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Search of human proteins with 153070822
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153070822 methylmalonic aciduria (cobalamin deficiency) cblC
type, with homocystinuria [Homo sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153070822 methylmalonic aciduria (cobalamin deficiency) cblC ... 596 e-171
gi|166795252 hypothetical protein LOC23359 [Homo sapiens] 40 0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 38 0.009
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 38 0.009
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 38 0.009
gi|239582763 ral guanine nucleotide dissociation stimulator-like... 37 0.015
gi|9945318 MAX binding protein [Homo sapiens] 36 0.033
gi|239755589 PREDICTED: hypothetical protein [Homo sapiens] 35 0.097
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 34 0.13
gi|239582765 ral guanine nucleotide dissociation stimulator-like... 34 0.13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 34 0.13
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 34 0.16
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 34 0.16
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi... 34 0.16
gi|113429443 PREDICTED: transmembrane protein 46-like [Homo sapi... 34 0.16
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 34 0.16
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 34 0.16
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 33 0.22
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 33 0.22
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 33 0.28
gi|239756858 PREDICTED: hypothetical protein [Homo sapiens] 33 0.28
gi|150170729 microtubule associated serine/threonine kinase 3 [H... 33 0.28
gi|169207534 PREDICTED: hypothetical protein [Homo sapiens] 33 0.37
gi|51093874 proline rich 19 [Homo sapiens] 33 0.37
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 33 0.37
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 32 0.48
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 32 0.48
gi|163965366 nascent polypeptide-associated complex alpha subuni... 32 0.48
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 32 0.48
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 32 0.63
>gi|153070822 methylmalonic aciduria (cobalamin deficiency) cblC
type, with homocystinuria [Homo sapiens]
Length = 282
Score = 596 bits (1537), Expect = e-171
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MEPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFD 60
MEPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFD
Sbjct: 1 MEPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFD 60
Query: 61 RALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTA 120
RALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTA
Sbjct: 61 RALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTA 120
Query: 121 AHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPH 180
AHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPH
Sbjct: 121 AHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPH 180
Query: 181 DCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPS 240
DCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPS
Sbjct: 181 DCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPS 240
Query: 241 EKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
EKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP
Sbjct: 241 EKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
Length = 539
Score = 40.0 bits (92), Expect = 0.002
Identities = 26/63 (41%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 221 AYFSTP-PAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPAS 279
A FSTP PA +LL + SSPSPD P PAP +P P S P +
Sbjct: 329 AGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQ 388
Query: 280 PGP 282
PGP
Sbjct: 389 PGP 391
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 38.1 bits (87), Expect = 0.009
Identities = 25/60 (41%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 224 STPPAQRLALLGLAQPSEKPSSPSPDLPFT---TPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q L + P + P SPS LP + TP P+ P P A L SPPASP
Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPPSPPASP 581
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/60 (41%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q LAL L P P+SP P P TP+P+ P + A L SPP SP
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPSPQAPN--ALAVHLLQAPFSPPPSP 446
Score = 32.3 bits (72), Expect = 0.48
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 224 STPPAQRLALLG---LAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q +L L P P+SP T AP++P P S PR++ +P
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASP------TLQAPRRPPTPGPDTSVSGPRLTLALAP 609
Query: 281 GP 282
GP
Sbjct: 610 GP 611
Score = 30.4 bits (67), Expect = 1.8
Identities = 25/69 (36%), Positives = 28/69 (40%), Gaps = 12/69 (17%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPA---------PKKPGNPSRARSWLS 271
+TP Q LA+ L P P SP PF+ PA P PS A L
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
Query: 272 PRVSPPASP 280
SPPASP
Sbjct: 481 VPPSPPASP 489
Score = 29.6 bits (65), Expect = 3.1
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
Query: 224 STPPAQ---RLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP+Q LA L P P+SP P P TP P+ P P A L PP +P
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAP--PPLAAPPLQLAKPPPQAP 520
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 38.1 bits (87), Expect = 0.009
Identities = 25/60 (41%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 224 STPPAQRLALLGLAQPSEKPSSPSPDLPFT---TPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q L + P + P SPS LP + TP P+ P P A L SPPASP
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPPSPPASP 850
Score = 34.7 bits (78), Expect = 0.097
Identities = 26/60 (43%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP+Q LA L P P+SP P P TP P+ P P A L SPPASP
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAP--PPLAAPPLQVPPSPPASP 745
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/60 (41%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q LAL L P P+SP P P TP+P+ P + A L SPP SP
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASP-PLSPLATPSPQAPN--ALAVHLLQAPFSPPPSP 671
Score = 32.3 bits (72), Expect = 0.48
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 224 STPPAQRLALLG---LAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q +L L P P+SP T AP++P P S PR++ +P
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASP------TLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 281 GP 282
GP
Sbjct: 879 GP 880
Score = 30.8 bits (68), Expect = 1.4
Identities = 25/59 (42%), Positives = 28/59 (47%), Gaps = 6/59 (10%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPAS 279
+TPP Q LA L P P+SP P P TP P+ P P A L SPPAS
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASP-PMSPSATPPPRVP--PLLAAPPLQVPPSPPAS 775
Score = 30.4 bits (67), Expect = 1.8
Identities = 25/69 (36%), Positives = 28/69 (40%), Gaps = 12/69 (17%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPA---------PKKPGNPSRARSWLS 271
+TP Q LA+ L P P SP PF+ PA P PS A L
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 272 PRVSPPASP 280
SPPASP
Sbjct: 706 VPPSPPASP 714
Score = 29.6 bits (65), Expect = 3.1
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 243 PSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
P++ P P TP P P +PS S L SPPA+P
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPS-LQTLPSPPATP 364
Score = 28.1 bits (61), Expect = 9.0
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 2/59 (3%)
Query: 222 YFSTPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+ TPP A L P ++P P+ P + P P+ A L SPP SP
Sbjct: 557 HLETPPCP--APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 38.1 bits (87), Expect = 0.009
Identities = 25/60 (41%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 224 STPPAQRLALLGLAQPSEKPSSPSPDLPFT---TPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q L + P + P SPS LP + TP P+ P P A L SPPASP
Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPPSPPASP 542
