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Search of human proteins with 153070260
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153070260 myristoylated alanine-rich protein kinase C
substrate [Homo sapiens]
(332 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153070260 myristoylated alanine-rich protein kinase C substra... 642 0.0
gi|13491174 MARCKS-like 1 [Homo sapiens] 110 2e-24
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 101 8e-22
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 79 6e-15
gi|30795231 brain abundant, membrane attached signal protein 1 [... 75 8e-14
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 74 2e-13
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 73 3e-13
gi|122692281 hypothetical protein LOC645369 [Homo sapiens] 72 7e-13
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 71 2e-12
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 71 2e-12
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 71 2e-12
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 71 2e-12
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 70 2e-12
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 69 4e-12
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 65 6e-11
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 65 6e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens] 65 8e-11
gi|117938759 GNAS complex locus XLas [Homo sapiens] 64 2e-10
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 64 2e-10
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 62 5e-10
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 62 5e-10
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 62 9e-10
gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens] 62 9e-10
gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens] 62 9e-10
gi|13376611 zinc finger protein 703 [Homo sapiens] 61 1e-09
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 61 1e-09
gi|154146231 DMRT-like family A2 [Homo sapiens] 61 1e-09
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 61 1e-09
gi|157738619 smoothelin-like 1 [Homo sapiens] 61 1e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni... 60 3e-09
>gi|153070260 myristoylated alanine-rich protein kinase C substrate
[Homo sapiens]
Length = 332
Score = 642 bits (1655), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA 60
MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA
Sbjct: 1 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA 60
Query: 61 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 120
NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT
Sbjct: 61 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 120
Query: 121 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE 180
AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE
Sbjct: 121 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE 180
Query: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ
Sbjct: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
Query: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 300
EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE
Sbjct: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 300
Query: 301 PAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
PAAAAASSACAAPSQEAQPECSPEAPPAEAAE
Sbjct: 301 PAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
>gi|13491174 MARCKS-like 1 [Homo sapiens]
Length = 195
Score = 110 bits (275), Expect = 2e-24
Identities = 91/265 (34%), Positives = 117/265 (44%), Gaps = 72/265 (27%)
Query: 1 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA 60
MG+Q SK A +G+ AE A +SP+KANGQENGHVK NGD S
Sbjct: 1 MGSQSSK-APRGDVTAEE----AAGASPAKANGQENGHVKSNGDLS-------------- 41
Query: 61 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 120
P + E P G+ A+ + + EPA P + A A+GE
Sbjct: 42 ----PKGEGESPPVNGTDEAAGATGDAIEPA----------PPSQGAEAKGEV------- 80
Query: 121 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE 180
P ETPKKKKK FSFKK FKLSG SFK+N+KE G
Sbjct: 81 -------------------------PPKETPKKKKK-FSFKKPFKLSGLSFKRNRKEGGG 114
Query: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAP--GEEAAAGEEGAAGGDPQEAK 238
A +P E ++ G A + E A G+ AA P E A G E +A + +EA
Sbjct: 115 DSSASSPTEE---EQEQGEIGACSDEGTAQEGKAAATPESQEPQAKGAEASAASE-EEAG 170
Query: 239 PQEAAVAPEKPPASDETKAAEEPSK 263
PQ + P S T A+ E ++
Sbjct: 171 PQATEPSTPSGPESGPTPASAEQNE 195
Score = 38.9 bits (89), Expect = 0.006
Identities = 41/175 (23%), Positives = 71/175 (40%), Gaps = 30/175 (17%)
Query: 184 AEAPAAEGGKDEAAGGAAAAA--AEAG----------AASGEQAAAPGEEAAAGEEGAA- 230
++AP + +EAAG + A A E G GE G + AAG G A
Sbjct: 6 SKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLSPKGEGESPPVNGTDEAAGATGDAI 65
Query: 231 -GGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVE----EKKAEEAGASAAAC------ 279
P + + V P++ P + + ++P K+ ++ +E G ++A
Sbjct: 66 EPAPPSQGAEAKGEVPPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASSPTEEE 125
Query: 280 ----EAPSAAGPGAPPEQEAA--PAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
E + + G E +AA P + A + A AA +EA P+ + + P+
Sbjct: 126 QEQGEIGACSDEGTAQEGKAAATPESQEPQAKGAEASAASEEEAGPQATEPSTPS 180
Score = 36.6 bits (83), Expect = 0.032
Identities = 45/161 (27%), Positives = 62/161 (38%), Gaps = 33/161 (20%)
Query: 173 KNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAA--PGEEAAAGEEGAA 230
