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Search of human proteins with 154448890
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154448890 THO complex 1 [Homo sapiens]
(657 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154448890 THO complex 1 [Homo sapiens] 1332 0.0
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 52 2e-06
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 52 2e-06
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 48 3e-05
gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinas... 39 0.012
gi|13378137 TNFRSF1A-associated via death domain [Homo sapiens] 39 0.020
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.058
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 35 0.22
gi|148612801 KIAA1009 protein [Homo sapiens] 35 0.29
gi|34304368 dystrobrevin binding protein 1 isoform b [Homo sapiens] 34 0.37
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 33 0.64
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 33 0.64
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 33 0.64
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 33 0.64
gi|47578107 delangin isoform B [Homo sapiens] 33 1.1
gi|47578105 delangin isoform A [Homo sapiens] 33 1.1
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 32 1.4
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 32 1.4
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 32 1.4
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 32 1.4
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 32 1.4
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 32 1.4
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 32 1.4
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 32 1.4
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 32 1.4
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 32 1.4
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 32 2.4
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 32 2.4
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 32 2.4
gi|34304370 dystrobrevin binding protein 1 isoform c [Homo sapiens] 32 2.4
>gi|154448890 THO complex 1 [Homo sapiens]
Length = 657
Score = 1332 bits (3448), Expect = 0.0
Identities = 657/657 (100%), Positives = 657/657 (100%)
Query: 1 MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPGSENEKKCTLDQAFRGILE 60
MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPGSENEKKCTLDQAFRGILE
Sbjct: 1 MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPGSENEKKCTLDQAFRGILE 60
Query: 61 EEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNV 120
EEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNV
Sbjct: 61 EEIINHSSCENVLAIISLAIGGVTEGICTASTPFVLLGDVLDCLPLDQCDTIFTFVEKNV 120
Query: 121 ATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQ 180
ATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQ
Sbjct: 121 ATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQ 180
Query: 181 FNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCSIPIDYNLYRKFWS 240
FNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCSIPIDYNLYRKFWS
Sbjct: 181 FNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCSIPIDYNLYRKFWS 240
Query: 241 LQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAK 300
LQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAK
Sbjct: 241 LQDYFRNPVQCYEKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAK 300
Query: 301 FLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSV 360
FLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSV
Sbjct: 301 FLTSEKLMDLQLSDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSV 360
Query: 361 YQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDTKPTRIIRKRTAPE 420
YQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDTKPTRIIRKRTAPE
Sbjct: 361 YQLLSENPPDGERFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDTKPTRIIRKRTAPE 420
Query: 421 DFLGKGPTKKILMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMV 480
DFLGKGPTKKILMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMV
Sbjct: 421 DFLGKGPTKKILMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMV 480
Query: 481 ENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEI 540
ENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEI
Sbjct: 481 ENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEI 540
Query: 541 KTGEDEDEEDNDALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIR 600
KTGEDEDEEDNDALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIR
Sbjct: 541 KTGEDEDEEDNDALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIR 600
Query: 601 QIECDSEDMKMRAKQLLVAWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETNS 657
QIECDSEDMKMRAKQLLVAWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETNS
Sbjct: 601 QIECDSEDMKMRAKQLLVAWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETNS 657
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 6/140 (4%)
Query: 516 KSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGEQIE 575
KS + + L LP ++E ++ + E EE+ D ++N + R + E++
Sbjct: 1426 KSTRGLVHQAICNLNITLPIYTKESES-DQEQEEEIDMTSEKNPQDEQERIE----ERLA 1480
Query: 576 VFANKLGEQWKILAPYLEMKDSEIRQIECDSED-MKMRAKQLLVAWQDQEGVHATPENLI 634
A+ LG W LA L+ + +I QI ++ + ++ ++ LL W +++G HAT NL+
Sbjct: 1481 YIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLV 1540
Query: 635 NALNKSGLSDLAESLTNDNE 654
L K D+ + + E
Sbjct: 1541 ECLTKINRMDIVHLMETNTE 1560
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 6/140 (4%)
Query: 516 KSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGEQIE 575
KS + + L LP ++E ++ + E EE+ D ++N + R + E++
Sbjct: 1435 KSTRGLVHQAICNLNITLPIYTKESES-DQEQEEEIDMTSEKNPQDEQERIE----ERLA 1489
Query: 576 VFANKLGEQWKILAPYLEMKDSEIRQIECDSED-MKMRAKQLLVAWQDQEGVHATPENLI 634
A+ LG W LA L+ + +I QI ++ + ++ ++ LL W +++G HAT NL+
Sbjct: 1490 YIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLV 1549
Query: 635 NALNKSGLSDLAESLTNDNE 654
L K D+ + + E
Sbjct: 1550 ECLTKINRMDIVHLMETNTE 1569
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 47.8 bits (112), Expect = 3e-05
Identities = 36/156 (23%), Positives = 70/156 (44%), Gaps = 14/156 (8%)
Query: 513 QQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDE------EDNDALLKE-------NE 559
Q+ S E + + + + LPP E ED + E + L++ +
Sbjct: 3499 QEIVSDDESSSALEVSVIENLPPVETEHSVPEDIFDTRPIWDESIETLIERIPDENGHDH 3558
Query: 560 SPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSED-MKMRAKQLLV 618
+ D + ++ E++ A+ LG W LA L+ + +I QI ++ + ++ ++ LL
Sbjct: 3559 AEDPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLK 3618
Query: 619 AWQDQEGVHATPENLINALNKSGLSDLAESLTNDNE 654
W +++G HAT NL+ L K D+ + + E
Sbjct: 3619 YWLERDGKHATDTNLVECLTKINRMDIVHLMETNTE 3654
>gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinase 1
[Homo sapiens]
Length = 671
Score = 39.3 bits (90), Expect = 0.012
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 569 VTGEQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSE--DMKMRAKQLLVAWQDQEGV 626
