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Search of human proteins with 155030232
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
(1130 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 2281 0.0
gi|110349719 titin isoform N2-A [Homo sapiens] 110 8e-24
gi|160707881 formin 2 [Homo sapiens] 107 6e-23
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 98 5e-20
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 95 4e-19
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 92 2e-18
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 91 5e-18
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 90 1e-17
gi|17975763 myelin transcription factor 1 [Homo sapiens] 89 2e-17
gi|47132519 Ras association and pleckstrin homology domains 1 is... 89 2e-17
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 88 4e-17
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 88 4e-17
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens] 88 5e-17
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens] 88 5e-17
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 88 5e-17
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 87 7e-17
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 87 7e-17
gi|163965366 nascent polypeptide-associated complex alpha subuni... 87 7e-17
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 87 1e-16
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 86 2e-16
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 86 2e-16
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 86 2e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 86 2e-16
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 86 2e-16
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 86 2e-16
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 86 2e-16
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 86 3e-16
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 86 3e-16
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 86 3e-16
gi|33356148 formin-like 1 [Homo sapiens] 86 3e-16
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 2281 bits (5910), Expect = 0.0
Identities = 1130/1130 (100%), Positives = 1130/1130 (100%)
Query: 1 MAAAVLSGPSAGSAAGVPGGTGGLSAVSSGPRLRLLLLESVSGLLQPRTGSAVAPVHPPN 60
MAAAVLSGPSAGSAAGVPGGTGGLSAVSSGPRLRLLLLESVSGLLQPRTGSAVAPVHPPN
Sbjct: 1 MAAAVLSGPSAGSAAGVPGGTGGLSAVSSGPRLRLLLLESVSGLLQPRTGSAVAPVHPPN 60
Query: 61 RSAPHLPGLMCLLRLHGSVGGAQNLSALGALVSLSNARLSSIKTRFEGLCLLSLLVGESP 120
RSAPHLPGLMCLLRLHGSVGGAQNLSALGALVSLSNARLSSIKTRFEGLCLLSLLVGESP
Sbjct: 61 RSAPHLPGLMCLLRLHGSVGGAQNLSALGALVSLSNARLSSIKTRFEGLCLLSLLVGESP 120
Query: 121 TELFQQHCVSWLRSIQQVLQTQDPPATMELAVAVLRDLLRYAAQLPALFRDISMNHLPGL 180
TELFQQHCVSWLRSIQQVLQTQDPPATMELAVAVLRDLLRYAAQLPALFRDISMNHLPGL
Sbjct: 121 TELFQQHCVSWLRSIQQVLQTQDPPATMELAVAVLRDLLRYAAQLPALFRDISMNHLPGL 180
Query: 181 LTSLLGLRPECEQSALEGMKACMTYFPRACGSLKGKLASFFLSRVDALSPQLQQLACECY 240
LTSLLGLRPECEQSALEGMKACMTYFPRACGSLKGKLASFFLSRVDALSPQLQQLACECY
Sbjct: 181 LTSLLGLRPECEQSALEGMKACMTYFPRACGSLKGKLASFFLSRVDALSPQLQQLACECY 240
Query: 241 SRLPSLGAGFSQGLKHTESWEQELHSLLASLHTLLGALYEGAETAPVQNEGPGVEMLLSS 300
SRLPSLGAGFSQGLKHTESWEQELHSLLASLHTLLGALYEGAETAPVQNEGPGVEMLLSS
Sbjct: 241 SRLPSLGAGFSQGLKHTESWEQELHSLLASLHTLLGALYEGAETAPVQNEGPGVEMLLSS 300
Query: 301 EDGDAHVLLQLRQRFSGLARCLGLMLSSEFGAPVSVPVQEILDFICRTLSVSSKNISLHG 360
EDGDAHVLLQLRQRFSGLARCLGLMLSSEFGAPVSVPVQEILDFICRTLSVSSKNISLHG
Sbjct: 301 EDGDAHVLLQLRQRFSGLARCLGLMLSSEFGAPVSVPVQEILDFICRTLSVSSKNISLHG 360
Query: 361 DGPLRLLLLPSIHLEALDLLSALILACGSRLLRFGILIGRLLPQVLNSWSIGRDSLSPGQ 420
DGPLRLLLLPSIHLEALDLLSALILACGSRLLRFGILIGRLLPQVLNSWSIGRDSLSPGQ
Sbjct: 361 DGPLRLLLLPSIHLEALDLLSALILACGSRLLRFGILIGRLLPQVLNSWSIGRDSLSPGQ 420
Query: 421 ERPYSTVRTKVYAILELWVQVCGASAGMLQGGASGEALLTHLLSDISPPADALKLRSPRG 480
ERPYSTVRTKVYAILELWVQVCGASAGMLQGGASGEALLTHLLSDISPPADALKLRSPRG
Sbjct: 421 ERPYSTVRTKVYAILELWVQVCGASAGMLQGGASGEALLTHLLSDISPPADALKLRSPRG 480
Query: 481 SPDGSLQTGKPSAPKKLKLDVGEAMAPPSHRKGDSNANSDVCAAALRGLSRTILMCGPLI 540
SPDGSLQTGKPSAPKKLKLDVGEAMAPPSHRKGDSNANSDVCAAALRGLSRTILMCGPLI
Sbjct: 481 SPDGSLQTGKPSAPKKLKLDVGEAMAPPSHRKGDSNANSDVCAAALRGLSRTILMCGPLI 540
Query: 541 KEETHRRLHDLVLPLVMGVQQGEVLGSSPYTSSRCRRELYCLLLALLLAPSPRCPPPLAC 600
KEETHRRLHDLVLPLVMGVQQGEVLGSSPYTSSRCRRELYCLLLALLLAPSPRCPPPLAC
Sbjct: 541 KEETHRRLHDLVLPLVMGVQQGEVLGSSPYTSSRCRRELYCLLLALLLAPSPRCPPPLAC 600
Query: 601 ALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPF 660
ALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPF
Sbjct: 601 ALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPF 660
Query: 661 RAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVP 720
RAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVP
Sbjct: 661 RAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVP 720
Query: 721 PRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISL 780
PRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISL
Sbjct: 721 PRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISL 780
Query: 781 ESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLP 840
ESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLP
Sbjct: 781 ESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLP 840
Query: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE 900
PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE
Sbjct: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE 900
Query: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV 960
EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV
Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV 960
Query: 961 EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA 1020
EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA
Sbjct: 961 EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA 1020
Query: 1021 DTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
DTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP
Sbjct: 1021 DTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
Query: 1081 ETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
ETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS
Sbjct: 1081 ETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 110 bits (275), Expect = 8e-24
Identities = 132/459 (28%), Positives = 190/459 (41%), Gaps = 67/459 (14%)
Query: 725 PGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDS 784
P PE + + + ++ PP P+ +V + +EE VE++ E +
Sbjct: 10186 PVPEIKKKVTEKKVVIPKKEEAPPAKVPEVP--KKVEEKRIILPKEEEVLPVEVTEEPEE 10243
Query: 785 DD-----------SVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVP-AKEEPEEL 832
+ S+ V E PP P A P P +PP +K+ PEE
Sbjct: 10244 EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEE- 10302
Query: 833 PAAPGPLPPPPPPPPPVPG-PVTLPPPQ-LVP--EGTPGGGGPPALEEDLTVININSSDE 888
P P+ PP VP P +P + LVP E P G LEE ++V
Sbjct: 10303 -KVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVV 10361
Query: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE-EEEEEF---EEEFEEEEGELEE 944
+E E E E E EE EEE+F E EEYFEE E E EEF E+ EEE +E+
Sbjct: 10362 KERLELEVVEAEVEEIPEEEEFHE----VEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEK 10417
Query: 945 EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPG 1004
+ E EE+E E + G E+ E PP P + P + PP PE +
Sbjct: 10418 VHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKK-- 10475
Query: 1005 LLLEVEEPGTEEERGADTAPTLAPEALPSQGEVERE------GESPAAGPP-----PQEL 1053
+++E + EE R PT PE LP + V + + P A PP P+E+
Sbjct: 10476 IVVEEKVRVPEEPR---VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEV 10532
Query: 1054 VEE---------EPSAPPTLLEEETEDG--SDKV---------QPPPETP-AEEEMETET 1092
V E +P PPT + E + KV PPPE P A +E+ E
Sbjct: 10533 VPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEK 10592
Query: 1093 EAEALQEKEQDDTAAMLADF-IDCPPDDEKP-PPPTEPD 1129
+ A K+ + T + + + P+ + P PPP +P+
Sbjct: 10593 KVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631
Score = 97.4 bits (241), Expect = 7e-20
Identities = 144/549 (26%), Positives = 194/549 (35%), Gaps = 99/549 (18%)
Query: 633 PRVPPLQPMGPTCPTPAPVPP----PEAPSPFRAPPFHPPGPMPSVGSMPSA----GPMP 684
P PP +P P PT P P PE P PP P P P V P +P
Sbjct: 10539 PVPPPKKPEVP--PTKVPEVPKAAVPEKKVPEAIPP-KPESPPPEVPEAPKEVVPEKKVP 10595
Query: 685 SAGPM-PSAGPV--PSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILA 741
+A P P PV P A P + + P VPP +P + P
Sbjct: 10596 AAPPKKPEVTPVKVPEA-PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAI 10654
Query: 742 PSGTPPPTIPPDETFG-----GRVPRPAFVHYDKEEASDVEISL-------ESDSDDSVV 789
P P P PP E F PA V + E A+ ++++ E + V
Sbjct: 10655 P---PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVA 10711
Query: 790 IVPEGLPPLPPPPPSGATPP-------PIAPTGPPTASPPVPAKEEPEELPAAPGPLPPP 842
PE P P P P P P PP P VP + PE+ A P P
Sbjct: 10712 KKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP 10771
Query: 843 PPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEE 902
P P VP L VP PP E EE EE EEE
Sbjct: 10772 PAKVPEVPKKPVLEEKPAVPVPERAESPPP---------------EVYEEPEEIAPEEEI 10816
Query: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
EEE+ EE+E E EE ++ E++ + ++ E +E E + +E
Sbjct: 10817 APEEEKPVPVAEEEEPEV--PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEK 10874
Query: 963 LEFGTAGGEVEEGAPPPPTLPP------------ALPPPESPPKVQPEPEPEPGLLLEVE 1010
+++ PPPP PP A+P + P K Q PE L ++
Sbjct: 10875 -------PKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQ---VPEKVELTPLK 10924
Query: 1011 EPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETE 1070
PG E++ L PE P E + E + EEEP P LE+ +
Sbjct: 10925 VPGGEKK-----VRKLLPERKP-----EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKK 10974
Query: 1071 DGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKP-------- 1122
+PPP P EE+E T + ++ + + I P + KP
Sbjct: 10975 PAVP--EPPPPKPV-EEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKT 11031
Query: 1123 --PPPTEPD 1129
PPP EP+
Sbjct: 11032 IKPPPVEPE 11040
Score = 93.6 bits (231), Expect = 1e-18
Identities = 138/519 (26%), Positives = 190/519 (36%), Gaps = 111/519 (21%)
Query: 636 PPLQPMGPTCPTP---APVPPPEAPSPFRAP--PFHPPGPMPSVGSMPSAGPMPSAGPMP 690
PP P P P P APVP P+ P AP P P P+P P+P P
Sbjct: 9285 PPKVPELPEKPAPEEVAPVPIPKKVEP-PAPKVPEVPKKPVPE-----EKKPVPVPKKEP 9338
Query: 691 SAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP-SGTPPPT 749
+A P P P + + V PP +P + + I+ +PPP
Sbjct: 9339 AAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPA 9398
Query: 750 IPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPP 809
+P +P+ VPE P+P PP
Sbjct: 9399 VP-------EIPKKK--------------------------VPEERKPVPRKEEEVPPPP 9425
Query: 810 PIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPP-PPVPGPVTLPPPQLVPEGTPGG 868
+ P +P K PEE A P P+ PPP V + + V E
Sbjct: 9426 KV---------PALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSF 9476
Query: 869 GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928
P +E + S++EE EEEE EEE EEEE + EY EE EE
Sbjct: 9477 AVPQRVEVTRHEV---SAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEE 9533
Query: 929 EEFEEEFEEEEGELEEEEEEEDEEEEE----------ELEEVEDLEFGTAGGEV--EEGA 976
EE+ +E E E E +E+ ++EE + A ++ E+
Sbjct: 9534 YVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKV 9593
Query: 977 P---------PPPTLP--PALPPPES--PPKVQPEPEPEPGLLLEVEEPGTEEER--GAD 1021
P PPP +P P P PE PPKV EP P + E T+EE+ A
Sbjct: 9594 PAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAV 9653
Query: 1022 TAPTLAPEALPSQGEVEREGESPAAGPPPQELV------EEEPSAPPT------LLEEET 1069
T P+A R E P P ++++ EEEP A T + EE+
Sbjct: 9654 TKKEAPPKA--------RVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKV 9705
Query: 1070 EDGSDKVQPPP--ETPAEEEME----TETEAEALQEKEQ 1102
+ K +P P E EE E E EA ++Q +E+
Sbjct: 9706 SIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEE 9744
Score = 93.2 bits (230), Expect = 1e-18
Identities = 144/562 (25%), Positives = 200/562 (35%), Gaps = 123/562 (21%)
Query: 651 VPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVP---SARPGPPTTAN 707
+ PE P P + P P +P+ P A + A P PVP +P PP
Sbjct: 9786 ITEPEKPIPVKPVPEEP---VPTKPKAPPAKVLKKAVPEEKV-PVPIPKKLKPPPPKVPE 9841
Query: 708 H--------LGLSVPGL----VSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDET 755
+ +S+ V+ P +P + P+ PP +P
Sbjct: 9842 EPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVP---- 9897
Query: 756 FGGRVPR---PAFVHYDKEEASDVEISLESDSDDSV-----------------VIVPEGL 795
VP+ P V +++E + VE L + ++ + V VPE +
Sbjct: 9898 ---EVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPE-V 9953
Query: 796 PPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPG---- 851
P P P P P PP P VP K E + P PPP P VP
Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013
Query: 852 ----PVTLP-----PPQLVPE--------------GTPGGGGPPA---------LEEDLT 879
PV +P PP VPE PPA + E+
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKK 10073
Query: 880 VININSSDEEEEEEEEEEEEEEE-----EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
+ E + ++ E +EEE FEEE EEE EEEE E EE
Sbjct: 10074 PTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEV 10133
Query: 935 FEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPK 994
EEE L EEEE EEEE EE E+ E EE P L PE PK
Sbjct: 10134 LPEEEEVLPEEEEIPPEEEEVPPEE----EYVP---EEEEFVPEEEVL------PEVKPK 10180
Query: 995 VQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELV 1054
V P P P P + +V E + + P PE +P + E +R L
Sbjct: 10181 V-PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPE-VPKKVEEKR-----------IILP 10227
Query: 1055 EEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME--TETEAEALQEKEQDDTAAMLADF 1112
+EE P + EE E+ + + P E P+ EE+E + +K + +
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKK 10287
Query: 1113 IDCPP-------DDEKPPPPTE 1127
++ PP +EK P P +
Sbjct: 10288 VEAPPAKVSKKIPEEKVPVPVQ 10309
Score = 92.0 bits (227), Expect = 3e-18
Identities = 126/515 (24%), Positives = 187/515 (36%), Gaps = 82/515 (15%)
Query: 588 LAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPT 647
+ P P PPP + F E+ EV AL A P P T P
Sbjct: 10654 IPPKPESPPP-----EVF-----EEPEEV------ALEEPPAEVVEEPEPAAPPQVTVPP 10697
Query: 648 PAPVPPPEAPSPFRAPPFHPPGPMPSVGS-MPSAGPMPSAGPMPSAGPVPSARPGPPTTA 706
PVP +AP+ P PP +P V + +P P P P
Sbjct: 10698 KKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV 10757
Query: 707 NHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFV 766
++VP VPP +P + P+L P +P E P P
Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVP-------KKPVLEEK----PAVPVPER--AESPPPEVY 10804
Query: 767 HYDKEEASDVEISLESDSDDSVVIV--PEGLPPLPPPPPSGATPPPIAPTGPPTASPPVP 824
+E A + EI+ E + V PE PP P P P P +PP P
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPP-P 10863
Query: 825 AKEEPEELPAAPG--PLPPPPPPPPPVPG------PVTLPPPQLVPEGTPGGGGPPALEE 876
+ EPE++ P P PPPPPP PP + P + VPE P + E
Sbjct: 10864 KEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPE-------KPQVPE 10916
Query: 877 --DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
+LT + + +++ + E + E +EE + + +EEE
Sbjct: 10917 KVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEE--------------- 10961
Query: 935 FEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPP---PTLPPALPPPES 991
+ E + E+ ++ E + VE++E T E P P P + PA+P P
Sbjct: 10962 -PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR-ERKIPEPTKVPEIKPAIPLPA- 11018
Query: 992 PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQ 1051
PEP+P+P ++ +P E + P AP +P G+ P+
Sbjct: 11019 -----PEPKPKPEAEVKTIKPPPVE---PEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK 11070
Query: 1052 ELVEEEPSAPPTLLEEE---TEDGSDKVQPPPETP 1083
++ P P+ +E E GS +PP E P
Sbjct: 11071 GPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAP 11105
Score = 82.8 bits (203), Expect = 2e-15
Identities = 142/543 (26%), Positives = 186/543 (34%), Gaps = 167/543 (30%)
Query: 630 LTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGP- 688
+T V P+ P+ PVP + P P PP +P V P +P P
Sbjct: 9937 ITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEE-KVPVLIPK 9995
Query: 689 --MPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPS--G 744
P VP P P + + VP V PP +P + P+ AP
Sbjct: 9996 KEKPPPAKVPEV-PKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVE 10054
Query: 745 TPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPS 804
PP +P VP+ ++PE P P P
Sbjct: 10055 APPAKVP-------EVPKK--------------------------LIPEEKKPTPVPKKV 10081
Query: 805 GATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG 864
A P P VP K E PVP PV LP + V
Sbjct: 10082 EAPP------------PKVPKKRE-------------------PVPVPVALPQEEEV--- 10107
Query: 865 TPGGGGPPALEEDLTVININSSDEEE---EEEEEEEEEEEEEEEEEEDFEEEEE--DEEE 919
EE++ +EEE EEEE EEEE EEEE EEEE EEE
Sbjct: 10108 --------LFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE 10159
Query: 920 YFEEEEE---EEE-----------------------------------------EFEEEF 935
Y EEEE EEE E ++
Sbjct: 10160 YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKV 10219
Query: 936 EEEEGELEEEE-----EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPP--PPTLPPALP- 987
EE+ L +EE E +E EEE + E E E + EVEE APP P + A+P
Sbjct: 10220 EEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPE 10279
Query: 988 -PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046
P P KV+ P + E + P P EA P+ + E P
Sbjct: 10280 APTPVPKKVEAPPAKVSKKIPEEKVP----------VPVQKKEAPPA-----KVPEVPKK 10324
Query: 1047 GPPPQELVEEEPSAPP----TLLEEETEDGSDKVQPPPETPAEEEME---TETEAEALQE 1099
P + LV ++ + PP T+LEE+ V E +E +E E E E + E
Sbjct: 10325 VPEKKVLVPKKEAVPPAKGRTVLEEKV-----SVAFRQEVVVKERLELEVVEAEVEEIPE 10379
Query: 1100 KEQ 1102
+E+
Sbjct: 10380 EEE 10382
Score = 80.5 bits (197), Expect = 8e-15
Identities = 102/402 (25%), Positives = 155/402 (38%), Gaps = 78/402 (19%)
Query: 799 PPPPPSGATPPPIAPTG--PPTASPPVPAKEEPEELPAAPGPLPPP-------------- 842
PP P P P P PP PPV A P LP PPP
Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDA 8993
Query: 843 ------PPPPPPVPGPVTLPPPQ--LVPEGTPGGGGPPALEEDLTVININSSDEEEEEEE 894
P P V PPP L+P P + E++ ++ I E ++E+E
Sbjct: 8994 KKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKE 9053
Query: 895 EEEEEEEEEEEEE----EDFEEEEED----------EEEYFEEEEEE------------E 928
E+++ +E+ E FEE ++ E+ Y+EE +E+
Sbjct: 9054 AVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVH 9113
Query: 929 EEFEEEFEEEEGELEEEE--EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPAL 986
EE+EE+FEE + E EE +E +EE EE +E E ++ E P +P
Sbjct: 9114 EEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKK 9173
Query: 987 PPPESPPKVQPEP--EPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREG--- 1041
PP PPKV +P E +EE + + + + + P+ PS+ V+ E
Sbjct: 9174 APP--PPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQK-PSRTPVQEEVIEV 9230
Query: 1042 ESPAAGPPPQELVEEEP------------SAPPTLLEEETEDG-----SDKVQPPPETP- 1083
+ PA + EE+ + P E TE+ S +V+PPP+ P
Sbjct: 9231 KVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPE 9290
Query: 1084 AEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPP 1125
E+ E A K+ + A + + P +EK P P
Sbjct: 9291 LPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVP 9332
Score = 74.3 bits (181), Expect = 6e-13
Identities = 135/580 (23%), Positives = 196/580 (33%), Gaps = 130/580 (22%)
Query: 621 SEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSA 680
+E +T PP P P VP P P + PP P V ++P
Sbjct: 9381 TEEKITIVTQREESPPPAVPEIPK----KKVPEERKPVPRKEEEVPPP---PKVPALPKK 9433
Query: 681 GPMPSAGPMPSAGPVPSARPGPPTTAN----------------HLGLSVPGLVSVPPRLL 724
P+P A PVP A+ PP A L +VP V V +
Sbjct: 9434 -PVPEE---KVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEV 9489
Query: 725 PGPEN--------------HRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDK 770
E +R E+ A P+E V + +
Sbjct: 9490 SAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYV---VEEKLHIISKR 9546
Query: 771 EEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEE-- 828
EA E++ + +V+ P+ + PPP+ P PVP KE+
Sbjct: 9547 VEAEPAEVTERQEK--KIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVP 9604
Query: 829 PEELPAAPG-PLPPPPPPPP------PVPGPVT--------------------LPPPQLV 861
P ++P P P+P PP P+P VT PP V
Sbjct: 9605 PPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARV 9664
Query: 862 PEGTPGG--------------GGPPA---------LEEDLTVININSSDEEEEEE----E 894
PE PPA ++E+ I + + +E E
Sbjct: 9665 PEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIME 9724
Query: 895 EEE-----EEEEEEEEEEEDFEEEEE-DEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
E+E EEE + EE++EE EE D +E+ E E EE + EE+EE E E EE EE
Sbjct: 9725 EKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEE 9784
Query: 949 EDEEEEEEL------EEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPE 1002
E E+ + EE + +V + A P +P +P PP + EP+
Sbjct: 9785 YITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPK 9844
Query: 1003 PGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPP 1062
++ T+ E+ T P P + E + P P V E P
Sbjct: 9845 KVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVP---- 9900
Query: 1063 TLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQ 1102
K P E EEE+ T E ++E+E+
Sbjct: 9901 ------------KELEPEEVAFEEEVVTHVEEYLVEEEEE 9928
Score = 35.0 bits (79), Expect = 0.40
Identities = 38/135 (28%), Positives = 55/135 (40%), Gaps = 14/135 (10%)
Query: 631 THPRVPPL----QPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSA 686
T PR+PP P P+ A + ++PSP R H P P+ V + P+ P+ S
Sbjct: 253 TPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR----HSPSPVRHVRA-PTPSPVRSV 307
Query: 687 GPMP--SAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSG 744
P S P+ S R P +V VPP E + A S+E + +
Sbjct: 308 SPAARISTSPIRSVR-SPLLMRKTQASTVATGPEVPPPW--KQEGYVASSSEAEMRETTL 364
Query: 745 TPPPTIPPDETFGGR 759
T I +E + GR
Sbjct: 365 TTSTQIRTEERWEGR 379
Score = 33.9 bits (76), Expect = 0.90
Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 6/101 (5%)
Query: 759 RVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSG--ATPPPIAPTGP 816
R+ + H+D + VE+ ++ + + P PP PP P TPP IA
Sbjct: 220 RIEKKIEAHFDARSIATVEMVIDGAAGQQL---PHKTPPRIPPKPKSRSPTPPSIAAKAQ 276
Query: 817 -PTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP 856
P P + P + P P P P T P
Sbjct: 277 LARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSP 317
Score = 32.0 bits (71), Expect = 3.4
Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 24/112 (21%)
Query: 894 EEEEEEEEEEEEEEEDFEEEEEDEEEYFE-------EEEEEEEEFEEEFEEEEGELEEEE 946
E E+ EE EE + + EE Y+E + +++E +EE + + EL
Sbjct: 1983 ERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWT 2042
Query: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPP---ALPPPESPPKV 995
+E EEE++ L EEG PT P L P PK+
Sbjct: 2043 KELTEEEKKAL--------------AEEGKITIPTFKPDKIELSPSMEAPKI 2080
Score = 30.4 bits (67), Expect = 9.9
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 895 EEEEEEEEEEEEEEDFEEEEEDEEEY----FEEEEEEEEEFEEEFEEEEGELEEEEEEED 950
EEEE + E + D +E E+ Y F + E ++ EEE LE EE E
Sbjct: 8573 EEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERS 8632
Query: 951 EEEEEELEEV 960
E +E+E EE+
Sbjct: 8633 ERDEKEFEEL 8642
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 107 bits (267), Expect = 6e-23
Identities = 91/278 (32%), Positives = 109/278 (39%), Gaps = 71/278 (25%)
Query: 635 VPPLQPM-GPTCPTPAPVP----PPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAG-- 687
+PP P+ G P P P+P PP P P P PP P+P G +P P+P AG
Sbjct: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAG-IPPPPPLPGAGIP 1031
Query: 688 ---PMPSAG-----PVPSARPGPPTTANHLGL----SVPGLVSVPPRLLPGPENHRAGSN 735
P+P AG P+P A PP G+ +PG PP LPG AG
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-----AGIP 1086
Query: 736 EDPILAPSGTPPP-------TIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSV 788
P L +G PPP PP G +P P
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP------------------------ 1122
Query: 789 VIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPP----- 843
+ G+PP PP P +G PPP P PP+P P P +PPPP
Sbjct: 1123 PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1182
Query: 844 --PPPPPVPGPVTLPPPQL------VPEGTPGGGGPPA 873
PPPPP+PG PPP L P PG G PPA
Sbjct: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPA 1220
Score = 105 bits (263), Expect = 2e-22
Identities = 87/264 (32%), Positives = 108/264 (40%), Gaps = 63/264 (23%)
Query: 635 VPPLQPM-GPTCPTPAPVP----PPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAG-- 687
+PP P+ G P P P+P PP P P P PP P+P G +P P+P AG
Sbjct: 1008 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAG-IPPPPPLPGAGIP 1064
Query: 688 ---PMPSAG-----PVPSARPGPPTTANHLGL----SVPGLVSVPPRLLPGPENHRAGSN 735
P+P AG P+P A PP G+ +PG+ PP LPG AG
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG-----AGIP 1119
Query: 736 EDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGL 795
P L +G PPP P G +P P + G+
Sbjct: 1120 PPPPLPGAGIPPPPPLP----GAGIPPPP------------------------PLPRVGI 1151
Query: 796 PPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPP-------PPPPP 848
PP PP P +G PPP P PP+P P P +PPPP PPPPP
Sbjct: 1152 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
Query: 849 VPGPVTLPPPQLVPEGTPGGGGPP 872
+PG + +PP P PG G PP
Sbjct: 1212 LPG-MGIPPAPAPPLPPPGTGIPP 1234
Score = 99.4 bits (246), Expect = 2e-20
Identities = 84/257 (32%), Positives = 103/257 (40%), Gaps = 64/257 (24%)
Query: 635 VPPLQPM-GPTCPTPAPVP----PPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPM 689
+PP P+ G P P P+P PP P P P PP P+P G +P P+P AG +
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAG-IPPPPPLPGAG-I 1096
Query: 690 PSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPT 749
P P+P PP +PG PP LPG AG P L +G PPP
Sbjct: 1097 PPPPPLPGVGIPPPP-------PLPGAGIPPPPPLPG-----AGIPPPPPLPGAGIPPP- 1143
Query: 750 IPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPP 809
PP G P P + G+PP PP P +G PP
Sbjct: 1144 -PPLPRVGIPPPPP--------------------------LPGAGIPPPPPLPGAGIPPP 1176
Query: 810 PIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPP---------PPPPVPGPVT-LPPPQ 859
P P PP+P P P +PPPPP P PP+P P T +PPP
Sbjct: 1177 PPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236
Query: 860 LVPEGTPGGGGPPALEE 876
L+P GPP L +
Sbjct: 1237 LLPV-----SGPPLLPQ 1248
Score = 95.5 bits (236), Expect = 3e-19
Identities = 88/286 (30%), Positives = 105/286 (36%), Gaps = 86/286 (30%)
Query: 595 PPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMG-PTCPTPAPVPP 653
PPPL C + S+ + P PPL M PT P+ A P
Sbjct: 858 PPPLPCTESSSSMPG------------------LGMVPPPPPPLPGMTVPTLPSTAIPQP 899
Query: 654 PEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSV 713
P PP PP P+P G +P P+P AG +P P+P A PP +
Sbjct: 900 PPLQGTEMLPP--PPPPLPGAG-IPPPPPLPGAGILPLP-PLPGAGIPPPPP-------L 948
Query: 714 PGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEA 773
PG PP LPG AG P L +G PPP PP
Sbjct: 949 PGAAIPPPPPLPG-----AGIPLPPPLPGAGIPPP--PP--------------------- 980
Query: 774 SDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELP 833
+ G+PP PP P +G PPP P PP+P P P
Sbjct: 981 ----------------LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
Query: 834 AAPGPLPPPPP-P------PPPVPGPVTLPPPQLVPEGTPGGGGPP 872
+PPPPP P PPP+PG PPP L PG G PP
Sbjct: 1025 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-----PGAGIPP 1065
Score = 94.7 bits (234), Expect = 4e-19
Identities = 94/315 (29%), Positives = 117/315 (37%), Gaps = 59/315 (18%)
Query: 635 VPPLQPM-GPTCPTPAPVP----PPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPM 689
+PP P+ G P P P+P PP P P P PP P+P VG +P P+P AG +
Sbjct: 1063 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGVG-IPPPPPLPGAG-I 1118
Query: 690 PSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPT 749
P P+P A PP +PG PP LP R G P L +G PPP
Sbjct: 1119 PPPPPLPGAGIPPPP-------PLPGAGIPPPPPLP-----RVGIPPPPPLPGAGIPPPP 1166
Query: 750 IPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPP 809
P G +P P + G+PP PP P G PP
Sbjct: 1167 PLP----GAGIPPPP------------------------PLPGVGIPPPPPLPGVGIPPP 1198
Query: 810 PIAPTGPPTASPPVPAKEEPEELPAAPGPLPP-----PPPPPPPVPGPVTLPP--PQLVP 862
P P PP+P P PA PLPP PPPP PV GP LP +P
Sbjct: 1199 PPLPGAGIPPPPPLPGMGIP---PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP 1255
Query: 863 EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE 922
G PP L L + +N ++ E + + +
Sbjct: 1256 TPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIW 1315
Query: 923 EEEEEEEEFEEEFEE 937
E+ EE EFEE
Sbjct: 1316 EKIEEPSIDCHEFEE 1330
Score = 57.0 bits (136), Expect = 1e-07
Identities = 51/135 (37%), Positives = 60/135 (44%), Gaps = 23/135 (17%)
Query: 633 PRVPPLQPMGPTCPTPAPVP----PPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAG- 687
P PPL +G P P P+P PP P P P PP P+P VG +P P+P G
Sbjct: 1141 PPPPPLPRVG--IPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGVG-IPPPPPLPGVGI 1195
Query: 688 ----PMPSAG-PVPSARPG---PPTTANHLGLSVPGLVSVPPRLLP---GPENHRAGSNE 736
P+P AG P P PG PP A L PG PP LLP P + GS+
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTGIPPPPLLPVSGPPLLPQVGSST 1253
Query: 737 DPILAPSGTPPPTIP 751
P G PP +P
Sbjct: 1254 LPTPQVCGFLPPPLP 1268
Score = 46.2 bits (108), Expect = 2e-04
Identities = 44/156 (28%), Positives = 61/156 (39%), Gaps = 24/156 (15%)
Query: 799 PPPPPSGATPPP----------IAPTGPPTASPPVPAKEE--------PEELPAAPG-PL 839
P PP+ +P P + P+G +P P E+ PE L A P P
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291
Query: 840 PPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALE----EDLTVININSS-DEEEEEEE 894
PP P PV +LP Q + +P P E E+ + + D +EE EE
Sbjct: 292 QPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE 351
Query: 895 EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930
+ E+ EE E ED + EE EEE +
Sbjct: 352 DAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQ 387
Score = 41.6 bits (96), Expect = 0.004
Identities = 40/112 (35%), Positives = 42/112 (37%), Gaps = 18/112 (16%)
Query: 975 GAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
G PPPP LP A PPP P P P P PG V P GA P P LP
Sbjct: 1073 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG----VGIPPPPPLPGAGIPP---PPPLP 1125
Query: 1033 SQGEVEREGESPAAG-PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
G + P AG PPP L PP L + PPP P
Sbjct: 1126 GAG-IPPPPPLPGAGIPPPPPLPRVGIPPPPPL-------PGAGIPPPPPLP 1169
Score = 40.4 bits (93), Expect = 0.010
Identities = 39/112 (34%), Positives = 42/112 (37%), Gaps = 18/112 (16%)
Query: 975 GAPPPPTLPPAL--PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
G PPPP LP A PPP P P P P PG + P GA P P LP
Sbjct: 941 GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI----PPPPPLPGAGIPP---PPPLP 993
Query: 1033 SQGEVEREGESPAAG-PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
G + P AG PPP L PP L + PPP P
Sbjct: 994 GAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPL-------PGAGIPPPPPLP 1037
Score = 40.4 bits (93), Expect = 0.010
Identities = 39/112 (34%), Positives = 42/112 (37%), Gaps = 18/112 (16%)
Query: 975 GAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
G PPPP LP A PPP P P P P PG + P GA P P LP
Sbjct: 1007 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI----PPPPPLPGAGIPP---PPPLP 1059
Query: 1033 SQGEVEREGESPAAG-PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
G + P AG PPP L PP L + PPP P
Sbjct: 1060 GAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPL-------PGAGIPPPPPLP 1103
Score = 40.0 bits (92), Expect = 0.013
Identities = 39/112 (34%), Positives = 42/112 (37%), Gaps = 18/112 (16%)
Query: 975 GAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
G PPPP LP A PPP P P P P PG + P GA P P LP
Sbjct: 1018 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI----PPPPPLPGAGIPP---PPPLP 1070
Query: 1033 SQGEVEREGESPAAG-PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
G + P AG PPP L PP L + PPP P
Sbjct: 1071 GAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPL-------PGVGIPPPPPLP 1114
Score = 38.5 bits (88), Expect = 0.036
Identities = 37/112 (33%), Positives = 40/112 (35%), Gaps = 18/112 (16%)
Query: 975 GAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
G PPPP LP A LP P P P P P PG + P A P LP
Sbjct: 919 GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP-------LPGAGIPLPPPLP 971
Query: 1033 SQGEVEREGESPAAG-PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
G + P AG PPP L PP L + PPP P
Sbjct: 972 GAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPL-------PGAGIPPPPPLP 1015
Score = 38.1 bits (87), Expect = 0.048
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 975 GAPPPPTLP-PALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT-----LAP 1028
G PPPP LP +PP +PP P P LL V P + G+ T PT P
Sbjct: 1205 GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLP 1264
Query: 1029 EALPS 1033
LPS
Sbjct: 1265 PPLPS 1269
Score = 37.7 bits (86), Expect = 0.062
Identities = 32/120 (26%), Positives = 41/120 (34%), Gaps = 9/120 (7%)
Query: 637 PLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVP 696
P +P P P+P +P EAPS A P P + P AGP A P G
Sbjct: 287 PREPQQP--PSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGD 344
Query: 697 SARPGPPTTANHLGLSVPGL-------VSVPPRLLPGPENHRAGSNEDPILAPSGTPPPT 749
+ G PG P RL PE G + + G+P P+
Sbjct: 345 TDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPS 404
Score = 37.7 bits (86), Expect = 0.062
Identities = 27/77 (35%), Positives = 31/77 (40%), Gaps = 15/77 (19%)
Query: 975 GAPPPPTLPPA-LPPPESPPKVQ-PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
G PPPP LP A +PPP P V P P P PG+ G P L +P
Sbjct: 1161 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGV-------------GIPPPPPLPGAGIP 1207
Query: 1033 SQGEVEREGESPAAGPP 1049
+ G PA PP
Sbjct: 1208 PPPPLPGMGIPPAPAPP 1224
Score = 37.0 bits (84), Expect = 0.11
Identities = 37/110 (33%), Positives = 40/110 (36%), Gaps = 14/110 (12%)
Query: 975 GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034
G PPPP LP A PP PP + P P L V P GA P P LP
Sbjct: 1117 GIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPP---PPPLPGA 1171
Query: 1035 GEVEREGESPAAG-PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
G + P G PPP L PP L + PPP P
Sbjct: 1172 G-IPPPPPLPGVGIPPPPPLPGVGIPPPPPL-------PGAGIPPPPPLP 1213
Score = 36.6 bits (83), Expect = 0.14
Identities = 38/142 (26%), Positives = 50/142 (35%), Gaps = 25/142 (17%)
Query: 952 EEEEELEEVEDLEFGTAGGEVEEGAPPPP---------TLPPALPPPESPPKVQPEPEPE 1002
+ E+ L + DL A E PP P +LP A P + P P PE
Sbjct: 268 DTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPE 327
Query: 1003 PGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPP 1062
G PG E A AP +GE + ++P P + E AP
Sbjct: 328 AG-------PGEE----AAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQ 376
Query: 1063 TLLEEETEDGSDKVQPPPETPA 1084
L EE E+ P+ PA
Sbjct: 377 RLGEEPEEEAQG-----PDAPA 393
Score = 35.4 bits (80), Expect = 0.31
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 11/104 (10%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PPPP P + P P P+P P G E+ P GA P P LP G
Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQG--TEMLPPPPPPLPGAGIPP---PPPLPGAGI 931
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
+ A PPP L PP L G+ PPP
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPL------PGAGIPLPPP 969
Score = 33.1 bits (74), Expect = 1.5
Identities = 37/116 (31%), Positives = 41/116 (35%), Gaps = 23/116 (19%)
