGW + P+GPNPWWTVIAAIIPALLC
Sbjct: 734  VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLC 793

Query: 795  TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITH 854
            TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVA+MLGVCSIMGLPWFVAATVLSITH
Sbjct: 794  TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITH 853

Query: 855  VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLY 914
            VNSLKLESECSAPGEQPKFLGIREQRVTGLMIF+LMG SVFMT+ILKFIPMPVLYGVFLY
Sbjct: 854  VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLY 913

Query: 915  MGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSR 974
            MG SSL+GIQFFDR+KLF MPAKHQPDFIYLRHVPLRKVHLFT+IQ++CL LLW+IK S 
Sbjct: 914  MGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASP 973

Query: 975  AAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEK--EEEQSMLAME 1032
            AAIVFPMMVLALVFVRK+MDL F+KRELSWLDDLMPESKKKKL+DA+K  +EE+    M 
Sbjct: 974  AAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEEAEKML 1033

Query: 1033 DEGTVQLPLEGH-----------YRDDPSVINISDEMSKTALWRNLLITADNSKDK 1077
            + G  + PLE              R DPS INISDEM KT +W+ L + + N+K+K
Sbjct: 1034 EIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALSMNSGNAKEK 1089


>gi|90568034 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform b [Homo sapiens]
          Length = 1044

 Score = 1667 bits (4317), Expect = 0.0
 Identities = 815/1019 (79%), Positives = 915/1019 (89%), Gaps = 8/1019 (0%)

Query: 17   RNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRD 76
            R DEEAVVD+GGT +IL  H+EKE+LEGHRTL++GV +PLG R+SHR HR  G KHR+R 
Sbjct: 17   RPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRG 75

Query: 77   RERDSGL-EDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWR 135
            R + +   E+G E+ + DTPSQRVQFILGTE+D EEH+PH+LFTELDEIC +EGEDAEW+
Sbjct: 76   RGKGASQGEEGLEALAHDTPSQRVQFILGTEED-EEHVPHELFTELDEICMKEGEDAEWK 134

Query: 136  ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMV 195
            ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSC++NGTVLLDMHAN++EEI+D++
Sbjct: 135  ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLI 194

Query: 196  LDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKN 255
            LDQQ  S  LN+ +R +V EAL+K+HHHQN+KK  N IPIVRSFA++GKKQS+P+ MDK+
Sbjct: 195  LDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKH 254

Query: 256  AGQVVSPQSAPAC-VENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDR 314
             GQ VSPQS P   +E KN V+ E+S VD SKVDLHFMKKIP GAEASN+LVGE++ LDR
Sbjct: 255  -GQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDR 313

Query: 315  TVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVA 374
             +VAFVRLSPAVLL GL EVPIPTRFLFILLGP+GKGQQYHEIGRS+AT+MTDE+FHDVA
Sbjct: 314  PIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVA 373

Query: 375  YKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGE 434
            YKAK+R+DL++GIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK+P VPNG   H E
Sbjct: 374  YKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIE 433

Query: 435  AEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPV 494
             EPHGGHSGPELQRTGR+FGGL+LDIKRKAP++WSD+RDA SLQCLASFLFLYCACMSPV
Sbjct: 434  QEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPV 493

Query: 495  ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCK 554
            ITFGGLLGEATEGRISAIESLFGASMTGIAYSLF GQ LTILGSTGPVLVFEKILFKFCK
Sbjct: 494  ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCK 553

Query: 555  EYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKL 614
            +Y LSYLSLRA IGLWTA LCI+LVATDASSLVCYITRFTEEAFASLICIIFIYEA+EKL
Sbjct: 554  DYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKL 613

Query: 615  FELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECK 674
              L+E YPI+MH+ L+ L+ Y C C  P NP+N TL+ W++ NI  +++ W NLTVSEC+
Sbjct: 614  IHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQ 673

Query: 675  SLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFA 734
             +HGE++G ACGH  PY PDVLFWS ILFF+T  LS+TLK FKTSRYFPT+VRS+VSDFA
Sbjct: 674  EMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFA 733

Query: 735  VFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLC 794
            VFLTI  MV+ID+ IG+PSPKLQVPSVFKPTRDDRGW + P+GPNPWWTVIAAIIPALLC
Sbjct: 734  VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLC 793

Query: 795  TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITH 854
            TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVA+MLGVCSIMGLPWFVAATVLSITH
Sbjct: 794  TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITH 853

Query: 855  VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLY 914
            VNSLKLESECSAPGEQPKFLGIREQRVTGLMIF+LMG SVFMT+ILKFIPMPVLYGVFLY
Sbjct: 854  VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLY 913

Query: 915  MGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSR 974
            MG SSL+GIQFFDR+KLF MPAKHQPDFIYLRHVPLRKVHLFT+IQ++CL LLW+IK S 
Sbjct: 914  MGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASP 973

Query: 975  AAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAE---KEEEQSMLA 1030
            AAIVFPMMVLALVFVRK+MDL F+KRELSWLDDLMPESKKKKL+DA+   KEEE  +LA
Sbjct: 974  AAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEVIVLA 1032


>gi|134288865 solute carrier family 4, sodium bicarbonate
            cotransporter, member 7 [Homo sapiens]
          Length = 1214

 Score = 1268 bits (3280), Expect = 0.0
 Identities = 627/814 (77%), Positives = 700/814 (85%), Gaps = 13/814 (1%)

Query: 243  GKKQSEPNSMDKNAGQVVSPQSAPACVENKNDV---------SRENSTVDFSKVDLHFMK 293
            G++Q    ++D   G + SPQSAP  ++N             SRENSTVDFSKVD++FM+
Sbjct: 361  GEEQKNEENVDLTPGILASPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDFSKVDMNFMR 420

Query: 294  KIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQ 353
            KIP GAEASN+LVGE++FL+R ++AFVRL+PAVLL GL EVP+PTRFLF+LLGP GK  Q
Sbjct: 421  KIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQ 480

Query: 354  YHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKN 413
            YHEIGRSIATLMTDE+FHDVAYKAKDRNDL+SGIDEFLDQVTVLPPGEWDPSIRIEPPK+
Sbjct: 481  YHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKS 540

Query: 414  VPSQEKRKIPAVPNG-TAAHGEAEPHGGH-SGPELQRTGRIFGGLILDIKRKAPYFWSDF 471
            VPSQEKRKIP   NG T   GE      H +GPELQRTGR+FGGLILDIKRKAP+F SDF
Sbjct: 541  VPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDF 600

Query: 472  RDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQ 531
            +DA SLQCLAS LFLYCACMSPVITFGGLLGEATEGRISAIESLFGAS+TGIAYSLF GQ
Sbjct: 601  KDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQ 660

Query: 532  PLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYIT 591
            PLTILGSTGPVLVFEKIL+KFC++Y LSYLSLR SIGLWT+ LCI+LVATDASSLVCYIT
Sbjct: 661  PLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYIT 720

Query: 592  RFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLK 651
            RFTEEAFA+LICIIFIYEALEKLF+L E Y  NMHN+L+ LT YSC C EP NPSN TL 
Sbjct: 721  RFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNETLA 780

Query: 652  EWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSA 711
            +W++ NI+A +I W NLTVSECK L G ++G ACGH  PY+PDVLFW VILFF+T  LS+
Sbjct: 781  QWKKDNITAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSS 840

Query: 712  TLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGW 771
             LKQFKT RYFPTKVRS +SDFAVFLTI+ MV IDY +G+PSPKL VP  F+PT  +RGW
Sbjct: 841  FLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGW 900

Query: 772  FVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAV 831
             ++PLG NPWWT++ A IPALLCTILIFMDQQITAVIINRKEHKLKKG GYHLDLLMV V
Sbjct: 901  IISPLGDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGV 960