+T + ++ LG+ WK A L S+I +I+ D E +K + Q+L W +EG+
Sbjct: 582 LTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGI 641
Query: 627 H-ATPENLINALNKSGLSDLAESL 649
AT L AL++ DL SL
Sbjct: 642 KGATVGKLAQALHQCSRIDLLSSL 665
>gi|13378137 TNFRSF1A-associated via death domain [Homo sapiens]
Length = 312
Score = 38.5 bits (88), Expect = 0.020
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 7/98 (7%)
Query: 566 DKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDS-------EDMKMRAKQLLV 618
++P++ + + FA +G +W+ + L+ +R DS E + +A QLL
Sbjct: 211 NRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLR 270
Query: 619 AWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETN 656
+ EG AT + L+ AL ++ L+ LAE L + N
Sbjct: 271 RFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPN 308
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 37.0 bits (84), Expect = 0.058
Identities = 77/432 (17%), Positives = 154/432 (35%), Gaps = 63/432 (14%)
Query: 193 EQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCSIPIDYNLYRKFWSLQDYFRNPVQCY 252
+QE GQ+ R+E M +E +M ++E + +K W ++ Q
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR-------DQEQKMWDQEERMEKKTQEQ 574
Query: 253 EKISWKTFLKYSEEVLAVFKSYKLDDTQASRKKMEELKTGGEHVYFAKFLTSEKLMDLQL 312
EK +W K EE + K+ + + ++ EE K E+ M Q
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEE-----------KMQEQEEKMQEQ- 622
Query: 313 SDSNFRRHILLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGE 372
+ + + +Q + + E+ +W ++ Q L E
Sbjct: 623 EEKMWEQEEKMQ--------------EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 373 RFSKMVEHILNTEENWNSWKNEGCPSFVKERTSDTKPTRIIRKRTAPEDFLGKGPTKKIL 432
KM E E+ W+ E +E+ T +R+ + + +K +
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRE------REKKM 722
Query: 433 MGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMVENEYKAVNNSNY 492
EE+ R E E M EE +E E M E E K
Sbjct: 723 REEEEMMR--------------EQEEKMQEQEEKMQE-----QEEEMWEQEEKMWEQEEK 763
Query: 493 GWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDND 552
W RL ++ + Q+ + + E E M + +E EE G++E +
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKM--RDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 553 ALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMR 612
+ E +++ + G++ +++ + + K+ +M++ E + ++ KMR
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKM---RGQEEKMR 878
Query: 613 AKQLLVAWQDQE 624
++ + Q+++
Sbjct: 879 EQEEKMRGQEEK 890
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 35.0 bits (79), Expect = 0.22
Identities = 36/165 (21%), Positives = 67/165 (40%), Gaps = 26/165 (15%)
Query: 492 YGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDN 551
Y + L +L + P FQ + Q+FK E +N+ + LP + ++K+ E ++ + N
Sbjct: 24 YDVKTLEVL--KGPVSFQKS-QRFKQQKESKQNLNVDKDTTLPASARKVKSSESKESQKN 80
Query: 552 DALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKM 611
D +D + ++I V + G Q D I+ +E + E M+
Sbjct: 81 D------------KDLKILEKEIRVLLQERGAQ-----------DRRIQDLETELEKMEA 117
Query: 612 RAKQLLVAWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETN 656
R L +AT E + L ++ ++ N N+ N
Sbjct: 118 RLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKN 162
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 34.7 bits (78), Expect = 0.29
Identities = 38/179 (21%), Positives = 74/179 (41%), Gaps = 11/179 (6%)
Query: 392 KNEGCPSFVKERTSDTKPTRIIRKRTAPEDFLGKGPTKKILMGN--EELTRLWNLCPDNM 449
K E C S K+ + T+ I+ +T + G+ KK+LM +E W +
Sbjct: 574 KTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALI 633