K+ + GE E+P G DEAAG A A + G +A P +E ++ +
Sbjct: 35 KSNGDLSPKGEGESPPVNG-TDEAAGATGDAIEPAPPSQGAEAKGEVPPKETPKKKKKFS 93
Query: 231 -------------------GGDPQEAKPQEAAV------APEKPPASDETKAAEEPSKVE 265
GGD + P E A + E KAA P +
Sbjct: 94 FKKPFKLSGLSFKRNRKEGGGDSSASSPTEEEQEQGEIGACSDEGTAQEGKAAATPES-Q 152
Query: 266 EKKAEEAGASAAACE--APSAAGPGAPPEQEAAPAEEPAAA 304
E +A+ A ASAA+ E P A P P E+ P PA+A
Sbjct: 153 EPQAKGAEASAASEEEAGPQATEPSTPSGPESGPT--PASA 191
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 101 bits (252), Expect = 8e-22
Identities = 109/368 (29%), Positives = 152/368 (41%), Gaps = 46/368 (12%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDA-SPAAAESGAKEELQANGSA 64
++ AA E A+ P + A SP++A E K + SP A+S AKEE ++ A
Sbjct: 506 AEEAASPEKEAKSPVKEE-AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 65 PAADKEE---PAAAGS--GAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSP 119
+ +KEE PA S A SP+ E PA A +PE SPV++EA + EA P
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 120 TAAEGEAASAASSTSSPKAEDGATP----SPSNETPKKKKKRFSFKKSFKLSGFSFKKN- 174
A + SP E+ +P SP E K +K S K+ S K
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684
Query: 175 KKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDP 234
K EA +A++P E K A + + A S E+A +P +E A E A
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPE---KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 235 QEAKPQEAAVAPE------------KPPASDETKA--------AEEPSKVEEKKAEEA-- 272
+EAK E A +PE K PA +E ++ A+ P K E K E+A
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801
Query: 273 ----GASAAACEAPSAAGPGAPPEQEAAP-----AEEPAAAAASSACAAPSQEAQPECSP 323
A A E P +P ++E P E P A A A P E + +
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 324 EAPPAEAA 331
E P + A
Sbjct: 862 EEAPKKEA 869
Score = 85.9 bits (211), Expect = 5e-17
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 30/332 (9%)
Query: 4 QFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGS 63
Q +T E E EA + G+E + AE A E +A
Sbjct: 460 QTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP 519
Query: 64 APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAE 123
+E A + + A SP E PA +PE SP ++EA + EA P A
Sbjct: 520 V-----KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 124 GEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGE 183
+ SP E+ +P+ + ++P+K K K+EA E
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEA-KSPEKAKSPV----------------KEEAKSPAE 617
Query: 184 AEAPAAEGGKDEA---AGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
A++P E K A + A + + A S E+A +P +E A E A EAK
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP 677
Query: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEA---AP 297
E A +P K A K A+ P K EE K+ E S EA S +P ++EA
Sbjct: 678 EKAKSPVKAEAKSPEK-AKSPVK-EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 298 AEEPAAAAASSACAAPSQEAQPECSPEAPPAE 329
A+ P A S A S E ++P A+
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAK 767
Score = 77.0 bits (188), Expect = 2e-14
Identities = 93/345 (26%), Positives = 136/345 (39%), Gaps = 41/345 (11%)
Query: 6 SKTAAKGEAAAERPGEAAV---ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANG 62
+K+ K EA + ++ V A SP KA K +P A+S KEE ++
Sbjct: 694 AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK-----TPEKAKSPVKEEAKSPE 748
Query: 63 SAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAA 122
A + +K + S A A E+ A PE SPV++E + +A P A
Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808
Query: 123 EGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKK------NKK 176
A PK E+ +P E P++ K + KK+ + + K +KK
Sbjct: 809 -------APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 177 EAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGE---QAAAPGEEAAAGEEGAAGGD 233
E EA P E K+ A + EA E + P +EA A E
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK---- 917
Query: 234 PQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQ 293
++AKP+E +K P D+ K A+EPSK EKK EA + A P P+
Sbjct: 918 -EDAKPKEKTEVAKKEP--DDAK-AKEPSKPAEKK--EAAPEKKDTKEEKAKKPEEKPKT 971
Query: 294 EAAPAE-------EPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331
EA E EP+ A A + S + + PE + A
Sbjct: 972 EAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKA 1016
Score = 71.2 bits (173), Expect = 1e-12
Identities = 82/308 (26%), Positives = 120/308 (38%), Gaps = 27/308 (8%)
Query: 38 HVKVNGDASPAAAESGAKEEL-------QANGSAPAADKEEPAAAGSGAASPSAAEKGEP 90
H+KV + E KE + + + ++EE A E+ E
Sbjct: 435 HIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE-EE 493
Query: 91 AAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNET 150
A E + P E+ A E EA P E A + + SP+ E+ +P+ E
Sbjct: 494 AEGGEEETKSPPAEEAASPEKEAKSPVK------EEAKSPAEAKSPEKEEAKSPA---EV 544
Query: 151 PKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP--AAEGGKDEAAGGAAAAAAE-A 207
+K + K+ K + K+EA E ++P A K+EA A A + E A
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604
Query: 208 GAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEK 267
+ E+A +P E + +E A P E K E A +P K A K A+ P K EE
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAK--SPAEVKSPEKAKSPTKEEAKSPEK-AKSPEK-EEA 660
Query: 268 KAEEAGASAAACEAPSAAGPGAPPEQEA---APAEEPAAAAASSACAAPSQEAQPECSPE 324
K+ E S EA S +P + EA A+ P A S A S + SPE
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 325 APPAEAAE 332
+ E
Sbjct: 721 KAKSPVKE 728
