Search of human proteins with 154813204

Search of human proteins with 154813204

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154813204 inhibin beta B subunit preproprotein [Homo
sapiens]
         (407 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]      852   0.0  
gi|4504699 inhibin beta A precursor [Homo sapiens]                    332   5e-91
gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]          218   8e-57
gi|13899338 activin beta E [Homo sapiens]                             181   1e-45
gi|5031613 growth differentiation factor 11 precursor [Homo sapi...   129   6e-30
gi|4885259 myostatin [Homo sapiens]                                   125   5e-29
gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi...   105   1e-22
gi|10190670 growth differentiation factor 3 precursor [Homo sapi...   100   3e-21
gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]       96   6e-20
gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa...    95   1e-19
gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa...    95   1e-19
gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa...    95   1e-19
gi|110349792 growth differentiation factor 1 [Homo sapiens]            93   5e-19
gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi...    90   3e-18
gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa...    89   9e-18
gi|145611428 bone morphogenetic protein 8A [Homo sapiens]              87   4e-17
gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sa...    86   8e-17
gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sap...    86   8e-17
gi|4826740 growth differentiation factor 10 precursor [Homo sapi...    84   2e-16
gi|48475062 growth differentiation factor 6 precursor [Homo sapi...    84   3e-16
gi|63025222 transforming growth factor, beta 1 [Homo sapiens]          82   9e-16
gi|4503969 growth differentiation factor 5 preproprotein [Homo s...    80   3e-15
gi|61835232 growth differentiation factor 7 preproprotein [Homo ...    79   6e-15
gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap...    77   2e-14
gi|222352098 nodal precursor [Homo sapiens]                            73   4e-13
gi|4507465 transforming growth factor, beta 3 [Homo sapiens]           72   1e-12
gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]      65   8e-11
gi|7705308 growth differentiation factor 2 [Homo sapiens]              65   1e-10
gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo ...    63   4e-10
gi|4507463 transforming growth factor, beta 2 isoform 2 [Homo sa...    63   4e-10

>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
          Length = 407

 Score =  852 bits (2200), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 1   MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG 60
           MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG
Sbjct: 1   MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG 60

Query: 61  FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR 120
           FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR
Sbjct: 61  FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR 120

Query: 121 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL 180
           VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL
Sbjct: 121 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL 180

Query: 181 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE 240
           YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE
Sbjct: 181 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE 240

Query: 241 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT 300
           RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT
Sbjct: 241 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT 300

Query: 301 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM 360
           NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM
Sbjct: 301 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM 360

Query: 361 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
           RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
Sbjct: 361 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407


>gi|4504699 inhibin beta A precursor [Homo sapiens]
          Length = 426

 Score =  332 bits (850), Expect = 5e-91
 Identities = 177/413 (42%), Positives = 254/413 (61%), Gaps = 56/413 (13%)

Query: 43  PPPGSPGGSQ-DTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKA 101
           P PGS G S    C SC     P+++     + +EAVK+HIL+ L ++ RP++T  VPKA
Sbjct: 22  PTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKA 81

Query: 102 AMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYF 161
           A++ A+RKLH GKV E+G VEI    G  +   +  E+ SEII+FAE+    ++R  L+F
Sbjct: 82  ALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAES---GTARKTLHF 138

Query: 162 FISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKV-YFQEQGH------------ 208
            IS EG+    V +A +WL+LK     + K +R + +V +  FQ+Q H            
Sbjct: 139 EISKEGSDLSVVERAEVWLFLK-----VPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAE 193

Query: 209 -----GDRWNMV--EKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVV 261
                G+R  ++  EK VD ++S WH FP++ +IQ L ++G+  L++ + C+ CQE    
Sbjct: 194 EVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGAS 253

Query: 262 PVFV-------------------------DPGEESHRPFVVVQARLG-DSRHRIRKRGLE 295
            V +                         +  E+SHRPF+++QAR   D  HR R+RGLE
Sbjct: 254 LVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLE 313

