BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] (224 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 464 e-131 gi|6912276 cysteine-rich hydrophobic domain 2 [Homo sapiens] 285 2e-77 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 68 6e-12 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 68 6e-12 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 68 6e-12 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 68 6e-12 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 68 6e-12 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 68 6e-12 gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 68 6e-12 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 68 6e-12 gi|17975763 myelin transcription factor 1 [Homo sapiens] 63 2e-10 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 59 3e-09 gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 57 2e-08 gi|58761548 tau tubulin kinase 1 [Homo sapiens] 57 2e-08 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 57 2e-08 gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 57 2e-08 gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 56 3e-08 gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 56 3e-08 gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 56 3e-08 gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 56 3e-08 gi|118600967 shroom family member 4 [Homo sapiens] 55 6e-08 gi|4503257 death-domain associated protein isoform a [Homo sapiens] 54 1e-07 gi|215422388 death-domain associated protein isoform a [Homo sap... 54 1e-07 gi|215422366 death-domain associated protein isoform b [Homo sap... 54 1e-07 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 54 1e-07 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 54 1e-07 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 54 1e-07 gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 54 1e-07 gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 54 1e-07 gi|28274705 family with sequence similarity 9, member A [Homo sa... 54 1e-07 >gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] Length = 224 Score = 464 bits (1193), Expect = e-131 Identities = 224/224 (100%), Positives = 224/224 (100%) Query: 1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE Sbjct: 1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60 Query: 61 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP 120 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP Sbjct: 61 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP 120 Query: 121 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW 180 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW Sbjct: 121 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW 180 Query: 181 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD 224 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD Sbjct: 181 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD 224 >gi|6912276 cysteine-rich hydrophobic domain 2 [Homo sapiens] Length = 165 Score = 285 bits (729), Expect = 2e-77 Identities = 131/168 (77%), Positives = 149/168 (88%), Gaps = 7/168 (4%) Query: 57 EEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTG 116 +E EEEE+EE A EE L +Y+PDPV+VRG+GH+TVFGLSNKF++EFPS LTG Sbjct: 5 DEIYEEEEDEERA-------LEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTG 57 Query: 117 KVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQK 176 KVAPEEFK SI RVN+CLKK LPVNV+WLLCGCLCCCCTLGCS+WPVICL+KRTRRSI+K Sbjct: 58 KVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEK 117 Query: 177 LIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD 224 L+EWENNRLYHKL LHW+L+KRKCET+NMMEYVILIEFLPK PIFRPD Sbjct: 118 LLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD 165 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 245 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 304 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 305 EEEEEEETGSNSEEASEQ 322 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 272 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 319 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 320 SEQSAEEVSEEEM 332 Score = 30.0 bits (66), Expect = 1.7 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 302 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 361 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 362 AEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLP---ALQGCRSVEEFQCLNR 418 Query: 106 FD 107 + Sbjct: 419 IE 420 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 315 EEEEEEETGSNSEEASEQ 332 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 282 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 329 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 330 SEQSAEEVSEEEM 342 Score = 30.0 bits (66), Expect = 1.7 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 312 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 371 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 372 AEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLP---ALQGCRSVEEFQCLNR 428 Query: 106 FD 107 + Sbjct: 429 IE 430 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 246 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 305 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 306 EEEEEEETGSNSEEASEQ 323 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 273 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 320 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 321 SEQSAEEVSEEEM 333 Score = 30.8 bits (68), Expect = 0.98 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 303 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 362 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 363 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 419 Query: 106 FD 107 + Sbjct: 420 IE 421 Score = 27.7 bits (60), Expect = 8.3 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 10/82 (12%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEE-----EEEEEEEEEEEEEEEE 66 D++ + EE++ A S V