Query: 450 EACKSETREHMPTLEEFFEEAIEQADPE--------NMVENEYKAVNNSNYGWRALRLLA 501
E K+ E LE EE +Q + E +++ + + +N R L
Sbjct: 634 EQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGE 693
Query: 502 RRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENES 560
P + Q K + E E ++ +E ++K +++++++ + + KEN+S
Sbjct: 694 AADPVTGEKLKQIQKEIQEQ-ETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQS 751
Score = 30.8 bits (68), Expect = 4.1
Identities = 33/162 (20%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 484 YKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEE---- 539
+K V + WR + L + F +++ K L LE + + KEL +++
Sbjct: 616 FKRVQEAEDKWRGAQALIEQIKATF---SEKEKELENKLEELKKQQEKELFKLNQDNYIL 672
Query: 540 -IKTGEDEDEEDNDALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSE 598
K E+ L E+ D PVTGE+++ ++ EQ +L Y + +
Sbjct: 673 QAKLSSFEETNKKQRWLHFGEAAD-----PVTGEKLKQIQKEIQEQETLLQGYQQENERL 727
Query: 599 IRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLINALNKS 640
Q++ E K +++ +++ + + + +L ++KS
Sbjct: 728 YNQVKDLQEQNKKNEERM---FKENQSLFSEVASLKEQMHKS 766
>gi|34304368 dystrobrevin binding protein 1 isoform b [Homo sapiens]
Length = 303
Score = 34.3 bits (77), Expect = 0.37
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 32/193 (16%)
Query: 432 LMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMVENEYKAVNNSN 491
L G EL R ++ +E K R+ + T F+ ++ + ++E E+
Sbjct: 138 LCGQCELERCKHMQSQQLENYKKNKRKELET----FKAELDAEHAQKVLEMEHT------ 187
Query: 492 YGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDN 551
+ ++L R+ FF+ QQ + +YL +++A+ P G E N
Sbjct: 188 ---QQMKLKERQK--FFEEAFQQ--DMEQYLSTGYLQIAERREP------IGSMSSMEVN 234
Query: 552 DALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKD----SEIRQIECDSE 607
+L++ + D+ E ++VF N GE+ +L+P L D +E Q C S
Sbjct: 235 VDMLEQMDLMDISDQ-----EALDVFLNSGGEENTVLSPALGRVDKLALAEPGQYRCHSP 289
Query: 608 DMKMRAKQLLVAW 620
R L V +
Sbjct: 290 PKVRRENHLPVTY 302
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 33.5 bits (75), Expect = 0.64
Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 516 KSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGEQ-I 574
K + YL + L PS E+ G +ED D L E ++ +D TGEQ
Sbjct: 134 KKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFL-ERRVLELEKDTAATGEQHS 192
Query: 575 EVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLI 634
+ L + A ++K+ E+R E E+ + R K+LL + ++ + ENL
Sbjct: 193 RLRQENLQLVHRANALEEQLKEQELRACEMVLEETR-RQKELLCKMEREKSIEI--ENLQ 249
Query: 635 NALNK 639
L +
Sbjct: 250 TRLQQ 254
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 33.5 bits (75), Expect = 0.64
Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 516 KSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENESPDVRRDKPVTGEQ-I 574
K + YL + L PS E+ G +ED D L E ++ +D TGEQ
Sbjct: 430 KKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFL-ERRVLELEKDTAATGEQHS 488
Query: 575 EVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGVHATPENLI 634
+ L + A ++K+ E+R E E+ + R K+LL + ++ + ENL
Sbjct: 489 RLRQENLQLVHRANALEEQLKEQELRACEMVLEETR-RQKELLCKMEREKSIEI--ENLQ 545
Query: 635 NALNK 639
L +
Sbjct: 546 TRLQQ 550
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 33.5 bits (75), Expect = 0.64
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 16/131 (12%)
Query: 447 DNMEACKSETR-EHMPTLEEFFEEAIEQADPENMVENEYKAVNNSNYG--WRALRLLARR 503
D+M+ S T + P L+ + A+ +A+ + ++ + + S Y W A+R R
Sbjct: 223 DDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS 282