Query: 296 CDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVV 355
           CDG+ N+CC++QFF+ F+ IGWNDWIIAP+GY+ NYCEG CP+++AG  GS+ SFH+ V+
Sbjct: 314 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVI 373

Query: 356 NQYRMRGLNP-GTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
           N YRMRG +P   + SCC+PTKL  MSMLY+DD  NI+K+D+ NMIVEECGC+
Sbjct: 374 NHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS 426


>gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
          Length = 352

 Score =  218 bits (555), Expect = 8e-57
 Identities = 138/383 (36%), Positives = 203/383 (53%), Gaps = 47/383 (12%)

Query: 29  SPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQM 88
           +PT   TP A          GG    C +CGG     EL       L+  KR IL +L +
Sbjct: 13  APTTVATPRA----------GGQ---CPACGG--PTLELESQRELLLDLAKRSILDKLHL 57

Query: 89  RGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAE 148
             RP +   V +AA+ TAL+ LH   V +   +E            D +E+  EIISFAE
Sbjct: 58  TQRPTLNRPVSRAALRTALQHLHG--VPQGALLE------------DNREQECEIISFAE 103

Query: 149 TDGLASSRVRLYFFISNEGNQ-NLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQG 207
           T     ++ RL F  S++    +  V QASL  +++L        +   ++V+V      
Sbjct: 104 TGLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQL-----PSNTTWTLKVRVLVLGPH 158

Query: 208 HGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDP 267
           + +     +  +++  SGWH  PL    QA   +G   L L ++    Q   ++      
Sbjct: 159 NTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTLELVLEGQVAQSSVIL------ 212

Query: 268 GEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGY 327
           G  +HRPFV  + R+G  +H+I +RG++C G + +CCRQ+FF+DFR IGW+DWII P GY
Sbjct: 213 GGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGY 271

Query: 328 YGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMR---GLNPGTVNSCCIPTKLSTMSMLY 384
             N+C G CP ++AG+PG A+SFHTAV+N  +     G   G   SCC+PT    +S+LY
Sbjct: 272 AMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGG--GSCCVPTARRPLSLLY 329

Query: 385 FDDEYNIVKRDVPNMIVEECGCA 407
           +D + NIVK D+P+M+VE CGC+
Sbjct: 330 YDRDSNIVKTDIPDMVVEACGCS 352


>gi|13899338 activin beta E [Homo sapiens]
          Length = 350

 Score =  181 bits (459), Expect = 1e-45
 Identities = 126/367 (34%), Positives = 182/367 (49%), Gaps = 46/367 (12%)

Query: 50  GSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRK 109
           G+   C SCGG +   +  R     LE  K+ IL  L +  RP ITH  P+AA+  ALR+
Sbjct: 21  GTGSVCPSCGGSKLAPQAERAL--VLELAKQQILDGLHLTSRPRITHPPPQAALTRALRR 78

Query: 110 LHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAE-TDGLASSRVRLYFFISNEGN 168
           L  G V               +PG +G+E    +ISFA  TD  ++    L F +S   +
Sbjct: 79  LQPGSV---------------APG-NGEE----VISFATVTDSTSAYSSLLTFHLSTPRS 118

Query: 169 QNLFVVQASLWLY-LKLLPYVL-----EKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLK 222
            +L+   A LWL+ L  LP  L       G RR+ +          G R  + E  +   
Sbjct: 119 HHLY--HARLWLHVLPTLPGTLCLRIFRWGPRRRRQ----------GSRTLLAEHHIT-- 164

Query: 223 RSGWHTFPLTEAIQALFERGERRLNLDVQ-CDSCQELAVVPVFVDPGEESHRPFVVVQAR 281
             GWHT  L  +     + G  +L LD +  +    +   P  +       +PF+ ++ R
Sbjct: 165 NLGWHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIR 224

