Guide to the Human Genome
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Search of human proteins with 154759293

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]        464   e-131
gi|6912276 cysteine-rich hydrophobic domain 2 [Homo sapiens]          285   2e-77
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     68   6e-12
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     68   6e-12
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    68   6e-12
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    68   6e-12
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    68   6e-12
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    68   6e-12
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    68   6e-12
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    68   6e-12
gi|17975763 myelin transcription factor 1 [Homo sapiens]               63   2e-10
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    59   3e-09
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    57   2e-08
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        57   2e-08
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    57   2e-08
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              57   2e-08
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       56   3e-08
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       56   3e-08
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       56   3e-08
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        56   3e-08
gi|118600967 shroom family member 4 [Homo sapiens]                     55   6e-08
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    54   1e-07
gi|215422388 death-domain associated protein isoform a [Homo sap...    54   1e-07
gi|215422366 death-domain associated protein isoform b [Homo sap...    54   1e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    54   1e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    54   1e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          54   1e-07
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]        54   1e-07
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]        54   1e-07
gi|28274705 family with sequence similarity 9, member A [Homo sa...    54   1e-07

>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
          Length = 224

 Score =  464 bits (1193), Expect = e-131
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60
           MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
Sbjct: 1   MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60

Query: 61  EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP 120
           EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
Sbjct: 61  EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP 120

Query: 121 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW 180
           EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
Sbjct: 121 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW 180

Query: 181 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD 224
           ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
Sbjct: 181 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD 224


>gi|6912276 cysteine-rich hydrophobic domain 2 [Homo sapiens]
          Length = 165

 Score =  285 bits (729), Expect = 2e-77
 Identities = 131/168 (77%), Positives = 149/168 (88%), Gaps = 7/168 (4%)

Query: 57  EEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTG 116
           +E  EEEE+EE A        EE L +Y+PDPV+VRG+GH+TVFGLSNKF++EFPS LTG
Sbjct: 5   DEIYEEEEDEERA-------LEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTG 57

Query: 117 KVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQK 176
           KVAPEEFK SI RVN+CLKK LPVNV+WLLCGCLCCCCTLGCS+WPVICL+KRTRRSI+K
Sbjct: 58  KVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEK 117

Query: 177 LIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD 224
           L+EWENNRLYHKL LHW+L+KRKCET+NMMEYVILIEFLPK PIFRPD
Sbjct: 118 LLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD 165


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8   MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
           M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 245 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 304

Query: 62  EEEEEEEAPPPPRVVSEE 79
           EEEEEEE        SE+
Sbjct: 305 EEEEEEETGSNSEEASEQ 322



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 272 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 319

Query: 69  APPPPRVVSEEHL 81
           +      VSEE +
Sbjct: 320 SEQSAEEVSEEEM 332



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 302 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 361

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 362 AEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLP---ALQGCRSVEEFQCLNR 418

Query: 106 FD 107
            +
Sbjct: 419 IE 420


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8   MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
           M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314

Query: 62  EEEEEEEAPPPPRVVSEE 79
           EEEEEEE        SE+
Sbjct: 315 EEEEEEETGSNSEEASEQ 332



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 282 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 329

Query: 69  APPPPRVVSEEHL 81
           +      VSEE +
Sbjct: 330 SEQSAEEVSEEEM 342



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 312 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 371

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 372 AEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLP---ALQGCRSVEEFQCLNR 428

Query: 106 FD 107
            +
Sbjct: 429 IE 430


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8   MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
           M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 246 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 305

Query: 62  EEEEEEEAPPPPRVVSEE 79
           EEEEEEE        SE+
Sbjct: 306 EEEEEEETGSNSEEASEQ 323



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 273 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 320

Query: 69  APPPPRVVSEEHL 81
           +      VSEE +
Sbjct: 321 SEQSAEEVSEEEM 333



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 303 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 362

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 363 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 419

Query: 106 FD 107
            +
Sbjct: 420 IE 421



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 10/82 (12%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEE-----EEEEEEEEEEEEEEEE 66
           D++ +  EE++  A       S    V    D++  E++     E+E E E  +   EE+
Sbjct: 71  DSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ 130

Query: 67  EEAP-----PPPRVVSEEHLRR 83
           ++A         R ++ EH RR
Sbjct: 131 DKARREWERQKRREMAREHSRR 152


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8   MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
           M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314

Query: 62  EEEEEEEAPPPPRVVSEE 79
           EEEEEEE        SE+
Sbjct: 315 EEEEEEETGSNSEEASEQ 332



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 282 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 329

Query: 69  APPPPRVVSEEHL 81
           +      VSEE +
Sbjct: 330 SEQSAEEVSEEEM 342



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 312 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 371

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 372 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 428

Query: 106 FD 107
            +
Sbjct: 429 IE 430



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 10/82 (12%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEE-----EEEEEEEEEEEEEEEE 66
           D++ +  EE++  A       S    V    D++  E++     E+E E E  +   EE+
Sbjct: 71  DSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ 130

Query: 67  EEAP-----PPPRVVSEEHLRR 83
           ++A         R ++ EH RR
Sbjct: 131 DKARREWERQKRREMAREHSRR 152


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8   MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
           M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 223 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 282