Query: 974 EGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPS 1033
E PPP PP LP PP P P P G+L PG G P L A+P
Sbjct: 906 EMLPPP---PPPLPGAGIPP---PPPLPGAGILPLPPLPGA----GIPPPPPLPGAAIPP 955
Query: 1034 QGEVEREG-----ESPAAG-PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
+ G P AG PPP L PP L + PPP P
Sbjct: 956 PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL-------PGAGIPPPPPLP 1004
Score = 32.0 bits (71), Expect = 3.4
Identities = 43/211 (20%), Positives = 81/211 (38%), Gaps = 25/211 (11%)
Query: 916 DEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975
D + Y E+E+ + ++ L+++++++ + + ++ ++ + L+ EE
Sbjct: 180 DTDIYSFHSATEQEDLLSDIQQAI-RLQQQQQQQLQLQLQQQQQQQQLQ------GAEEP 232
Query: 976 APPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQG 1035
A PP + P + P G E PG+ + A +A + PE+L ++
Sbjct: 233 AAPPTAVSPQPGAFLGLDRFLLGPSGGAG-----EAPGSPDTEQALSALSDLPESLAAEP 287
Query: 1036 EVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAE 1095
++ SP P V E PS P + S P P EE
Sbjct: 288 REPQQPPSPGGLP-----VSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGA 342
Query: 1096 ALQEKEQDDTAAMLADFIDCP---PDDEKPP 1123
++E ++ A F D P P +E P
Sbjct: 343 GDTDEEGEEDA-----FEDAPRGSPGEEWAP 368
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 97.8 bits (242), Expect = 5e-20
Identities = 150/549 (27%), Positives = 193/549 (35%), Gaps = 116/549 (21%)
Query: 665 FHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPP----TTANHLGLSVPGLVSVP 720
F PP P + P A + G P G V S +P P A LG + V +
Sbjct: 372 FSPPEPGDTPTDEPDALYVACQG-QPKGGHVTSMQPKEPGPLQCEAKPLGKAG---VQLE 427
Query: 721 PRLLPGPENHRAGSNED-PILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEE--ASDVE 777
P+L A NE+ P+L P P + PP+E+ P + + EE AS +
Sbjct: 428 PQL-------EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP 480
Query: 778 --ISLESDSDDSVVIVPEGLPPLPPPPPSGA-TPPPIAPTGPPTASPPVPAKEEP----- 829
+ L ++S + P PL PPP S +P +P PP SPP PA E P
Sbjct: 481 EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
Query: 830 ---------EELPAAPGP--LPPPPPP------PPPVPGPVTLPPPQLVPEGTPGGGG-- 870
EE P +P P LP PPP PPP P++ PPP+ P P
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS-PPPEESPMSPPPEASRL 599
Query: 871 -PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929
PP E L S EE E ED EE E
Sbjct: 600 FPPFEESPL-------SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Query: 930 ------EFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAP--PPP- 980
EE L EE E + + E +P PPP
Sbjct: 653 LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712
Query: 981 ----TLP----PALPPPESP--------PKVQPEPEPEPGLLLEVEEPGTEEERGADTAP 1024
+LP P LP PE P P + P PE EP L EEP + P
Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE-EPHLSPRPEEPHLSPQA---EEP 768
Query: 1025 TLAPE-------ALPSQGEVEREGESPAAGPPPQEL-------------VEEEPSAPPTL 1064
L+P+ A+P + + + E P P P+EL V EEP P
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP 828
Query: 1065 LEEETEDGSDKVQPPPETPAEEEMETETEAEALQ---EKEQDDTAAMLADFIDCPPDDEK 1121
E S++ P P E + E E L EK ++ CP +E
Sbjct: 829 EESHLSPQSEEPCLSPR-PEESHLSPELEKPPLSPRPEKPPEEPG-------QCPAPEEL 880
Query: 1122 P--PPPTEP 1128
P PPP EP
Sbjct: 881 PLFPPPGEP 889
Score = 92.4 bits (228), Expect = 2e-18
Identities = 137/531 (25%), Positives = 178/531 (33%), Gaps = 90/531 (16%)
Query: 591 SPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAP 650
SP PPP +A L + L S EAL L PL P P +P
Sbjct: 456 SPTSPPP-----EASRLSPPPEELPASPL-PEALHLSRPLEES---PLSP--PPEESPLS 504
Query: 651 VPPPEAP-SPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709
PP +P SP P PP P PS P P A P+ PP + L
Sbjct: 505 PPPESSPFSPLEESPLSPPEESP-----PSPALETPLSPPPEASPL-----SPPFEESPL 554
Query: 710 GLSVPGLVSVPP----RLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAF 765
L + PP RL P PE E P+ P P + PP+ + F
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPE-------ESPMSPPPEESPMSPPPEAS-------RLF 600
Query: 766 VHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPI-APTGPPTASPPVP 824
+++ S PE P PPP S +PPP +P PP P+
Sbjct: 601 PPFEESPLSPP---------------PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645
Query: 825 AKEEPEELPAAP-----------GPLPPPPPPPPPVPGPVTL---PPPQLVPEGTPGGGG 870
E L P PL PPP P P P PPP+ P P
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Query: 871 P--PALEEDLTVININSSDEEEEEEEEE---EEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925
P P E+ L + + S EE + E E+ EE + +
Sbjct: 706 PASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQA 765
Query: 926 EEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPA 985
EE + E + EE + E L + EE P T P
Sbjct: 766 EEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSP-----------QPEELHLSPQTEEPH 814
Query: 986 LPPPESPPKVQPEPEPEPGLLLEVEEPG-TEEERGADTAPTLAPEALPSQGEVEREGESP 1044
L P P + P+PE E L + EEP + + +P L E P E+ E P
Sbjct: 815 LSPVPEEPCLSPQPE-ESHLSPQSEEPCLSPRPEESHLSPEL--EKPPLSPRPEKPPEEP 871
Query: 1045 AAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAE 1095
P P+EL P P+L E + PP +P EE+ E
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGE 922
Score = 84.7 bits (208), Expect = 4e-16
Identities = 145/551 (26%), Positives = 185/551 (33%), Gaps = 99/551 (17%)
Query: 582 LLLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCS-EALVTCAALTHPRVPPLQP 640
L L+ L SP PPP L LE S E AL P PP
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP--- 539
Query: 641 MGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARP 700
P +P+ PP SP PP P P S S P P PM S P S
Sbjct: 540 -----PEASPLSPPFEESPLSPPPEELPTSPPPEASRLS--PPPEESPM-SPPPEESPMS 591
Query: 701 GPPTTANHLGLSVPGLVSVPPR---LLPGPENHRAGS--NEDPILAPSGTPPPTIPPDET 755
PP + +S PP L P PE R + P+ P P + PP+ +
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
Query: 756 FGGRVPRPAFVHYDKEEASDVEISLESDSD-----DSVVIVPEGLPPLPPPPPSGATPPP 810
+P + + EE+ ES + + PE P PPP S A+PPP
Sbjct: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711
Query: 811 --IAPTGPPTASPPVPAKEEPEELPAAPGP-LPPPPPPPPPVPGPVTLPPPQLVPEGTPG 867
+ P SP +P EEP+ P + GP L P P P P P P L P+
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP---EEPHLSPQAEEP 768
Query: 868 GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE------EEYF 921
P E L + EE + E + EE + E+ EE
Sbjct: 769 HLSPQPEEPCLCAV-----PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823
Query: 922 EEEEEEEEEFEEEFEE-------EEGELEEEEE--------EEDEEEEEELEEVEDLEFG 966
+ EE + EE EE L E E E+ EE + E+L
Sbjct: 824 LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF 883
Query: 967 TAGGEV------------EEGAPP-------------------PPTLPP-ALPPPESPPK 994
GE E G PP P +PP LPPP SP
Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943
Query: 995 VQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELV 1054
P P L E+E P + +P AP E+P + PP
Sbjct: 944 TAAAP-PALSPLGELEYPFGAKGDSDPESPLAAPIL-----------ETPISPPPEANCT 991
Query: 1055 EEEPSAPPTLL 1065
+ EP PP +L
Sbjct: 992 DPEP-VPPMIL 1001
Score = 63.9 bits (154), Expect = 8e-10
Identities = 143/558 (25%), Positives = 189/558 (33%), Gaps = 129/558 (23%)
Query: 591 SPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQP------MGPT 644
SP PPP EDSL S L L P P L P + P
Sbjct: 705 SPASPPP-------------EDSL-----MSLPLEESPLLPLPEEPQLCPRSEGPHLSPR 746
Query: 645 CPTPAPVPPPEAP--SPFRAPPFHPPGPM-PSVGSMPSAGPMPSAGPMPSAGPVPSARPG 701
P P PE P SP P P P P + ++P + P P P
Sbjct: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHL 806
Query: 702 PPTTANHLGLSVPGLVSVP--PRLLPGPE-NHRAGSNEDPILAPSG-------------- 744
P T P L VP P L P PE +H + +E+P L+P
Sbjct: 807 SPQTEE------PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL 860
Query: 745 TPPPTIPPDETFGGRVPR--PAFVHYDKEEASDV--EISLESDSDDSVVIVPEGLPPLPP 800
+P P PP+E P P F + S + E +L + + +PE LP P
Sbjct: 861 SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPS 920
Query: 801 PPPS--------GATPPPIAP----TGPPTASP------PVPAK--EEPEELPAAP---G 837
PS PPP++P PP SP P AK +PE AAP
Sbjct: 921 GEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET 980
Query: 838 PLPPPP----------PP--PPPVPGPVTLP---------PPQ--------LVPEGTPGG 868
P+ PPP PP PP PG P PPQ LVP+ +P
Sbjct: 981 PISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPS 1040
Query: 869 G-GPPAL----EEDLTVIN--INSSDEEEEEEEEEEEEEEE-----EEEEEEDFEEEEED 916
PPAL L+ I + SDE E E E E+ E E D
Sbjct: 1041 QCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGD 1100
Query: 917 EEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGA 976
++F E+ L+ + + E + T G E
Sbjct: 1101 LSCPAPSPAPALDDF-SGLGEDTAPLDGIDAPGSQPEPGQ----------TPGSLASELK 1149
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
P L P P +P +V PE + G EE A T PTL + ++
Sbjct: 1150 GSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEIS 1209
Query: 1037 VEREGESPAAGPPPQELV 1054
+G++ A+ P + L+
Sbjct: 1210 NLSQGDASASFPGSEPLL 1227
Score = 62.8 bits (151), Expect = 2e-09
Identities = 149/617 (24%), Positives = 191/617 (30%), Gaps = 118/617 (19%)
Query: 590 PSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTP- 648
PSP PL+ +A L + +S E L T R+ P P P P
Sbjct: 528 PSPALETPLSPPPEASPLSPPFEESPLSP-PPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Query: 649 -APV-PPPEAPS---PFRAPPFHPPGPMPSVGSMPSAG---PMPSAGPMPSAGPVPSARP 700
+P+ PPPEA PF P PP + P A P P PM S P S
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM-SPPPEESPMS 645
Query: 701 GPPTTANHLGLSVPGLVSVPPRLLP-GPENHRAGSNEDPILAPSGTPP---PTIPPDETF 756
PP + L V +S PP P P + ++ P + PP PT PP E
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Query: 757 GGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVP-EGLPPLPPPPPSGATPPPIAPTG 815
P +DS++ +P E P LP P P P
Sbjct: 706 PASPP----------------------PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
Query: 816 PPTASPP--VPAKEEPEELPAAPGPLPPPPPPPP---PVPGPVTLPP----PQLVPEGTP 866
P P P EEP P A P P P P VP L P P L P+
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803
Query: 867 GGGGPPALEEDLTVIN----INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE 922
P E L+ + ++ EE + EE EE E E
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR 863
Query: 923 EEEEEEEEFEEEFEEE-----------------EGELEEEEEEEDEEEEEELEEVEDLEF 965
E+ EE + EE E L E E EEL E
Sbjct: 864 PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP 923
Query: 966 GTAGGEVEEGAPPPP-------TLPPALPP---------------------------PES 991
+ + PPP PPAL P P S
Sbjct: 924 SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS 983
Query: 992 PPKVQ--PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPP 1049
PP +PEP P ++L P + +P L P + + P PP
Sbjct: 984 PPPEANCTDPEPVPPMIL----PPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPP 1039
Query: 1050 PQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMET----ETEAEALQEKEQDDT 1105
Q P + P+ L KV + EMET E E AL+
Sbjct: 1040 SQCSPPALPLSVPSPLSP-----IGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL 1094
Query: 1106 AAMLADFIDCPPDDEKP 1122
+ + D + CP P
Sbjct: 1095 PSPMGD-LSCPAPSPAP 1110
Score = 57.8 bits (138), Expect = 6e-08
Identities = 79/286 (27%), Positives = 95/286 (33%), Gaps = 65/286 (22%)
Query: 633 PRVPPLQP---MGPTCPTPAPVPPPEAPSP---------FRAPPFHPPGPMPSVGSMPSA 680
PR P P + P CP+ + PE+P PPF V
Sbjct: 2234 PRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELG 2293
Query: 681 GPMPSAGPMPSAGPVPSARPGPPTTANHLG---LSVPGLVSVP--PR------------- 722
PS GP P+ G V S P++ HLG L P + P PR
Sbjct: 2294 ASSPSYGP-PNLGFVDS-----PSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGL 2347
Query: 723 ----------LLPGPENH----RAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHY 768
L P P +H R GS DP P TP P PP E+ PR
Sbjct: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSL---- 2403
Query: 769 DKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEE 828
+ S V S +S S PL P P S P +P P SP ++
Sbjct: 2404 PSDPFSRVPASPQSQSSSQ--------SPLTPRPLSAEAFCP-SPVTPRFQSPDPYSR-- 2452
Query: 829 PEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
P P + P P PP P P V L GG P AL
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAAL 2498
Score = 53.9 bits (128), Expect = 8e-07
Identities = 68/256 (26%), Positives = 88/256 (34%), Gaps = 43/256 (16%)
Query: 634 RVPPLQPMGPTCPTP---APVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMP 690
++PP P P AP P E P APP +PP P P+ P+ PM A P
Sbjct: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFP-TAPPTYPPYPSPT--GAPAQPPMLGASSRP 2218
Query: 691 SAGPVPSARPGPPTTANHLGLS-----VPGLVSVPPRLLPGPENHRAGSNEDPILAPS-- 743
AG PP T H + P S+ +P G +P+L+P
Sbjct: 2219 GAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPF 2278
Query: 744 --------------GTPPPTIPPDETFGGRVPRPAF-VHYDKEEASDVEISLESDSDDSV 788
G P+ P G V P+ H E ++ + +
Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNL--GFVDSPSSGTHLGGLELKTPDVFKAPLTPRAS 2336
Query: 789 VIVPE----GLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPP 844
+ P+ GL P PPP P P P+ P P P A PL P P
Sbjct: 2337 QVEPQSPGLGLRPQEPPPAQALAPSP--PSHPDIFRPGSYTD------PYAQPPLTPRPQ 2388
Query: 845 PPPPVPGPVTLPPPQL 860
PPPP LPP L
Sbjct: 2389 PPPP-ESCCALPPRSL 2403
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/76 (42%), Positives = 40/76 (52%), Gaps = 12/76 (15%)
Query: 792 PEGLPPLPPPPPSGATPP---PIAPTGPPTASPPVPAKEEPEELPAAPGPLP-----PPP 843
P+G P LP PP + +T P P+ PT PP +SP P + P +LP+ LP PP
Sbjct: 4283 PQGPPRLPAPPGALSTGPVLGPVHPT-PPPSSPQEP--KRPSQLPSPSSQLPTEAQLPPT 4339
Query: 844 PPPPPVP-GPVTLPPP 858
P P P GP PPP
Sbjct: 4340 HPGTPKPQGPTLEPPP 4355
Score = 48.9 bits (115), Expect = 3e-05
Identities = 91/401 (22%), Positives = 122/401 (30%), Gaps = 64/401 (15%)
Query: 682 PMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILA 741
P P A P P+ G PTT L S G + P +PGP++
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS------------ 2155
Query: 742 PSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPP 801
P E F P ++ + S D P GL P P
Sbjct: 2156 ----------PGELFLKLPP---------------QVPAQVPSQD-----PFGLAPAYPL 2185
Query: 802 PPSGATPPPI-APTGPPTASPPVPAKEEPEELPAA--PGPLPPPPP----PPPPVPGPVT 854
P T PP P PT +P P P A PG PP P P P
Sbjct: 2186 EPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFL 2245
Query: 855 LPP-PQL----VPEGTPGGGGPPALEEDLTVININSSDEE-EEEEEEEEEEEEEEEEEEE 908
P P L VPE +PG GG A E L+ S + E ++EE
Sbjct: 2246 KPRCPSLDNLAVPE-SPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNL 2304
Query: 909 DFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE-------EEEDEEEEEELEEVE 961
F + E + + F+ ++E + +E +
Sbjct: 2305 GFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPS 2364
Query: 962 DLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGAD 1021
+ G + A PP T P PPPES + P P P ++ +
Sbjct: 2365 HPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP 2424
Query: 1022 TAP-TLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAP 1061
P L+ EA R PP +P AP
Sbjct: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP 2465
Score = 48.1 bits (113), Expect = 5e-05
Identities = 165/738 (22%), Positives = 240/738 (32%), Gaps = 168/738 (22%)
Query: 446 AGMLQGGASGEALLTHLLSDISPPADALKLRSPRGSPDGSLQTGKPSAPKKLKLDVG-EA 504
+G G +SG ++ LS + PP+ P +PDGSL A ++ + E
Sbjct: 2590 SGSPLGPSSGSTGESYGLSPLRPPSVL-----PPPAPDGSLPYLSHGASQRSGITSPVEK 2644
Query: 505 MAPPSHRKGDSNANSDVCAA---ALRGLSRTILMCGPLIKEETHRRLHDLVLPLVMGVQQ 561
P G S A +++ + GLS+T L K+ +RL +L++ +Q+
Sbjct: 2645 REDPGTGMGSSLATAELPGTQDPGMSGLSQT-----ELEKQRQRQRLRELLIR--QQIQR 2697
Query: 562 GEVLGSSPYTSSRCRRELYCLLLALLLAPSPRCPPPLACALQAFSLGQRE--DSLEVSSF 619
+ R +E + P P + A + S GQ + + SS
Sbjct: 2698 NTL---------RQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL 2748
Query: 620 CSEALVTCAALTHPRVPPLQPMGPTC-PTPAPV-------PPPEAPSPFR---------A 662
+PP + GP P P PPP PS +
Sbjct: 2749 VG-------------LPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS 2795
Query: 663 PPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSAR----------PGPPTTANHLGLS 712
F+ P P GS+P A S R PGP LG
Sbjct: 2796 QAFYQRAPYP--GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSP 2853
Query: 713 VPGL---VSVPPRLLPGPENH----RAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAF 765
+ G+ + P +PGP N L P GTP P P + RP F
Sbjct: 2854 LAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQ-------RPRF 2906
Query: 766 VHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPA 825
S+D + PEGL L SG PP P+ PP
Sbjct: 2907 YPV---------------SEDPHRLAPEGLRGLAV---SGL--PPQKPSAPPAP------ 2940
Query: 826 KEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININS 885
EL + P P P P + PP G P P ALE
Sbjct: 2941 -----ELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPN---PLALEAGKLPCEDPE 2992
Query: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL--- 942
D++ + + E++EE + +DE E E + ++ +E +L
Sbjct: 2993 LDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAY 3052
Query: 943 -EEEEEEEDEEE--EEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEP 999
+ E + D+++ E L VE + G P P L P E PP
Sbjct: 3053 TDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGP-----LGPEERPPPAADAS 3107
Query: 1000 EPE-----PGLLLEVEEPGTEEERGADTAPTLAPEALP---------------------- 1032
EP P + +VEE G T T E P
Sbjct: 3108 EPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTR 3167
Query: 1033 -------SQGEVEREGESPAAGPPPQELVEEEPSAPP---TLLEE-ETEDGSDKVQPPPE 1081
S G + A G PP L+ P + P +LLE+ E E G+ + P
Sbjct: 3168 MGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPA 3227
Query: 1082 TPAEE--EMETETEAEAL 1097
+E +ME+ A L
Sbjct: 3228 ASGDELDKMESSLVASEL 3245
Score = 46.6 bits (109), Expect = 1e-04
Identities = 96/385 (24%), Positives = 120/385 (31%), Gaps = 71/385 (18%)
Query: 548 LHDLVLPLVMGVQQGE----VLGSSPYTSSRCRRELYCLLLALLLAPSPRCPPPLACALQ 603
L +L +P GV G+ +L P+ SR E+ L A SP PP +
Sbjct: 2252 LDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELG---ASSPSYGPPNLGFVD 2308
Query: 604 AFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPE---APSPF 660
+ S G LE+ + V A LT PR ++P P PPP APSP
Sbjct: 2309 SPSSGTHLGGLELKT----PDVFKAPLT-PRASQVEPQSPGLGLRPQEPPPAQALAPSPP 2363
Query: 661 RAPPFHPPGPMPSVGSMPSAGPMPSAGP-----------MPS-------AGPVPSARPGP 702
P PG + P P P P +PS A P +
Sbjct: 2364 SHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQS 2423
Query: 703 PTTANHLGLSVPGLVSVPPRLLPGPENHRAGS---NEDPILAPSGTPPPTIPPDETF--- 756
P T L V PR R S + DP AP PP PP+ F
Sbjct: 2424 PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF-APLHKPPRPQPPEVAFKAG 2482
Query: 757 --------GGRVPR-----PAFVHYDKEEASDVEISLESDSDDSVVIVPE---------- 793
G P PA + K + + S + V P
Sbjct: 2483 SLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAV 2542
Query: 794 GLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPV 853
G P L PP P PPP P K + A G P P P G
Sbjct: 2543 GEPSLKPPVPQPGLPPPHG-INSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGST 2601
Query: 854 -------TLPPPQLVPEGTPGGGGP 871
L PP ++P P G P
Sbjct: 2602 GESYGLSPLRPPSVLPPPAPDGSLP 2626
Score = 44.7 bits (104), Expect = 5e-04
Identities = 80/344 (23%), Positives = 109/344 (31%), Gaps = 48/344 (13%)
Query: 802 PPSGATPPPIAPTG-----PPTASPPVPAKEEPEELPAAP----GPLPPPPPPPPPVPGP 852
PP+G+ P P +P PP VP+++ PA P P PP PP P P
Sbjct: 2145 PPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTG 2204
Query: 853 VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912
PP L PG G P + + + + + E
Sbjct: 2205 APAQPPMLGASSRPGAGQPGEFH-----TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPE 2259
Query: 913 EEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEV 972
E F E + E + EE L V+ GT G +
Sbjct: 2260 SPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGL 2319
Query: 973 EEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
E P P +P Q EP+ PGL L +EP A LAP P
Sbjct: 2320 ELKTP------DVFKAPLTPRASQVEPQ-SPGLGLRPQEP--------PPAQALAPSP-P 2363
Query: 1033 SQGEVEREGE--SPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMET 1090
S ++ R G P A PP + P PP S PP P++
Sbjct: 2364 SHPDIFRPGSYTDPYAQPP----LTPRPQPPP--------PESCCALPPRSLPSDPFSRV 2411
Query: 1091 ETEAEALQEKEQDDTAAMLADFIDCP----PDDEKPPPPTEPDS 1130
++ + T L+ CP P + P P + P S
Sbjct: 2412 PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPS 2455
Score = 43.9 bits (102), Expect = 9e-04
Identities = 26/66 (39%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 798 LPPPPPSGATPPPIAPTGPPTASPP----VPAKEEPEELPAAPGPLPPPPPPPPPVPGPV 853
L PPP +PPP +P P ASPP V EP P P PLP P P P
Sbjct: 4906 LSAPPPEEPSPPP-SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 854 TLPPPQ 859
PP +
Sbjct: 4965 ARPPEE 4970
Score = 43.5 bits (101), Expect = 0.001
Identities = 56/221 (25%), Positives = 71/221 (32%), Gaps = 64/221 (28%)
Query: 661 RAPPFHPPGPMPS-----VGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPG 715
+ PP+ PG S +G P G P P GP+ GP
Sbjct: 4239 QTPPYQEPGTQTSPLQGLLGCQPQLGGFPG----PQTGPLQELGAGPRPQG--------- 4285
Query: 716 LVSVPPRLLPGPENHRAGSNEDPILAP-SGTPPPTIPPDETFGGRVPRPAFVHYDKEEAS 774
PPRL P G P+L P TPPP+ P + ++P P+
Sbjct: 4286 ----PPRLPAPPGALSTG----PVLGPVHPTPPPSSPQEPKRPSQLPSPS---------- 4327
Query: 775 DVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPT--GPPTASPPVPAKEEPEEL 832
S + LPP P TP P PT PP P A+
Sbjct: 4328 ------------SQLPTEAQLPPTHP-----GTPKPQGPTLEPPPGRVSPAAAQLADTLF 4370
Query: 833 PAAPGPLPPP--------PPPPPPVPGPVTLPPPQLVPEGT 865
GP PP P VPG + Q+VPE +
Sbjct: 4371 SKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEAS 4411
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 14/109 (12%)
Query: 806 ATPPPIAPTGPPTASPPVPAKEEPE---ELPAAPGPLPPPPPPPPPVPGPVTL-PPPQLV 861
+ PPP P+ PP+ P PA E ELP P PP P P P P + P P+
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 862 PEGTPGGGGPPALEE----------DLTVININSSDEEEEEEEEEEEEE 900
P PP L++ L I S +E+E E E E+
Sbjct: 4967 PPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQ 5015
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/70 (38%), Positives = 32/70 (45%), Gaps = 11/70 (15%)
Query: 796 PPLPPPPPSGATPPPIA-PTGP-------PTASPPVPAKEEPEELPAAPGPLPPPPPPPP 847
P P PPPS P P + PT P P A PPVP+ P L ++P P P P
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS---PLPLASSPESARPKPRARP 4967
Query: 848 PVPGPVTLPP 857
P G + PP
Sbjct: 4968 PEEGEDSRPP 4977
Score = 40.0 bits (92), Expect = 0.013
Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
Query: 595 PPPLACALQAFSLGQREDSLEVSSFCSEALVTCAAL--THPRVPPLQPMGPTCPTPAPVP 652
P P LQ G R AL T L HP PP P P P+ P P
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326
Query: 653 PPEAPSPFRAPPFHPPGPMP 672
+ P+ + PP HP P P
Sbjct: 4327 SSQLPTEAQLPPTHPGTPKP 4346
Score = 37.4 bits (85), Expect = 0.081
Identities = 72/278 (25%), Positives = 89/278 (32%), Gaps = 64/278 (23%)
Query: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPS-----AGPVPSARPGPPT 704
P P P+ S PP PG S+ S G + S A VP P
Sbjct: 4080 PQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSV 4139
Query: 705 ---------TANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPIL-APSGTPPPTIPPD- 753
T N LG P ++ P + GP+ + G P+L + G P I P
Sbjct: 4140 SLGDQPGSMTQNLLGPQQP-MLERPMQNNTGPQPPKPG----PVLQSGQGLPGVGIMPTV 4194
Query: 754 -----ETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPP------- 801
+ G P H ++ ++ L V + PP P
Sbjct: 4195 GQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQ-TPPYQEPGTQTSPL 4253
Query: 802 -------PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPL----------PPPPP 844
P G P P TGP P + P LPA PG L P PPP
Sbjct: 4254 QGLLGCQPQLGGFPGP--QTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP 4311
Query: 845 PPPPVP-GPVTLPPP--------QLVP--EGTPGGGGP 871
P P P LP P QL P GTP GP
Sbjct: 4312 SSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
Score = 34.7 bits (78), Expect = 0.53
Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 10/62 (16%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAP------SPFRAPPFHPPGPMPSVGSMPSAGPMPSA 686
P P P P P+PA PP P P PP P P+P S SA P P A
Sbjct: 4910 PPEEPSPPPSPLAPSPA--SPPTEPLVELPTEPLAEPPV--PSPLPLASSPESARPKPRA 4965
Query: 687 GP 688
P
Sbjct: 4966 RP 4967
Score = 34.3 bits (77), Expect = 0.69
Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 7/107 (6%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP---EALPS 1033
P PT PP+ P+ P + P P L E + P T PTL P P+
Sbjct: 4304 PVHPTPPPS--SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPA 4361
Query: 1034 QGEVEREGESPAAGP--PPQELVEEEPSAPPTLLEEETEDGSDKVQP 1078
++ S GP PP L E + +L+ + + +V P
Sbjct: 4362 AAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVP 4408
Score = 33.9 bits (76), Expect = 0.90
Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 38/196 (19%)
Query: 966 GTAGGEVEEGAPPPPTLPPALPPPESP----PKVQPEPEPEPGLLLEVEEPGTEEERGAD 1021
G + G E P PP++ PP +P P + G+ VE+ E+ G
Sbjct: 2595 GPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEK---REDPGTG 2651
Query: 1022 TAPTLAPEALP----------SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEE--T 1069
+LA LP SQ E+E++ + +EL+ + TL +E+
Sbjct: 2652 MGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRL----RELLIRQQIQRNTLRQEKETA 2707
Query: 1070 EDGSDKVQPP------PETPAEEEMET-ETEAEALQEKEQ------DDTAAMLADFIDCP 1116
+ V PP P +PA E++ +T Q+K + + P
Sbjct: 2708 AAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFP 2767
Query: 1117 PDD--EKPPPPTEPDS 1130
DD +PPPP P S
Sbjct: 2768 SDDRLSRPPPPATPSS 2783
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/95 (31%), Positives = 36/95 (37%), Gaps = 18/95 (18%)
Query: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEV-EEPGTEEERGADTAPTLAPE 1029
+V + + PPP P P P +P P EP L+E+ EP E P
Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAPSPASPPTEP----LVELPTEPLAEPP---------VPS 4948
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTL 1064
LP E P A PP E E S PP L
Sbjct: 4949 PLPLASSPESARPKPRARPPE----EGEDSRPPRL 4979
Score = 33.5 bits (75), Expect = 1.2
Identities = 23/72 (31%), Positives = 25/72 (34%), Gaps = 7/72 (9%)
Query: 639 QPMGPTCPTPAPVPPPEAPSPFRAP-------PFHPPGPMPSVGSMPSAGPMPSAGPMPS 691
Q P P+P P P APSP P P P P +P A SA P P
Sbjct: 4905 QLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 692 AGPVPSARPGPP 703
A P P
Sbjct: 4965 ARPPEEGEDSRP 4976
Score = 31.2 bits (69), Expect = 5.8
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 17/90 (18%)
Query: 633 PRVPPLQPMGP----TCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGP 688
P+ PP P P T P PV P PP P PS P PS+
Sbjct: 4283 PQGPPRLPAPPGALSTGPVLGPVHPT------------PPPSSPQEPKRPSQLPSPSS-Q 4329
Query: 689 MPSAGPVPSARPGPPTTANHLGLSVPGLVS 718
+P+ +P PG P PG VS
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
Score = 30.8 bits (68), Expect = 7.6
Identities = 73/315 (23%), Positives = 104/315 (33%), Gaps = 46/315 (14%)
Query: 466 ISPPADALKLRSPRGSPDGSLQTGKPSAPKKLKLDVGEAMAPPS-----------HRKGD 514
+SP + L L SP G P S Q P + A APP+ KGD
Sbjct: 908 LSPLPEELPL-SPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGD 966
Query: 515 SNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHDLVLPLVMGVQQGEVLG-SSPYTSS 573
S+ S + A L T + P E + + V P+++ G +G +SP
Sbjct: 967 SDPESPLAAPILE----TPISPPP----EANCTDPEPVPPMILPPSPGSPVGPASPILME 1018
Query: 574 RCRRELYCLLLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHP 633
+ LL L+ P+ PP C+ A L + V+ A H
Sbjct: 1019 PLPPQCSPLLQHSLV---PQNSPPSQCSPPALPLSVPSPLSPIGKVVG---VSDEAELH- 1071
Query: 634 RVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAG 693
+ + P CP P PSP P P P++ G P+
Sbjct: 1072 EMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLG--EDTAPLDGI- 1128
Query: 694 PVPSARPGPPTTANHLGLSVPG---------LVSVPPRLLPGPENHRAG------SNEDP 738
P ++P P T L + G L V P + AG E+P
Sbjct: 1129 DAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEP 1188
Query: 739 ILAPSGTPPPTIPPD 753
+ TPP I D
Sbjct: 1189 RAPVAPTPPTLIKSD 1203
Score = 30.8 bits (68), Expect = 7.6
Identities = 37/149 (24%), Positives = 54/149 (36%), Gaps = 26/149 (17%)
Query: 966 GTAGGEVEEGAPPPPTLPP-----ALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA 1020
G G + + G P P P A P P+ PP++ P P PG L
Sbjct: 4255 GLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL---PAP-PGAL-------------- 4296
Query: 1021 DTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
T P L P +E + P+ P P + E PPT G ++PPP
Sbjct: 4297 STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG-PTLEPPP 4355
Query: 1081 --ETPAEEEMETETEAEALQEKEQDDTAA 1107
+PA ++ ++ L + D A
Sbjct: 4356 GRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 94.7 bits (234), Expect = 4e-19
Identities = 79/261 (30%), Positives = 103/261 (39%), Gaps = 36/261 (13%)
Query: 630 LTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPM 689
+T PR +GP +P P P A +APP P P S + A P+P A P
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS 344
Query: 690 PSAGPVPSARPGPPTTANHLGLSVPG--LVSVPPRLLPGPENHRAGSNEDPILAPSGTPP 747
PSA P P PP T + G + LP P L+P TPP
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-----------LSPLATPP 393
Query: 748 PTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDS-------VVIVPEGLPPLPP 800
P PP + P AS L + S + ++ P PP PP
Sbjct: 394 PQAPP------ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447
Query: 801 --PPPSGATPPPIAPTG-PPTASPP---VPAKEEPEELPAAPGPLPPPPPPPPPVPGPVT 854
P S PP++P+ PP+ +PP P + P PA+P P+ P PPP P P+
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLA 506
Query: 855 LPPPQLV---PEGTPGGGGPP 872
PP QL P+ P PP
Sbjct: 507 APPLQLAKPPPQAPPALATPP 527
Score = 80.9 bits (198), Expect = 6e-15
Identities = 83/295 (28%), Positives = 105/295 (35%), Gaps = 71/295 (24%)
Query: 590 PSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQ-PMGPTCP-- 646
PSP PPL+ A Q ++L V + A + P PP+Q P P
Sbjct: 409 PSPPASPPLSPL--ATPSPQAPNALAVH-------LLQAPFSPPPSPPVQAPFSPPASPP 459
Query: 647 -TPAPVPPPEAPSPFRAPPFH-PPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPT 704
+P+ PP +AP APP PP P S PSA P P A P +A P+ A+P P
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Query: 705 TANHLGLSVPGLVSVPPRLLPGPENHRAGS-----NEDPILAPSGTPPPTIPPDETFGGR 759
P L + P + LP P G + ++P TPPP PP
Sbjct: 520 P--------PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP------- 564
Query: 760 VPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTA 819
++ L +PP PP A+P AP PPT
Sbjct: 565 ------------------------------VLAAPLLQVPPSPP--ASPTLQAPRRPPTP 592
Query: 820 SPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
P L APGP PPPP TL P L + P L
Sbjct: 593 GPDTSVSGPRLTLALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 642
Score = 79.0 bits (193), Expect = 2e-14
Identities = 98/318 (30%), Positives = 117/318 (36%), Gaps = 76/318 (23%)
Query: 584 LALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQ--PM 641
LA+ L +P PPP FS ++ S+A + AA PPLQ P
Sbjct: 431 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA------PPLQVPPS 484
Query: 642 GPTCP--TPAPVPPPEAPSPFRAPPFH--------PPG----PMPSVGSMPSAGP----- 682
P P +P+ PPP+AP P APP PP P+ ++ S P++ P
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 683 MPSAG-PM-PSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRL-------LPGPENHRAG 733
PSA PM P A P P A PP A L L VP P L PGP+ +G
Sbjct: 545 SPSASLPMSPLATPPPQA---PPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600
Query: 734 SNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPE 793
LAP PPP+ P T G P + S E DS PE
Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSG----PDLAGHSSSATSTPEELRGYDSG------PE 650
Query: 794 GLPPLPPPPP-----------SGATPPPIAPTGPPTASPPVPAK---------------E 827
G PPP S PP+A G P A P P E
Sbjct: 651 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 710
Query: 828 EPEELPAAPGPLPPPPPP 845
PE APG L P P P
Sbjct: 711 GPESATPAPGALDPGPSP 728
Score = 78.2 bits (191), Expect = 4e-14
Identities = 115/452 (25%), Positives = 155/452 (34%), Gaps = 113/452 (25%)
Query: 470 ADALKLRSP-RGSPDGSLQTGKPSAPKKLKLDVGEAMAPPSHRKGDSNANSDVCAAALRG 528
+ A L SP R P P+ P + K +A+ PP +A A AL
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA-----APALGP 298
Query: 529 LSRTILMCGPLIKEETHRRLHDLVLPLVMGVQQGEVLGSSPYTSSRCRRELYCLLLALL- 587
LS + PL L P L ++P++SS L C L L
Sbjct: 299 LSSS-----PLATPSPSAALQSQAPP---------TLPATPHSSS-----LTCQLATPLP 339
Query: 588 -LAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCP 646
PSP PP L + + + + S +A T + L P + PL P P
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA--THSFLPSPPLSPLATPPPQAP 397
Query: 647 TPAPVPPPEAP-SPFRAPPFHPPG-PMPSVGSMPSAGPMPSAGPMPSAGPV-----PSAR 699
+PP +AP SP +PP P P P + + + + P + PV P A
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 700 PGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGR 759
P +A + P L + P ++ P P P ++PS TPPP PP
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPP-------ASPPMSPSATPPPQAPP------- 503
Query: 760 VPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL----PPP--PPSGATPPPIAP 813
P PPL PPP PP+ ATPP A
Sbjct: 504 --------------------------------PLAAPPLQLAKPPPQAPPALATPPLQAL 531
Query: 814 TGPPTASPPVPAKEEPEELPAAPGPLPPPPPPP------------------------PPV 849
PP + P LP +P PPP PP PP
Sbjct: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 591
Query: 850 PGPVT-LPPPQLVPEGTPGGGGPPALEEDLTV 880
PGP T + P+L PG PP+ T+
Sbjct: 592 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Score = 57.0 bits (136), Expect = 1e-07
Identities = 98/403 (24%), Positives = 133/403 (33%), Gaps = 122/403 (30%)
Query: 591 SPRCPPPLACA----LQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCP 646
SPR PPP+ A L A R+ E + A + +A PR P + G +
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA---PRAGPTRSAGTSSR 88
Query: 647 TPAPVPPPE-----AP-----------SPFRAPPFHPPGPM------------------- 671
PA PP AP SP RA PGP+
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148
Query: 672 --PSVGSMPSAGPMPSAGPMP------------SAG-------PVPSARPGPPTTANHLG 710
P ++ + ++GP P +AG P PSARP PPT
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 711 LSVPGLVSVPPRL------------LPGPENHRAGSNEDPILAPS-------GTPPPTIP 751
+S S L P + S+ P+ +P+ GTP
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 752 PDE--TFGGRVPRPAFVHYDKEEASDV--------------EISLESDSDDSVVIVPEG- 794
P + G + RP V +++A+ +L+S + ++ P
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSS 328
Query: 795 ------LPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEE--PEELPAAPGPLPPPP--- 843
PLP PPS + PP + P A+PP A L A LP PP
Sbjct: 329 SLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 388
Query: 844 --PPPPPVPGPVTLPP----------PQLVPEGTPGGGGPPAL 874
PPP P + LPP P L P TP P AL
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 431
Score = 47.0 bits (110), Expect = 1e-04
Identities = 42/161 (26%), Positives = 57/161 (35%), Gaps = 29/161 (18%)
Query: 976 APP--PPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA----PE 1029
+PP PP P A PPP++PP + P L++ +P + T P A P
Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPP-------LQLAKPPPQAPPALATPPLQALPSPPA 536
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089
+ P Q SP+A P L P APP L + +Q PP PA ++
Sbjct: 537 SFPGQAPF-----SPSASLPMSPLATPPPQAPPVL-------AAPLLQVPPSPPASPTLQ 584
Query: 1090 TETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
+ PP PPP P S
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPP----PPPSRSPSS 621
Score = 42.7 bits (99), Expect = 0.002
Identities = 73/283 (25%), Positives = 88/283 (31%), Gaps = 59/283 (20%)
Query: 643 PTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSA------------GPMPSAGPMP 690
P TP P P P P G +VG P A P AGP
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 691 SAGPV---PSARP---GPPTTANHLGLSVPGLVSVPPR----LLPGPENHR--------- 731