Query: 282 LGD-SRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYL 340
             +    R R+R   C+  T LCCR+  ++DF+ +GW DWI+ P GY  NYC G CP +L
Sbjct: 225 ANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHL 284

Query: 341 AGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMI 400
           AG PG A+SFH+AV +  +     P +  SCC+PT    +S+LY D   N+VK DVP+M+
Sbjct: 285 AGSPGIAASFHSAVFSLLKANNPWPAS-TSCCVPTARRPLSLLYLDHNGNVVKTDVPDMV 343

Query: 401 VEECGCA 407
           VE CGC+
Sbjct: 344 VEACGCS 350


>gi|5031613 growth differentiation factor 11 precursor [Homo
           sapiens]
          Length = 407

 Score =  129 bits (323), Expect = 6e-30
 Identities = 115/417 (27%), Positives = 180/417 (43%), Gaps = 51/417 (12%)

Query: 6   GRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPE 65
           G A  AA     AA  +G    G  +  P P+  P P          D C  C   +   
Sbjct: 27  GPAAAAAAAAAAAAAGVG----GERSSRPAPSVAPEP----------DGCPVCVWRQHSR 72

Query: 66  ELGRVDGDFLEAVKRHILSRLQMRGRPNITHAV-----PKAAMVTALRKLHAGKVREDGR 120
           EL       LE++K  ILS+L+++  PNI+  V     PKA  +  +  LH  +      
Sbjct: 73  ELR------LESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQP 126

Query: 121 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL 180
            +    D + +          E     +TDG   S +  +F  S +      V++A LW+
Sbjct: 127 EDFLEEDEYHATTETVISMAQETDPAVQTDG---SPLCCHFHFSPKVMFTK-VLKAQLWV 182

Query: 181 YLKLLPY---VLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLK---RSG-WHTFPLTE 233
           YL+ +P    V  +  R K          G G R ++  + + ++   RSG W +    +
Sbjct: 183 YLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQ 242

Query: 234 AIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRG 293
            + + F + +    +++         +    + PG E   PF+ ++      R R R  G
Sbjct: 243 VLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENTKRSR-RNLG 301

Query: 294 LECDGRTN--LCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCP-AYLAGVPGSASSF 350
           L+CD  ++   CCR    +DF   GW DWIIAP  Y  NYC G C   ++   P      
Sbjct: 302 LDCDEHSSESRCCRYPLTVDFEAFGW-DWIIAPKRYKANYCSGQCEYMFMQKYP------ 354

Query: 351 HTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
           HT +V Q   RG    +   CC PTK+S ++MLYF+D+  I+   +P M+V+ CGC+
Sbjct: 355 HTHLVQQANPRG----SAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS 407


>gi|4885259 myostatin [Homo sapiens]
          Length = 375

 Score =  125 bits (315), Expect = 5e-29
 Identities = 103/349 (29%), Positives = 166/349 (47%), Gaps = 42/349 (12%)

Query: 75  LEAVKRHILSRLQMRGRPNITHAV-----PKAAMVTALRKLHAGKVREDGRVEIPHLDGH 129
           +EA+K  ILS+L++   PNI+  V     PKA  +  L   +  +  +     +   D H
Sbjct: 53  IEAIKIQILSKLRLETAPNISKDVIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYH 112

Query: 130 ASPGADGQERVSEIISF-AETDGL--ASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLP 186
           A+           II+   E+D L     + +  FF  +   Q   VV+A LW+YL+   
Sbjct: 113 AT--------TETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLR--- 161

Query: 187 YVLEKGSRRKVRVKVYFQEQGHGDRWNMVEK-RVDLKRSG--WHTFPLTEAIQALFERGE 243
             +E  +   V++    +    G R+  +   ++D+      W +  +   +Q   ++ E
Sbjct: 162 -PVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPE 220