Query: 832  MLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMG 891
            MLGVCS+MGLPWFVAATVLSI+HVNSLK+ESECSAPGEQPKFLGIREQRVTGLMIFILMG
Sbjct: 961  MLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMG 1020

Query: 892  SSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLR 951
             SVFMTS+LKFIPMPVLYGVFLYMG SSLKGIQ FDRIKLF MPAKHQPD IYLR+VPL 
Sbjct: 1021 LSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLW 1080

Query: 952  KVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPE 1011
            KVH+FT+IQ++CL LLW+IKVS AA+VFPMMVLALVFVRKLMDL FTKRELSWLDDLMPE
Sbjct: 1081 KVHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPE 1140

Query: 1012 SKKKKLEDAEK--EEEQSMLAMEDEGTVQLPLEG 1043
            SKKKK +D +K  +EE   +  +D+ TV LP EG
Sbjct: 1141 SKKKKEDDKKKKEKEEAERMLQDDDDTVHLPFEG 1174



 Score =  372 bits (955), Expect = e-102
 Identities = 174/238 (73%), Positives = 209/238 (87%), Gaps = 2/238 (0%)

Query: 19  DEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDR- 77
           DEEAVVD G T S + T FEKE+LE HR ++IGVHVP   ++S RRHRHRGHKH  R R 
Sbjct: 14  DEEAVVDLGKTSSTVNTKFEKEELESHRAVYIGVHVPFS-KESRRRHRHRGHKHHHRRRK 72

Query: 78  ERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRET 137
           +++S  EDGRESPS+DTPSQRVQFILGTEDDDEEHIPHDLFTE+DE+C+R+GE+ EW+ET
Sbjct: 73  DKESDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKET 132

Query: 138 ARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLD 197
           ARWLKFEEDVEDGG+RWSKPYVATLSLHSLFELRSCILNGTV+LDM A+TL+EIADMVLD
Sbjct: 133 ARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLD 192

Query: 198 QQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKN 255
             ++SGQL+E +R  V EAL+K+HHHQN+K+ T+RIP+VRSFADIGKK S+P+ +++N
Sbjct: 193 NMIASGQLDESIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERN 250


>gi|197927160 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 3 [Homo sapiens]
          Length = 1094

 Score = 1097 bits (2836), Expect = 0.0
 Identities = 571/1043 (54%), Positives = 733/1043 (70%), Gaps = 56/1043 (5%)

Query: 19   DEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRE 78
            ++EAV+DRG   S LK   ++E++EGH T++IGVHVP   R+  R  R  GHK +K ++E
Sbjct: 2    EDEAVLDRGA--SFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKK-EKE 58

Query: 79   R-------DSGLEDGRES------PSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEIC 125
            R        S +E+  ES      P     ++R++FILG EDD     P  LFTELDE+ 
Sbjct: 59   RISENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPA--PPQLFTELDELL 116

Query: 126  WREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHA 185
              +G++ EW+ETARW+KFEE VE GGERWSKP+VATLSLHSLFELR+C+  G+++LD  A
Sbjct: 117  AVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREA 176

Query: 186  NTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKK 245
            ++L ++ +M++D Q+ +G L  +++ +V   L+++H HQ +K        +RS ADIGK 
Sbjct: 177  SSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSN------LRSLADIGKT 230

Query: 246  QSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDL---HFMKKIPPGAEAS 302
             S  + M  N         +PA        S  N   D  + D     FMKK+P  AEAS
Sbjct: 231  VSSASRMFTNPDN-----GSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEAS 285

Query: 303  NILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIA 362
            N+LVGE++FLD   +AFVRL  AV+L  L EVP+PTRFLFILLGP GK + YHEIGR+IA
Sbjct: 286  NVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIA 345

Query: 363  TLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK- 421
            TLM+DEVFHD+AYKAKDR+DL++GIDEFLD+V VLPPGEWDP+IRIEPPK++PS +KRK 
Sbjct: 346  TLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKN 405

Query: 422  IPAVPNGTAAHGEAEPHGGHSG------PELQRTGRIFGGLILDIKRKAPYFWSDFRDAF 475
            + +       +G+    GGH G       ELQRTGR  GGLI DIKRKAP+F SDF DA 
Sbjct: 406  MYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDAL 465

Query: 476  SLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTI 535
            ++Q L++ LF+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LF GQPLTI
Sbjct: 466  NIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTI 525

Query: 536  LGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTE 595
            L STGPVLVFE++LF F K+    YL  R  IGLW+A LC+ILVATDAS LV Y TRFTE
Sbjct: 526  LSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTE 585

Query: 596  EAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSN------GT 649
            E F+SLI  IFIY+A +K+ +L++ YPIN +  +   T +SC CV P +P+N       T
Sbjct: 586  EGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP-DPANISISNDTT 644

Query: 650  LKEWRESNISASDII------WENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILF 703
            L       +S++D+       W  L+  EC    G  VG  C     +VPD+   S ILF
Sbjct: 645  LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILF 700

Query: 704  FSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFK 763
              T T S  LK+FKTS YFPT  R ++SDFA+ L+IL   +ID  +G+ +PKL VPS FK
Sbjct: 701  LGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFK 760

Query: 764  PTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYH 823
            PT  +RGWFV P G NPWW  +AA IPALL TILIFMDQQITAVI+NRKEHKLKKG GYH
Sbjct: 761  PTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYH 820

Query: 824  LDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTG 883
            LDL  VA+++ +CS+M LPW+VAATV+SI H++SLK+E+E SAPGEQPKFLG+REQRVTG
Sbjct: 821  LDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTG 880

Query: 884  LMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFI 943
             ++FIL G SVFM  ILKFIPMPVLYGVFLYMG +SL G+QF DR+KL  MP KHQPDFI
Sbjct: 881  TLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFI 940

Query: 944  YLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELS 1003
            YLRHVPLR+VHLFT +Q+ CL LLWI+K + AAI+FP+M+LALV VRK MD LF++ +LS
Sbjct: 941  YLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLS 1000

Query: 1004 WLDDLMPESKKKKLEDAEKEEEQ 1026
            +LDD++PE  KKK ED +K++++
Sbjct: 1001 FLDDVIPEKDKKKKEDEKKKKKK 1023


>gi|148596928 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 1 [Homo sapiens]
          Length = 1079

 Score = 1097 bits (2836), Expect = 0.0
 Identities = 571/1043 (54%), Positives = 733/1043 (70%), Gaps = 56/1043 (5%)

Query: 19   DEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRE 78
            ++EAV+DRG   S LK   ++E++EGH T++IGVHVP   R+  R  R  GHK +K ++E
Sbjct: 2    EDEAVLDRGA--SFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKK-EKE 58

Query: 79   R-------DSGLEDGRES------PSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEIC 125
            R        S +E+  ES      P     ++R++FILG EDD     P  LFTELDE+ 
Sbjct: 59   RISENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPA--PPQLFTELDELL 116

Query: 126  WREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHA 185
              +G++ EW+ETARW+KFEE VE GGERWSKP+VATLSLHSLFELR+C+  G+++LD  A
Sbjct: 117  AVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREA 176

Query: 186  NTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKK 245
            ++L ++ +M++D Q+ +G L  +++ +V   L+++H HQ +K        +RS ADIGK 
Sbjct: 177  SSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSN------LRSLADIGKT 230

Query: 246  QSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDL---HFMKKIPPGAEAS 302
             S  + M  N         +PA        S  N   D  + D     FMKK+P  AEAS
Sbjct: 231  VSSASRMFTNPDN-----GSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEAS 285

Query: 303  NILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIA 362
            N+LVGE++FLD   +AFVRL  AV+L  L EVP+PTRFLFILLGP GK + YHEIGR+IA
Sbjct: 286  NVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIA 345