SAG P++RP G A + PG VS P R PGP +
Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141
Query: 732 ----------------AGSNEDPILAPSGTPPPTIPPDETFGGR---VPRPAFVHYDKEE 772
AG+ D GTP P + G +PRPA +
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
Query: 773 ASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEEL 832
S+ S S+ S E P P +G P +S P
Sbjct: 202 TEGPRKSVSSASEHSTT---EPSPAARRRPSAGGGLQ--RPASRSLSSSATPLSSPARSG 256
Query: 833 PAAPG-PLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
P+A G P P P P G L PPQ+ P P PAL
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTP---PRKDAAPAL 296
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 977 PPPPTLPPALPPPESPP-------KVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
P PP P A PPP++PP + P P P L + P + AP
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS-PLATPSPQAPNALAVHLLQAPF 440
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM 1088
+ P V+ SP A PP APP+L + +Q PP PA M
Sbjct: 441 SPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSL-------AAPPLQVPPSPPASPPM 491
Score = 39.7 bits (91), Expect = 0.016
Identities = 38/160 (23%), Positives = 48/160 (30%), Gaps = 18/160 (11%)
Query: 976 APPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQG 1035
APP P+ PP+L SPP P + P + +P L+P A P
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395
Query: 1036 EVE-------REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM 1088
+ SP A PP L P AP L + PPP P +
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ---APFSPPPSPPVQAPF 452
Query: 1089 ETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
A + PP P PP P
Sbjct: 453 SPPASPPVSPSATPPSQA---PPSLAAPPLQVPPSPPASP 489
Score = 35.4 bits (80), Expect = 0.31
Identities = 27/103 (26%), Positives = 35/103 (33%), Gaps = 14/103 (13%)
Query: 976 APPPPTLPPALP---------PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL 1026
A P P P AL PP SPP P P + P ++ P
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
Query: 1027 APEALPSQGEVEREGESPAAGP-----PPQELVEEEPSAPPTL 1064
P + P+ + P P PP +L + P APP L
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523
Score = 35.0 bits (79), Expect = 0.40
Identities = 41/175 (23%), Positives = 57/175 (32%), Gaps = 44/175 (25%)
Query: 977 PPPPTLPPA-----------------LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERG 1019
P PP PP+ LP P P P P+ P L L P +
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL----PPLQAPPS 410
Query: 1020 ADTAPTLAPEALPSQGEVEREG----ESPAAGP--PPQELVEEEPSAPPTLLEEETEDGS 1073
+P L+P A PS ++P + P PP + P++PP S
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV---------S 461
Query: 1074 DKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
PP + P A LQ + ++ PP + PPP P
Sbjct: 462 PSATPPSQAP------PSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAP 508
Score = 34.7 bits (78), Expect = 0.53
Identities = 40/164 (24%), Positives = 52/164 (31%), Gaps = 28/164 (17%)
Query: 966 GTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT 1025
GT P P L PP +PP+ P P + P + PT
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT 320
Query: 1026 LAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAE 1085
L A P + + +P PP PSAPP+L + PP TP
Sbjct: 321 L--PATPHSSSLTCQLATPLPLAPP------SPSAPPSL---------QTLPSPPATP-P 362
Query: 1086 EEMETETEAEALQEKEQDDTAAMLADFIDCPP-DDEKPPPPTEP 1128
+ T + LQ F+ PP PPP P
Sbjct: 363 SQATTSLGSPTLQATH---------SFLPSPPLSPLATPPPQAP 397
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 92.4 bits (228), Expect = 2e-18
Identities = 86/223 (38%), Positives = 100/223 (44%), Gaps = 21/223 (9%)
Query: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEE-----DEEEYFEEEEEEEEEFEEEFEEEEGE 941
+ EEEEEE E EEEE E EEEE EEEE +EE E EEE EE E E EEEEGE
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 942 LEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP 1001
E EEE E E EEEE E E E G GE EEG E + + E E
Sbjct: 885 GEGEEEGEGEGEEEE-GEGEGEEEGEGEGEEEEGEG---------KGEEEGEEGEGEGEE 934
Query: 1002 EPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAP 1061
E G + G EE + E +GE E E E G + EEE
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEW------EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988
Query: 1062 PTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
EE E+G ++ + E E E E E E E E E+ +
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031
Score = 85.5 bits (210), Expect = 3e-16
Identities = 79/218 (36%), Positives = 100/218 (45%), Gaps = 33/218 (15%)
Query: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
EEEE + EEEEE+E E +EE + EE E + E+ E ++EE +EE EEEG+ E EE
Sbjct: 739 EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEE 798
Query: 948 EEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLL 1007
EE E EE EE ++E GGEVEEG K + E E E G
Sbjct: 799 EETEGRGEEKEEGGEVE----GGEVEEG------------------KGEREEEEEEGEGE 836
Query: 1008 EVEEPGTEEE-RGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLE 1066
E E G EEE G + E +GE E EGE E EEE E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEG-----EGEEEEGEG-----E 886
Query: 1067 EETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
E E + + E EEE E E E E + K +++
Sbjct: 887 GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEE 924
Score = 80.9 bits (198), Expect = 6e-15
Identities = 83/221 (37%), Positives = 98/221 (44%), Gaps = 21/221 (9%)
Query: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
E EEEE E EE+EE E E E EE E EEEE E EE E E EEEEGE EEEE
Sbjct: 795 EGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG 854
Query: 948 E-EDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLL 1006
E + EEE EE E E+ E G GE EEG E + + E E E G
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEG------------EGEGEEEGEGEGEEEEG-E 901
Query: 1007 LEVEEPGT---EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPT 1063
E EE G EEE G E E E EGE G + EEE
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE----GEDGEGEGEEEEGEWEG 957
Query: 1064 LLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
EE +G ++ + E E E E E E +E+ +++
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Score = 77.8 bits (190), Expect = 5e-14
Identities = 86/220 (39%), Positives = 95/220 (43%), Gaps = 46/220 (20%)
Query: 863 EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE 922
EG G G EE EEE EE E E EEEE E E ED E E E+EE +E
Sbjct: 903 EGEEEGEGEGEEEEG------EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956
Query: 923 EEEEE-----EEEFEEEFEEEEGELEEEEEE-EDEEEEEELEEVEDLEFGTAG-GEVEEG 975
EEEE EEE E E EE EGE EEEE E E EEEE E E E+ E G GE EE
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE- 1015
Query: 976 APPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQG 1035
E +V+ E E E G EE G EE
Sbjct: 1016 --------------EEEGEVEGEVEGEEGEGEGEEEEGEEEGE----------------- 1044
Query: 1036 EVEREGESPAAGPPPQELVEEEPSAPPTLLEE-ETEDGSD 1074
E E+EGE +E EEE T EE E +DG +
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084
Score = 76.6 bits (187), Expect = 1e-13
Identities = 71/218 (32%), Positives = 96/218 (44%), Gaps = 6/218 (2%)
Query: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
E E E E+E E+EE ++ D EE+E+ E E ++E +E EE EEE GE EEEE
Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQ-GHQKERNQEMEEGGEEEHGEGEEEEG 743
Query: 948 EEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLL 1007
+ +EEEE+E E E+ E GE E+ A K + E + G
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERA----GKEEKGEEEGDQGEGEEE 799
Query: 1008 EVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE-SPAAGPPPQELVEEEPSAPPTLLE 1066
E E G E+E G + E + E E EGE G +E E E E
Sbjct: 800 ETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE 859
Query: 1067 EETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
EE E+G + + EE E E E E E E ++
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Score = 71.6 bits (174), Expect = 4e-12
Identities = 85/247 (34%), Positives = 100/247 (40%), Gaps = 43/247 (17%)
Query: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE---------EEYFEEE------EEEEEEF 931
D EEEEE+E E +EE E EE E E+EE E EE EEE EEEE E
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803
Query: 932 EEEFEEEEGELE---------EEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL 982
E +EE GE+E E EEEE+E E EE E + E G GE EEG
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE--GEEEEGEGKGEEE 861
Query: 983 PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREG- 1041
E + + E E E G E G EE G E +GE E EG
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEG-----EGEGEEEGEGEG-------EEEEGEGEGEEEGE 909
Query: 1042 ----ESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL 1097
E G +E E E E E EDG + + EE E E E E
Sbjct: 910 GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969
Query: 1098 QEKEQDD 1104
E E ++
Sbjct: 970 GEGEGEE 976
Score = 63.2 bits (152), Expect = 1e-09
Identities = 38/79 (48%), Positives = 49/79 (62%), Gaps = 1/79 (1%)
Query: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
+EEEE E E E E EE E E E+ E EEE EE E E EE EE EEEEG+ +E
Sbjct: 1014 EEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETG 1073
Query: 947 EEEDEEEE-EELEEVEDLE 964
EEE+E ++ EE ++V ++
Sbjct: 1074 EEENERQDGEEYKKVSKIK 1092
Score = 47.8 bits (112), Expect = 6e-05
Identities = 62/247 (25%), Positives = 94/247 (38%), Gaps = 31/247 (12%)
Query: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933
L +D + + SDE EE E +E + ++ + F + E F +EE E E +E
Sbjct: 532 LTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKE 591
Query: 934 EFEEEEGELEEEEEEEDEEEEEEL-----EEVEDLEFG-TAGGEVEEGAPPPPTLPPALP 987
E+ +G EE+E E EE ++ E+ E L T EV EG ++
Sbjct: 592 GAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGK------AKSVG 645
Query: 988 PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGES---- 1043
E P+ + + E G E E+G E +GE+ER GE
Sbjct: 646 EAEDGPEGRGDGTCEEGSSGAEHWQDEEREKG---------EKDKGRGEMERPGEGEKEL 696
Query: 1044 ------PAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL 1097
QE E E +E E G ++ E + E E E E E
Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK 756
Query: 1098 QEKEQDD 1104
+E E ++
Sbjct: 757 EEGEGEE 763
Score = 32.0 bits (71), Expect = 3.4
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 18/181 (9%)
Query: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGE-VEEG---APPPPTLPPALP 987
+++ ++ GEL ++ + ++ +E EE+ +++ G A + V +G P T+
Sbjct: 522 KQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSD 581
Query: 988 PPESPPKVQPEPEPEPGLLLEVEE----------PGTEEERGADTAPTLAPEALPSQGEV 1037
P+ + E G +E +E G +E+ + L +A S+G+
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKA 641
Query: 1038 EREGESPAAGPPPQ--ELVEEEPSAPPTLLEEETEDG-SDKVQPPPETPAEEEMETETEA 1094
+ GE+ GP + EE S +EE E G DK + E P E E E +
Sbjct: 642 KSVGEA-EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKE 700
Query: 1095 E 1095
E
Sbjct: 701 E 701
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 91.3 bits (225), Expect = 5e-18
Identities = 103/380 (27%), Positives = 132/380 (34%), Gaps = 102/380 (26%)
Query: 783 DSDDSVVIVPE----GLPPLPPPPPS----------GATPPPIAPTGPPT---------- 818
+S+D + +V E P+P P PS G T P + + PT
Sbjct: 121 ESEDMLELVAEVRIGDRDPIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTG 180
Query: 819 ----ASPPVP--AKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQL-----VPEGTPG 867
A PP P A P P++ P PPPPPPPP P P P P+
Sbjct: 181 DGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAP---PAPRFDIYDPFHPTDEA 237
Query: 868 GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEE- 926
PPA E+ S+ EEEEEEEEEEE+ EE+EE+EE +
Sbjct: 238 YSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRI 297
Query: 927 --------EEEEFEEEFEEEEGELEEEEEEE---------------------------DE 951
++ ++F +E + + +
Sbjct: 298 SETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGT 357
Query: 952 EEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEE 1011
E E E +E TAGG A PPP LPP E VQPE EP L L +
Sbjct: 358 EAEACREGKVSVEVVTAGG----AALPPPLLPPGDSEIEEGEIVQPEEEPR--LALSLFR 411
Query: 1012 PGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETED 1071
PG G PT A A +P A P PQ P L D
Sbjct: 412 PG-----GRAARPTPAASA------------TPTAQPLPQPPAPRAPEGDDFLSLHAESD 454
Query: 1072 GSDKVQ-----PPPETPAEE 1086
G +Q P P PA +
Sbjct: 455 GEGALQVDLGEPAPAPPAAD 474
Score = 53.1 bits (126), Expect = 1e-06
Identities = 36/80 (45%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Query: 830 EELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG--TPGGGGPPALEEDLTVININSSD 887
EE A PPP PPP P P Q V TP P EE +
Sbjct: 967 EERAAKVPSTPPPKAAPPP---PALTPDSQTVDSSCKTPEVSFLP--EEATEEAGVRGGA 1021
Query: 888 EEEEEEEEEEEEEEEEEEEE 907
EEEEEEEEEEEEEEEEEE++
Sbjct: 1022 EEEEEEEEEEEEEEEEEEQQ 1041
Score = 49.7 bits (117), Expect = 2e-05
Identities = 29/68 (42%), Positives = 34/68 (50%)
Query: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE 900
P PPP P P L P + + L E+ T EEEEEEEEEEEE
Sbjct: 974 PSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEE 1033
Query: 901 EEEEEEEE 908
EEEEEE++
Sbjct: 1034 EEEEEEQQ 1041
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 9/74 (12%)
Query: 856 PPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEE 915
PPP+ P PPAL D ++ + E EE EE E+ EEEEE
Sbjct: 977 PPPKAAPP-------PPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEE 1029
Query: 916 DEEEYFEEEEEEEE 929
+EEE EEEEEE++
Sbjct: 1030 EEEE--EEEEEEQQ 1041
Score = 43.5 bits (101), Expect = 0.001
Identities = 97/449 (21%), Positives = 126/449 (28%), Gaps = 123/449 (27%)
Query: 696 PSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDET 755
P + PT A HL L PP P P + + + P + PPP PP
Sbjct: 162 PQSNSSRPTCARHLTLGTGDGGPAPP---PAPSSASSSPSPSPSSSSPSPPPPPPPPAPP 218
Query: 756 FGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLP-----PPPPSGATPPP 810
P P F YD +D S PP P P P+G+ P
Sbjct: 219 ---APPAPRFDIYDPFHPTDEAYSP---------------PPAPEQKYDPFEPTGSNPSS 260
Query: 811 IAPTGPPTASPPVPAKEEPEELPAA-----------------------------PGPLPP 841
A T P +EE EE PG P
Sbjct: 261 SAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESP 320
Query: 842 PPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEE 901
P P P P PPQ+ + T G A+ + V+ + E + E
Sbjct: 321 RPDAQPTQPTPAPGTPPQV--DSTRADG---AMRRRVFVVGTEAEACREGKVSVEVVTAG 375
Query: 902 EEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVE 961
+ E EEGE+ + EEE
Sbjct: 376 GAALPPPLLPPGDS--------------------EIEEGEIVQPEEEPRLA--------- 406
Query: 962 DLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGAD 1021
L GG P P A P P+ P PE + L E + G + +
Sbjct: 407 -LSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGE 465
Query: 1022 TAPTLAPEALPS---------------QGEVEREGESPAAGPPPQELVEEEPSAPPTLLE 1066
AP AP A S + + SPA P P + PPT +
Sbjct: 466 PAP--APPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAP-----AAAAGPPTRKK 518
Query: 1067 -----------EETEDGSDKVQPPPETPA 1084
+E S QP P PA
Sbjct: 519 SRRERKRSGEAKEAASSSSGTQPAPPAPA 547
Score = 43.1 bits (100), Expect = 0.001
Identities = 75/329 (22%), Positives = 103/329 (31%), Gaps = 78/329 (23%)
Query: 590 PSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCA---ALTHPRVPPLQPMGPTCP 646
P P P L L+A+ G+ VS + + TCA L P P P+
Sbjct: 139 PIPLPVPSLLPRLRAWRTGKT-----VSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSA 193
Query: 647 TPAPVPPPEAPSPFRAPPFHPPGP---------------MPSVGSMPSAGPMPSAGPMPS 691
+ +P P P + SP PP PP P P P P
Sbjct: 194 SSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEP 253
Query: 692 AGPVPSARPGPPT--------------------------TANHLGLSVPGLV--SVPPRL 723
G PS+ G P+ + + + ++ G+ + +
Sbjct: 254 TGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQD 313
Query: 724 LPGPENHRAGSNEDPILAPSGTPPPTIPPDET-FGGRVPRPAFVHYDKEEASDVEISLES 782
PG E+ R + GTPP D T G + R FV + EA
Sbjct: 314 FPGDESPRPDAQPTQPTPAPGTPPQV---DSTRADGAMRRRVFVVGTEAEAC-------R 363
Query: 783 DSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPP--VPAKEEPEEL-----PAA 835
+ SV +V G A PPP+ P G V +EEP P
Sbjct: 364 EGKVSVEVVTAG---------GAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGG 414
Query: 836 PGPLPPPPPPPPPVPGPVTLPPPQLVPEG 864
P P P P+ PP PEG
Sbjct: 415 RAARPTPAASATPTAQPLPQPPAPRAPEG 443
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 16/87 (18%)
Query: 917 EEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEE-----------ELEEVEDLEF 965
E + EE EE EEEE E EEEEEEE+EEE++
Sbjct: 1003 EVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAG 1062
Query: 966 GTAGGEVEEGAPPP-----PTLPPALP 987
TAG E P PTLPP +P
Sbjct: 1063 STAGDSGAEDGPASRVSQLPTLPPPMP 1089
Score = 40.4 bits (93), Expect = 0.010
Identities = 61/268 (22%), Positives = 84/268 (31%), Gaps = 58/268 (21%)
Query: 590 PSPRCPPPL-------ACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMG 642
P+P PP + A + F +G ++ E +VT P PPL P G
Sbjct: 331 PAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVE-VVTAGGAALP--PPLLPPG 387
Query: 643 PTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPS-ARPG 701
+ + PE F P G +A P P+A P+A P+P P
Sbjct: 388 DSEIEEGEIVQPEEEPRLALSLFRPGG--------RAARPTPAASATPTAQPLPQPPAPR 439
Query: 702 PPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIP-PDETFGGRV 760
P + L L H E + G P P P D +GG
Sbjct: 440 APEGDDFLSL------------------HAESDGEGALQVDLGEPAPAPPAADSRWGGLD 481
Query: 761 PRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTAS 820
R + +E S P P P P+ A P PT +
Sbjct: 482 LRRKILTQRRERYRQRSPS-----------------PAPAPAPAAAAGP---PTRKKSRR 521
Query: 821 PPVPAKEEPEELPAAPGPLPPPPPPPPP 848
+ E E ++ G P PP P P
Sbjct: 522 ERKRSGEAKEAASSSSGTQPAPPAPASP 549
Score = 32.7 bits (73), Expect = 2.0
Identities = 51/234 (21%), Positives = 85/234 (36%), Gaps = 26/234 (11%)
Query: 781 ESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEE----------PE 830
+S ++D LP LPPP P T A + K E E
Sbjct: 1067 DSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQE 1126
Query: 831 ELPAAPGPLPPPPPP------PPPVPGPVTLPP---PQLVPEGTPGGG---GPPALEEDL 878
+ A L PP P PVP + LPP L+P P GG PP
Sbjct: 1127 LIQATNQILSHRKPPSSLGMTPAPVPTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTGLA 1186
Query: 879 TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
+ E + ++ ++ +E EE + + Y+++++ +EE+++ +
Sbjct: 1187 ATSDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKA 1246
Query: 939 EGEL-EEEEEEEDEEEEEELEE--VEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
++ + E + + L V+ + G + G PP P PP P P
Sbjct: 1247 VHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGR-KPGDPPGPPRPPKEPGP 1299
Score = 32.0 bits (71), Expect = 3.4
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 18/97 (18%)
Query: 1016 EERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPT--LLEEETEDGS 1073
EER A T P+A P P A P + V+ P L EE TE+
Sbjct: 967 EERAAKVPSTPPPKAAPP----------PPALTPDSQTVDSSCKTPEVSFLPEEATEEAG 1016
Query: 1074 DKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLA 1110
+ AEEE E E E E +E+E+ A A
Sbjct: 1017 VR------GGAEEEEEEEEEEEEEEEEEEQQPATTTA 1047
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 89.7 bits (221), Expect = 1e-17
Identities = 65/208 (31%), Positives = 88/208 (42%), Gaps = 47/208 (22%)
Query: 746 PPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLP----PP 801
PPP PP G ++PRP V +K + LPP+P PP
Sbjct: 314 PPP--PPPSRGGNQLPRPPIVGGNKGRSGP-------------------LPPVPLGIAPP 352
Query: 802 PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPG----PLPPPPPPPPPVP----GPV 853
PP+ PPP GPP PP + P P PG P+PPPPPPPPP P GP
Sbjct: 353 PPTPRGPPPPGRGGPPPPPPPATGRSGPLP-PPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411
Query: 854 TLP-PPQLVPEG--TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEE------- 903
P PP LVP G PGGG L++ I +N + E + + E
Sbjct: 412 PPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALM 471
Query: 904 ---EEEEEDFEEEEEDEEEYFEEEEEEE 928
++ +E E++ +E+E++E
Sbjct: 472 HVMQKRSRAIHSSDEGEDQAGDEDEDDE 499
Score = 51.2 bits (121), Expect = 5e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPV 695
PP P GP P PPP P+ R+ P PP P G P P P P PS+G
Sbjct: 352 PPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPP--GAGGPPMPPPPPPPPPPPSSGNG 409
Query: 696 PSARPGPPTTANHLGLSVPG 715
P+ P PP GL+ G
Sbjct: 410 PAPPPLPPALVPAGGLAPGG 429
Score = 46.2 bits (108), Expect = 2e-04
Identities = 68/259 (26%), Positives = 91/259 (35%), Gaps = 72/259 (27%)
Query: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709
P+PPP P P R P P+ G+ +GP+P P+ A P P+ R PP
Sbjct: 312 PLPPP--PPPSRGGNQLPRPPIVG-GNKGRSGPLPPV-PLGIAPPPPTPRGPPP------ 361
Query: 710 GLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTP---PPTIPPDETFGGRVPRPAFV 766
PG PP P P R+G P G P PP PP G P P
Sbjct: 362 ----PGRGGPPPP--PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAP--- 412
Query: 767 HYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPP-PPSGATPPPIAPTGPPTASPPVPA 825
PPLPP P+G +AP G A +
Sbjct: 413 -----------------------------PPLPPALVPAGG----LAPGGGRGAL--LDQ 437
Query: 826 KEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININS 885
+ +L PG P L PP EG G + I+S
Sbjct: 438 IRQGIQLNKTPG-----------APESSALQPPPQSSEGLVGALMHVMQKRSRA---IHS 483
Query: 886 SDEEEEEEEEEEEEEEEEE 904
SDE E++ +E+E++E ++
Sbjct: 484 SDEGEDQAGDEDEDDEWDD 502
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 17/94 (18%)
Query: 635 VPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVG-SMPSAGPMPSAG--PMPS 691
+PP+ P+G P P P PP P R P PP P P+ G S P P P AG PMP
Sbjct: 342 LPPV-PLGIAPPPPTPRGPPP---PGRGGP--PPPPPPATGRSGPLPPPPPGAGGPPMPP 395
Query: 692 AGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLP 725
P P P PP++ N P +PP L+P
Sbjct: 396 PPPPP---PPPPSSGNG-----PAPPPLPPALVP 421
Score = 38.1 bits (87), Expect = 0.048
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Query: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHP-PGPMPSVGSMPSAGPMPSAGPMPSAGP 694
PP P P P PPP A P PP P P P PS G+ P+ P+P A +P+ G
Sbjct: 368 PPPPPPATGRSGPLPPPPPGAGGPPMPPP-PPPPPPPPSSGNGPAPPPLPPA-LVPAGGL 425
Query: 695 VPSARPG 701
P G
Sbjct: 426 APGGGRG 432
Score = 36.2 bits (82), Expect = 0.18
Identities = 74/313 (23%), Positives = 101/313 (32%), Gaps = 63/313 (20%)
Query: 821 PPVPAKEEPEELPAAPGPLPPPPPPP------PPVPGPVTL-------PPPQLVPE---G 864
PP PA EE G LPP P P PPV GP++L P + G
Sbjct: 162 PPTPANEERR------GGLPPLPLHPGGDQGGPPV-GPLSLGLATVDIQNPDITSSRYRG 214
Query: 865 TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEE 924
P G PA ++ I+ +D + + + D + D F
Sbjct: 215 LPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRA 274
Query: 925 EEEEEEFEE--------EFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG--------TA 968
E + + +F E++G LE +E +E L G
Sbjct: 275 GISEAQLTDAETSKLIYDFIEDQGGLEAVRQEM--RRQEPLPPPPPPSRGGNQLPRPPIV 332
Query: 969 GGEVEEGAPPPPTLPPALPPPESPPKVQPE-----PEPEPGLLLEVEEPGTEEERGADTA 1023
GG P PP +P + PP P+ P P P P P GA
Sbjct: 333 GGNKGRSGPLPP-VPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGP 391
Query: 1024 PTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAP----PTLLEEETE--------- 1070
P P P G PA P P LV AP LL++ +
Sbjct: 392 P--MPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPG 449
Query: 1071 -DGSDKVQPPPET 1082
S +QPPP++
Sbjct: 450 APESSALQPPPQS 462
Score = 36.2 bits (82), Expect = 0.18
Identities = 19/49 (38%), Positives = 22/49 (44%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAG 681
P PP P P P P PPP + APP PP +P+ G P G
Sbjct: 382 PPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGG 430
Score = 31.6 bits (70), Expect = 4.4
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 10/80 (12%)
Query: 968 AGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGL--------LLEVEEPGTEEER- 1018
AGG PPPP PP+ +PP + P P GL LL+ G + +
Sbjct: 388 AGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKT 447
Query: 1019 -GADTAPTLAPEALPSQGEV 1037
GA + L P S+G V
Sbjct: 448 PGAPESSALQPPPQSSEGLV 467
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 89.4 bits (220), Expect = 2e-17
Identities = 75/199 (37%), Positives = 95/199 (47%), Gaps = 39/199 (19%)
Query: 850 PGPVTLPPPQLVPEGTPGGGG-------PPALEEDLTVININSSD------EEEEEEEEE 896
PGP + Q EG G P EE + V S D E+ EE
Sbjct: 190 PGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESS 249
Query: 897 EEE-----EEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
+++ EEE+EEEEE+ EEEEEDEEE EEEEEE EEEE E EEEEEEE+E
Sbjct: 250 KQKGILSHEEEDEEEEEEEEEEEEDEEE----EEEEEE------EEEEEEEEEEEEEEEE 299
Query: 952 EEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEE 1011
EEEEE E D+ F E+ + P L PES P P+PE +++EV
Sbjct: 300 EEEEEEEAAPDVIF------QEDTSHTSAQKAPELRGPES-----PSPKPEYSVIVEVRS 348
Query: 1012 PGTEEERGADTAPTLAPEA 1030
++E T+ E+
Sbjct: 349 DDDKDEDTHSRKSTVTDES 367
Score = 39.7 bits (91), Expect = 0.016
Identities = 56/252 (22%), Positives = 86/252 (34%), Gaps = 13/252 (5%)
Query: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEE 944
SD E+ E ++ +E E E E E ++E E E + F
Sbjct: 91 SDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSAT 150
Query: 945 EEEEEDEEEEEELEEVEDLEFGTAGGE--VEE----GAPPPPTLPPALPPPESPPKVQPE 998
+ + + L G E VEE A P P + L + +
Sbjct: 151 ASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLL---QEAAEGAAS 207
Query: 999 PEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEP 1058
E E GL ++ E+ E + + L P++L E + ++ EEE
Sbjct: 208 EEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEE 267
Query: 1059 SAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKE---QDDTAAMLADFIDC 1115
EEE E+ ++ + E EEE E E E E + Q+DT+ A
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
Query: 1116 PPDDEKPPPPTE 1127
E P P E
Sbjct: 328 LRGPESPSPKPE 339
Score = 33.5 bits (75), Expect = 1.2
Identities = 44/171 (25%), Positives = 60/171 (35%), Gaps = 22/171 (12%)
Query: 936 EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKV 995
E EG EE E+ + E+ EEV +E T + L P
Sbjct: 200 EAAEGAASEEGEKGLFIQPEDAEEV--VEVTTERSQ-------------DLCPQSLEDAA 244
Query: 996 QPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVE--REGESPAAGPPPQEL 1053
E + G+L EE EEE + E + E E E E +E
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE---EEEEEEEEEEEEEEEEEEEEEEE 301
Query: 1054 VEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
EEE +AP + +E+T S Q PE E + E + E DD
Sbjct: 302 EEEEEAAPDVIFQEDTSHTS--AQKAPELRGPESPSPKPEYSVIVEVRSDD 350
Score = 33.5 bits (75), Expect = 1.2
Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)
Query: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
+EEEEEEEEEE + +E+ ++ E E + E+ E + ++E+
Sbjct: 296 EEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDED 355
Query: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLL 1006
+ + E++D+ G +E+ + P PP Q +
Sbjct: 356 THSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQ-------- 407
Query: 1007 LEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAG 1047
L + EPG + + DT PS+ E +RE + P G
Sbjct: 408 LGLGEPG-KAAKPLDTVRKSYYSKDPSRAE-KREIKCPTPG 446
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 89.4 bits (220), Expect = 2e-17
Identities = 87/283 (30%), Positives = 106/283 (37%), Gaps = 79/283 (27%)
Query: 635 VPPLQPMG----------PTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMP 684
VPPL P P+ P P P PPP P P PP PP P+PS S PSAG
Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPP---PPPPPPPPLPS-QSAPSAG--- 658
Query: 685 SAGPM----------PSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGS 734
SA PM +A A PPT SV + VPP
Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP------------- 705
Query: 735 NEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794
+ ++ P PPP P P P + A + + V + +
Sbjct: 706 --NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIH-----QVQHITQV 758
Query: 795 LPPLPPPPPSGATP-PPIAP----------------------TGPPTASPPV-PAKEEPE 830
PP PPPPP P PP AP PPT +PPV PAK++
Sbjct: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ-- 816
Query: 831 ELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
PA P PP PP PPVP +PPP L + + PP+
Sbjct: 817 --PAFPASYIPPSPPTPPVP----VPPPTLPKQQSFCAKPPPS 853
Score = 87.8 bits (216), Expect = 5e-17
Identities = 80/259 (30%), Positives = 102/259 (39%), Gaps = 41/259 (15%)
Query: 646 PTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPS-AGPMPSAGPVPSARPGPPT 704
PTP P PP AP P +APP P +P+ S + P+ + A P PVP A+ P
Sbjct: 761 PTPPPPPPIPAPLPPQAPP-KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819
Query: 705 TANHLGLSVPGL-VSVPPRLLPGPENHRAGSNEDPILAP---------SGTPPPTIPPDE 754
A+++ S P V VPP LP ++ A P L+P S PPP PP
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSP-LSPVPSVVKQIASQFPPPPTPPAM 878
Query: 755 TFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGAT--PPPIA 812
P PA V A + + S +P P PPPPP + PPP
Sbjct: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSS------IPVPSPDFPPPPPESSLVFPPP-- 930
Query: 813 PTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPP 872
PP P P P PPPPP P P P + +PGG PP
Sbjct: 931 --------PPSPV----------PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP 972
Query: 873 ALEEDLTVININSSDEEEE 891
+ + I +S E E
Sbjct: 973 PTPQRNSSIKSSSGAEHPE 991
Score = 69.7 bits (169), Expect = 1e-11
Identities = 60/213 (28%), Positives = 77/213 (36%), Gaps = 49/213 (23%)
Query: 678 PSAGPMPSAGPMPS-AGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNE 736
P +P P P P +++P PP +PP P P
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPP---------------LPPPPPPPP--------- 636
Query: 737 DPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDK----EEASDVEISL---------ESD 783
P P PPP +P P FV Y + AS +L +S
Sbjct: 637 -PPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695
Query: 784 S-DDSVVIVPEGLPPLPPPPPSGATP---------PPIAPTGPPTASPPVPAKEEPEELP 833
S +++ P G+ P PPPPP TP P AP+ P ++PP P K +
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755
Query: 834 AAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTP 866
P PPPPPP P P P PP LV P
Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAP 788
Score = 67.8 bits (164), Expect = 6e-11
Identities = 70/284 (24%), Positives = 96/284 (33%), Gaps = 36/284 (12%)
Query: 590 PSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPA 649
P+P P P + S + +S S + P PP P P PA
Sbjct: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA 888
Query: 650 PVPPPEAPSPFRAPPFHPPG-PMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANH 708
V P P+ P + P P+PS P P P PVP+ P PP TA+
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS- 947
Query: 709 LGLSVPGLVSVPPRLLPGPENHRA-GSNEDPILAPSGTPPPTIPP-----DETFGGRVPR 762
P P+ + G +P G PP P + G P
Sbjct: 948 ----------------PTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991
Query: 763 PAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPP------SGATPPPIAPTGP 816
P K + D +S + +S E LPP PP SG P + G
Sbjct: 992 P------KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGC 1045
Query: 817 PTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQL 860
+A PV + + + P P PPPP + LPP ++
Sbjct: 1046 VSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEI 1089
Score = 58.9 bits (141), Expect = 3e-08
Identities = 67/231 (29%), Positives = 88/231 (38%), Gaps = 52/231 (22%)
Query: 636 PPLQPMGPTCPTPA-PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGP 694
P QP P+P P PPPE+ F P PP P+P+ P P P+A P P
Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESSLVFPPP---PPSPVPA----PPPPPPPTASPTPD--- 951
Query: 695 VPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGT--PPPTIPP 752
S PG T+ S PG PP P+ + + I + SG P P P
Sbjct: 952 -KSGSPGKKTSKT----SSPGGKKPPPT----PQRNSS------IKSSSGAEHPEPKRPS 996
Query: 753 DETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPP-PPSGATPPPI 811
++ + PA ES S + P PP P SG P +
Sbjct: 997 VDSLVSKFTPPA----------------ESGSPSKETLPPPAAPPKPGKLNLSGVNLPGV 1040
Query: 812 APTGPPTASPPV---PAKEEPEELPAAPGPLPPPPPPPP---PVPGPVTLP 856
G +A PV K+ E P+ P PPPPP P+P P+ +P
Sbjct: 1041 LQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP-PIEIP 1090
Score = 53.1 bits (126), Expect = 1e-06
Identities = 29/71 (40%), Positives = 33/71 (46%), Gaps = 17/71 (23%)
Query: 803 PSGATPPPIAP----TGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPP 858
P + PP++P P TAS P P PLPPPPPPPPP P P PPP
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSP-------------PLPPPPPPPPPPPPPPPPPPP 647
Query: 859 QLVPEGTPGGG 869
L + P G
Sbjct: 648 PLPSQSAPSAG 658
Score = 47.4 bits (111), Expect = 8e-05
Identities = 25/87 (28%), Positives = 33/87 (37%), Gaps = 15/87 (17%)
Query: 802 PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLV 861
PP P + P SPP+P PPPPPPPPP P P PPP
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLP---------------PPPPPPPPPPPPPPPPPPPLPS 651
Query: 862 PEGTPGGGGPPALEEDLTVININSSDE 888
G P + T+ + ++ +
Sbjct: 652 QSAPSAGSAAPMFVKYSTITRLQNASQ 678
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/187 (21%), Positives = 67/187 (35%), Gaps = 37/187 (19%)
Query: 972 VEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEAL 1031
+ + APP P PP +P P PP+ P+P L+ + P + + P
Sbjct: 755 ITQVAPPTPPPPPPIPAP-LPPQAPPKP------LVTIPAPTSTKTVAPVVTQAAPPTPT 807
Query: 1032 PSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEET-----------------EDGSD 1074
P +++ PA+ PP P PPTL ++++ + +
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867
Query: 1075 KVQPPPETPAEEEM-----------ETETEAEALQEKEQDDTAAMLADFIDCPPDDEK-- 1121
+ PPP PA E ++ +A + + DF PP+
Sbjct: 868 QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF 927
Query: 1122 PPPPTEP 1128
PPPP P
Sbjct: 928 PPPPPSP 934
Score = 41.6 bits (96), Expect = 0.004
Identities = 38/164 (23%), Positives = 61/164 (37%), Gaps = 11/164 (6%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPS-QG 1035
PPPP PPP P P P P P ++ G+ ++ + T+ + P+ Q
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR 977
Query: 1036 EVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP--PETPAEEEMETETE 1093
+ S A P P+ + + T E + + PP P P + +
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037
Query: 1094 AEALQEKEQDDTAAMLA--------DFIDCPPDDEKPPPPTEPD 1129
LQ+ A +L+ +F P D + PPPP E +
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETE 1081
Score = 40.8 bits (94), Expect = 0.007
Identities = 40/152 (26%), Positives = 52/152 (34%), Gaps = 32/152 (21%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
P PP PP PPP PP P P P P + A +A + AP +
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLP-------------SQSAPSAGSAAPMFVKYSTI 670
Query: 1037 VEREGESPAAG---PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETE 1093
+ S +G PP V + S P +L + V PPP P T
Sbjct: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP----NGVVPPPPPPP-----PPPTP 721
Query: 1094 AEALQEKEQDDTAAMLADFIDCPPDDEKPPPP 1125
A+ + + A L F PPPP
Sbjct: 722 GSAMAQLKPAPCAPSLPQF-------SAPPPP 746
Score = 38.9 bits (89), Expect = 0.028
Identities = 20/57 (35%), Positives = 23/57 (40%)
Query: 817 PTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
P S P +P+ + P PP PPPP P P PPP P P P A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
Score = 34.3 bits (77), Expect = 0.69
Identities = 39/176 (22%), Positives = 57/176 (32%), Gaps = 48/176 (27%)
Query: 976 APPPPTLPPALPPPE-------------SPPKVQPEPEPEPGLLLEVEEPGTEEERGADT 1022
APPPP P A P P+ SP +P P P+ ++ E +
Sbjct: 937 APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS 996