Score = 42.4 bits (98), Expect = 6e-04
Identities = 42/159 (26%), Positives = 67/159 (42%), Gaps = 13/159 (8%)
Query: 7 KTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPA 66
K K E A E+P E+ V + +A ++ KV A A+ KE+ +
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKK----KVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Query: 67 ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEA 126
A KE A + P AEK E AAPE + KE A+ +P + A+ +
Sbjct: 929 AKKEPDDAKAKEPSKP--AEKKE----AAPEKKDT---KEEKAKKPEEKPKTEAKAKEDD 979
Query: 127 ASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFK 165
+ + S PKAE S +++ K ++ + K+ K
Sbjct: 980 KTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 79.0 bits (193), Expect = 6e-15
Identities = 95/359 (26%), Positives = 134/359 (37%), Gaps = 63/359 (17%)
Query: 21 EAAVASSPSKA---NGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGS 77
EA + P++ + +E+ V++ + P +AE EE A P A+K
Sbjct: 323 EAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLG 382
Query: 78 GAASPSAAE-------------------KGEPAAAAAPEAGASPVEKEAPAEGEAAEPGS 118
SPSA + K EP A P+ E EA E
Sbjct: 383 EIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQL 442
Query: 119 PTAAEGEAASAASSTSSPKAED-------------GATPSPSNETPKKKKKRFSFKKSFK 165
TA E A A + SP ++ AT P++ETP + +
Sbjct: 443 STAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEAR---------- 492
Query: 166 LSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGE---QAAAPGEEA 222
S S + + +EA E ++P AE E A A A + E +A +P E
Sbjct: 493 -SPLSEETSAEEAH--AEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEE 549
Query: 223 AAGEEGAAGGDPQEAKPQEAAVAPEK--PPASDETKAAEEPSKVEEKKAEEAGASAAACE 280
+ EE A AK AP + PP+ +ET A E + ++ A EA A A E
Sbjct: 550 TSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAE 609
Query: 281 APSAAGPGAPPEQEAAPAEE--------PAAAAASSACAAPSQEAQPECSPEAPPAEAA 331
AP E + PAEE PA A + P++EA E P PPAE A
Sbjct: 610 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP--PPAEEA 666
Score = 77.0 bits (188), Expect = 2e-14
Identities = 97/350 (27%), Positives = 139/350 (39%), Gaps = 66/350 (18%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEE---LQANGSAPAADKEEPAAA 75
P E A+ +P+K + + D P E +EE LQ + + +E P
Sbjct: 400 PAEGALEEAPAKV--EPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEF 457
Query: 76 GSGAASPSAAEKG----------EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
S + AE+ EP A P SP+ +E AE AE SP A E
Sbjct: 458 QSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETT 517
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
A A++ A + +P++ETP + + S S + + +EA E +
Sbjct: 518 AEEASAEIQLLAAIE----APADETPAEAQ-----------SPLSEETSAEEAP--AEVQ 560
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAA----AGEEGAAGGDPQEAKPQE 241
+P+A+G E A E SGE+ A AA A E +A P E +P
Sbjct: 561 SPSAKGVSIEEA------PLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPP 614
Query: 242 AAVAPEK--PPASDETKAA-------EEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPE 292
A AP + PP ++E A E P++V+ AEEA A A A PP
Sbjct: 615 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 674
Query: 293 QEAAPAE-----------EPAAAAASSACA--APSQEAQPECSPEAPPAE 329
E APAE E AA S A P++EA + +PPA+
Sbjct: 675 AEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVD--KHSPPAD 722
Score = 61.2 bits (147), Expect = 1e-09
Identities = 93/348 (26%), Positives = 130/348 (37%), Gaps = 53/348 (15%)
Query: 34 QENGHVKVNGDAS---PAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEP 90
QE VK A P+ + AK + A A + PA PS E +
Sbjct: 244 QEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDA 303
Query: 91 AAAAAPEAGASPVE----KEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSP 146
AA A + V+ +EAP AE P+A E + + P AE+ + P
Sbjct: 304 EAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEP 363
Query: 147 SNET-PKKKKKRFSFKKSFKLSGFSFKKNKKEA----GEGGEAEAPAA------------ 189
E P +K S + ++ S +K E EG EAPA
Sbjct: 364 PAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLAD 423
Query: 190 -------EGGKDEAAGGAAAAAAEAGAASGE---QAAAP----GEEAAAGEEGAAGGDPQ 235
E ++EA + A E A Q+ P EEA+A + A +P
Sbjct: 424 VQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEP- 482
Query: 236 EAKPQEAAVAPEKPPASDETKAAEEPSKV-----EEKKAEEAGASA---AACEAPSAAGP 287
P + A + P S+ET A E ++V EE AEEA A AA EAP+ P
Sbjct: 483 ---PADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETP 539
Query: 288 G---APPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
+P +E + E PA + SA +EA E P + AE
Sbjct: 540 AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAE 587
Score = 43.9 bits (102), Expect = 2e-04
Identities = 56/249 (22%), Positives = 87/249 (34%), Gaps = 19/249 (7%)
Query: 3 AQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANG 62
A+ ++ +A E P E V S +K E +++ + A +Q
Sbjct: 540 AEAQSPLSEETSAEEAPAE--VQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLA 597
Query: 63 SAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAA 122
+ A+ +E PA A + AE P A AP P +EAPAE + P A
Sbjct: 598 ATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQ------PPPA 651
Query: 123 EGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGG 182
E EA + + +A P P+ E P + +S ++
Sbjct: 652 E-EAPAEVQPPPAEEAPAEVQPPPAEEAPAE-------VQSLPAEETPIEETLAAVHSPP 703
Query: 183 EAEAPAAEGGKDEAAGGAAAAAAE---AGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP 239
+ PA E D+ + A E G AS E + P E+ E + P