Query: 62  EEEEEEEAPPPPRVVSEE 79
           EEEEEEE        SE+
Sbjct: 283 EEEEEEETGSNSEEASEQ 300



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 250 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 297

Query: 69  APPPPRVVSEEHL 81
           +      VSEE +
Sbjct: 298 SEQSAEEVSEEEM 310



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 280 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 339

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 340 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 396

Query: 106 FD 107
            +
Sbjct: 397 IE 398


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8   MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
           M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 212 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 271

Query: 62  EEEEEEEAPPPPRVVSEE 79
           EEEEEEE        SE+
Sbjct: 272 EEEEEEETGSNSEEASEQ 289



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 239 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 286

Query: 69  APPPPRVVSEEHL 81
           +      VSEE +
Sbjct: 287 SEQSAEEVSEEEM 299



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 269 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 328

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 329 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 385

Query: 106 FD 107
            +
Sbjct: 386 IE 387



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 10/82 (12%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEE-----EEEEEEEEEEEEEEEE 66
           D++ +  EE++  A       S    V    D++  E++     E+E E E  +   EE+
Sbjct: 37  DSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ 96

Query: 67  EEAP-----PPPRVVSEEHLRR 83
           ++A         R ++ EH RR
Sbjct: 97  DKARREWERQKRREMAREHSRR 118


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins)
          isoform 3 [Homo sapiens]
          Length = 526

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8  MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
          M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 1  MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60

Query: 62 EEEEEEEAPPPPRVVSEE 79
          EEEEEEE        SE+
Sbjct: 61 EEEEEEETGSNSEEASEQ 78



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9  AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
          AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 28 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 75

Query: 69 APPPPRVVSEEHL 81
          +      VSEE +
Sbjct: 76 SEQSAEEVSEEEM 88



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 58  EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 117

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 118 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 174

Query: 106 FD 107
            +
Sbjct: 175 IE 176


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/78 (48%), Positives = 50/78 (64%), Gaps = 6/78 (7%)

Query: 8   MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEE------EEEEEEEEE 61
           M E D +S+L++  + E  TSS+  SS+ S SG +++EE+EEEEE      EE EEEEEE
Sbjct: 257 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 316

Query: 62  EEEEEEEAPPPPRVVSEE 79
           EEEEEEE        SE+
Sbjct: 317 EEEEEEETGSNSEEASEQ 334



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE  + SE EEEEEEE     S+             EE EEEEEEEEEEEEE     EE 
Sbjct: 284 AESGSGSEEEEEEEEEEEEEGST------------SEESEEEEEEEEEEEEETGSNSEEA 331

Query: 69  APPPPRVVSEEHL 81
           +      VSEE +
Sbjct: 332 SEQSAEEVSEEEM 344



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 33/122 (27%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------------------- 55
           E EEEEEEE   S+S  +S  S     ++E  E+EE E E                    
Sbjct: 314 EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 373

Query: 56  -EEEEEE---------EEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNK 105
            EEE  E         E +   ++P    +  ++ L +Y P    ++G   +  F   N+
Sbjct: 374 AEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP---ALQGCRSVEEFQCLNR 430

Query: 106 FD 107
            +
Sbjct: 431 IE 432


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 33/80 (41%), Positives = 42/80 (52%)

Query: 17  LEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVV 76
           LE+   EE++      S        +++EE+EEE+EEEEEEEEEEEEEEEEE        
Sbjct: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299

Query: 77  SEEHLRRYAPDPVLVRGAGH 96
            EE     APD +      H
Sbjct: 300 EEEEEEEAAPDVIFQEDTSH 319



 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 35/80 (43%), Positives = 44/80 (55%), Gaps = 4/80 (5%)

Query: 14  ISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPP 73
           +S  EE+EEEE                 +++EE+EEEEEEEEEEEEEEEEEEEEE   P 
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEE----EEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310

Query: 74  RVVSEEHLRRYAPDPVLVRG 93
            +  E+     A     +RG
Sbjct: 311 VIFQEDTSHTSAQKAPELRG 330



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 26/68 (38%), Positives = 35/68 (51%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71
           + + E+  E  ++    S   ++S   S        EEE+EEEEEEEEEEEE+EEEE   
Sbjct: 222 EEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEE 281

Query: 72  PPRVVSEE 79
                 EE
Sbjct: 282 EEEEEEEE 289



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 28/71 (39%), Positives = 34/71 (47%), Gaps = 9/71 (12%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEE---------DEEEEEEEEEEEEEEEEEEEEE 68
           + EE  E  T  S      S+     +E          +EE+EEEEEEEEEEEE+EEEEE
Sbjct: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279

Query: 69  APPPPRVVSEE 79
                    EE
Sbjct: 280 EEEEEEEEEEE 290



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 7/68 (10%)

Query: 10  EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE-------EEEEE 62
           E D   E EEEEEEE                 +++EE+EEEEEEEEEE       +E+  
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318

Query: 63  EEEEEEAP 70
               ++AP
Sbjct: 319 HTSAQKAP 326



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 19/64 (29%), Positives = 28/64 (43%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75
           E EEE+EEE                 +++EE+EEEEEE   +   +E+     A   P +
Sbjct: 269 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328

Query: 76  VSEE 79
              E
Sbjct: 329 RGPE 332



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 15/52 (28%), Positives = 26/52 (50%)

