Guide to the Human Genome
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Search of human proteins with 154707916

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154707916 glutathione S-transferase, C-terminal domain
containing isoform 2 [Homo sapiens]
         (546 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154707916 glutathione S-transferase, C-terminal domain contai...  1109   0.0  
gi|149588660 glutathione S-transferase, C-terminal domain contai...  1003   0.0  
gi|4758862 eukaryotic translation elongation factor 1 epsilon 1 ...    38   0.021
gi|87299628 biorientation of chromosomes in cell division 1-like...    33   0.51 
gi|110349719 titin isoform N2-A [Homo sapiens]                         33   0.67 
gi|110349717 titin isoform novex-2 [Homo sapiens]                      33   0.67 
gi|110349713 titin isoform novex-1 [Homo sapiens]                      33   0.67 
gi|110349715 titin isoform N2-B [Homo sapiens]                         33   0.67 
gi|8659574 transcription factor E3 [Homo sapiens]                      33   0.67 
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    32   1.5  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    32   1.5  
gi|9966827 PEST proteolytic signal containing nuclear protein [H...    32   1.5  
gi|33188443 microfilament and actin filament cross-linker protei...    32   2.0  
gi|33188445 microfilament and actin filament cross-linker protei...    32   2.0  
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    31   2.5  
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               31   3.3  
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                    31   3.3  
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    30   4.3  
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]            30   4.3  
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    30   4.3  
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    30   4.3  
gi|156564240 coiled-coil domain containing 104 [Homo sapiens]          30   4.3  
gi|87162461 fragile X mental retardation 2 [Homo sapiens]              30   5.7  
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           30   5.7  
gi|239751532 PREDICTED: similar to vacuolar protein sorting 53 (...    30   7.4  
gi|239746043 PREDICTED: hypothetical protein XP_002343642 [Homo ...    30   7.4  
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                 30   7.4  
gi|53829385 leucine rich repeat containing 37B [Homo sapiens]          30   7.4  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    29   9.7  

>gi|154707916 glutathione S-transferase, C-terminal domain
           containing isoform 2 [Homo sapiens]
          Length = 546

 Score = 1109 bits (2868), Expect = 0.0
 Identities = 546/546 (100%), Positives = 546/546 (100%)

Query: 1   MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSQWT 60
           MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSQWT
Sbjct: 1   MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSQWT 60

Query: 61  RLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADG 120
           RLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADG
Sbjct: 61  RLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADG 120

Query: 121 VGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPSHIRKAKA 180
           VGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPSHIRKAKA
Sbjct: 121 VGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPSHIRKAKA 180

Query: 181 SDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPG 240
           SDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPG
Sbjct: 181 SDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPG 240

Query: 241 VKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGGPRPTMAKLMEKGIE 300
           VKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGGPRPTMAKLMEKGIE
Sbjct: 241 VKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGGPRPTMAKLMEKGIE 300

Query: 301 VMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDRIVD 360
           VMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDRIVD
Sbjct: 301 VMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDRIVD 360

Query: 361 FCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNIWFIQANMEYFTGMF 420
           FCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNIWFIQANMEYFTGMF
Sbjct: 361 FCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNIWFIQANMEYFTGMF 420

Query: 421 NIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFPKSEQFKKTLSYKEH 480
           NIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFPKSEQFKKTLSYKEH
Sbjct: 421 NIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFPKSEQFKKTLSYKEH 480

Query: 481 MILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQVISMEPESCSPKNNM 540
           MILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQVISMEPESCSPKNNM
Sbjct: 481 MILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQVISMEPESCSPKNNM 540

Query: 541 IVGVPI 546
           IVGVPI
Sbjct: 541 IVGVPI 546


>gi|149588660 glutathione S-transferase, C-terminal domain
           containing isoform 1 [Homo sapiens]
          Length = 633

 Score = 1003 bits (2594), Expect = 0.0
 Identities = 495/500 (99%), Positives = 495/500 (99%)

Query: 47  KICLVVTKEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDD 106
           K CL    EVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDD
Sbjct: 134 KTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDD 193

Query: 107 KLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPA 166
           KLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPA
Sbjct: 194 KLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPA 253

Query: 167 TTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFP 226
           TTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFP
Sbjct: 254 TTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFP 313