Query: 244 RRLNLDVQC--DSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT- 300
             L ++++   ++  +LAV   F  PGE+   PF+ V+      R R R  GL+CD  + 
Sbjct: 221 SNLGIEIKALDENGHDLAVT--FPGPGEDGLNPFLEVKVTDTPKRSR-RDFGLDCDEHST 277

Query: 301 -NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCP-AYLAGVPGSASSFHTAVVNQY 358
            + CCR    +DF   GW DWIIAP  Y  NYC G C   +L   P      HT +V+Q 
Sbjct: 278 ESRCCRYPLTVDFEAFGW-DWIIAPKRYKANYCSGECEFVFLQKYP------HTHLVHQA 330

Query: 359 RMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
             RG    +   CC PTK+S ++MLYF+ +  I+   +P M+V+ CGC+
Sbjct: 331 NPRG----SAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS 375


>gi|4557369 bone morphogenetic protein 2 preproprotein [Homo
           sapiens]
          Length = 396

 Score =  105 bits (261), Expect = 1e-22
 Identities = 88/355 (24%), Positives = 148/355 (41%), Gaps = 28/355 (7%)

Query: 73  DFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASP 132
           + L   +  +LS   ++ RP  +        +  L + H+G   + G     H    A+ 
Sbjct: 48  EVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG---QPGSPAPDHRLERAAS 104

Query: 133 GADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKG 192
            A+         S  E    +    R +FF  +      F+  A L ++ + +   L   
Sbjct: 105 RANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNN 164

Query: 193 SRRKVRVKVY--FQEQGHGDRWNMVE----KRVDLKRSGWHTFPLTEAIQALFERGERRL 246
           S    R+ +Y   +      ++ +      + V+   S W +F +T A+     +G    
Sbjct: 165 SSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANH 224

Query: 247 NLDVQCDSCQELAVVP-----VFVDPGEESH-----RPFVVVQARLGDSR--HRIRKRGL 294
              V+    +E   V      +     ++ H     RP +V     G     H+  KR  
Sbjct: 225 GFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQA 284

Query: 295 ECDGRTNL---CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFH 351
           +   R  L   C R   ++DF  +GWNDWI+AP GY+  YC G CP  LA      +S +
Sbjct: 285 KHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLA---DHLNSTN 341

Query: 352 TAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
            A+V Q  +  +N     +CC+PT+LS +SMLY D+   +V ++  +M+VE CGC
Sbjct: 342 HAIV-QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGC 395


>gi|10190670 growth differentiation factor 3 precursor [Homo
           sapiens]
          Length = 364

 Score =  100 bits (248), Expect = 3e-21
 Identities = 48/106 (45%), Positives = 67/106 (63%), Gaps = 4/106 (3%)

Query: 301 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM 360
           NLC R Q FI+FR +GW+ WIIAP G+  NYC G CP  L  +  ++S++      Q  M
Sbjct: 262 NLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLT-ISLNSSNY---AFMQALM 317

Query: 361 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
             ++P    + CIPTKLS +SMLY D+  N++ R   +M+V+ECGC
Sbjct: 318 HAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363


>gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]
          Length = 431

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 68/255 (26%), Positives = 105/255 (41%), Gaps = 39/255 (15%)

Query: 187 YVLEKGSRRKVRVKVYFQEQGH----GDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERG 242
           Y+ E+      R+ VY   Q H     D + +  + +     GW  F +T          
Sbjct: 180 YIRERFDNETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNP 239

Query: 243 ERRLNLDVQCDSCQELAVVPVFVD----PGEESHRPFVVV----------QARLGDSRHR 288
              L L +  ++    ++ P         G ++ +PF+V             R   S+ R
Sbjct: 240 RHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQR 299

Query: 289 IRKRGLECDGRTNL----------------CCRQQFFIDFRLIGWNDWIIAPTGYYGNYC 332
            + R      +  L                C + + ++ FR +GW DWIIAP GY   YC
Sbjct: 300 SQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYC 359