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/60 (41%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q LAL L P P+SP P P TP+P+ P + A L SPP SP
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPSPQAPN--ALAVHLLQAPFSPPPSP 407
Score = 32.3 bits (72), Expect = 0.48
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 224 STPPAQRLALLG---LAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP Q +L L P P+SP T AP++P P S PR++ +P
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASP------TLQAPRRPPTPGPDTSVSGPRLTLALAP 570
Query: 281 GP 282
GP
Sbjct: 571 GP 572
Score = 31.2 bits (69), Expect = 1.1
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Query: 211 PQERYSEEQKAYFSTPPAQRLALLGLAQ--PSEKPSSPS----PDLPFTTPAPKKPGNPS 264
P R + A+ S P + L L Q P K ++P+ P TP+P P +PS
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307
Query: 265 RARSWLSPRVSPPASP 280
S L SPPA+P
Sbjct: 308 APPS-LQTLPSPPATP 322
Score = 30.4 bits (67), Expect = 1.8
Identities = 25/69 (36%), Positives = 28/69 (40%), Gaps = 12/69 (17%)
Query: 224 STPPAQR---LALLGLAQPSEKPSSPSPDLPFTTPA---------PKKPGNPSRARSWLS 271
+TP Q LA+ L P P SP PF+ PA P PS A L
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 272 PRVSPPASP 280
SPPASP
Sbjct: 442 VPPSPPASP 450
Score = 29.6 bits (65), Expect = 3.1
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
Query: 224 STPPAQ---RLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
+TPP+Q LA L P P+SP P P TP P+ P P A L PP +P
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAP--PPLAAPPLQLAKPPPQAP 481
>gi|239582763 ral guanine nucleotide dissociation stimulator-like 3
isoform 2 [Homo sapiens]
Length = 710
Score = 37.4 bits (85), Expect = 0.015
Identities = 35/96 (36%), Positives = 45/96 (46%), Gaps = 23/96 (23%)
Query: 208 AVTPQERYSEEQKAYFST---PPA----------QRLAL---LGLAQPSEKPSSPS---- 247
A+ Q + +EEQ S PPA +R++L L EK SSPS
Sbjct: 483 ALHAQNQLTEEQSYRLSRVIEPPAASCPSSPRIRRRISLTKRLSAKLAREKSSSPSGSPG 542
Query: 248 -PDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
P P ++ +P P PS RS +P SPPASPGP
Sbjct: 543 DPSSPTSSVSPGSP--PSSPRSRDAPAGSPPASPGP 576
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 36.2 bits (82), Expect = 0.033
Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 12/103 (11%)
Query: 192 LLEGFNF-HWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPSEKPSSPSPDL 250
LLE F W+ + A QER EQ+ A LA L P E+P +P L
Sbjct: 6 LLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPL 65
Query: 251 PFTTPAPKKPGNPSRARS-----------WLSPRVSPPASPGP 282
P + PAP P A SP+ PP P P
Sbjct: 66 PLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLP 108
>gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]
Length = 356
Score = 34.7 bits (78), Expect = 0.097
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 8/51 (15%)
Query: 235 GLAQPSEKPSSPSPDLPFTTPAPKKPGNPSR----ARSWLSPRVSPPASPG 281
G A+P S P+P L P P KPG+P++ A SW P S A PG
Sbjct: 177 GFAEPPGGSSPPAPPL----PPPPKPGSPTQRAREASSWKPPGHSHTAPPG 223
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
[Homo sapiens]
Length = 3969
Score = 34.3 bits (77), Expect = 0.13
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 214 RYSEEQKAYFSTPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNP-SRARSWLSP 272
RYS +++ F + ++L+ L A + SSP P L T P P +P + S WL P
Sbjct: 530 RYSVSERS-FGSRTTKKLSTLQSAPQQQTSSSPPPPL-LTPPPPLQPASSISDHTPWLMP 587
Query: 273 RVSPPASP 280
P ASP
Sbjct: 588 PTIPLASP 595
>gi|239582765 ral guanine nucleotide dissociation stimulator-like 3
isoform 1 [Homo sapiens]
Length = 716
Score = 34.3 bits (77), Expect = 0.13
Identities = 23/55 (41%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 230 RLALLGLAQPSEKPSSPSPDLPFTTPAPK-KPGNP-SRARSWLSPRVSPPASPGP 282
+LA + PS P PS +P PG+P S RS +P SPPASPGP
Sbjct: 528 KLAREKSSSPSGSPGDPSSPTSSLCISPSVSPGSPPSSPRSRDAPAGSPPASPGP 582
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 34.3 bits (77), Expect = 0.13
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 223 FSTPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSP--RVSPPASP 280