Query: 227 LLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGG 286
           LLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGG
Sbjct: 314 LLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGG 373

Query: 287 PRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVY 346
           PRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVY
Sbjct: 374 PRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVY 433

Query: 347 VVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNI 406
           VVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNI
Sbjct: 434 VVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNI 493

Query: 407 WFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFP 466
           WFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFP
Sbjct: 494 WFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFP 553

Query: 467 KSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQV 526
           KSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQV
Sbjct: 554 KSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQV 613

Query: 527 ISMEPESCSPKNNMIVGVPI 546
           ISMEPESCSPKNNMIVGVPI
Sbjct: 614 ISMEPESCSPKNNMIVGVPI 633



 Score =  122 bits (306), Expect = 8e-28
 Identities = 61/85 (71%), Positives = 68/85 (80%)

Query: 1  MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSQWT 60
          MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVS+ +
Sbjct: 1  MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDS 60

Query: 61 RLCELTIPLAIENFLRESSDQPPTI 85
           L    +   +E  +    + PP +
Sbjct: 61 SLLRDDLIQDVEIQIISRQELPPIV 85


>gi|4758862 eukaryotic translation elongation factor 1 epsilon 1
           isoform 1 [Homo sapiens]
          Length = 174

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 187 EHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPGVK 242
           + V+  G  FTLADI+L   +H F+V ++ +  EK +    ++ W+  IQ  PG++
Sbjct: 104 DKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLN---VSRWFCHIQHYPGIR 156


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 27/141 (19%)

Query: 79  SDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQE 138
           SD   T+      + K+  E +     ++ + ++ ++QKA+      TKG+ +S V  +E
Sbjct: 484 SDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEE 543

Query: 139 TS-EGLDSSS----------KSLELKVAFS----------------KLTVQEEPATTNRE 171
           +S + L+  +          K LE KVA S                K   +E+   T + 
Sbjct: 544 SSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKT 603

Query: 172 PSHIRKAKASDLPPLEHVFAE 192
             H  K K S    L+HV A+
Sbjct: 604 SEHCEKEKISSSKELKHVHAK 624


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 305   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 360
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 16552 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 16611

Query: 361   FCSGGGHVGI-VLAHML--PSCQVT 382
                  G VG   LAH L   SC++T
Sbjct: 16612 VLDVPGPVGTPFLAHNLTNESCKLT 16636


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 305   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 360
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 10247 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 10306

Query: 361   FCSGGGHVGI-VLAHML--PSCQVT 382
                  G VG   LAH L   SC++T
Sbjct: 10307 VLDVPGPVGTPFLAHNLTNESCKLT 10331


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 305   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 360
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 10180 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 10239

Query: 361   FCSGGGHVGI-VLAHML--PSCQVT 382
                  G VG   LAH L   SC++T
Sbjct: 10240 VLDVPGPVGTPFLAHNLTNESCKLT 10264


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 305   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 360
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 10055 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 10114

Query: 361   FCSGGGHVGI-VLAHML--PSCQVT 382
                  G VG   LAH L   SC++T
Sbjct: 10115 VLDVPGPVGTPFLAHNLTNESCKLT 10139


>gi|8659574 transcription factor E3 [Homo sapiens]
          Length = 575

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 78  SSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPL 125
           S   P  +P E+L+++  L  P R H   + RRQ++KQ  +  +GP L
Sbjct: 165 SRPPPAQVPREVLKVQTHLENPTRYHL-QQARRQQVKQYLSTTLGPKL 211


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 33/133 (24%), Positives = 66/133 (49%), Gaps = 14/133 (10%)

Query: 38   LSYCDCKIFKICLVVTKEVSQWTRLCELTIPLAIENFLRESSDQP--PTIPVEILQLEKK 95
            LS+   +     L  TKE S+ T     +I +  EN ++E+S+ P  P     + Q  K 
Sbjct: 1374 LSFSSLESLSSELEQTKEFSKRTE----SIAVQAENLVKEASEIPLGPQNKQLLQQQAKS 1429

Query: 96   LSEPVRVHND---DKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSE--GLDSSSKSL 150
            + E V+   D   + ++  ++ + K D  G   +  +  S   T++  E   L++SS ++
Sbjct: 1430 IKEQVKKLEDTLEEDIKTMEMVKTKWDHFG---SNFETLSVWITEKEKELNALETSSSAM 1486