Query: 1023 APTLAPEALP--SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEE---------TED 1071
+L + P G +E P A PP + P +L++ +
Sbjct: 997 VDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGR 1056
Query: 1072 GSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTE 1127
G D V P P++ +DF PP+ E P PP E
Sbjct: 1057 GKDSVVEFPSPPSD------------------------SDFPPPPPETELPLPPIE 1088
Score = 33.5 bits (75), Expect = 1.2
Identities = 41/160 (25%), Positives = 51/160 (31%), Gaps = 35/160 (21%)
Query: 975 GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP-- 1032
G PPP P PPP +P + +P P AP+L + P
Sbjct: 707 GVVPPP---PPPPPPPTPGSAMAQLKPAP------------------CAPSLPQFSAPPP 745
Query: 1033 ----SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM 1088
Q + + P PPP P APP L S K P T A
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805
Query: 1089 ETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
T A ++ A A +I PP PP P P
Sbjct: 806 PTPPVPPAKKQ------PAFPASYI--PPSPPTPPVPVPP 837
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 88.2 bits (217), Expect = 4e-17
Identities = 94/326 (28%), Positives = 136/326 (41%), Gaps = 48/326 (14%)
Query: 809 PPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGT--- 865
PP P P V +E+ E P P G LP + E T
Sbjct: 1276 PPETPMEP---DEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAP 1332
Query: 866 --PGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE 923
P E+DL I +EEEEEEEEEEEEEEEE EEEE E+D + +
Sbjct: 1333 VSPNTSPGEKPEDDL----IKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQ 1388
Query: 924 EEEEEEEFEEEFEEEEGELEEEEEEEDEE----EEEELEEVEDLEFGTAGGEVEEGAPPP 979
E+EE E E+ + + EEEEEEDEE E+ + ++ +D +A EVE+ P
Sbjct: 1389 EKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESA--EVEKEELPR 1446
Query: 980 PTLPPALPPPESPPKVQPEP-EPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVE 1038
+ L E+ + +P P +L++ G D + E G+ E
Sbjct: 1447 ESFKEVLENQETFLDLNVQPGHSNPEVLMDC---------GVDLTASCNSEPKELAGDPE 1497
Query: 1039 REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETET----EA 1094
ES PPP E +++ ++ E ++G+ PA E+++ET ++
Sbjct: 1498 AVPESDEE-PPPGEQAQKQDQKNSKEVDTEFKEGN---------PATMEIDSETVQAVQS 1547
Query: 1095 EALQEKEQDDTAAMLADFIDCPPDDE 1120
+ EQDDT F DC E
Sbjct: 1548 LTQESSEQDDT------FQDCAETQE 1567
Score = 69.3 bits (168), Expect = 2e-11
Identities = 70/259 (27%), Positives = 107/259 (41%), Gaps = 42/259 (16%)
Query: 872 PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931
P E ++ ++ EEEEEEE+EEEEEEEEEEEED EEEEE+E EEEEEE +
Sbjct: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEE----EEEEEENIQS 1108
Query: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPES 991
+ + + + +++ + + + E T P ++
Sbjct: 1109 SPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISE------TTEVLNEPFDN 1162
Query: 992 PPKVQPEPEPEPGLLLEVEEPG------------------TEEERGADTAPTLAPEALPS 1033
+ +P P+ EP +EVEE G TEEE G D A P
Sbjct: 1163 SDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDN--HCFKNADPC 1220
Query: 1034 QGEVEREGESPAAG----PPPQELVEEEPSAPPTLLEEETEDGSDK------VQPPPETP 1083
+ + + + G P P + + P L + ++ K + PPETP
Sbjct: 1221 RNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETP 1280
Query: 1084 AE--EEMETETEAEALQEK 1100
E E++ E + E + K
Sbjct: 1281 MEPDEQVTVEEQKETSEGK 1299
Score = 62.0 bits (149), Expect = 3e-09
Identities = 89/357 (24%), Positives = 128/357 (35%), Gaps = 100/357 (28%)
Query: 862 PEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE---- 917
PE P G L E + +EE+EEEEEEEEEEEE+EEEEE+ EEEEE+E
Sbjct: 1049 PESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108
Query: 918 ------------------------------------------------EEYFEEEEEE-- 927
E F+ +EE
Sbjct: 1109 SPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERP 1168
Query: 928 --------EEEFEEE---------FEEEEGELEEEEEEEDEEEE--EELEEVEDLEFGTA 968
E E EE+ F+ + G+ + EEEE ++ + + +
Sbjct: 1169 MPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRN-NMNDD 1227
Query: 969 GGEVEEGA---PPPPTLPPALP--PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTA 1023
++EG+ P P P K + E + G L + P E D
Sbjct: 1228 SSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTP-PETPMEPDEQ 1286
Query: 1024 PTLAPEALPSQGE-------VEREGESPAAGPPPQELVEEE----PSAPPTLLEEETEDG 1072
T+ + S+G+ +E E + PQE E P +P T E+ ED
Sbjct: 1287 VTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPED- 1345
Query: 1073 SDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPD 1129
D ++P E EEE E E E E +E+E ++ PD K EP+
Sbjct: 1346 -DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGN-------VEKDPDGAKSQEKEEPE 1394
Score = 53.5 bits (127), Expect = 1e-06
Identities = 66/235 (28%), Positives = 91/235 (38%), Gaps = 43/235 (18%)
Query: 878 LTVININSSDEEEEEEEEEEEEEEE----EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933
+ + N S+EE E E+E E E+ E+EE+E + + + + +
Sbjct: 990 ILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSP 1049
Query: 934 EFEEEEGEL-----------EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL 982
E GE EEEEEEEDEEEEEE EE E+ E E EE +
Sbjct: 1050 ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109
Query: 983 PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE 1042
PP L P+S + P + ++ G + R + T E + EV E
Sbjct: 1110 PPRLTKPQSVAIKRKRP------FVLKKKRGRKRRRINSSVTT---ETISETTEVLNE-- 1158
Query: 1043 SPAAGPPPQELVEEE---PSAPPTLLEEETEDGSDKV-------QPPPETPAEEE 1087
P + +EE P PT E EDG V QP + EEE
Sbjct: 1159 -------PFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEE 1206
Score = 52.0 bits (123), Expect = 3e-06
Identities = 86/349 (24%), Positives = 126/349 (36%), Gaps = 111/349 (31%)
Query: 887 DEEEEEEEEEEEEEEEEEEEE--------------------------------------- 907
+EEEEE+EEEEEEEEEEEEEE
Sbjct: 1084 EEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSS 1143
Query: 908 ---EDFEEEEEDEEEYFEEEEEE----------EEEFEEE---------FEEEEGELEEE 945
E E E E F+ +EE E E EE+ F+ + G+ +
Sbjct: 1144 VTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQT 1203
Query: 946 EEEEDEEEE--EELEEVEDLEFGTAGGEVEEGA---PPPPTLPPALPP--PESPPKVQPE 998
EEEE ++ + + + ++EG+ P P P K +
Sbjct: 1204 EEEEGKDNHCFKNADPCRN-NMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQN 1262
Query: 999 PEPEPGLLL----------EVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGP 1048
E + G L E +E T EE+ + +P + + EV+ GE+
Sbjct: 1263 KERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALL--- 1319
Query: 1049 PPQELVEEE---PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEA--------- 1096
P +E EE P +P T E+ ED D ++P E EEE E E E E
Sbjct: 1320 PQEENRREETCAPVSPNTSPGEKPED--DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGN 1377
Query: 1097 ---------LQEKEQ------DDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
QEKE+ + +A L D + +DE+P + D+
Sbjct: 1378 VEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDA 1426
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/57 (31%), Positives = 24/57 (42%), Gaps = 6/57 (10%)
Query: 804 SGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQL 860
S + P++ TG V + P +P P PPP P P+ LPPP L
Sbjct: 1846 SASLSTPLSNTGL------VQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLL 1896
Score = 30.4 bits (67), Expect = 9.9
Identities = 38/174 (21%), Positives = 65/174 (37%), Gaps = 20/174 (11%)
Query: 957 LEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEE 1016
L +E L+ + E++ P P L + + + E E E L+E +E
Sbjct: 965 LSHMEKLKTCSRANELD---PDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKE 1021
Query: 1017 ERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKV 1076
E+ L+ A Q + + ++ P V E L +E +E+ ++
Sbjct: 1022 EQ-----EILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEE 1076
Query: 1077 QPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
E EEE E E E E +E+E+++ PP T+P S
Sbjct: 1077 DEEEEEEEEEEEEDEEEEEEEEEEEEEENI------------QSSPPRLTKPQS 1118
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 88.2 bits (217), Expect = 4e-17
Identities = 85/264 (32%), Positives = 114/264 (43%), Gaps = 21/264 (7%)
Query: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE--EEEEEEEEFEEEFEEEEGELE 943
SD E + + E EE +E E E + E + + E + E E EEE +E E E +E EGE
Sbjct: 2020 SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAH 2079
Query: 944 EEEEEED--EEEEEELEEVEDLEFGTAGGEVE--EGAPPPPTLPPALPPPE--SPPKVQP 997
E E+ D E E E E E +E A GE + EG P T A P E P+ +
Sbjct: 2080 PESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEG 2139
Query: 998 EPEPE-PGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQ--ELV 1054
E +PE G+ + E + E A EA P VE A P + E
Sbjct: 2140 EAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAP 2199
Query: 1055 EEEPSAPPTLLEEETEDGSDKVQPPP---ETP-AEEEMETETEAEALQEKEQD------D 1104
E E A P L E + ++ QP P ETP AE E + E+E E EK+ D
Sbjct: 2200 EAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGD 2259
Query: 1105 TAAMLADFIDCPPDDEKPPPPTEP 1128
+ A P +++P PP P
Sbjct: 2260 GQSEEASESSSPVPEDRPTPPPSP 2283
Score = 87.4 bits (215), Expect = 7e-17
Identities = 97/375 (25%), Positives = 144/375 (38%), Gaps = 20/375 (5%)
Query: 772 EASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEE 831
EA + E + +S+D V PE + P GA P P + E E+
Sbjct: 1875 EAPEAEGEAQPESED--VETPEAEWEVQPES-EGAEAPEAEKEAQPETESVEALETEGED 1931
Query: 832 LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVP------EGTPGGGGPPALEEDLTVININS 885
P + G T P +++ E P ALE ++
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945
+ E E+ E E E E +E EE+ + E + E + E EE +E E E ++ EG+ + E
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPE 2051
Query: 946 EEE-EDEEEEEELEEVEDLEFGTAGGEVE-EGAPPPPTLPPALPPPESPPKVQPEPEPEP 1003
+ E E EEE +E E E A GE E PES PE E E
Sbjct: 2052 SDGVEAPEAEEEAQEAEG-EVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110
Query: 1004 GLLLEVEEPGTEEERGADT----APTLAPEALPSQGEVEREGESPAAGPPPQ--ELVEEE 1057
+E P TE E ++ AP EA P VE + A P + E E E
Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170
Query: 1058 PSAPPTLLEEETEDGSDKVQPPPE--TPAEEEMETETEAEALQEKEQDDTAAMLADFIDC 1115
A P L E + + QP E E E E + E E ++ E ++ A + ++
Sbjct: 2171 EEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVET 2230
Query: 1116 PPDDEKPPPPTEPDS 1130
P + + P +E ++
Sbjct: 2231 PEAEGEAQPESEGET 2245
Score = 83.6 bits (205), Expect = 1e-15
Identities = 78/290 (26%), Positives = 112/290 (38%), Gaps = 10/290 (3%)
Query: 846 PPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEE 905
P G + P+ E P G A E + + E E+ E E E E +
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885
Query: 906 EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEF 965
E ED E E + E E E E E E+E + E +E E E ++E E E E ++ E
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE- 1944
Query: 966 GTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT 1025
+ EG P + + E+ + QPE E L +EVE E E ++
Sbjct: 1945 --EAAQEAEGQTQPES--EVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDV 2000
Query: 1026 LAPEALPSQGEVEREGESPAAGPPPQELVE----EEPSAPPTLLEEETEDGSDKVQPPPE 1081
APEA E E E + + G Q E +E E + + SD V+ P
Sbjct: 2001 EAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEA 2060
Query: 1082 TPAEEEMETET-EAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
+E E E EAE E +D A A+ P + P E ++
Sbjct: 2061 EEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110
Score = 72.4 bits (176), Expect = 2e-12
Identities = 71/261 (27%), Positives = 113/261 (43%), Gaps = 44/261 (16%)
Query: 885 SSDEEEEEEEEE------EEEEEEEEEEEEDFEEEEEDEE-EYFEEE--EEEEEEFEEEF 935
+ DE E + EE+ E+ E +EE EE +E E E +EE + EE + EE
Sbjct: 1272 NEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGL 1331
Query: 936 EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKV 995
+EE +LEE +E E E ++EE ++E++E G EEG
Sbjct: 1332 QEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGV----------------QLE 1375
Query: 996 QPEPEPEPGLLLEVEEPGTEEE--------RGADTAPTLAPEALPSQG----EVEREGES 1043
+ + PE GL E E G +EE G + + +P+ SQ + E G +
Sbjct: 1376 EVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRA 1435
Query: 1044 PAAGPPPQELVEEEPSAPPTLLEEETEDGSDK-----VQPPPETPAEEEM--ETETEAEA 1096
A+ P EEP+ PP+ L E S++ ++P E P M + T+A+
Sbjct: 1436 SASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQP 1495
Query: 1097 LQEKEQDDTAAMLADFIDCPP 1117
Q + ++ + +DC P
Sbjct: 1496 TQGAAERSSSVACSAALDCDP 1516
Score = 67.8 bits (164), Expect = 6e-11
Identities = 66/257 (25%), Positives = 100/257 (38%), Gaps = 27/257 (10%)
Query: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
D + E +++ + + E E E + E E E E E E + +E EGE + E
Sbjct: 1812 DNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPES 1871
Query: 947 EEEDEEEEE-----ELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP 1001
E+ + E E E E+VE E EGA P A P ES ++ E E
Sbjct: 1872 EDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED 1931
Query: 1002 EP---GLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEP 1058
EP G + E +E G + E+ ++ E + E E A E E E
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 1059 SAPPTL--------------LEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
A P EEE + SD V+ P++ EE E E E + + Q +
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPE 2051
Query: 1105 TAAMLADFIDCPPDDEK 1121
+D ++ P +E+
Sbjct: 2052 -----SDGVEAPEAEEE 2063
Score = 67.0 bits (162), Expect = 1e-10
Identities = 65/237 (27%), Positives = 100/237 (42%), Gaps = 25/237 (10%)
Query: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFE-------EEEEDEEEYFEEEEEEEEEFEEEF 935
+ +++E E E E + E++ + +++ + + E E E E E +
Sbjct: 1787 LGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQP 1846
Query: 936 EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKV 995
E E E E E + E E E E ED+E A GE + + T PE+ +V
Sbjct: 1847 ESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVET-------PEAEWEV 1899
Query: 996 QPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVE 1055
QPE E E P E+E +T + EAL ++GE E E E A + E
Sbjct: 1900 QPESE-------GAEAPEAEKEAQPETE---SVEALETEGEDEPESEGAEAQEAEEAAQE 1949
Query: 1056 EEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETET-EAEALQEKEQDDTAAMLAD 1111
E P E+++ ++ QP E E+E ET EAE + E +D A A+
Sbjct: 1950 AEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAE 2006
Score = 62.8 bits (151), Expect = 2e-09
Identities = 70/249 (28%), Positives = 95/249 (38%), Gaps = 23/249 (9%)
Query: 820 SPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQ--LVPEGTPGGGGPPALEED 877
S V A E EE A G + P V + PE + G P A E
Sbjct: 2052 SDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPE-SEGVEAPEAEGEA 2110
Query: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937
I + + E E + E E E E E E E E + ++ E + E E E + E
Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170
Query: 938 EEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE---EGAPPPPTLPPALPPPESPPK 994
EE + E E E E E E E E +E A GE + EG P A P PE
Sbjct: 2171 EEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVET 2230
Query: 995 VQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELV 1054
+ E E +P E E E++G +P+ G+ E ES + P
Sbjct: 2231 PEAEGEAQP----ESEGETQGEKKG-------SPQVSLGDGQSEEASESSSPVP------ 2273
Query: 1055 EEEPSAPPT 1063
E+ P+ PP+
Sbjct: 2274 EDRPTPPPS 2282
Score = 50.4 bits (119), Expect = 9e-06
Identities = 49/169 (28%), Positives = 65/169 (38%), Gaps = 21/169 (12%)
Query: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
+ + D E E + E E E +E EEE E E + E E + E E E E E +
Sbjct: 2148 VEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQP 2207
Query: 943 EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPE 1002
E E E E EEE E E +E A GE + PES + Q E +
Sbjct: 2208 ELEGVEAPEAEEEAQPEPEGVETPEAEGEAQ---------------PESEGETQGEKKGS 2252
Query: 1003 PGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQ 1051
P + L + E + P P PS G G++P P Q
Sbjct: 2253 PQVSLG-DGQSEEASESSSPVPEDRPTPPPSPG-----GDTPHQRPGSQ 2295
Score = 45.4 bits (106), Expect = 3e-04
Identities = 48/197 (24%), Positives = 69/197 (35%), Gaps = 8/197 (4%)
Query: 813 PTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPP 872
P +P + + E AP P + P Q EG
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEG 2155
Query: 873 ALEEDLTVININSSDEEEEEE---EEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929
+ + I ++EE + E E E E E + E E E E + E E E E
Sbjct: 2156 EAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAP 2215
Query: 930 EFEEEFEEEEGELE----EEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPA 985
E EEE + E +E E E + + E E + E+ + G+ EE + +P
Sbjct: 2216 EAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPED 2275
Query: 986 LP-PPESPPKVQPEPEP 1001
P PP SP P P
Sbjct: 2276 RPTPPPSPGGDTPHQRP 2292
Score = 30.8 bits (68), Expect = 7.6
Identities = 34/117 (29%), Positives = 40/117 (34%), Gaps = 17/117 (14%)
Query: 642 GPTCPTPA---PVPPPEAPSPFRAPPFHP-----PGPMPSVGSMPSAGPMPSAGPMPSAG 693
G CPTP P P + S H PG P G+ GP PS GP A
Sbjct: 850 GRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTR-QPGPTPSPGPNSGAS 908
Query: 694 PVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTI 750
SA G A GLS + R GP+ S P P +P +
Sbjct: 909 RRSSASQG----AGSRGLSEEKTL----RSGGGPQGQEEASGVSPSSLPRSSPEAVV 957
Score = 30.4 bits (67), Expect = 9.9
Identities = 18/64 (28%), Positives = 24/64 (37%), Gaps = 8/64 (12%)
Query: 815 GPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
GP T + ++ P P P P PP P PG P+ TP GP
Sbjct: 254 GPKTKPSVIHSRSPPGSTPRLPERPGPSNPPVGPAPG--------RHPQDTPAQSGPLVA 305
Query: 875 EEDL 878
+D+
Sbjct: 306 GDDM 309
>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
Length = 1812
Score = 87.8 bits (216), Expect = 5e-17
Identities = 67/223 (30%), Positives = 96/223 (43%), Gaps = 26/223 (11%)
Query: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTA----------SPPVPAKEEPEELP 833
S D V+ PP PPPPP P P P A SPP P P
Sbjct: 127 SVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPR--- 183
Query: 834 AAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG-------TPGGGGPPALEEDLTVININSS 886
PGP PP PVP PV+ + P +P P + +
Sbjct: 184 TPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQ------YSDE 237
Query: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
E EEE++EE EE+E++ + EE+ +E+E+D EEEEE+ EEE EE+E ++
Sbjct: 238 GEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDG 297
Query: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
E+ +E+ + ++E F +VE A ++PP P
Sbjct: 298 YEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDP 340
Score = 51.2 bits (121), Expect = 5e-06
Identities = 43/141 (30%), Positives = 59/141 (41%), Gaps = 10/141 (7%)
Query: 968 AGGEVEE---GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAP 1024
A GE E+ G+PP P PP PP E +P P + G +EE
Sbjct: 162 ADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVP-----LPVSGDKEEDAPHRED 216
Query: 1025 TLAPEALPSQGEVEREGESPAAGPPPQELVEE-EPSAPPTLLEEETEDGSDKVQPPPETP 1083
P + P + V +EG+ G +E EE E +EEE ++ D + P
Sbjct: 217 YFEPIS-PDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIP 275
Query: 1084 AEEEMETETEAEALQEKEQDD 1104
EEE + E E E +E E DD
Sbjct: 276 EEEEEDEEEEGEEDEEGEGDD 296
Score = 43.9 bits (102), Expect = 9e-04
Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 23/128 (17%)
Query: 987 PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046
PPP PP P P+P+P L + E+E + +P P P G
Sbjct: 140 PPPPPPP---PPPQPQPSLKRNPKHADGEKEDQFNGSP---PRPQP-------RGPRTPP 186
Query: 1047 GPPPQELVEEEPSAPPTLLEEE-----TEDGSDKVQP-----PPETPAEEEMETETEAEA 1096
GPPP + E++P P ++E ED + + P P E +E E E E +
Sbjct: 187 GPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE 246
Query: 1097 LQEKEQDD 1104
E+++DD
Sbjct: 247 EGEEDEDD 254
Score = 32.0 bits (71), Expect = 3.4
Identities = 36/144 (25%), Positives = 49/144 (34%), Gaps = 21/144 (14%)
Query: 646 PTPAPVPPPEAPSP-FRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPT 704
P P P PPP P P + P H G + P P P PGPP
Sbjct: 140 PPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRG---------PRTPPGPPP 190
Query: 705 TANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFG--GRVPR 762
+ VP VS G + A ED P ++P + + G V
Sbjct: 191 PDDDEDDPVPLPVS-------GDKEEDAPHRED-YFEPISPDRNSVPQEGQYSDEGEVEE 242
Query: 763 PAFVHYDKEEASDVEISLESDSDD 786
+E+ DV++ E D D+
Sbjct: 243 EQ-QEEGEEDEDDVDVEEEEDEDE 265
>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
Length = 1147
Score = 87.8 bits (216), Expect = 5e-17
Identities = 67/223 (30%), Positives = 96/223 (43%), Gaps = 26/223 (11%)
Query: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTA----------SPPVPAKEEPEELP 833
S D V+ PP PPPPP P P P A SPP P P
Sbjct: 127 SVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPR--- 183
Query: 834 AAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG-------TPGGGGPPALEEDLTVININSS 886
PGP PP PVP PV+ + P +P P + +
Sbjct: 184 TPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQ------YSDE 237
Query: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
E EEE++EE EE+E++ + EE+ +E+E+D EEEEE+ EEE EE+E ++
Sbjct: 238 GEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDG 297
Query: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
E+ +E+ + ++E F +VE A ++PP P
Sbjct: 298 YEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDP 340
Score = 51.2 bits (121), Expect = 5e-06
Identities = 43/141 (30%), Positives = 59/141 (41%), Gaps = 10/141 (7%)
Query: 968 AGGEVEE---GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAP 1024
A GE E+ G+PP P PP PP E +P P + G +EE
Sbjct: 162 ADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVP-----LPVSGDKEEDAPHRED 216
Query: 1025 TLAPEALPSQGEVEREGESPAAGPPPQELVEE-EPSAPPTLLEEETEDGSDKVQPPPETP 1083
P + P + V +EG+ G +E EE E +EEE ++ D + P
Sbjct: 217 YFEPIS-PDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIP 275
Query: 1084 AEEEMETETEAEALQEKEQDD 1104
EEE + E E E +E E DD
Sbjct: 276 EEEEEDEEEEGEEDEEGEGDD 296
Score = 43.9 bits (102), Expect = 9e-04
Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 23/128 (17%)
Query: 987 PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA 1046
PPP PP P P+P+P L + E+E + +P P P G
Sbjct: 140 PPPPPPP---PPPQPQPSLKRNPKHADGEKEDQFNGSP---PRPQP-------RGPRTPP 186
Query: 1047 GPPPQELVEEEPSAPPTLLEEE-----TEDGSDKVQP-----PPETPAEEEMETETEAEA 1096
GPPP + E++P P ++E ED + + P P E +E E E E +
Sbjct: 187 GPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE 246
Query: 1097 LQEKEQDD 1104
E+++DD
Sbjct: 247 EGEEDEDD 254
Score = 32.0 bits (71), Expect = 3.4
Identities = 36/144 (25%), Positives = 49/144 (34%), Gaps = 21/144 (14%)
Query: 646 PTPAPVPPPEAPSP-FRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPT 704
P P P PPP P P + P H G + P P P PGPP
Sbjct: 140 PPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRG---------PRTPPGPPP 190
Query: 705 TANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFG--GRVPR 762
+ VP VS G + A ED P ++P + + G V
Sbjct: 191 PDDDEDDPVPLPVS-------GDKEEDAPHRED-YFEPISPDRNSVPQEGQYSDEGEVEE 242
Query: 763 PAFVHYDKEEASDVEISLESDSDD 786
+E+ DV++ E D D+
Sbjct: 243 EQ-QEEGEEDEDDVDVEEEEDEDE 265
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 87.8 bits (216), Expect = 5e-17
Identities = 80/260 (30%), Positives = 100/260 (38%), Gaps = 69/260 (26%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPP-EAPSPFRAPPFHPPGPMPSVGSMP-SAGPMPSAGPMP 690
P VP P P P P P+PPP + SP + P PPGP+ + G++P A P+P A P P
Sbjct: 169 PNVPAPPPPTPP-PPPPPLPPPLPSSSPIKTPLVSPPGPL-TKGNLPVVAPPVPCAPPPP 226
Query: 691 SAGPVPSARPGPPTTA------------NHLGLSVPGLVSVPPRLLPGPENHRAGSNEDP 738
P P+ P PP + HL P L +PP PG + A +D
Sbjct: 227 PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDA 286
Query: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798
P+ PPP +PP + R PA PPL
Sbjct: 287 QEPPA--PPPPLPPYASCSPRASLPA-------------------------------PPL 313
Query: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPP 858
P S TPPP+ P P +PP A + LP PP PP + P
Sbjct: 314 PGVNSSSETPPPLPPKSPSFQAPPQKAGAQ---------ALPAPPAPPG------SQPFL 358
Query: 859 QLVPEGTPGGGG-----PPA 873
Q G PG GG PPA
Sbjct: 359 QKKRHGRPGAGGGKLNPPPA 378
Score = 77.4 bits (189), Expect = 7e-14
Identities = 79/269 (29%), Positives = 99/269 (36%), Gaps = 54/269 (20%)
Query: 640 PMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMP---SVGSMPSAGPMPSAGPMP------ 690
P+ P P P P PPP P APP PP P S+ A P + +
Sbjct: 2 PVPPPPPPPLPPPPP----PLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
Query: 691 -----------SAGPVPSARPGPPT---TANHLGLSVPGLVSVP-----PRLLPGPENHR 731
SA + S++ +AN G S P + P L P +
Sbjct: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
Query: 732 AGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHY-DKEEASDVEISLESDSDDSVVI 790
AG P P P++T G + PA + EA + +
Sbjct: 118 AGGKTGQ--GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN----- 170
Query: 791 VPEGLPPLPPPPPSGATPPPIAPTGP---PTASPPVPAKEEPEELPAAPGPLPPPPPPPP 847
VP PP PPPPP PPP+ + P P SPP P + + A P P PPPPPPP
Sbjct: 171 VPAPPPPTPPPPPP-PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP 229
Query: 848 PVPGPVTLPP----------PQLVPEGTP 866
P P P LPP PQL P P
Sbjct: 230 PPPTPPPLPPASVLSDKAVKPQLAPLHLP 258
Score = 68.6 bits (166), Expect = 3e-11
Identities = 76/261 (29%), Positives = 94/261 (36%), Gaps = 77/261 (29%)
Query: 633 PRVPPLQPMGPTCPTPAPV--PPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMP 690
PR+P GP P +P EA R P P P P + P P P P+P
Sbjct: 133 PRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPP-PLPPPLP 191
Query: 691 SAGPV--PSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPP 748
S+ P+ P P P T +L + P + PP P PPP
Sbjct: 192 SSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP-------------------PPPPPPPP 232
Query: 749 TIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATP 808
T PP +P PA V DK + P LPP+PPP P
Sbjct: 233 TPPP-------LP-PASVLSDKAVKPQ--------------LAPLHLPPIPPPLPL---- 266
Query: 809 PPIAPTGPP--TASPPVPAKEEPEELPAAPGPLPPPPPPP------------PPVPG--- 851
+ P G P A P PA++ E P PPPP PP PP+PG
Sbjct: 267 --LPPCGYPGLKAEPASPAQDAQEP------PAPPPPLPPYASCSPRASLPAPPLPGVNS 318
Query: 852 PVTLPPPQLVPEGTPGGGGPP 872
PPP +P +P PP
Sbjct: 319 SSETPPP--LPPKSPSFQAPP 337
Score = 62.4 bits (150), Expect = 2e-09
Identities = 71/266 (26%), Positives = 92/266 (34%), Gaps = 54/266 (20%)
Query: 646 PTPAPVPPPEAPSPFRAPPFHPPGPMP---SVGSMPSAGPMPSAGPMP------------ 690
P P P+PPP P P APP PP P S+ A P + +
Sbjct: 6 PPPPPLPPP--PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63
Query: 691 -----SAGPVPSARPGPPT---TANHLGLSVPGLVSVP-----PRLLPGPENHRAGSNED 737
SA + S++ +AN G S P + P L P + AG
Sbjct: 64 QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTG 123
Query: 738 PILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPP 797
P P P++T G + PA + + VP PP
Sbjct: 124 Q--GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN----VPAPPPP 177
Query: 798 LPPPPPSGATPPPIAPTGP---PTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVT 854
PPPPP PPP+ + P P SPP P + + A P P PPPPPPP
Sbjct: 178 TPPPPPP-PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP------- 229
Query: 855 LPPPQLVPEGTPGGGGPPALEEDLTV 880
P TP P ++ D V
Sbjct: 230 -------PPPTPPPLPPASVLSDKAV 248
Score = 58.9 bits (141), Expect = 3e-08
Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 44/247 (17%)
Query: 646 PTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTT 705
P P P PPP P P PP P P P PSA P+ + S R P
Sbjct: 2 PVPPPPPPPLPPPP---PPLGAPPPPP-----------PSAPPVST--DTSSLRRADPKG 45
Query: 706 ANHL------GLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPS--GTPPPTIPPDETFG 757
+ L G + + + R P E+ + + E A + + PPT+ + F
Sbjct: 46 RSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTL--GDLFA 103
Query: 758 GRVP--RPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTG 815
G P RPA DV S P LP SG PP +P
Sbjct: 104 GGFPVLRPA-------GQRDVAGGKTGQGPGSRAPSPR----LPNKTISGPLIPPASPRL 152
Query: 816 PPTASPPVPAKEEPEELPAAPGPLPP-PPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
T+ A+ P P P P PP PPPPPPP+P P+ P P +P G P
Sbjct: 153 GNTSEAHGAARTAPPR-PNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPG---PLT 208
Query: 875 EEDLTVI 881
+ +L V+
Sbjct: 209 KGNLPVV 215
Score = 55.1 bits (131), Expect = 4e-07
Identities = 60/201 (29%), Positives = 71/201 (35%), Gaps = 25/201 (12%)
Query: 680 AGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPI 739
AG AG GP +R P N +S P + PRL E H A P
Sbjct: 112 AGQRDVAGGKTGQGP--GSRAPSPRLPNKT-ISGPLIPPASPRLGNTSEAHGAARTAPPR 168
Query: 740 LAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDD------SVVIVPE 793
PPPT PP +P P +S ++ L S VV P
Sbjct: 169 PNVPAPPPPTPPPPPP---PLPPPL------PSSSPIKTPLVSPPGPLTKGNLPVVAPPV 219
Query: 794 GLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPP--PPPPVPG 851
P PPPPP TPPP+ P AS +P+ P P+PPP P PP PG
Sbjct: 220 PCAPPPPPPPPPPTPPPLPP-----ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
Query: 852 PVTLPPPQLVPEGTPGGGGPP 872
P P PP
Sbjct: 275 LKAEPASPAQDAQEPPAPPPP 295
Score = 45.4 bits (106), Expect = 3e-04
Identities = 49/175 (28%), Positives = 59/175 (33%), Gaps = 35/175 (20%)
Query: 590 PSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVT--CAALTHPRVPPLQPMGPTCPT 647
P P PPPL A S S+ V A L P +PP P+ P C
Sbjct: 229 PPPPTPPPLPPA----------------SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY 272
Query: 648 PAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAG-------PVPSARP 700
P P +P+ P PP P+P S +P A P+P P+P P
Sbjct: 273 PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLP-APPLPGVNSSSETPPPLPPKSP 331
Query: 701 ---GPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPP 752
PP A L P PP P + R G P PP PP
Sbjct: 332 SFQAPPQKAGAQALPAP---PAPPGSQPFLQKKRHGR---PGAGGGKLNPPPAPP 380
Score = 41.6 bits (96), Expect = 0.004
Identities = 39/147 (26%), Positives = 52/147 (35%), Gaps = 26/147 (17%)
Query: 966 GTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPE---PEPGLLLEVEEPGTEEERGADT 1022
G G + E +P P PPP PP P P P L PG ++T
Sbjct: 271 GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPL------PGVNS--SSET 322
Query: 1023 APTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEE---ETEDGSDKVQPP 1079
P L P++ Q ++ G PP P + P L ++ G K+ PP
Sbjct: 323 PPPLPPKSPSFQAPPQKAGAQALPAPP------APPGSQPFLQKKRHGRPGAGGGKLNPP 376
Query: 1080 PETPAEEEMETETEAEALQEKEQDDTA 1106
P PA + L K Q TA
Sbjct: 377 PAPPA------RSPTTELSSKSQQATA 397
Score = 38.9 bits (89), Expect = 0.028
Identities = 17/34 (50%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 832 LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGT 865
+P P P PP PPPPPP+ P PPP P T
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPP-PPPSAPPVST 33
Score = 38.9 bits (89), Expect = 0.028
Identities = 43/166 (25%), Positives = 53/166 (31%), Gaps = 34/166 (20%)
Query: 976 APPPPTLP---PALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
APP P +P P PPP PP P P P V PG + P +AP
Sbjct: 165 APPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTK---GNLPVVAPPV-- 219
Query: 1033 SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQ---------PPP--- 1080
P A PPP P+ PP D + K Q PPP
Sbjct: 220 -----------PCAPPPPPP--PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPL 266
Query: 1081 -ETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPP 1125
++ E + A +E L + C P P PP
Sbjct: 267 LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP 312
Score = 38.5 bits (88), Expect = 0.036
Identities = 55/230 (23%), Positives = 75/230 (32%), Gaps = 78/230 (33%)
Query: 977 PPPPTLPPALP----PPESPPKVQP-----------EPEPEPGLLLEVEE---------- 1011
PPPP LPP P PP PP P +P+ LL ++++
Sbjct: 6 PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQI 65
Query: 1012 -----------PGTEEE-------RGADTAPTLA-------PEALPS-QGEVE--REGES 1043
GT +E RGA T PTL P P+ Q +V + G+
Sbjct: 66 NDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQG 125
Query: 1044 PAAGPPPQELVEEE------PSAPPTLLEEETEDGSDKVQPP-PETPA------------ 1084
P + P L + P A P L G+ + PP P PA
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPP 185
Query: 1085 -----EEEMETETEAEALQEKEQDDTAAMLADFIDC-PPDDEKPPPPTEP 1128
+T + ++A + C PP PPPPT P
Sbjct: 186 LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP 235
Score = 35.4 bits (80), Expect = 0.31
Identities = 33/114 (28%), Positives = 38/114 (33%), Gaps = 29/114 (25%)
Query: 970 GEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
G + APP P PP PPP P P P P +L + P LAP
Sbjct: 210 GNLPVVAPPVPCAPPPPPPPPPP---TPPPLPPASVLSD-----------KAVKPQLAPL 255
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
LP PPP L+ P P L E D +PP P
Sbjct: 256 HLPPI-------------PPPLPLL--PPCGYPGLKAEPASPAQDAQEPPAPPP 294
Score = 34.7 bits (78), Expect = 0.53
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Query: 795 LPPLPPPPPSGATPPPI--APTGPPTASPPV 823
+P PPPPP PPP AP PP ++PPV
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPV 31
Score = 31.2 bits (69), Expect = 5.8
Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 8/77 (10%)
Query: 976 APPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQG 1035
APP ALP P +PP QP L+ + G G P AP A
Sbjct: 335 APPQKAGAQALPAPPAPPGSQP--------FLQKKRHGRPGAGGGKLNPPPAPPARSPTT 386
Query: 1036 EVEREGESPAAGPPPQE 1052
E+ + + A P Q+
Sbjct: 387 ELSSKSQQATAWTPTQQ 403
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo
sapiens]
Length = 1132
Score = 87.4 bits (215), Expect = 7e-17
Identities = 128/523 (24%), Positives = 187/523 (35%), Gaps = 136/523 (26%)
Query: 633 PRVPPLQPMGPTCPTPAP--VPPPEAPSPFRAPPFHPPGPMPSVGSM-PSAGPMPSAGPM 689
P PL P P PAP VPPP+ P H PGP P VG++ P A P P
Sbjct: 642 PIPKPLPVPVPPIPVPAPITVPPPQVPP-------HQPGP-PVVGALQPPAFTPPLGIPP 693
Query: 690 PSAGP-VPSARPGPPTTANHLGLSVPGL--VSVPPRLLPGPENHRAGSNEDPILAPSGTP 746
P GP VP P PP PG + +PP LP P P TP
Sbjct: 694 PGFGPGVPPPPPPPPFLR-------PGFNPMHLPPGFLP------------PGPPPPITP 734
Query: 747 PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISL-----------ESDSDDSVVIVPEGL 795
P +IPP T +P +++ D+ I ++S DSV + +
Sbjct: 735 PVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAV 794
Query: 796 PP-----LPPPP---------PSGATPPPI----AP-TGPPTASPPVPAKEEPEELPAAP 836
PP LP PP G P P+ AP TG A P + + P P P
Sbjct: 795 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP---PGMP 851
Query: 837 GP-------LPPPPPP-------PPPVPGPVTLPPPQ------------LVPEGTPGGGG 870
P +PP P P PPP PG +PPP + P G PG GG
Sbjct: 852 PPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGG 911
Query: 871 P---PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEE-----------EEDFEEEEED 916
P P ED +++ + + ++ ++++++ ++ ++ D
Sbjct: 912 PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRND 971
Query: 917 EEEYFEEEEEEE----EEFEEEFEEEEGELEEEEEEEDEEEEEELE------------EV 960
+ F ++E F E + ++ D + E ++
Sbjct: 972 NRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDL 1031
Query: 961 EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEP-------- 1012
E+ ++G E E+ K +PE G VE P
Sbjct: 1032 EERNRRSSGHRDRE--RDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVD 1089
Query: 1013 -GTEEERGADTAPTLAP-EALPSQ--GEVEREGESPAAGPPPQ 1051
+E E+G A L P E LP++ VE E +S +A P+
Sbjct: 1090 TASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR 1132
Score = 53.5 bits (127), Expect = 1e-06
Identities = 40/105 (38%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 781 ESDSDDSVVIVPEGLP-PLPP-PPPSGAT-PPPIAPTGPPTASPPVPAKEEPEEL----- 832
E+ + V +P+ LP P+PP P P+ T PPP P P PPV +P