Query: 17  LEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           ++ E+ EE    ++  S        +D   +E  +++     EEE+EEEEEE
Sbjct: 216 IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEE 267



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 15  SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEE 56
           S L EEE EE     S P++ S  S   DD+E  EE  EE +
Sbjct: 738 SRLREEEPEE-----SEPAAHSFASSEADDQEVSEENFEERK 774



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 24/74 (32%)

Query: 16  ELEEEEEEEAA--------TSSSSPSSSSSVSGPD----------------DDEEDEEEE 51
           E EEEEEEEAA        TS +S   +  + GP+                DD++DE+  
Sbjct: 298 EEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTH 357

Query: 52  EEEEEEEEEEEEEE 65
             +    +E E ++
Sbjct: 358 SRKSTVTDESEMQD 371


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 31/66 (46%), Positives = 36/66 (54%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75
           EL  E   EA              G D +EE+EEEEE+EEEEEEEE+EEEEEE       
Sbjct: 832 ELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEK 891

Query: 76  VSEEHL 81
            +EE L
Sbjct: 892 GNEEPL 897



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 24/54 (44%), Positives = 32/54 (59%)

Query: 15  SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           +E +E   E    + +         G D  + +EEEEEEEE+EEEEEEEE+EEE
Sbjct: 828 TESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE 881



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDD----DEEDEEEEEEEEEEEEEEEEEEEEEAPPPP 73
           E E E +  ++ +   + +   G +D    D  D EEEEEEEEE+EEEEEEEE+E     
Sbjct: 825 EGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEE 884

Query: 74  RVVSEE 79
               EE
Sbjct: 885 EEEEEE 890



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 28/59 (47%), Positives = 33/59 (55%), Gaps = 20/59 (33%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAP 70
           D+  E EEEEE+E                    EE+EEEE+EEEEEEEEEEEE+  E P
Sbjct: 858 DSEEEEEEEEEQE--------------------EEEEEEEQEEEEEEEEEEEEKGNEEP 896



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 24/71 (33%), Positives = 34/71 (47%)

Query: 19  EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSE 78
           E E +E +  +   + +      D    D  + EEEEEEEEE+EEEEEEE         E
Sbjct: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEE 886

Query: 79  EHLRRYAPDPV 89
           E   +   +P+
Sbjct: 887 EEEEKGNEEPL 897



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEE-------EEEEEEEEEEEEEEE 68
           E+  E+ E       + S   S     + + DE+  E+       + EEEEEEEEE+EEE
Sbjct: 813 EIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEE 872

Query: 69  APPPPRVVSEE 79
                +   EE
Sbjct: 873 EEEEEQEEEEE 883



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 15  SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69
           SE EEEEEEE                 +++EE+EEE+  EE    +  E  +++A
Sbjct: 859 SEEEEEEEEEQEEEEEEEEQEEE----EEEEEEEEEKGNEEPLSLDWPETRQKQA 909



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 16/51 (31%), Positives = 22/51 (43%)

Query: 19  EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69
           E E EE +   + P            EE E+E E E + + E E+E E  A
Sbjct: 766 EGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHA 816



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 1/59 (1%)

Query: 10  EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           E +T  E E EE+    T        +   G  ++ EDE E E + + E E+E E   E
Sbjct: 760 EGETAGEGETEEKSGGETQPEG-EGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAE 817


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 32/68 (47%), Positives = 39/68 (57%), Gaps = 11/68 (16%)

Query: 5   LPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEE 64
           LP      +  +L E +EE+    SS             +EE+EEEEEEEEE EEEEEEE
Sbjct: 285 LPTDLPAPSAPDLTEPKEEQPPVPSSPT-----------EEEEEEEEEEEEEAEEEEEEE 333

Query: 65  EEEEAPPP 72
           + EEAPPP
Sbjct: 334 DSEEAPPP 341



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 4/57 (7%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEE----DEEEEEEEEEEEEEEEEEEEEE 68
           E EEEEEEE +  +  P S    + P ++++    DE+ +   +  +E   + EE E
Sbjct: 325 EAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAE 381


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 31/51 (60%), Positives = 34/51 (66%), Gaps = 14/51 (27%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           EEEEEEE                 +++EEDEEEEEEEEEEEEEEEEEEEEE
Sbjct: 733 EEEEEEE--------------EDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 24/41 (58%), Positives = 31/41 (75%)

Query: 39  SGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
           +G +++EE+EE+EEEEEE+EEEEEEEEEEE         EE
Sbjct: 730 NGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 22/37 (59%), Positives = 30/37 (81%)

Query: 32  PSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           P ++      +++E++EEEEE+EEEEEEEEEEEEEEE
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEE 763



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 26/49 (53%), Positives = 32/49 (65%)

Query: 42  DDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVL 90
           +++EE+E+EEEEEE+EEEEEEEEEEEE         EE     A   VL
Sbjct: 734 EEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVL 782



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 22/39 (56%), Positives = 27/39 (69%)

Query: 41  PDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
           P  + ++EEEEEEE+EEEEEE+EEEEEE         EE
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE 765



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 20/39 (51%), Positives = 25/39 (64%)

Query: 41  PDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
           P   + + +EEEEEEEE+EEEEEE+EEE         EE
Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEE 762