Query: 504 SPHFFQPTNQQFKSLPEYLENMVIKLAKELPP-PSEEIKTGEDEDEEDNDALLKENESPD 562
PT+ S P+ E +E PP PS + E+E+EE+ + E E +
Sbjct: 283 EA---LPTDLPAPSAPDLTEPK-----EEQPPVPSSPTEEEEEEEEEEEE----EAEEEE 330
Query: 563 VRRDKPVTGEQ 573
D V GEQ
Sbjct: 331 EEEDSEVQGEQ 341
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 33.5 bits (75), Expect = 0.64
Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 16/130 (12%)
Query: 512 NQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEED----NDALLKENESPDVRRDK 567
N+Q++ L L+ ++ ++AKE +EEIK E++ E N+AL K+ E +
Sbjct: 568 NKQYQQLESRLDEILSRIAKE----TEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQE 623
Query: 568 ---PVTGE--QIEVFANKLGEQWKILAPYLEMKDSEIRQIEC---DSEDMKMRAKQLLVA 619
+ G+ Q + KL ++ + L L + E Q+E D+E+M+ +L A
Sbjct: 624 YLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESA 683
Query: 620 WQDQEGVHAT 629
Q+Q V+A+
Sbjct: 684 LQEQHEVNAS 693
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 32.7 bits (73), Expect = 1.1
Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 270 VFKSYKLDDTQASRKKMEELKTGGEHV---YFAKFLTS-EKLMDLQLSDSNFRRH----I 321
V + K + Q RK E T E + F +F S E ++D L D +F
Sbjct: 1168 VARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILD-NLEDMDFTAFGDDDE 1226
Query: 322 LLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHI 381
+ Q L+L ++ ++ +S+ D T V +L +N DG + S ++ H
Sbjct: 1227 IPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHN 1286
Query: 382 LNTEENWNSWKN 393
+TEE W++
Sbjct: 1287 NDTEEEERLWRD 1298
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 32.7 bits (73), Expect = 1.1
Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 270 VFKSYKLDDTQASRKKMEELKTGGEHV---YFAKFLTS-EKLMDLQLSDSNFRRH----I 321
V + K + Q RK E T E + F +F S E ++D L D +F
Sbjct: 1168 VARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILD-NLEDMDFTAFGDDDE 1226
Query: 322 LLQYLILFQYLKGQVKFKSSNYVLTDEQSLWIEDTTKSVYQLLSENPPDGERFSKMVEHI 381
+ Q L+L ++ ++ +S+ D T V +L +N DG + S ++ H
Sbjct: 1227 IPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHN 1286
Query: 382 LNTEENWNSWKN 393
+TEE W++
Sbjct: 1287 NDTEEEERLWRD 1298
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 32.3 bits (72), Expect = 1.4
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 21/201 (10%)
Query: 421 DFLGKGPTKKILMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMV 480
D L G + N+EL + +N + + C+ E E + EF EE ++ ++
Sbjct: 686 DCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSIS 745
Query: 481 ENEYKAVN----NSNYGWRALRLLARRSPHFFQP--TNQQFK------SLPEYLENMVIK 528
E+ + + N N W + + L + QP +++F+ SL Y + + K
Sbjct: 746 ESPLEGTSHCHINLNETWTSKKKLFQVE---IQPEEKHEEFRKLFELISLLNYTADQIRK 802
Query: 529 LAKELPPPSEEIKTGEDEDEEDNDALLK--ENESPDVRRDKPVTGEQIEVFANKLGEQWK 586
+EL EE TG + E +L NE D ++++ KL +++
Sbjct: 803 KNREL----EEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFN 858
Query: 587 ILAPYLEMKDSEIRQIECDSE 607
L E SE + D+E
Sbjct: 859 DLVAEKEAVSSECVNLAKDNE 879
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 32.3 bits (72), Expect = 1.4
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 21/201 (10%)
Query: 421 DFLGKGPTKKILMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMV 480
D L G + N+EL + +N + + C+ E E + EF EE ++ ++
Sbjct: 579 DCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSIS 638
Query: 481 ENEYKAVN----NSNYGWRALRLLARRSPHFFQP--TNQQFK------SLPEYLENMVIK 528
E+ + + N N W + + L + QP +++F+ SL Y + + K
Sbjct: 639 ESPLEGTSHCHINLNETWTSKKKLFQVE---IQPEEKHEEFRKLFELISLLNYTADQIRK 695