Query: 363  TLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK- 421
            TLM+DEVFHD+AYKAKDR+DL++GIDEFLD+V VLPPGEWDP+IRIEPPK++PS +KRK 
Sbjct: 346  TLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKN 405

Query: 422  IPAVPNGTAAHGEAEPHGGHSG------PELQRTGRIFGGLILDIKRKAPYFWSDFRDAF 475
            + +       +G+    GGH G       ELQRTGR  GGLI DIKRKAP+F SDF DA 
Sbjct: 406  MYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDAL 465

Query: 476  SLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTI 535
            ++Q L++ LF+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LF GQPLTI
Sbjct: 466  NIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTI 525

Query: 536  LGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTE 595
            L STGPVLVFE++LF F K+    YL  R  IGLW+A LC+ILVATDAS LV Y TRFTE
Sbjct: 526  LSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTE 585

Query: 596  EAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSN------GT 649
            E F+SLI  IFIY+A +K+ +L++ YPIN +  +   T +SC CV P +P+N       T
Sbjct: 586  EGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP-DPANISISNDTT 644

Query: 650  LKEWRESNISASDII------WENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILF 703
            L       +S++D+       W  L+  EC    G  VG  C     +VPD+   S ILF
Sbjct: 645  LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILF 700

Query: 704  FSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFK 763
              T T S  LK+FKTS YFPT  R ++SDFA+ L+IL   +ID  +G+ +PKL VPS FK
Sbjct: 701  LGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFK 760

Query: 764  PTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYH 823
            PT  +RGWFV P G NPWW  +AA IPALL TILIFMDQQITAVI+NRKEHKLKKG GYH
Sbjct: 761  PTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYH 820

Query: 824  LDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTG 883
            LDL  VA+++ +CS+M LPW+VAATV+SI H++SLK+E+E SAPGEQPKFLG+REQRVTG
Sbjct: 821  LDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTG 880

Query: 884  LMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFI 943
             ++FIL G SVFM  ILKFIPMPVLYGVFLYMG +SL G+QF DR+KL  MP KHQPDFI
Sbjct: 881  TLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFI 940

Query: 944  YLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELS 1003
            YLRHVPLR+VHLFT +Q+ CL LLWI+K + AAI+FP+M+LALV VRK MD LF++ +LS
Sbjct: 941  YLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLS 1000

Query: 1004 WLDDLMPESKKKKLEDAEKEEEQ 1026
            +LDD++PE  KKK ED +K++++
Sbjct: 1001 FLDDVIPEKDKKKKEDEKKKKKK 1023


>gi|4507025 solute carrier family 4, sodium bicarbonate cotransporter,
            member 4 isoform 2 [Homo sapiens]
          Length = 1035

 Score = 1050 bits (2714), Expect = 0.0
 Identities = 537/953 (56%), Positives = 684/953 (71%), Gaps = 40/953 (4%)

Query: 96   SQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWS 155
            ++R++FILG EDD     P  LFTELDE+   +G++ EW+ETARW+KFEE VE GGERWS
Sbjct: 45   AERIRFILGEEDDSPA--PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWS 102

Query: 156  KPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHE 215
            KP+VATLSLHSLFELR+C+  G+++LD  A++L ++ +M++D Q+ +G L  +++ +V  
Sbjct: 103  KPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTY 162

Query: 216  ALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDV 275
             L+++H HQ +K        +RS ADIGK  S  + M  N         +PA        
Sbjct: 163  TLLRKHRHQTKKSN------LRSLADIGKTVSSASRMFTNPDN-----GSPAMTHRNLTS 211

Query: 276  SRENSTVDFSKVDL---HFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLA 332
            S  N   D  + D     FMKK+P  AEASN+LVGE++FLD   +AFVRL  AV+L  L 
Sbjct: 212  SSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALT 271

Query: 333  EVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLD 392
            EVP+PTRFLFILLGP GK + YHEIGR+IATLM+DEVFHD+AYKAKDR+DL++GIDEFLD
Sbjct: 272  EVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLD 331

Query: 393  QVTVLPPGEWDPSIRIEPPKNVPSQEKRK-IPAVPNGTAAHGEAEPHGGHSG------PE 445
            +V VLPPGEWDP+IRIEPPK++PS +KRK + +       +G+    GGH G       E
Sbjct: 332  EVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEE 391

Query: 446  LQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEAT 505
            LQRTGR  GGLI DIKRKAP+F SDF DA ++Q L++ LF+Y A ++  ITFGGLLG+AT
Sbjct: 392  LQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDAT 451

Query: 506  EGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRA 565
            +     +ES  G +++G  + LF GQPLTIL STGPVLVFE++LF F K+    YL  R 
Sbjct: 452  DNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRL 511

Query: 566  SIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINM 625
             IGLW+A LC+ILVATDAS LV Y TRFTEE F+SLI  IFIY+A +K+ +L++ YPIN 
Sbjct: 512  WIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINS 571

Query: 626  HNDLELLTQYSCNCVEPHNPSN------GTLKEWRESNISASDII------WENLTVSEC 673
            +  +   T +SC CV P +P+N       TL       +S++D+       W  L+  EC
Sbjct: 572  NFKVGYNTLFSCTCVPP-DPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKEC 630

Query: 674  KSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDF 733
                G  VG  C     +VPD+   S ILF  T T S  LK+FKTS YFPT  R ++SDF
Sbjct: 631  SKYGGNLVGNNCN----FVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDF 686

Query: 734  AVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALL 793
            A+ L+IL   +ID  +G+ +PKL VPS FKPT  +RGWFV P G NPWW  +AA IPALL
Sbjct: 687  AIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALL 746

Query: 794  CTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSIT 853
             TILIFMDQQITAVI+NRKEHKLKKG GYHLDL  VA+++ +CS+M LPW+VAATV+SI 
Sbjct: 747  VTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIA 806

Query: 854  HVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFL 913
            H++SLK+E+E SAPGEQPKFLG+REQRVTG ++FIL G SVFM  ILKFIPMPVLYGVFL
Sbjct: 807  HIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFL 866

Query: 914  YMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVS 973
            YMG +SL G+QF DR+KL  MP KHQPDFIYLRHVPLR+VHLFT +Q+ CL LLWI+K +
Sbjct: 867  YMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKST 926

Query: 974  RAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ 1026
             AAI+FP+M+LALV VRK MD LF++ +LS+LDD++PE  KKK ED +K++++
Sbjct: 927  VAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKK 979


>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
          Length = 1121

 Score =  984 bits (2544), Expect = 0.0
 Identities = 521/1089 (47%), Positives = 705/1089 (64%), Gaps = 99/1089 (9%)

Query: 39   KEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQR 98
            K D +GH +    VH  L   +  +     G     +D   D  L     SP+    +++
Sbjct: 44   KTDQKGHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMD--LISRTRSPA----AEQ 97

Query: 99   VQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPY 158
            +Q ILG ED+        LFTE+D +   +G+  EW+E+ARW+KFEE VE+GGERWSKP+
Sbjct: 98   LQDILGEEDEAPNPT---LFTEMDTL-QHDGDQMEWKESARWIKFEEKVEEGGERWSKPH 153

Query: 159  VATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALM 218
            V+TLSLHSLFELR+C+  GTVLLD+ + +L +I D V+++Q+  G L  ++R RV   L+
Sbjct: 154  VSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLL 213

Query: 219  KQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRE 278
            ++H HQ +K      PI RS ADIGK  S  N          SP + P+   +  D+   
Sbjct: 214  RRHRHQTKK------PIHRSLADIGKSVSTTNRSPAR-----SPGAGPSLHHSTEDLRMR 262

Query: 279  NS-------------------TVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAF 319
             S                   T +  +    FMKKIP  +EASN+LVGE++FLD+  +AF
Sbjct: 263  QSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAF 322