Sbjct: 704 ADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSP 763
Query: 240 QEAAVAPEK 248
Q A + K
Sbjct: 764 QVAGIPAVK 772
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 75.1 bits (183), Expect = 8e-14
Identities = 80/234 (34%), Positives = 103/234 (44%), Gaps = 47/234 (20%)
Query: 104 EKEAPAEGEAAEP-GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKK 162
EK+ AEG A E G+P +E +AA+ + K + P + K ++
Sbjct: 21 EKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEK------PDQDAEGKAEE------ 68
Query: 163 SFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEA 222
K+ +K+A E EAP AE K E GAA A AE A ++ AAPG
Sbjct: 69 ---------KEGEKDAAAAKE-EAPKAEPEKTE---GAAEAKAEPPKAPEQEQAAPGP-- 113
Query: 223 AAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVE-EKKAEEAGASAAACEA 281
AAGG+ +A AA A PA A EEPSK E E K EA A+ AA E
Sbjct: 114 ------AAGGEAPKAAEAAAAPAESAAPA-----AGEEPSKEEGEPKKTEAPAAPAAQET 162
Query: 282 PSAAGPGA---PPEQEAAPA--EEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330
S P + P EAAP+ E PAA A S + P + + E P EA
Sbjct: 163 KSDGAPASDSKPGSSEAAPSSKETPAATEAPS--STPKAQGPAASAEEPKPVEA 214
Score = 68.6 bits (166), Expect = 8e-12
Identities = 79/269 (29%), Positives = 112/269 (41%), Gaps = 51/269 (18%)
Query: 1 MGAQFSKTA----AKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGA-K 55
MG + SK E A E+ +A A++ + +E+ + A PA A+ G K
Sbjct: 1 MGGKLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKES---EPQAAAEPAEAKEGKEK 57
Query: 56 EELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAE 115
+ A G A + E+ AAA A + EK E AA A E +P E+E A G AA
Sbjct: 58 PDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAP-EQEQAAPGPAAG 116
Query: 116 PGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNK 175
+P AAE AA A S ++P A G PS
Sbjct: 117 GEAPKAAEAAAAPAES--AAPAA--GEEPS------------------------------ 142
Query: 176 KEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQ 235
KE GE + EAPAA ++ + GA A+ ++ G++ AAP + A P+
Sbjct: 143 KEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSE----AAPSSKETPAATEAPSSTPK 198
Query: 236 EAKPQEAAVAP---EKPPA-SDETKAAEE 260
P +A P E P A SD+T +E
Sbjct: 199 AQGPAASAEEPKPVEAPAANSDQTVTVKE 227
Score = 65.1 bits (157), Expect = 8e-11
Identities = 64/189 (33%), Positives = 84/189 (44%), Gaps = 28/189 (14%)
Query: 161 KKSFKLSGFSFKKNK-KEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEA--GAASGEQAAA 217
K S K G++ K KE + E A EG E+ AAA AEA G +Q A
Sbjct: 4 KLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAE 63
Query: 218 PGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAA 277
E GE+ AA AK + PEK + E KA EP K E++ + A AA
Sbjct: 64 GKAEEKEGEKDAAA-----AKEEAPKAEPEKTEGAAEAKA--EPPKAPEQE-QAAPGPAA 115
Query: 278 ACEAPSAAGPGAPPEQEAAPA---------------EEPAAAAA--SSACAAPSQEAQPE 320
EAP AA A P + AAPA E PAA AA + + AP+ +++P
Sbjct: 116 GGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPG 175
Query: 321 CSPEAPPAE 329
S AP ++
Sbjct: 176 SSEAAPSSK 184
Score = 55.1 bits (131), Expect = 9e-08
Identities = 52/161 (32%), Positives = 65/161 (40%), Gaps = 29/161 (18%)
Query: 199 GAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAA--------------- 243
G + + G ++ A ++ A G G P+E++PQ AA
Sbjct: 2 GGKLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQD 61
Query: 244 ---VAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSA-----AGPGAPPEQEA 295
A EK D A EE K E +K E GA+ A E P A A PG EA
Sbjct: 62 AEGKAEEKEGEKDAAAAKEEAPKAEPEKTE--GAAEAKAEPPKAPEQEQAAPGPAAGGEA 119
Query: 296 APAEEPAAAAASSACAA----PSQEAQPECSPEAPPAEAAE 332
A E AAA A SA A PS+E EAP A AA+
Sbjct: 120 PKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQ 160
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 73.9 bits (180), Expect = 2e-13
Identities = 93/369 (25%), Positives = 137/369 (37%), Gaps = 46/369 (12%)
Query: 10 AKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKE---ELQANGS--- 63
++G A E G+A A ++ ++ + G+A P + + E E+Q
Sbjct: 1848 SEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAE 1907
Query: 64 APAADKE-EPAAAGSGAASPSAAEKGEPAAAAAPEA--------GASPVEKEAPAEGEAA 114
AP A+KE +P A ++ E A A EA G + E E EA
Sbjct: 1908 APEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAE 1967
Query: 115 EPGSPTA--------------AEGEAASAASSTSSPKAEDGATPSPSNETPK----KKKK 156
E P + AEGEA + +P+AE + P+ + +
Sbjct: 1968 EEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQP 2027
Query: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA 216
+ +++ ++ G + K E EAP AE EA G A EA S + A
Sbjct: 2028 KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDA 2087
Query: 217 APGE-EAAAGEEGAAGGDPQ-EAKPQEAAVAPE-KPPASDETKAAEEPSKVEEKKAEEAG 273
E EA EG + + EA+ E APE + A E++ E P E + E G
Sbjct: 2088 QEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEG 2147
Query: 274 ASAAACEA---PSAAG-------PGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSP 323
A E P + G A PE E A E A + + EA+ E P
Sbjct: 2148 VEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQP 2207
Query: 324 EAPPAEAAE 332
E EA E
Sbjct: 2208 ELEGVEAPE 2216
Score = 72.0 bits (175), Expect = 7e-13
Identities = 90/351 (25%), Positives = 129/351 (36%), Gaps = 46/351 (13%)
Query: 11 KGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE 70
K E G+A K + E G+A + E GS + +
Sbjct: 1756 KDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQ 1815
Query: 71 EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEK--EAP-AEGEAAEPGSPTAAEGEAA 127