Query: 333 EGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTV-NSCCIPTKLSTMSMLYFDDEYNI 391
           EG C   L     + +  H  V  Q  +  +NP TV   CC PT+L+ +S+LYFDD  N+
Sbjct: 360 EGECAFPLNSYMNATN--HAIV--QTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNV 415

Query: 392 VKRDVPNMIVEECGC 406
           + +   NM+V  CGC
Sbjct: 416 ILKKYRNMVVRACGC 430


>gi|157276597 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 44/104 (42%), Positives = 62/104 (59%), Gaps = 4/104 (3%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRG 362
           C R   ++DF  +GWNDWI+AP GY   YC G CP  LA      +S + A+V Q  +  
Sbjct: 308 CRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLA---DHLNSTNHAIV-QTLVNS 363

Query: 363 LNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           +N     +CC+PT+LS +SMLY D+   +V ++   M+VE CGC
Sbjct: 364 VNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407


>gi|157276595 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 44/104 (42%), Positives = 62/104 (59%), Gaps = 4/104 (3%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRG 362
           C R   ++DF  +GWNDWI+AP GY   YC G CP  LA      +S + A+V Q  +  
Sbjct: 308 CRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLA---DHLNSTNHAIV-QTLVNS 363

Query: 363 LNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           +N     +CC+PT+LS +SMLY D+   +V ++   M+VE CGC
Sbjct: 364 VNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407


>gi|157276593 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 44/104 (42%), Positives = 62/104 (59%), Gaps = 4/104 (3%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRG 362
           C R   ++DF  +GWNDWI+AP GY   YC G CP  LA      +S + A+V Q  +  
Sbjct: 308 CRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLA---DHLNSTNHAIV-QTLVNS 363

Query: 363 LNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           +N     +CC+PT+LS +SMLY D+   +V ++   M+VE CGC
Sbjct: 364 VNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407


>gi|110349792 growth differentiation factor 1 [Homo sapiens]
          Length = 372

 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 42/112 (37%), Positives = 66/112 (58%), Gaps = 5/112 (4%)

Query: 298 GRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSC--PAYLAGVPGSASSFHTAVV 355
           G    C  ++ ++ FR +GW+ W+IAP G+  NYC+G C  P  L+G  G  +  H  + 
Sbjct: 262 GPGGACRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSGSGGPPALNHAVL- 320

Query: 356 NQYRMRGLNPGTVN-SCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
            +  M    PG  +  CC+P +LS +S+L+FD+  N+V R   +M+V+ECGC
Sbjct: 321 -RALMHAAAPGAADLPCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGC 371


>gi|4502425 bone morphogenetic protein 6 preproprotein [Homo
           sapiens]
          Length = 513

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 43/105 (40%), Positives = 61/105 (58%), Gaps = 5/105 (4%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRG 362
           C + + ++ F+ +GW DWIIAP GY  NYC+G C   L     + +  H  V  Q  +  
Sbjct: 412 CRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATN--HAIV--QTLVHL 467

Query: 363 LNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           +NP  V   CC PTKL+ +S+LYFDD  N++ +   NM+V  CGC
Sbjct: 468 MNPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 512


>gi|126507087 bone morphogenetic protein 3 preproprotein [Homo
           sapiens]
          Length = 472

 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 41/105 (39%), Positives = 61/105 (58%), Gaps = 4/105 (3%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSAS-SFHTAVVNQYRMR 361
           C R+   +DF  IGW++WII+P  +   YC G+C   +   P S   S H  + +  R  
Sbjct: 370 CARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPM---PKSLKPSNHATIQSIVRAV 426

Query: 362 GLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           G+ PG    CC+P K+S++S+L+FD+  N+V +  PNM VE C C
Sbjct: 427 GVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCAC 471


>gi|145611428 bone morphogenetic protein 8A [Homo sapiens]
          Length = 402

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 41/106 (38%), Positives = 59/106 (55%), Gaps = 5/106 (4%)

