Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 154240744
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens]
(1335 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens] 2697 0.0
gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens] 2003 0.0
gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens] 2003 0.0
gi|149944548 neurobeachin-like 2 [Homo sapiens] 947 0.0
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho... 455 e-127
gi|62422577 neurobeachin [Homo sapiens] 388 e-107
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 382 e-106
gi|31543297 neutral sphingomyelinase (N-SMase) activation associ... 320 4e-87
gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc... 320 4e-87
gi|191252801 WDFY family member 4 [Homo sapiens] 315 1e-85
gi|54292123 lysosomal trafficking regulator [Homo sapiens] 305 1e-82
gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] 96 2e-19
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] 96 2e-19
gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens] 96 2e-19
gi|32189425 WD repeat domain 69 [Homo sapiens] 57 2e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 1e-05
gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens] 50 1e-05
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 49 2e-05
gi|89886480 zinedin isoform 2 [Homo sapiens] 49 3e-05
gi|89886477 zinedin isoform 1 [Homo sapiens] 49 3e-05
gi|157266266 WD repeat domain 86 [Homo sapiens] 49 3e-05
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 49 4e-05
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 49 4e-05
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 49 4e-05
gi|142976686 nuclear autoantigen isoform 1 [Homo sapiens] 48 7e-05
gi|142976675 nuclear autoantigen isoform 2 [Homo sapiens] 48 7e-05
gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [... 47 9e-05
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 47 2e-04
gi|16554629 WD repeat domain 5 [Homo sapiens] 46 2e-04
gi|16554627 WD repeat domain 5 [Homo sapiens] 46 2e-04
>gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens]
Length = 1335
Score = 2697 bits (6991), Expect = 0.0
Identities = 1335/1335 (100%), Positives = 1335/1335 (100%)
Query: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV
Sbjct: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH
Sbjct: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV
Sbjct: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
Query: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL
Sbjct: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
Query: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA
Sbjct: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
Query: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL
Sbjct: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
Query: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA
Sbjct: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
Query: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA
Sbjct: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
Query: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR
Sbjct: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL
Sbjct: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
Query: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR
Sbjct: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
Query: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR
Sbjct: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
Query: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE
Sbjct: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
Query: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA
Sbjct: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
Query: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK
Sbjct: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
Query: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL
Sbjct: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
Query: 961 DALTDEKERKALEGMINNFGQTPCQLLKITISMNYVIGTHGWLPYDRNISNYFTFIKDQT 1020
DALTDEKERKALEGMINNFGQTPCQLLKITISMNYVIGTHGWLPYDRNISNYFTFIKDQT
Sbjct: 961 DALTDEKERKALEGMINNFGQTPCQLLKITISMNYVIGTHGWLPYDRNISNYFTFIKDQT 1020
Query: 1021 VTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIR 1080
VTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIR
Sbjct: 1021 VTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIR 1080
Query: 1081 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG 1140
HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG
Sbjct: 1081 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG 1140
Query: 1141 ISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSST 1200
ISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSST
Sbjct: 1141 ISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSST 1200
Query: 1201 EEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNL 1260
EEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNL
Sbjct: 1201 EEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNL 1260
Query: 1261 SINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLS 1320
SINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLS
Sbjct: 1261 SINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLS 1320
Query: 1321 QISAGETEYNTQDSK 1335
QISAGETEYNTQDSK
Sbjct: 1321 QISAGETEYNTQDSK 1335
>gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens]
Length = 2694
Score = 2003 bits (5189), Expect = 0.0
Identities = 988/988 (100%), Positives = 988/988 (100%)
Query: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV
Sbjct: 1291 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 1350
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH
Sbjct: 1351 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 1410
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV
Sbjct: 1411 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 1470
Query: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL
Sbjct: 1471 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 1530
Query: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA
Sbjct: 1531 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 1590
Query: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL
Sbjct: 1591 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 1650
Query: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA
Sbjct: 1651 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 1710
Query: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA
Sbjct: 1711 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 1770
Query: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR
Sbjct: 1771 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 1830
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL
Sbjct: 1831 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 1890
Query: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR
Sbjct: 1891 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 1950
Query: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR
Sbjct: 1951 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 2010
Query: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE
Sbjct: 2011 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 2070
Query: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA
Sbjct: 2071 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 2130
Query: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK
Sbjct: 2131 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 2190
Query: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL
Sbjct: 2191 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 2250
Query: 961 DALTDEKERKALEGMINNFGQTPCQLLK 988
DALTDEKERKALEGMINNFGQTPCQLLK
Sbjct: 2251 DALTDEKERKALEGMINNFGQTPCQLLK 2278
Score = 699 bits (1804), Expect = 0.0
Identities = 348/349 (99%), Positives = 348/349 (99%)
Query: 987 LKITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV 1046
L ITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV
Sbjct: 2346 LLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV 2405
Query: 1047 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1106
VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC
Sbjct: 2406 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 2465
Query: 1107 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ
Sbjct: 2466 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 2525
Query: 1167 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1226
YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI
Sbjct: 2526 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 2585
Query: 1227 LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG 1286
LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG
Sbjct: 2586 LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG 2645
Query: 1287 LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 1335
LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK
Sbjct: 2646 LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 2694
>gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens]
Length = 1404
Score = 2003 bits (5189), Expect = 0.0
Identities = 988/988 (100%), Positives = 988/988 (100%)
Query: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV
Sbjct: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH
Sbjct: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV
Sbjct: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
Query: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL
Sbjct: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
Query: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA
Sbjct: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
Query: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL
Sbjct: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
Query: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA
Sbjct: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
Query: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA
Sbjct: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
Query: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR
Sbjct: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL
Sbjct: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
Query: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR
Sbjct: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
Query: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR
Sbjct: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
Query: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE
Sbjct: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
Query: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA
Sbjct: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
Query: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK
Sbjct: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
Query: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL
Sbjct: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
Query: 961 DALTDEKERKALEGMINNFGQTPCQLLK 988
DALTDEKERKALEGMINNFGQTPCQLLK
Sbjct: 961 DALTDEKERKALEGMINNFGQTPCQLLK 988
Score = 699 bits (1804), Expect = 0.0
Identities = 348/349 (99%), Positives = 348/349 (99%)
Query: 987 LKITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV 1046
L ITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV
Sbjct: 1056 LLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV 1115
Query: 1047 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1106
VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC
Sbjct: 1116 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1175
Query: 1107 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ
Sbjct: 1176 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1235
Query: 1167 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1226
YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI
Sbjct: 1236 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1295
Query: 1227 LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG 1286
LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG
Sbjct: 1296 LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG 1355
Query: 1287 LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 1335
LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK
Sbjct: 1356 LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 1404
>gi|149944548 neurobeachin-like 2 [Homo sapiens]
Length = 2754
Score = 947 bits (2448), Expect = 0.0
Identities = 512/998 (51%), Positives = 670/998 (67%), Gaps = 85/998 (8%)
Query: 73 FWHS-----NPSHLSLDLSGIDSCEMS----DSGSQVPDSLPSTPSPVESTKSFSV---- 119
F+H+ P L L+ S + S + SG+ P S P TPSP++ + F
Sbjct: 1345 FYHALSPFCTPFDLGLERSSVGSGNTAGGGGSSGTLTPASQPGTPSPLDGPRPFPAAPGR 1404
Query: 120 HSDRESSITND-------MGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDD 172
HS S++ D + D + Q+ EEEL LLT++L V +G+E SD+
Sbjct: 1405 HSSSLSNVLEDGSLPEPTISGDDTSNTSNPQQTSEEELCNLLTNVLFSVTWRGVEGSDEA 1464
Query: 173 TWIERGQVFSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTA--ENAF 230
W ERGQVFS L++ G S+ L+RP D IK +LL+ MLE A+++ +EA + + + A
Sbjct: 1465 AWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPVGVLASLTQQAL 1524
Query: 231 RLVLIIQDFLQSEGLVNSNMWTEKLLEDMMLLFDCLSV---CYSESPVWVKLSQIQIQLL 287
L+ ++QDFL +EG N +W+EKL E + L D L + + +++QI ++L+
Sbjct: 1525 WLLRLLQDFLCAEGHGNQELWSEKLFEGVCSLLDRLGAWPHLANGTADLREMAQIGLRLV 1584
Query: 288 LGFIGRGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQT------- 340
LG+I + Q+ A A +L+ LLQT V ++EACY+L KLE L + + +
Sbjct: 1585 LGYILLEDPQLHAQAYVRLHMLLQTAVPARREEACYVLSKLEAALGRVLNTSSLESATDE 1644
Query: 341 --------------EIYSFLIPLVRTLVSKIYELLFMNLHLPSLPFTNGSSSFFEDFQEY 386
E S+L+PLVRTL+ + YE L + LPSLP TNGS +FFEDFQ +
Sbjct: 1645 AGSPLAAAAAAAAAERCSWLVPLVRTLLDRAYEPLGLQWGLPSLPPTNGSPTFFEDFQAF 1704
Query: 387 CNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMALYWKDCYEALMVNMHKRDREGGESKL 446
C + EW+ +I+K + P M Q+E T+ H+ M+ +W CY+ LM + +R E +S+
Sbjct: 1705 CATPEWRHFIDKQVQPTMSQFEMDTYAKSHDLMSGFWNACYDMLMSSGQRRQWERAQSRR 1764
Query: 447 KFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRWKAIQLYLTCERGPWAKRKQNP 506
FQEL +EP R+AR E LRY +LKQ ++Q L W A+ L G WA R
Sbjct: 1765 AFQELVLEPAQRRARLEGLRYTAVLKQQATQHSMALLHWGALWRQLASPCGAWALRDTPI 1824
Query: 507 IHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDTLL-LEVVKQVKV 565
WKL++ E YSRMRLKLVPN++F H EASALRDNLG P+ + L L V K+ KV
Sbjct: 1825 PRWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEVPLTPTEEASLPLAVTKEAKV 1884
Query: 566 SD----MVEDKLDLPEEDITARVN--VDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEI 619
S + ED+L ED A + ++ E +Q+EKLVL +C+L+T++ V+PG LE+
Sbjct: 1885 STPPELLQEDQLG---EDELAELETPMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEV 1941
Query: 620 TTQHIYFYDGS---IEKEDGVGFDFKWPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLN 676
TTQ++YFYDGS +E E+G+G+DF+ P +Q+RE+HLRR+NLRRSALE+F +DQ+NYFLN
Sbjct: 1942 TTQNVYFYDGSTERVETEEGIGYDFRRPLAQLREVHLRRFNLRRSALELFFIDQANYFLN 2001
Query: 677 FK-------------------------KEVRNKIYSRLLSLHSPNS-YYGSRSPQELFKA 710
F +VRN++YS LL L P+ Y SRSPQE+ +A
Sbjct: 2002 FPCKVGTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPPSQGYLSSRSPQEMLRA 2061
Query: 711 SGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRD 770
SGLTQKWV REISNF+YL+Q+NT+AGRTYNDL+QYPVFPW+LQDY S LDL+NPAVFRD
Sbjct: 2062 SGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRD 2121
Query: 771 LSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHI 830
LSKPIGVVN K+A+ +REKYE+FEDP GTIDKFHYGTHYSN+AGVMHYLIRVEPFT+LH+
Sbjct: 2122 LSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHV 2181
Query: 831 QLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISK 890
QLQSGRFDC+DRQFHS+ A WQA +++P DVKELIPEFFYFP+FLENQN F+LG LQ++
Sbjct: 2182 QLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTN 2241
Query: 891 ELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFY 950
E V DV+LP WA S EDFI +HR+ALESEYVSAHLHEWIDLIFGYKQRGPAA EALNVFY
Sbjct: 2242 EKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFY 2301
Query: 951 YCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLK 988
YC+YEGAVDLD +TDE+ERKALEG+I+NFGQTPCQLLK
Sbjct: 2302 YCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLK 2339
Score = 361 bits (926), Expect = 3e-99
Identities = 183/353 (51%), Positives = 250/353 (70%), Gaps = 9/353 (2%)
Query: 987 LKITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV 1046
L +T+S + ++GTH WLPYDRNISNYF+F KD T+ + KTQR ++G + PG ++ +
Sbjct: 2407 LLVTVSASGLLGTHSWLPYDRNISNYFSFSKDPTMGSHKTQRLLSGPWVPGSGVSGQALA 2466
Query: 1047 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1106
V+ D KLLFS G+WD S++V +L +GK++S + H+D+VTCLA D CGI+LISGSRDTTC
Sbjct: 2467 VAPDGKLLFSGGHWDGSLRVTALPRGKLLSQLSCHLDVVTCLALDTCGIYLISGSRDTTC 2526
Query: 1107 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
M+W++ QGG+ VGLA KP Q+LYGH V V ISTELDMAVSGS DGTVIIHT+++GQ
Sbjct: 2527 MVWRLLHQGGLSVGLAPKPVQVLYGHGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQ 2586
Query: 1167 YMRTLRPPCESSLFLTIP----NLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYL 1222
++ LRP L T P +LA+ EG IVV SS E+ + +LHL+S+NGK
Sbjct: 2587 FVAALRP-----LGATFPGPIFHLALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLR 2641
Query: 1223 GSQILKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSH 1282
S L EQ + + + + ++ G+ Q L I L++L + PL M++ I V VTKE SH
Sbjct: 2642 ASLPLAEQPTALTVTEDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERSH 2701
Query: 1283 ILVGLEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 1335
+LVGLEDGKLIVV G+P+E+RS Q +RK W SS+R+SQ+S+GETEYN +++
Sbjct: 2702 VLVGLEDGKLIVVVAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPTEAR 2754
>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
containing [Homo sapiens]
Length = 2863
Score = 455 bits (1171), Expect = e-127
Identities = 346/1090 (31%), Positives = 533/1090 (48%), Gaps = 157/1090 (14%)
Query: 324 ILGKLEHVLSQSIKEQTEIYSFLIP-LVRTLV-SKIYELLFMNLHLPSLPFTNGSSSFFE 381
I +LEH L ++ EI+ P L RTL+ S ELL SL SSS E
Sbjct: 1796 ITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGT---SLVCMKSSSSVVE 1852
Query: 382 DFQEYCNSNEWQVYIEKYI-VPYMKQYE-----AHTFYDGHENMALYWKDCYEALMVNMH 435
C S EWQ I+K + +++ + T D +A EA +
Sbjct: 1853 LVMLLC-SQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVA------NEAEFILSR 1905
Query: 436 KRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRW--KAIQLYLT 493
+R E +F+ L + ++ R++ +++++ + T + K I + LT
Sbjct: 1906 QR-AEDIHRHAEFESLCAQ-YSADKREDEKMCDHLIRAAKYRDHVTATQLIQKIINI-LT 1962
Query: 494 CERGPWAKRK-QNPIH-WKLANVENYSRMRLKLVPNYNFKTHEEASA-----------LR 540
+ G W P+ W+L E+ R R + V N TH EA+ LR
Sbjct: 1963 DKHGAWGNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHVCIFKLR 2022
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLD---LPEEDITARVNVDEKEEQDQKEK 597
+N S+ + + +L + + ++ + + L E D +VDEK+ ++
Sbjct: 2023 EN-----SKATDEDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEKDLENLAGP 2077
Query: 598 LVLMEDCELITIIDVIPGRLEITTQHIYFY----DGSIEKEDGV------GFDFKWPHSQ 647
+ L +L+ V+ G L +T+ +YF D + +K D G KW ++
Sbjct: 2078 VSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTE 2137
Query: 648 IREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGS------ 701
IR I RRY L+ +ALEIF ++ NF K L + +G
Sbjct: 2138 IRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRI 2197
Query: 702 --RSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEE 759
SP++LFKAS +TQ+W +REISNF+YL+ +NT+AGR+YNDL QYPVFPW++ +Y SEE
Sbjct: 2198 SLASPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEE 2257
Query: 760 LDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYL 819
LDL P FRDLSKPIG +N K A E+YE++ED + KFHYGTHYS ++ V+ +L
Sbjct: 2258 LDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQ--VPKFHYGTHYSTASFVLAWL 2315
Query: 820 IRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQN 879
+R+EPFTT + LQ G+FD ADR F SI W+ + D+KELIPEF+Y PE N N
Sbjct: 2316 LRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFN 2375
Query: 880 QFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRG 939
+NLG + +V+DV LP WAK++E+F++ +R ALESE+VS LH+WIDLIFGYKQ+G
Sbjct: 2376 NYNLGVMD-DGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQG 2434
Query: 940 PAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFG------------------- 980
P AV ALNVFYY +YEGAV+L+++TD R+A+E I +FG
Sbjct: 2435 PEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQ 2494
Query: 981 -----------QTPCQLLK-----------------------ITISMNYVIGTHGWLPYD 1006
Q +LK IT++ N + + W
Sbjct: 2495 VSPLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKW---- 2550
Query: 1007 RNISNYFTFIKDQTVTNPKT------------QRSINGSFAPGLEITSKLFVVSHDAKLL 1054
N+ + ++DQ P +R I +++ S+ FV++ D + +
Sbjct: 2551 HNLPAHQGAVQDQPYQLPVEIDPLIASNTGMHRRQITDLLDQSIQVHSQCFVITSDNRYI 2610
Query: 1055 FSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLA--TDYCG--IHLISGSRDTTCMIW- 1109
G+WD S +V S G++I + H D+VTCLA Y G +++SGSRD T ++W
Sbjct: 2611 LVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWY 2670
Query: 1110 ---QITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
+ + G P + P IL GH EV + EL + +SGS++G +IH++ G
Sbjct: 2671 WNGKCSGIGDNPGSETAAPRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSM-NGD 2729
Query: 1167 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1226
+RTL P E+ L + + S EGH V++ + FS+NGK +
Sbjct: 2730 LLRTLEGP-ENCLKPKL--IQASREGHCVIF---------YENGLFCTFSVNGKLQATME 2777
Query: 1227 LKEQVSDICII--GEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHIL 1284
+ + I + G++++TG +G + +R + L I + ++ + I+
Sbjct: 2778 TDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCII 2837
Query: 1285 VGLEDGKLIV 1294
G+ G +++
Sbjct: 2838 SGMASGSIVL 2847
>gi|62422577 neurobeachin [Homo sapiens]
Length = 2946
Score = 388 bits (996), Expect = e-107
Identities = 265/704 (37%), Positives = 373/704 (52%), Gaps = 55/704 (7%)
Query: 316 ENQDEACYILGKLEHVLSQSIKEQTEIYSFLIP-LVRTLV-SKIYELLFMNLHLPSLPFT 373
E+ E I KLE L + EI+ P L RTL+ S ELL + L
Sbjct: 1876 EDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELL-----IEGLVCM 1930
Query: 374 NGSSSFFEDFQEYCNSNEWQVYIEKYI-VPYMKQYE-----AHTFYDGHENMALYWKDCY 427
S+S E C S EWQ I+K + +++ H D +A
Sbjct: 1931 KSSTSVVELVMLLC-SQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVA------N 1983
Query: 428 EALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRWKA 487
EA + ++++ E +F+ + + R+E ++++ + T + K
Sbjct: 1984 EAEFI-LNRQRAEDVHKHAEFESQCAQ-YAADRREEEKMCDHLISAAKHRDHVTANQLKQ 2041
Query: 488 -IQLYLTCERGPWAKRKQNPIH--WKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLG 544
I LT + G W + +H W+L E+ R R + V N TH EA
Sbjct: 2042 KILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALL---KAA 2098