Sbjct: 633 ETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVP--PHQPGPPVVGALQPPAFTPPLG 690
Query: 833 --PAAPGPLPPPPPPPPPVPGPVTLP---PPQLVPEGTPGGGGPP 872
P GP PPPPPPPP P P PP +P G P PP
Sbjct: 691 IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPP 735
Score = 47.8 bits (112), Expect = 6e-05
Identities = 37/122 (30%), Positives = 52/122 (42%), Gaps = 22/122 (18%)
Query: 765 FVHYDKEEASDVEISLESDSDDSVVIVPE--GLPPLPPPPPSGATPPPIAPTGPPTASPP 822
++ +DK + ++E E DS + P+ G+P P +A G S
Sbjct: 586 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENE--------VAQNGGAETSHT 637
Query: 823 VPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPE--GTP--GGGGPPALEEDL 878
P P+ LP P PP PVP P+T+PPPQ+ P G P G PPA L
Sbjct: 638 EPVSPIPKPLPV--------PVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPL 689
Query: 879 TV 880
+
Sbjct: 690 GI 691
Score = 41.6 bits (96), Expect = 0.004
Identities = 54/274 (19%), Positives = 99/274 (36%), Gaps = 24/274 (8%)
Query: 845 PPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEE 904
PPPPV + PP Q P P P+ + V + + + ++ ++ + ++ +
Sbjct: 140 PPPPVKVS-SEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPK 198
Query: 905 EEEEDFEEEEEDEEEYFEEE--------EEEEEEFE--EEFEEEEGELEEEEEEEDEEEE 954
+ + + + + E++ F E+ + +L + + +DE E
Sbjct: 199 PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEA 258
Query: 955 EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPES---PPKVQPEPEPEPGLLLEVEE 1011
E + ED T P P PA P + PP P P G+ ++
Sbjct: 259 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM----QQ 314
Query: 1012 PGTEEERGADTAPT----LAPEALPSQGEVEREGESPAAG--PPPQELVEEEPSAPPTLL 1065
P + + D + + + Q + G+ P G P P +P PPT
Sbjct: 315 PAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPP 374
Query: 1066 EEETEDGSDKVQPPPETPAEEEMETETEAEALQE 1099
++ S + Q P T + E E E +QE
Sbjct: 375 VQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 408
Score = 38.9 bits (89), Expect = 0.028
Identities = 66/315 (20%), Positives = 102/315 (32%), Gaps = 56/315 (17%)
Query: 635 VPPLQPMGPTCPTPAPV----------PPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMP 684
+ PL M APV PPP P P +P+V +PS+
Sbjct: 113 IQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFA 172
Query: 685 SAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSG 744
+ + TT + PP+ ++ + I A
Sbjct: 173 AVAQLFQ------------TTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLK 220
Query: 745 TPPPTIPPDETFGGRVPRPAFVHYDK---------EEASDVEISLESDSDDSVVIVPEG- 794
T P P E P +DK +E VE S + D+ P
Sbjct: 221 TTPTQ--PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAA 278
Query: 795 LPPLPPP-------PPSGATPPPIAPTGPPTASPPVPA--------KEEPEELPAAPGPL 839
+PP P P + + PPP AP G P PA + +P + P+
Sbjct: 279 VPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPM 338
Query: 840 --PPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEE 897
P PP +PG LP P P P P +++ +S + + E ++
Sbjct: 339 HHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP-----FQASFQAQNEPLTQK 393
Query: 898 EEEEEEEEEEEDFEE 912
++E E E+ +E
Sbjct: 394 PHQQEMEVEQPCIQE 408
Score = 38.1 bits (87), Expect = 0.048
Identities = 32/139 (23%), Positives = 51/139 (36%), Gaps = 19/139 (13%)
Query: 978 PPPTLP--PALPPPESPPKVQPE-PEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034
PPP L P +PP PP + P P PG + P + P + P +P
Sbjct: 851 PPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFA-MPPPHGMKGPFPPHGPFVRPGGMPGL 909
Query: 1035 GEVEREGESPAAG----------PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPA 1084
G G P G PP Q + +P AP +++ + QPPP
Sbjct: 910 G-----GPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQ 964
Query: 1085 EEEMETETEAEALQEKEQD 1103
++ + + ++Q+
Sbjct: 965 PQQFRNDNRQQFNSGRDQE 983
Score = 35.0 bits (79), Expect = 0.40
Identities = 40/178 (22%), Positives = 61/178 (34%), Gaps = 33/178 (18%)
Query: 974 EGAPPPPTLPPALPPPESPPKVQPEPEPEPG---------------------LLLEVEEP 1012
EG+PPPP + PP ++ P P P +L ++P
Sbjct: 137 EGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 196
Query: 1013 GTEEERGADTAPTLAPEALPSQGEV--EREGESPAAGPPPQELVEEEPSAPPTLLEEETE 1070
+ D A +A+ +Q + + E AA PPP E++ + LL+
Sbjct: 197 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPP----EQKTAFDKKLLDR--F 250
Query: 1071 DGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
D D+ + E+ E+ T A A A P PPPP P
Sbjct: 251 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAA----AAPAAASPPPPQAP 304
Score = 35.0 bits (79), Expect = 0.40
Identities = 32/127 (25%), Positives = 43/127 (33%), Gaps = 35/127 (27%)
Query: 603 QAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPF-- 660
+A ++ED+ V++ T A P P P A PPP+AP F
Sbjct: 257 EAVEESKKEDTTAVTT-------TAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPG 309
Query: 661 ------------------------RAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVP 696
+ P H P+P G MP G +P+ P A PV
Sbjct: 310 DGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPV- 368
Query: 697 SARPGPP 703
P PP
Sbjct: 369 -IPPTPP 374
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 13/113 (11%)
Query: 970 GEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
G + G PPP T P ++PPP +PP P + + E T++ + PT+
Sbjct: 722 GFLPPGPPPPITPPVSIPPPHTPPISIPN-----STIAGINEDTTKDLSIGNPIPTVVSG 776
Query: 1030 ALPSQGEVEREGESPAAGPP--PQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
A + + +A PP P L + P +LL G+ V P P
Sbjct: 777 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLL------GTQGVAPGP 823
Score = 31.6 bits (70), Expect = 4.4
Identities = 32/107 (29%), Positives = 34/107 (31%), Gaps = 44/107 (41%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PP T P +PPP P V P P P P L PG L P LP
Sbjct: 682 PPAFTPPLGIPPPGFGPGVPPPPPPPPFL-----RPGFNPMH-------LPPGFLP---- 725
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
GPPP P PP + PPP TP
Sbjct: 726 ---------PGPPP-------PITPPVSI------------PPPHTP 744
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
sapiens]
Length = 1147
Score = 87.4 bits (215), Expect = 7e-17
Identities = 128/523 (24%), Positives = 187/523 (35%), Gaps = 136/523 (26%)
Query: 633 PRVPPLQPMGPTCPTPAP--VPPPEAPSPFRAPPFHPPGPMPSVGSM-PSAGPMPSAGPM 689
P PL P P PAP VPPP+ P H PGP P VG++ P A P P
Sbjct: 657 PIPKPLPVPVPPIPVPAPITVPPPQVPP-------HQPGP-PVVGALQPPAFTPPLGIPP 708
Query: 690 PSAGP-VPSARPGPPTTANHLGLSVPGL--VSVPPRLLPGPENHRAGSNEDPILAPSGTP 746
P GP VP P PP PG + +PP LP P P TP
Sbjct: 709 PGFGPGVPPPPPPPPFLR-------PGFNPMHLPPGFLP------------PGPPPPITP 749
Query: 747 PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISL-----------ESDSDDSVVIVPEGL 795
P +IPP T +P +++ D+ I ++S DSV + +
Sbjct: 750 PVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAV 809
Query: 796 PP-----LPPPP---------PSGATPPPI----AP-TGPPTASPPVPAKEEPEELPAAP 836
PP LP PP G P P+ AP TG A P + + P P P
Sbjct: 810 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP---PGMP 866
Query: 837 GP-------LPPPPPP-------PPPVPGPVTLPPPQ------------LVPEGTPGGGG 870
P +PP P P PPP PG +PPP + P G PG GG
Sbjct: 867 PPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGG 926
Query: 871 P---PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEE-----------EEDFEEEEED 916
P P ED +++ + + ++ ++++++ ++ ++ D
Sbjct: 927 PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRND 986
Query: 917 EEEYFEEEEEEE----EEFEEEFEEEEGELEEEEEEEDEEEEEELE------------EV 960
+ F ++E F E + ++ D + E ++
Sbjct: 987 NRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDL 1046
Query: 961 EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEP-------- 1012
E+ ++G E E+ K +PE G VE P
Sbjct: 1047 EERNRRSSGHRDRE--RDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVD 1104
Query: 1013 -GTEEERGADTAPTLAP-EALPSQ--GEVEREGESPAAGPPPQ 1051
+E E+G A L P E LP++ VE E +S +A P+
Sbjct: 1105 TASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR 1147
Score = 53.5 bits (127), Expect = 1e-06
Identities = 40/105 (38%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 781 ESDSDDSVVIVPEGLP-PLPP-PPPSGAT-PPPIAPTGPPTASPPVPAKEEPEEL----- 832
E+ + V +P+ LP P+PP P P+ T PPP P P PPV +P
Sbjct: 648 ETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVP--PHQPGPPVVGALQPPAFTPPLG 705
Query: 833 --PAAPGPLPPPPPPPPPVPGPVTLP---PPQLVPEGTPGGGGPP 872
P GP PPPPPPPP P P PP +P G P PP
Sbjct: 706 IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPP 750
Score = 47.8 bits (112), Expect = 6e-05
Identities = 37/122 (30%), Positives = 52/122 (42%), Gaps = 22/122 (18%)
Query: 765 FVHYDKEEASDVEISLESDSDDSVVIVPE--GLPPLPPPPPSGATPPPIAPTGPPTASPP 822
++ +DK + ++E E DS + P+ G+P P +A G S
Sbjct: 601 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENE--------VAQNGGAETSHT 652
Query: 823 VPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPE--GTP--GGGGPPALEEDL 878
P P+ LP P PP PVP P+T+PPPQ+ P G P G PPA L
Sbjct: 653 EPVSPIPKPLPV--------PVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPL 704
Query: 879 TV 880
+
Sbjct: 705 GI 706
Score = 41.6 bits (96), Expect = 0.004
Identities = 54/274 (19%), Positives = 99/274 (36%), Gaps = 24/274 (8%)
Query: 845 PPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEE 904
PPPPV + PP Q P P P+ + V + + + ++ ++ + ++ +
Sbjct: 155 PPPPVKVS-SEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPK 213
Query: 905 EEEEDFEEEEEDEEEYFEEE--------EEEEEEFE--EEFEEEEGELEEEEEEEDEEEE 954
+ + + + + E++ F E+ + +L + + +DE E
Sbjct: 214 PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEA 273
Query: 955 EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPES---PPKVQPEPEPEPGLLLEVEE 1011
E + ED T P P PA P + PP P P G+ ++
Sbjct: 274 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM----QQ 329
Query: 1012 PGTEEERGADTAPT----LAPEALPSQGEVEREGESPAAG--PPPQELVEEEPSAPPTLL 1065
P + + D + + + Q + G+ P G P P +P PPT
Sbjct: 330 PAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPP 389
Query: 1066 EEETEDGSDKVQPPPETPAEEEMETETEAEALQE 1099
++ S + Q P T + E E E +QE
Sbjct: 390 VQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 423
Score = 38.9 bits (89), Expect = 0.028
Identities = 66/315 (20%), Positives = 102/315 (32%), Gaps = 56/315 (17%)
Query: 635 VPPLQPMGPTCPTPAPV----------PPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMP 684
+ PL M APV PPP P P +P+V +PS+
Sbjct: 128 IQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFA 187
Query: 685 SAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSG 744
+ + TT + PP+ ++ + I A
Sbjct: 188 AVAQLFQ------------TTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLK 235
Query: 745 TPPPTIPPDETFGGRVPRPAFVHYDK---------EEASDVEISLESDSDDSVVIVPEG- 794
T P P E P +DK +E VE S + D+ P
Sbjct: 236 TTPTQ--PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAA 293
Query: 795 LPPLPPP-------PPSGATPPPIAPTGPPTASPPVPA--------KEEPEELPAAPGPL 839
+PP P P + + PPP AP G P PA + +P + P+
Sbjct: 294 VPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPM 353
Query: 840 --PPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEE 897
P PP +PG LP P P P P +++ +S + + E ++
Sbjct: 354 HHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP-----FQASFQAQNEPLTQK 408
Query: 898 EEEEEEEEEEEDFEE 912
++E E E+ +E
Sbjct: 409 PHQQEMEVEQPCIQE 423
Score = 38.1 bits (87), Expect = 0.048
Identities = 32/139 (23%), Positives = 51/139 (36%), Gaps = 19/139 (13%)
Query: 978 PPPTLP--PALPPPESPPKVQPE-PEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034
PPP L P +PP PP + P P PG + P + P + P +P
Sbjct: 866 PPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFA-MPPPHGMKGPFPPHGPFVRPGGMPGL 924
Query: 1035 GEVEREGESPAAG----------PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPA 1084
G G P G PP Q + +P AP +++ + QPPP
Sbjct: 925 G-----GPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQ 979
Query: 1085 EEEMETETEAEALQEKEQD 1103
++ + + ++Q+
Sbjct: 980 PQQFRNDNRQQFNSGRDQE 998
Score = 35.0 bits (79), Expect = 0.40
Identities = 40/178 (22%), Positives = 61/178 (34%), Gaps = 33/178 (18%)
Query: 974 EGAPPPPTLPPALPPPESPPKVQPEPEPEPG---------------------LLLEVEEP 1012
EG+PPPP + PP ++ P P P +L ++P
Sbjct: 152 EGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211
Query: 1013 GTEEERGADTAPTLAPEALPSQGEV--EREGESPAAGPPPQELVEEEPSAPPTLLEEETE 1070
+ D A +A+ +Q + + E AA PPP E++ + LL+
Sbjct: 212 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPP----EQKTAFDKKLLDR--F 265
Query: 1071 DGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
D D+ + E+ E+ T A A A P PPPP P
Sbjct: 266 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAA----AAPAAASPPPPQAP 319
Score = 35.0 bits (79), Expect = 0.40
Identities = 32/127 (25%), Positives = 43/127 (33%), Gaps = 35/127 (27%)
Query: 603 QAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPF-- 660
+A ++ED+ V++ T A P P P A PPP+AP F
Sbjct: 272 EAVEESKKEDTTAVTT-------TAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPG 324
Query: 661 ------------------------RAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVP 696
+ P H P+P G MP G +P+ P A PV
Sbjct: 325 DGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPV- 383
Query: 697 SARPGPP 703
P PP
Sbjct: 384 -IPPTPP 389
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 13/113 (11%)
Query: 970 GEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
G + G PPP T P ++PPP +PP P + + E T++ + PT+
Sbjct: 737 GFLPPGPPPPITPPVSIPPPHTPPISIPN-----STIAGINEDTTKDLSIGNPIPTVVSG 791
Query: 1030 ALPSQGEVEREGESPAAGPP--PQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
A + + +A PP P L + P +LL G+ V P P
Sbjct: 792 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLL------GTQGVAPGP 838
Score = 31.6 bits (70), Expect = 4.4
Identities = 32/107 (29%), Positives = 34/107 (31%), Gaps = 44/107 (41%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PP T P +PPP P V P P P P L PG L P LP
Sbjct: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFL-----RPGFNPMH-------LPPGFLP---- 740
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
GPPP P PP + PPP TP
Sbjct: 741 ---------PGPPP-------PITPPVSI------------PPPHTP 759
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 87.4 bits (215), Expect = 7e-17
Identities = 77/258 (29%), Positives = 92/258 (35%), Gaps = 34/258 (13%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPF------HPPGPMPSVGSMPSAGPMPSA 686
P+ P P PTP V PP A PF P PS P+A P+P
Sbjct: 996 PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055
Query: 687 GPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTP 746
P A +PS + GP T S+ G + P P P+ G P +P G P
Sbjct: 1056 APTTPAATLPSPKGGPATP------SLKGAPTPPAATPPSPK----GGPATP--SPKGAP 1103
Query: 747 -PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLP---PPP 802
PP P GG P K + + S P+G P P PP
Sbjct: 1104 MPPAATPPSPKGGLATPP-----HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158
Query: 803 PSG--ATPPPIAPTGPPTASPPVP----AKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP 856
P G ATPPP P A+PP P A P+ P P PP P P P P
Sbjct: 1159 PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218
Query: 857 -PPQLVPEGTPGGGGPPA 873
P P GG P+
Sbjct: 1219 TTPAATPPSPKGGLATPS 1236
Score = 87.0 bits (214), Expect = 9e-17
Identities = 75/257 (29%), Positives = 91/257 (35%), Gaps = 32/257 (12%)
Query: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPV 695
PP GP P+P P P A +P +P P P P P A PS P+A P
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATP-PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 696 PSARPGPPTTANHLGLSVP-------GLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPP 748
P PP P G + P LP P+ G P L + TPP
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK----GGPATPSLKGAPTPPA 1084
Query: 749 TIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVP--EGLPPLP---PPPP 803
PP G P P + + + + S + P +G P P PP P
Sbjct: 1085 ATPPSPKGGPATPSP--------KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Query: 804 SG--ATPPPIAPTGPPTASPPVP----AKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP- 856
G ATPPP P A+PP P A P+ P P PP P P P P
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 857 PPQLVPEGTPGGGGPPA 873
P P GG P+
Sbjct: 1197 TPAATPPSPKGGLATPS 1213
Score = 83.2 bits (204), Expect = 1e-15
Identities = 80/268 (29%), Positives = 90/268 (33%), Gaps = 42/268 (15%)
Query: 629 ALTHPRVPPLQPMGPTCPTPAP-----VPPPEAPSPFRAP--PFHPPGPMPSVGSMPS-- 679
A T P P P G TP P P PSP P P P P + PS
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091
Query: 680 ---AGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNE 736
A P P PMP A PS + GL+ P P P + + G
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKG---------GLATPPHKGAPTTPAATPPSPKGGLAT 1142
Query: 737 DPILAPSGTP--PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794
P P G P P PP G P P K + + S P+G
Sbjct: 1143 PP---PKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATPSPKG 1193
Query: 795 LPPLP---PPPPSG--ATPPPIAPTGPPTASPPVP----AKEEPEELPAAPGPLPPPPPP 845
P P PP P G ATP P P A+PP P A P+ P P PP P
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253
Query: 846 PPPVPGPVTLP-PPQLVPEGTPGGGGPP 872
P P P P PP P GG P
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATP 1281
Score = 80.1 bits (196), Expect = 1e-14
Identities = 81/282 (28%), Positives = 96/282 (34%), Gaps = 63/282 (22%)
Query: 629 ALTHPRVPPLQPMGPTCP-----------TPAPVPPPEAPSPFRAPPFHPPGPMP-SVGS 676
A T V PL P G T P P P P P+P +AP P +
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA 923
Query: 677 MPS-----AGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHR 731
P+ A P P P P A PS + GP T + P PP P P
Sbjct: 924 TPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS-------PKWAPTPPAATP-PSPKG 975
Query: 732 AGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIV 791
+ P AP TPP PP G P P K + ++ S
Sbjct: 976 GPATPSPKGAP--TPPAATPPSPKGGPATPSP------KGAPTPPAVTPPS--------- 1018
Query: 792 PEGLPPLPPPPPSGATPP---PIAPTGPPTASP--------PVPAKEEPEELPAAP---- 836
P+G P P P +TPP P +P G P A+P P P+ PA P
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 837 GPLPPPPPPPPPVPGPVTLP------PPQLVPEGTPGGGGPP 872
P PP PP P GP T PP P GG P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Score = 79.3 bits (194), Expect = 2e-14
Identities = 83/295 (28%), Positives = 99/295 (33%), Gaps = 65/295 (22%)
Query: 628 AALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPS-----AGP 682
A L P+ P P PTP PP +P A P PMP + PS A P
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPP-SPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 683 MPSAGPMPSAGPVPSARPG----PPTTANHLGLSVP-----GLVSVPPRLLPGPENHRAG 733
P A PS + G PP A + P GL + PP+ P
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Query: 734 SNEDPILAPS----GTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVV 789
S + + PS T P PP G P P K + + S
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP------KGAPTTPAATPPSPKGGLAT 1234
Query: 790 IVPEGLPPLP---PPPPSG--ATPPPIAPTGPPTASPPV--------------------- 823
P+G P P PP P G ATPPP PP A+PP
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 824 ------PAKEEPEELPAAPGPLPPPP------PPPPPVPGPVTLPPPQLVPEGTP 866
PA P+ P P PP P PPP P P + PP P+GTP
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS--PKGTP 1347
Score = 77.8 bits (190), Expect = 5e-14
Identities = 83/283 (29%), Positives = 100/283 (35%), Gaps = 51/283 (18%)
Query: 625 VTCAALTHPRVPPLQPMGPTCPTPAPVPPPEA---PSPFRAPPFHPP--GPMPSVGSMPS 679
+T ++ R P P P+P P P A PSP P P P P + PS
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 680 -----AGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGS 734
A P P P P A PS + GP T S G + P P P+ A +
Sbjct: 973 PKGGPATPSPKGAPTPPAATPPSPKGGPATP------SPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 735 NEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794
P + TPP PP PA K + +L S +G
Sbjct: 1027 ---PFPKGASTPPAATPPSPK-----GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 795 LPPLP---PPPPSG--ATPPPIAPTGPPTASPPVP----AKEEPEELPAAPGPLPPPP-- 843
P P PP P G ATP P PP A+PP P A + P P PP P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 844 ----PPP----------PPVP-GPVTLPPPQLVPEGTPGGGGP 871
PPP PP P G + PPP+ P TP P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT-TPAATPP 1180
Score = 77.4 bits (189), Expect = 7e-14
Identities = 83/280 (29%), Positives = 100/280 (35%), Gaps = 49/280 (17%)
Query: 636 PPLQPMGPTCPTP--APVPP---PEAPSPFRAPPFHPPGPMPSVGSMPS-----AGPMPS 685
PP GP P+P AP+PP P +P A P H P + PS A P P
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Query: 686 AGPMPSAGPVPSARPG----PPTTANHLGLSVP-----GLVSVPPRLLPGPENHRAGSNE 736
P A PS + G PP A + P GL + P+ P S +
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206
Query: 737 DPILAPSG----TPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVP 792
+ PS T P PP G P P K + + S P
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSP------KGAPTTPAATPPSPKGGPATPPP 1260
Query: 793 EGLPPLP---PPPPSG--ATPP-----------PIAPTGPPTASPPVPAKEEPEELPAAP 836
+G P P PP G ATPP P +P G P SPP A P P +P
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
Query: 837 GPLP-PPPPPPPPVPGPVTLPPPQ---LVPEGTPGGGGPP 872
P PPP P P VT P P+ +P TP G P
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Score = 76.6 bits (187), Expect = 1e-13
Identities = 78/278 (28%), Positives = 98/278 (35%), Gaps = 43/278 (15%)
Query: 628 AALTHPRVPPLQPMGPTCPTP--APVPPPEAPSPFR---APPFHPPGPMPSVGSMPSAGP 682
A T PP GP P P AP PP P + A P H P P+V + PS
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299
Query: 683 MPSAGPMPSAGPVPSARP----GPPTTANHLGLSVPGLVSVP-----PRLLPGPENHRAG 733
P+ P A P+A P G P T G P V+ P P L + + G
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 734 ----SNEDPILAPSGTP-----PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDS 784
S+++ P+ TP P PP G +P P + S I L
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP-----KGDPTSPAVIPLSPKK 1414
Query: 785 DDSVVIVPEGLPPLPPPPPSGATPPPIAP--------TGPPTASPPVPAKEEPEELPAAP 836
+ + EG P TPP + P T P P P+ + LPA
Sbjct: 1415 APATPVTREG---AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 837 GPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
P P PP P V T P+ P TP G P L
Sbjct: 1472 PPSPKEPPAPKQV---ATSSSPKKAP-ATPAPMGAPTL 1505
Score = 72.8 bits (177), Expect = 2e-12
Identities = 84/318 (26%), Positives = 104/318 (32%), Gaps = 85/318 (26%)
Query: 631 THPRVPPLQPMGPTCPTP------------APVPPPEAPSPFRAPPFHPPGP-------- 670
T P VP P P+P AP P PSP P PPG
Sbjct: 697 TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISH 756
Query: 671 ---MPSVGSMPSAGPMPSAG-----------------PMPSAGPVPSARPGPPTTANHLG 710
+ V S P P +G P P V PPT G
Sbjct: 757 TSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAG 816
Query: 711 LSVP-GLVSVPPRLLPG---PENHRA--GSNEDPILAPSGTPPP---------------- 748
P G +S P + PEN + GS + P S TPP
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 749 --TIPPDETFGGRVPRPAFVH--YDKE--------EASDVEISLESDSDDSVVIVPEGLP 796
T+PP ET P P+ V+ + KE +A + ++ S P+G+P
Sbjct: 877 GVTLPPKET-----PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP 931
Query: 797 PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP 856
P P GA PP A P P P+ P+ P P PP P P P P P
Sbjct: 932 A--SPSPKGAPTPPAATPPSPKGGPATPS---PKWAPTPPAATPPSPKGGPATPSPKGAP 986
Query: 857 -PPQLVPEGTPGGGGPPA 873
PP P GG P+
Sbjct: 987 TPPAATPPSPKGGPATPS 1004
Score = 72.0 bits (175), Expect = 3e-12
Identities = 71/246 (28%), Positives = 89/246 (36%), Gaps = 34/246 (13%)
Query: 644 TCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPP 703
T +P P P AP+P P P G ++P P P PS +P + GP
Sbjct: 852 TTHSPTPPSPKGAPTPSAVTPLSPKGV-----TLP-----PKETPTPSVVNLPFPKEGPA 901
Query: 704 TTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRP 763
T A ++ S P + P ++ P AP TPP PP G P P
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP--TPPAATPPSPKGGPATPSP 959
Query: 764 AFVHYDKEEASDVEISLESDSDDSVVIVPEGLPP----LPPPPPSG-ATPPPIAPTGPPT 818
K + + S P+G P PP P G ATP P PP
Sbjct: 960 ------KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 819 ASPPVPAKEEPEELPAAPG-PLPPPPPPPPPVPGPVTLPPPQLVPEGTP--------GGG 869
+PP P K P P G PP PP P P P P+ P TP GG
Sbjct: 1014 VTPPSP-KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT-TPAATLPSPKGGP 1071
Query: 870 GPPALE 875
P+L+
Sbjct: 1072 ATPSLK 1077
Score = 65.9 bits (159), Expect = 2e-10
Identities = 73/267 (27%), Positives = 89/267 (33%), Gaps = 40/267 (14%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPM--PSVGSMPSAG----PMPSA 686
P P P P P PP AP+ A P P G + PS P+ P P
Sbjct: 1149 PTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207
Query: 687 G---PMPSAGPV-PSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP 742
G P P P P+A P P GL+ P P P + + G P P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKG----GLATPSPKGAPTTPAATPPSPKGGPATPP---P 1260
Query: 743 SGTP-PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPP- 800
G P PP P GG P K + ++ S P+G P P
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPP-----HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315
Query: 801 -----------PPPSGA-TPP---PIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPP 845
PPP GA TPP P +P G PT P+ + P++ PP
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 846 PPPVPGPVTLPPPQLVPEGTPGGGGPP 872
P GP PP P G P
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Score = 61.6 bits (148), Expect = 4e-09
Identities = 76/268 (28%), Positives = 91/268 (33%), Gaps = 44/268 (16%)
Query: 629 ALTHPRVPPLQPMG----------PTCPTPAPVPPP---EAPSPFRAPPFHPPGPMPSVG 675
A T P P P G PT P P P PSP + P P PS
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPK 1252
Query: 676 SMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSN 735
P A P P P P A PS + G T H G P +V+ PP GP +
Sbjct: 1253 GGP-ATPPPKGAPTPPAATPPSLKGGLATPP-HKGAPNPAVVT-PPSPKGGP------AT 1303
Query: 736 EDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGL 795
P AP TPP PP P P K + ++ S P+G
Sbjct: 1304 SPPKGAP--TPPAATPPSPKGSPGTPPP------KGAPTPPAVTPPS---------PKGT 1346
Query: 796 PPLPPPPPS--GATPPPIAPTGPPTASPPVPAKEEPEELPAAP--GPLPPPPPPPPPVPG 851
P LP PS G P + GP + K P P +P GP P P P P
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406
Query: 852 PVTLPPPQLVPEGTPGGGGPPALEEDLT 879
+ L P + G + DLT
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLT 1434
Score = 61.6 bits (148), Expect = 4e-09
Identities = 68/273 (24%), Positives = 96/273 (35%), Gaps = 38/273 (13%)
Query: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSM-PSAGPM--PSAGPMP-S 691
PP GP P+P P A P +P P P+ G+ PS G + P+ P+
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPL-SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444
Query: 692 AGPVPSARPGPPTTANHLG-LSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPP--- 747
P SA G P T + G ++P + P+ P P+ + ++ P AP+ P
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK--QVATSSSPKKAPATPAPMGA 1502
Query: 748 PTIP----------PDETFGGRVP-RPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLP 796
PT+P P R P P K+ + + V P+ P
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 797 PLPPPPPSGATPPPIAPTGPPTASP---------------PVPAKEEPEELPAAPGPLPP 841
+P P + ATP + PP +P P P+E P P PP
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622
Query: 842 PPPPPPPVPGPVTLP-PPQLVPEGTPGGGGPPA 873
P P P P P P + P PA
Sbjct: 1623 SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655
Score = 61.6 bits (148), Expect = 4e-09
Identities = 124/557 (22%), Positives = 184/557 (33%), Gaps = 111/557 (19%)
Query: 477 SPRGSPDGSLQTGKPSAPKKLKLDVGEAMAPPSHRKGDSN-ANSDVCAAALR--GLSRTI 533
SP+ P G P++P + L +A A P R+G + + D+ A+ L +
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447
Query: 534 LMCGPLIKEETHRRLHDLVLPLVMGVQQGE-------VLGSSPYTSSRCRRELYCLLLAL 586
P T D LP V E SSP + + L
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507
Query: 587 LLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCP 646
++ SP+ P A +R+ ++ S+ A +PP +
Sbjct: 1508 VIPSSPKEVP-------ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 647 TPAPVPPPEAPS----------PFRAPPFHPPGPMPSVGSMPSA--GPMPSAGPMPSAGP 694
TPA P EAP+ P P + P P +P A P P P P A
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 695 VPSARPGPPTTAN--------------------------HLGLSVPGLVSVPPR------ 722
PS GP T A +G +VP P
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
Query: 723 -----LLPGPENH---RAGSNEDPILAPSGTPPPTIPPDETF--GGRVP----RPA-FVH 767
+ P PE+ A + + P S P I PD + G + P PA +
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740
Query: 768 YDKEEASDVEISLESDSDDSVVIVPEGLPP-----------LPPPPPSGATPPPIAPTGP 816
K+ + + S S + PE LP P + + P P
Sbjct: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
Query: 817 PTASPPVPAKEEPEE-LPAAPG--------PLPP-------PPPPPPPVPGPVTLPPPQL 860
P A PVP ++ LP++PG PL P P PP P+ G V L
Sbjct: 1801 PLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF-QSVL 1859
Query: 861 VPEGTPGGGG----PPALEEDLTVININS---SDEEEEEEEEEEEEEEEEEEEEEDFEEE 913
V TP G P+ ++ +T N S SD +E E EE++ + ++
Sbjct: 1860 VNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAA 1919
Query: 914 EEDEEEYFEEEEEEEEE 930
E +EE + ++ E
Sbjct: 1920 AEIDEEPVSKAKQSRSE 1936
Score = 41.2 bits (95), Expect = 0.006
Identities = 38/168 (22%), Positives = 60/168 (35%), Gaps = 15/168 (8%)
Query: 969 GGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL-- 1026
GG + PTLP PP PK P P+ + P T GA T P +
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPS---PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP 1510
Query: 1027 -APEALPSQGEVEREGESPAA----GPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPE 1081
+P+ +P+ R+ +P A P L +E PP + + + + P E
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK-TPAIPTPKE 1569
Query: 1082 TPAEEEMETETEAEALQEKEQDDTAA----MLADFIDCPPDDEKPPPP 1125
PA + + A+ + ++ + P E P PP
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Score = 39.3 bits (90), Expect = 0.021
Identities = 42/160 (26%), Positives = 58/160 (36%), Gaps = 26/160 (16%)
Query: 977 PPPPTLPPALPPPE---SPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL---APEA 1030
PP P PA P P+ +PP P P P+ G P T +GA T P + +P+
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATP-PSPKGG-------PATPSPKGAPTPPAVTPPSPKG 1021
Query: 1031 LPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP--PETPAEEEM 1088
P+ + +P A PP + P+A P T + P P TP+ +
Sbjct: 1022 SPAATPFPKGASTPPAATPPSP--KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 1089 ETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
T A K T + P PP T P
Sbjct: 1080 PTPPAATPPSPKGGPATPS--------PKGAPMPPAATPP 1111
Score = 38.9 bits (89), Expect = 0.028
Identities = 48/177 (27%), Positives = 65/177 (36%), Gaps = 36/177 (20%)
Query: 977 PPPPTLPPALPPPE---SPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT-----LAP 1028
PP P P PPP+ +PP V P P P+ L P + +G T P+ P
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTP-PSPKGTPTLPATTPSS---KGGPTTPSSKEGPTPP 1372
Query: 1029 EALPS-QGEVEREGESPAAGP--------PPQELV-----EEEPSAPPTLLEEETEDGSD 1074
A PS +G SP GP P V ++ P+ P T T D
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 1075 KVQPPPETPAEEEMETETEA----EALQEKEQDDTAAMLADFIDCPPDDEKPPPPTE 1127
+ PP TP + T A A + D T + PP ++PP P +
Sbjct: 1433 -LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT-----PPSPKEPPAPKQ 1483
Score = 38.1 bits (87), Expect = 0.048
Identities = 33/110 (30%), Positives = 39/110 (35%), Gaps = 19/110 (17%)
Query: 977 PPPPTLPPALPPPE---SPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPS 1033
PP P PA P P+ +PP P P P+ G P T +GA T P P + P
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATP-PSPKGG-------PATPSPKGAPTPPAATPPS-PK 997
Query: 1034 QGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
G SP P P + P P T PP TP
Sbjct: 998 GGPAT---PSPKGAPTPPAVTPPSPKGSPA----ATPFPKGASTPPAATP 1040
Score = 37.7 bits (86), Expect = 0.062
Identities = 60/253 (23%), Positives = 85/253 (33%), Gaps = 84/253 (33%)
Query: 621 SEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAP--SPFRAPPFHPPGPMPSVGSMP 678
S AL AAL P GPT P P P + P + +A PF P ++ S P
Sbjct: 29 SSALSVTAALGQP--------GPTLPPPCSPAPQQCPLSAANQASPFPSPS---TIASTP 77
Query: 679 SAGPMPSAG-----PMPSAGPVPSARP---GPPTTANHLGLSVPGLVSVPPRLLPGPENH 730
P P + P+ +A P+ P GPP + L L+
Sbjct: 78 LEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALA------------------ 119
Query: 731 RAGSNEDPILAPS--GTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSV 788
P++AP+ GTP + P ++L V
Sbjct: 120 ------SPMIAPTLKGTPSSSAP--------------------------LAL-------V 140
Query: 789 VIVPEGLPPLPPPPPSGATPPP---IAPTGPP-TASPPVPAKEEPEELPAAPGPLPPPPP 844
+ P + PP+ T PP +A +G T S P+ E L P + P P
Sbjct: 141 ALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPK 200
Query: 845 PPPPVPGPVTLPP 857
P P V+ P
Sbjct: 201 GTPSPPCIVSTVP 213
Score = 37.7 bits (86), Expect = 0.062
Identities = 38/159 (23%), Positives = 55/159 (34%), Gaps = 15/159 (9%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PP P PA PP+ P P P PGT +GA T P + P + +G
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSP-----KGSPGTPPPKGAPTPPAVTPPS--PKGT 1346
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP-----PETPAEEEMETE 1091
+P++ P +E PP + G + PP P P+ + T
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPA--ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404
Query: 1092 TEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
L K+ T + + P + PP P S
Sbjct: 1405 PAVIPLSPKKAPAT-PVTREGAATPSKGDLTPPAVTPVS 1442
Score = 35.0 bits (79), Expect = 0.40
Identities = 35/114 (30%), Positives = 42/114 (36%), Gaps = 30/114 (26%)
Query: 977 PPPPTLPPALPPPES---PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPS 1033
PP P PA P P+ PP P P P+ GL T +GA T P P + P
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATP-PSPKGGL-------ATPPHKGAPTTPAATPPS-PK 1137
Query: 1034 QGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP---PETPA 1084
G A PPP+ + PP + G PP P TPA
Sbjct: 1138 GG---------LATPPPKGAPTTPAATPP------SPKGGLATPPPKGAPTTPA 1176
Score = 34.3 bits (77), Expect = 0.69
Identities = 26/107 (24%), Positives = 38/107 (35%), Gaps = 5/107 (4%)
Query: 983 PPALPPPES---PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVER 1039
P L P E+ P P P+ P + E P T + A + P + P +
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598
Query: 1040 EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQP--PPETPA 1084
PA P + P+ P E+ + K P PP TP+
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645
Score = 33.1 bits (74), Expect = 1.5
Identities = 33/117 (28%), Positives = 41/117 (35%), Gaps = 18/117 (15%)
Query: 977 PPPPTLPPALPPPESPP--KVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034
PP P A PPP+ P P P+ GL T +GA T P P + P
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGL-------ATPSPKGAPTTPAATPPS-PKG 1207
Query: 1035 G----EVEREGESPAAGPPPQE--LVEEEPSAPPT--LLEEETEDGSDKVQPPPETP 1083
G + +PAA PP + L P PT + G PP P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264
Score = 32.7 bits (73), Expect = 2.0
Identities = 31/116 (26%), Positives = 39/116 (33%), Gaps = 15/116 (12%)
Query: 967 TAGGEVEEGAPPPPTLPPALPPPE---SPPKVQPEPEPEPGLLLEVEEPGTEEERGADTA 1023
T+ + A P P PA P P+ +PP P P P+ G P T + A T
Sbjct: 914 TSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-PSPKGG-------PATPSPKWAPTP 965
Query: 1024 PTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP 1079
P P + P G SP P P P P + V PP
Sbjct: 966 PAATPPS-PKGGPAT---PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017
Score = 32.7 bits (73), Expect = 2.0