D++ E++ E+E E E + EE+ Sbjct: 71 DSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ 130 Query: 67 EEAP-----PPPRVVSEEHLRR 83 ++A R ++ EH RR Sbjct: 131 DKARREWERQKRREMAREHSRR 152 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 315 EEEEEEETGSNSEEASEQ 332 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 282 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 329 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 330 SEQSAEEVSEEEM 342 Score = 30.8 bits (68), Expect = 0.98 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 312 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 371 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 372 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 428 Query: 106 FD 107 + Sbjct: 429 IE 430 Score = 27.7 bits (60), Expect = 8.3 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 10/82 (12%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEE-----EEEEEEEEEEEEEEEE 66 D++ + EE++ A S V D++ E++ E+E E E + EE+ Sbjct: 71 DSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ 130 Query: 67 EEAP-----PPPRVVSEEHLRR 83 ++A R ++ EH RR Sbjct: 131 DKARREWERQKRREMAREHSRR 152 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 223 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 282 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 283 EEEEEEETGSNSEEASEQ 300 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 250 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 297 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 298 SEQSAEEVSEEEM 310 Score = 30.8 bits (68), Expect = 0.98 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 280 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 339 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 340 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 396 Query: 106 FD 107 + Sbjct: 397 IE 398 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 212 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 271 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 272 EEEEEEETGSNSEEASEQ 289 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 239 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 286 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 287 SEQSAEEVSEEEM 299 Score = 30.8 bits (68), Expect = 0.98 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 269 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 328 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 329 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 385 Query: 106 FD 107 + Sbjct: 386 IE 387 Score = 27.7 bits (60), Expect = 8.3 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 10/82 (12%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEE-----EEEEEEEEEEEEEEEE 66 D++ + EE++ A S V D++ E++ E+E E E + EE+ Sbjct: 37 DSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ 96 Query: 67 EEAP-----PPPRVVSEEHLRR 83 ++A R ++ EH RR Sbjct: 97 DKARREWERQKRREMAREHSRR 118 >gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3 [Homo sapiens] Length = 526 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 61 EEEEEEETGSNSEEASEQ 78 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 28 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 75 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 76 SEQSAEEVSEEEM 88 Score = 30.8 bits (68), Expect = 0.98 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 58 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 117 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 118 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 174 Query: 106 FD 107 + Sbjct: 175 IE 176 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 68.2 bits (165), Expect = 6e-12 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61 M E D +S+L++ + E TSS+ SS+ S SG +++EE+EEEEE EE EEEEEE Sbjct: 257 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 316 Query: 62 EEEEEEEAPPPPRVVSEE 79 EEEEEEE SE+ Sbjct: 317 EEEEEEETGSNSEEASEQ 334 Score = 50.4 bits (119), Expect = 1e-06 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + SE EEEEEEE S+ EE EEEEEEEEEEEEE EE Sbjct: 284 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 331 Query: 69 APPPPRVVSEEHL 81 + VSEE + Sbjct: 332 SEQSAEEVSEEEM 344 Score = 30.8 bits (68), Expect = 0.98 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55 E EEEEEEE S+S +S S ++E E+EE E E Sbjct: 314 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 373 Query: 56 -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105 EEE E E + ++P + ++ L +Y P ++G + F N+ Sbjct: 374 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 430 Query: 106 FD 107 + Sbjct: 431 IE 432 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 62.8 bits (151), Expect = 2e-10 Identities = 33/80 (41%), Positives = 42/80 (52%) Query: 17 LEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVV 76 LE+ EE++ S +++EE+EEE+EEEEEEEEEEEEEEEEE Sbjct: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299 Query: 77 SEEHLRRYAPDPVLVRGAGH 96 EE APD + H Sbjct: 300 EEEEEEEAAPDVIFQEDTSH 319 Score = 62.0 bits (149), Expect = 4e-10 Identities = 35/80 (43%), Positives = 44/80 (55%), Gaps = 4/80 (5%) Query: 14 ISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPP 73 +S EE+EEEE +++EE+EEEEEEEEEEEEEEEEEEEEE P Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEE----EEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310 Query: 74 RVVSEEHLRRYAPDPVLVRG 93 + E+ A +RG Sbjct: 311 VIFQEDTSHTSAQKAPELRG 330 Score = 47.0 bits (110), Expect = 1e-05 Identities = 26/68 (38%), Positives = 35/68 (51%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71 + + E+ E ++ S ++S S EEE+EEEEEEEEEEEE+EEEE Sbjct: 222 EEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEE 281 Query: 72 PPRVVSEE 79 EE Sbjct: 282 EEEEEEEE 289 Score = 45.1 bits (105), Expect = 5e-05 Identities = 28/71 (39%), Positives = 34/71 (47%), Gaps = 9/71 (12%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEE---------DEEEEEEEEEEEEEEEEEEEEE 68 + EE E T S S+ +E +EE+EEEEEEEEEEEE+EEEEE Sbjct: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279 Query: 69 APPPPRVVSEE 79 EE Sbjct: 280 EEEEEEEEEEE 290 Score = 43.5 bits (101), Expect = 1e-04 Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 7/68 (10%) Query: 10 EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE-------EEEEE 62 E D E EEEEEEE +++EE+EEEEEEEEEE +E+ Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318 Query: 63 EEEEEEAP 70 ++AP Sbjct: 319 HTSAQKAP 326 Score = 35.8 bits (81), Expect = 0.030 Identities = 19/64 (29%), Positives = 28/64 (43%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75 E EEE+EEE +++EE+EEEEEE + +E+ A P + Sbjct: 269 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328 Query: 76 VSEE 79 E Sbjct: 329 RGPE 332 Score = 30.4 bits (67), Expect = 1.3 Identities = 15/52 (28%), Positives = 26/52 (50%) Query: 17 LEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 ++ E+ EE ++ S +D +E +++ EEE+EEEEEE Sbjct: 216 IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEE 267 Score = 29.6 bits (65), Expect = 2.2 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%) Query: 15 SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEE 56 S L EEE EE S P++ S S DD+E EE EE + Sbjct: 738 SRLREEEPEE-----SEPAAHSFASSEADDQEVSEENFEERK 774 Score = 29.3 bits (64), Expect = 2.8 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 24/74 (32%) Query: 16 ELEEEEEEEAA--------TSSSSPSSSSSVSGPD----------------DDEEDEEEE 51 E EEEEEEEAA TS +S + + GP+ DD++DE+ Sbjct: 298 EEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTH 357 Query: 52 EEEEEEEEEEEEEE 65 + +E E ++ Sbjct: 358 SRKSTVTDESEMQD 371 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 58.9 bits (141), Expect = 3e-09 Identities = 31/66 (46%), Positives = 36/66 (54%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75 EL E EA G D +EE+EEEEE+EEEEEEEE+EEEEEE Sbjct: 832 ELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEK 891 Query: 76 VSEEHL 81 +EE L Sbjct: 892 GNEEPL 897 Score = 49.7 bits (117), Expect = 2e-06 Identities = 24/54 (44%), Positives = 32/54 (59%) Query: 15 SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +E +E E + + G D + +EEEEEEEE+EEEEEEEE+EEE Sbjct: 828 TESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE 881 Score = 47.8 bits (112), Expect = 8e-06 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDD----DEEDEEEEEEEEEEEEEEEEEEEEEAPPPP 73 E E E + ++ + + + G +D D D EEEEEEEEE+EEEEEEEE+E Sbjct: 825 EGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEE 884 Query: 74 RVVSEE 79 EE Sbjct: 885 EEEEEE 890 Score = 47.4 bits (111), Expect = 1e-05 Identities = 28/59 (47%), Positives = 33/59 (55%), Gaps = 20/59 (33%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAP 70 D+ E EEEEE+E EE+EEEE+EEEEEEEEEEEE+ E P Sbjct: 858 DSEEEEEEEEEQE--------------------EEEEEEEQEEEEEEEEEEEEKGNEEP 896 Score = 44.3 bits (103), Expect = 9e-05 Identities = 24/71 (33%), Positives = 34/71 (47%) Query: 19 EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSE 78 E E +E + + + + D D + EEEEEEEEE+EEEEEEE E Sbjct: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEE 886 Query: 79 EHLRRYAPDPV 89 E + +P+ Sbjct: 887 EEEEKGNEEPL 897 Score = 35.4 bits (80), Expect = 0.040 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 7/71 (9%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEE-------EEEEEEEEEEEEEEE 68 E+ E+ E + S S + + DE+ E+ + EEEEEEEEE+EEE Sbjct: 813 EIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEE 872 Query: 69 APPPPRVVSEE 79 + EE Sbjct: 873 EEEEEQEEEEE 883 Score = 30.8 bits (68), Expect = 0.98 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 4/55 (7%) Query: 15 SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69 SE EEEEEEE +++EE+EEE+ EE + E +++A Sbjct: 859 SEEEEEEEEEQEEEEEEEEQEEE----EEEEEEEEEKGNEEPLSLDWPETRQKQA 909 Score = 28.9 bits (63), Expect = 3.7 Identities = 16/51 (31%), Positives = 22/51 (43%) Query: 19 EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69 E E EE + + P EE E+E E E + + E E+E E A Sbjct: 766 EGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHA 816 Score = 28.1 bits (61), Expect = 6.3 Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 10 EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 E +T E E EE+ T + G ++ EDE E E + + E E+E E E Sbjct: 760 EGETAGEGETEEKSGGETQPEG-EGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAE 817 >gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sapiens] Length = 528 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/68 (47%), Positives = 39/68 (57%), Gaps = 11/68 (16%) Query: 5 LPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEE 64 LP + +L E +EE+ SS +EE+EEEEEEEEE EEEEEEE Sbjct: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPT-----------EEEEEEEEEEEEEAEEEEEEE 333 Query: 65 EEEEAPPP 72 + EEAPPP Sbjct: 334 DSEEAPPP 341 Score = 29.3 bits (64), Expect = 2.8 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 4/57 (7%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEE----DEEEEEEEEEEEEEEEEEEEEE 68 E EEEEEEE + + P S + P ++++ DE+ + + +E + EE E Sbjct: 325 EAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAE 381 >gi|58761548 tau tubulin kinase 1 [Homo sapiens] Length = 1321 Score = 56.6 bits (135), Expect = 2e-08 Identities = 31/51 (60%), Positives = 34/51 (66%), Gaps = 14/51 (27%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 EEEEEEE +++EEDEEEEEEEEEEEEEEEEEEEEE Sbjct: 733 EEEEEEE--------------EDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769 Score = 52.4 bits (124), Expect = 3e-07 Identities = 24/41 (58%), Positives = 31/41 (75%) Query: 39 SGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79 +G +++EE+EE+EEEEEE+EEEEEEEEEEE EE Sbjct: 730 NGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770 Score = 51.2 bits (121), Expect = 7e-07 Identities = 22/37 (59%), Positives = 30/37 (81%) Query: 32 PSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 P ++ +++E++EEEEE+EEEEEEEEEEEEEEE Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEE 763 Score = 50.4 bits (119), Expect = 1e-06 Identities = 26/49 (53%), Positives = 32/49 (65%) Query: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVL 90 +++EE+E+EEEEEE+EEEEEEEEEEEE EE A VL Sbjct: 734 EEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVL 782 Score = 45.8 bits (107), Expect = 3e-05 Identities = 22/39 (56%), Positives = 27/39 (69%) Query: 41 PDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79 P + ++EEEEEEE+EEEEEE+EEEEEE EE Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE 765 Score = 40.8 bits (94), Expect = 0.001 Identities = 20/39 (51%), Positives = 25/39 (64%) Query: 41 PDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79 P + + +EEEEEEEE+EEEEEE+EEE EE Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEE 762 Score = 40.4 bits (93), Expect = 0.001 Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 4/42 (9%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEE 59 EEEEEEE +++EE+EEEEEEEEEEEE Sbjct: 734 EEEEEEEDEEEEEEDEEEEE----EEEEEEEEEEEEEEEEEE 771 Score = 39.3 bits (90), Expect = 0.003 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE 57 +EEEEEE +++EE+EEEEEEEEEE Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 39.3 bits (90), Expect = 0.003 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 19 EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEE 58 +EEEEE +++EE+EEEEEEEEEEE Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 34.7 bits (78), Expect = 0.068 Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEE 54 E EEEEEE+ +++EE+EEEEEEE Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 33.5 bits (75), Expect = 0.15 Identities = 17/50 (34%), Positives = 24/50 (48%) Query: 4 LLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEE 53 L P + + E EEEEE+E +++EE+EEEEEE Sbjct: 722 LAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 29.3 bits (64), Expect = 2.8 Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 2/70 (2%) Query: 22 EEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP--PPRVVSEE 79 ++E P + S SG D+E +E EE EE E P + ++EE Sbjct: 547 DKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEE 606 Query: 80 HLRRYAPDPV 89 L+ P P+ Sbjct: 607 DLQHLPPQPL 616 Score = 28.1 bits (61), Expect = 6.3 Identities = 14/44 (31%), Positives = 20/44 (45%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEE 59 E EEEEEEE +++ + V GP E E + +E Sbjct: 759 EEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQE 802 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 56.6 bits (135), Expect = 2e-08 Identities = 33/65 (50%), Positives = 39/65 (60%), Gaps = 20/65 (30%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE---APPPPR 74 EEEEEEE D++EE+EEEEEEE+EEEEEEEEEEEEE PPR Sbjct: 1070 EEEEEEE-----------------DEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR 1112 Query: 75 VVSEE 79 + + Sbjct: 1113 LTKPQ 1117 Score = 55.1 bits (131), Expect = 5e-08 Identities = 28/58 (48%), Positives = 35/58 (60%) Query: 35 SSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVR 92 S S +++EEDEEEEEEEEEEEE+EEEEEEEE + R P V ++ Sbjct: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIK 1122 Score = 53.5 bits (127), Expect = 1e-07 Identities = 28/51 (54%), Positives = 33/51 (64%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +EE E + SP++S DD + EEEEEEEEEEEEEEEEEE EE Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEE 1371 Score = 50.4 bits (119), Expect = 1e-06 Identities = 24/47 (51%), Positives = 30/47 (63%) Query: 22 EEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 E T S +++EE+E+EEEEEEEEEEEE+EEEEEE Sbjct: 1050 ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEE 1096 Score = 42.4 bits (98), Expect = 3e-04 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%) Query: 3 ILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE----E 58 ++ P E + E EEEEEEE + G E++E E E+E+ + Sbjct: 1347 LIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLD 1406 Query: 59 EEEEEEEEEEAP 70 + EEEEEE+E P Sbjct: 1407 DHEEEEEEDEEP 1418 Score = 41.2 bits (95), Expect = 7e-04 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 17/79 (21%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDD-----------------EEDEEEEEEEEEEEEE 60 E+EE+E +T ++S S + V + E +E EEEEEEE+E Sbjct: 1019 EKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDE 1078 Query: 61 EEEEEEEEAPPPPRVVSEE 79 EEEEEEEE EE Sbjct: 1079 EEEEEEEEEEEDEEEEEEE 1097 Score = 39.7 bits (91), Expect = 0.002 Identities = 20/52 (38%), Positives = 25/52 (48%) Query: 6 PNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE 57 P E + EL +E EE +D+EE+EEEEEEEEEE Sbjct: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104 Score = 29.6 bits (65), Expect = 2.2 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 7/54 (12%) Query: 14 ISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEE 67 + + EEEEEE+ S + + DDE+D E E E+EE E +E Sbjct: 1405 LDDHEEEEEEDEEPSHNEDHDA-------DDEDDSHMESAEVEKEELPRESFKE 1451 Score = 28.1 bits (61), Expect = 6.3 Identities = 21/89 (23%), Positives = 38/89 (42%), Gaps = 21/89 (23%) Query: 1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPS---------SSSSVSGPDDDEEDEE-- 49 +++ P + ++ EE++E + +SPS + P ++ EE Sbjct: 1271 LNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETC 1330 Query: 50 ----------EEEEEEEEEEEEEEEEEEE 68 E+ E++ + EEEEEEEEE Sbjct: 1331 APVSPNTSPGEKPEDDLIKPEEEEEEEEE 1359 >gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] Length = 587 Score = 56.6 bits (135), Expect = 2e-08 Identities = 33/63 (52%), Positives = 42/63 (66%), Gaps = 15/63 (23%) Query: 7 NMAE-FDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEE 65 NMA+ ++S+ E+EEEEE G +++EE EEEEEE+EEEEEEEEEEE Sbjct: 349 NMAKVLASLSDDEDEEEEE--------------EGEEEEEEAEEEEEEDEEEEEEEEEEE 394 Query: 66 EEE 68 EEE Sbjct: 395 EEE 397 Score = 52.8 bits (125), Expect = 2e-07 Identities = 27/57 (47%), Positives = 38/57 (66%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +T+ E E+ +E + +S+S +D+EE+EE EEEEEE EEEEEE+EEEE Sbjct: 