Query: 545 IQHSQPSSDTLLLEVVK-QVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVLMED 603
I++ + + Q V+ E +L L +D + + EKE + +VL
Sbjct: 2099 IEYGTEEDVVKSKKTFRSQAIVNQNAETELMLEGDDDAVSL-LQEKEIDNLAGPVVLSTP 2157
Query: 604 CELITIIDVIPGRLEITTQHIYFY----DGSIEKEDGV------GFDFKWPHSQIREIHL 653
+LI + V G L ITT IYF D + +K D G KW S+IR +
Sbjct: 2158 AQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFS 2217
Query: 654 RRYNLRRSALEIFHVDQSNYFLNFKKE--VRNKIYSRLLSLHSPNSYYGS--------RS 703
RRY L+ +ALE+F ++++ NF + V+ +YS L + YG +
Sbjct: 2218 RRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYS--LPRVGVGTSYGLPQARRISLAT 2275
Query: 704 PQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLN 763
P++L+K+S +TQ+W REISNF+YL+ +NT+AGRTYNDL QYPVFPW+L +Y SEELDL
Sbjct: 2276 PRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLT 2335
Query: 764 NPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVE 823
P FRDLSKPIG +N K A E+YE +ED +HY THYS + + +L+R+E
Sbjct: 2336 LPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSP--PYHYNTHYSTATSTLSWLVRIE 2393
Query: 824 PFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNL 883
PFTT + G+FD DR F S+ +W+ + DVKELIPEF+Y PE N N +NL
Sbjct: 2394 PFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNL 2453
Query: 884 GRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAV 943
G ++ + +VNDV LP WAK EDF+ +R ALESE+VS LH+WIDLIFGYKQRGP AV
Sbjct: 2454 G-VREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAV 2512
Query: 944 EALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLL 987
ALNVF+Y +YEG+V+LD++TD R+A+E I NFGQTP QLL
Sbjct: 2513 RALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLL 2556
Score = 113 bits (282), Expect = 1e-24
Identities = 80/282 (28%), Positives = 135/282 (47%), Gaps = 26/282 (9%)
Query: 984 CQLLKITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPK--TQRSINGSFAPGLEIT 1041
C L + +G G Y + +++ D + N +R I ++I
Sbjct: 2620 CSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQIN 2679
Query: 1042 SKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLA--TDYCG--IHL 1097
+ FVV+ D + + G+WD S +V S GK+ + H D+VTCLA Y G ++
Sbjct: 2680 AHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYI 2739
Query: 1098 ISGSRDTTCMIWQITQQ----GGVPVGL-ASKPFQILYGHTNEVLSVGISTELDMAVSGS 1152
+SGSRD T ++W + + G P P +L GH +EV+ V + EL + +SG+
Sbjct: 2740 VSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGA 2799
Query: 1153 RDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNAL 1212
++G ++HTI G +R L P E+ LF + +++S EGH ++Y ++
Sbjct: 2800 KEGPCLVHTI-TGDLLRALEGP-ENCLFPRL--ISVSSEGHCIIY---------YERGRF 2846
Query: 1213 HLFSINGKYLGSQILKEQVSDICII--GEHIVTGSIQGFLSI 1252
FSINGK L + + I + G+++VTG G + +
Sbjct: 2847 SNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEV 2888
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 382 bits (982), Expect = e-106
Identities = 264/729 (36%), Positives = 364/729 (49%), Gaps = 107/729 (14%)
Query: 570 EDKLDLPEEDITARVNVDEKEEQDQKEKLVLMED---------CELITIIDVIPGRLEIT 620
E+ + ++ I +++E+E+ D L L+E+ C + +D G L
Sbjct: 2499 EENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFG 2558
Query: 621 TQHIYFYDGSIEKEDGVGFDFK----------------------------WPHSQIREIH 652
+H Y DG D + + + I+E+H
Sbjct: 2559 KEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVH 2618
Query: 653 LRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKIYSRLLSL-----HSPNSYYGSRSPQEL 707
RRY L+ A+E+F D NY L F+K +RNK+Y R L++ S S G R +
Sbjct: 2619 KRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSV 2678
Query: 708 FKASGL----------TQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTS 757
+ SGL TQ+W EISNF YL+ +NT+AGR+YNDL QYPVFPWIL DY S
Sbjct: 2679 EQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDS 2738
Query: 758 EELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMH 817
EE+DL NP FR+L+KP+G ++ +++Y+++EDP G +HYGTHYS++ V
Sbjct: 2739 EEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVAS 2798
Query: 818 YLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATW-QALMDNPYDVKELIPEFFYFPEFLE 876
YL+R+EPFT + ++LQ G FD ADR FHS+ W A N DVKELIPEFFY PEFL
Sbjct: 2799 YLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLF 2858
Query: 877 NQNQFNLGRLQISKELVNDVILPKWAK-SAEDFIYKHRKALESEYVSAHLHEWIDLIFGY 935
N N F+LG Q +L DVILP WAK +FI HR+ALE +YVSAHLHEWIDLIFGY
Sbjct: 2859 NSNNFDLGCKQNGTKL-GDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGY 2917
Query: 936 KQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLK------- 988
KQ+GPAAVEA+NVF++ YEG VD+ + D + A G INNFGQ P QL K
Sbjct: 2918 KQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKR 2977
Query: 989 ITISMNYVIGTHGWLPYDRNISNYFTFIKD--QTVTNPKTQRSINGSFAPGLEITSKLFV 1046
+ +N LP + +F + + ++T K + G + T K +
Sbjct: 2978 VRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQ----IVCTDKGIL 3033
Query: 1047 VSHDAKLL--------FSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLA---TDYCGI 1095
K+L F+ GY D S ++ + K M + CL+ C I
Sbjct: 3034 AVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKA-------MTVYECLSEWGQILCAI 3086
Query: 1096 -----HLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVS 1150
+I+G T +W++ + K Q L GHT+ V S + VS
Sbjct: 3087 CPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLK--QALLGHTDTVTCATASLAYHIIVS 3144
Query: 1151 GSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKN 1210
GSRD T II + K ++ LR L I L G IV + T
Sbjct: 3145 GSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELT----GDIVSCAGT---------- 3190
Query: 1211 ALHLFSING 1219
+H++SING
Sbjct: 3191 YIHVWSING 3199
>gi|31543297 neutral sphingomyelinase (N-SMase) activation associated
factor isoform 1 [Homo sapiens]
Length = 917
Score = 320 bits (821), Expect = 4e-87
Identities = 246/777 (31%), Positives = 380/777 (48%), Gaps = 108/777 (13%)
Query: 582 ARVNVDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDF 641
AR + D+ Q+ EKL + E++T + PG + IT ++YF + + V
Sbjct: 178 ARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITL 237
Query: 642 KWPHSQIREIHLRRYNLRRSALEIFHVDQ---SNYFLNF-KKEVRNKIYSRLLSLHSPNS 697
+ +R I+ RR+ L LE+F + S+ +L F + + R+ +Y + +
Sbjct: 238 Q----DVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIAT------ 287
Query: 698 YYGSRSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTS 757
Y E S + Q W +SN+ YL+ +N +A R+ NDL+QYPVFPWI+ DY+S
Sbjct: 288 -YLEHHVAEHTAESYMLQ-WQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSS 345
Query: 758 EELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMH 817
ELDL+NP FRDLSKP+G +N++ + + +Y+ +P KF YG+HYS+ V+
Sbjct: 346 SELDLSNPGTFRDLSKPVGALNKERLERLLTRYQEMPEP-----KFMYGSHYSSPGYVLF 400
Query: 818 YLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFP-EFLE 876
YL+R+ P L LQ+GRFD ADR F+SI TW+ +D D KELIPEF+ FL
Sbjct: 401 YLVRIAPEYMLC--LQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYGDDVSFLV 458
Query: 877 NQNQFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYK 936
N + +LG+ Q ++V+DV LP WA S EDF+ K + ALES YVS HLHEWIDLIFGYK
Sbjct: 459 NSLKLDLGKRQ-GGQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYK 517
Query: 937 QRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQL---------- 986
Q+G AV A NVF+ +YEG VDL+++ D E+ A+ I FGQTP QL
Sbjct: 518 QKGSDAVGAHNVFHPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRIT 577
Query: 987 -----LKITISMNYVIG----------------THGW---------------------LP 1004
L T S N + T W +
Sbjct: 578 PKFKSLSQTSSYNASMADSPGEESFEDLTEESKTLAWNNITKLQLHEHYKIHKEAVTGIT 637
Query: 1005 YDRNISNYFTFIKDQTVTN-PKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNS 1063
RN S+ FT +D T+ K + + S + S ++ DA ++ S+ WDN+
Sbjct: 638 VSRNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDATVITSS--WDNN 695
Query: 1064 IQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPV---G 1120
+ S+ G+ ++ H D V+ + + L S S D+T +W GVP G
Sbjct: 696 VYFYSIAFGRRQDTLMGHDDAVSKIC--WHDNRLYSASWDSTVKVW-----SGVPAEMPG 748
Query: 1121 LASKPFQIL--YGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESS 1178
F +L H V ++ ++ + VSG+++GTV I + M + PC S
Sbjct: 749 TKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQI--PCHSG 806
Query: 1179 LFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICII- 1237
+ + + A S + V+ + T+ L++ + L S + ++ C +
Sbjct: 807 I---VCDTAFSPDSRHVLSTGTD--------GCLNVIDVQTGMLISSMTSDE-PQRCFVW 854
Query: 1238 -GEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLI 1293
G +++GS G L + DL +S + C+ + ++ S I+ G ED ++I
Sbjct: 855 DGNSVLSGSQSGELLVWDLLGAKISERIQGHTGAVTCIWMNEQCSSIITGGEDRQII 911
>gi|221625547 neutral sphingomyelinase (N-SMase) activation associated
factor isoform 2 [Homo sapiens]
Length = 948
Score = 320 bits (821), Expect = 4e-87
Identities = 246/777 (31%), Positives = 380/777 (48%), Gaps = 108/777 (13%)
Query: 582 ARVNVDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDF 641
AR + D+ Q+ EKL + E++T + PG + IT ++YF + + V
Sbjct: 209 ARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITL 268
Query: 642 KWPHSQIREIHLRRYNLRRSALEIFHVDQ---SNYFLNF-KKEVRNKIYSRLLSLHSPNS 697
+ +R I+ RR+ L LE+F + S+ +L F + + R+ +Y + +
Sbjct: 269 Q----DVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIAT------ 318
Query: 698 YYGSRSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTS 757
Y E S + Q W +SN+ YL+ +N +A R+ NDL+QYPVFPWI+ DY+S
Sbjct: 319 -YLEHHVAEHTAESYMLQ-WQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSS 376
Query: 758 EELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMH 817
ELDL+NP FRDLSKP+G +N++ + + +Y+ +P KF YG+HYS+ V+
Sbjct: 377 SELDLSNPGTFRDLSKPVGALNKERLERLLTRYQEMPEP-----KFMYGSHYSSPGYVLF 431
Query: 818 YLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFP-EFLE 876
YL+R+ P L LQ+GRFD ADR F+SI TW+ +D D KELIPEF+ FL
Sbjct: 432 YLVRIAPEYMLC--LQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYGDDVSFLV 489
Query: 877 NQNQFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYK 936
N + +LG+ Q ++V+DV LP WA S EDF+ K + ALES YVS HLHEWIDLIFGYK
Sbjct: 490 NSLKLDLGKRQ-GGQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYK 548
Query: 937 QRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQL---------- 986
Q+G AV A NVF+ +YEG VDL+++ D E+ A+ I FGQTP QL
Sbjct: 549 QKGSDAVGAHNVFHPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRIT 608
Query: 987 -----LKITISMNYVIG----------------THGW---------------------LP 1004
L T S N + T W +
Sbjct: 609 PKFKSLSQTSSYNASMADSPGEESFEDLTEESKTLAWNNITKLQLHEHYKIHKEAVTGIT 668
Query: 1005 YDRNISNYFTFIKDQTVTN-PKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNS 1063
RN S+ FT +D T+ K + + S + S ++ DA ++ S+ WDN+
Sbjct: 669 VSRNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDATVITSS--WDNN 726
Query: 1064 IQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPV---G 1120
+ S+ G+ ++ H D V+ + + L S S D+T +W GVP G
Sbjct: 727 VYFYSIAFGRRQDTLMGHDDAVSKIC--WHDNRLYSASWDSTVKVW-----SGVPAEMPG 779
Query: 1121 LASKPFQIL--YGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESS 1178
F +L H V ++ ++ + VSG+++GTV I + M + PC S
Sbjct: 780 TKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQI--PCHSG 837
Query: 1179 LFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICII- 1237
+ + + A S + V+ + T+ L++ + L S + ++ C +
Sbjct: 838 I---VCDTAFSPDSRHVLSTGTD--------GCLNVIDVQTGMLISSMTSDE-PQRCFVW 885
Query: 1238 -GEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLI 1293
G +++GS G L + DL +S + C+ + ++ S I+ G ED ++I
Sbjct: 886 DGNSVLSGSQSGELLVWDLLGAKISERIQGHTGAVTCIWMNEQCSSIITGGEDRQII 942