Query: 302 LCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMR 361
           +C R + ++ F+ +GW DW+IAP GY   YCEG C   L     S  +     + Q  + 
Sbjct: 300 VCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPL----DSCMNATNHAILQSLVH 355

Query: 362 GLNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
            + P  V  +CC PTKLS  S+LY+D   N++ R   NM+V+ CGC
Sbjct: 356 LMKPNAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|29571106 bone morphogenetic protein 8B preproprotein [Homo
           sapiens]
          Length = 402

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 41/106 (38%), Positives = 59/106 (55%), Gaps = 5/106 (4%)

Query: 302 LCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMR 361
           +C R + ++ F+ +GW DW+IAP GY   YCEG C   L     S  +     + Q  + 
Sbjct: 300 VCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPL----DSCMNATNHAILQSLVH 355

Query: 362 GLNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
            + P  V  +CC PTKLS  S+LY+D   N++ R   NM+V+ CGC
Sbjct: 356 LMMPDAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|10835091 bone morphogenetic protein 5 preproprotein [Homo
           sapiens]
          Length = 454

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 42/105 (40%), Positives = 59/105 (56%), Gaps = 5/105 (4%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRG 362
           C + + ++ FR +GW DWIIAP GY   YC+G C   L     + +  H  V  Q  +  
Sbjct: 353 CKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATN--HAIV--QTLVHL 408

Query: 363 LNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           + P  V   CC PTKL+ +S+LYFDD  N++ +   NM+V  CGC
Sbjct: 409 MFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGC 453


>gi|4826740 growth differentiation factor 10 precursor [Homo
           sapiens]
          Length = 478

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 35/105 (33%), Positives = 60/105 (57%), Gaps = 2/105 (1%)

Query: 302 LCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMR 361
           +C R+   +DF  IGWN+WII+P  +   YC G+C   +  +   ++  H  + +  R  
Sbjct: 375 VCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSN--HATIQSIVRAV 432

Query: 362 GLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           G+ PG    CC+P K++++ +L+ D+  N+V +  PNM V+ C C
Sbjct: 433 GIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCAC 477


>gi|48475062 growth differentiation factor 6 precursor [Homo
           sapiens]
          Length = 455

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 41/105 (39%), Positives = 62/105 (59%), Gaps = 5/105 (4%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRG 362
           C ++   ++F+ +GW+DWIIAP  Y   +CEG C   L          + A++ Q  M  
Sbjct: 354 CSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRS---HLEPTNHAII-QTLMNS 409

Query: 363 LNPG-TVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           ++PG T  SCC+PTKL+ +S+LY D   N+V +   +M+VE CGC
Sbjct: 410 MDPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGC 454


>gi|63025222 transforming growth factor, beta 1 [Homo sapiens]
          Length = 390

 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 97/395 (24%), Positives = 154/395 (38%), Gaps = 59/395 (14%)

Query: 45  PGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMV 104
           PG P     TC +        ++  V    +EA++  ILS+L++   P+     P     
Sbjct: 23  PGRPAAGLSTCKTI-------DMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPE 75

Query: 105 TALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAET-DGLASSRVRLYFFI 163
             L   ++ + R  G    P  +  A   A    RV  + +  E  D    S   +Y F 
Sbjct: 76  AVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFF 135

Query: 164 SNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVK------VYFQEQGHGDRWNMVEK 217
           +    +                P +L +   R +R+K      V   ++   + W  +  
Sbjct: 136 NTSELREAVPE-----------PVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSN 184

Query: 218 RVDLKRSG--WHTFPLTEAIQALFERGER----RLNLDVQCDSCQELAVVPVF-VDPGEE 270
           R+        W +F +T  ++    RG      RL+    CDS      V +     G  
Sbjct: 185 RLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRR 244

Query: 271 S--------HRPFVVVQA-------RLGDSRHRIRKRGLECDGRTNL-CCRQQFFIDFRL 314
                    +RPF+++ A        L  SRHR       C   T   CC +Q +IDFR 
Sbjct: 245 GDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRK 304