AAAG G P ++ E A E A P + EAP AEG+A E AEGEA
Sbjct: 1816 GEAAAG-GDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQE------AEGEA- 1867
Query: 128 SAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKL----SGFSFKKNKKEA-GEGG 182
P++ED P E + + + + +++ G + +KEA E
Sbjct: 1868 -------QPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETE 1920
Query: 183 EAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQ------- 235
EA EG + + GA A AE A E P E +E P+
Sbjct: 1921 SVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEAL 1980
Query: 236 --EAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAE--------EAGASAAACEAPSAA 285
E + QEA E P S++ +A E +++E + E EA + EA
Sbjct: 1981 EVEVETQEA--EGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVE 2038
Query: 286 GPGAPPEQEAAP----AEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
G E +A P E P A + QEA+ E PE+ +A E
Sbjct: 2039 GETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQE 2089
Score = 71.6 bits (174), Expect = 9e-13
Identities = 83/325 (25%), Positives = 116/325 (35%), Gaps = 23/325 (7%)
Query: 15 AAERPGEAAVASSPSKANGQENGHVKVNGDASPAAA---ESGAKEELQANGS-APAADKE 70
A E GE S ++A E + G P + A+EE Q A + E
Sbjct: 1924 ALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVE 1983
Query: 71 EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAA 130
G A P + + APEA E E A+ E+ + +EGE A
Sbjct: 1984 VETQEAEGEAQPESED------VEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEV 2037
Query: 131 SSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAE 190
+ D S E P+ +++ + + G + + E + +A AE
Sbjct: 2038 EGETQKTEGDAQPESDGVEAPEAEEE------AQEAEGEVQEAEGEAHPESEDVDAQEAE 2091
Query: 191 GGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQ---EAKPQEAAVAPE 247
G + G A AE A E AP E A E P+ EA+P+ V E
Sbjct: 2092 GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGV--E 2149
Query: 248 KPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAAS 307
A E + E + +E + EEA EAP A G A PE E A E A
Sbjct: 2150 AQDAEGEAQPESEGIEAQEAE-EEAQPELEGVEAPEAEGE-AQPESEGIEAPEAEGEAQP 2207
Query: 308 SACAAPSQEAQPECSPEAPPAEAAE 332
+ EA+ E PE E E
Sbjct: 2208 ELEGVEAPEAEEEAQPEPEGVETPE 2232
Score = 63.2 bits (152), Expect = 3e-10
Identities = 80/294 (27%), Positives = 106/294 (36%), Gaps = 24/294 (8%)
Query: 10 AKGEAAAERPG-EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAAD 68
A+ EA E G EA S +A E K GDA P ES E +A A A+
Sbjct: 2012 AEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP---ESDGVEAPEAEEEAQEAE 2068
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAAS 128
E A G + E A PE+ EA E + AE EGEA
Sbjct: 2069 GEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAP-EAEGEAQKAEGIEAPETEGEAQP 2127
Query: 129 AASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEA-EAP 187
+ +P+AE A P E+ + + + + G ++ ++EA E EAP
Sbjct: 2128 ESEGIEAPEAEGEAQP----ESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP 2183
Query: 188 AAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPE 247
AEG + G A AE A Q G EA EE EA+P+ V E
Sbjct: 2184 EAEGEAQPESEGIEAPEAEGEA----QPELEGVEAPEAEE--------EAQPEPEGV--E 2229
Query: 248 KPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEP 301
P A E + E EKK + ++ PE P P
Sbjct: 2230 TPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSP 2283
Score = 60.1 bits (144), Expect = 3e-09
Identities = 93/373 (24%), Positives = 132/373 (35%), Gaps = 52/373 (13%)
Query: 1 MGAQFSKTAAKGEAAAERPGEAAVAS-----SPSKANGQENGHVKVNGDASPAAAES-GA 54
+G+Q + A E P EA V SP G G +K D G
Sbjct: 1643 LGSQLGEEAEGEEFC---PCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGE 1699
Query: 55 KEELQANGSAPAADKEEPAAA----------GSGAASPSAAEKGEPAAAAAPEAGASPVE 104
+ +A AP +P + G G + ++GE G+ +
Sbjct: 1700 HTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGE------GSQRLN 1753
Query: 105 KEA-PAEGEAAEPGSPTAAEGEAASAASSTSSPKAE---DGATPSPSNETPKKKKKRFSF 160
++ P GEA EG+ ++ +S S E +G S ET +
Sbjct: 1754 RDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDN 1813
Query: 161 KKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGE 220
+ +G + + EG EAP AEG + G A AE A E A P
Sbjct: 1814 LQGEAAAGGDQDPGQSDGAEG--IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPES 1871
Query: 221 EAAAGEEGAAGGDPQ-----------EAKPQ-EAAVAPE-KPPASDETKAAEEPSKVEEK 267
E E P+ E +P+ E A APE + A ET++ E E
Sbjct: 1872 EDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED 1931
Query: 268 KAEEAGASAAACE--APSAAGPGAPPEQ--EAAPAEEPAAAAASSACA----APSQEAQP 319
+ E GA A E A A G P + E+ AEE A + A +QEA+
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 320 ECSPEAPPAEAAE 332
E PE+ EA E
Sbjct: 1992 EAQPESEDVEAPE 2004
Score = 59.7 bits (143), Expect = 4e-09
Identities = 70/263 (26%), Positives = 108/263 (41%), Gaps = 34/263 (12%)
Query: 10 AKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADK 69
++G A E GEA S +A E + AE A+ EL+ + A +
Sbjct: 2129 SEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGE 2188
Query: 70 EEPAAAG--------------SGAASPSAAEKG--EPAAAAAPEA-GASPVEKEAPAEGE 112
+P + G G +P A E+ EP PEA G + E E +GE
Sbjct: 2189 AQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGE 2248
Query: 113 AAEPGSPTAAEGEAAS-AASSTSSPKAEDGAT--PSPSNETPKKKKKRFSFKKSFKLS-- 167
+ GSP + G+ S AS +SSP ED T PSP +TP ++ + S + S
Sbjct: 2249 --KKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSW 2306
Query: 168 GFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAG-- 225