>gi|191252801 WDFY family member 4 [Homo sapiens]
Length = 3184
Score = 315 bits (808), Expect = 1e-85
Identities = 275/936 (29%), Positives = 420/936 (44%), Gaps = 106/936 (11%)
Query: 416 HENMALYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLR-YNNMLKQL 474
H + W + M M R + E K + +E + R+ ++ Y + +++
Sbjct: 2190 HHSKVTLWSGSLSSAMKLMPGRQAKDPECKTEDFVSCIENYRRRGQELYASLYKDHVQRR 2249
Query: 475 SSQQLATLRRWKAIQLYLTCERGPWAKRKQNP--IHWKLANVENYSRMRLKL-----VPN 527
+ W IQ L E G W++ ++ W+L E +RMR ++ +
Sbjct: 2250 KCGNIKAANAWARIQEQLFGELGLWSQGEETKPCSPWELDWREGPARMRKRIKRLSPLEA 2309
Query: 528 YNFKTHEEASALRDNLGIQHSQPSSDTLLLEVVKQ----------------VKVSDMVED 571
+ H+E+ D++ +++ + L E + + S ED
Sbjct: 2310 LSSGRHKESQDKNDHISQTNAENQDELTLREAEGEPDEVGVDCTQLTFFPALHESLHSED 2369
Query: 572 KLDLPEEDITARVNVDEKEEQDQKEKLVLMED-----------------CELITII---D 611
L+L E + +KE+ QK LV+++ CE T+ D
Sbjct: 2370 FLELCRERQVILQELLDKEKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGD 2429
Query: 612 VIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHS--QIREIHLRRYNLRRSALEIFHVD 669
V R ++ F K+ HS +RE+ R+ L+ ALEIF +
Sbjct: 2430 VYCTRHCLSNISDPFIFNLCSKDRSTDHYSCQCHSYADMRELRQARFLLQDIALEIFFHN 2489
Query: 670 QSNYFLNFKKEVRNKIYSRLLSLH-SPNSYYGSRSPQELFKASG----LTQKWVNREISN 724
+ FL F R+K + S S S L + G + QKW R+ISN
Sbjct: 2490 GYSKFLVFYNNDRSKAFKSFCSFQPSLKGKATSEDTLSLRRYPGSDRIMLQKWQKRDISN 2549
Query: 725 FDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNEKNAK 784
F+YL+ +NT AGRT ND QYPVFPW+L DYTSE L+L NP +FRDLSKP+G ++
Sbjct: 2550 FEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRDLSKPMGAQTKERKL 2609
Query: 785 AMREKYENFEDPMGTID-KFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQ 843
++++ E G + + HY THYS++ V YL+R+ PFT LQ G FD ADR
Sbjct: 2610 KFIQRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCALQGGSFDVADRM 2669
Query: 844 FHSIPATWQ-ALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPKWA 902
FHS+ +TW+ A +N DV+EL PEFFY PEFL N N G +Q ++ DV LP WA
Sbjct: 2670 FHSVKSTWESASRENMSDVRELTPEFFYLPEFLTNCNGVEFGCMQ-DGTVLGDVQLPPWA 2728
Query: 903 KS-AEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLD 961
FI HRKALES++VSA+LH WIDLIFGYKQ+GPAAV+A+N+F+ Y +DL
Sbjct: 2729 DGDPRKFISLHRKALESDFVSANLHHWIDLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLS 2788
Query: 962 ALTDEKERKALEGMINNFGQTPCQLLKITISMNYVIG---------THGWLP-YDRNISN 1011
++TD + + G ++NFGQ P QL G T LP + +
Sbjct: 2789 SITDPLIKSTILGFVSNFGQVPKQLFTKPHPARTAAGKPLPGKDVSTPVSLPGHPQPFFY 2848
Query: 1012 YFTFIKDQTVTNPKTQRSINGSFAPGLEI-----TSKLFVVSHDAKLL--------FSAG 1058
++ VT GS +P I T K + K+L FS G
Sbjct: 2849 SLQSLRPSQVTVKDMYLFSLGSESPKGAIGHIVSTEKTILAVERNKVLLPPLWNRTFSWG 2908
Query: 1059 YWDNSIQVMSLTKGKIISHIIRHMDIVTCL-ATDYCGIHLISGSRDTTCMIWQITQQGGV 1117
+ D S + S K++ CL A +++ T +W+++ G
Sbjct: 2909 FDDFSCCLGSYGSDKVLMTFENLAAWGRCLCAVCPSPTTIVTSGTSTVVCVWELSMTKGR 2968
Query: 1118 PVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCES 1177
P GL + Q LYGHT V + S + VSGS+D T I+ + ++ L E
Sbjct: 2969 PRGLRLR--QALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREG 3026
Query: 1178 SLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQIL----KEQVSD 1233
+TI +++ G IV + L L+++NG+ L S + ++
Sbjct: 3027 ISAITISDVS----GTIVSCAGAH----------LSLWNVNGQPLASITTAWGPEGAITC 3072
Query: 1234 ICII-------GEHIVTGSIQGFLSIRDLHSLNLSI 1262
C++ + I+TGS G + + + +S+
Sbjct: 3073 CCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSV 3108
>gi|54292123 lysosomal trafficking regulator [Homo sapiens]
Length = 3801
Score = 305 bits (782), Expect = 1e-82
Identities = 194/522 (37%), Positives = 282/522 (54%), Gaps = 38/522 (7%)
Query: 479 LATLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASA 538
L+ R W+ + LT +R W P W+L E +R R +L Y T
Sbjct: 2917 LSASRHWQELIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCY--LTIPNKYL 2974
Query: 539 LRDNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITAR-VNVDEKEEQDQKEK 597
LRD + + L E S V+DK + R ++V E +
Sbjct: 2975 LRDRQKSEDVVKPPLSYLFEDKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGE-- 3032
Query: 598 LVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYN 657
+L+ C + + D +E ++ G +E F W + +I+E+H R +
Sbjct: 3033 -LLLGKCGMYFVEDNASDTVESSS-----LQGELEPAS-----FSWTYEEIKEVHKRWWQ 3081
Query: 658 LRRSALEIFHVDQSNYFLNFKK-EVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQK 716
LR +A+EIF + L F +VR+ +Y +L+ + PN E + LT
Sbjct: 3082 LRDNAVEIFLTNGRTLLLAFDNTKVRDDVYHNILTNNLPNLL-------EYGNITALTNL 3134
Query: 717 WVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIG 776
W +I+NF+YL +N AGR++NDL QYPVFP+IL DY SE LDLN+ ++R+LSKPI
Sbjct: 3135 WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIA 3194
Query: 777 VVNEKNAKAMREKYENFE----------DPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFT 826
V ++ + Y+ E DPM + +HYG+HYSNS V+H+L+R+ PFT
Sbjct: 3195 VQYKEKEDRYVDTYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFT 3254
Query: 827 TLHIQLQSGRFDCADRQFHSIPATWQ-ALMDNPYDVKELIPEFFYFPEFLENQNQFNLGR 885
+ + Q FD DR FHS TW+ + ++ DVKELIPEFFY PEFL N+ F+ G
Sbjct: 3255 KMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGV 3314
Query: 886 LQISKELVNDVILPKWAKS-AEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVE 944
Q + E VN V LP WA++ FI HR+ALES+YVS ++ +WIDL+FGYKQ+G A+V+
Sbjct: 3315 RQ-NGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQ 3373
Query: 945 ALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQL 986
A+NVF+ +Y G +D+ A+ D +R+ALE MI +GQTP QL
Sbjct: 3374 AINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQL 3414
Score = 39.7 bits (91), Expect = 0.020
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 1054 LFSAGYWDNSIQVMSLTKGKIISHI--IRHMDIVTCL-ATDYCGIHLISGSRDTTCMIWQ 1110
+ S GY DN +++ S ++ I + + +C D C L +GS+ +
Sbjct: 3536 ILSWGYADNILRLKSKQSEPPVNFIQSSQQYQVTSCAWVPDSC--QLFTGSKCGVITAYT 3593
Query: 1111 ITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRT 1170
P + + LYGHT E+ S+ + + +S SRDGT II + + Y+++
Sbjct: 3594 NRFTSSTPSEIEMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQS 3653
Query: 1171 L 1171
L
Sbjct: 3654 L 3654
>gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 95.9 bits (237), Expect = 2e-19
Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 29/241 (12%)
Query: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
Query: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
K +N K K + YE G + H H S+ + Y + T
Sbjct: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
Query: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
Query: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
Query: 948 V 948
V
Sbjct: 564 V 564
Score = 31.2 bits (69), Expect = 7.0
Identities = 49/208 (23%), Positives = 75/208 (36%), Gaps = 25/208 (12%)
Query: 1059 YWDNSIQVMSLTKGKIISHIIR------HMDIVTCLATDYCGIHLISGSRDTTCMIWQIT 1112
YW I V S H IR H V C+A +SGS+D T +W +
Sbjct: 1620 YWQYEIGV-SQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLY 1678
Query: 1113 QQGGVPVGLASKPFQILY-GHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
G G + +++Y H V VG V S DG V + G+ +RT+
Sbjct: 1679 NYGD---GTSETAPRLVYTQHRKSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTV 1733
Query: 1172 RP-----PCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1226
P P + + P+ +I+ + ST + H F + G +
Sbjct: 1734 EPLDSRVPLTAVAVMPAPHTSIT----MASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLV 1789
Query: 1227 LKEQVSDICIIGEHIVTGSIQGFLSIRD 1254
+S G +V G GF+ + D
Sbjct: 1790 RALAISP---SGRSVVAGFSSGFMVLLD 1814
>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 2240
Score = 95.9 bits (237), Expect = 2e-19
Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 29/241 (12%)
Query: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 647 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 699
Query: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
K +N K K + YE G + H H S+ + Y + T
Sbjct: 700 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 758
Query: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 759 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 807
Query: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 808 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 862
Query: 948 V 948
V
Sbjct: 863 V 863
Score = 31.2 bits (69), Expect = 7.0
Identities = 49/208 (23%), Positives = 75/208 (36%), Gaps = 25/208 (12%)
Query: 1059 YWDNSIQVMSLTKGKIISHIIR------HMDIVTCLATDYCGIHLISGSRDTTCMIWQIT 1112
YW I V S H IR H V C+A +SGS+D T +W +
Sbjct: 1919 YWQYEIGV-SQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLY 1977
Query: 1113 QQGGVPVGLASKPFQILY-GHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
G G + +++Y H V VG V S DG V + G+ +RT+
Sbjct: 1978 NYGD---GTSETAPRLVYTQHRKSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTV 2032
Query: 1172 RP-----PCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1226
P P + + P+ +I+ + ST + H F + G +
Sbjct: 2033 EPLDSRVPLTAVAVMPAPHTSIT----MASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLV 2088
Query: 1227 LKEQVSDICIIGEHIVTGSIQGFLSIRD 1254
+S G +V G GF+ + D
Sbjct: 2089 RALAISP---SGRSVVAGFSSGFMVLLD 2113
>gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 95.9 bits (237), Expect = 2e-19
Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 29/241 (12%)
Query: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
Query: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
K +N K K + YE G + H H S+ + Y + T
Sbjct: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
Query: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
Query: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
Query: 948 V 948
V
Sbjct: 564 V 564
Score = 31.2 bits (69), Expect = 7.0
Identities = 49/208 (23%), Positives = 75/208 (36%), Gaps = 25/208 (12%)
Query: 1059 YWDNSIQVMSLTKGKIISHIIR------HMDIVTCLATDYCGIHLISGSRDTTCMIWQIT 1112
YW I V S H IR H V C+A +SGS+D T +W +
Sbjct: 1620 YWQYEIGV-SQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLY 1678
Query: 1113 QQGGVPVGLASKPFQILY-GHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
G G + +++Y H V VG V S DG V + G+ +RT+
Sbjct: 1679 NYGD---GTSETAPRLVYTQHRKSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTV 1733
Query: 1172 RP-----PCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1226
P P + + P+ +I+ + ST + H F + G +
Sbjct: 1734 EPLDSRVPLTAVAVMPAPHTSIT----MASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLV 1789
Query: 1227 LKEQVSDICIIGEHIVTGSIQGFLSIRD 1254
+S G +V G GF+ + D
Sbjct: 1790 RALAISP---SGRSVVAGFSSGFMVLLD 1814
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/196 (24%), Positives = 87/196 (44%), Gaps = 24/196 (12%)
Query: 1056 SAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQG 1115
+ G +D + ++ S+ GK H + CL+ + + +GS DTT +W I Q
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI--QN 208
Query: 1116 GVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPC 1175
G V L GH+ E++S+ +T D ++GS D TV++ G+ + L C
Sbjct: 209 GEEV-------YTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHC 261
Query: 1176 ESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI-LKEQVSDI 1234
I + + +W+ +++ S ++ L D + NGK + + +++ D
Sbjct: 262 AE-----ISSASFNWDCSLILTGSMDKTCKLWD-------ATNGKCVATLTGHDDEILDS 309
Query: 1235 CI--IGEHIVTGSIQG 1248
C G+ I T S G
Sbjct: 310 CFDYTGKLIATASADG 325
Score = 49.7 bits (117), Expect = 2e-05
Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1055 FSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLA-TDYCGIHLISGSRDTTCMIWQITQ 1113
F G +D + ++ G+ ++ + H ++V +A + G + +GS D TC +W +
Sbjct: 107 FITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVE- 165
Query: 1114 QGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLR 1172
K + GHT E++ + + + + +GS D T + IQ G+ + TLR
Sbjct: 166 --------TGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLR 216
Score = 48.5 bits (114), Expect = 4e-05
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 23/198 (11%)
Query: 1006 DRNISNYFTFIKDQTVT--NPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNS 1063
DR I+ F D TV + T R +N EI+S F + D L+ + G D +
Sbjct: 232 DRIITGSF----DHTVVVWDADTGRKVNILIGHCAEISSASF--NWDCSLILT-GSMDKT 284
Query: 1064 IQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLAS 1123
++ T GK ++ + H D + DY G + + S D T I+ +
Sbjct: 285 CKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATR--------- 335
Query: 1124 KPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTI 1183
K L GH E+ + + + + ++GS D T I Q GQ ++ L + I
Sbjct: 336 KCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDE-----I 390
Query: 1184 PNLAISWEGHIVVYSSTE 1201
+ A +++G+IV+ S +
Sbjct: 391 FSCAFNYKGNIVITGSKD 408
Score = 46.6 bits (109), Expect = 2e-04
Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 10/108 (9%)
Query: 1049 HDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMI 1108
+ KL+ +A D + ++ S K I+ + H ++ ++ + G HL++GS D T I
Sbjct: 313 YTGKLIATASA-DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARI 371
Query: 1109 WQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGT 1156
W Q G + Q+L GHT+E+ S + + ++ ++GS+D T
Sbjct: 372 WD-AQTG--------QCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNT 410
Score = 40.4 bits (93), Expect = 0.011
Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 1054 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQ 1113
L + G D + ++ + G+ + + H + L+ + G +I+GS D T ++W
Sbjct: 191 LVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD- 249
Query: 1114 QGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
+ IL GH E+ S + + + ++GS D T + G+ + TL
Sbjct: 250 --------TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATL 299
Score = 37.0 bits (84), Expect = 0.13
Identities = 40/176 (22%), Positives = 71/176 (40%), Gaps = 21/176 (11%)
Query: 1081 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG 1140
H+ +T +A + G I+GS D TC +W + + L GH N V ++
Sbjct: 91 HILPLTNVALNKSGSCFITGSYDRTCKLWDTA---------SGEELNTLEGHRNVVYAIA 141
Query: 1141 ISTEL-DMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSS 1199
+ D +GS D T + +++ G+ T R I L+ + + +V S
Sbjct: 142 FNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAE-----IVCLSFNPQSTLVATGS 196
Query: 1200 TEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLSIRD 1254
+ L D +N ++++ G L S G+ I+TGS + + D
Sbjct: 197 MDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTS-----GDRIITGSFDHTVVVWD 247
Score = 34.7 bits (78), Expect = 0.63
Identities = 16/53 (30%), Positives = 28/53 (52%)
Query: 1058 GYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQ 1110
G D + ++ G+ + + H D + A +Y G +I+GS+D TC IW+
Sbjct: 363 GSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/136 (29%), Positives = 57/136 (41%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N + +S+ S S D S DS SDS + S S S + S SD
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 123 RESSITNDMGFSDDFS 138
+SS +D S D S
Sbjct: 853 SDSSNRSDSSNSSDSS 868
Score = 46.6 bits (109), Expect = 2e-04
Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 1/136 (0%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D ++++ SSD + D S DS+ DSS
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 64 SFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S +S N + +S+ S S D S DS SDS + S S S S+ S +
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 983 SDSSDSSDSSDSSDSS 998
Score = 45.4 bits (106), Expect = 4e-04
Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 3/141 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S NS + +D + + ++ SSD S + DS+ DSS
Sbjct: 588 SDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS 647
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S+N + SN S+ S DS + SDS S S S S + + S SD
Sbjct: 648 SDSSDNSDSSDSSNSSNSS---DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S +D S D S S +
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSD 725
Score = 44.3 bits (103), Expect = 8e-04
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 2/143 (1%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + + D+ +SD S S+N S + S + +S DS+ +SS
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVHS 121
S S N + SN S S + DS + SDS S DS S+ S S S S +S
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 122 DRESSITNDMGFSDDFSLLESQE 144
S+ ++ SD +S +
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSD 1041
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/135 (32%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D S S+N S S + S DS+ DSS
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S N + +S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSS--DSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSS- 1067
Query: 124 ESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1068 DSSDSSDSSDSSDSS 1082
Score = 43.1 bits (100), Expect = 0.002
Identities = 36/141 (25%), Positives = 60/141 (42%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
++ + S D+K +S + + + S++ S+ S + S DS+ DSS
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + S+ S S D DS + S+S S DS S+ S S S S S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S+ ++ SD + +S +
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSD 769
Score = 43.1 bits (100), Expect = 0.002
Identities = 41/138 (29%), Positives = 58/138 (42%), Gaps = 2/138 (1%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S N + S+ S S D S DS + SDS + S S S + + S S
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 122 D-RESSITNDMGFSDDFS 138
D ESS ++D S D S
Sbjct: 1146 DSSESSDSSDSSDSSDSS 1163
Score = 43.1 bits (100), Expect = 0.002
Identities = 44/138 (31%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD E S S+N S S + S DS+ DSS
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS E SDS S DS S+ S S S S +
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSS--DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1180 SS-DSSDSSDSSDSSDSS 1196
Score = 42.0 bits (97), Expect = 0.004
Identities = 45/150 (30%), Positives = 67/150 (44%), Gaps = 10/150 (6%)
Query: 3 DNDKNMSTEDTKKNSDEK-------TDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFP 55
++D + ST DT NSD D +K S + SSD S + +S DS+
Sbjct: 511 EDDDSDSTSDTN-NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569
Query: 56 EDSSVGELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTK 115
+ S S + + S+ S S + DS + SDS S DS S+ S +S+K
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS-SDSSDSSDSSDSKSDSSK 628
Query: 116 SFSVHSDRES-SITNDMGFSDDFSLLESQE 144
S S SD +S S ++D SD +S +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Score = 41.6 bits (96), Expect = 0.005
Identities = 43/142 (30%), Positives = 58/142 (40%), Gaps = 11/142 (7%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD K+D K S + SSD S D S DSN+ DSS
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSK-----SESDSSDSDSKSD--SSDSNS----SDSSDNS 654
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N S+ S S D S S S DS S+ S S S S SD
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S ++ SD + +S +
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSD 736
Score = 41.2 bits (95), Expect = 0.007
Identities = 42/141 (29%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D + + ++ SSD S + +S DS+ DSS
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSDSSD 1074
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + E S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSS--DSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD ES +
Sbjct: 1132 SSDSSDSSNSSDSSDSSESSD 1152
Score = 41.2 bits (95), Expect = 0.007
Identities = 44/139 (31%), Positives = 59/139 (42%), Gaps = 4/139 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S+N S S E S DS+ DSS
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSV 119
S S + S+ S S D S DS + SDS S DS S+ S S S S
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 120 HSDRESSITNDMGFSDDFS 138
S+ ESS ++D S D S
Sbjct: 1230 DSN-ESSDSSDSSDSSDSS 1247
Score = 40.8 bits (94), Expect = 0.009
Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 2/136 (1%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ ++ ++ D +SD + S S+N S S + +S DS+ + S
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ + S+ S S DS + SDS S DS S+ S S S S S
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS-SNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1041 -DSSDSSDSSDSSDSS 1055
Score = 40.8 bits (94), Expect = 0.009
Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 3/142 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S +S + SDS S DS S+ S S S S S
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSS--ESSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSS 1115
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSD 1137
Score = 40.8 bits (94), Expect = 0.009
Identities = 36/145 (24%), Positives = 57/145 (39%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S + S S DS S+ S S S S +S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 123 RESSITNDMGFSDDFSLLESQERCE 147
S ++ SD + +S + E
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSE 1149
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/136 (30%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ ++ + D+ +SD + S S++ S S + +S DS+ DSS
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + E S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSS--DSSDSSDS-SDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1197 -DSSDSSDSSDSSDSS 1211
Score = 40.4 bits (93), Expect = 0.011
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 1/137 (0%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+D + S++ + NS + S S+N S S + +S DS+ +SS
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S + + +S+ S+ S + S DS SDS + S S S +S+ S +
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 122 DRESSITNDMGFSDDFS 138
+SS +++ S D S
Sbjct: 829 SSDSSDSSNSSDSSDSS 845
Score = 40.4 bits (93), Expect = 0.011
Identities = 40/145 (27%), Positives = 61/145 (42%), Gaps = 3/145 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S++ S S + +S DS+ DSS
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSV 119
S S + + +S+ S S D S DS SDS S+ DS S+ S S S S
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 120 HSDRESSITNDMGFSDDFSLLESQE 144
S S +N SD +S +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSD 1194
Score = 40.4 bits (93), Expect = 0.011
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ ++SD + S S++ S S + +S DS+ DSS
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS + SDS ++ DS S+ S S S S
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254
Query: 121 SDRESSITNDMGFSDD 136
S S T+D D
Sbjct: 1255 SSDSSDSTSDSNDESD 1270
Score = 40.0 bits (92), Expect = 0.015
Identities = 36/147 (24%), Positives = 56/147 (38%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + S+ D+ +SD + S S++ S S S SN+ DSS