Identities = 37/140 (26%), Positives = 52/140 (37%), Gaps = 13/140 (9%)
Query: 972 VEEGAPPPPTLPPA-LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE- 1029
V PP +LP A P P PPK Q P PGL+LE + P + PE
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPS-SPGLVLESPSKPLAPADEDELLPLIPPEP 1848
Query: 1030 ---ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDG--SDKVQPPPETPA 1084
+P Q + +AG P PSA + + G SD + PE
Sbjct: 1849 ISGGVPFQSVLVNMPTPKSAGIP-----VPTPSAKQPVTKNNKGSGTESDSDESVPELEE 1903
Query: 1085 EEEMETETEAEALQEKEQDD 1104
++ + T+ L + D
Sbjct: 1904 QDSTQATTQQAQLAAAAEID 1923
Score = 32.0 bits (71), Expect = 3.4
Identities = 29/95 (30%), Positives = 36/95 (37%), Gaps = 16/95 (16%)
Query: 977 PPPPTLPPALPPPESPP--KVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034
PP P A PPP+ P P P+ GL T +GA T P P + P
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGL-------ATPPPKGAPTTPAATPPS-PKG 1184
Query: 1035 G----EVEREGESPAAGPPPQE--LVEEEPSAPPT 1063
G + +PAA PP + L P PT
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
Score = 31.6 bits (70), Expect = 4.4
Identities = 37/136 (27%), Positives = 46/136 (33%), Gaps = 22/136 (16%)
Query: 940 GELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLP-PALPPPESPP----- 993
GE E ++E + E L +A P PTLP P P P+ P
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
Query: 994 KVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA---LPSQGEVEREGESPAAGPP- 1049
+ P P P +E P + G APEA LP+ GPP
Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPN-----------LIGPPI 111
Query: 1050 -PQELVEEEPSAPPTL 1064
P L P PTL
Sbjct: 112 SPAALALASPMIAPTL 127
Score = 31.2 bits (69), Expect = 5.8
Identities = 31/127 (24%), Positives = 37/127 (29%), Gaps = 12/127 (9%)
Query: 969 GGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEE-----PGTEEERGADTA 1023
GG PT P A PP P P+ P P T +GA T
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP 1266
Query: 1024 PTLAPEALPS--QGEVEREGESPAAGPPPQELVEEEPSAP-----PTLLEEETEDGSDKV 1076
P P +L + +PA PP S P P + GS
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Query: 1077 QPPPETP 1083
PP P
Sbjct: 1327 PPPKGAP 1333
Score = 30.8 bits (68), Expect = 7.6
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 791 VPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPP 847
V EG P P+ + P+AP+ T +P PE + P P PP PP
Sbjct: 690 VKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPP 746
Score = 30.4 bits (67), Expect = 9.9
Identities = 62/259 (23%), Positives = 86/259 (33%), Gaps = 25/259 (9%)
Query: 597 PLACALQAFS-LGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPE 655
P++ AL + LGQ +L CS A C + P TP VP P+
Sbjct: 27 PMSSALSVTAALGQPGPTLPPP--CSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQ 84
Query: 656 APSPF--------RAPPFHPP--GPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTT 705
+ S AP F P GP S ++ A PM P P SA
Sbjct: 85 SSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM--IAPTLKGTPSSSAPLALVAL 142
Query: 706 ANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPIL--APSGTPPPTIPPDETFGGRVPRP 763
A H SV + PP LL P + + I AP P ++ VP P
Sbjct: 143 APH---SVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP 199
Query: 764 AFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPV 823
S V + + + G+ LP P+ T S +
Sbjct: 200 KGTPSPPCIVSTVPYHCVT----PMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVL 255
Query: 824 PAKEEPEELPAAPGPLPPP 842
+ + P L + GP+ PP
Sbjct: 256 ISPQNPGSL-SLKGPVSPP 273
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 86.7 bits (213), Expect = 1e-16
Identities = 82/256 (32%), Positives = 96/256 (37%), Gaps = 47/256 (18%)
Query: 643 PTCPTPAPVPPPEAPSPFRAPPFHPP--GPMPSVG---SMPSAGPMPSAGPMPSAGPVPS 697
P P P P+ R P PP P++G S P A P PSA P PSA P
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Query: 698 ARPGPPTTANHLGLSVPG--LVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDET 755
P PP T + G + LP P L+P TPPP PP
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-----------LSPLATPPPQAPP--- 359
Query: 756 FGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLP-PPPPSGATPPPIAPT 814
+ P AS L + S + + L P PPPS PP AP
Sbjct: 360 ---ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS---PPVQAPF 413
Query: 815 GPPTASPPV-----PAKEEPEELPAAPGPLPPPPP----------PPPPVPGPVTLPPPQ 859
PP ASPPV P + P L A P +PP PP PPP P P+ PP Q
Sbjct: 414 SPP-ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472
Query: 860 LV---PEGTPGGGGPP 872
L P+ P PP
Sbjct: 473 LAKPPPQAPPALATPP 488
Score = 80.9 bits (198), Expect = 6e-15
Identities = 83/295 (28%), Positives = 105/295 (35%), Gaps = 71/295 (24%)
Query: 590 PSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQ-PMGPTCP-- 646
PSP PPL+ A Q ++L V + A + P PP+Q P P
Sbjct: 370 PSPPASPPLSPL--ATPSPQAPNALAVH-------LLQAPFSPPPSPPVQAPFSPPASPP 420
Query: 647 -TPAPVPPPEAPSPFRAPPFH-PPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPT 704
+P+ PP +AP APP PP P S PSA P P A P +A P+ A+P P
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480
Query: 705 TANHLGLSVPGLVSVPPRLLPGPENHRAGS-----NEDPILAPSGTPPPTIPPDETFGGR 759
P L + P + LP P G + ++P TPPP PP
Sbjct: 481 P--------PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP------- 525
Query: 760 VPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTA 819
++ L +PP PP A+P AP PPT
Sbjct: 526 ------------------------------VLAAPLLQVPPSPP--ASPTLQAPRRPPTP 553
Query: 820 SPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
P L APGP PPPP TL P L + P L
Sbjct: 554 GPDTSVSGPRLTLALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603
Score = 79.0 bits (193), Expect = 2e-14
Identities = 98/318 (30%), Positives = 117/318 (36%), Gaps = 76/318 (23%)
Query: 584 LALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQ--PM 641
LA+ L +P PPP FS ++ S+A + AA PPLQ P
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA------PPLQVPPS 445
Query: 642 GPTCP--TPAPVPPPEAPSPFRAPPFH--------PPG----PMPSVGSMPSAGP----- 682
P P +P+ PPP+AP P APP PP P+ ++ S P++ P
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 683 MPSAG-PM-PSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRL-------LPGPENHRAG 733
PSA PM P A P P A PP A L L VP P L PGP+ +G
Sbjct: 506 SPSASLPMSPLATPPPQA---PPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561
Query: 734 SNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPE 793
LAP PPP+ P T G P + S E DS PE
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSG----PDLAGHSSSATSTPEELRGYDSG------PE 611
Query: 794 GLPPLPPPPP-----------SGATPPPIAPTGPPTASPPVPAK---------------E 827
G PPP S PP+A G P A P P E
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 671
Query: 828 EPEELPAAPGPLPPPPPP 845
PE APG L P P P
Sbjct: 672 GPESATPAPGALDPGPSP 689
Score = 76.6 bits (187), Expect = 1e-13
Identities = 116/470 (24%), Positives = 152/470 (32%), Gaps = 126/470 (26%)
Query: 469 PADALKLRSPRGSPDGSLQ------TGKPSAPKKLKLDVGEAMAPPSHRKGDSNANSDVC 522
PA + + R P P S+ T +PS + + G + P+ R S+A
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242
Query: 523 AAALRGLSRTILMCGPLIKEETHRRLHDLVLPLVMGVQQGEVLGSSPYTSSRCRRELYCL 582
A +R + + L L P V ++ P +SS
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-------- 294
Query: 583 LLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVP--PLQP 640
L PSP PP + +L + + S T A TH +P PL P
Sbjct: 295 ----LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA-THSFLPSPPLSP 349
Query: 641 MGPTCPTPAPVPPPEAPSPFRAPPFH-PPGPMPSVGSMPSAGPMPSA------------- 686
+ PPP+AP PP PP P S P A P P A
Sbjct: 350 LA--------TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401
Query: 687 GPMPSAGPV-----PSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILA 741
P PS PV P A P +A + P L + P ++ P P P ++
Sbjct: 402 SPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-------ASPPMS 453
Query: 742 PSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL--- 798
PS TPPP PP P PPL
Sbjct: 454 PSATPPPQAPP---------------------------------------PLAAPPLQLA 474
Query: 799 -PPP--PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPP--------- 846
PPP PP+ ATPP A PP + P LP +P PPP PP
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534
Query: 847 ---------------PPVPGPVT-LPPPQLVPEGTPGGGGPPALEEDLTV 880
PP PGP T + P+L PG PP+ T+
Sbjct: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584
Score = 50.8 bits (120), Expect = 7e-06
Identities = 84/318 (26%), Positives = 106/318 (33%), Gaps = 46/318 (14%)
Query: 591 SPRCPPPLACA----LQAFSLGQREDSLEVSSFCSEALVTCAAL----THPRVPPLQPMG 642
SPR PPP+ A L A R+ E + A + +A T PP G
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRG 91
Query: 643 PTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAG-----PMPSAGPVPS 697
P P SP RA PGP+ G SA + G P SA +
Sbjct: 92 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151
Query: 698 AR------PGPPTTA---------NHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP 742
R PG P+ A +GL P + P GP + ++E P
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211
Query: 743 SGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPP 802
S P + GG + RPA +S +S + S S P P
Sbjct: 212 S----PAARRRPSAGGGLQRPASRSLS---SSATPLSSPARSGPSARGTPRA-----PAH 259
Query: 803 PSGATPPPIAPTGPPTASPP----VPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP-P 857
PS P + PP +PP PA P A PP P P P TLP P
Sbjct: 260 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP-PSLQTLPSP 318
Query: 858 PQLVPEGTPGGGGPPALE 875
P P G P L+
Sbjct: 319 PATPPSQATTSLGSPTLQ 336
Score = 47.0 bits (110), Expect = 1e-04
Identities = 42/161 (26%), Positives = 57/161 (35%), Gaps = 29/161 (18%)
Query: 976 APP--PPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA----PE 1029
+PP PP P A PPP++PP + P L++ +P + T P A P
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPP-------LQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089
+ P Q SP+A P L P APP L + +Q PP PA ++
Sbjct: 498 SFPGQAPF-----SPSASLPMSPLATPPPQAPPVL-------AAPLLQVPPSPPASPTLQ 545
Query: 1090 TETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
+ PP PPP P S
Sbjct: 546 APRRPPTPGPDTSVSGPRLTLALAPGPP----PPPSRSPSS 582
Score = 45.1 bits (105), Expect = 4e-04
Identities = 81/340 (23%), Positives = 95/340 (27%), Gaps = 108/340 (31%)
Query: 643 PTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAG------PMPSAGPVP 696
P TP P P P P G +VG P A G P AGP
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 697 SARP---GPPTTANHLGLSVPGLVSVPPR----LLPGPENHR------------------ 731
++RP G A + PG VS P R PGP +
Sbjct: 82 TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141
Query: 732 -------AGSNEDPILAPSGTPPPTIPPDETFGGR---VPRPAFVHYDKEEASDVEISLE 781
AG+ D GTP P + G +PRPA + S+
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 201
Query: 782 SDSDDSVV---------------------------IVPEGLP----------PLPPPPPS 804
S S+ S P P P P PS
Sbjct: 202 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 261
Query: 805 GATPPPIAPTGPPTASPP----VPAKEEPEELP-AAPGPLPPPPPPPPP----VPGPVTL 855
P + PP +PP PA P A P P PP P PP +P P
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321
Query: 856 PP---------------------PQLVPEGTPGGGGPPAL 874
PP P L P TP PPAL
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 977 PPPPTLPPALPPPESPP-------KVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
P PP P A PPP++PP + P P P L + P + AP
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP-LSPLATPSPQAPNALAVHLLQAPF 401
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM 1088
+ P V+ SP A PP APP+L + +Q PP PA M
Sbjct: 402 SPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSL-------AAPPLQVPPSPPASPPM 452
Score = 39.7 bits (91), Expect = 0.016
Identities = 38/160 (23%), Positives = 48/160 (30%), Gaps = 18/160 (11%)
Query: 976 APPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQG 1035
APP P+ PP+L SPP P + P + +P L+P A P
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356
Query: 1036 EVE-------REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM 1088
+ SP A PP L P AP L + PPP P +
Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ---APFSPPPSPPVQAPF 413
Query: 1089 ETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
A + PP P PP P
Sbjct: 414 SPPASPPVSPSATPPSQA---PPSLAAPPLQVPPSPPASP 450
Score = 35.4 bits (80), Expect = 0.31
Identities = 27/103 (26%), Positives = 35/103 (33%), Gaps = 14/103 (13%)
Query: 976 APPPPTLPPALP---------PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL 1026
A P P P AL PP SPP P P + P ++ P
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 1027 APEALPSQGEVEREGESPAAGP-----PPQELVEEEPSAPPTL 1064
P + P+ + P P PP +L + P APP L
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484
Score = 35.0 bits (79), Expect = 0.40
Identities = 41/175 (23%), Positives = 57/175 (32%), Gaps = 44/175 (25%)
Query: 977 PPPPTLPPA-----------------LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERG 1019
P PP PP+ LP P P P P+ P L L P +
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL----PPLQAPPS 371
Query: 1020 ADTAPTLAPEALPSQGEVEREG----ESPAAGP--PPQELVEEEPSAPPTLLEEETEDGS 1073
+P L+P A PS ++P + P PP + P++PP S
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV---------S 422
Query: 1074 DKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
PP + P A LQ + ++ PP + PPP P
Sbjct: 423 PSATPPSQAP------PSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAP 469
Score = 32.7 bits (73), Expect = 2.0
Identities = 32/130 (24%), Positives = 38/130 (29%), Gaps = 18/130 (13%)
Query: 966 GTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT 1025
GT P P L PP +PP+ P P + P P+
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS 311
Query: 1026 L-----APEALPSQGEVE------REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074
L P PSQ + S PP L P APP L
Sbjct: 312 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL-------ALP 364
Query: 1075 KVQPPPETPA 1084
+Q PP PA
Sbjct: 365 PLQAPPSPPA 374
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 86.3 bits (212), Expect = 2e-16
Identities = 99/382 (25%), Positives = 143/382 (37%), Gaps = 62/382 (16%)
Query: 647 TPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTA 706
T +P ++ + PP P P P+ +MP P P+ P+P P P A PP +
Sbjct: 342 TSLQLPASQSALQSQQPPREQPLP-PAPLAMPHIKPPPTT-PIPQL-PAPQAHKHPPHLS 398
Query: 707 NHLGLSVPGLVSVPPRLLPGPE---NHRAGSNEDPI-LAPSGTPPPTIP---PDETFGGR 759
S+ + PP L P +H ++ P+ L P P P+ P P T
Sbjct: 399 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 458
Query: 760 VPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPP-PSGATPP--PIAPTGP 816
+P P H + + VP G PP+ PP PS +TPP P P
Sbjct: 459 LPPPPASH----PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
Query: 817 PTA-------------SPPVPAKEEPEE-LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVP 862
P + S P+P + EE L A P PPPPP P P P + P
Sbjct: 515 PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHAS 574
Query: 863 EGTP-----GGGGPPALEEDLTVININSSD----EEEEEEEEEEEEEEEEEEEEEDFEEE 913
+ G DL + + S EE E+ + E E++ EE E +E+
Sbjct: 575 QSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEK 634
Query: 914 EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973
E++ E E E E E + EG L + + + G +
Sbjct: 635 EKEREREREREREAERAAKASSSAHEGRLSDPQL-------------------SGPGHMR 675
Query: 974 EGAPPPPTLPPALPP---PESP 992
PPPT A+PP P++P
Sbjct: 676 PSFEPPPTTIAAVPPYIGPDTP 697
Score = 80.5 bits (197), Expect = 8e-15
Identities = 118/468 (25%), Positives = 155/468 (33%), Gaps = 101/468 (21%)
Query: 634 RVPPLQPMGPTCPTPAPVPPPEAP------------SPFRA-PPFHPPGPMPSVGSMPSA 680
+ P L P P P P P P P P +P A PP H GP P S+ +
Sbjct: 248 QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAG 306
Query: 681 GPMPSAGPMPSAGPVPSARPG-------PPTTANHLGLSVPGLVSV-----PPRLLPGPE 728
+ GP G P A G P H L +P S PPR P P
Sbjct: 307 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366
Query: 729 NHRAGSNEDPILAPSGTPPPTIPPDET------FGGRVPRPAFVHYDKEEASDVEISLES 782
A + P P TP P +P + G P + A SL +
Sbjct: 367 APLAMPHIKP---PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST 423
Query: 783 DSDDS-----VVIVPEGLP-PLPPPPPSGAT-----PPPIA---PTGPPTASPPVPAKEE 828
S + ++P+ P P P P G T PPP A PTG +P P +
Sbjct: 424 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 483
Query: 829 PEELPAAPGPLPPPPPP----PPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININ 884
P +P P P+ PP P PP PG PP G GG A + +
Sbjct: 484 PF-VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS----GAAASGGSIAGGSSCPLPTVQ 538
Query: 885 SSDEEEEEEEEEEE-----EEEEEEEEEEDFEEEEEDEEEYFE----------------- 922
+E ++ EE E E D +++
Sbjct: 539 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM 598
Query: 923 ---------EEEEEEEEFEEEFEE---EEGELEEEEEEEDEEEEEELEEVEDLEFGTAGG 970
+ EE E+ + E E+ EE E E+E+E+E E E E E E A
Sbjct: 599 PLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAE--RAAKASS 656
Query: 971 EVEEGAPPPPTL-------PPALPPPESPPKVQPEPEPEPGLLLEVEE 1011
EG P L P PPP + V P P+ L + E
Sbjct: 657 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSE 704
Score = 77.8 bits (190), Expect = 5e-14
Identities = 83/269 (30%), Positives = 111/269 (41%), Gaps = 53/269 (19%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAP--PFHPPGPMP--SVGSMPSAGPM--PSA 686
P P L GPT P+ VPP +P+ +AP P P P+P + P+ P PS
Sbjct: 202 PGTPQLPTPGPT-PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 260
Query: 687 GPMPSAGPVPSARP-----GPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILA 741
P P P P +P G P+ +H + P L P PGP + +AG P+L
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSH---AQPPLHGQGP---PGPHSLQAG----PLLQ 310
Query: 742 PSGTPPP-TIPPDETFG----GRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLP 796
G P P +PP + G G P A+ H + + + +L+S P
Sbjct: 311 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS-QSALQSQQ-------PPREQ 362
Query: 797 PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLP-------PPPPPPPPV 849
PLPP P P I P P T P +PA + + P GP P PPPP P+
Sbjct: 363 PLPPAP---LAMPHIKPP-PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL 418
Query: 850 PG------PVTLPPP-QLVPEGTPGGGGP 871
P PPP QL+P+ P P
Sbjct: 419 SSLSTHHPPSAHPPPLQLMPQSQPLPSSP 447
Score = 43.5 bits (101), Expect = 0.001
Identities = 36/118 (30%), Positives = 40/118 (33%), Gaps = 27/118 (22%)
Query: 781 ESDSDDSV-----------VIVPEGLPPLPPPPPSGAT------PPPIAPTGPPTASPPV 823
ESDSD S + P G+ P P P G P P A PP SP
Sbjct: 168 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 227
Query: 824 PAKEEPEELPAAP--------GPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
+ P AP P P PP P P P P P L P G G P+
Sbjct: 228 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP--LTGSAGQPS 283
Score = 36.2 bits (82), Expect = 0.18
Identities = 36/191 (18%), Positives = 66/191 (34%), Gaps = 20/191 (10%)
Query: 885 SSDEEEEEEEEEEEEEEEE---EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941
+SD EE + ++ + +E + E E D +E + ++ +++
Sbjct: 101 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS 160
Query: 942 LEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP 1001
+ ++ E + + +++ + AP T P+ PP +P P P P
Sbjct: 161 IPSPQDNESDSDSSAQQQMLQAQPPALQ------APTGVTPAPSSAPPGTPQLPTPGPTP 214
Query: 1002 EPGLLLEVEEPGTEEERGADTAPTL---------APEALPSQGEVEREGESPAAGPPPQE 1052
+ P + APT AP P + P+ PP Q
Sbjct: 215 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 274
Query: 1053 LVEE--EPSAP 1061
L +PSAP
Sbjct: 275 LTGSAGQPSAP 285
Score = 35.8 bits (81), Expect = 0.24
Identities = 33/178 (18%), Positives = 68/178 (38%), Gaps = 13/178 (7%)
Query: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
+EE + + + E+ + EE + ++ + +E E EGE + DE
Sbjct: 83 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 142
Query: 952 EEEEELEEVEDLEFGTAG------GEVEEGAPPPPTLPPALPPP-ESPPKVQPEPEPEPG 1004
+ + +D + E + + + A PP ++P V P P P
Sbjct: 143 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP 202
Query: 1005 LLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPP 1062
++ PG +A + P+ P+ + + ++P A P P +++ P+ P
Sbjct: 203 GTPQLPTPGP-----TPSATAVPPQGSPTASQAPNQPQAPTA-PVPHTHIQQAPALHP 254
Score = 35.8 bits (81), Expect = 0.24
Identities = 38/166 (22%), Positives = 58/166 (34%), Gaps = 44/166 (26%)
Query: 977 PPPPTLPPAL------PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERG-----ADTAPT 1025
PPPP L P PP PP +Q P+ +P + PG + + A PT
Sbjct: 410 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469
Query: 1026 LAPEALPSQGEVER---EGESPAAGPPPQELVEEEPSAP--------------------- 1061
+ P + G P PP P+ P
Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 529
Query: 1062 -----PTL-LEEETEDGSDKVQ---PPPETPAEEEMETETEAEALQ 1098
PT+ ++EE D +++ + PPP +P+ E +T + A Q
Sbjct: 530 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQ 575
Score = 34.7 bits (78), Expect = 0.53
Identities = 34/151 (22%), Positives = 53/151 (35%), Gaps = 15/151 (9%)
Query: 724 LPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD 783
+P P+++ + S+ PP + G P P+ ++
Sbjct: 161 IPSPQDNESDSDSSAQQQMLQAQPPALQAPT---GVTPAPS-----SAPPGTPQLPTPGP 212
Query: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPP 843
+ + + P+G P S A P APT P + A + P +P P P P
Sbjct: 213 TPSATAVPPQGSPT-----ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 267
Query: 844 PPPP--PVPGPVTLPPPQLVPEGTPGGGGPP 872
P PP P+ G P + G GPP
Sbjct: 268 PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298
Score = 31.2 bits (69), Expect = 5.8
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 11/111 (9%)
Query: 973 EEGAPPPPTLPPALPPPESPPKVQ---PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
E+ PP P P + PP + P Q P+ P L + A+ P A +
Sbjct: 361 EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL----SGPSPFSMNANLPPPPALK 416
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
L S P+A PPP +L+ + P + + S + PPP
Sbjct: 417 PLSSLST----HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 86.3 bits (212), Expect = 2e-16
Identities = 99/382 (25%), Positives = 143/382 (37%), Gaps = 62/382 (16%)
Query: 647 TPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTA 706
T +P ++ + PP P P P+ +MP P P+ P+P P P A PP +
Sbjct: 896 TSLQLPASQSALQSQQPPREQPLP-PAPLAMPHIKPPPTT-PIPQL-PAPQAHKHPPHLS 952
Query: 707 NHLGLSVPGLVSVPPRLLPGPE---NHRAGSNEDPI-LAPSGTPPPTIP---PDETFGGR 759
S+ + PP L P +H ++ P+ L P P P+ P P T
Sbjct: 953 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 760 VPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPP-PSGATPP--PIAPTGP 816
+P P H + + VP G PP+ PP PS +TPP P P
Sbjct: 1013 LPPPPASH----PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Query: 817 PTA-------------SPPVPAKEEPEE-LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVP 862
P + S P+P + EE L A P PPPPP P P P + P
Sbjct: 1069 PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHAS 1128
Query: 863 EGTP-----GGGGPPALEEDLTVININSSD----EEEEEEEEEEEEEEEEEEEEEDFEEE 913
+ G DL + + S EE E+ + E E++ EE E +E+
Sbjct: 1129 QSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEK 1188
Query: 914 EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973
E++ E E E E E + EG L + + + G +
Sbjct: 1189 EKEREREREREREAERAAKASSSAHEGRLSDPQL-------------------SGPGHMR 1229
Query: 974 EGAPPPPTLPPALPP---PESP 992
PPPT A+PP P++P
Sbjct: 1230 PSFEPPPTTIAAVPPYIGPDTP 1251
Score = 80.5 bits (197), Expect = 8e-15
Identities = 118/468 (25%), Positives = 155/468 (33%), Gaps = 101/468 (21%)
Query: 634 RVPPLQPMGPTCPTPAPVPPPEAP------------SPFRA-PPFHPPGPMPSVGSMPSA 680
+ P L P P P P P P P P +P A PP H GP P S+ +
Sbjct: 802 QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAG 860
Query: 681 GPMPSAGPMPSAGPVPSARPG-------PPTTANHLGLSVPGLVSV-----PPRLLPGPE 728
+ GP G P A G P H L +P S PPR P P
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
Query: 729 NHRAGSNEDPILAPSGTPPPTIPPDET------FGGRVPRPAFVHYDKEEASDVEISLES 782
A + P P TP P +P + G P + A SL +
Sbjct: 921 APLAMPHIKP---PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST 977
Query: 783 DSDDS-----VVIVPEGLP-PLPPPPPSGAT-----PPPIA---PTGPPTASPPVPAKEE 828
S + ++P+ P P P P G T PPP A PTG +P P +
Sbjct: 978 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 1037
Query: 829 PEELPAAPGPLPPPPPP----PPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININ 884
P +P P P+ PP P PP PG PP G GG A + +
Sbjct: 1038 PF-VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS----GAAASGGSIAGGSSCPLPTVQ 1092
Query: 885 SSDEEEEEEEEEEE-----EEEEEEEEEEDFEEEEEDEEEYFE----------------- 922
+E ++ EE E E D +++
Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM 1152
Query: 923 ---------EEEEEEEEFEEEFEE---EEGELEEEEEEEDEEEEEELEEVEDLEFGTAGG 970
+ EE E+ + E E+ EE E E+E+E+E E E E E E A
Sbjct: 1153 PLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAE--RAAKASS 1210
Query: 971 EVEEGAPPPPTL-------PPALPPPESPPKVQPEPEPEPGLLLEVEE 1011
EG P L P PPP + V P P+ L + E
Sbjct: 1211 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSE 1258
Score = 77.8 bits (190), Expect = 5e-14
Identities = 83/269 (30%), Positives = 111/269 (41%), Gaps = 53/269 (19%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAP--PFHPPGPMP--SVGSMPSAGPM--PSA 686
P P L GPT P+ VPP +P+ +AP P P P+P + P+ P PS
Sbjct: 756 PGTPQLPTPGPT-PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 814
Query: 687 GPMPSAGPVPSARP-----GPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILA 741
P P P P +P G P+ +H + P L P PGP + +AG P+L
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSH---AQPPLHGQGP---PGPHSLQAG----PLLQ 864
Query: 742 PSGTPPP-TIPPDETFG----GRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLP 796
G P P +PP + G G P A+ H + + + +L+S P
Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS-QSALQSQQ-------PPREQ 916
Query: 797 PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLP-------PPPPPPPPV 849
PLPP P P I P P T P +PA + + P GP P PPPP P+
Sbjct: 917 PLPPAP---LAMPHIKPP-PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL 972
Query: 850 PG------PVTLPPP-QLVPEGTPGGGGP 871
P PPP QL+P+ P P
Sbjct: 973 SSLSTHHPPSAHPPPLQLMPQSQPLPSSP 1001
Score = 43.5 bits (101), Expect = 0.001
Identities = 36/118 (30%), Positives = 40/118 (33%), Gaps = 27/118 (22%)
Query: 781 ESDSDDSV-----------VIVPEGLPPLPPPPPSGAT------PPPIAPTGPPTASPPV 823
ESDSD S + P G+ P P P G P P A PP SP
Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 781
Query: 824 PAKEEPEELPAAP--------GPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
+ P AP P P PP P P P P P L P G G P+
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP--LTGSAGQPS 837
Score = 37.0 bits (84), Expect = 0.11
Identities = 52/275 (18%), Positives = 96/275 (34%), Gaps = 50/275 (18%)
Query: 831 ELPAAPGPLPPPPPPPPPVP-------------------GPVTLPPPQLVPEGTPGGGGP 871
ELP P+ PPP PV TL + +P G
Sbjct: 541 ELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600
Query: 872 PALEEDLTVININS------SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925
P + ED+ NS S + + E ++ ++ +EE + + E+ + E
Sbjct: 601 P-INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTE 659
Query: 926 EEEEEFEEEFE-----------EEEGELEEEEEEEDEEEEEELEEVEDLEFGTAG----- 969
E + ++ + E EGE + DE + + +D +
Sbjct: 660 EADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQ 719
Query: 970 -GEVEEGAPPPPTLPPALPPP-ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA 1027
E + + + A PP ++P V P P P ++ PG +A +
Sbjct: 720 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP 774
Query: 1028 PEALPSQGEVEREGESPAAGPPPQELVEEEPSAPP 1062
P+ P+ + + ++P A P P +++ P+ P
Sbjct: 775 PQGSPTASQAPNQPQAPTA-PVPHTHIQQAPALHP 808
Score = 36.2 bits (82), Expect = 0.18
Identities = 36/191 (18%), Positives = 66/191 (34%), Gaps = 20/191 (10%)
Query: 885 SSDEEEEEEEEEEEEEEEE---EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941
+SD EE + ++ + +E + E E D +E + ++ +++
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS 714
Query: 942 LEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP 1001
+ ++ E + + +++ + AP T P+ PP +P P P P
Sbjct: 715 IPSPQDNESDSDSSAQQQMLQAQPPALQ------APTGVTPAPSSAPPGTPQLPTPGPTP 768
Query: 1002 EPGLLLEVEEPGTEEERGADTAPTL---------APEALPSQGEVEREGESPAAGPPPQE 1052
+ P + APT AP P + P+ PP Q
Sbjct: 769 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 1053 LVEE--EPSAP 1061
L +PSAP
Sbjct: 829 LTGSAGQPSAP 839
Score = 35.8 bits (81), Expect = 0.24
Identities = 38/166 (22%), Positives = 58/166 (34%), Gaps = 44/166 (26%)
Query: 977 PPPPTLPPAL------PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERG-----ADTAPT 1025
PPPP L P PP PP +Q P+ +P + PG + + A PT
Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 1026 LAPEALPSQGEVER---EGESPAAGPPPQELVEEEPSAP--------------------- 1061
+ P + G P PP P+ P
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 1062 -----PTL-LEEETEDGSDKVQ---PPPETPAEEEMETETEAEALQ 1098
PT+ ++EE D +++ + PPP +P+ E +T + A Q
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQ 1129
Score = 34.7 bits (78), Expect = 0.53
Identities = 34/151 (22%), Positives = 53/151 (35%), Gaps = 15/151 (9%)
Query: 724 LPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD 783
+P P+++ + S+ PP + G P P+ ++
Sbjct: 715 IPSPQDNESDSDSSAQQQMLQAQPPALQAPT---GVTPAPS-----SAPPGTPQLPTPGP 766
Query: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPP 843
+ + + P+G P S A P APT P + A + P +P P P P
Sbjct: 767 TPSATAVPPQGSPT-----ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821
Query: 844 PPPP--PVPGPVTLPPPQLVPEGTPGGGGPP 872
P PP P+ G P + G GPP
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Score = 31.2 bits (69), Expect = 5.8
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 11/111 (9%)
Query: 973 EEGAPPPPTLPPALPPPESPPKVQ---PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
E+ PP P P + PP + P Q P+ P L + A+ P A +
Sbjct: 915 EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL----SGPSPFSMNANLPPPPALK 970
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
L S P+A PPP +L+ + P + + S + PPP
Sbjct: 971 PLSSLST----HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 86.3 bits (212), Expect = 2e-16
Identities = 99/382 (25%), Positives = 143/382 (37%), Gaps = 62/382 (16%)
Query: 647 TPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTA 706
T +P ++ + PP P P P+ +MP P P+ P+P P P A PP +
Sbjct: 896 TSLQLPASQSALQSQQPPREQPLP-PAPLAMPHIKPPPTT-PIPQL-PAPQAHKHPPHLS 952
Query: 707 NHLGLSVPGLVSVPPRLLPGPE---NHRAGSNEDPI-LAPSGTPPPTIP---PDETFGGR 759
S+ + PP L P +H ++ P+ L P P P+ P P T
Sbjct: 953 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 760 VPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPP-PSGATPP--PIAPTGP 816
+P P H + + VP G PP+ PP PS +TPP P P
Sbjct: 1013 LPPPPASH----PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Query: 817 PTA-------------SPPVPAKEEPEE-LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVP 862
P + S P+P + EE L A P PPPPP P P P + P
Sbjct: 1069 PCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHAS 1128
Query: 863 EGTP-----GGGGPPALEEDLTVININSSD----EEEEEEEEEEEEEEEEEEEEEDFEEE 913
+ G DL + + S EE E+ + E E++ EE E +E+
Sbjct: 1129 QSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEK 1188
Query: 914 EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973
E++ E E E E E + EG L + + + G +
Sbjct: 1189 EKEREREREREREAERAAKASSSAHEGRLSDPQL-------------------SGPGHMR 1229
Query: 974 EGAPPPPTLPPALPP---PESP 992
PPPT A+PP P++P
Sbjct: 1230 PSFEPPPTTIAAVPPYIGPDTP 1251
Score = 80.5 bits (197), Expect = 8e-15
Identities = 118/468 (25%), Positives = 155/468 (33%), Gaps = 101/468 (21%)
Query: 634 RVPPLQPMGPTCPTPAPVPPPEAP------------SPFRA-PPFHPPGPMPSVGSMPSA 680
+ P L P P P P P P P P +P A PP H GP P S+ +
Sbjct: 802 QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAG 860
Query: 681 GPMPSAGPMPSAGPVPSARPG-------PPTTANHLGLSVPGLVSV-----PPRLLPGPE 728
+ GP G P A G P H L +P S PPR P P
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
Query: 729 NHRAGSNEDPILAPSGTPPPTIPPDET------FGGRVPRPAFVHYDKEEASDVEISLES 782
A + P P TP P +P + G P + A SL +
Sbjct: 921 APLAMPHIKP---PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST 977
Query: 783 DSDDS-----VVIVPEGLP-PLPPPPPSGAT-----PPPIA---PTGPPTASPPVPAKEE 828
S + ++P+ P P P P G T PPP A PTG +P P +
Sbjct: 978 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 1037
Query: 829 PEELPAAPGPLPPPPPP----PPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININ 884
P +P P P+ PP P PP PG PP G GG A + +
Sbjct: 1038 PF-VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCS----GAAASGGSIAGGSSCPLPTVQ 1092
Query: 885 SSDEEEEEEEEEEE-----EEEEEEEEEEDFEEEEEDEEEYFE----------------- 922
+E ++ EE E E D +++
Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM 1152
Query: 923 ---------EEEEEEEEFEEEFEE---EEGELEEEEEEEDEEEEEELEEVEDLEFGTAGG 970
+ EE E+ + E E+ EE E E+E+E+E E E E E E A
Sbjct: 1153 PLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAE--RAAKASS 1210
Query: 971 EVEEGAPPPPTL-------PPALPPPESPPKVQPEPEPEPGLLLEVEE 1011
EG P L P PPP + V P P+ L + E
Sbjct: 1211 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSE 1258
Score = 77.8 bits (190), Expect = 5e-14
Identities = 83/269 (30%), Positives = 111/269 (41%), Gaps = 53/269 (19%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAP--PFHPPGPMP--SVGSMPSAGPM--PSA 686
P P L GPT P+ VPP +P+ +AP P P P+P + P+ P PS
Sbjct: 756 PGTPQLPTPGPT-PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 814
Query: 687 GPMPSAGPVPSARP-----GPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILA 741
P P P P +P G P+ +H + P L P PGP + +AG P+L
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSH---AQPPLHGQGP---PGPHSLQAG----PLLQ 864
Query: 742 PSGTPPP-TIPPDETFG----GRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLP 796
G P P +PP + G G P A+ H + + + +L+S P
Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS-QSALQSQQ-------PPREQ 916
Query: 797 PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLP-------PPPPPPPPV 849
PLPP P P I P P T P +PA + + P GP P PPPP P+
Sbjct: 917 PLPPAP---LAMPHIKPP-PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL 972
Query: 850 PG------PVTLPPP-QLVPEGTPGGGGP 871
P PPP QL+P+ P P
Sbjct: 973 SSLSTHHPPSAHPPPLQLMPQSQPLPSSP 1001
Score = 43.5 bits (101), Expect = 0.001
Identities = 36/118 (30%), Positives = 40/118 (33%), Gaps = 27/118 (22%)
Query: 781 ESDSDDSV-----------VIVPEGLPPLPPPPPSGAT------PPPIAPTGPPTASPPV 823
ESDSD S + P G+ P P P G P P A PP SP
Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 781
Query: 824 PAKEEPEELPAAP--------GPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
+ P AP P P PP P P P P P L P G G P+
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP--LTGSAGQPS 837
Score = 37.0 bits (84), Expect = 0.11
Identities = 52/275 (18%), Positives = 96/275 (34%), Gaps = 50/275 (18%)
Query: 831 ELPAAPGPLPPPPPPPPPVP-------------------GPVTLPPPQLVPEGTPGGGGP 871
ELP P+ PPP PV TL + +P G
Sbjct: 541 ELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600
Query: 872 PALEEDLTVININS------SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925
P + ED+ NS S + + E ++ ++ +EE + + E+ + E
Sbjct: 601 P-INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTE 659
Query: 926 EEEEEFEEEFE-----------EEEGELEEEEEEEDEEEEEELEEVEDLEFGTAG----- 969
E + ++ + E EGE + DE + + +D +
Sbjct: 660 EADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQ 719
Query: 970 -GEVEEGAPPPPTLPPALPPP-ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA 1027
E + + + A PP ++P V P P P ++ PG +A +