G ++K+ + G+ +P D + G A +A E + + EEA G
Sbjct: 2307 GNCWQKDSENDHVLGDTRSP------DAKSTGTPHAERKATRMYPESSTSEQEEAPLGSR 2360
Query: 226 --EEGAAGGDPQEAKPQEAAVAP 246
E+GA+ G + ++AP
Sbjct: 2361 TPEQGASEGYDLQEDQALGSLAP 2383
Score = 42.7 bits (99), Expect = 4e-04
Identities = 43/160 (26%), Positives = 62/160 (38%), Gaps = 21/160 (13%)
Query: 168 GFSFKKNKKEAGEGGEAEAPAAE-----GGKDEAAGGAAAAAAEAGAASGEQAAAPGE-- 220
G ++ K+ GEG + E E GG+ G + G G Q A E
Sbjct: 1335 GVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGL 1394
Query: 221 -EAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAAC 279
E EEG+ G QE + A +S + K ++E V+E++A A ASA C
Sbjct: 1395 KEEGLPEEGSVHG-------QELSEA-----SSPDGKGSQEDDPVQEEEAGRASASAEPC 1442
Query: 280 EAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQP 319
A P PP + + A+ S + P E P
Sbjct: 1443 PAEGTEEPTEPP-SHLSETDPSASERQSGSQLEPGLEKPP 1481
Score = 42.4 bits (98), Expect = 6e-04
Identities = 63/340 (18%), Positives = 112/340 (32%), Gaps = 42/340 (12%)
Query: 12 GEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKE-----ELQANGSAPA 66
G A R + ++SP+ + G G + P E G ++ A A
Sbjct: 439 GHGTAGRERCSQDSASPASSTGLPEGS-EPESSCCPRTPEDGVDSASPSAQIGAERKAGG 497
Query: 67 ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPA--EGEAAEPGSPTAAEG 124
+ E+P GA + G A E GAS + EG + G P G
Sbjct: 498 SLGEDPGLCIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGCPG 557
Query: 125 EAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEA 184
+A + S + + D A+P+ S LS + E G
Sbjct: 558 KARAETSQQEASEGGDPASPALS------------------LSSLRSDDLQAETQGQGTE 599
Query: 185 EAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAV 244
+A A ++ G + + GA+S ++ A + P V
Sbjct: 600 QATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRV 659
Query: 245 APEKPPAS-----------DETKAAEEPSKVEEKKAEEAG-----ASAAACEAPSAAGPG 288
AP P D + + P E ++A + G + +++ A+G
Sbjct: 660 APRGHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNL 719
Query: 289 APPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
PP + P+++ ++++ A + SP P+
Sbjct: 720 RPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPS 759
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/151 (24%), Positives = 59/151 (39%), Gaps = 13/151 (8%)
Query: 175 KKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASG---EQAAAPGEEAAAGE----E 227
++ GEG + E E K+ GG A E G E+ + G+E + +
Sbjct: 1360 EETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGK 1419
Query: 228 GAAGGDP-QEAKPQEAAVAPEKPPASDETKAAEEPSKVEE-----KKAEEAGASAAACEA 281
G+ DP QE + A+ + E PA + E PS + E + + E
Sbjct: 1420 GSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEK 1479
Query: 282 PSAAGPGAPPEQEAAPAEEPAAAAASSACAA 312
P A +A P + A ++S AC+A
Sbjct: 1480 PPGATMMGQEHTQAQPTQGAAERSSSVACSA 1510
Score = 37.7 bits (86), Expect = 0.014
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 12/157 (7%)
Query: 179 GEGGEAEAPAAEGGKDEAA---GGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQ 235
GEG + EA E K E G + G+Q EEA E GG+
Sbjct: 1312 GEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQE----EEAQLEEIEETGGEGL 1367
Query: 236 EAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEA 295
+ + + E P + +A EE K E E + EA S G G+ +
Sbjct: 1368 QEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPV 1427
Query: 296 APAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
E A+A++ C A E P PP+ +E
Sbjct: 1428 QEEEAGRASASAEPCPAEGTE-----EPTEPPSHLSE 1459
Score = 33.9 bits (76), Expect = 0.21
Identities = 59/308 (19%), Positives = 118/308 (38%), Gaps = 49/308 (15%)
Query: 45 ASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104
AS + + ++ Q + A+ P++ G G +P +G P + + SP++
Sbjct: 624 ASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAP----RGHPRHSHYRKDTHSPLD 679
Query: 105 KEA-------PAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKR 157
P A + GS G ++S + S + PS +
Sbjct: 680 SSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSAT 739
Query: 158 FS-FKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA 216
+ S +SG S N AG G+A G + + +++ + SG AA
Sbjct: 740 VTPAVHSDFVSGVS-PHNAPSAGWAGDA------GSRTCSPAPIPPHTSDSCSKSG--AA 790
Query: 217 APGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDE--TKAAEEPSK----------- 263
+ GEEA + ++ Q +P++ AV P + + T+ A+E +
Sbjct: 791 SLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCG 850
Query: 264 -----------VEEKKAEEAGASAAACEAPSAAGPGAPPEQ---EAAPAEEPAAAAASSA 309
++++ G++ ++ ++ +A GPG P++ + P P + +S
Sbjct: 851 RYCPTPPRGRPCPQRRSSSCGSTGSSHQS-TARGPGGSPQEGTRQPGPTPSPGPNSGASR 909
Query: 310 CAAPSQEA 317
++ SQ A
Sbjct: 910 RSSASQGA 917
Score = 33.5 bits (75), Expect = 0.27
Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 25/229 (10%)
Query: 59 QANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGS 118
+++ + A G G + + P + P +GAS + G
Sbjct: 866 RSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEE 925
Query: 119 PTAAEG------EAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSF- 171
T G E AS S +S P++ A + ++ +++ + + +G +
Sbjct: 926 KTLRSGGGPQGQEEASGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGG 985
Query: 172 -----------KKNKKEAGEGGEAEAPAAEG--GKDEAAGGAAAAAAEAGAASGE---QA 215
+ + GE +A + EG G+D GA +++ G SGE Q
Sbjct: 986 GLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQG 1045
Query: 216 AAP-GEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSK 263
AAP G A E GA P + A+ P + AS + A SK