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 4/42 (9%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEE 59
           EEEEEEE                 +++EE+EEEEEEEEEEEE
Sbjct: 734 EEEEEEEDEEEEEEDEEEEE----EEEEEEEEEEEEEEEEEE 771



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 18/40 (45%), Positives = 23/40 (57%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE 57
           +EEEEEE                 +++EE+EEEEEEEEEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 18/40 (45%), Positives = 23/40 (57%)

Query: 19  EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEE 58
           +EEEEE                 +++EE+EEEEEEEEEEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEE 54
           E EEEEEE+                 +++EE+EEEEEEE
Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 4   LLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEE 53
           L P   + +   E EEEEE+E                 +++EE+EEEEEE
Sbjct: 722 LAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 2/70 (2%)

Query: 22  EEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP--PPRVVSEE 79
           ++E       P +  S SG  D+E +E     EE EE      E    P     + ++EE
Sbjct: 547 DKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEE 606

Query: 80  HLRRYAPDPV 89
            L+   P P+
Sbjct: 607 DLQHLPPQPL 616



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEE 59
           E EEEEEEE    +++  +   V GP      E  E   +  +E
Sbjct: 759 EEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQE 802


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 33/65 (50%), Positives = 39/65 (60%), Gaps = 20/65 (30%)

Query: 18   EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE---APPPPR 74
            EEEEEEE                 D++EE+EEEEEEE+EEEEEEEEEEEEE      PPR
Sbjct: 1070 EEEEEEE-----------------DEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR 1112

Query: 75   VVSEE 79
            +   +
Sbjct: 1113 LTKPQ 1117



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 28/58 (48%), Positives = 35/58 (60%)

Query: 35   SSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVR 92
            S   S  +++EEDEEEEEEEEEEEE+EEEEEEEE       +     R   P  V ++
Sbjct: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIK 1122



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 28/51 (54%), Positives = 33/51 (64%)

Query: 18   EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
            +EE   E   +  SP++S      DD  + EEEEEEEEEEEEEEEEEE EE
Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEE 1371



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 24/47 (51%), Positives = 30/47 (63%)

Query: 22   EEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
            E    T         S    +++EE+E+EEEEEEEEEEEE+EEEEEE
Sbjct: 1050 ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEE 1096



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%)

Query: 3    ILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE----E 58
            ++ P   E +   E EEEEEEE        +      G    E++E E   E+E+    +
Sbjct: 1347 LIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLD 1406

Query: 59   EEEEEEEEEEAP 70
            + EEEEEE+E P
Sbjct: 1407 DHEEEEEEDEEP 1418



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 17/79 (21%)

Query: 18   EEEEEEEAATSSSSPSSSSSVSGPDDD-----------------EEDEEEEEEEEEEEEE 60
            E+EE+E  +T ++S  S + V   +                   E  +E  EEEEEEE+E
Sbjct: 1019 EKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDE 1078

Query: 61   EEEEEEEEAPPPPRVVSEE 79
            EEEEEEEE         EE
Sbjct: 1079 EEEEEEEEEEEDEEEEEEE 1097



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 20/52 (38%), Positives = 25/52 (48%)

Query: 6    PNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE 57
            P   E   + EL +E  EE                 +D+EE+EEEEEEEEEE
Sbjct: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 7/54 (12%)

Query: 14   ISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEE 67
            + + EEEEEE+   S +    +       DDE+D   E  E E+EE   E  +E
Sbjct: 1405 LDDHEEEEEEDEEPSHNEDHDA-------DDEDDSHMESAEVEKEELPRESFKE 1451



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 21/89 (23%), Positives = 38/89 (42%), Gaps = 21/89 (23%)

Query: 1    MSILLPNMAEFDTISELEEEEEEEAATSSSSPS---------SSSSVSGPDDDEEDEE-- 49
            +++  P     +   ++  EE++E +   +SPS          +     P ++   EE  
Sbjct: 1271 LNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETC 1330

Query: 50   ----------EEEEEEEEEEEEEEEEEEE 68
                      E+ E++  + EEEEEEEEE
Sbjct: 1331 APVSPNTSPGEKPEDDLIKPEEEEEEEEE 1359


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 33/63 (52%), Positives = 42/63 (66%), Gaps = 15/63 (23%)

Query: 7   NMAE-FDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEE 65
           NMA+   ++S+ E+EEEEE               G +++EE EEEEEE+EEEEEEEEEEE
Sbjct: 349 NMAKVLASLSDDEDEEEEE--------------EGEEEEEEAEEEEEEDEEEEEEEEEEE 394

Query: 66  EEE 68
           EEE
Sbjct: 395 EEE 397



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 27/57 (47%), Positives = 38/57 (66%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           +T+ E   E+ +E     +     +S+S  +D+EE+EE EEEEEE EEEEEE+EEEE
Sbjct: 331 NTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEE 387



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 18/40 (45%), Positives = 22/40 (55%)

Query: 49  EEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDP 88
           ++E+EEEEEE EEEEEE EE         EE       +P
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEP 398



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 19/46 (41%), Positives = 23/46 (50%)

Query: 50  EEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95
           ++E+EEEEEE EEEEEE E         EE       +    RG G
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQG 404


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 27/66 (40%), Positives = 38/66 (57%)

Query: 9  AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
          +E    SE E+ E       +       S +G + +EE E+EEEEEEEEE +EEEEEE++
Sbjct: 4  SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63