Query: 151  ELKVAFSKLTVQE 163
            +++++  K+T+QE
Sbjct: 1487 DMQISQIKVTIQE 1499


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 33/133 (24%), Positives = 66/133 (49%), Gaps = 14/133 (10%)

Query: 38   LSYCDCKIFKICLVVTKEVSQWTRLCELTIPLAIENFLRESSDQP--PTIPVEILQLEKK 95
            LS+   +     L  TKE S+ T     +I +  EN ++E+S+ P  P     + Q  K 
Sbjct: 1367 LSFSSLESLSSELEQTKEFSKRTE----SIAVQAENLVKEASEIPLGPQNKQLLQQQAKS 1422

Query: 96   LSEPVRVHND---DKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSE--GLDSSSKSL 150
            + E V+   D   + ++  ++ + K D  G   +  +  S   T++  E   L++SS ++
Sbjct: 1423 IKEQVKKLEDTLEEDIKTMEMVKTKWDHFG---SNFETLSVWITEKEKELNALETSSSAM 1479

Query: 151  ELKVAFSKLTVQE 163
            +++++  K+T+QE
Sbjct: 1480 DMQISQIKVTIQE 1492


>gi|9966827 PEST proteolytic signal containing nuclear protein [Homo
           sapiens]
          Length = 178

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 6/64 (9%)

Query: 114 KQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPS 173
           K Q+A   G P  + +   K  T  +S G +SSS+S E      K + +EE A    +P+
Sbjct: 13  KSQRAGAAGGPEEEAEKPVKTKTVSSSNGGESSSRSAE------KRSAEEEAADLPTKPT 66

Query: 174 HIRK 177
            I K
Sbjct: 67  KISK 70


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 9/97 (9%)

Query: 59   WTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKA 118
            W + CE  +    E  L ++    P +  E L   K+L E +  H     + QK+ +   
Sbjct: 2449 WMQACEANV----EKLLSDTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIM 2504

Query: 119  DGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVA 155
            +  G P     A    H QET++ + S  +SL   +A
Sbjct: 2505 EIEGEP-----APDHRHVQETTDSILSHFQSLSYSLA 2536


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 9/97 (9%)

Query: 59   WTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKA 118
            W + CE  +    E  L ++    P +  E L   K+L E +  H     + QK+ +   
Sbjct: 1947 WMQACEANV----EKLLSDTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIM 2002

Query: 119  DGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVA 155
            +  G P     A    H QET++ + S  +SL   +A
Sbjct: 2003 EIEGEP-----APDHRHVQETTDSILSHFQSLSYSLA 2034


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
           [Homo sapiens]
          Length = 3969

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 7/88 (7%)

Query: 106 DKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEP 165
           DK++++  K  +     PP   G      H ++ SE L   +K   LK       ++  P
Sbjct: 208 DKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISE-LPKGNKEDSLK------KIKRTP 260

Query: 166 ATTNREPSHIRKAKASDLPPLEHVFAEG 193
           + T ++ + I+K +A  L PL+  F  G
Sbjct: 261 SATFQQATKIKKLRAGKLSPLKSKFKTG 288


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 25/132 (18%)

Query: 71   IENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKA 130
            + +F ++ SDQ    PV+ ++  K L                L    ++ + P   KG A
Sbjct: 1043 VHSFQQDKSDQRENSPVQSIRSPKSL----------------LFGAMSEMISPS-EKGSA 1085

Query: 131  KSKVHTQETSE-----GLDSSSKSLELKVAFSKLT---VQEEPATTNREPSHIRKAKASD 182
            + K  ++ T +        +  KS +  ++FSK T   +   P T    P  ++K+ A  
Sbjct: 1086 RMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKM 1145

Query: 183  LPPLEHVFAEGL 194
             P  +  F E L
Sbjct: 1146 TPTKQAAFKESL 1157


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 78   SSDQPPTIPVEILQL---EKKLSEPVRVHNDDKLRRQKLKQQKADGVGP 123
            +SD+ P  P+E+ +L   E  L  PV+      L  Q  K QK DG  P
Sbjct: 1505 ASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKGDGDRP 1553


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 12/84 (14%)