331 NTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEE 387 Score = 35.8 bits (81), Expect = 0.030 Identities = 18/40 (45%), Positives = 22/40 (55%) Query: 49 EEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDP 88 ++E+EEEEEE EEEEEE EE EE +P Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEP 398 Score = 33.9 bits (76), Expect = 0.12 Identities = 19/46 (41%), Positives = 23/46 (50%) Query: 50 EEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95 ++E+EEEEEE EEEEEE E EE + RG G Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQG 404 >gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] Length = 1083 Score = 55.8 bits (133), Expect = 3e-08 Identities = 27/66 (40%), Positives = 38/66 (57%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +E SE E+ E + S +G + +EE E+EEEEEEEEE +EEEEEE++ Sbjct: 4 SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63 Query: 69 APPPPR 74 PP + Sbjct: 64 DRPPKK 69 Score = 50.4 bits (119), Expect = 1e-06 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66 M++ + + EEE+ E ++ + S ++E+E E+EEEEEEEEE +EEEEE Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 67 EEAPPPPR 74 E+ PP+ Sbjct: 61 EDDDRPPK 68 Score = 48.1 bits (113), Expect = 6e-06 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 7 NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66 N +E + + EE E S + S P+D+EE EEEEEE +EEEEEE++ Sbjct: 8 NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63 Query: 67 EEAPPPPR 74 + P PR Sbjct: 64 DRPPKKPR 71 Score = 33.1 bits (74), Expect = 0.20 Identities = 21/64 (32%), Positives = 31/64 (48%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75 E EE +EEE P G DE D ++E E+E++ E+ E+ E+A V Sbjct: 50 EEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNV 109 Query: 76 VSEE 79 V +E Sbjct: 110 VLDE 113 >gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 55.8 bits (133), Expect = 3e-08 Identities = 27/66 (40%), Positives = 38/66 (57%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +E SE E+ E + S +G + +EE E+EEEEEEEEE +EEEEEE++ Sbjct: 4 SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63 Query: 69 APPPPR 74 PP + Sbjct: 64 DRPPKK 69 Score = 50.4 bits (119), Expect = 1e-06 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66 M++ + + EEE+ E ++ + S ++E+E E+EEEEEEEEE +EEEEE Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 67 EEAPPPPR 74 E+ PP+ Sbjct: 61 EDDDRPPK 68 Score = 48.1 bits (113), Expect = 6e-06 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 7 NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66 N +E + + EE E S + S P+D+EE EEEEEE +EEEEEE++ Sbjct: 8 NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63 Query: 67 EEAPPPPR 74 + P PR Sbjct: 64 DRPPKKPR 71 Score = 34.7 bits (78), Expect = 0.068 Identities = 20/62 (32%), Positives = 32/62 (51%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVS 77 EEEEEE+ P + D +++ E+E++ E+ E+ E+EE EA VV Sbjct: 56 EEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVL 115 Query: 78 EE 79 +E Sbjct: 116 DE 117 >gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 55.8 bits (133), Expect = 3e-08 Identities = 27/66 (40%), Positives = 38/66 (57%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +E SE E+ E + S +G + +EE E+EEEEEEEEE +EEEEEE++ Sbjct: 4 SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63 Query: 69 APPPPR 74 PP + Sbjct: 64 DRPPKK 69 Score = 50.4 bits (119), Expect = 1e-06 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66 M++ + + EEE+ E ++ + S ++E+E E+EEEEEEEEE +EEEEE Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 67 EEAPPPPR 74 E+ PP+ Sbjct: 61 EDDDRPPK 68 Score = 48.1 bits (113), Expect = 6e-06 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 7 NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66 N +E + + EE E S + S P+D+EE EEEEEE +EEEEEE++ Sbjct: 8 NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63 Query: 67 EEAPPPPR 74 + P PR Sbjct: 64 DRPPKKPR 71 Score = 34.7 bits (78), Expect = 0.068 Identities = 20/62 (32%), Positives = 32/62 (51%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVS 77 EEEEEE+ P + D +++ E+E++ E+ E+ E+EE EA VV Sbjct: 56 EEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVL 115 Query: 78 EE 79 +E Sbjct: 116 DE 117 >gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 55.8 bits (133), Expect = 3e-08 Identities = 27/66 (40%), Positives = 38/66 (57%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +E SE E+ E + S +G + +EE E+EEEEEEEEE +EEEEEE++ Sbjct: 4 SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63 Query: 69 APPPPR 74 PP + Sbjct: 64 DRPPKK 69 Score = 50.4 bits (119), Expect = 1e-06 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Query: 8 MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66 M++ + + EEE+ E ++ + S ++E+E E+EEEEEEEEE +EEEEE Sbjct: 1 MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60 Query: 67 EEAPPPPR 74 E+ PP+ Sbjct: 61 EDDDRPPK 68 Score = 48.1 bits (113), Expect = 6e-06 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 7 NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66 N +E + + EE E S + S P+D+EE EEEEEE +EEEEEE++ Sbjct: 8 NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63 Query: 67 EEAPPPPR 74 + P PR Sbjct: 64 DRPPKKPR 71 Score = 34.7 bits (78), Expect = 0.068 Identities = 20/62 (32%), Positives = 32/62 (51%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVS 77 EEEEEE+ P + D +++ E+E++ E+ E+ E+EE EA VV Sbjct: 56 EEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVL 115 Query: 78 EE 79 +E Sbjct: 116 DE 117 >gi|118600967 shroom family member 4 [Homo sapiens] Length = 1493 Score = 54.7 bits (130), Expect = 6e-08 Identities = 26/36 (72%), Positives = 29/36 (80%) Query: 44 DEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79 +EE+EEEEEEEEEEEEEEEE EEEE PP+ S E Sbjct: 1132 EEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSE 1167 Score = 54.7 bits (130), Expect = 6e-08 Identities = 24/30 (80%), Positives = 28/30 (93%) Query: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71 +++EE+EEEEEEEEEEEEEE EEEEEE PP Sbjct: 1132 EEEEEEEEEEEEEEEEEEEEAEEEEEELPP 1161 Score = 53.9 bits (128), Expect = 1e-07 Identities = 26/36 (72%), Positives = 29/36 (80%) Query: 43 DDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSE 78 ++EE+EEEEEEEEEEEEEEE EEEEE PP SE Sbjct: 1132 EEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSE 1167 Score = 40.8 bits (94), Expect = 0.001 Identities = 18/37 (48%), Positives = 26/37 (70%) Query: 45 EEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHL 81 ++ ++++++EEEEEEEEEEEEEEE EE L Sbjct: 1123 QQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL 1159 Score = 37.0 bits (84), Expect = 0.014 Identities = 15/42 (35%), Positives = 27/42 (64%) Query: 45 EEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP 86 ++ +++++++++EEEEEEEEEEEE +EE P Sbjct: 1120 QQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPP 1161 Score = 36.2 bits (82), Expect = 0.023 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 17/71 (23%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75 E EEEEEEE +++EE+EEEEE EEEEEE + E + Sbjct: 1132 EEEEEEEEE-----------------EEEEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174 Query: 76 VSEEHLRRYAP 86 EE L + P Sbjct: 1175 NPEEVLEQPQP 1185 Score = 33.5 bits (75), Expect = 0.15 Identities = 13/52 (25%), Positives = 26/52 (50%) Query: 6 PNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE 57 PN ++ +++++++ +++EE+EEE EEEEEE Sbjct: 1107 PNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158 >gi|4503257 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 53.9 bits (128), Expect = 1e-07 Identities = 26/54 (48%), Positives = 34/54 (62%) Query: 15 SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 + L+ E S PS+S + + +DDEE +EEEEEEEEEEEEE + EEE Sbjct: 411 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 464 Score = 44.7 bits (104), Expect = 7e-05 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDD---DEEDEEEEEEEEEEEEEEEEEE 65 A S + E + S PS +S P + +DE++EE +EEEEEEEEEEE Sbjct: 396 ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEE 455 Query: 66 EE 67 EE Sbjct: 456 EE 457 Score = 42.7 bits (99), Expect = 2e-04 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 16/90 (17%) Query: 10 EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE----EE 65 E D E EEEEEEE AT S ++D E +E +E++EEE+EEEE ++ Sbjct: 442 ESDEEEEEEEEEEEEEATDSEE----------EEDLEQMQEGQEDDEEEDEEEEAAAGKD 491 Query: 66 EEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95 +++P +S E + P + R +G Sbjct: 492 GDKSPMSSLQISNE--KNLEPGKQISRSSG 519 Score = 40.0 bits (92), Expect = 0.002 Identities = 22/60 (36%), Positives = 30/60 (50%) Query: 24 EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRR 83 EA+ S S + G E ++E++EE +EEEEEEEEEE EE L + Sbjct: 410 EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 469 Score = 28.1 bits (61), Expect = 6.3 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 9/79 (11%) Query: 5 LPNMAEFDTISELEEEEEEEAA--TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62 L M E E E+EEEE AA SP SS +S +E+ E ++ Sbjct: 467 LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS-------NEKNLEPGKQISRSSG 519 Query: 63 EEEEEEAPPPPRVVSEEHL 81 E++ + P ++SEE L Sbjct: 520 EQQNKGRIVSPSLLSEEPL 538 >gi|215422388 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 53.9 bits (128), Expect = 1e-07 Identities = 26/54 (48%), Positives = 34/54 (62%) Query: 15 SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 + L+ E S PS+S + + +DDEE +EEEEEEEEEEEEE + EEE Sbjct: 411 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 464 Score = 44.7 bits (104), Expect = 7e-05 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDD---DEEDEEEEEEEEEEEEEEEEEE 65 A S + E + S PS +S P + +DE++EE +EEEEEEEEEEE Sbjct: 396 ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEE 455 Query: 66 EE 67 EE Sbjct: 456 EE 457 Score = 42.7 bits (99), Expect = 2e-04 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 16/90 (17%) Query: 10 EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE----EE 65 E D E EEEEEEE AT S ++D E +E +E++EEE+EEEE ++ Sbjct: 442 ESDEEEEEEEEEEEEEATDSEE----------EEDLEQMQEGQEDDEEEDEEEEAAAGKD 491 Query: 66 EEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95 +++P +S E + P + R +G Sbjct: 492 GDKSPMSSLQISNE--KNLEPGKQISRSSG 519 Score = 40.0 bits (92), Expect = 0.002 Identities = 22/60 (36%), Positives = 30/60 (50%) Query: 24 EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRR 83 EA+ S S + G E ++E++EE +EEEEEEEEEE EE L + Sbjct: 410 EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 469 Score = 28.1 bits (61), Expect = 6.3 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 9/79 (11%) Query: 5 LPNMAEFDTISELEEEEEEEAA--TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62 L M E E E+EEEE AA SP SS +S +E+ E ++ Sbjct: 467 LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS-------NEKNLEPGKQISRSSG 519 Query: 63 EEEEEEAPPPPRVVSEEHL 81 E++ + P ++SEE L Sbjct: 520 EQQNKGRIVSPSLLSEEPL 538 >gi|215422366 death-domain associated protein isoform b [Homo sapiens] Length = 752 Score = 53.9 bits (128), Expect = 1e-07 Identities = 26/54 (48%), Positives = 34/54 (62%) Query: 15 SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 + L+ E S PS+S + + +DDEE +EEEEEEEEEEEEE + EEE Sbjct: 423 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 476 Score = 44.7 bits (104), Expect = 7e-05 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDD---DEEDEEEEEEEEEEEEEEEEEE 65 A S + E + S PS +S P + +DE++EE +EEEEEEEEEEE Sbjct: 408 ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEE 467 Query: 66 EE 67 EE Sbjct: 468 EE 469 Score = 42.7 bits (99), Expect = 2e-04 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 16/90 (17%) Query: 10 EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE----EE 65 E D E EEEEEEE AT S ++D E +E +E++EEE+EEEE ++ Sbjct: 454 ESDEEEEEEEEEEEEEATDSEE----------EEDLEQMQEGQEDDEEEDEEEEAAAGKD 503 Query: 66 EEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95 +++P +S E + P + R +G Sbjct: 504 GDKSPMSSLQISNE--KNLEPGKQISRSSG 531 Score = 40.0 bits (92), Expect = 0.002 Identities = 22/60 (36%), Positives = 30/60 (50%) Query: 24 EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRR 83 EA+ S S + G E ++E++EE +EEEEEEEEEE EE L + Sbjct: 422 EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 481 Score = 28.1 bits (61), Expect = 6.3 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 9/79 (11%) Query: 5 LPNMAEFDTISELEEEEEEEAA--TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62 L M E E E+EEEE AA SP SS +S +E+ E ++ Sbjct: 479 LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS-------NEKNLEPGKQISRSSG 531 Query: 63 EEEEEEAPPPPRVVSEEHL 81 E++ + P ++SEE L Sbjct: 532 EQQNKGRIVSPSLLSEEPL 550 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 53.9 bits (128), Expect = 1e-07 Identities = 25/64 (39%), Positives = 41/64 (64%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + +++++ SSS + S +++EE++EEEEEEEEEEEEEEE+E ++ Sbjct: 1372 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431 Query: 69 APPP 72 + P Sbjct: 1432 SKSP 1435 Score = 49.7 bits (117), Expect = 2e-06 Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 5/64 (7%) Query: 15 SELEE-----EEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69 +ELEE +++++ SSS ++EE+E+EEEEEEEEEEEEEEE+E + Sbjct: 1372 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431 Query: 70 PPPP 73 P Sbjct: 1432 SKSP 1435 Score = 40.4 bits (93), Expect = 0.001 Identities = 20/51 (39%), Positives = 27/51 (52%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 ++ E EE S + +D + + EEEEEE+EEEEEEEEE Sbjct: 1370 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420 Score = 40.0 bits (92), Expect = 0.002 Identities = 17/60 (28%), Positives = 36/60 (60%) Query: 23 EEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLR 82 +E ++S + +S +++EE+EEEEEEEEE+E ++ + + +++ ++ LR Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLR 1452 Score = 28.9 bits (63), Expect = 3.7 Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 12/79 (15%) Query: 13 TISELEEEEEEEAATSSSSPSSSSSVSG-------PDDDEEDEEEEEEEEEEEEEEEEEE 65 T+S+ E EE++ + P V G +D E+ + +E EE E E+E+ Sbjct: 1308 TVSDGESGEEKK-----TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1362 Query: 66 EEEAPPPPRVVSEEHLRRY 84 + EE+ R Y Sbjct: 1363 RPRTRSAKKAELEENQRSY 1381 Score = 28.9 bits (63), Expect = 3.7 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSG--------PDDDEEDEEEEEEEEEEEEEEEEEEEE 67 E EEEEEEE + S S G DD E + +EEEE + E E Sbjct: 1414 EEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERE 1473 Query: 68 EAPPPPRVVSE 78 R V E Sbjct: 1474 REREKLREVIE 1484 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 53.9 bits (128), Expect = 1e-07 Identities = 25/64 (39%), Positives = 41/64 (64%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + +++++ SSS + S +++EE++EEEEEEEEEEEEEEE+E ++ Sbjct: 1410 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469 Query: 69 APPP 72 + P Sbjct: 1470 SKSP 1473 Score = 49.7 bits (117), Expect = 2e-06 Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 5/64 (7%) Query: 15 SELEE-----EEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69 +ELEE +++++ SSS ++EE+E+EEEEEEEEEEEEEEE+E + Sbjct: 1410 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469 Query: 70 PPPP 73 P Sbjct: 1470 SKSP 1473 Score = 40.4 bits (93), Expect = 0.001 Identities = 20/51 (39%), Positives = 27/51 (52%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 ++ E EE S + +D + + EEEEEE+EEEEEEEEE Sbjct: 1408 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1458 Score = 40.0 bits (92), Expect = 0.002 Identities = 17/60 (28%), Positives = 36/60 (60%) Query: 23 EEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLR 82 +E ++S + +S +++EE+EEEEEEEEE+E ++ + + +++ ++ LR Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLR 1490 Score = 28.9 bits (63), Expect = 3.7 Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 12/79 (15%) Query: 13 TISELEEEEEEEAATSSSSPSSSSSVSG-------PDDDEEDEEEEEEEEEEEEEEEEEE 65 T+S+ E EE++ + P V G +D E+ + +E EE E E+E+ Sbjct: 1346 TVSDGESGEEKK-----TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1400 Query: 66 EEEAPPPPRVVSEEHLRRY 84 + EE+ R Y Sbjct: 1401 RPRTRSAKKAELEENQRSY 1419 Score = 28.9 bits (63), Expect = 3.7 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 8/71 (11%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSG--------PDDDEEDEEEEEEEEEEEEEEEEEEEE 67 E EEEEEEE + S S G DD E + +EEEE + E E Sbjct: 1452 EEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERE 1511 Query: 68 EAPPPPRVVSE 78 R V E Sbjct: 1512 REREKLREVIE 1522 Score = 28.1 bits (61), Expect = 6.3 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 18/85 (21%) Query: 17 LEEEEEEEAATSSSSPSSSSSVSG-----------PDDDEEDEEEEEEEEEEEEEEEEEE 65 +E +EE ++S S SS SS S DD++ ++E E+ E E + Sbjct: 57 MENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDI 116 Query: 66 EEEAPPPPRVVSEEHLRRYAPDPVL 90 ++ P V+ + P+PVL Sbjct: 117 TMQSLPKGTVIVQ-------PEPVL 134 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 53.9 bits (128), Expect = 1e-07 Identities = 26/51 (50%), Positives = 31/51 (60%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 +E+EE+E D+D ED E+EEEEEEEEEEEEEEEE E Sbjct: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169 Score = 50.4 bits (119), Expect = 1e-06 Identities = 30/70 (42%), Positives = 36/70 (51%), Gaps = 13/70 (18%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEE-------------EEEEE 58 + + E EE+E EE + + P D EE+EE EEE EEEEE Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156 Query: 59 EEEEEEEEEE 68 EEEEEEEEEE Sbjct: 157 EEEEEEEEEE 166 Score = 47.0 bits (110), Expect = 1e-05 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 9/78 (11%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEE---------EEEE 62 D +++E+EE+E S D++ + EEEEE EEE+E E+EE Sbjct: 94 DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153 Query: 63 EEEEEEAPPPPRVVSEEH 