Query: 69 APPPPR 74
            PP +
Sbjct: 64 DRPPKK 69



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%)

Query: 8  MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66
          M++ +  +  EEE+ E ++    +       S    ++E+E E+EEEEEEEEE +EEEEE
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 67 EEAPPPPR 74
          E+   PP+
Sbjct: 61 EDDDRPPK 68



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 7  NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66
          N +E +      + EE E      S + S     P+D+EE    EEEEEE +EEEEEE++
Sbjct: 8  NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63

Query: 67 EEAPPPPR 74
          +  P  PR
Sbjct: 64 DRPPKKPR 71



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 21/64 (32%), Positives = 31/64 (48%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75
           E EE +EEE       P       G   DE D ++E E+E++ E+  E+  E+A     V
Sbjct: 50  EEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNV 109

Query: 76  VSEE 79
           V +E
Sbjct: 110 VLDE 113


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 27/66 (40%), Positives = 38/66 (57%)

Query: 9  AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
          +E    SE E+ E       +       S +G + +EE E+EEEEEEEEE +EEEEEE++
Sbjct: 4  SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63

Query: 69 APPPPR 74
            PP +
Sbjct: 64 DRPPKK 69



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%)

Query: 8  MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66
          M++ +  +  EEE+ E ++    +       S    ++E+E E+EEEEEEEEE +EEEEE
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 67 EEAPPPPR 74
          E+   PP+
Sbjct: 61 EDDDRPPK 68



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 7  NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66
          N +E +      + EE E      S + S     P+D+EE    EEEEEE +EEEEEE++
Sbjct: 8  NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63

Query: 67 EEAPPPPR 74
          +  P  PR
Sbjct: 64 DRPPKKPR 71



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 20/62 (32%), Positives = 32/62 (51%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVS 77
           EEEEEE+       P     +    D +++ E+E++ E+  E+  E+EE EA     VV 
Sbjct: 56  EEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVL 115

Query: 78  EE 79
           +E
Sbjct: 116 DE 117


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 27/66 (40%), Positives = 38/66 (57%)

Query: 9  AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
          +E    SE E+ E       +       S +G + +EE E+EEEEEEEEE +EEEEEE++
Sbjct: 4  SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63

Query: 69 APPPPR 74
            PP +
Sbjct: 64 DRPPKK 69



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%)

Query: 8  MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66
          M++ +  +  EEE+ E ++    +       S    ++E+E E+EEEEEEEEE +EEEEE
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 67 EEAPPPPR 74
          E+   PP+
Sbjct: 61 EDDDRPPK 68



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 7  NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66
          N +E +      + EE E      S + S     P+D+EE    EEEEEE +EEEEEE++
Sbjct: 8  NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63

Query: 67 EEAPPPPR 74
          +  P  PR
Sbjct: 64 DRPPKKPR 71



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 20/62 (32%), Positives = 32/62 (51%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVS 77
           EEEEEE+       P     +    D +++ E+E++ E+  E+  E+EE EA     VV 
Sbjct: 56  EEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVL 115

Query: 78  EE 79
           +E
Sbjct: 116 DE 117


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 27/66 (40%), Positives = 38/66 (57%)

Query: 9  AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
          +E    SE E+ E       +       S +G + +EE E+EEEEEEEEE +EEEEEE++
Sbjct: 4  SEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDD 63

Query: 69 APPPPR 74
            PP +
Sbjct: 64 DRPPKK 69



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 1/68 (1%)

Query: 8  MAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE-EEEEEE 66
          M++ +  +  EEE+ E ++    +       S    ++E+E E+EEEEEEEEE +EEEEE
Sbjct: 1  MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60

Query: 67 EEAPPPPR 74
          E+   PP+
Sbjct: 61 EDDDRPPK 68



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 7  NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66
          N +E +      + EE E      S + S     P+D+EE    EEEEEE +EEEEEE++
Sbjct: 8  NFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE----EEEEEEYDEEEEEEDD 63

Query: 67 EEAPPPPR 74
          +  P  PR
Sbjct: 64 DRPPKKPR 71



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 20/62 (32%), Positives = 32/62 (51%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVS 77
           EEEEEE+       P     +    D +++ E+E++ E+  E+  E+EE EA     VV 
Sbjct: 56  EEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVL 115

Query: 78  EE 79
           +E
Sbjct: 116 DE 117


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 26/36 (72%), Positives = 29/36 (80%)

Query: 44   DEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
            +EE+EEEEEEEEEEEEEEEE EEEE   PP+  S E
Sbjct: 1132 EEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSE 1167



 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 24/30 (80%), Positives = 28/30 (93%)

Query: 42   DDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71
            +++EE+EEEEEEEEEEEEEE EEEEEE PP
Sbjct: 1132 EEEEEEEEEEEEEEEEEEEEAEEEEEELPP 1161



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 26/36 (72%), Positives = 29/36 (80%)

Query: 43   DDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSE 78
            ++EE+EEEEEEEEEEEEEEE EEEEE  PP    SE
Sbjct: 1132 EEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSE 1167



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 18/37 (48%), Positives = 26/37 (70%)

Query: 45   EEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHL 81
            ++ ++++++EEEEEEEEEEEEEEE         EE L
Sbjct: 1123 QQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL 1159