Query: 104 NDDKLRRQKLKQQKADGVGPPLTKGKAKSKV-----HTQETSEGLDSSSKSLELKVAFSK 158
           +++K R  + +Q + DG      K K K KV         + EG DSSS S E ++    
Sbjct: 726 DEEKGRGSESEQSEEDG------KRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSES 779

Query: 159 LTVQEEPATTNRE-PSHIRKAKAS 181
              Q EPA+ +R+ P   + A A+
Sbjct: 780 EEEQLEPASWSRKTPPSSKSAPAT 803


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 6/77 (7%)

Query: 311  WTLDWNVLPAAVSPKEGKMSSDRALRKQQ--QLNNLVYVVTNQAKPGDR--IVDFCSGGG 366
            WT D  +  + +  +EG  ++ +   K+Q  QLN L+ ++  +  PGDR  I+  C+   
Sbjct: 1755 WTTDVGIAFSRL--EEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDV 1812

Query: 367  HVGIVLAHMLPSCQVTL 383
            H   V+A ++   QV +
Sbjct: 1813 HARDVVAKLISQKQVVV 1829


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 7/88 (7%)

Query: 76   RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVH 135
            + + +   T PV+  +++K  S+ V+    +KL  ++ K +K +    PL     K K  
Sbjct: 1060 KSAKEHQETKPVKEEKVKKDYSKDVK---SEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK 1116

Query: 136  TQETSEGLDSSSKSLELKVAFSKLTVQE 163
            T+E  +G+D   +S  +K+  SKL V E
Sbjct: 1117 TEE--KGVDKDFESSSMKI--SKLEVTE 1140


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 7/88 (7%)

Query: 76   RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVH 135
            + + +   T PV+  +++K  S+ V+    +KL  ++ K +K +    PL     K K  
Sbjct: 1094 KSAKEHQETKPVKEEKVKKDYSKDVK---SEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK 1150

Query: 136  TQETSEGLDSSSKSLELKVAFSKLTVQE 163
            T+E  +G+D   +S  +K+  SKL V E
Sbjct: 1151 TEE--KGVDKDFESSSMKI--SKLEVTE 1174


>gi|156564240 coiled-coil domain containing 104 [Homo sapiens]
          Length = 342

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 36/178 (20%), Positives = 72/178 (40%), Gaps = 9/178 (5%)

Query: 23  EGCIFPL---HTSVTLF--LLSYCDCKIFKICLVVTKEVSQWTRLCELTIPL--AIENFL 75
           E C  PL   HTS  +   +L+  D  IFK  ++V K +    +   +       + + L
Sbjct: 81  EACTSPLAKTHTSQAILQPVLAAEDFTIFK-AMMVQKNIEMQLQAIRIIQERNGVLPDCL 139

Query: 76  RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVH 135
            + SD    +  E +++ +++    +   D +  R++ KQ        P T   +++ + 
Sbjct: 140 TDGSDVVSDLEHEEMKILREVLRKSKEEYDQEEERKRKKQLSEAKTEEP-TVHSSEAAIM 198

Query: 136 TQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPSHIRKAKASDLPPLEHVFAEG 193
                +G   +    E+K+ F+  +++       R  +     K   +P LEH   EG
Sbjct: 199 NNSQGDGEHFAHPPSEVKMHFANQSIEPLGRKVERSETSSLPQKDLKIPGLEHASIEG 256


>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
          Length = 1311

 Score = 30.0 bits (66), Expect = 5.7
 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 5/105 (4%)

Query: 71  IENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTK--- 127
           +E+ L+ SSD+    PV+ L  +   +E  +     K R   +    A    PP  +   
Sbjct: 423 LEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKPRNNPVNPPLATPQPPPAVQASG 482

Query: 128 --GKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNR 170
             G +     + E+    +SS+   E   A    T + EP +TN+
Sbjct: 483 GSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNK 527


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 30.0 bits (66), Expect = 5.7
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 3/102 (2%)

Query: 64   ELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKL-RRQKLKQQKADGVG 122
            +LT    I+  LRE   +      + +Q +K   E  R   +D+L RR K  +Q      
Sbjct: 2314 KLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEE 2373

Query: 123  PPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEE 164
            PP+ K +A +K     T   +D   +++E K++  + T+ E+
Sbjct: 2374 PPMKKSQAANKQVPPLTK--VDVKMETIERKISVREQTMSEK 2413