Sbjct: 1046 AAPEGVSEAPAEAGADREAPAGCRVSLRAL-PGRVSASTQIMRALMGSK 1093
Score = 30.4 bits (67), Expect = 2.3
Identities = 43/158 (27%), Positives = 52/158 (32%), Gaps = 17/158 (10%)
Query: 2 GAQFSKTA-AKGEAAAERPGEAAVASSPSKANGQENG----HVKVN--GDASPAAAESGA 54
G Q +T +GE E + QE G VK G A E G
Sbjct: 1335 GVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGL 1394
Query: 55 KEE-LQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKE-APAEGE 112
KEE L GS + E A+SP E EAG + E PAEG
Sbjct: 1395 KEEGLPEEGSVHGQELSE-------ASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEG- 1446
Query: 113 AAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNET 150
EP P + E +AS S + P T
Sbjct: 1447 TEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGAT 1484
Score = 30.0 bits (66), Expect = 3.0
Identities = 34/140 (24%), Positives = 47/140 (33%), Gaps = 2/140 (1%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE-EPAAAGSGA 79
E A ++ + G V D S A+ Q+ P D E E A GS
Sbjct: 974 ELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSD 1033
Query: 80 ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAE 139
P + E G P AA +P E A E A S A G +++ +
Sbjct: 1034 TGPQSGE-GVPQGAAPEGVSEAPAEAGADREAPAGCRVSLRALPGRVSASTQIMRALMGS 1092
Query: 140 DGATPSPSNETPKKKKKRFS 159
PS E + +R S
Sbjct: 1093 KQGRPSSVPEVSRPMARRLS 1112
>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
[Homo sapiens]
Length = 1008
Score = 73.2 bits (178), Expect = 3e-13
Identities = 92/337 (27%), Positives = 126/337 (37%), Gaps = 24/337 (7%)
Query: 10 AKGEAAAERPGEA------AVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQAN-G 62
+KG+A A G+ V S+P K +G V A G L G
Sbjct: 555 SKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKG 614
Query: 63 SAPAADKEEPAAAGSGAASPSAAEK------GEPAAAAAPEAGASPVEKEAPAEGEAAEP 116
S K +P A SG A P + K G+ AAA EAGA ++KE P E +P
Sbjct: 615 SPVTTTKADPRA--SGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDP 672
Query: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKK 176
GS AE A+ S KA+ + PS E+P K + K S S + ++K
Sbjct: 673 GSCRKAEPLASGKGEPVSLGKAD--SAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRK 730
Query: 177 EAGEGGEAEAPAAEGGKDE--AAGGAAAAAAEAGAASGEQAAA---PGEEAAAGEEGAAG 231
G E G+ E A ++ A+ G E A A P EAAA G
Sbjct: 731 ALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRT 790
Query: 232 GDPQEAKPQEAAVAPEKPPASDETKAAEEP--SKVEEKKAEEAGASAAACEAPSAAGPGA 289
D P A AP P T+A + S + + GA +A +A +
Sbjct: 791 RDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPS 850
Query: 290 PPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAP 326
PP + A + AA + + A Q P P
Sbjct: 851 PPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAFP 887
Score = 61.2 bits (147), Expect = 1e-09
Identities = 84/384 (21%), Positives = 130/384 (33%), Gaps = 89/384 (23%)
Query: 12 GEAAAERPGEAAVASS----PSKANGQENGHVKVN----GDASPAAAESGAKEELQANGS 63
G+A PG+ SS P A ++ KVN G +P ++ G L G
Sbjct: 446 GKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGP 505
Query: 64 APAADKEEPAAAG--------------SGAASPSAAEKGEPAAAAAPEAGASPVEKEAPA 109
P+A K EPA G SG A+P+A+ K EP A + + P+
Sbjct: 506 -PSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPS 564
Query: 110 -EGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSG 168
+G++ G + G+ S P + A P + ++ S + K
Sbjct: 565 GQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADP 624
Query: 169 FSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGE-----------QAAA 217
+ K + ++G E + P EG GA E AS + A+
Sbjct: 625 RASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASG 684
Query: 218 PGEEAAAGEEGAA-------------------------------------GGDPQEAKPQ 240
GE + G+ +A P+ A+
Sbjct: 685 KGEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGS 744
Query: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPG--------APPE 292
E V P+ P S + E S + +K E AGA + C +A PG P
Sbjct: 745 EGRVEPKAEPVS-----STEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPS 799
Query: 293 QEAA----PAEEPAAAAASSACAA 312
EA+ P E+ A + AC +
Sbjct: 800 WEASAPPPPREDAGTQAGAQACVS 823
Score = 55.1 bits (131), Expect = 9e-08
Identities = 93/375 (24%), Positives = 133/375 (35%), Gaps = 60/375 (16%)
Query: 6 SKTAAKGEAAAERPGEAAVA----SSPSKANGQENGHVKVNGDASPAAAESGAKEELQAN 61
++T G+ A PGEA +P + + G + A P A+ G L
Sbjct: 638 AETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCR---KAEPLASGKGEPVSLGKA 694
Query: 62 GSAPAADKEEPAAAGSGAASPSAAEKGEPAAAA------APEAGASPVEKEAPAEGEA-- 113
SAP+ E P+ G P + EK +P++++ A + SP E +EG
Sbjct: 695 DSAPSRKTESPSL---GKVVPLSLEKTKPSSSSRQLDRKALGSARSP-EGARGSEGRVEP 750
Query: 114 -AEPGSPTAAEG------EAASA--------ASSTSSPKAEDGATPSPSNET---PKKKK 155
AEP S T A EAA A A+ P+ D T +PS E P ++
Sbjct: 751 KAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPRE 810
Query: 156 KRFSFKKSFKLSGFSFKKNKKEAGEGGEA----EAPAA-------EGGKDEAAGGAAAAA 204
+ + + + G GG A AP A + G + G A +
Sbjct: 811 DAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAETRS 870
Query: 205 AEAGAASGEQAAAPGEEAAAGEEG----AAGGDPQEAKPQEAAVAPEKPPASDETKAAEE 260
G + + AA P G AA P+ A+P EK + AA E
Sbjct: 871 VATGPMTPQAAAPPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAME 930
Query: 261 PS-------KVEEKKAEEAGASAAACEAPSA-AGPGAPPEQEAAPAEEPAAAAASSACAA 312
K E++ EE G A P+A AGPG AP + A A
Sbjct: 931 VEVLGMAIQKHLERQIEEHGRQGAPAPPPAARAGPGRSGSVRTAPPDGAAKRPPGLFRAL 990
Query: 313 PSQEAQPECSPEAPP 327
+P C A P
Sbjct: 991 LQSVRRPRCCSRAGP 1005