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 15/42 (35%), Positives = 27/42 (64%)

Query: 45   EEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP 86
            ++ +++++++++EEEEEEEEEEEE        +EE      P
Sbjct: 1120 QQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPP 1161



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 17/71 (23%)

Query: 16   ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRV 75
            E EEEEEEE                 +++EE+EEEEE EEEEEE   +    E      +
Sbjct: 1132 EEEEEEEEE-----------------EEEEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174

Query: 76   VSEEHLRRYAP 86
              EE L +  P
Sbjct: 1175 NPEEVLEQPQP 1185



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 13/52 (25%), Positives = 26/52 (50%)

Query: 6    PNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEE 57
            PN  ++      +++++++                 +++EE+EEE EEEEEE
Sbjct: 1107 PNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 26/54 (48%), Positives = 34/54 (62%)

Query: 15  SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           + L+  E      S   PS+S + +  +DDEE +EEEEEEEEEEEEE  + EEE
Sbjct: 411 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 464



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDD---DEEDEEEEEEEEEEEEEEEEEE 65
           A     S    +  E +  S   PS  +S   P     + +DE++EE +EEEEEEEEEEE
Sbjct: 396 ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEE 455

Query: 66  EE 67
           EE
Sbjct: 456 EE 457



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 16/90 (17%)

Query: 10  EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE----EE 65
           E D   E EEEEEEE AT S            ++D E  +E +E++EEE+EEEE    ++
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEE----------EEDLEQMQEGQEDDEEEDEEEEAAAGKD 491

Query: 66  EEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95
            +++P     +S E  +   P   + R +G
Sbjct: 492 GDKSPMSSLQISNE--KNLEPGKQISRSSG 519



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/60 (36%), Positives = 30/60 (50%)

Query: 24  EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRR 83
           EA+  S    S  +  G       E ++E++EE +EEEEEEEEEE         EE L +
Sbjct: 410 EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 469



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 9/79 (11%)

Query: 5   LPNMAEFDTISELEEEEEEEAA--TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62
           L  M E     E E+EEEE AA      SP SS  +S       +E+  E  ++      
Sbjct: 467 LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS-------NEKNLEPGKQISRSSG 519

Query: 63  EEEEEEAPPPPRVVSEEHL 81
           E++ +     P ++SEE L
Sbjct: 520 EQQNKGRIVSPSLLSEEPL 538


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 26/54 (48%), Positives = 34/54 (62%)

Query: 15  SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           + L+  E      S   PS+S + +  +DDEE +EEEEEEEEEEEEE  + EEE
Sbjct: 411 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 464



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDD---DEEDEEEEEEEEEEEEEEEEEE 65
           A     S    +  E +  S   PS  +S   P     + +DE++EE +EEEEEEEEEEE
Sbjct: 396 ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEE 455

Query: 66  EE 67
           EE
Sbjct: 456 EE 457



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 16/90 (17%)

Query: 10  EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE----EE 65
           E D   E EEEEEEE AT S            ++D E  +E +E++EEE+EEEE    ++
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEE----------EEDLEQMQEGQEDDEEEDEEEEAAAGKD 491

Query: 66  EEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95
            +++P     +S E  +   P   + R +G
Sbjct: 492 GDKSPMSSLQISNE--KNLEPGKQISRSSG 519



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/60 (36%), Positives = 30/60 (50%)

Query: 24  EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRR 83
           EA+  S    S  +  G       E ++E++EE +EEEEEEEEEE         EE L +
Sbjct: 410 EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 469



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 9/79 (11%)

Query: 5   LPNMAEFDTISELEEEEEEEAA--TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62
           L  M E     E E+EEEE AA      SP SS  +S       +E+  E  ++      
Sbjct: 467 LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS-------NEKNLEPGKQISRSSG 519

Query: 63  EEEEEEAPPPPRVVSEEHL 81
           E++ +     P ++SEE L
Sbjct: 520 EQQNKGRIVSPSLLSEEPL 538


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 26/54 (48%), Positives = 34/54 (62%)

Query: 15  SELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           + L+  E      S   PS+S + +  +DDEE +EEEEEEEEEEEEE  + EEE
Sbjct: 423 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEE 476



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDD---DEEDEEEEEEEEEEEEEEEEEE 65
           A     S    +  E +  S   PS  +S   P     + +DE++EE +EEEEEEEEEEE
Sbjct: 408 ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEE 467

Query: 66  EE 67
           EE
Sbjct: 468 EE 469



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 16/90 (17%)

Query: 10  EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE----EE 65
           E D   E EEEEEEE AT S            ++D E  +E +E++EEE+EEEE    ++
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEE----------EEDLEQMQEGQEDDEEEDEEEEAAAGKD 503

Query: 66  EEEAPPPPRVVSEEHLRRYAPDPVLVRGAG 95
            +++P     +S E  +   P   + R +G
Sbjct: 504 GDKSPMSSLQISNE--KNLEPGKQISRSSG 531



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/60 (36%), Positives = 30/60 (50%)

Query: 24  EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRR 83
           EA+  S    S  +  G       E ++E++EE +EEEEEEEEEE         EE L +
Sbjct: 422 EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 481



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 9/79 (11%)