Query: 320  VRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKD 379
            VRL  + +L G+ EVP+PTRFLFILLGP G+ + Y+EIGR+IATLM D++F DVAYKA++
Sbjct: 323  VRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARN 382

Query: 380  RNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIP------AVPNGTAAHG 433
            R DL++GIDEFLD+V VLPPGEWDP+IRIEPPK VPS +KRK           NG+   G
Sbjct: 383  REDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGG 442

Query: 434  EAEPHGGHSG---------------------------------PELQRTGRIFGGLILDI 460
               P GG+ G                                  EL  TGR FGGL LDI
Sbjct: 443  GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDI 502

Query: 461  KRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASM 520
            KRK P+F SDF D F +Q +++ LF+Y  C++  ITFGGLLG+AT+     +ES  G +M
Sbjct: 503  KRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAM 562

Query: 521  TGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVA 580
             G  + LF GQPL IL STGP+L+FEK+LF F K  GL Y+  R  IGL +A  C+ILVA
Sbjct: 563  AGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVA 622

Query: 581  TDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCV 640
            TDAS ++ YITRFTEE F++LI  IFIY+A++K+    + YPINM      +T Y C CV
Sbjct: 623  TDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECV 682

Query: 641  EPHNPS----NGTLKEWRESNISASDII------WENLTVSECKSLHGEYVGRACGHDHP 690
             P   +    N +     ++N S  +++      W  L+  EC S  G  +G +C     
Sbjct: 683  APDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSC----K 738

Query: 691  YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIG 750
            ++PD+   S ILFF T +++ TLK+FK SRYFPTKVR++V+DF++  +IL    ID   G
Sbjct: 739  FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFG 798

Query: 751  IPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN 810
            + +PKL VPSV KPTR DRGWFV P G NPWW   A+I+PALL TILIFMDQQITAVI+N
Sbjct: 799  LETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVN 858

Query: 811  RKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ 870
            RKE+KLKK  GYHLDL  V +++ +CS MGLPW+VAATV+SI H++SLK+E+E SAPGEQ
Sbjct: 859  RKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQ 918

Query: 871  PKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIK 930
            P+FLG+REQRVTG+++FIL G SVF+  ILK IP+PVLYGVFLYMG +SL GIQF++R K
Sbjct: 919  PQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQFWERCK 978

Query: 931  LFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVR 990
            LF MPAKHQPD  +LRHVPLR++HLFT++Q+ CL +LWI+K + AAI+FP+M+L L+ VR
Sbjct: 979  LFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVR 1038

Query: 991  KLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDE------GTVQLPLEGH 1044
            +L+D +F++ +L+W+D+++PE +KK+ +   K ++ +    ++E        +++P+E  
Sbjct: 1039 RLLDFIFSQHDLAWIDNILPEKEKKETDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESV 1098

Query: 1045 YRDDPSVIN 1053
              D  + I+
Sbjct: 1099 QSDPQNGIH 1107


>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
            sapiens]
          Length = 1137

 Score =  974 bits (2517), Expect = 0.0
 Identities = 521/1105 (47%), Positives = 705/1105 (63%), Gaps = 115/1105 (10%)

Query: 39   KEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQR 98
            K D +GH +    VH  L   +  +     G     +D   D  L     SP+    +++
Sbjct: 44   KTDQKGHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMD--LISRTRSPA----AEQ 97

Query: 99   VQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPY 158
            +Q ILG ED+        LFTE+D +   +G+  EW+E+ARW+KFEE VE+GGERWSKP+
Sbjct: 98   LQDILGEEDEAPNPT---LFTEMDTL-QHDGDQMEWKESARWIKFEEKVEEGGERWSKPH 153

Query: 159  VATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALM 218
            V+TLSLHSLFELR+C+  GTVLLD+ + +L +I D V+++Q+  G L  ++R RV   L+
Sbjct: 154  VSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLL 213

Query: 219  KQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRE 278
            ++H HQ +K      PI RS ADIGK  S  N          SP + P+   +  D+   
Sbjct: 214  RRHRHQTKK------PIHRSLADIGKSVSTTNRSPAR-----SPGAGPSLHHSTEDLRMR 262

Query: 279  NS-------------------TVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAF 319
             S                   T +  +    FMKKIP  +EASN+LVGE++FLD+  +AF
Sbjct: 263  QSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAF 322

Query: 320  VRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKD 379
            VRL  + +L G+ EVP+PTRFLFILLGP G+ + Y+EIGR+IATLM D++F DVAYKA++
Sbjct: 323  VRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARN 382

Query: 380  RNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIP------AVPNGTAAHG 433
            R DL++GIDEFLD+V VLPPGEWDP+IRIEPPK VPS +KRK           NG+   G
Sbjct: 383  REDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGG 442

Query: 434  EAEPHGGHSG---------------------------------PELQRTGRIFGGLILDI 460
               P GG+ G                                  EL  TGR FGGL LDI
Sbjct: 443  GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDI 502

Query: 461  KRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASM 520
            KRK P+F SDF D F +Q +++ LF+Y  C++  ITFGGLLG+AT+     +ES  G +M
Sbjct: 503  KRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAM 562

Query: 521  TGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVA 580
             G  + LF GQPL IL STGP+L+FEK+LF F K  GL Y+  R  IGL +A  C+ILVA
Sbjct: 563  AGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVA 622

Query: 581  TDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCV 640
            TDAS ++ YITRFTEE F++LI  IFIY+A++K+    + YPINM      +T Y C CV
Sbjct: 623  TDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECV 682

Query: 641  EPHNPS----NGTLKEWRESNISASDII------WENLTVSECKSLHGEYVGRACGHDHP 690
             P   +    N +     ++N S  +++      W  L+  EC S  G  +G +C     
Sbjct: 683  APDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSC----K 738

Query: 691  YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIG 750
            ++PD+   S ILFF T +++ TLK+FK SRYFPTKVR++V+DF++  +IL    ID   G
Sbjct: 739  FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFG 798

Query: 751  IPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN 810
            + +PKL VPSV KPTR DRGWFV P G NPWW   A+I+PALL TILIFMDQQITAVI+N
Sbjct: 799  LETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVN 858

Query: 811  RKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ 870
            RKE+KLKK  GYHLDL  V +++ +CS MGLPW+VAATV+SI H++SLK+E+E SAPGEQ
Sbjct: 859  RKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQ 918

Query: 871  PKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQ------ 924
            P+FLG+REQRVTG+++FIL G SVF+  ILK IP+PVLYGVFLYMG +SL GIQ      
Sbjct: 919  PQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGS 978

Query: 925  ----------FFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSR 974
                      F++R KLF MPAKHQPD  +LRHVPLR++HLFT++Q+ CL +LWI+K + 
Sbjct: 979  EFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTV 1038

Query: 975  AAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDE 1034
            AAI+FP+M+L L+ VR+L+D +F++ +L+W+D+++PE +KK+ +   K ++ +    ++E
Sbjct: 1039 AAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKETDKKRKRKKGAHEDCDEE 1098

Query: 1035 ------GTVQLPLEGHYRDDPSVIN 1053
                    +++P+E    D  + I+
Sbjct: 1099 PQFPPPSVIKIPMESVQSDPQNGIH 1123


>gi|151101449 solute carrier family 4, sodium bicarbonate
            cotransporter, member 9 [Homo sapiens]
          Length = 959

 Score =  803 bits (2075), Expect = 0.0
 Identities = 454/993 (45%), Positives = 617/993 (62%), Gaps = 74/993 (7%)

Query: 78   ERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEIC-WREGEDAEWRE 136
            E DS  + G   PS D PS      LG   D        LF +L+E+  W +    EWRE
Sbjct: 24   ELDSNPDPGT-GPSPDGPSDTESKELGVPKDPL------LFIQLNELLGWPQA--LEWRE 74