Query: 315 -IGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPG-TVNSCC 372
            +GW  WI  P GY+ N+C G CP Y+  +    S    A+ NQ+     NPG +   CC
Sbjct: 305 DLGWK-WIHEPKGYHANFCLGPCP-YIWSLDTQYSKV-LALYNQH-----NPGASAAPCC 356

Query: 373 IPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
           +P  L  + ++Y+      V++ + NMIV  C C+
Sbjct: 357 VPQALEPLPIVYYVGRKPKVEQ-LSNMIVRSCKCS 390


>gi|4503969 growth differentiation factor 5 preproprotein [Homo
           sapiens]
          Length = 501

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 40/105 (38%), Positives = 61/105 (58%), Gaps = 5/105 (4%)

Query: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRG 362
           C R+   ++F+ +GW+DWIIAP  Y   +CEG C   L          + AV+ Q  M  
Sbjct: 400 CSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRS---HLEPTNHAVI-QTLMNS 455

Query: 363 LNP-GTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           ++P  T  +CC+PT+LS +S+L+ D   N+V +   +M+VE CGC
Sbjct: 456 MDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGC 500


>gi|61835232 growth differentiation factor 7 preproprotein [Homo
           sapiens]
          Length = 450

 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 6/116 (5%)

Query: 292 RGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFH 351
           RG    GR+  C R+   +DF+ +GW+DWIIAP  Y   +CEG C   L          +
Sbjct: 339 RGHGRRGRSR-CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLR---SHLEPTN 394

Query: 352 TAVVNQYRMRGLNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
            A++ Q  +  + P     SCC+P +LS +S+LY D   N+V +   +M+VE CGC
Sbjct: 395 HAII-QTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449


>gi|7656928 bone morphogenetic protein 10 preproprotein [Homo
           sapiens]
          Length = 424

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 16/143 (11%)

Query: 267 PGEESHRPFVVVQAR---LGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIA 323
           PGEE+     ++Q R   + DS  RIR+     + + N C R   +IDF+ IGW+ WIIA
Sbjct: 294 PGEEA-----LLQMRSNIIYDSTARIRR-----NAKGNYCKRTPLYIDFKEIGWDSWIIA 343

Query: 324 PTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSML 383
           P GY    C G C   LA       + H  +     ++     +  +CC+PTKL  +S+L
Sbjct: 344 PPGYEAYECRGVCNYPLA--EHLTPTKHAIIQALVHLKNSQKAS-KACCVPTKLEPISIL 400

Query: 384 YFDDEYNIVKRDVPNMIVEECGC 406
           Y D      K     M V ECGC
Sbjct: 401 YLDKGVVTYKFKYEGMAVSECGC 423


>gi|222352098 nodal precursor [Homo sapiens]
          Length = 347

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 44/120 (36%), Positives = 58/120 (48%), Gaps = 10/120 (8%)

Query: 290 RKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASS 349
           R R      R+ LC + +F +DF LIGW  WII P  Y    CEG CP  +         
Sbjct: 234 RHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPV------GEE 287

Query: 350 FHTA--VVNQYRMRGLNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
           FH       Q  ++   P  V ++CC P K   +SMLY D+   ++     +MIVEECGC
Sbjct: 288 FHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNG-RVLLDHHKDMIVEECGC 346


>gi|4507465 transforming growth factor, beta 3 [Homo sapiens]
          Length = 412

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 11/107 (10%)

Query: 303 CCRQQFFIDFRL-IGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMR 361
           CC +  +IDFR  +GW  W+  P GYY N+C G CP YL     SA + H+ V+  Y   
Sbjct: 315 CCVRPLYIDFRQDLGWK-WVHEPKGYYANFCSGPCP-YLR----SADTTHSTVLGLYNT- 367