Query: 5   LPNMAEFDTISELEEEEEEEAA--TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62
           L  M E     E E+EEEE AA      SP SS  +S       +E+  E  ++      
Sbjct: 479 LEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS-------NEKNLEPGKQISRSSG 531

Query: 63  EEEEEEAPPPPRVVSEEHL 81
           E++ +     P ++SEE L
Sbjct: 532 EQQNKGRIVSPSLLSEEPL 550


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 25/64 (39%), Positives = 41/64 (64%)

Query: 9    AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
            AE +      +++++         SSS + S  +++EE++EEEEEEEEEEEEEEE+E ++
Sbjct: 1372 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431

Query: 69   APPP 72
            +  P
Sbjct: 1432 SKSP 1435



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 5/64 (7%)

Query: 15   SELEE-----EEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69
            +ELEE     +++++         SSS      ++EE+E+EEEEEEEEEEEEEEE+E + 
Sbjct: 1372 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431

Query: 70   PPPP 73
               P
Sbjct: 1432 SKSP 1435



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 20/51 (39%), Positives = 27/51 (52%)

Query: 18   EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
            ++ E EE   S         +   +D   + +   EEEEEE+EEEEEEEEE
Sbjct: 1370 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 17/60 (28%), Positives = 36/60 (60%)

Query: 23   EEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLR 82
            +E ++S +  +S       +++EE+EEEEEEEEE+E ++ +   +      +++ ++ LR
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLR 1452



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 12/79 (15%)

Query: 13   TISELEEEEEEEAATSSSSPSSSSSVSG-------PDDDEEDEEEEEEEEEEEEEEEEEE 65
            T+S+ E  EE++     + P     V G        +D E+ + +E    EE  E E+E+
Sbjct: 1308 TVSDGESGEEKK-----TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1362

Query: 66   EEEAPPPPRVVSEEHLRRY 84
                    +   EE+ R Y
Sbjct: 1363 RPRTRSAKKAELEENQRSY 1381



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 8/71 (11%)

Query: 16   ELEEEEEEEAATSSSSPSSSSSVSG--------PDDDEEDEEEEEEEEEEEEEEEEEEEE 67
            E EEEEEEE      +  S S   G         DD    E +   +EEEE  +   E E
Sbjct: 1414 EEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERE 1473

Query: 68   EAPPPPRVVSE 78
                  R V E
Sbjct: 1474 REREKLREVIE 1484


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 25/64 (39%), Positives = 41/64 (64%)

Query: 9    AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
            AE +      +++++         SSS + S  +++EE++EEEEEEEEEEEEEEE+E ++
Sbjct: 1410 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469

Query: 69   APPP 72
            +  P
Sbjct: 1470 SKSP 1473



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 5/64 (7%)

Query: 15   SELEE-----EEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69
            +ELEE     +++++         SSS      ++EE+E+EEEEEEEEEEEEEEE+E + 
Sbjct: 1410 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469

Query: 70   PPPP 73
               P
Sbjct: 1470 SKSP 1473



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 20/51 (39%), Positives = 27/51 (52%)

Query: 18   EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
            ++ E EE   S         +   +D   + +   EEEEEE+EEEEEEEEE
Sbjct: 1408 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1458



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 17/60 (28%), Positives = 36/60 (60%)

Query: 23   EEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLR 82
            +E ++S +  +S       +++EE+EEEEEEEEE+E ++ +   +      +++ ++ LR
Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLR 1490



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 12/79 (15%)

Query: 13   TISELEEEEEEEAATSSSSPSSSSSVSG-------PDDDEEDEEEEEEEEEEEEEEEEEE 65
            T+S+ E  EE++     + P     V G        +D E+ + +E    EE  E E+E+
Sbjct: 1346 TVSDGESGEEKK-----TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1400

Query: 66   EEEAPPPPRVVSEEHLRRY 84
                    +   EE+ R Y
Sbjct: 1401 RPRTRSAKKAELEENQRSY 1419



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 8/71 (11%)

Query: 16   ELEEEEEEEAATSSSSPSSSSSVSG--------PDDDEEDEEEEEEEEEEEEEEEEEEEE 67
            E EEEEEEE      +  S S   G         DD    E +   +EEEE  +   E E
Sbjct: 1452 EEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERE 1511

Query: 68   EAPPPPRVVSE 78
                  R V E
Sbjct: 1512 REREKLREVIE 1522



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 18/85 (21%)

Query: 17  LEEEEEEEAATSSSSPSSSSSVSG-----------PDDDEEDEEEEEEEEEEEEEEEEEE 65
           +E  +EE  ++S  S SS SS S             DD++  ++E   E+   E  E + 
Sbjct: 57  MENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDI 116

Query: 66  EEEAPPPPRVVSEEHLRRYAPDPVL 90
             ++ P   V+ +       P+PVL
Sbjct: 117 TMQSLPKGTVIVQ-------PEPVL 134


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 26/51 (50%), Positives = 31/51 (60%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           +E+EE+E                 D+D ED E+EEEEEEEEEEEEEEEE E
Sbjct: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 30/70 (42%), Positives = 36/70 (51%), Gaps = 13/70 (18%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEE-------------EEEEE 58
           + + E EE+E EE +  +  P          D EE+EE EEE             EEEEE
Sbjct: 97  EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156