Query: 529 LAKELPPPSEEIKTGEDEDEEDNDALLK--ENESPDVRRDKPVTGEQIEVFANKLGEQWK 586
+EL EE TG + E +L NE D ++++ KL +++
Sbjct: 696 KNREL----EEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFN 751
Query: 587 ILAPYLEMKDSEIRQIECDSE 607
L E SE + D+E
Sbjct: 752 DLVAEKEAVSSECVNLAKDNE 772
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 32.3 bits (72), Expect = 1.4
Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 21/201 (10%)
Query: 421 DFLGKGPTKKILMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMV 480
D L G + N+EL + +N + + C+ E E + EF EE ++ ++
Sbjct: 686 DCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSIS 745
Query: 481 ENEYKAVN----NSNYGWRALRLLARRSPHFFQP--TNQQFK------SLPEYLENMVIK 528
E+ + + N N W + + L + QP +++F+ SL Y + + K
Sbjct: 746 ESPLEGTSHCHINLNETWTSKKKLFQVE---IQPEEKHEEFRKLFELISLLNYTADQIRK 802
Query: 529 LAKELPPPSEEIKTGEDEDEEDNDALLK--ENESPDVRRDKPVTGEQIEVFANKLGEQWK 586
+EL EE TG + E +L NE D ++++ KL +++
Sbjct: 803 KNREL----EEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFN 858
Query: 587 ILAPYLEMKDSEIRQIECDSE 607
L E SE + D+E
Sbjct: 859 DLVAEKEAVSSECVNLAKDNE 879
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 568 PVTGEQIEVFAN-KLGEQWKILAPYLEMKDSEIRQIECDSEDMKMRAKQLLVAWQDQEGV 626
P E++E N G+ W+ LA L + I E +RA LL +W Q+
Sbjct: 341 PAKREEVEKLLNGSAGDTWRHLAGELGYQPEHIDSFT--HEACPVRA--LLASWATQDS- 395
Query: 627 HATPENLINALNKSGLSDLAESLTNDNETNS 657
AT + L+ AL + +DL ESL +++ S
Sbjct: 396 -ATLDALLAALRRIQRADLVESLCSESTATS 425
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 447 DNMEACKSETR-EHMPTLEEFFEEAIEQADPENMVENEYKAVNNSNYG--WRALRLLARR 503
D+M+ S T + P L+ + A+ +A+ + ++ + + S Y W A+R R
Sbjct: 223 DDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS 282
Query: 504 SPHFFQPTNQQFKSLPEYLENMVIKLAKELPP-PSEEIKTGEDEDEEDNDALLKENESPD 562
PT+ S P+ E +E PP PS + E+E+EE+ + +E E D
Sbjct: 283 EA---LPTDLPAPSAPDLTEPK-----EEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEED 334
Query: 563 VRRDKP 568
P
Sbjct: 335 SEEAPP 340
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 32.3 bits (72), Expect = 1.4
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 573 QIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKM-RAKQLLVAWQDQEGVHATPE 631
++ V + LG W LA L+ +I +I ++ + + ++ LL W +EG +A E
Sbjct: 1447 KMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLWVIREGQNANME 1506
Query: 632 NLINALNKSGLSDLAESL 649
NL AL ++ L
Sbjct: 1507 NLYTALQSIDRGEIVNML 1524
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 32.3 bits (72), Expect = 1.4
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 573 QIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKM-RAKQLLVAWQDQEGVHATPE 631
++ V + LG W LA L+ +I +I ++ + + ++ LL W +EG +A E
Sbjct: 1406 KMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLWVIREGQNANME 1465
Query: 632 NLINALNKSGLSDLAESL 649
NL AL ++ L
Sbjct: 1466 NLYTALQSIDRGEIVNML 1483
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 32.3 bits (72), Expect = 1.4
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 573 QIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKM-RAKQLLVAWQDQEGVHATPE 631
++ V + LG W LA L+ +I +I ++ + + ++ LL W +EG +A E
Sbjct: 1406 KMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLWVIREGQNANME 1465
Query: 632 NLINALNKSGLSDLAESL 649
NL AL ++ L
Sbjct: 1466 NLYTALQSIDRGEIVNML 1483
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 32.3 bits (72), Expect = 1.4