Query: 137  TARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVL 196
            T RW+ FEE +E    RWS P+V TL+L SL +LRS +  G VLLD  A +L E+ + V 
Sbjct: 75   TGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVT 134

Query: 197  DQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNA 256
              +     L+ ++R ++   L+++  H NQ   T   P   S        + P     N 
Sbjct: 135  RVE----SLSPELRGQLQALLLQRPQHYNQT--TGTRPCWGS--------THPRKASDN- 179

Query: 257  GQVVSPQSAPACVENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTV 316
                  + AP   + +N + +                K+PPGAEA  +L GEL FL + +
Sbjct: 180  ------EEAPLREQCQNPLRQ----------------KLPPGAEAGTVLAGELGFLAQPL 217

Query: 317  VAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYK 376
             AFVRL   V+L  L EV +P+RF  +LLGP   G+ YHE+GR+ A L++D  F     +
Sbjct: 218  GAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRR 277

Query: 377  AKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKR--------KIPAVPNG 428
            A + +DL++ +D FL++VTVLPPG WDP+ RI PPK +PSQ KR        + PAVP  
Sbjct: 278  ASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPSQQREIRGPAVPRL 337

Query: 429  TAAHGEAEPHGGHS-GPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLY 487
            T+A  +   HG H+  PELQRTGR+FGGLI D++RK P++ SDF DA  LQC ++ L++Y
Sbjct: 338  TSAE-DRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIY 396

Query: 488  CACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEK 547
             A ++  ITFGGLLG+AT+G    +ES  G ++ G A+ L  GQPLTIL STGPVLVFE+
Sbjct: 397  LATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFER 456

Query: 548  ILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFI 607
            +LF F ++Y L YL  R  +G+W AT C++LVAT+AS LV Y TRFTEE F +LI +IFI
Sbjct: 457  LLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFI 516

Query: 608  YEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEW-RESNISASDIIWE 666
            Y+A+ K+  L+  YPI         + Y C C  P     G   +W R       DI+  
Sbjct: 517  YDAVGKMLNLTHTYPIQKPGS----SAYGCLCQYPG--PGGNESQWIRTRPKDRDDIVSM 570

Query: 667  NLTVSECKSLHGEYVGRACGHDHP----YVPDVLFWSVILFFSTVTLSATLKQFKTSRYF 722
            +L +     L      R  GH        VPD+ F+S++LF ++   +  LK  KTSR+F
Sbjct: 571  DLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFF 630

Query: 723  PTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWW 782
            P+ VR  +SDF+  L IL    +D  +G+ +PKL VP  FKPT   RGW V+P G NPWW
Sbjct: 631  PSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWW 690

Query: 783  TVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLP 842
              +AA +PALL +ILIFMDQQITAVI+NR E++L+KG G+HLDL  VAV++ + S +GLP
Sbjct: 691  WSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLP 750

Query: 843  WFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKF 902
            W+V+ATV+S+ H++SL+ ES   APGE+P FLGIREQR+TGL++FIL G+S+F+  +LKF
Sbjct: 751  WYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKF 810

Query: 903  IPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMS 962
            IPMPVLYG+FLYMG ++L  IQF +R+KL  MPAKHQPD + LRHVPL +VHLFT IQ++
Sbjct: 811  IPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLA 870

Query: 963  CLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEK 1022
            CLGLLWIIK + AAI+FP+M+L LV VRK ++ +F+ +EL WLD+LMPE +++ + +   
Sbjct: 871  CLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQELLWLDELMPE-EERSIPEKGL 929

Query: 1023 EEEQSMLAMEDEGTVQLPLEGHYRDDPSVINIS 1055
            E E S    + E +     E  Y+     INIS
Sbjct: 930  EPEHSFSGSDSEDS-----ELMYQPKAPEINIS 957


>gi|156071474 solute carrier family 4, anion exchanger, member 2
            (erythrocyte membrane protein band 3-like 1) [Homo
            sapiens]
          Length = 1241

 Score =  673 bits (1737), Expect = 0.0
 Identities = 390/1003 (38%), Positives = 568/1003 (56%), Gaps = 71/1003 (7%)

Query: 60   KSHRRHRHRG---HKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHD 116
            KSHR     G   H  RK  +       +GRE     TP  R +           H PH+
Sbjct: 274  KSHRFEDVPGVRRHLVRKNAKGSTQSGREGREPGP--TPRARPR---------APHKPHE 322

Query: 117  LFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILN 176
            +F EL+E+   + ++ +WRETARW+KFEEDVE+  ERW KP+VA+LS  SL ELR  + +
Sbjct: 323  VFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAH 382

Query: 177  GTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIV 236
            G VLLD+   TL  +A  V++Q V S Q+  + R  V  AL+ +H H + +K  +  P  
Sbjct: 383  GAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFS-FPRN 441

Query: 237  RSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENS----------TVDFSK 286
             S   +G      +     +   V+        E + +V RE            T   SK
Sbjct: 442  ISAGSLGSLLGHHHGQGAESDPHVTEPLMGGVPETRLEVERERELPPPAPPAGITRSKSK 501

Query: 287  VDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLG 346
             +L  ++KIP  AEA+ +LVG +EFL R  +AFVRL  AV L  + EVP+P RFLF+LLG
Sbjct: 502  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 561

Query: 347  PLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSI 406
            P      YHEIGRSI+TLM+D+ FH+ AY A +R DL++ I+ FLD   VLPP E     
Sbjct: 562  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 621

Query: 407  RIEPPKNVPSQEKRKIPA----VPNGTAAHGEA----------EPHGGHSGPELQRTGRI 452
             +    +   Q  +K       +P G     ++          E  G      L+RTGR 
Sbjct: 622  LLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRP 681

Query: 453  FGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAI 512
            FGGLI D++R+ P++ SDFRDA   QCLA+ +F+Y A +SP ITFGGLLGE T+  I   
Sbjct: 682  FGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVS 741

Query: 513  ESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTA 572
            E +   ++ G+ + L G QPL ++G +GP+LVFE+  F FC    L YL  R  IG W  
Sbjct: 742  ELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLV 801

Query: 573  TLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELL 632
             L +++VA + S LV +++RFT+E FA LI +IFIYE   KL ++ + +P+         
Sbjct: 802  FLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPL--------- 852

Query: 633  TQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPY- 691
              + C+         G    W  +  +              +SL G+      G   P  
Sbjct: 853  --HGCSASNSSEVDGGENMTWAGARPTLG---------PGNRSLAGQ-----SGQGKPRG 896

Query: 692  VPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAI-G 750
             P+    S++L   T  ++  L++FK SR+FP ++R ++ DF V + IL MVL+DY+I  
Sbjct: 897  QPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIED 956

Query: 751  IPSPKLQVPSVFKPTR-DDRGWFVTPLG---PNPWWTVIAAIIPALLCTILIFMDQQITA 806
              + KL VPS F  T  + RGW + PLG   P P W ++A+++PA+L  ILIFM+ QIT 
Sbjct: 957  TYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITT 1016

Query: 807  VIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSA 866
            +II++KE  L+KG G+HLDLL++  M G+C++ GLPW  AATV S+TH N+L + S+  A
Sbjct: 1017 LIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVA 1076

Query: 867  PGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFF 926
            PG++PK   ++EQRVTGL++ +L+G S+ +  +L+ IP+ VL+G+FLYMG +SL GIQF+
Sbjct: 1077 PGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFY 1136

Query: 927  DRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLAL 986
            +R+ L  MP KH PD  Y++ V   ++HLFT +Q+ CL LLW +  + A++ FP +++  
Sbjct: 1137 ERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILT 1196

Query: 987  VFVRK-LMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSM 1028
            V +R  ++  +FT RE+  LD    E    + E  ++  E  M
Sbjct: 1197 VPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPM 1239


>gi|157671951 solute carrier family 4, anion exchanger, member 3
            isoform 1 [Homo sapiens]
          Length = 1232