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N + S+ S S D S S S DS S+ S S + S +S
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 123 RESSITNDMGFSDDFSLLESQERCEEE 149
S +N S+ +S + + +
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Score = 39.7 bits (91), Expect = 0.020
Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S NS + +D ++ + ++ SSD S E +S DS+ DS +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD--SNESSNSSDSSDSSNSSDSDSSDS 908
Query: 64 SFKSENQEEFWHSN---PSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
S S++ + S+ S+ S + + DS SDS S S S + + S
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 121 SDRESSITNDMGFSDDFS 138
SD SS ++D S D S
Sbjct: 969 SDSNSSDSSDSSNSSDSS 986
Score = 39.7 bits (91), Expect = 0.020
Identities = 34/141 (24%), Positives = 58/141 (41%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
++ N S +S + +D + ++++ SS+ D +S DS+ DSS
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + +S+ S S D S + S + S +S S+ S S S S S
Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSD 1071
Score = 39.7 bits (91), Expect = 0.020
Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S E S DS+ DSS
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS + SDS S DS S+ S S S S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSS--DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1162 SS-DSSDSSDSSDSSDSS 1178
Score = 39.7 bits (91), Expect = 0.020
Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD E S S++ S S + S DS+ DSS
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S DS + SDS S DS S+ S ES+ S
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDS-SDSSDSSDSSDSN-ESSDSSDSSDS 1243
Query: 123 RESSITNDMGFSDDFSLLESQERCEEE 149
+SS ++D S D S S E +
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESD 1270
Score = 39.3 bits (90), Expect = 0.026
Identities = 40/135 (29%), Positives = 58/135 (42%), Gaps = 3/135 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N N + ++ K +S + + + + ++ SSD D S DSN+ DSS +
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS-SDSDSSDSDS 587
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S++ SN S S DS + SDS DS S S + S S SD
Sbjct: 588 SDSSDSDSSD-SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDS 645
Query: 124 ESSITNDMGFSDDFS 138
SS ++D S D S
Sbjct: 646 NSSDSSDNSDSSDSS 660
Score = 39.3 bits (90), Expect = 0.026
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 5/146 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
DN + + ++ +SD + S +S++ S+ S + S +S+ DSS +
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711
Query: 63 LSFKSE----NQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFS 118
S S+ N + SN S S + DS + SDS S DS S+ S S S S
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSSNSSDSSDS 770
Query: 119 VHSDRESSITNDMGFSDDFSLLESQE 144
S S +N +D + +S +
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSD 796
Score = 39.3 bits (90), Expect = 0.026
Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 1/132 (0%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S NS + +D + + ++ SSD + + DS+ DSS
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S S D S + SDS S DS S+ S S S S +
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS-SNSSDSSDSSNSSDSSESSNSSDNSN 934
Query: 124 ESSITNDMGFSD 135
S +N SD
Sbjct: 935 SSDSSNSSDSSD 946
Score = 39.3 bits (90), Expect = 0.026
Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDR-HSLDSNTPLFPEDSSVGE 62
+D + S++ + NS + +D + + ++ SSD D +S DS+ DSS
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S + S+ S S D S DS + SDS + S S S + S S
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 122 D-RESSITNDMGFSDDFS 138
D ESS ++D S D S
Sbjct: 1080 DSSESSDSSDSSNSSDSS 1097
Score = 39.3 bits (90), Expect = 0.026
Identities = 37/141 (26%), Positives = 54/141 (38%), Gaps = 2/141 (1%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D N S NS + +D + + ++ SS+ S + S DS+ DSS
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSNSSDSSNSSD 1026
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S S D S S S DS S+ S S S S S
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSD 1107
Score = 38.9 bits (89), Expect = 0.033
Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 3/143 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S +SD + + +S + ++ SSD S + +S DS+ DSS
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 64 S--FKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S KS++ + S+ S D S +S + SD+ S DS S+ S S S S S
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN-SDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 122 DRESSITNDMGFSDDFSLLESQE 144
S +N SD S E
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSE 700
Score = 38.9 bits (89), Expect = 0.033
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLED---RHSLDSNTPLFPEDSSV 60
+ N S + NS + +D + ++++ SSD D +S DS+ DSS
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFS 118
S S + + S+ S+ S + DS + SDS S DS S S S S S
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 119 VH-SDRESSITNDMGFSDDFS 138
+ SD +SS +++ S D S
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSS 918
Score = 38.9 bits (89), Expect = 0.033
Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 4/138 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
++ + + D+ +SD + + +S +S + +S S E +S D++ +SS
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD-SSESSNSSDNSNSSDSSNSSDSS 945
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS- 121
S S N + +S+ S S D S +S + SDS S DS S+ S S S S +S
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 122 -DRESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1005 DSSDSSDSSDSSNSSDSS 1022
Score = 38.9 bits (89), Expect = 0.033
Identities = 41/136 (30%), Positives = 59/136 (43%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + ++ +SD + S S++ S S + S DS+ DSS
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N + S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSS--DSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1191 -DSSDSSDSSDSSDSS 1205
Score = 38.9 bits (89), Expect = 0.033
Identities = 36/142 (25%), Positives = 54/142 (38%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
++ + + D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S + S S DS S+ S S S S S
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S ++ SD +S E
Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNE 1233
Score = 38.5 bits (88), Expect = 0.044
Identities = 33/136 (24%), Positives = 55/136 (40%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD S S+N S S S +S+ DSS +
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ S+ S+ S DS + SDS S ++ +S+ S +
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 123 RESSITNDMGFSDDFS 138
+SS +N+ S D S
Sbjct: 880 SDSSDSNESSNSSDSS 895
Score = 38.5 bits (88), Expect = 0.044
Identities = 34/144 (23%), Positives = 56/144 (38%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + ++ ++ + ++ S+ S + +S DS+ DSS
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S S D S S S DS S+ S S S S +S
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 124 ESSITNDMGFSDDFSLLESQERCE 147
S ++ SD +S + E
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSE 1083
Score = 38.5 bits (88), Expect = 0.044
Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 1/136 (0%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S S S DS S+ S S S S S
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1152 -DSSDSSDSSDSSDSS 1166
Score = 38.5 bits (88), Expect = 0.044
Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 1/136 (0%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S+ S + S DS+ DSS
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S S S DS S+ S S S S S
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1209 -DSSDSSDSSDSSDSS 1223
Score = 38.1 bits (87), Expect = 0.057
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 2/136 (1%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S++ S+ S + S +S+ DSS
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + SN S S DS + SDS S DS S+ S S S S +S
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1026 -DSSNSSDSSDSSDSS 1040
Score = 38.1 bits (87), Expect = 0.057
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 3/142 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + +S DS+ DSS +
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS--D 1155
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ + S+ S S + DS + SDS S DS S+ S S S S S
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSS 1214
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S ++ SD ES +
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSD 1236
Score = 37.7 bits (86), Expect = 0.074
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 7/137 (5%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S++ + +S ++D + + ++ SS+ S + S DSN DSS
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN--SSDSSDSSDSNESSNSSDSSDSSN 899
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVHS 121
S S++ + SN S S + DS E S+S S DS S+ S S S S S
Sbjct: 900 SSDSDSSDS---SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 122 DRESSITNDMGFSDDFS 138
S +N SD S
Sbjct: 957 SNSSDSSNSSDSSDSNS 973
Score = 37.7 bits (86), Expect = 0.074
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +S+ + S S+N S S + +S DS+ DSS
Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + S+ S S D S DS + SDS S+ DS S+ S S S S
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1105 SS-DSSDSSDSSDSSDSS 1121
Score = 37.7 bits (86), Expect = 0.074
Identities = 38/142 (26%), Positives = 57/142 (40%), Gaps = 6/142 (4%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + ++ +SD + S S++ S S + S DS+ DSS +
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS--D 1077
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S SE+ + SN S S DS + SDS DS S+ S S S S S
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS----DSSDSSDSSNSSDSSDSSDSS 1133
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSD 1155
Score = 37.7 bits (86), Expect = 0.074
Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ ++SD S S++ S S + S DS+ DSS
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSS--DSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1188 -DSSDSSDSSDSSDSS 1202
Score = 37.4 bits (85), Expect = 0.097
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S++ S S + +S DS+ + S+ +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS--SDSSNSSD 1032
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S++ + S+ S S + DS + SDS S DS S+ S S S S +
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1093 SS-DSSDSSDSSDSSDSS 1109
Score = 37.0 bits (84), Expect = 0.13
Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 4/141 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D + + ++ SSD S + +S DS+ DSS
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD--SNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + SN S S DS SDS S DS + S S +S S +S
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS-SDSSDSSDGSDSD-SSNRSDSSNSSD 866
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD +S E
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNE 887
Score = 37.0 bits (84), Expect = 0.13