80 EEEEEE +E+H Sbjct: 154 EEEEEEEEEEEEEENEDH 171 Score = 46.6 bits (109), Expect = 2e-05 Identities = 22/51 (43%), Positives = 29/51 (56%) Query: 16 ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66 E +EE + E G D ++E+EEEEEEEEEEEEEE E+ + Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 Score = 43.1 bits (100), Expect = 2e-04 Identities = 21/52 (40%), Positives = 27/52 (51%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE 63 D E + EEEE D++EE+EEEEEEEEEEE E+ + Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 Score = 38.1 bits (87), Expect = 0.006 Identities = 19/51 (37%), Positives = 26/51 (50%) Query: 10 EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60 E D + EEEEE E +++EE+EEEEEEEE E+ + Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 Score = 35.4 bits (80), Expect = 0.040 Identities = 19/51 (37%), Positives = 26/51 (50%) Query: 29 SSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79 SSS G +D +E EE+E EE E+ +E +E+EE R EE Sbjct: 84 SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEE 134 Score = 35.0 bits (79), Expect = 0.052 Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 10/53 (18%) Query: 26 ATSSSSPSSSSSVSGPDDDEEDEEEEEE----------EEEEEEEEEEEEEEE 68 A SSS S D DE++E+E EE E+EE+EE + EEEEE Sbjct: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEE 134 Score = 31.2 bits (69), Expect = 0.75 Identities = 15/53 (28%), Positives = 28/53 (52%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAP 70 +++ +E A + S S + D+ D E+ +E+EE+E EE E+ + P Sbjct: 65 DKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117 Score = 29.3 bits (64), Expect = 2.8 Identities = 13/54 (24%), Positives = 29/54 (53%) Query: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71 ++++ +E A + + S D+ ++ + E+ +E+EE+E EE E+ P Sbjct: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117 Score = 28.9 bits (63), Expect = 3.7 Identities = 13/54 (24%), Positives = 28/54 (51%) Query: 19 EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPP 72 ++++ + P + + S D+ +D + E+ +E+EE+E EE E+ P Sbjct: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117 >gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] Length = 285 Score = 53.5 bits (127), Expect = 1e-07 Identities = 25/63 (39%), Positives = 35/63 (55%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71 + + E EEEE+EEAA ++ + EE EE+EEEEE +E E+ EE+ P Sbjct: 6 EVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 65 Query: 72 PPR 74 PR Sbjct: 66 KPR 68 Score = 31.6 bits (70), Expect = 0.57 Identities = 17/38 (44%), Positives = 21/38 (55%) Query: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79 D +E EE EEEE+EE EE+EE E +EE Sbjct: 3 DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEE 40 Score = 31.2 bits (69), Expect = 0.75 Identities = 18/44 (40%), Positives = 22/44 (50%) Query: 44 DEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPD 87 D E+ EE EEEE+EE EE+EE A +E R D Sbjct: 3 DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEED 46 >gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] Length = 288 Score = 53.5 bits (127), Expect = 1e-07 Identities = 25/63 (39%), Positives = 35/63 (55%) Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71 + + E EEEE+EEAA ++ + EE EE+EEEEE +E E+ EE+ P Sbjct: 6 EVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 65 Query: 72 PPR 74 PR Sbjct: 66 KPR 68 Score = 31.6 bits (70), Expect = 0.57 Identities = 17/38 (44%), Positives = 21/38 (55%) Query: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79 D +E EE EEEE+EE EE+EE E +EE Sbjct: 3 DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEE 40 Score = 31.2 bits (69), Expect = 0.75 Identities = 18/44 (40%), Positives = 22/44 (50%) Query: 44 DEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPD 87 D E+ EE EEEE+EE EE+EE A +E R D Sbjct: 3 DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEED 46 >gi|28274705 family with sequence similarity 9, member A [Homo sapiens] Length = 332 Score = 53.5 bits (127), Expect = 1e-07 Identities = 29/68 (42%), Positives = 43/68 (63%) Query: 1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60 +++L +AE E EE E AA +++ + +++ + EDEEEEE+EEEEE+E Sbjct: 175 LNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKE 234 Query: 61 EEEEEEEE 68 EEEEE EE Sbjct: 235 EEEEEGEE 242 Score = 50.1 bits (118), Expect = 2e-06 Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 3 ILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62 I++ + E + E E+EEEEE G + EE EEEEEEEEEEEEEE+ Sbjct: 217 IVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276 Query: 63 ---EEEEEEAPPPPRVVSEEHLRRYAP 86 +E+++ P V LR P Sbjct: 277 IKAFQEKQKRWQQPTGVRSWRLREMKP 303 Score = 47.8 bits (112), Expect = 8e-06 Identities = 26/60 (43%), Positives = 31/60 (51%) Query: 9 AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68 AE + + EEEE+EE G ++ EE E EE EEEEEEEEEEEE Sbjct: 214 AEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273 Score = 45.4 bits (106), Expect = 4e-05 Identities = 24/65 (36%), Positives = 42/65 (64%) Query: 4 LLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE 63 LL + E+ + ++E EE A ++++ +++++ + E E+EEEEE+EEEEE+ Sbjct: 174 LLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEK 233 Query: 64 EEEEE 68 EEEEE Sbjct: 234 EEEEE 238 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.132 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,399,874 Number of Sequences: 37866 Number of extensions: 728160 Number of successful extensions: 68639 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1704 Number of HSP's successfully gapped in prelim test: 288 Number of HSP's that attempted gapping in prelim test: 14664 Number of HSP's gapped (non-prelim): 23313 length of query: 224 length of database: 18,247,518 effective HSP length: 98 effective length of query: 126 effective length of database: 14,536,650 effective search space: 1831617900 effective search space used: 1831617900 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.