F PP + + PS P+ P P P +P P K G+P + S S PP +P
Sbjct: 916 FPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 33.9 bits (76), Expect = 0.16
Identities = 25/109 (22%), Positives = 41/109 (37%), Gaps = 21/109 (19%)
Query: 172 PDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRL 231
P +PP +P D T DW D ++ E ++ F P +
Sbjct: 354 PPVPPLRPRDRSSTEK-------------HDWDPPDRKVDTRKFRSEPRSIFEYEPGKS- 399
Query: 232 ALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
++L +P P++P TP P++PG + S L P+ P
Sbjct: 400 SILQHERPPPLPTTP-------TPVPREPGRKPLSSSRLGEVTGSPSPP 441
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 33.9 bits (76), Expect = 0.16
Identities = 25/109 (22%), Positives = 41/109 (37%), Gaps = 21/109 (19%)
Query: 172 PDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRL 231
P +PP +P D T DW D ++ E ++ F P +
Sbjct: 261 PPVPPLRPRDRSSTEK-------------HDWDPPDRKVDTRKFRSEPRSIFEYEPGKS- 306
Query: 232 ALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
++L +P P++P TP P++PG + S L P+ P
Sbjct: 307 SILQHERPPPLPTTP-------TPVPREPGRKPLSSSRLGEVTGSPSPP 348
>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
sapiens]
Length = 547
Score = 33.9 bits (76), Expect = 0.16
Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 10/45 (22%)
Query: 238 QPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
QP + PSPDLP P A W P +PPA+PGP
Sbjct: 440 QPPARAPRPSPDLPA----------PLDACPWAPPVYAPPAAPGP 474
>gi|113429443 PREDICTED: transmembrane protein 46-like [Homo
sapiens]
Length = 492
Score = 33.9 bits (76), Expect = 0.16
Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 10/45 (22%)
Query: 238 QPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
QP + PSPDLP P A W P +PPA+PGP
Sbjct: 385 QPPARAPRPSPDLPA----------PLDACPWAPPVYAPPAAPGP 419
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 33.9 bits (76), Expect = 0.16
Identities = 25/66 (37%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 219 QKAYFSTPPAQRLALLGLAQPSE--KPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSP 276
Q + PA L AQP E +P P P P T PAP + P RS SP+
Sbjct: 1077 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAG- 1135
Query: 277 PASPGP 282
A PGP
Sbjct: 1136 LAGPGP 1141
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 33.9 bits (76), Expect = 0.16
Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 226 PPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
PPAQR P + P S SP L +TPA +P + ++PR PPA P
Sbjct: 31 PPAQRAG-----SPPDAPGSESPALACSTPATPSGEDPPARAAPIAPR--PPARP 78
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 33.5 bits (75), Expect = 0.22
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
Query: 219 QKAYFSTPPAQRLALLGLAQPSE--KPSSPSPDLPFTTPA-PKKPGNPSRARSWLSPR-- 273
Q + PA L AQP E +P P P P T PA P++P PS ARS R
Sbjct: 1121 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKE 1180
Query: 274 ---VSPPASPG 281
+ P SPG
Sbjct: 1181 FGGIGAPPSPG 1191
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 33.5 bits (75), Expect = 0.22
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
Query: 219 QKAYFSTPPAQRLALLGLAQPSE--KPSSPSPDLPFTTPA-PKKPGNPSRARSWLSPR-- 273
Q + PA L AQP E +P P P P T PA P++P PS ARS R
Sbjct: 1121 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKE 1180
Query: 274 ---VSPPASPG 281
+ P SPG
Sbjct: 1181 FGGIGAPPSPG 1191
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 33.1 bits (74), Expect = 0.28
Identities = 27/68 (39%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Query: 219 QKAYFSTPPAQRLALLGLAQPSE--KPSSPSPDLPFTTPA-PKKPGNPSRARSWLSPR-- 273
Q + PA L AQP E +P P P P T PA P++P PS ARS R
Sbjct: 1082 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKE 1141
Query: 274 VSPPASPG 281
P SPG
Sbjct: 1142 FGAPKSPG 1149
>gi|239756858 PREDICTED: hypothetical protein [Homo sapiens]
Length = 118
Score = 33.1 bits (74), Expect = 0.28
Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 16/80 (20%)
Query: 210 TPQERYSEEQKAYFSTPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSW 269
TP+E+ + E A PP LG A PS P SP+ PF P P +SW
Sbjct: 19 TPKEKLANEAAAPGEGPP--HTPALG-ATPSPDPQQGSPERPFKEARPPPP------QSW 69