Query: 59  EEEEEEEEEE 68
           EEEEEEEEEE
Sbjct: 157 EEEEEEEEEE 166



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 9/78 (11%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEE---------EEEE 62
           D   +++E+EE+E    S            D++ + EEEEE EEE+E         E+EE
Sbjct: 94  DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153

Query: 63  EEEEEEAPPPPRVVSEEH 80
           EEEEEE        +E+H
Sbjct: 154 EEEEEEEEEEEEEENEDH 171



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 22/51 (43%), Positives = 29/51 (56%)

Query: 16  ELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEE 66
           E +EE + E               G D ++E+EEEEEEEEEEEEEE E+ +
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 21/52 (40%), Positives = 27/52 (51%)

Query: 12  DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE 63
           D   E  + EEEE                 D++EE+EEEEEEEEEEE E+ +
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 19/51 (37%), Positives = 26/51 (50%)

Query: 10  EFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60
           E D   + EEEEE E                 +++EE+EEEEEEEE E+ +
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 19/51 (37%), Positives = 26/51 (50%)

Query: 29  SSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
           SSS        G +D +E EE+E EE  E+ +E  +E+EE     R   EE
Sbjct: 84  SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEE 134



 Score = 35.0 bits (79), Expect = 0.052
 Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 10/53 (18%)

Query: 26  ATSSSSPSSSSSVSGPDDDEEDEEEEEE----------EEEEEEEEEEEEEEE 68
           A SSS      S    D DE++E+E EE          E+EE+EE + EEEEE
Sbjct: 82  ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEE 134



 Score = 31.2 bits (69), Expect = 0.75
 Identities = 15/53 (28%), Positives = 28/53 (52%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAP 70
           +++ +E A         + S S  + D+ D  E+ +E+EE+E EE  E+ + P
Sbjct: 65  DKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 13/54 (24%), Positives = 29/54 (53%)

Query: 18  EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71
           ++++ +E A      +  +  S  D+ ++ +  E+ +E+EE+E EE  E+   P
Sbjct: 64  QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 13/54 (24%), Positives = 28/54 (51%)

Query: 19  EEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPP 72
           ++++ +       P +  + S   D+ +D +  E+ +E+EE+E EE  E+   P
Sbjct: 64  QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117


>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
          Length = 285

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 25/63 (39%), Positives = 35/63 (55%)

Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71
          + + E EEEE+EEAA      ++        + EE   EE+EEEEE +E E+   EE+ P
Sbjct: 6  EVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 65

Query: 72 PPR 74
           PR
Sbjct: 66 KPR 68



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 17/38 (44%), Positives = 21/38 (55%)

Query: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
          D +E  EE EEEE+EE   EE+EE  E        +EE
Sbjct: 3  DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEE 40



 Score = 31.2 bits (69), Expect = 0.75
 Identities = 18/44 (40%), Positives = 22/44 (50%)

Query: 44 DEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPD 87
          D E+  EE EEEE+EE   EE+EE A       +E    R   D
Sbjct: 3  DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEED 46


>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
          Length = 288

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 25/63 (39%), Positives = 35/63 (55%)

Query: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71
          + + E EEEE+EEAA      ++        + EE   EE+EEEEE +E E+   EE+ P
Sbjct: 6  EVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 65

Query: 72 PPR 74
           PR
Sbjct: 66 KPR 68



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 17/38 (44%), Positives = 21/38 (55%)

Query: 42 DDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
          D +E  EE EEEE+EE   EE+EE  E        +EE
Sbjct: 3  DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEE 40



 Score = 31.2 bits (69), Expect = 0.75
 Identities = 18/44 (40%), Positives = 22/44 (50%)

Query: 44 DEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPD 87
          D E+  EE EEEE+EE   EE+EE A       +E    R   D
Sbjct: 3  DIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEED 46


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 29/68 (42%), Positives = 43/68 (63%)

Query: 1   MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60
           +++L   +AE     E EE E   AA  +++ + +++ +      EDEEEEE+EEEEE+E
Sbjct: 175 LNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKE 234

Query: 61  EEEEEEEE 68
           EEEEE EE
Sbjct: 235 EEEEEGEE 242



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 3/87 (3%)

Query: 3   ILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEE 62
           I++ +  E +   E E+EEEEE               G  + EE EEEEEEEEEEEEEE+
Sbjct: 217 IVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276

Query: 63  ---EEEEEEAPPPPRVVSEEHLRRYAP 86
               +E+++    P  V    LR   P
Sbjct: 277 IKAFQEKQKRWQQPTGVRSWRLREMKP 303



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 26/60 (43%), Positives = 31/60 (51%)

Query: 9   AEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
           AE   + + EEEE+EE               G ++ EE     E EE EEEEEEEEEEEE
Sbjct: 214 AEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 24/65 (36%), Positives = 42/65 (64%)

Query: 4   LLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE 63
           LL  + E+    + ++E EE  A ++++ +++++ +     E    E+EEEEE+EEEEE+
Sbjct: 174 LLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEK 233

Query: 64  EEEEE 68
           EEEEE
Sbjct: 234 EEEEE 238


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,399,874
Number of Sequences: 37866
Number of extensions: 728160
Number of successful extensions: 68639
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1704
Number of HSP's successfully gapped in prelim test: 288
Number of HSP's that attempted gapping in prelim test: 14664
Number of HSP's gapped (non-prelim): 23313
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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