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 573 QIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKM-RAKQLLVAWQDQEGVHATPE 631
++ V + LG W LA L+ +I +I ++ + + ++ LL W +EG +A E
Sbjct: 1406 KMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLWVIREGQNANME 1465
Query: 632 NLINALNKSGLSDLAESL 649
NL AL ++ L
Sbjct: 1466 NLYTALQSIDRGEIVNML 1483
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 32.3 bits (72), Expect = 1.4
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 573 QIEVFANKLGEQWKILAPYLEMKDSEIRQIECDSEDMKM-RAKQLLVAWQDQEGVHATPE 631
++ V + LG W LA L+ +I +I ++ + + ++ LL W +EG +A E
Sbjct: 1406 KMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLWVIREGQNANME 1465
Query: 632 NLINALNKSGLSDLAESL 649
NL AL ++ L
Sbjct: 1466 NLYTALQSIDRGEIVNML 1483
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 31.6 bits (70), Expect = 2.4
Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 17/98 (17%)
Query: 472 EQADPENMVENEYKAVNNSNYGWRALRLLAR-RSPHFFQPTNQQFKSLPEYL-------- 522
EQAD EN +ENE N ++ +A R L+ SP+ + F S+ E L
Sbjct: 1111 EQADKENNLENEKMVKNKPDFYTKAFRSLSEIHSPNI---QDSSFDSVREGLVPLSVSSG 1167
Query: 523 ENMVIK--LAKELPPPSEEIKTGEDEDEEDNDALLKEN 558
+N++IK A E P + +DE E+ N K N
Sbjct: 1168 KNVIIKENFALECSP---AFQVSDDEHEKMNKMKFKVN 1202
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 31.6 bits (70), Expect = 2.4
Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 17/98 (17%)
Query: 472 EQADPENMVENEYKAVNNSNYGWRALRLLAR-RSPHFFQPTNQQFKSLPEYL-------- 522
EQAD EN +ENE N ++ +A R L+ SP+ + F S+ E L
Sbjct: 1111 EQADKENNLENEKMVKNKPDFYTKAFRSLSEIHSPNI---QDSSFDSVREGLVPLSVSSG 1167
Query: 523 ENMVIK--LAKELPPPSEEIKTGEDEDEEDNDALLKEN 558
+N++IK A E P + +DE E+ N K N
Sbjct: 1168 KNVIIKENFALECSP---AFQVSDDEHEKMNKMKFKVN 1202
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 31.6 bits (70), Expect = 2.4
Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 17/98 (17%)
Query: 472 EQADPENMVENEYKAVNNSNYGWRALRLLAR-RSPHFFQPTNQQFKSLPEYL-------- 522
EQAD EN +ENE N ++ +A R L+ SP+ + F S+ E L
Sbjct: 1111 EQADKENNLENEKMVKNKPDFYTKAFRSLSEIHSPNI---QDSSFDSVREGLVPLSVSSG 1167
Query: 523 ENMVIK--LAKELPPPSEEIKTGEDEDEEDNDALLKEN 558
+N++IK A E P + +DE E+ N K N
Sbjct: 1168 KNVIIKENFALECSP---AFQVSDDEHEKMNKMKFKVN 1202
>gi|34304370 dystrobrevin binding protein 1 isoform c [Homo sapiens]
Length = 270
Score = 31.6 bits (70), Expect = 2.4
Identities = 37/166 (22%), Positives = 71/166 (42%), Gaps = 28/166 (16%)
Query: 432 LMGNEELTRLWNLCPDNMEACKSETREHMPTLEEFFEEAIEQADPENMVENEYKAVNNSN 491
L G EL R ++ +E K R+ + T F+ ++ + ++E E+
Sbjct: 57 LCGQCELERCKHMQSQQLENYKKNKRKELET----FKAELDAEHAQKVLEMEHT------ 106
Query: 492 YGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSEEIKTGEDEDEEDN 551
+ ++L R+ FF+ QQ + +YL +++A+ P G E N
Sbjct: 107 ---QQMKLKERQK--FFEEAFQQ--DMEQYLSTGYLQIAERREP------IGSMSSMEVN 153
Query: 552 DALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDS 597
+L++ + D+ E ++VF N GE+ +L+P L + S
Sbjct: 154 VDMLEQMDLMDISDQ-----EALDVFLNSGGEENTVLSPALGPESS 194
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,490,712
Number of Sequences: 37866
Number of extensions: 1244175
Number of successful extensions: 4148
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 4076
Number of HSP's gapped (non-prelim): 135
length of query: 657
length of database: 18,247,518
effective HSP length: 109
effective length of query: 548
effective length of database: 14,120,124
effective search space: 7737827952
effective search space used: 7737827952
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.