 Score =  657 bits (1696), Expect = 0.0
 Identities = 396/984 (40%), Positives = 562/984 (57%), Gaps = 73/984 (7%)

Query: 56   LGGRKSHRRHRHRG-HKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIP 114
            L   KSHR   + G  +H  +   R  G   GR SPS   P  R +     +    +  P
Sbjct: 266  LDDMKSHRLEDNPGVRRHLVKKPSRTQG---GRGSPSGLAPILRRK----KKKKKLDRRP 318

Query: 115  HDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCI 174
            H++F EL+E+     ++  WRETARW+KFEEDVE+  ERW KP+VA+LS  SL ELR  I
Sbjct: 319  HEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTI 378

Query: 175  LNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIP 234
             +G  LLD+   TL  IA +V++  + S Q+  + R  V   L+ +H H N  K +   P
Sbjct: 379  AHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFP 438

Query: 235  IVRSFAD----IGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDLH 290
               S +     +G     P+     A   ++           +D   +   +     D H
Sbjct: 439  RNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGDGH 498

Query: 291  ------FMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFIL 344
                   ++KIP  AEA+ +LVG + FL++   AFVRL+ AVLL+ + EVP+P RFLF++
Sbjct: 499  RGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVM 558

Query: 345  LGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWD- 403
            LGP      YHE+GRSIATLM+D++FH+ AY+A DR DL+S I EFLD   V+PP E + 
Sbjct: 559  LGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEG 618

Query: 404  -------PSIRIEPPKNVPSQEKRKIPAVPNG--TAAHGEA--EPHGGHSGPE---LQRT 449
                    + + E  +    +E+ K+     G  TA   E   E  G  + PE   L RT
Sbjct: 619  RDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDPLLRT 678

Query: 450  GRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRI 509
            G +FGGL+ D++R+ P++ SD RDA   QC+A+ LF+Y A +SP ITFGGLLGE TEG +
Sbjct: 679  GSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLM 738

Query: 510  SAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGL 569
               E +   ++ G+ +SL G QPL ++G +GP+LVFE+  FKFC+   L YL+ R  +GL
Sbjct: 739  GVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGL 798

Query: 570  WTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDL 629
            W     + LVA + S LV YI+ FT+E FA LI +IFIYE   KL+++   +P       
Sbjct: 799  WLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHP------- 851

Query: 630  ELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDH 689
             LL  Y      P     G+L    E N SA       L  +E             G   
Sbjct: 852  -LLPFY-----PPEGALEGSLDAGLEPNGSA-------LPPTE-------------GPPS 885

Query: 690  P-YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYA 748
            P   P+    S+IL   T  ++  L++F+ SR+   K R I+ DF + ++IL MVL+DY+
Sbjct: 886  PRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYS 945

Query: 749  I-GIPSPKLQVPSVFKPTR-DDRGWFVTPLG---PNPWWTVIAAIIPALLCTILIFMDQQ 803
            I    + KL VP+    T  D R WF+ PLG   P P W ++AA +PALL  ILIFM+ Q
Sbjct: 946  ITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQ 1005

Query: 804  ITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESE 863
            ITA+I+++K  +L KG G+HLDLL++  + G+C + GLPW  AATV S+THVN+L +   
Sbjct: 1006 ITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRT 1065

Query: 864  CSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGI 923
              APG++P+   +REQRVTG++I  L+G S+ M ++L+ IP+ VL+G+FLYMG +SL GI
Sbjct: 1066 AIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGI 1125

Query: 924  QFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMV 983
            Q   R+ L  MPAKH P+  Y+  V   ++HLFT IQ+ C+ LLW++K + A++ FP ++
Sbjct: 1126 QLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLL 1185

Query: 984  LALVFVRK-LMDLLFTKRELSWLD 1006
            L  V +R  L+  LF  REL  LD
Sbjct: 1186 LLTVPLRHCLLPRLFQDRELQALD 1209


>gi|157671953 solute carrier family 4, anion exchanger, member 3
            isoform 2 [Homo sapiens]
          Length = 1259

 Score =  657 bits (1696), Expect = 0.0
 Identities = 396/984 (40%), Positives = 562/984 (57%), Gaps = 73/984 (7%)

Query: 56   LGGRKSHRRHRHRG-HKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIP 114
            L   KSHR   + G  +H  +   R  G   GR SPS   P  R +     +    +  P
Sbjct: 293  LDDMKSHRLEDNPGVRRHLVKKPSRTQG---GRGSPSGLAPILRRK----KKKKKLDRRP 345

Query: 115  HDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCI 174
            H++F EL+E+     ++  WRETARW+KFEEDVE+  ERW KP+VA+LS  SL ELR  I
Sbjct: 346  HEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTI 405

Query: 175  LNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIP 234
             +G  LLD+   TL  IA +V++  + S Q+  + R  V   L+ +H H N  K +   P
Sbjct: 406  AHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFP 465

Query: 235  IVRSFAD----IGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKVDLH 290
               S +     +G     P+     A   ++           +D   +   +     D H
Sbjct: 466  RNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGDGH 525

Query: 291  ------FMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFIL 344
                   ++KIP  AEA+ +LVG + FL++   AFVRL+ AVLL+ + EVP+P RFLF++
Sbjct: 526  RGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVM 585

Query: 345  LGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWD- 403
            LGP      YHE+GRSIATLM+D++FH+ AY+A DR DL+S I EFLD   V+PP E + 
Sbjct: 586  LGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEG 645

Query: 404  -------PSIRIEPPKNVPSQEKRKIPAVPNG--TAAHGEA--EPHGGHSGPE---LQRT 449
                    + + E  +    +E+ K+     G  TA   E   E  G  + PE   L RT
Sbjct: 646  RDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDPLLRT 705

Query: 450  GRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRI 509
            G +FGGL+ D++R+ P++ SD RDA   QC+A+ LF+Y A +SP ITFGGLLGE TEG +
Sbjct: 706  GSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLM 765

Query: 510  SAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGL 569
               E +   ++ G+ +SL G QPL ++G +GP+LVFE+  FKFC+   L YL+ R  +GL
Sbjct: 766  GVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGL 825

Query: 570  WTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDL 629
            W     + LVA + S LV YI+ FT+E FA LI +IFIYE   KL+++   +P       
Sbjct: 826  WLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHP------- 878

Query: 630  ELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDH 689
             LL  Y      P     G+L    E N SA       L  +E             G   
Sbjct: 879  -LLPFY-----PPEGALEGSLDAGLEPNGSA-------LPPTE-------------GPPS 912

Query: 690  P-YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYA 748
            P   P+    S+IL   T  ++  L++F+ SR+   K R I+ DF + ++IL MVL+DY+
Sbjct: 913  PRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYS 972

Query: 749  I-GIPSPKLQVPSVFKPTR-DDRGWFVTPLG---PNPWWTVIAAIIPALLCTILIFMDQQ 803
            I    + KL VP+    T  D R WF+ PLG   P P W ++AA +PALL  ILIFM+ Q
Sbjct: 973  ITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQ 1032

Query: 804  ITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESE 863
            ITA+I+++K  +L KG G+HLDLL++  + G+C + GLPW  AATV S+THVN+L +   
Sbjct: 1033 ITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRT 1092

Query: 864  CSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGI 923
              APG++P+   +REQRVTG++I  L+G S+ M ++L+ IP+ VL+G+FLYMG +SL GI
Sbjct: 1093 AIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGI 1152

Query: 924  QFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMV 983
            Q   R+ L  MPAKH P+  Y+  V   ++HLFT IQ+ C+ LLW++K + A++ FP ++
Sbjct: 1153 QLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLL 1212

Query: 984  LALVFVRK-LMDLLFTKRELSWLD 1006
            L  V +R  L+  LF  REL  LD
Sbjct: 1213 LLTVPLRHCLLPRLFQDRELQALD 1236


>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
            sapiens]
          Length = 911