Query: 270 L-------SPRVSPPASPGP 282
L P + A+PGP
Sbjct: 70 LLAVADVFVPPSAEAAAPGP 89
>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
sapiens]
Length = 1309
Score = 33.1 bits (74), Expect = 0.28
Identities = 16/36 (44%), Positives = 20/36 (55%)
Query: 245 SPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASP 280
SPSP P +PAP P + + + SP S PASP
Sbjct: 1115 SPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASP 1150
>gi|169207534 PREDICTED: hypothetical protein [Homo sapiens]
Length = 183
Score = 32.7 bits (73), Expect = 0.37
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 234 LGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
L L+ P P P P P +P ++P P + PR PA PGP
Sbjct: 62 LHLSCPRASPDRPRPSCPLASPDRRRPAIPRASPD--RPRPISPAPPGP 108
>gi|51093874 proline rich 19 [Homo sapiens]
Length = 356
Score = 32.7 bits (73), Expect = 0.37
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 4/57 (7%)
Query: 224 STPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPS--RARSWLSPRVSPPA 278
+TPP R +GL QP +PSSP LP T+ P PS + SW+ + SP A
Sbjct: 293 ATPPPPRPWGVGLPQPLPQPSSPL--LPRTSVLDWSPSPPSPLPSLSWVVAQSSPEA 347
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 32.7 bits (73), Expect = 0.37
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 224 STPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
+TPPA A G + + P P PAP P+RA + + P SPGP
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGP 164
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 32.3 bits (72), Expect = 0.48
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 224 STPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPP---ASP 280
S PP L+G A P P P P P P+ P +P+ + S SP +SP
Sbjct: 756 SAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSP 815
Query: 281 GP 282
GP
Sbjct: 816 GP 817
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 32.3 bits (72), Expect = 0.48
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 237 AQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP 282
A P P P P P TP+P+ P P+R ++ LS +P +SP P
Sbjct: 472 AAPILGPGEPGPQAPSRTPSPRSPA-PARVKAELS-SPTPGSSPVP 515
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 32.3 bits (72), Expect = 0.48
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 10/67 (14%)
Query: 225 TPPAQRLALLGLAQ----PSEKPSSPS----PDLPFTTP-APKKPGNPSRARSWLSPRVS 275
TPPA L A P P++PS P LP TP +PK+P P + + SP+
Sbjct: 1434 TPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK-K 1492
Query: 276 PPASPGP 282
PA+P P
Sbjct: 1493 APATPAP 1499
Score = 28.5 bits (62), Expect = 6.9
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 9/85 (10%)
Query: 206 RDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPSEKPSSPSPDLP--------FTTPAP 257
+ A TP K +TPP + + P P+ P T P+P
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
Query: 258 K-KPGNPSRARSWLSPRVSPPASPG 281
K PG P + P V+PP+ G
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKG 1345
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 32.3 bits (72), Expect = 0.48
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 12/68 (17%)
Query: 224 STPPAQRLALLGLAQPSEKPSSP---------SPDLPFTTPAPKKPGNPSRARSWLSPRV 274
S+PPA L G P + P +P +P P P P P+R +S SP
Sbjct: 585 SSPPAPPLPP-GSGSPGTPQALPRRLVGSSLRAPTVP--PPLPPTPPQPARRQSRRSPAS 641
Query: 275 SPPASPGP 282
PASPGP
Sbjct: 642 PSPASPGP 649
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 32.0 bits (71), Expect = 0.63
Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 5/53 (9%)
Query: 235 GLAQPSEKPSSPSPDLPFTTPAPKK-----PGNPSRARSWLSPRVSPPASPGP 282
G+A P S P P A KK P SR + PRVSPP +P P
Sbjct: 706 GVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSP 758
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,026,609
Number of Sequences: 37866
Number of extensions: 775212
Number of successful extensions: 4920
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 187
Number of HSP's that attempted gapping in prelim test: 4396
Number of HSP's gapped (non-prelim): 698
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.