Sbjct: 720 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP 774
Query: 1028 PEALPSQGEVEREGESPAAGPPPQELVEEEPSAPP 1062
P+ P+ + + ++P A P P +++ P+ P
Sbjct: 775 PQGSPTASQAPNQPQAPTA-PVPHTHIQQAPALHP 808
Score = 36.2 bits (82), Expect = 0.18
Identities = 36/191 (18%), Positives = 66/191 (34%), Gaps = 20/191 (10%)
Query: 885 SSDEEEEEEEEEEEEEEEE---EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941
+SD EE + ++ + +E + E E D +E + ++ +++
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS 714
Query: 942 LEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP 1001
+ ++ E + + +++ + AP T P+ PP +P P P P
Sbjct: 715 IPSPQDNESDSDSSAQQQMLQAQPPALQ------APTGVTPAPSSAPPGTPQLPTPGPTP 768
Query: 1002 EPGLLLEVEEPGTEEERGADTAPTL---------APEALPSQGEVEREGESPAAGPPPQE 1052
+ P + APT AP P + P+ PP Q
Sbjct: 769 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP 828
Query: 1053 LVEE--EPSAP 1061
L +PSAP
Sbjct: 829 LTGSAGQPSAP 839
Score = 35.8 bits (81), Expect = 0.24
Identities = 38/166 (22%), Positives = 58/166 (34%), Gaps = 44/166 (26%)
Query: 977 PPPPTLPPAL------PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERG-----ADTAPT 1025
PPPP L P PP PP +Q P+ +P + PG + + A PT
Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 1026 LAPEALPSQGEVER---EGESPAAGPPPQELVEEEPSAP--------------------- 1061
+ P + G P PP P+ P
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 1062 -----PTL-LEEETEDGSDKVQ---PPPETPAEEEMETETEAEALQ 1098
PT+ ++EE D +++ + PPP +P+ E +T + A Q
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQ 1129
Score = 34.7 bits (78), Expect = 0.53
Identities = 34/151 (22%), Positives = 53/151 (35%), Gaps = 15/151 (9%)
Query: 724 LPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD 783
+P P+++ + S+ PP + G P P+ ++
Sbjct: 715 IPSPQDNESDSDSSAQQQMLQAQPPALQAPT---GVTPAPS-----SAPPGTPQLPTPGP 766
Query: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPP 843
+ + + P+G P S A P APT P + A + P +P P P P
Sbjct: 767 TPSATAVPPQGSPT-----ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821
Query: 844 PPPP--PVPGPVTLPPPQLVPEGTPGGGGPP 872
P PP P+ G P + G GPP
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Score = 31.2 bits (69), Expect = 5.8
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 11/111 (9%)
Query: 973 EEGAPPPPTLPPALPPPESPPKVQ---PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE 1029
E+ PP P P + PP + P Q P+ P L + A+ P A +
Sbjct: 915 EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL----SGPSPFSMNANLPPPPALK 970
Query: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
L S P+A PPP +L+ + P + + S + PPP
Sbjct: 971 PLSSLST----HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 85.9 bits (211), Expect = 2e-16
Identities = 134/463 (28%), Positives = 161/463 (34%), Gaps = 90/463 (19%)
Query: 467 SPP-ADALKLRSPRGSPDGSLQTGKPSAPKKLKLDVGEAM------APPS---------- 509
SPP A L L P S SLQT PS P +M APPS
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQT-LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 510 HRKGDSNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHDLVLPLVMGVQQGEVLGSSP 569
H + + AL L T + P + + TH L + S+P
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTL-QATHSFLTMSPRQTQASLTSPSRPASTP 451
Query: 570 YTSSRCRRELYC-----LLLALLLAPSPRCPPPLACALQAFS-LGQREDSLEVSSFCSEA 623
S + L L +L A SP P LQA S L +SS
Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP 511
Query: 624 LVTCAALTHP--RVPPLQPMGP---TCPTPAPVPPPEAPSPFRAPPFH-PPGPMPSVGSM 677
L T ++L P + PP P P+ AP P A +P P PP P P
Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571
Query: 678 PSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737
P P P P P PS+ PP A P L S P + LP P
Sbjct: 572 P---PSPLTTPPPET---PSSIATPPPQAP------PALASPPLQGLPSPP--------- 610
Query: 738 PILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPP 797
L+P TPPP PP + P AS L + S + + L
Sbjct: 611 --LSPLATPPPQAPPX------LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662
Query: 798 LP-PPPPSGATPPPIAPTGPPTASPPV-----PAKEEPEELPAAPGPLPPPPP------- 844
P PPPS PP AP PP ASPPV P + P L A P +PP PP
Sbjct: 663 APFSPPPS---PPVQAPFSPP-ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 845 ---PPPPVPGPVTLPP----------PQLVPEGTPGGGGPPAL 874
PPP P P+ PP P + P TP PP L
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL 761
Score = 85.9 bits (211), Expect = 2e-16
Identities = 88/307 (28%), Positives = 112/307 (36%), Gaps = 67/307 (21%)
Query: 584 LALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQ--PM 641
LA+ L +P PPP FS ++ S+A + AA PPLQ P
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA------PPLQVPPS 709
Query: 642 GPTCP--TPAPVPPPEAPSPFRAPPFH-PPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSA 698
P P +P+ PPP+AP P APP PP P S PSA P P P+ +A P+
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL-QV 768
Query: 699 RPGPPTTANHLGLSVP------GLVSVPPRLLPGPENHRAGS-----NEDPILAPSGTPP 747
P PP + L+ P L + P + LP P G + ++P TPP
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 748 PTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGAT 807
P PP ++ L +PP PP A+
Sbjct: 829 PQAPP-------------------------------------VLAAPLLQVPPSPP--AS 849
Query: 808 PPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPG 867
P AP PPT P L APGP PPPP TL P L +
Sbjct: 850 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSA 904
Query: 868 GGGPPAL 874
P L
Sbjct: 905 TSTPEEL 911
Score = 84.7 bits (208), Expect = 4e-16
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 74/289 (25%)
Query: 633 PRVPPLQPMGPTCP---------------TPAPVPPPEAP-SPFRAPPFHPPGPMPSVGS 676
P PPL P+ P +P P PP +AP SP +PP P PS
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696
Query: 677 MPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNE 736
A P P P A P S PP A P L + P ++ P P
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAP------PPLAAPPLQVPPSPP-------A 743
Query: 737 DPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLP 796
P ++PS TPPP +PP + + + S+ + P P
Sbjct: 744 SPPMSPSATPPPRVPP-------------------LLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 797 PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPP---------- 846
P P PP+ ATPP A PP + P LP +P PPP PP
Sbjct: 785 P-PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843
Query: 847 --------------PPVPGPVT-LPPPQLVPEGTPGGGGPPALEEDLTV 880
PP PGP T + P+L PG PP+ T+
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
Score = 77.8 bits (190), Expect = 5e-14
Identities = 89/301 (29%), Positives = 102/301 (33%), Gaps = 70/301 (23%)
Query: 590 PSPRCPPPLACALQAFSLGQREDSLEVS-SFCSEALVTCAALTHPRVPPLQPMGPTCPTP 648
P P+ PPPLA L+V S + ++ +A PRVPPL P P
Sbjct: 722 PPPQAPPPLAAP-----------PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 649 APV----------PPPEAPSPFRAPPFHP-PGPMPSVGSMPSAGPMPSAGPMPSAGPVPS 697
+P PPP+AP PP P P S P S P A P P
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 698 ARPGPPTTANHLGLSVPGLVSVPPRL-------LPGPENHRAGSNEDPILAPSGTPPPTI 750
A PP A L L VP P L PGP+ +G LAP PPP+
Sbjct: 831 A---PPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886
Query: 751 PPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPP------- 803
P T G P + S E DS PEG PPP
Sbjct: 887 SPSSTLSG----PDLAGHSSSATSTPEELRGYDSG------PEGGAAASPPPDAELAACH 936
Query: 804 ----SGATPPPIAPTGPPTASPPVPAK---------------EEPEELPAAPGPLPPPPP 844
S PP+A G P A P P E PE APG L P P
Sbjct: 937 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 996
Query: 845 P 845
P
Sbjct: 997 P 997
Score = 68.6 bits (166), Expect = 3e-11
Identities = 102/371 (27%), Positives = 129/371 (34%), Gaps = 104/371 (28%)
Query: 591 SPRCPPPLACA----LQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCP 646
SPR PPP+ A L A R+ E + A + +A PR P + G +
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA---PRAGPTRSAGTSSR 88
Query: 647 TPAPVPPPE-----AP-----------SPFRAPPFHPPGPMPSVGSMPSA---------- 680
PA PP AP SP RA PGP+ G SA
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148
Query: 681 -GPMPSA----------GPMP------------SAG-------PVPSARPGPPTTANHLG 710
P SA GP P +AG P PSARP PPT
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 711 LSVPGLVSVPPRL------------LPGPENHRAGSNEDPILAPS-------GTPPPTIP 751
+S S L P + S+ P+ +P+ GTP
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 752 PDETF--GGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPP 809
P + G + RP V +++A+ L S PL P PSG
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS-------------PLATPSPSGTKAR 315
Query: 810 PIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPP----VPGPVTLPPPQLVPE-G 864
P+ P P A+ P+PA P A P PL PP P PP +P P PP Q P
Sbjct: 316 PVPP--PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT 373
Query: 865 TPGGGGPPALE 875
TP PP+L+
Sbjct: 374 TPPMQAPPSLQ 384
Score = 62.0 bits (149), Expect = 3e-09
Identities = 78/293 (26%), Positives = 103/293 (35%), Gaps = 60/293 (20%)
Query: 629 ALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAP--PFHPPGPM--PSVGSMPS--AGP 682
A P +P+ P P+P PSP A P PP P PS+ ++PS A P
Sbjct: 305 ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 683 MPSAGPMPSAGPV---PSARPGPPTTANH----------------------LGLSVPGLV 717
A P + P+ PS + PP H L P L
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Query: 718 SVPPRLLPGPENHRAG--SNEDPILAPSGTPP-------PTIPPDET----FGGRVPRPA 764
+ L P +A S P P +PP P PP +T + P
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL 484
Query: 765 FVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPP----PPSGATPPPIAPTGPPTAS 820
+H + +S S ++ ++ E L PP PP+ T PP+ P A
Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL-PSLAP 543
Query: 821 PPVPAKEEP-----EELPAAPGPLP---PPPP---PPPPVPGPVTLPPPQLVP 862
PP+ P E P P P P PP P PPP P + PPPQ P
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Score = 61.6 bits (148), Expect = 4e-09
Identities = 68/242 (28%), Positives = 87/242 (35%), Gaps = 50/242 (20%)
Query: 646 PTPAPVPPPEAP--SPFRAPPFHPPGPMPSVGSMPSAGP----------MPSAGPMPS-A 692
P+ P PP E P S A P P+ PSAG SA P+ S A
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 693 GPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP-SGTPPPTIP 751
PSAR P A+ GL ++ P + P A P L P S +P T
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA-----PALGPLSSSPLATPS 308
Query: 752 PDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPP-------PPPS 804
P T VP P D++ +P LPP PP PPS
Sbjct: 309 PSGTKARPVPPP---------------------DNAATPLPATLPPSPPLATPLPLAPPS 347
Query: 805 GATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG 864
+ PP + P A+PP + P + P PP PP+ P +L P L
Sbjct: 348 PSAPPSLQTLPSPPATPP---SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404
Query: 865 TP 866
+P
Sbjct: 405 SP 406
Score = 55.5 bits (132), Expect = 3e-07
Identities = 78/305 (25%), Positives = 105/305 (34%), Gaps = 41/305 (13%)
Query: 589 APSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHP--------------- 633
APS R PP ++ S + E S L P
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 634 -RVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPP--GPMPSVG---SMPSAGPMPS-- 685
R P P P P P+ R P PP P++G S P A P PS
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312
Query: 686 -AGPMP----SAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPIL 740
A P+P +A P+P+ P P A L L+ P S PP L P ++ P
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS-PSAPPSLQTLPSPPATPPSQAP-- 369
Query: 741 APS-GTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVP-----EG 794
PS TPP PP + P + +A ++L S + + P
Sbjct: 370 -PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS 428
Query: 795 LPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVT 854
+ P + P P P SPP+ A P LPA+P P P+ P+T
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQA---PLSLPASPPLQTSLSPAVSPLSSPLT 485
Query: 855 LPPPQ 859
+ P Q
Sbjct: 486 IHPLQ 490
Score = 45.4 bits (106), Expect = 3e-04
Identities = 85/334 (25%), Positives = 101/334 (30%), Gaps = 101/334 (30%)
Query: 643 PTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSA------------GPMPSAGPMP 690
P TP P P P P G +VG P A P AGP
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 691 SAGPV---PSARP---GPPTTANHLGLSVPGLVSVPPR----LLPGPENHR--------- 731
SAG P++RP G A + PG VS P R PGP +
Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141
Query: 732 ----------------AGSNEDPILAPSGTPPPTIPPDETFGGR---VPRPAFVHYDKEE 772
AG+ D GTP P + G +PRPA +
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
Query: 773 ASDVEISLESDSDDSVV----------------------IVPEGLPPLPPPPPSG--ATP 808
S+ S S+ S + PL P SG A
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 809 PPIAPTGPPTASPP-----VPAKEEPEELPAAP--GPL----------------PPPPPP 845
P AP P P P + P AAP GPL P PPP
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 846 PPPVPGPVTLPP-PQL---VPEGTPGGGGPPALE 875
P P TLPP P L +P P PP+L+
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
Score = 44.7 bits (104), Expect = 5e-04
Identities = 41/162 (25%), Positives = 53/162 (32%), Gaps = 27/162 (16%)
Query: 974 EGAPPPPTLPPALPPPESPP-------KVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL 1026
+G P PP P A PPP++PP + P P P L + P +
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP-LSPLATPSPQAPNALAVHLLQ 662
Query: 1027 APEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEE 1086
AP + P V+ SP A PP APP+L + +Q PP PA
Sbjct: 663 APFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSL-------AAPPLQVPPSPPASP 714
Query: 1087 EMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
M + PP P PP P
Sbjct: 715 PMSPSATPPPQAPPP-----------LAAPPLQVPPSPPASP 745
Score = 42.4 bits (98), Expect = 0.003
Identities = 40/142 (28%), Positives = 49/142 (34%), Gaps = 38/142 (26%)
Query: 976 APPPPTLPP--ALPP---PESPPKVQP------------------------EPEPEPGLL 1006
A PPP PP ALPP P SPP P P P P +
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 1007 LEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLE 1066
P + + T P+ AP +L + + SP A PP P APP L
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPL--QVPPSPPASPPMSPSATPPPQAPPPL-- 730
Query: 1067 EETEDGSDKVQPPPETPAEEEM 1088
+ +Q PP PA M
Sbjct: 731 -----AAPPLQVPPSPPASPPM 747
Score = 40.4 bits (93), Expect = 0.010
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 2/88 (2%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PP P P + P +PP P P P L + P + + T P P L +
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA--P 764
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTL 1064
+ SP A P L + P APP L
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Score = 39.7 bits (91), Expect = 0.016
Identities = 45/181 (24%), Positives = 57/181 (31%), Gaps = 42/181 (23%)
Query: 976 APPPPTLPP----------------ALPPPESP-----PKVQPEPEPEPGL-LLEVEEPG 1013
APPP PP A PPP P P +Q P P L + + +P
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 1014 TEEERGADTAPTLA----PEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEET 1069
+ T P A P + P Q SP+A P L P APP L
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPF-----SPSASLPMSPLATPPPQAPPVL----- 835
Query: 1070 EDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPD 1129
+ +Q PP PA ++ + PP PPP P
Sbjct: 836 --AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP----PPPSRSPS 889
Query: 1130 S 1130
S
Sbjct: 890 S 890
Score = 38.9 bits (89), Expect = 0.028
Identities = 40/157 (25%), Positives = 49/157 (31%), Gaps = 11/157 (7%)
Query: 976 APPPPTLPPA---LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
AP P PP+ PPPE+P + P P L G + A T P+A P
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA-TPPPQAPP 623
Query: 1033 SQGEVEREG-ESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETE 1091
+ SP A PP L P AP L + PPP P +
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ---APFSPPPSPPVQAPFSPP 680
Query: 1092 TEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
A + PP P PP P
Sbjct: 681 ASPPVSPSATPPSQA---PPSLAAPPLQVPPSPPASP 714
Score = 37.0 bits (84), Expect = 0.11
Identities = 41/124 (33%), Positives = 44/124 (35%), Gaps = 34/124 (27%)
Query: 977 PPPPTLPPALPPP-------------ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTA 1023
PP LP PPP E+PP P P P L P T T
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA--TP 590
Query: 1024 PTLAPEAL---PSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
P AP AL P QG + SP A PPPQ APP L +Q PP
Sbjct: 591 PPQAPPALASPPLQG-LPSPPLSPLATPPPQ--------APPXL-------ALPPLQAPP 634
Query: 1081 ETPA 1084
PA
Sbjct: 635 SPPA 638
Score = 35.8 bits (81), Expect = 0.24
Identities = 30/115 (26%), Positives = 37/115 (32%), Gaps = 5/115 (4%)
Query: 966 GTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT 1025
GT P P L PP +PP+ P P L T G P
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSGTKARPV 317
Query: 1026 LAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
P+ + P A P P L PSAPP+L + + Q PP
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLP--LAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Score = 33.1 bits (74), Expect = 1.5
Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 5/93 (5%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQG- 1035
P P TLPP+ P P P P P L P T + + T +A PS
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Query: 1036 ----EVEREGESPAAGPPPQELVEEEPSAPPTL 1064
+V SP+ PP L A +L
Sbjct: 386 IPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Score = 32.3 bits (72), Expect = 2.6
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 14/117 (11%)
Query: 976 APPPPTLPPAL---------PPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL 1026
APP P+ PP+L PP ++PP + P P L + P + T+P+L
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTI--PPIQVPHSL-TSPSL 400
Query: 1027 APEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
+A PS + + + G P + + P + S PP++P
Sbjct: 401 --QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Score = 30.4 bits (67), Expect = 9.9
Identities = 36/147 (24%), Positives = 48/147 (32%), Gaps = 7/147 (4%)
Query: 984 PALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGES 1043
PA PP+SPP P P L P T L +AL S +
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL--QALSSLASHSPQAPL 504
Query: 1044 PAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103
+ PP E + APP+L +T S P P+ +T + L +
Sbjct: 505 SSLIMPPLE--TQSSLAPPSL---QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE 559
Query: 1104 DTAAMLADFIDCPPDDEKPPPPTEPDS 1130
+ PP PPP P S
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSS 586
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 85.9 bits (211), Expect = 2e-16
Identities = 86/310 (27%), Positives = 114/310 (36%), Gaps = 75/310 (24%)
Query: 634 RVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPG--PMPSVGSMPSAGPMP------- 684
R+PP +P + P P P P P P ++ P H G P+P PS GP P
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP-HNRGSPPVPGGPRQPSPGPTPPPFPGNR 226
Query: 685 ---------SAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAG-- 733
P+ S+ P + P PPT + L P PP + P HR
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP---PPPPPVGNRPSIHREAVP 283
Query: 734 -----SNEDPI------LAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLES 782
+N+ P+ A S PPP PP +P + + + +SL S
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSS 343
Query: 783 DSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPP 842
+ PPLP P SG PP PP+ PP P ++ P GPLPPP
Sbjct: 344 ST-----------PPLPSPGRSGPLPP------PPSERPPPPVRDP----PGRSGPLPPP 382
Query: 843 PP-----------PPPP-------VPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININ 884
PP P P V P + P P L P+ P G PP ++ N
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPD-RPSAGAPPPPPPSTSIRNGF 441
Query: 885 SSDEEEEEEE 894
E+E E
Sbjct: 442 QDSPCEDEWE 451
Score = 84.7 bits (208), Expect = 4e-16
Identities = 80/274 (29%), Positives = 98/274 (35%), Gaps = 66/274 (24%)
Query: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAP-PFH-----------PPGPMPSVGSMPSAGPM 683
PPL P G + P PP P F P P H P P P VGS P + P
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 684 P---------------SAGPMPSAGPVPSARPGPPTTANHLGLSV-PGLVSVPPRLLPGP 727
P + P+P PS P PP + G ++ G + P P
Sbjct: 186 PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245
Query: 728 ENHRAGSNEDPILAPSGTPPPTIPPDETFGGR-------VPRPAFVHYDKEEASDVEISL 780
++R P A PPP PP G R VP P + S S
Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSA 302
Query: 781 ESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGP--------PTASPPVPAKEEPEEL 832
S + P PPPPPS PPP+ P+ P + + + P
Sbjct: 303 SSQA------------PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Query: 833 PAAPGPLPPPPP--PPPPV------PGPVTLPPP 858
P GPLPPPP PPPPV GP+ PPP
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPP 384
Score = 56.2 bits (134), Expect = 2e-07
Identities = 63/232 (27%), Positives = 79/232 (34%), Gaps = 35/232 (15%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFH------PPGPMPSVGSMPSAGPMPSA 686
P VP + P P PPP P P PP P P ++ S P+PS
Sbjct: 292 PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
Query: 687 GPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPP--------RLLPGPENHRAGSNEDP 738
G P PS RP PP + G S P L PP R LP + S D
Sbjct: 352 GRSGPLPPPPSERP-PPPVRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVD- 408
Query: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798
+P P P +PPD G P P + D E + + P + L
Sbjct: 409 --SPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD--SPCEDEWESRFYFHP--ISDL 462
Query: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVP 850
PPP P T + P+K E + PP PP+P
Sbjct: 463 PPPEPYVQT------------TKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 38.5 bits (88), Expect = 0.036
Identities = 32/102 (31%), Positives = 37/102 (36%), Gaps = 27/102 (26%)
Query: 796 PPLPPP-----------PPSGA----TPPPIAPTGPPTASP---PVPAKEEPEELPAAPG 837
PPL PP PPSG P P +GPP P P + + + P
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 838 PLPPPPPP---------PPPVPGPVTLPPPQLVPEGTPGGGG 870
P+P P P PPVPG P P P PG G
Sbjct: 186 PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG 227
Score = 36.2 bits (82), Expect = 0.18
Identities = 43/166 (25%), Positives = 56/166 (33%), Gaps = 37/166 (22%)
Query: 977 PPPPTLPPALP-----------PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT 1025
PPP P +P PP PP +P P P P +E +R + +
Sbjct: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344
Query: 1026 LAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAE 1085
P LPS G R G P PPP E PP + + G + PPP P
Sbjct: 345 TPP--LPSPG---RSGPLP---PPPSE------RPPPPVRDPPGRSG--PLPPPP--PVS 386
Query: 1086 EEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPP-PPTEPDS 1130
T A + +D P +PP PP P +
Sbjct: 387 RNGSTSRALPATPQLPS-------RSGVDSPRSGPRPPLPPDRPSA 425
Score = 35.8 bits (81), Expect = 0.24
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 10/64 (15%)
Query: 805 GATPPPIAPTGPPTASPPVPAKEEPEELPA-APGPLPPPPPP-----PPPVPG----PVT 854
G+ PP + P G T++ P P P +PG PP P PPP P P +
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS 182
Query: 855 LPPP 858
+PPP
Sbjct: 183 IPPP 186
Score = 35.4 bits (80), Expect = 0.31
Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 25/117 (21%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PPPP+ P P + P + P P P P G+ + A LPS+
Sbjct: 358 PPPPSERPPPPVRDPPGRSGPLPPPPP-----------VSRNGSTSRALPATPQLPSRSG 406
Query: 1037 VEREGESPAAGPPPQELVEEEPSA---PPTLLEEETEDGSDKVQPPPETPAEEEMET 1090
V +SP +GP P L + PSA PP +G ++P E+E E+
Sbjct: 407 V----DSPRSGPRP-PLPPDRPSAGAPPPPPPSTSIRNGFQ------DSPCEDEWES 452
Score = 33.9 bits (76), Expect = 0.90
Identities = 44/190 (23%), Positives = 63/190 (33%), Gaps = 33/190 (17%)
Query: 967 TAGGEVEEGAPPPPTLPPA--------LPPPESPPKVQPEPEPEPGLLLEVEEPGTEE-- 1016
TA + + G PP LPP PP P + P P PG EP
Sbjct: 114 TANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRF---PVPSPGHRSGPPEPQRNRMP 170
Query: 1017 --ERGADTAPTLAPEALPS-----QGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEET 1069
+ P P +PS Q G P G P Q P+ PP T
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP--SPGPTPPPFPGNRGT 228
Query: 1070 EDGSDKVQPPPETPAEEEME----TETEAEALQEKEQ------DDTAAMLADFI-DCPPD 1118
G ++ P + + T + AL +K + ++ + + PP
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 1119 DEKPPPPTEP 1128
+ KPP P+ P
Sbjct: 289 NNKPPVPSTP 298
Score = 32.3 bits (72), Expect = 2.6
Identities = 35/177 (19%), Positives = 51/177 (28%), Gaps = 31/177 (17%)
Query: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA 1030
E + PPP P PP V P P + G+ G P+ P
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP---IQSSPHNRGSPPVPGGPRQPSPGPTP 219
Query: 1031 LPSQG------------EVEREGESPAAG-----PPPQELVEEEPSAPPTLLEEETEDGS 1073
P G + SP + P P ++++P PP +
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279
Query: 1074 DKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
+ V PPP + + + A + PP PPP P S
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPP-----------PPPSRPGPPPLPPSS 325
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 85.9 bits (211), Expect = 2e-16
Identities = 86/310 (27%), Positives = 114/310 (36%), Gaps = 75/310 (24%)
Query: 634 RVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPG--PMPSVGSMPSAGPMP------- 684
R+PP +P + P P P P P P ++ P H G P+P PS GP P
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP-HNRGSPPVPGGPRQPSPGPTPPPFPGNR 226
Query: 685 ---------SAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAG-- 733
P+ S+ P + P PPT + L P PP + P HR
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP---PPPPPVGNRPSIHREAVP 283
Query: 734 -----SNEDPI------LAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLES 782
+N+ P+ A S PPP PP +P + + + +SL S
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSS 343
Query: 783 DSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPP 842
+ PPLP P SG PP PP+ PP P ++ P GPLPPP
Sbjct: 344 ST-----------PPLPSPGRSGPLPP------PPSERPPPPVRDP----PGRSGPLPPP 382
Query: 843 PP-----------PPPP-------VPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININ 884
PP P P V P + P P L P+ P G PP ++ N
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPD-RPSAGAPPPPPPSTSIRNGF 441
Query: 885 SSDEEEEEEE 894
E+E E
Sbjct: 442 QDSPCEDEWE 451
Score = 84.7 bits (208), Expect = 4e-16
Identities = 80/274 (29%), Positives = 98/274 (35%), Gaps = 66/274 (24%)
Query: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAP-PFH-----------PPGPMPSVGSMPSAGPM 683
PPL P G + P PP P F P P H P P P VGS P + P
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 684 P---------------SAGPMPSAGPVPSARPGPPTTANHLGLSV-PGLVSVPPRLLPGP 727
P + P+P PS P PP + G ++ G + P P
Sbjct: 186 PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245
Query: 728 ENHRAGSNEDPILAPSGTPPPTIPPDETFGGR-------VPRPAFVHYDKEEASDVEISL 780
++R P A PPP PP G R VP P + S S
Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSA 302
Query: 781 ESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGP--------PTASPPVPAKEEPEEL 832
S + P PPPPPS PPP+ P+ P + + + P
Sbjct: 303 SSQA------------PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Query: 833 PAAPGPLPPPPP--PPPPV------PGPVTLPPP 858
P GPLPPPP PPPPV GP+ PPP
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPP 384
Score = 56.2 bits (134), Expect = 2e-07
Identities = 63/232 (27%), Positives = 79/232 (34%), Gaps = 35/232 (15%)
Query: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFH------PPGPMPSVGSMPSAGPMPSA 686
P VP + P P PPP P P PP P P ++ S P+PS
Sbjct: 292 PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
Query: 687 GPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPP--------RLLPGPENHRAGSNEDP 738
G P PS RP PP + G S P L PP R LP + S D
Sbjct: 352 GRSGPLPPPPSERP-PPPVRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVD- 408
Query: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798
+P P P +PPD G P P + D E + + P + L
Sbjct: 409 --SPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD--SPCEDEWESRFYFHP--ISDL 462
Query: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVP 850
PPP P T + P+K E + PP PP+P
Sbjct: 463 PPPEPYVQT------------TKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 38.5 bits (88), Expect = 0.036
Identities = 32/102 (31%), Positives = 37/102 (36%), Gaps = 27/102 (26%)
Query: 796 PPLPPP-----------PPSGA----TPPPIAPTGPPTASP---PVPAKEEPEELPAAPG 837
PPL PP PPSG P P +GPP P P + + + P
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 838 PLPPPPPP---------PPPVPGPVTLPPPQLVPEGTPGGGG 870
P+P P P PPVPG P P P PG G
Sbjct: 186 PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG 227
Score = 36.2 bits (82), Expect = 0.18
Identities = 43/166 (25%), Positives = 56/166 (33%), Gaps = 37/166 (22%)
Query: 977 PPPPTLPPALP-----------PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT 1025
PPP P +P PP PP +P P P P +E +R + +
Sbjct: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344
Query: 1026 LAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAE 1085
P LPS G R G P PPP E PP + + G + PPP P
Sbjct: 345 TPP--LPSPG---RSGPLP---PPPSE------RPPPPVRDPPGRSG--PLPPPP--PVS 386
Query: 1086 EEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPP-PPTEPDS 1130
T A + +D P +PP PP P +
Sbjct: 387 RNGSTSRALPATPQLPS-------RSGVDSPRSGPRPPLPPDRPSA 425
Score = 35.8 bits (81), Expect = 0.24
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 10/64 (15%)
Query: 805 GATPPPIAPTGPPTASPPVPAKEEPEELPA-APGPLPPPPPP-----PPPVPG----PVT 854
G+ PP + P G T++ P P P +PG PP P PPP P P +
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS 182
Query: 855 LPPP 858
+PPP
Sbjct: 183 IPPP 186
Score = 35.4 bits (80), Expect = 0.31
Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 25/117 (21%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PPPP+ P P + P + P P P P G+ + A LPS+
Sbjct: 358 PPPPSERPPPPVRDPPGRSGPLPPPPP-----------VSRNGSTSRALPATPQLPSRSG 406
Query: 1037 VEREGESPAAGPPPQELVEEEPSA---PPTLLEEETEDGSDKVQPPPETPAEEEMET 1090
V +SP +GP P L + PSA PP +G ++P E+E E+
Sbjct: 407 V----DSPRSGPRP-PLPPDRPSAGAPPPPPPSTSIRNGFQ------DSPCEDEWES 452
Score = 33.9 bits (76), Expect = 0.90
Identities = 44/190 (23%), Positives = 63/190 (33%), Gaps = 33/190 (17%)
Query: 967 TAGGEVEEGAPPPPTLPPA--------LPPPESPPKVQPEPEPEPGLLLEVEEPGTEE-- 1016
TA + + G PP LPP PP P + P P PG EP
Sbjct: 114 TANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRF---PVPSPGHRSGPPEPQRNRMP 170
Query: 1017 --ERGADTAPTLAPEALPS-----QGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEET 1069
+ P P +PS Q G P G P Q P+ PP T
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP--SPGPTPPPFPGNRGT 228
Query: 1070 EDGSDKVQPPPETPAEEEME----TETEAEALQEKEQ------DDTAAMLADFI-DCPPD 1118
G ++ P + + T + AL +K + ++ + + PP
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 1119 DEKPPPPTEP 1128
+ KPP P+ P
Sbjct: 289 NNKPPVPSTP 298
Score = 32.3 bits (72), Expect = 2.6
Identities = 35/177 (19%), Positives = 51/177 (28%), Gaps = 31/177 (17%)
Query: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA 1030
E + PPP P PP V P P + G+ G P+ P
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP---IQSSPHNRGSPPVPGGPRQPSPGPTP 219
Query: 1031 LPSQG------------EVEREGESPAAG-----PPPQELVEEEPSAPPTLLEEETEDGS 1073
P G + SP + P P ++++P PP +
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279
Query: 1074 DKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
+ V PPP + + + A + PP PPP P S
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPP-----------PPPSRPGPPPLPPSS 325
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 85.9 bits (211), Expect = 2e-16
Identities = 83/266 (31%), Positives = 93/266 (34%), Gaps = 82/266 (30%)
Query: 633 PRVPPLQ----PMGPTCPTPAPVPPPEAP---SPFRAPPFHPPGPMPSVGSMPSAGPMPS 685
P+ PP Q P GP P PPP+ SP R+PP P GP P G+ P P P
Sbjct: 57 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP-RSPPGKPQGPPPQGGNQPQGPPPPP 115
Query: 686 A---GPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP 742
GP P G P GPP PG PP P+ ++ S P P
Sbjct: 116 GKPQGPPPQGGNRPQ---GPPP---------PGKPQGPP-----PQGDKSRSPRSPPGKP 158
Query: 743 SGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLP--- 799
G PP GG P+G PP P
Sbjct: 159 QGPPPQ--------GGN-------------------------------QPQGPPPPPGKP 179
Query: 800 --PPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPP-----PPPPPPVPGP 852
PPP G P P G P PP K + P PPP P PPP PG
Sbjct: 180 QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK 239
Query: 853 VTLPPPQ--LVPEGTPGGG---GPPA 873
PPPQ P+G P G GPPA
Sbjct: 240 PQGPPPQGGNKPQGPPPPGKPQGPPA 265
Score = 77.0 bits (188), Expect = 9e-14
Identities = 75/245 (30%), Positives = 91/245 (37%), Gaps = 52/245 (21%)
Query: 633 PRVPPLQ----PMGPTCPTPAPVPPPEAP---SPFRAPPFHPPGPMPSVGSMPSAGPMPS 685
P+ PP Q P GP P PPP+ SP R+PP P GP P G+ P P P
Sbjct: 118 PQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP-RSPPGKPQGPPPQGGNQPQGPPPPP 176
Query: 686 A---GPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP 742
GP P G P GPP PG PP P+ ++ S++ P P
Sbjct: 177 GKPQGPPPQGGKKPQ---GPPP---------PGKPQGPP-----PQGDKSRSSQSPPGKP 219
Query: 743 SGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPP-- 800
G PP GG P+ K + + + P G P PP
Sbjct: 220 QGPPPQ--------GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-----PPGKPQGPPAQ 266
Query: 801 --PPPSGATPPPIAPTGPP------TASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852
A PP P GPP PP PA P++ P AP P PP PP G
Sbjct: 267 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ-PQAPPAGQPQGPPRPPQGGR 325
Query: 853 VTLPP 857
+ PP
Sbjct: 326 PSRPP 330
Score = 60.1 bits (144), Expect = 1e-08
Identities = 66/234 (28%), Positives = 75/234 (32%), Gaps = 92/234 (39%)
Query: 672 PSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHR 731
PS+ + GP P G P P P +P P PP+
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP----------------PPQ--------- 63
Query: 732 AGSNEDPILAPSGTPPPTIP---PDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSV 788
G N+ P G PPP P P + R PR
Sbjct: 64 -GGNK-----PQGPPPPGKPQGPPPQGDKSRSPRS------------------------- 92
Query: 789 VIVPEGLPPLPPPP----PSGATPPPIAPTGPP------TASPPVPAKE-------EPEE 831
P G P PPP P G PPP P GPP PP P K +
Sbjct: 93 ---PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSR 149
Query: 832 LPAAPGPLPPPPPP--------PPPVPGPVTLPPPQ--LVPEGTPGGG---GPP 872
P +P P PPP PPP PG PPPQ P+G P G GPP
Sbjct: 150 SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
Score = 53.1 bits (126), Expect = 1e-06
Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 19/115 (16%)
Query: 969 GGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028
GG +G PPPP P PPP+ K P+ P PG + G + G+ + +P
Sbjct: 226 GGNQPQGPPPPPGKPQG-PPPQGGNK--PQGPPPPG-----KPQGPPAQGGSKSQSARSP 277
Query: 1029 EALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083
P QG ++EG +P PPP ++P APP + + Q PP P
Sbjct: 278 PGKP-QGPPQQEGNNPQGPPPPAGGNPQQPQAPP----------AGQPQGPPRPP 321
Score = 52.8 bits (125), Expect = 2e-06
Identities = 44/161 (27%), Positives = 59/161 (36%), Gaps = 23/161 (14%)
Query: 949 EDEEEEEELEEVEDLEFGTA--GGEVEEGAPPPPTLP----------PALPPPESPPKVQ 996
ED +EE + G + GG +G PPPP P P PPP P+
Sbjct: 21 EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 80
Query: 997 P-------EPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAA--- 1046
P P PG G + +G P P+ P QG +G P
Sbjct: 81 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPPPQGGNRPQGPPPPGKPQ 139