Query: 362 GLNP-GTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
            LNP  + + CC+P  L  +++LY+      V++ + NM+V+ C C+
Sbjct: 368 -LNPEASASPCCVPQDLEPLTILYYVGRTPKVEQ-LSNMVVKSCKCS 412


>gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]
          Length = 392

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 51/219 (23%), Positives = 89/219 (40%), Gaps = 36/219 (16%)

Query: 221 LKRSGWHTFPLTEAIQALF--ERGERRLNLDVQCD--------------SCQELAVVPVF 264
           L  + W    +T+ +Q  F   +G R L L   C               S  ++A + ++
Sbjct: 176 LMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWHGTSSLDIAFLLLY 235

Query: 265 VDPGEESHRPFVVVQARLGD--SRHRIRKRGLECDG---------------RTNLCCRQQ 307
            +   +S R    +   + +   R  + +R  + DG                 N C    
Sbjct: 236 FNDTHKSIRKAKFLPRGMEEFMERESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHP 295

Query: 308 FFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGT 367
           F I FR +GW+ WIIAP  Y  NYC+G+C   L  +    +S + A++     + ++   
Sbjct: 296 FQISFRQLGWDHWIIAPPFYTPNYCKGTC---LRVLRDGLNSPNHAIIQNLINQLVDQSV 352

Query: 368 VNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406
               C+P K   +S+L  +   +I+ ++   MI E C C
Sbjct: 353 PRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTC 391


>gi|7705308 growth differentiation factor 2 [Homo sapiens]
          Length = 429

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 48/144 (33%), Positives = 65/144 (45%), Gaps = 12/144 (8%)

Query: 266 DPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT 325
           + GE SH          G +  R RKR     G  + C +    ++F  IGW+ WIIAP 
Sbjct: 294 EAGESSHEEDTDGHVAAGSTLAR-RKRSA---GAGSHCQKTSLRVNFEDIGWDSWIIAPK 349

Query: 326 GYYGNYCEGSCPAYLAG--VPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSML 383
            Y    C+G C   LA    P   +   T V  ++  +        +CC+PTKLS +S+L
Sbjct: 350 EYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTK-----VGKACCVPTKLSPISVL 404

Query: 384 YFDD-EYNIVKRDVPNMIVEECGC 406
           Y DD     +K     M V ECGC
Sbjct: 405 YKDDMGVPTLKYHYEGMSVAECGC 428


>gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 37/107 (34%), Positives = 62/107 (57%), Gaps = 11/107 (10%)

Query: 303 CCRQQFFIDF-RLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMR 361
           CC +  +IDF R +GW  WI  P GY  N+C G+CP YL     S+ + H+ V++ Y   
Sbjct: 345 CCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGACP-YL----WSSDTQHSRVLSLYNT- 397

Query: 362 GLNP-GTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
            +NP  + + CC+   L  +++LY+  +   +++ + NMIV+ C C+
Sbjct: 398 -INPEASASPCCVSQDLEPLTILYYIGKTPKIEQ-LSNMIVKSCKCS 442


>gi|4507463 transforming growth factor, beta 2 isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 37/107 (34%), Positives = 62/107 (57%), Gaps = 11/107 (10%)

Query: 303 CCRQQFFIDF-RLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMR 361
           CC +  +IDF R +GW  WI  P GY  N+C G+CP YL     S+ + H+ V++ Y   
Sbjct: 317 CCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGACP-YL----WSSDTQHSRVLSLYNT- 369

Query: 362 GLNP-GTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407
            +NP  + + CC+   L  +++LY+  +   +++ + NMIV+ C C+
Sbjct: 370 -INPEASASPCCVSQDLEPLTILYYIGKTPKIEQ-LSNMIVKSCKCS 414


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,680,263
Number of Sequences: 37866
Number of extensions: 1170038
Number of successful extensions: 31621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 612
Number of HSP's successfully gapped in prelim test: 326
Number of HSP's that attempted gapping in prelim test: 16817
Number of HSP's gapped (non-prelim): 10369
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.