Identities = 34/141 (24%), Positives = 55/141 (39%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+ N S +S +D + ++++ SSD S + S +S+ DSS
Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S N + S+ S S + S + S + S DS S+ S S S S S
Sbjct: 997 SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD +S +
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSD 1077
Score = 37.0 bits (84), Expect = 0.13
Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S++ S S + S DS+ +SS
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S +S + + S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSS--DSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1203 -DSSDSSDSSDSSDSS 1217
Score = 37.0 bits (84), Expect = 0.13
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 4/149 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
++ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS + SDS S DS S+ S + S S
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEE 149
S S +N SD +S +E
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268
Score = 36.6 bits (83), Expect = 0.17
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 3/142 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + +S DS+ DSS
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN-SSDSSNSSDSSDSSNSSDSSDSS 845
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S + + S+ S+ S DS SDS S DS S+ S S S S SD
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S +N SD + +S E
Sbjct: 905 SSDS-SNSSDSSDSSNSSDSSE 925
Score = 36.6 bits (83), Expect = 0.17
Identities = 33/135 (24%), Positives = 50/135 (37%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S +S + +D + S S+N S S S DS+ DS
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S+ S DS E S+S S S +S+ S
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 124 ESSITNDMGFSDDFS 138
SS +++ S D S
Sbjct: 919 NSSDSSESSNSSDNS 933
Score = 36.6 bits (83), Expect = 0.17
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S++ NS + ++ + ++++ SSD D DS+ +SS
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S N + S+ S+ S + S DS + S+S DS S+ S S S S S
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSS--DSSDSSNSSDS--DSSDSSNSSDSSDSSNSSDSSE 925
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S+ +++ SD + +S +
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSD 946
Score = 36.6 bits (83), Expect = 0.17
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 5/135 (3%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S +S + +D + S+N S S + S DS+ DSS
Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + +S+ S S + DS + S+S DS S+ S S S S +S
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS----DSSESSNSSDNSNSSDSSNSS- 942
Query: 124 ESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 943 DSSDSSDSSNSSDSS 957
Score = 36.6 bits (83), Expect = 0.17
Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 3/137 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSS-VG 61
++ + + D+ +SD S S++ S S + +S DS+ DSS
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 62 ELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
+ S S++ + SN S S DS + SDS S DS S+ S S S S S
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 122 DRESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1100 S-DSSDSSDSSDSSDSS 1115
Score = 35.8 bits (81), Expect = 0.28
Identities = 34/141 (24%), Positives = 52/141 (36%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+ + S NS + ++ + S++ S S + S DS+ DSS
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + +S+ S S D S S S DS S+ S S S S S
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD ES +
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSD 1086
Score = 35.4 bits (80), Expect = 0.37
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 4/127 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSS--- 59
D+ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 60 -VGELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFS 118
+ S S++ E S+ S S + DS + SDS DS + S +S +
Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280
Query: 119 VHSDRES 125
SD +S
Sbjct: 1281 NGSDSDS 1287
Score = 34.7 bits (78), Expect = 0.63
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +S+ + S S++ S S + S DS+ DSS +
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS--D 1098
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ + S+ S S + DS + SDS S S S +S++S
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS--DSSESSDSSDS 1156
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1157 SDSSDSSDSSDSSDSS 1172
Score = 34.3 bits (77), Expect = 0.82
Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
Query: 2 KDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVG 61
K + + + D+ +SD + +S ++++ SD + S DS++ DSS
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS----SDSSNS 601
Query: 62 ELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S + + S+ S S S + SDS S+ S ++ +++ S +
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 122 DRESSITNDMGFSDDFS 138
SS ++D S D S
Sbjct: 662 SSNSSDSSDSSDSSDSS 678
Score = 34.3 bits (77), Expect = 0.82
Identities = 29/135 (21%), Positives = 48/135 (35%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S +S + +D + S +S++ S D DS+ DSS
Sbjct: 550 SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD 609
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S + DS SDS +S+ S +
Sbjct: 610 SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669
Query: 124 ESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 670 DSSDSSDSSSSSDSS 684
>gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]
Length = 454
Score = 50.1 bits (118), Expect = 1e-05
Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 1054 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQ 1113
L G D S ++ ++ G+ + I H TC A + L++GS D T W+ +
Sbjct: 160 LLCTGSDDLSAKLWDVSTGQCVYGIQTH----TCAAVKFDEQKLVTGSFDNTVACWEWSS 215
Query: 1114 QGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
G ++ F+ GHT V SV + ELD+ VSGS D TV + + G + TL
Sbjct: 216 ------GARTQHFR---GHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTL 264
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 9/120 (7%)
Query: 1053 LLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCG-IHLISGSRDTTCMIWQI 1111
L+ + G D I++ + G ++ ++ H D+V L+ G + L+S SRD T IW +
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 1112 TQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
+ G K Q+L GH V IS + M S + + +V + +++ +R L
Sbjct: 184 NKHG--------KQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKL 235
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1046 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1105
VVSH + L + D I+ + GK + ++ H+D VTCLA D G L+SGS D +
Sbjct: 650 VVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHDCS 709
Query: 1106 CMIWQI 1111
+W +
Sbjct: 710 LRLWSL 715
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1046 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1105
VVSH + L + D I+ + GK + ++ H+D VTCLA D G L+SGS D +
Sbjct: 643 VVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHDCS 702
Query: 1106 CMIWQI 1111
+W +
Sbjct: 703 LRLWSL 708
>gi|157266266 WD repeat domain 86 [Homo sapiens]
Length = 376
Score = 48.9 bits (115), Expect = 3e-05
Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 35/179 (19%)
Query: 1040 ITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDY------- 1092
I +++ V ++ LFS+ Y D + +V S+ KG++ H + V LA
Sbjct: 99 IVNRILVANNQ---LFSSSY-DRTARVWSVDKGQMSREFRGHRNCVLTLAYSAPWDLPST 154
Query: 1093 -------CGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTEL 1145
G L++GS D T +WQ+ + Q L GHT VL + + T
Sbjct: 155 PCAEEAAAGGLLVTGSTDGTAKVWQVA---------SGCCHQTLRGHTGAVLCLVLDTPG 205
Query: 1146 DMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKT 1204
A +GS D T+ I G+ +R R S + L + N +VYS + ++T
Sbjct: 206 HTAFTGSTDATIRAWDILSGEQLRVFREHRGSVICLELVNR--------LVYSGSADRT 256
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 48.5 bits (114), Expect = 4e-05
Identities = 43/162 (26%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 1047 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1106
V +D + + S Y D ++V + + H + V L D GIH++SGS DT+
Sbjct: 389 VQYDGRRVVSGAY-DFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSI 445
Query: 1107 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
+W + + L GH + L+ G+ + ++ VSG+ D TV I I+ GQ
Sbjct: 446 RVWDVETGNCI---------HTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQ 494
Query: 1167 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD 1208
++TL+ P + +T + + + V+ SS + L D
Sbjct: 495 CLQTLQGPNKHQSAVT----CLQFNKNFVITSSDDGTVKLWD 532
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/273 (21%), Positives = 110/273 (40%), Gaps = 46/273 (16%)
Query: 1057 AGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGG 1116
+G DN+++V S GK + ++ H V ++ +ISGS D T +W
Sbjct: 278 SGSDDNTLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAE---- 331
Query: 1117 VPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCE 1176
+ LYGHT+ V + + + VSGSRD T+ + I+ GQ + L
Sbjct: 332 -----TGECIHTLYGHTSTVRCMHLHEK--RVVSGSRDATLRVWDIETGQCLHVLMGHVA 384
Query: 1177 SSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDIC 1235
+ + ++G VV + + + D + L ++ G +V +
Sbjct: 385 AV-------RCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGH-------TNRVYSLQ 430
Query: 1236 IIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVV 1295
G H+V+GS+ + + D+ + N C+ + + G+E I+V
Sbjct: 431 FDGIHVVSGSLDTSIRVWDVETGN-------------CIHTLTGHQSLTSGMELKDNILV 477
Query: 1296 -----GVGKPAEMRSGQLSRKFWGSSKRLSQIS 1323
K ++++GQ + G +K S ++
Sbjct: 478 SGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 510
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 13/88 (14%)
Query: 1084 IVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGIST 1143
++TCL +CG ++SGS D T +W + K + L GHT V S +
Sbjct: 265 VITCL--QFCGNRIVSGSDDNTLKVWS---------AVTGKCLRTLVGHTGGVWSSQMRD 313
Query: 1144 ELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
++ +SGS D T+ + + G+ + TL
Sbjct: 314 --NIIISGSTDRTLKVWNAETGECIHTL 339
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 1041 TSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISG 1100
T++++ + D + S G D SI+V + G I + H + + + + L+SG
Sbjct: 423 TNRVYSLQFDGIHVVS-GSLDTSIRVWDVETGNCIHTLTGHQSLTSGM--ELKDNILVSG 479
Query: 1101 SRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG-ISTELDMAVSGSRDGTVII 1159
+ D+T IW I + Q L G +V + + ++ S DGTV +
Sbjct: 480 NADSTVKIWDIK---------TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKL 530
Query: 1160 HTIQKGQYMRTL 1171
++ G+++R L
Sbjct: 531 WDLKTGEFIRNL 542
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 48.5 bits (114), Expect = 4e-05
Identities = 43/162 (26%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 1047 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1106
V +D + + S Y D ++V + + H + V L D GIH++SGS DT+
Sbjct: 507 VQYDGRRVVSGAY-DFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSI 563
Query: 1107 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
+W + + L GH + L+ G+ + ++ VSG+ D TV I I+ GQ
Sbjct: 564 RVWDVETGNCI---------HTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQ 612
Query: 1167 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD 1208
++TL+ P + +T + + + V+ SS + L D
Sbjct: 613 CLQTLQGPNKHQSAVT----CLQFNKNFVITSSDDGTVKLWD 650