Query: 1047 GPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEE 1087
GPPPQ P +PP + G ++ Q PP P + +
Sbjct: 140 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
Score = 51.6 bits (122), Expect = 4e-06
Identities = 39/118 (33%), Positives = 46/118 (38%), Gaps = 26/118 (22%)
Query: 781 ESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPP------TASPPVPAKE------- 827
+ +S + P+G P P G PPP P GPP PP P K
Sbjct: 25 QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84
Query: 828 EPEELPAAPGPLPPPPPP--------PPPVPGPVTLPPPQ--LVPEGTPGGG---GPP 872
+ P +P P PPP PPP PG PPPQ P+G P G GPP
Sbjct: 85 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142
Score = 49.3 bits (116), Expect = 2e-05
Identities = 40/129 (31%), Positives = 57/129 (44%), Gaps = 15/129 (11%)
Query: 969 GGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028
GG +G PPPP P PPP+ K P+ P PG + P ++ R + + P P
Sbjct: 165 GGNQPQGPPPPPGKPQG-PPPQGGKK--PQGPPPPG-KPQGPPPQGDKSRSSQSPPG-KP 219
Query: 1029 EALPSQGEVEREGESP----AAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQ----PP- 1079
+ P QG + +G P GPPPQ + + PP + G K Q PP
Sbjct: 220 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279
Query: 1080 -PETPAEEE 1087
P+ P ++E
Sbjct: 280 KPQGPPQQE 288
Score = 48.5 bits (114), Expect = 4e-05
Identities = 40/132 (30%), Positives = 52/132 (39%), Gaps = 21/132 (15%)
Query: 969 GGEVEEGAPPPPTLPPALPP-------PESPPKVQPEPEPEPGLLLEVEEPGTEEERG-- 1019
GG +G PPPP P PP P SPP P P+ G + P + +G
Sbjct: 125 GGNRPQG-PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183
Query: 1020 -------ADTAPTLAPEALPSQGEVEREGESPAA---GPPPQELVEEE-PSAPPTLLEEE 1068
P P+ P QG+ R +SP GPPPQ + + P PP +
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 243
Query: 1069 TEDGSDKVQPPP 1080
G +K Q PP
Sbjct: 244 PPQGGNKPQGPP 255
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 85.5 bits (210), Expect = 3e-16
Identities = 73/216 (33%), Positives = 100/216 (46%), Gaps = 9/216 (4%)
Query: 879 TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEE-EEEEFEEEFEE 937
T + + E+EEEE +EEEEEE+E + D EE E+E E+EE E+EE E E E
Sbjct: 516 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 575
Query: 938 EEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQP 997
E E E +EE++ EE+ EE+ E+L A E E A P P +SP V
Sbjct: 576 EGEEAEAKEEKKVEEKSEEVATKEEL-VADAKVEKPEKAKSPVPKSPVEEKGKSP--VPK 632
Query: 998 EPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEE 1057
P E G + P EE+G P E + E A P P+ VEE
Sbjct: 633 SPVEEKGKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA 690
Query: 1058 PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETE 1093
S E+ E+ +V+ E P EE++E + E
Sbjct: 691 KSKAEVGKGEQKEEEEKEVK---EAPKEEKVEKKEE 723
Score = 76.6 bits (187), Expect = 1e-13
Identities = 77/254 (30%), Positives = 112/254 (44%), Gaps = 40/254 (15%)
Query: 872 PALEEDLTVININSSDEEEEEEEEEEEEEEEEE-----EEEEDFEEEEEDEEEYFEEEEE 926
P +E + +E EE + E+E+ E EE EE +EE +E E+EEE
Sbjct: 439 PKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 498
Query: 927 EEEEFEE-------------EFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG----TAG 969
E E EE E +EEEGE EEEE +E+EEEE+E + + E G
Sbjct: 499 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 558
Query: 970 GEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADT---APTL 1026
E EEG E+ K + + E + EE T+EE AD P
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS------EEVATKEELVADAKVEKPEK 612
Query: 1027 APEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEE 1086
A +P + VE +G+SP P+ VEE+ +P E + S P P++P EE
Sbjct: 613 AKSPVP-KSPVEEKGKSPV----PKSPVEEKGKSPVPKSPVEEKGKS----PVPKSPVEE 663
Query: 1087 EMETETEAEALQEK 1100
+ ++ ++EK
Sbjct: 664 KGKSPVSKSPVEEK 677
Score = 73.2 bits (178), Expect = 1e-12
Identities = 74/275 (26%), Positives = 116/275 (42%), Gaps = 29/275 (10%)
Query: 859 QLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEE--EEEEDFEEEEED 916
++ + +P P ++E+ EEEEEE+E + ++ EE E+E E+EE
Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 564
Query: 917 EEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE----EELEEVEDLEFGTAGGEV 972
E+E E E E E E EE +EE ++EE+ EE +EE ++E+ E + V
Sbjct: 565 EQE--EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 622
Query: 973 EEGAPPPPTLPPALPPPESPPKVQP--EPEPEPGLLLEVEEPGTE-------EERGADTA 1023
EE P P +SP P E P VEE G EE+
Sbjct: 623 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 682
Query: 1024 PTLAPEALPS-----QGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQP 1078
P E S +GE + E E P +E VE++ P + E++ + K +
Sbjct: 683 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 742
Query: 1079 PPE-------TPAEEEMETETEAEALQEKEQDDTA 1106
E E ET+ E + LQ++++ + A
Sbjct: 743 VAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKA 777
Score = 59.3 bits (142), Expect = 2e-08
Identities = 56/224 (25%), Positives = 95/224 (42%), Gaps = 19/224 (8%)
Query: 881 ININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940
I I+S ++ + E + + + + EE + + E+++ E E EE +EE+
Sbjct: 430 ITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKK 489
Query: 941 ELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPE 1000
E EE+EEE E EEEE+ + TA EE E + + E E
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG----------EKEEEEGQEEEEEE 539
Query: 1001 PEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSA 1060
E + EE G+E+E ++ E +GE E E E A ++ VEE+
Sbjct: 540 DEGAKSDQAEEGGSEKEGSSE-----KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 594
Query: 1061 PPT----LLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEK 1100
T + + + E P P++P EE+ ++ ++EK
Sbjct: 595 VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 638
Score = 50.4 bits (119), Expect = 9e-06
Identities = 62/232 (26%), Positives = 97/232 (41%), Gaps = 35/232 (15%)
Query: 816 PPTASPPVPAKEEPEELPAAPGPLPP------PPPPPPPVP--GPVTLPPPQLVPEGTPG 867
P A PVP K EE +P P P P P PV G +P + +G
Sbjct: 610 PEKAKSPVP-KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 668
Query: 868 GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE 927
P E+ + + + +E + + E + E++EEEE+ E +E +EE E++EE+
Sbjct: 669 VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKEAPKEEKVEKKEEK 724
Query: 928 EEEFEEEFEEEEGELEEE---------------EEEEDEEEEEELEEVEDLEFGTAGGEV 972
++ E+ + E EE E+E EE + +E E + G GG
Sbjct: 725 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE 784
Query: 973 EEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT--EEERGADT 1022
EEG+ A + V E E + + E +E G+ EEE+G T
Sbjct: 785 EEGSD-----KGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Score = 48.1 bits (113), Expect = 5e-05
Identities = 58/228 (25%), Positives = 90/228 (39%), Gaps = 31/228 (13%)
Query: 825 AKEEPEELPAAPGPLPP------PPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDL 878
AK E E +P P P P P PV P P+ E P + E+
Sbjct: 605 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 664
Query: 879 TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
++ S EE+ + + EE + + + + E+ EEE E +E +EE E+ EE+
Sbjct: 665 GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 724
Query: 939 EGELEEEEEEEDEEEEEELEEV----EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPK 994
++ E+++ E +EE + EV + ++ EEG P
Sbjct: 725 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP----------------- 767
Query: 995 VQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE 1042
+Q E E E E G+EEE A E + GEVE + E
Sbjct: 768 LQQEKEKEKA----GGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEE 811
Score = 47.8 bits (112), Expect = 6e-05
Identities = 67/241 (27%), Positives = 97/241 (40%), Gaps = 63/241 (26%)
Query: 895 EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE 954
++ + E + + + F EE +E + +E+ E EE EE ++EE++E EE+E
Sbjct: 437 QKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 496
Query: 955 EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014
EE E E+ E A P A PE + E G + EE G
Sbjct: 497 EEPEAEEE----------EVAAKKSPVKATA-----------PEVKEEEGE--KEEEEGQ 533
Query: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074
EEE D A +G E+EG S E+E E E E+G
Sbjct: 534 EEEEEEDEG---AKSDQAEEGGSEKEGSS-----------EKE--------EGEQEEG-- 569
Query: 1075 KVQPPPETPAEEEMETETEAEALQEKEQDDTA-------AMLADFIDCPPDDEKPPPPTE 1127
ET AE E E EAEA +EK+ ++ + ++AD P+ K P P
Sbjct: 570 ------ETEAEAEGE---EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620
Query: 1128 P 1128
P
Sbjct: 621 P 621
Score = 35.4 bits (80), Expect = 0.31
Identities = 56/250 (22%), Positives = 92/250 (36%), Gaps = 42/250 (16%)
Query: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE-EEFEEEFEEEEGE 941
I S+ EE E + + + E E +E E + EE + +++ ++ E E
Sbjct: 310 IRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENE 369
Query: 942 LEEEEEEEDEEEEE-------------------ELEEVEDLEFGTAGGEVEEGA---PPP 979
L + E E +L E E+ F T G + PP
Sbjct: 370 LRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPP 429
Query: 980 PTLPPALPPPE-SPPKVQPEPEPEPGLLLEVEEPGTEEERGA--DTAPTLAPEALPSQGE 1036
T+ + P+ PK++ + + + +EE E+E+ + + E S E
Sbjct: 430 ITISSKIQKPKVEAPKLKVQHKFVEEI---IEETKVEDEKSEMEEALTAITEELAVSMKE 486
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEA 1096
++E E EEEP A EEE V+ EEE E E E
Sbjct: 487 EKKEAA---------EEKEEEPEAE----EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ 533
Query: 1097 LQEKEQDDTA 1106
+E+E+D+ A
Sbjct: 534 EEEEEEDEGA 543
Score = 30.8 bits (68), Expect = 7.6
Identities = 56/272 (20%), Positives = 94/272 (34%), Gaps = 44/272 (16%)
Query: 727 PENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDD 786
PE ++ + P+ +P P P +E VP+ K + + S
Sbjct: 610 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 669
Query: 787 SVVIVPE-GLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEP-EELPAAPGPLPPPPP 844
S V E P+P P A G KE P EE P P
Sbjct: 670 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVP 729
Query: 845 PPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTV---ININSSDEEEEEEEEEEEEEE 901
PV A+ E +T+ + ++ E +EE + ++E+E
Sbjct: 730 EKKKAESPVK----------------EEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 773
Query: 902 EEEEEEEDFEEEE--------------------EDEEEYFEEEEEEEEEFEEEFEEEEGE 941
+E+ E EEE E +EE +E +E+ EEE
Sbjct: 774 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 833
Query: 942 LE---EEEEEEDEEEEEELEEVEDLEFGTAGG 970
L+ +E++ ++ EE++ + +E T+ G
Sbjct: 834 LDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 865
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 85.5 bits (210), Expect = 3e-16
Identities = 73/216 (33%), Positives = 100/216 (46%), Gaps = 9/216 (4%)
Query: 879 TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEE-EEEEFEEEFEE 937
T + + E+EEEE +EEEEEE+E + D EE E+E E+EE E+EE E E E
Sbjct: 140 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 199
Query: 938 EEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQP 997
E E E +EE++ EE+ EE+ E+L A E E A P P +SP V
Sbjct: 200 EGEEAEAKEEKKVEEKSEEVATKEEL-VADAKVEKPEKAKSPVPKSPVEEKGKSP--VPK 256
Query: 998 EPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEE 1057
P E G + P EE+G P E + E A P P+ VEE
Sbjct: 257 SPVEEKGKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA 314
Query: 1058 PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETE 1093
S E+ E+ +V+ E P EE++E + E
Sbjct: 315 KSKAEVGKGEQKEEEEKEVK---EAPKEEKVEKKEE 347
Score = 76.6 bits (187), Expect = 1e-13
Identities = 77/254 (30%), Positives = 112/254 (44%), Gaps = 40/254 (15%)
Query: 872 PALEEDLTVININSSDEEEEEEEEEEEEEEEEE-----EEEEDFEEEEEDEEEYFEEEEE 926
P +E + +E EE + E+E+ E EE EE +EE +E E+EEE
Sbjct: 63 PKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 122
Query: 927 EEEEFEE-------------EFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG----TAG 969
E E EE E +EEEGE EEEE +E+EEEE+E + + E G
Sbjct: 123 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 182
Query: 970 GEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADT---APTL 1026
E EEG E+ K + + E + EE T+EE AD P
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS------EEVATKEELVADAKVEKPEK 236
Query: 1027 APEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEE 1086
A +P + VE +G+SP P+ VEE+ +P E + S P P++P EE
Sbjct: 237 AKSPVP-KSPVEEKGKSPV----PKSPVEEKGKSPVPKSPVEEKGKS----PVPKSPVEE 287
Query: 1087 EMETETEAEALQEK 1100
+ ++ ++EK
Sbjct: 288 KGKSPVSKSPVEEK 301
Score = 73.2 bits (178), Expect = 1e-12
Identities = 74/275 (26%), Positives = 116/275 (42%), Gaps = 29/275 (10%)
Query: 859 QLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEE--EEEEDFEEEEED 916
++ + +P P ++E+ EEEEEE+E + ++ EE E+E E+EE
Sbjct: 129 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 188
Query: 917 EEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE----EELEEVEDLEFGTAGGEV 972
E+E E E E E E EE +EE ++EE+ EE +EE ++E+ E + V
Sbjct: 189 EQE--EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 246
Query: 973 EEGAPPPPTLPPALPPPESPPKVQP--EPEPEPGLLLEVEEPGTE-------EERGADTA 1023
EE P P +SP P E P VEE G EE+
Sbjct: 247 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 306
Query: 1024 PTLAPEALPS-----QGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQP 1078
P E S +GE + E E P +E VE++ P + E++ + K +
Sbjct: 307 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 366
Query: 1079 PPE-------TPAEEEMETETEAEALQEKEQDDTA 1106
E E ET+ E + LQ++++ + A
Sbjct: 367 VAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKA 401
Score = 59.3 bits (142), Expect = 2e-08
Identities = 56/224 (25%), Positives = 95/224 (42%), Gaps = 19/224 (8%)
Query: 881 ININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940
I I+S ++ + E + + + + EE + + E+++ E E EE +EE+
Sbjct: 54 ITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKK 113
Query: 941 ELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPE 1000
E EE+EEE E EEEE+ + TA EE E + + E E
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG----------EKEEEEGQEEEEEE 163
Query: 1001 PEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSA 1060
E + EE G+E+E ++ E +GE E E E A ++ VEE+
Sbjct: 164 DEGAKSDQAEEGGSEKEGSSE-----KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 218
Query: 1061 PPT----LLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEK 1100
T + + + E P P++P EE+ ++ ++EK
Sbjct: 219 VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 262
Score = 50.4 bits (119), Expect = 9e-06
Identities = 62/232 (26%), Positives = 97/232 (41%), Gaps = 35/232 (15%)
Query: 816 PPTASPPVPAKEEPEELPAAPGPLPP------PPPPPPPVP--GPVTLPPPQLVPEGTPG 867
P A PVP K EE +P P P P P PV G +P + +G
Sbjct: 234 PEKAKSPVP-KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 292
Query: 868 GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE 927
P E+ + + + +E + + E + E++EEEE+ E +E +EE E++EE+
Sbjct: 293 VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKEAPKEEKVEKKEEK 348
Query: 928 EEEFEEEFEEEEGELEEE---------------EEEEDEEEEEELEEVEDLEFGTAGGEV 972
++ E+ + E EE E+E EE + +E E + G GG
Sbjct: 349 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE 408
Query: 973 EEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT--EEERGADT 1022
EEG+ A + V E E + + E +E G+ EEE+G T
Sbjct: 409 EEGSD-----KGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 455
Score = 48.1 bits (113), Expect = 5e-05
Identities = 58/228 (25%), Positives = 90/228 (39%), Gaps = 31/228 (13%)
Query: 825 AKEEPEELPAAPGPLPP------PPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDL 878
AK E E +P P P P P PV P P+ E P + E+
Sbjct: 229 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 288
Query: 879 TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
++ S EE+ + + EE + + + + E+ EEE E +E +EE E+ EE+
Sbjct: 289 GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 348
Query: 939 EGELEEEEEEEDEEEEEELEEV----EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPK 994
++ E+++ E +EE + EV + ++ EEG P
Sbjct: 349 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP----------------- 391
Query: 995 VQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE 1042
+Q E E E E G+EEE A E + GEVE + E
Sbjct: 392 LQQEKEKEKA----GGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEE 435
Score = 47.8 bits (112), Expect = 6e-05
Identities = 67/241 (27%), Positives = 97/241 (40%), Gaps = 63/241 (26%)
Query: 895 EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE 954
++ + E + + + F EE +E + +E+ E EE EE ++EE++E EE+E
Sbjct: 61 QKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 120
Query: 955 EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014
EE E E+ E A P A PE + E G + EE G
Sbjct: 121 EEPEAEEE----------EVAAKKSPVKATA-----------PEVKEEEGE--KEEEEGQ 157
Query: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074
EEE D A +G E+EG S E+E E E E+G
Sbjct: 158 EEEEEEDEG---AKSDQAEEGGSEKEGSS-----------EKE--------EGEQEEG-- 193
Query: 1075 KVQPPPETPAEEEMETETEAEALQEKEQDDTA-------AMLADFIDCPPDDEKPPPPTE 1127
ET AE E E EAEA +EK+ ++ + ++AD P+ K P P
Sbjct: 194 ------ETEAEAEGE---EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244
Query: 1128 P 1128
P
Sbjct: 245 P 245
Score = 32.0 bits (71), Expect = 3.4
Identities = 40/157 (25%), Positives = 63/157 (40%), Gaps = 22/157 (14%)
Query: 956 ELEEVEDLEFGTAGGEVEEGA---PPPPTLPPALPPPE-SPPKVQPEPEPEPGLLLEVEE 1011
+L E E+ F T G + PP T+ + P+ PK++ + + + +EE
Sbjct: 27 KLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEI---IEE 83
Query: 1012 PGTEEERGA--DTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEET 1069
E+E+ + + E S E ++E E EEEP A EEE
Sbjct: 84 TKVEDEKSEMEEALTAITEELAVSMKEEKKEAA---------EEKEEEPEAE----EEEV 130
Query: 1070 EDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTA 1106
V+ EEE E E E +E+E+D+ A
Sbjct: 131 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 167
Score = 30.8 bits (68), Expect = 7.6
Identities = 56/272 (20%), Positives = 94/272 (34%), Gaps = 44/272 (16%)
Query: 727 PENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDD 786
PE ++ + P+ +P P P +E VP+ K + + S
Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293
Query: 787 SVVIVPE-GLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEP-EELPAAPGPLPPPPP 844
S V E P+P P A G KE P EE P P
Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVP 353
Query: 845 PPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTV---ININSSDEEEEEEEEEEEEEE 901
PV A+ E +T+ + ++ E +EE + ++E+E
Sbjct: 354 EKKKAESPVK----------------EEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 397
Query: 902 EEEEEEEDFEEEE--------------------EDEEEYFEEEEEEEEEFEEEFEEEEGE 941
+E+ E EEE E +EE +E +E+ EEE
Sbjct: 398 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 457
Query: 942 LE---EEEEEEDEEEEEELEEVEDLEFGTAGG 970
L+ +E++ ++ EE++ + +E T+ G
Sbjct: 458 LDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 489
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 85.5 bits (210), Expect = 3e-16
Identities = 94/322 (29%), Positives = 126/322 (39%), Gaps = 54/322 (16%)
Query: 621 SEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMP-SVGSMPS 679
+E ++ A ++PP P+ P P+P P PP + SP PP PP P P S +PS
Sbjct: 387 AEEMMPAAEKEEAKLPP-PPLTPPAPSPPPPLPPPSTSP--PPPLCPPPPPPVSPPPLPS 443
Query: 680 AGPMPSAGPMPSAGP--VPSA----RPGPPTTAN-----HLGLSVPGLVSVPPRLLPGPE 728
P P+ + P VP+ R PP T + + P S P P P
Sbjct: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPP---TPTPS 500
Query: 729 NHRAGSNED-PILAPSGTP---------PPTIPPDETFGGRVPRPAFVHYDKEEASDVEI 778
G ED P +AP T P + + + PR F+ D + VE+
Sbjct: 501 TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR-RFMDEDPPKPPKVEV 559
Query: 779 SLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAK-----EEP---- 829
S V+ P P P P+ PP APT PP+ P+P K EP
Sbjct: 560 S-------PVLRPPITTSPPVPQEPAPVPSPPRAPT-PPSTPVPLPEKRRSILREPTFRW 611
Query: 830 ----EELPAAPGPLPPPPPPPPPVPGPVTLPPPQLV---PEGTPGGGGPPALEEDLTVIN 882
ELP P P PPPPP P P P P T L+ P+ TP E LT
Sbjct: 612 TSLTRELPPPP-PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP 670
Query: 883 INSSDEEEEEEEEEEEEEEEEE 904
+ + + E E ++ E E
Sbjct: 671 LGAPEAPEPEPPPADDSPAEPE 692
Score = 74.3 bits (181), Expect = 6e-13
Identities = 99/373 (26%), Positives = 141/373 (37%), Gaps = 67/373 (17%)
Query: 799 PPPPPSGATPP--PIAPTGPPTASPPVPAKEEPEELPAAPG----PLPPPPPPPPPV--- 849
P P S A P P G P P P + + + + A P P PPPP PV
Sbjct: 203 PQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQ 262
Query: 850 -----------PGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEE---- 894
PGP T G GG G VI S ++ + +
Sbjct: 263 TGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLG 322
Query: 895 -EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEE 953
E + + + EE +D + + +++E+ ++ EEE+ +EEEE+D+E
Sbjct: 323 LESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEK----KEEEEKDKEG 378
Query: 954 EEELEEVEDLEFGTAGGEVEEGAPPPPTLPPA------LPPPES--PPKVQPEPEP--EP 1003
EE+ E E A + E PPPP PPA LPPP + PP + P P P P
Sbjct: 379 EEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP 438
Query: 1004 GLLLEVEEPGTEEERGADTAPTL---------APEALPSQGEVEREGESPAAGPPPQELV 1054
L P +EE+ P + P PSQ E E+ AGP
Sbjct: 439 PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQ---RAEREAARAGP------ 489
Query: 1055 EEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFID 1114
E ++PPT G PP ++P T T + +++ +A + I
Sbjct: 490 --EGTSPPTPTPSTATGG-----PPEDSPTVAPKST-TFLKNIRQFIMPVVSARSSRVIK 541
Query: 1115 CPPD--DEKPPPP 1125
P DE PP P
Sbjct: 542 TPRRFMDEDPPKP 554
Score = 57.4 bits (137), Expect = 8e-08
Identities = 78/344 (22%), Positives = 103/344 (29%), Gaps = 42/344 (12%)
Query: 769 DKEEASDVEISLESDSDDSVVIVPEGL------PPLPPPPPSGATPPPIAPTGPPTASPP 822
+KEE + E + + + + P L PP P PPPS + PPP+ P PP SPP
Sbjct: 380 EKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPP 439
Query: 823 VPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVIN 882
P P PPPPP PP +VP G P L
Sbjct: 440 -----------------PLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAER 482
Query: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
+ E ED + + + +
Sbjct: 483 EAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKT 542
Query: 943 EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPE 1002
+ED + ++E L P P PP P P S P P PE
Sbjct: 543 PRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP--VPLPEKR 600
Query: 1003 PGLLLEVEEPGTEEERGADTAPTL-----APEALPSQGEVEREG---ESPAAGPPPQEL- 1053
+L E T R P AP P+ R +P P L
Sbjct: 601 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK 660
Query: 1054 VEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL 1097
+ E PP L E P PE P ++ E E A+
Sbjct: 661 IYESVLTPPPLGAPEA--------PEPEPPPADDSPAEPEPRAV 696
Score = 57.4 bits (137), Expect = 8e-08
Identities = 65/241 (26%), Positives = 80/241 (33%), Gaps = 54/241 (22%)
Query: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709
P PP SP PP P+P P+ P P P P + PVP P + L
Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQE---PAPVPSPPRAPTPPSTPVPL----PEKRRSIL 604
Query: 710 GLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYD 769
S+ L P P AP P P+ PP R RP +
Sbjct: 605 REPTFRWTSLTRELPPPPP------------APPPPPAPSPPPAPATSSR--RPLLLRAP 650
Query: 770 KEEASDVEISL-ESDSDDSVVIVPEGLPPLPPPPP-SGATPPPIA---------PTGPPT 818
+ S+ + + ES + PE P PPP S A P P A P P
Sbjct: 651 QFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPV 710
Query: 819 ASPPVPAKEEPEELPAA----------------------PGPLPPPPPPPPPVPGPVTLP 856
+ PV A+ P PA P LPPP P P P P +P
Sbjct: 711 VTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMP 770
Query: 857 P 857
P
Sbjct: 771 P 771
Score = 57.0 bits (136), Expect = 1e-07
Identities = 57/202 (28%), Positives = 73/202 (36%), Gaps = 35/202 (17%)
Query: 665 FHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLL 724
+ P GP + +A + P+ P PP + L VPG
Sbjct: 1783 YRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVL---VPG--------- 1830
Query: 725 PGPENHRAGSNEDPILAP-SGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD 783
PE H N DP L P SG+ PP P + G R+ P + + L S
Sbjct: 1831 -APERHSPIQNLDPPLRPDSGSAPPPAPRSFS-GARIKVPNYSPSRRPLGGVSFGPLPSP 1888
Query: 784 SDDSVV---IVPEGLPPLPPPPPSGATPPPIAPTGPPT--ASPPVPAKEEPEELP----- 833
S + I G P P PP P P+AP PP+ ASPP+ + P
Sbjct: 1889 GSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVV 1948
Query: 834 ----------AAPGPLPPPPPP 845
A PGP P PPPP
Sbjct: 1949 TALTPTSGELAPPGPAPSPPPP 1970
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/86 (38%), Positives = 39/86 (45%), Gaps = 13/86 (15%)
Query: 797 PLPPPPPSGATPPPIAPTGPPT-ASPPVPAKEEPEELPAAPGPLPPPPPPPPPV-----P 850
P+PPP PP I+PT P + PP P LP P PPPPPPP+
Sbjct: 2210 PVPPPVKQPPLPPTISPTAPTSWTLPPGPLL---GVLPVVGVVRPAPPPPPPPLTLVLSS 2266
Query: 851 GPVTLPPPQLV---PEGTPGGGGPPA 873
GP + PP Q + T G PPA
Sbjct: 2267 GPAS-PPRQAIRVKRVSTFSGRSPPA 2291
Score = 42.0 bits (97), Expect = 0.003
Identities = 42/141 (29%), Positives = 54/141 (38%), Gaps = 30/141 (21%)
Query: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPP---------GPMPSVGS-------MPS 679
PPL+P + P PAP + + + P + P GP+PS GS +P+
Sbjct: 1843 PPLRPDSGSAPPPAP--RSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPT 1900
Query: 680 AG-------PMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRA 732
G P S P P A P +R P L VP SV L P +
Sbjct: 1901 VGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTP-----TS 1955
Query: 733 GSNEDPILAPSGTPPPTIPPD 753
G P APS PP + PD
Sbjct: 1956 GELAPPGPAPSPPPPEDLGPD 1976
Score = 42.0 bits (97), Expect = 0.003
Identities = 79/320 (24%), Positives = 102/320 (31%), Gaps = 80/320 (25%)
Query: 617 SSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPP-EAPSPFRAPPFHPPGP----M 671
S + S L T L P PP + PT + PP APSP PP GP M
Sbjct: 1926 SRWASPPLKTSPQLRVP--PPTSVVTALTPTSGELAPPGPAPSP---PPPEDLGPDFEDM 1980
Query: 672 PSVGSMPSA---------GPMPSAGPMPSAGPVPSARPGPPTTAN----------HLGLS 712
V + +A G P + +AG + S+ GP ++ H ++
Sbjct: 1981 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT 2040
Query: 713 VPGLVSVPPRLLPGPE--------NHRAGSNEDPILAP--SGTPP--PTIPPDETFGGRV 760
V + P PG + S + + P GTPP P + G
Sbjct: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100
Query: 761 PRPAFVHYDKEEASDVEI-SLESDSDDSVVIVPEGLPPLPP-----PPPSGATPPPIAPT 814
R E D + +L D E LPP PP P G T P PT
Sbjct: 2101 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT 2160
Query: 815 GP----------------PTASPPVPAKEE--------------PEELPAAPGPLPPPPP 844
P PP PA + E P P+ PP
Sbjct: 2161 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL 2220
Query: 845 PP---PPVPGPVTLPPPQLV 861
PP P P TLPP L+
Sbjct: 2221 PPTISPTAPTSWTLPPGPLL 2240
Score = 41.6 bits (96), Expect = 0.004
Identities = 71/295 (24%), Positives = 100/295 (33%), Gaps = 61/295 (20%)
Query: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709
PVPPP + PP PP P+ + + P P G +P G V RP PP L
Sbjct: 2210 PVPPP-----VKQPPL-PPTISPTAPTSWTLPPGPLLGVLPVVGVV---RPAPPPPPPPL 2260
Query: 710 GLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYD 769
L + + PPR + SG PP PP + PR
Sbjct: 2261 TLVLSSGPASPPR---------QAIRVKRVSTFSGRSPPAPPPY-----KAPR------- 2299
Query: 770 KEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPI-APTGPPTASPPVPAKEE 828
L+ D + S E P +P G + + PT P +
Sbjct: 2300 ----------LDEDGEAS-----EDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPA 2344
Query: 829 PEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDE 888
EE +PGPL P LP P+ P P G LE + +S
Sbjct: 2345 GEE---SPGPLQERSP---------LLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSS 2392
Query: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE---EEFEEEEG 940
EEE +++E + + E E+ + E E E + E+ +E G
Sbjct: 2393 EEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARG 2447
Score = 40.8 bits (94), Expect = 0.007
Identities = 69/268 (25%), Positives = 93/268 (34%), Gaps = 38/268 (14%)
Query: 554 PLVMGVQQGEVLGSSPYTSSRCRRELYCL--LLALLLAPSPRCPPPLACALQAFS-LGQR 610
PL G Q + L +SP +R L + L L P+P P P + + LGQ
Sbjct: 2141 PLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQ- 2199
Query: 611 EDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGP 670
V A P PP++ P P P AP+ + PP G
Sbjct: 2200 ------------VFVKMAGEGEPVPPPVKQ-----PPLPPTISPTAPTSWTLPPGPLLGV 2242
Query: 671 MPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENH 730
+P VG + A P P P P + S PP A + V + + R P P +
Sbjct: 2243 LPVVGVVRPAPPPP---PPPLTLVLSSGPASPPRQA----IRVKRVSTFSGRSPPAPPPY 2295
Query: 731 RAGSNEDPILAPSGTPPPTIPPDETFG-GRVPRPAFVHYDKEEASDVEISLESDSDDSVV 789
+A P L G P G G R D++ E ++S
Sbjct: 2296 KA-----PRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPG 2350
Query: 790 IVPEGLPPLPPPPPSGATPPPIAPTGPP 817
+ E P LP P PP P GPP
Sbjct: 2351 PLQERSPLLPLPEDG----PPQVPDGPP 2374
Score = 39.3 bits (90), Expect = 0.021
Identities = 41/160 (25%), Positives = 57/160 (35%), Gaps = 23/160 (14%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PPPP PP PPP P P LLL + E L P L +
Sbjct: 619 PPPPPAPP--PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP-- 674
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME------- 1089
E+P PPP + EP P + + P TP + E+
Sbjct: 675 -----EAPEPEPPPADDSPAEPE--PRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPAL 727
Query: 1090 ---TETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPT 1126
+T+A+ LQ + T +L + PP + PPP+
Sbjct: 728 SNGPQTQAQLLQPLQALQT-QLLPQALP-PPQPQLQPPPS 765
Score = 33.5 bits (75), Expect = 1.2
Identities = 42/156 (26%), Positives = 56/156 (35%), Gaps = 30/156 (19%)
Query: 997 PEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ-GEVER-EGESPAAGP-PPQEL 1053
PE E G E E G + D AP+ AL SQ G R G P PP L
Sbjct: 109 PEEESSDGESDEEEFQGFHSDE--DVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRL 166
Query: 1054 VEEEPSAPPTLLEEETEDGSDKV----------QPPPETPAEEEMETET----------- 1092
+ P+ P T + E+G++++ P+ P E T
Sbjct: 167 ADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGR 226
Query: 1093 EAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
A + K+Q A A I P +PPPP P
Sbjct: 227 PAGPCRRKQQAVVVAEAAVTIPKP----EPPPPVVP 258
Score = 33.5 bits (75), Expect = 1.2
Identities = 37/131 (28%), Positives = 47/131 (35%), Gaps = 27/131 (20%)
Query: 974 EGAP-PPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
EG P PPP P LPP SP P PG LL V LP
Sbjct: 2207 EGEPVPPPVKQPPLPPTISPTAPTSWTLP-PGPLLGV---------------------LP 2244
Query: 1033 SQGEVEREGESPAAGPPPQELV-EEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETE 1091
G V +P PPP LV P++PP + + PP P + +
Sbjct: 2245 VVGVVR---PAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLD 2301
Query: 1092 TEAEALQEKEQ 1102
+ EA ++ Q
Sbjct: 2302 EDGEASEDTPQ 2312
Score = 32.7 bits (73), Expect = 2.0
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 17/118 (14%)
Query: 647 TPAPVPPPEAPSPFRAPPFHPPG-PMP-SVG-----SMPSAGPM----------PSAGPM 689
TP P+ PEAP P P P P P +VG S+P P+ P P
Sbjct: 667 TPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726
Query: 690 PSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPP 747
S GP A+ P A L L P+L P P + E +A G+ P
Sbjct: 727 LSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLP 784
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 85.5 bits (210), Expect = 3e-16
Identities = 43/84 (51%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 794 GLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVP--- 850
G P PPPP G P AP P +PP+P EP P PG LPPPPPPPPP P
Sbjct: 539 GAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTD 598
Query: 851 GPVTLPPPQLVPEGTPGGGGPPAL 874
GPV PPP P P GG P AL
Sbjct: 599 GPVPPPPP---PPPPPPGGPPDAL 619
Score = 65.9 bits (159), Expect = 2e-10
Identities = 70/274 (25%), Positives = 89/274 (32%), Gaps = 44/274 (16%)
Query: 621 SEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSA 680
SE+ A+ P P PT P+ + E PG S+ +P A
Sbjct: 448 SESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVA 507
Query: 681 GPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPIL 740
PS G P+ G VP+ P P PG PP LPG + + P
Sbjct: 508 VATPSGGDAPTPG-VPTGSPSPDLAP--AAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQ 564
Query: 741 APSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPP 800
AP P PP G +P P PP PP
Sbjct: 565 APPLPGSPEPPPAPPLPGDLPPP--------------------------------PPPPP 592
Query: 801 PPPS--GATPPPIAPTGPPTASPPVPAKEEPEEL-PAAPGPLPPPPPPPPPVPGPVTLPP 857
PPP G PPP P PP PP EL P P P+ V L P
Sbjct: 593 PPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKP 652
Query: 858 PQLVPEGTPGGGGPPALEEDLTVININSSDEEEE 891
Q+ G L ++ + ++ SD EE+
Sbjct: 653 SQIT------GTVFTELNDEKVLQELDMSDFEEQ 680
Score = 48.9 bits (115), Expect = 3e-05
Identities = 67/248 (27%), Positives = 84/248 (33%), Gaps = 60/248 (24%)
Query: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE 932
AL ED N EE +E+ E + E E + E E++ + +E E
Sbjct: 386 ALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQ-LSQARKELETLR 444
Query: 933 EEFEEEEGELEEEEEEEDEE--------------EEEELEE---------------VEDL 963
E F E E E+ + EELEE +E L
Sbjct: 445 ERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEIL 504
Query: 964 EFGTA---GGE-----VEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTE 1015
A GG+ V G+P P P A P P + P P P P PGL E P
Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAP---PPPPPLPGLPSPQEAP--- 558
Query: 1016 EERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDK 1075
P+ P+A P G E P A P P +L P PP DG
Sbjct: 559 --------PSAPPQAPPLPGSPE----PPPAPPLPGDLPPPPPPPPPP----PGTDGPVP 602
Query: 1076 VQPPPETP 1083
PPP P
Sbjct: 603 PPPPPPPP 610
Score = 48.1 bits (113), Expect = 5e-05
Identities = 54/219 (24%), Positives = 79/219 (36%), Gaps = 27/219 (12%)
Query: 919 EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEF----GTAGGEVEE 974
E+ EE +E+ E + E E + E +++ + +E+E L TA G
Sbjct: 399 EHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMG-ASR 457
Query: 975 GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034
P P PPA P S +++ E E GL+ + PG ++ E LP
Sbjct: 458 RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGD----------AVSIEILPVA 507
Query: 1035 GEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP----ETPAEEEMET 1090
G++P G P +P E G+ PPP +P E
Sbjct: 508 VATPSGGDAPTPGVPTGS------PSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSA 561
Query: 1091 ETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPD 1129
+A L + A L D PP PPPP D
Sbjct: 562 PPQAPPLPGSPEPPPAPPLPG--DLPPPPPPPPPPPGTD 598
Score = 40.8 bits (94), Expect = 0.007
Identities = 29/89 (32%), Positives = 32/89 (35%), Gaps = 12/89 (13%)
Query: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE 1036
PPPP LP P E+PP P+ P PG EP D P P P
Sbjct: 543 PPPPPLPGLPSPQEAPPSAPPQAPPLPG----SPEPPPAPPLPGDLPPPPPPPPPPP--- 595
Query: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLL 1065
+G P PPP P PP L
Sbjct: 596 -GTDGPVPPPPPPP----PPPPGGPPDAL 619
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.133 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,974,287
Number of Sequences: 37866
Number of extensions: 5598568
Number of successful extensions: 284836
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2882
Number of HSP's successfully gapped in prelim test: 2472
Number of HSP's that attempted gapping in prelim test: 43662
Number of HSP's gapped (non-prelim): 86984
length of query: 1130
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1017
effective length of database: 13,968,660
effective search space: 14206127220
effective search space used: 14206127220
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.