 Score =  563 bits (1451), Expect = e-160
 Identities = 333/933 (35%), Positives = 523/933 (56%), Gaps = 94/933 (10%)

Query: 115  HDLFTELDEICWRE-GEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSC 173
            H ++ EL E+   E  ++  W E ARW++ EE++ + G  W +P+++ L+  SL ELR  
Sbjct: 55   HKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLELRRV 113

Query: 174  ILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRI 233
               GTVLLD+   +L  +A+ +LD+ +   Q+    R  +  AL+ +H H  + +    +
Sbjct: 114  FTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGV 173

Query: 234  -PIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVE---NKNDVSRENSTVDFSKVDL 289
             P V +      +  +P+       Q + PQ +    +    + D   E  +        
Sbjct: 174  KPAVLT------RSGDPS-------QPLLPQHSSLETQLFCEQGDGGTEGHSPS------ 214

Query: 290  HFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLG 349
              ++KIPP +EA+ +LVG  +FL++ V+ FVRL  A  L+ + E+P+P RFLF+LLGP  
Sbjct: 215  GILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEA 273

Query: 350  KGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIR-- 407
                Y ++GR+ ATLM++ VF   AY A+ R +L+  ++ FLD   VLPP +  PS +  
Sbjct: 274  PHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTD-APSEQAL 332

Query: 408  ---IEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKA 464
               +   + +  +  +  PA P+ +   G  + +GG   P LQ+TG++FGGL+ DI+R+ 
Sbjct: 333  LSLVPVQRELLRRRYQSSPAKPDSSFYKG-LDLNGGPDDP-LQQTGQLFGGLVRDIRRRY 390

Query: 465  PYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIA 524
            PY+ SD  DAFS Q LA+ +F+Y A +SP ITFGGLLGE T  ++   E L   ++ GI 
Sbjct: 391  PYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGIL 450

Query: 525  YSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDAS 584
            ++L G QPL ++G +GP+LVFE+  F FC+  GL Y+  R  IG W   L +++VA + S
Sbjct: 451  FALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGS 510

Query: 585  SLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHN 644
             LV +I+R+T+E F+ LI +IFIYE   KL ++ + +P+    +  +L        +P  
Sbjct: 511  FLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLM-----VPKPQG 565

Query: 645  PSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFF 704
            P                                              +P+    S++L  
Sbjct: 566  P----------------------------------------------LPNTALLSLVLMA 579

Query: 705  STVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAI-GIPSPKLQVPSVFK 763
             T   +  L++FK S YFP K+R ++ DF V ++IL MVL+D+ I    + KL VP  FK
Sbjct: 580  GTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFK 639

Query: 764  PTRDD-RGWFVTPLGPN---PWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKG 819
             +    RGW + PLG     P W + A+ +PALL  ILIF++ QIT +I+++ E K+ KG
Sbjct: 640  VSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKG 699

Query: 820  CGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQ 879
             G+HLDLL+V  M GV ++ G+PW  A TV S+TH N+L +  + S PG   +   ++EQ
Sbjct: 700  SGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQ 759

Query: 880  RVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQ 939
            R++GL++ +L+G S+ M  IL  IP+ VL+G+FLYMG +SL GIQ FDRI L + P K+ 
Sbjct: 760  RISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYH 819

Query: 940  PDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRK-LMDLLFT 998
            PD  Y++ V   ++HLFT IQ+ CL +LW++K + A++  P +++  V +R+ L+ L+F 
Sbjct: 820  PDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFR 879

Query: 999  KRELSWLDDLMPESKKKKLEDAEKEEEQSMLAM 1031
              EL  LD    +  K   ++ E  +E   +AM
Sbjct: 880  NVELQCLD---ADDAKATFDEEEGRDEYDEVAM 909


>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
          Length = 891

 Score =  224 bits (572), Expect = 3e-58
 Identities = 185/687 (26%), Positives = 314/687 (45%), Gaps = 56/687 (8%)

Query: 320 VRLSPAVLLQGLAEVPIPTRFLFILLGP--LGKGQQYHEIGRSIATLMTDEVFHDVAYKA 377
           V +S  V  Q   E     RF+ ++L P  +   +   E+ R+ AT+ +D  F     + 
Sbjct: 229 VCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLET 288

Query: 378 KDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEP 437
           +   +    +      +T++  G   P  +     ++P               AH   EP
Sbjct: 289 RTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLP---------------AHRHPEP 333

Query: 438 HGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQ------CLASFLFLYCACM 491
                 P+ +       G+  DI R+ P +  DF D    +       + + LFLY AC+
Sbjct: 334 ------PKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACL 387

Query: 492 SPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFK 551
            P I FG L  E T+G I   +++ G S+ G+ Y+LF GQPL IL +T P+ ++ +++  
Sbjct: 388 LPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRV 447

Query: 552 FCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEAL 611
            C +Y L + S  A  GLW +    +    + S ++    R TEE  A  I I F+ +A+
Sbjct: 448 ICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAV 507

Query: 612 EKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVS 671
           +   ++   Y    + D +  T+ + + V                N S    +  +   S
Sbjct: 508 KGTVKIFWKYYYGHYLD-DYHTKRTSSLVSLSGLGASL-------NASLHTALNASFLAS 559

Query: 672 ECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVS 731
             +     + G+A              S+++   T+ L  TL QFK S Y    VR I+S
Sbjct: 560 PTELPSATHSGQATA----------VLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILS 609

Query: 732 DFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPA 791
           D A+ + +L   LI  + G    ++   S F+    +  + +  +       V  A+   
Sbjct: 610 DCALPIAVLAFSLIS-SHGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLG 665

Query: 792 LLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLS 851
            L ++L F++Q + A ++N  E++L KG  YH DLL++A++    S+ GLPW  AA   S
Sbjct: 666 FLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHS 725

Query: 852 ITHVNSLKLESECSAPGE-QPKFLGIREQRVTGLMIFILMGSSVFMTSI-LKFIPMPVLY 909
             HV +L L  E    G      + ++E R+T L   +L+G S+ +  + L++IP PVLY
Sbjct: 726 PLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLY 785

Query: 910 GVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWI 969
           G+FLY+  +SL G Q   R+ L        P   Y+R VP RK+H FT +Q+  L LL  
Sbjct: 786 GLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCA 845

Query: 970 IKVSR---AAIVFPMMVLALVFVRKLM 993
             +S      ++FP++++A++ +R ++
Sbjct: 846 FGMSSLPYMKMIFPLIMIAMIPIRYIL 872


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 36.6 bits (83), Expect = 0.13
 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)

Query: 62  HRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTEL 121
           H+ HRHRGH       E D  + DG        PS R Q   G E+DD++    D   + 
Sbjct: 211 HQAHRHRGH-----GSEEDEDVSDGHHHHG---PSHRHQ---GHEEDDDDDDDDDDDDDD 259

Query: 122 DEICWREGEDAEWRETARWLKFEEDVEDG 150
           D++       A  R     ++ +EDV DG
Sbjct: 260 DDVSIEYRHQAH-RHQGHGIEEDEDVSDG 287


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 78  ERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRET 137
           E D   EDG E   FD      + + G EDDDE     + F  LDE    E ED E  E 
Sbjct: 177 EEDEDDEDGEEE-EFDEEDDEDEDVEGDEDDDEVSEEEEEFG-LDEEDEDEDEDEEEEEG 234

Query: 138 ARWLKFEEDVEDGGE 152
            +  K + + +D GE
Sbjct: 235 GKGEKRKRETDDEGE 249


>gi|13375827 phafin 2 [Homo sapiens]
          Length = 249

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 13/53 (24%)