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/273 (21%), Positives = 110/273 (40%), Gaps = 46/273 (16%)
Query: 1057 AGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGG 1116
+G DN+++V S GK + ++ H V ++ +ISGS D T +W
Sbjct: 396 SGSDDNTLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAE---- 449
Query: 1117 VPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCE 1176
+ LYGHT+ V + + + VSGSRD T+ + I+ GQ + L
Sbjct: 450 -----TGECIHTLYGHTSTVRCMHLHEK--RVVSGSRDATLRVWDIETGQCLHVLMGHVA 502
Query: 1177 SSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDIC 1235
+ + ++G VV + + + D + L ++ G +V +
Sbjct: 503 AV-------RCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGH-------TNRVYSLQ 548
Query: 1236 IIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVV 1295
G H+V+GS+ + + D+ + N C+ + + G+E I+V
Sbjct: 549 FDGIHVVSGSLDTSIRVWDVETGN-------------CIHTLTGHQSLTSGMELKDNILV 595
Query: 1296 -----GVGKPAEMRSGQLSRKFWGSSKRLSQIS 1323
K ++++GQ + G +K S ++
Sbjct: 596 SGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 628
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 13/88 (14%)
Query: 1084 IVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGIST 1143
++TCL +CG ++SGS D T +W + K + L GHT V S +
Sbjct: 383 VITCL--QFCGNRIVSGSDDNTLKVWS---------AVTGKCLRTLVGHTGGVWSSQMRD 431
Query: 1144 ELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
++ +SGS D T+ + + G+ + TL
Sbjct: 432 --NIIISGSTDRTLKVWNAETGECIHTL 457
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 1041 TSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISG 1100
T++++ + D + S G D SI+V + G I + H + + + + L+SG
Sbjct: 541 TNRVYSLQFDGIHVVS-GSLDTSIRVWDVETGNCIHTLTGHQSLTSGM--ELKDNILVSG 597
Query: 1101 SRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG-ISTELDMAVSGSRDGTVII 1159
+ D+T IW I + Q L G +V + + ++ S DGTV +
Sbjct: 598 NADSTVKIWDIK---------TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKL 648
Query: 1160 HTIQKGQYMRTL 1171
++ G+++R L
Sbjct: 649 WDLKTGEFIRNL 660
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 48.5 bits (114), Expect = 4e-05
Identities = 43/162 (26%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 1047 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1106
V +D + + S Y D ++V + + H + V L D GIH++SGS DT+
Sbjct: 427 VQYDGRRVVSGAY-DFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSI 483
Query: 1107 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
+W + + L GH + L+ G+ + ++ VSG+ D TV I I+ GQ
Sbjct: 484 RVWDVETGNCI---------HTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQ 532
Query: 1167 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD 1208
++TL+ P + +T + + + V+ SS + L D
Sbjct: 533 CLQTLQGPNKHQSAVT----CLQFNKNFVITSSDDGTVKLWD 570
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/273 (21%), Positives = 110/273 (40%), Gaps = 46/273 (16%)
Query: 1057 AGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGG 1116
+G DN+++V S GK + ++ H V ++ +ISGS D T +W
Sbjct: 316 SGSDDNTLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAE---- 369
Query: 1117 VPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCE 1176
+ LYGHT+ V + + + VSGSRD T+ + I+ GQ + L
Sbjct: 370 -----TGECIHTLYGHTSTVRCMHLHEK--RVVSGSRDATLRVWDIETGQCLHVLMGHVA 422
Query: 1177 SSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDIC 1235
+ + ++G VV + + + D + L ++ G +V +
Sbjct: 423 AV-------RCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGH-------TNRVYSLQ 468
Query: 1236 IIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVV 1295
G H+V+GS+ + + D+ + N C+ + + G+E I+V
Sbjct: 469 FDGIHVVSGSLDTSIRVWDVETGN-------------CIHTLTGHQSLTSGMELKDNILV 515
Query: 1296 -----GVGKPAEMRSGQLSRKFWGSSKRLSQIS 1323
K ++++GQ + G +K S ++
Sbjct: 516 SGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 548
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 13/88 (14%)
Query: 1084 IVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGIST 1143
++TCL +CG ++SGS D T +W + K + L GHT V S +
Sbjct: 303 VITCL--QFCGNRIVSGSDDNTLKVWS---------AVTGKCLRTLVGHTGGVWSSQMRD 351
Query: 1144 ELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
++ +SGS D T+ + + G+ + TL
Sbjct: 352 --NIIISGSTDRTLKVWNAETGECIHTL 377
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 1041 TSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISG 1100
T++++ + D + S G D SI+V + G I + H + + + + L+SG
Sbjct: 461 TNRVYSLQFDGIHVVS-GSLDTSIRVWDVETGNCIHTLTGHQSLTSGM--ELKDNILVSG 517
Query: 1101 SRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG-ISTELDMAVSGSRDGTVII 1159
+ D+T IW I + Q L G +V + + ++ S DGTV +
Sbjct: 518 NADSTVKIWDIK---------TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKL 568
Query: 1160 HTIQKGQYMRTL 1171
++ G+++R L
Sbjct: 569 WDLKTGEFIRNL 580
>gi|142976686 nuclear autoantigen isoform 1 [Homo sapiens]
Length = 797
Score = 47.8 bits (112), Expect = 7e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1046 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1105
VVSH + + D I+ GK+I ++ H+D VT LA D GI+L+SGS D +
Sbjct: 687 VVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCS 746
Query: 1106 CMIWQI 1111
+W +
Sbjct: 747 IRLWNL 752
Score = 33.1 bits (74), Expect = 1.8
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
Query: 1081 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPV----GLASKPFQILYGHTNEV 1136
H D V LA L++ S D T +W + Q VP L +P H V
Sbjct: 479 HFDGVRALAFHPVEPVLVTASEDHTLKLWNL--QKTVPAKKSASLDVEPIYTFRAHIGPV 536
Query: 1137 LSVGISTELDMAVSGSRDGTV 1157
LS+ IS+ + SG D T+
Sbjct: 537 LSLAISSNGEQCFSGGIDATI 557
>gi|142976675 nuclear autoantigen isoform 2 [Homo sapiens]
Length = 713
Score = 47.8 bits (112), Expect = 7e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1046 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1105
VVSH + + D I+ GK+I ++ H+D VT LA D GI+L+SGS D +
Sbjct: 603 VVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCS 662
Query: 1106 CMIWQI 1111
+W +
Sbjct: 663 IRLWNL 668
Score = 33.1 bits (74), Expect = 1.8
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
Query: 1081 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPV----GLASKPFQILYGHTNEV 1136
H D V LA L++ S D T +W + Q VP L +P H V
Sbjct: 395 HFDGVRALAFHPVEPVLVTASEDHTLKLWNL--QKTVPAKKSASLDVEPIYTFRAHIGPV 452
Query: 1137 LSVGISTELDMAVSGSRDGTV 1157
LS+ IS+ + SG D T+
Sbjct: 453 LSLAISSNGEQCFSGGIDATI 473
>gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [Homo
sapiens]
Length = 514
Score = 47.4 bits (111), Expect = 9e-05
Identities = 42/156 (26%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 1016 IKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKII 1075
IK + + K + S+ G + T + +VS + LFS G D ++ L K+I
Sbjct: 228 IKIWDLASGKLKLSLTGHIS-----TVRGVIVSTRSPYLFSCGE-DKQVKCWDLEYNKVI 281
Query: 1076 SHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNE 1135
H H+ V L L++ SRD+T IW + + V L GHTN
Sbjct: 282 RHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASV---------HTLSGHTNA 332
Query: 1136 VLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
V +V ++GS D T+ + + G+ TL
Sbjct: 333 VATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 368
Score = 36.2 bits (82), Expect = 0.22
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 9/117 (7%)
Query: 1055 FSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQ 1114
F G D +I++ L GK+ + H+ V + +L S D W +
Sbjct: 219 FVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEY- 277
Query: 1115 GGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1171
+K + +GH + V + + +D+ V+ SRD T I ++ + TL
Sbjct: 278 --------NKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTL 326
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 46.6 bits (109), Expect = 2e-04
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 1052 KLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCG-IHLISGSRDTTCMIWQ 1110
+LL + G + I++ + GK++ +++ H ++V L G + L+S SRD T +W
Sbjct: 140 QLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWD 199
Query: 1111 ITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRT 1170
+ G + ++L GH N V S S + M S V + + K +R
Sbjct: 200 LKDDGNM--------MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRK 251
Query: 1171 L 1171
L
Sbjct: 252 L 252
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 46.2 bits (108), Expect = 2e-04
Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 30/178 (16%)
Query: 1061 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVG 1120
D I++ GK I H ++ +A L+S S D T IW ++
Sbjct: 66 DKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVS-------- 117
Query: 1121 LASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLF 1180
+ K + L GH+N V + + ++ VSGS D +V I ++ G+ ++TL P S
Sbjct: 118 -SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL--PAHSD-- 172
Query: 1181 LTIPNLAISWEGHIVVYSSTEE-------------KTTLKDKN---ALHLFSINGKYL 1222
+ + + +G ++V SS + KT + D N + FS NGKY+
Sbjct: 173 -PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229
Score = 34.3 bits (77), Expect = 0.82
Identities = 16/56 (28%), Positives = 29/56 (51%)
Query: 1054 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIW 1109
L +G +D S+++ + GK + + H D V+ + + G ++S S D C IW
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 12/81 (14%)
Query: 1061 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYC---GIHLISGSRDTTCMIWQITQQGGV 1117
DN++++ +KGK + H + C+ ++ G ++SGS D IW + + V
Sbjct: 235 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV 294
Query: 1118 PVGLASKPFQILYGHTNEVLS 1138
Q L GHT+ V+S
Sbjct: 295 ---------QKLQGHTDVVIS 306
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 46.2 bits (108), Expect = 2e-04
Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 30/178 (16%)
Query: 1061 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVG 1120
D I++ GK I H ++ +A L+S S D T IW ++
Sbjct: 66 DKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVS-------- 117
Query: 1121 LASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLF 1180
+ K + L GH+N V + + ++ VSGS D +V I ++ G+ ++TL P S
Sbjct: 118 -SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL--PAHSD-- 172
Query: 1181 LTIPNLAISWEGHIVVYSSTEE-------------KTTLKDKN---ALHLFSINGKYL 1222
+ + + +G ++V SS + KT + D N + FS NGKY+
Sbjct: 173 -PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229
Score = 34.3 bits (77), Expect = 0.82
Identities = 16/56 (28%), Positives = 29/56 (51%)
Query: 1054 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIW 1109
L +G +D S+++ + GK + + H D V+ + + G ++S S D C IW
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 12/81 (14%)
Query: 1061 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYC---GIHLISGSRDTTCMIWQITQQGGV 1117
DN++++ +KGK + H + C+ ++ G ++SGS D IW + + V
Sbjct: 235 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV 294
Query: 1118 PVGLASKPFQILYGHTNEVLS 1138
Q L GHT+ V+S
Sbjct: 295 ---------QKLQGHTDVVIS 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,456,734
Number of Sequences: 37866
Number of extensions: 2213689
Number of successful extensions: 7383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 6629
Number of HSP's gapped (non-prelim): 649
length of query: 1335
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1221
effective length of database: 13,930,794
effective search space: 17009499474
effective search space used: 17009499474
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.