>gi|239751532 PREDICTED: similar to vacuolar protein sorting 53
           (yeast) (predicted) [Homo sapiens]
          Length = 188

 Score = 29.6 bits (65), Expect = 7.4
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 8/118 (6%)

Query: 165 PATTNREPSHIRKAKASDLPPLEHVFAEGLY---FTLADIVLLPCIHHFLVIISRKFSEK 221
           P    RE  HI              F +G+    + LA++V  P     LV++   + + 
Sbjct: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP--QELLVVLVDNYIKL 67

Query: 222 LVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLP-KLLTTSTEQHPNLCEVPGVEEQ 278
             +    A  +++I ++ G+K       ++FLHLP  +L    E   +L  +P   EQ
Sbjct: 68  FTDCNTEA--FRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPTPEQ 123


>gi|239746043 PREDICTED: hypothetical protein XP_002343642 [Homo
           sapiens]
          Length = 188

 Score = 29.6 bits (65), Expect = 7.4
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 8/118 (6%)

Query: 165 PATTNREPSHIRKAKASDLPPLEHVFAEGLY---FTLADIVLLPCIHHFLVIISRKFSEK 221
           P    RE  HI              F +G+    + LA++V  P     LV++   + + 
Sbjct: 10  PKLLGREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP--QELLVVLVDNYIKL 67

Query: 222 LVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLP-KLLTTSTEQHPNLCEVPGVEEQ 278
             +    A  +++I ++ G+K       ++FLHLP  +L    E   +L  +P   EQ
Sbjct: 68  FTDCNTEA--FRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPTPEQ 123


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score = 29.6 bits (65), Expect = 7.4
 Identities = 15/77 (19%), Positives = 39/77 (50%)

Query: 88  EILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSS 147
           E+L+  +K  E ++ +N   + + K++QQ+     P + + + K+++   + S  ++   
Sbjct: 772 ELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGG 831

Query: 148 KSLELKVAFSKLTVQEE 164
            + E +    + + QEE
Sbjct: 832 SAAEQREKIKQFSQQEE 848


>gi|53829385 leucine rich repeat containing 37B [Homo sapiens]
          Length = 947

 Score = 29.6 bits (65), Expect = 7.4
 Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 38/182 (20%)

Query: 20  HQTEGCIFPLHTSV---TLFLLSYCDCKIFKICLVVTKEVSQWTRLCELTIPLAIENFLR 76
           HQ +  + PL + V   T F++S  + K         K++++   L E+   + I + L 
Sbjct: 166 HQADEILVPLDSKVSRPTKFVVSPKNLK---------KDLAERWSLPEI---VGIPHQLS 213

Query: 77  ESSDQPPTIPVEILQLEK----KLSEPVRVHNDDKLRRQKLKQQKADGVGPP----LTKG 128
           +   Q  T+P + L ++      L   +RV+ D+               GPP    L++ 
Sbjct: 214 KPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEP-------------PGPPEQVGLSQF 260

Query: 129 KAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPSHIRKAKASDL--PPL 186
             + K    ET E + SSS   E      +L  + EP+T    P+   ++    L   PL
Sbjct: 261 HLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPL 320

Query: 187 EH 188
            H
Sbjct: 321 NH 322


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 29.3 bits (64), Expect = 9.7
 Identities = 26/106 (24%), Positives = 47/106 (44%), Gaps = 5/106 (4%)

Query: 76   RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVG--PPLTKGKAKSK 133
            +ES  +  ++  EILQL+++L+   R     +  R +L  +  +       L   K + +
Sbjct: 1676 KESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE 1735

Query: 134  VHTQETSEGLDSSSKSLE-LKVAFSKLTVQEEPATTNREPSHIRKA 178
                +  E L+    ++E L   F K T+Q +  T N E +  R A
Sbjct: 1736 ARIAQLEEELEEEQSNMELLNDRFRKTTLQVD--TLNAELAAERSA 1779


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,608,762
Number of Sequences: 37866
Number of extensions: 971640
Number of successful extensions: 2493
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2465
Number of HSP's gapped (non-prelim): 52
length of query: 546
length of database: 18,247,518
effective HSP length: 107
effective length of query: 439
effective length of database: 14,195,856
effective search space: 6231980784
effective search space used: 6231980784
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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