Query: 503 EATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKE 555
           EA   RIS +E+ FGA+          GQPLTI    G VL+ E +L K C++
Sbjct: 9   EANTRRISIVENCFGAA----------GQPLTI---PGRVLIGEGVLTKLCRK 48


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
            polymerase [Homo sapiens]
          Length = 1327

 Score = 32.3 bits (72), Expect = 2.5
 Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 35/119 (29%)

Query: 150  GGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHA-------------NTLEEIAD--- 193
            GG++ + PY   L+ H       C+  GT+LLD+               +T+ E  D   
Sbjct: 1088 GGQQGTNPY---LTFH-------CVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGN 1137

Query: 194  ---------MVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIG 243
                     ++  Q+V + +L E   HR  E   + H+H N++ L +  P + +    G
Sbjct: 1138 AGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKG 1196


>gi|58331266 WD repeat domain 59 [Homo sapiens]
          Length = 974

 Score = 32.0 bits (71), Expect = 3.3
 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 15/56 (26%)

Query: 381 NDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAE 436
           ND++ G+DEF++ +++LP          EP K + +++          TA+HGE E
Sbjct: 326 NDILDGVDEFIESISLLP----------EPEKTLHTEDTDH-----QHTASHGEEE 366


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 33/118 (27%), Positives = 44/118 (37%), Gaps = 29/118 (24%)

Query: 60  KSHRRHRHRGHKH-----------RKRDRERDSGLEDGRESPSFD---TPSQRVQFILGT 105
           K +  HRHR H H           R+R R  D   +D R    +D   TPS+   +    
Sbjct: 226 KHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSR 285

Query: 106 EDDDEEHIPHD------LFTELDEICWREGEDAEWRE--TARWLKFEEDVEDGGERWS 155
           E + E H   D      L     +   R G  +  RE   ARW       E+  +RWS
Sbjct: 286 ERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARW-------EEEKDRWS 336


>gi|145279222 WD repeat domain 66 [Homo sapiens]
          Length = 1149

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 991  KLMDLLFTKRELSWLDDLMPE----SKKKKLEDAEKEEEQSMLAMEDEGTVQLPLEGHYR 1046
            +L+  L T+ E   LD + PE    S  ++    E EE+   +  ++ G  +  LE   R
Sbjct: 147  ELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENR 206

Query: 1047 DDPSVINISDEMSKTALWRNLLI---TADNSKDKESSFP 1082
            ++     +SD  SK  + R  L+   T D    K+ S P
Sbjct: 207  EEGQERRVSDIQSKAGISRESLVSSTTEDILFQKDKSTP 245


>gi|239755074 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 160

 Score = 31.2 bits (69), Expect = 5.6
 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)

Query: 402 WDPSIR--IEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSG 443
           WDP+    + PP+    +  R  P V NG +   E + HG H G
Sbjct: 9   WDPAQEGVVSPPRPARLKPDRAGPGVENGPSPGLERQTHGAHGG 52


>gi|239749600 PREDICTED: hypothetical protein XP_002347101 [Homo
           sapiens]
          Length = 160

 Score = 31.2 bits (69), Expect = 5.6
 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)

Query: 402 WDPSIR--IEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSG 443
           WDP+    + PP+    +  R  P V NG +   E + HG H G
Sbjct: 9   WDPAQEGVVSPPRPARLKPDRAGPGVENGPSPGLERQTHGAHGG 52


>gi|239743867 PREDICTED: hypothetical protein XP_002342984 [Homo
           sapiens]
          Length = 160

 Score = 31.2 bits (69), Expect = 5.6
 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)

Query: 402 WDPSIR--IEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSG 443
           WDP+    + PP+    +  R  P V NG +   E + HG H G
Sbjct: 9   WDPAQEGVVSPPRPARLKPDRAGPGVENGPSPGLERQTHGAHGG 52


>gi|59710085 hypothetical protein LOC146562 [Homo sapiens]
          Length = 520

 Score = 31.2 bits (69), Expect = 5.6
 Identities = 14/34 (41%), Positives = 20/34 (58%)

Query: 1000 RELSWLDDLMPESKKKKLEDAEKEEEQSMLAMED 1033
            R++   D L PES      D+E+EEE+ M A+ D
Sbjct: 382  RQMELPDHLSPESSSHSSSDSEEEEEEEMAALGD 415


>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
           isoform 1 [Homo sapiens]
          Length = 721

 Score = 30.8 bits (68), Expect = 7.3
 Identities = 42/202 (20%), Positives = 79/202 (39%), Gaps = 12/202 (5%)

Query: 87  RESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGE--DAEWRETARWLKFE 144
           R S S  TP        G+ D      P    +EL +I   + +  D E R      + +
Sbjct: 310 RNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKELK 369

Query: 145 EDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQ 204
           E + +  E++ K  V+   L +  E  + I     L D+     E++A+   + +  S +
Sbjct: 370 ESLSEVEEKYKKAMVSNAQLDN--EKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKE 427

Query: 205 LNED------VRHRVHEAL--MKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNA 256
           L         ++H++ E    ++Q     ++K   +  I     ++   Q      DK  
Sbjct: 428 LERQKHMCSVLQHKMEELKEGLRQRDELIEEKQRMQQKIDTMTKEVFDLQETLLWKDKKI 487

Query: 257 GQVVSPQSAPACVENKNDVSRE 278
           G +   +   AC+ N+ D+ RE
Sbjct: 488 GALEKQKEYIACLRNERDMLRE 509


>gi|21493045 A-kinase anchor protein 6 [Homo sapiens]
          Length = 2319

 Score = 30.8 bits (68), Expect = 7.3
 Identities = 23/95 (24%), Positives = 48/95 (50%), Gaps = 11/95 (11%)

Query: 196  LDQQVSSGQ--LNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMD 253
            LD   ++G+  +++DVRH + +     HH +NQ   T   P  +SF+++  +    N  D
Sbjct: 1942 LDDSNTAGKEFVSQDVRH-LPKKCPNHHHFENQS--TASTPTEKSFSELALETRFNNRQD 1998

Query: 254  KNA------GQVVSPQSAPACVENKNDVSRENSTV 282
             +A         ++ +SA  C+  + + + EN+++
Sbjct: 1999 SDALKSSDDAPSMAGKSAGCCLALEQNGTEENASI 2033


>gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 30.4 bits (67), Expect = 9.5
 Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 16/94 (17%)

Query: 455 GLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMS-PVITFGGLL----GEATEGRI 509
           GL+LD  R  P   S          LA F      C   P  TF G +    GEAT G++
Sbjct: 203 GLVLDETRDWPESHS----------LALFATSVSPCDGQPATTFLGSVELQEGEATAGQL 252

Query: 510 SAIESLFGASMTGIAYSLFGGQPLTILGSTGPVL 543
             I   FG S   +A+ L    P   LGS GP L
Sbjct: 253 LDILQAFGVSAPKLAW-LSSSLPSERLGSVGPQL 285


>gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 30.4 bits (67), Expect = 9.5
 Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 16/94 (17%)

Query: 455 GLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMS-PVITFGGLL----GEATEGRI 509
           GL+LD  R  P   S          LA F      C   P  TF G +    GEAT G++
Sbjct: 203 GLVLDETRDWPESHS----------LALFATSVSPCDGQPATTFLGSVELQEGEATAGQL 252

Query: 510 SAIESLFGASMTGIAYSLFGGQPLTILGSTGPVL 543
             I   FG S   +A+ L    P   LGS GP L
Sbjct: 253 LDILQAFGVSAPKLAW-LSSSLPSERLGSVGPQL 285


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,814,700
Number of Sequences: 37866
Number of extensions: 2040295
Number of successful extensions: 6749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 6636
Number of HSP's gapped (non-prelim): 64
length of query: 1088
length of database: 18,247,518
effective HSP length: 113
effective length of query: 975
effective length of database: 13,968,660
effective search space: 13619443500
effective search space used: 13619443500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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