Score = 32.7 bits (73), Expect = 0.46
Identities = 61/298 (20%), Positives = 105/298 (35%), Gaps = 87/298 (29%)
Query: 17 ERPGEAAVASSPSKANGQENGHVKVNGDASPAAA-------------------ESGAKEE 57
++ A +P ++ G E+ H +G A+ ES +KE
Sbjct: 50 QKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKET 109
Query: 58 LQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAA--------------AAPEAGASPV 103
L+A+G A+ P A SG P ++ K EP ++ ++ +A ++ +
Sbjct: 110 LEAHG---ASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSI 166
Query: 104 EKEAPAEGEAAEPGSPTAAEGE-------------------------------AASAASS 132
KE P A+P AE E S+ +
Sbjct: 167 GKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTY 226
Query: 133 TSSPKAEDGAT-----PSPSNET----PKKKKKRFSFKK----SFKLSGFSFKK------ 173
T SP+ ED + P S++ P+K++ R+S K+ S K++ S +K
Sbjct: 227 TVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLS 286
Query: 174 NKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAG 231
K++ G G+A+ P D A+ G G + G G+ G
Sbjct: 287 GKRDPGPSGKAD-PMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLG 343
>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
Length = 621
Score = 72.0 bits (175), Expect = 7e-13
Identities = 103/381 (27%), Positives = 140/381 (36%), Gaps = 75/381 (19%)
Query: 10 AKGEAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSAPAAD 68
AK AAA AA ASS S A G + +NG S + + GS A
Sbjct: 215 AKDLAAAAAAAAAAAASSSSSAPAAAPPGAIPLNGFLSYVQSRGLELKPGGCGGSGDAFG 274
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAA-PEAGASP-VEKEAPAEGEA---------AEPG 117
A GS P+A G P AA+ P+ +SP +E P+ EA G
Sbjct: 275 AAAMLAKGSWPPHPAAPSGGRPRGAASPPDLASSPRCPREPPSLAEAVYSVYRERSGVAG 334
Query: 118 SPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKE 177
S AA AA+AASS SSP P E+ ++ SF S LS F+ +
Sbjct: 335 SRRAAAATAAAAASSCSSP------APCSPPESWGRQSTASSFVDS-SLSAFALLPLQGG 387
Query: 178 AGEGGEAEA-------PAAEGGKDEAAGG--------------------------AAAAA 204
GG+AE P E G E G A A
Sbjct: 388 RDRGGDAEGASCSWQRPPGERGSQEIPRGELDLSMTNLRGAEGSMRGARREPEEPEGAVA 447
Query: 205 AEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPP--------ASDETK 256
A A G + G AA +G A P +PE PP +S K
Sbjct: 448 ARAARGQGGRLPRTGRYAALRRRSTSGLPDYRAPP-----SPEPPPSPGSADPDSSPLAK 502
Query: 257 AA--EEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEP-----AAAAASSA 309
AA P ++E + ++ + PS++ G P +EA + E A SA
Sbjct: 503 AASPSPPLRLEGSPPTRRDSGSSQSDDPSSSNKGYTPLREAGTSTESVLDAVAGQTRDSA 562
Query: 310 CAAP---SQEAQPECSPEAPP 327
AAP ++++ PE + + PP
Sbjct: 563 VAAPVLGAEQSSPEGASQEPP 583
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 70.9 bits (172), Expect = 2e-12
Identities = 90/320 (28%), Positives = 127/320 (39%), Gaps = 32/320 (10%)
Query: 15 AAERPG--EAAVASSPSKANGQENGHVKVNGDAS--PAA--AESGAKEELQANGSAPAAD 68
AA +PG A A S S+ + V G S PA A S + +E A +APA
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
Query: 69 KE-EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAA 127
K + G A P A +P + S E+EAPA + S + AA
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
Query: 128 SAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
SA + + K GATP+P P K S K+ K S ++ E E E P
Sbjct: 304 SAPAKGTPGK---GATPAP----PGKAGAVASQTKAGKPEEDS--ESSSEESSDSEEETP 354
Query: 188 AAEG-------GKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
AA+ GK G A+A A E S + AAP A G+ G A Q K +
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAP---APPGKTGPAVAKAQAGKRE 407
Query: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 300
E + + + S+E A+ +K K + ASA A E+P APP + A +
Sbjct: 408 EDSQSSSEESDSEEEAPAQ--AKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQ 465
Query: 301 PAAAAASSACAAPSQEAQPE 320
+ S+E+ +
Sbjct: 466 VQVGKQEEDSRSSSEESDSD 485
Score = 61.2 bits (147), Expect = 1e-09
Identities = 76/338 (22%), Positives = 116/338 (34%), Gaps = 29/338 (8%)
Query: 15 AAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAES--GAKEELQANGSAPAADKEEP 72
A+E+ + AS+P+K + G A A+++ G EE + S ++D EE
Sbjct: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
Query: 73 AAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG---EAASA 129
A A+ K AA+ A SP + APA P A G E + +
Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412
Query: 130 ASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKK-------EAGEGG 182
+S S + E A PS + P+ + K+S + K + G+
Sbjct: 413 SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
Query: 183 EAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEA 242
E ++E + AA AA+ P G G G K
Sbjct: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK---- 528
Query: 243 AVAPEKPPAS------DETKAAEEPSKVEEKKAEEAGASAAA------CEAPSAAGPGAP 290
V P P A D ++EE S + + A A A +A + P
Sbjct: 529 -VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG 587
Query: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
P Q+A P A + S+E+ E PA
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/306 (24%), Positives = 117/306 (38%), Gaps = 49/306 (16%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEE-PAAAGSGA 79
+A SSP+K Q+ G V V A S + EE S+ +AD EE PAA +
Sbjct: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE-----SSDSADSEEAPAAMTAAQ 631
Query: 80 ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAE 139
A P A P+ A P + A + A T A +A +A S S A
Sbjct: 632 AKP---------ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
Query: 140 DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGG 199
G T P+ ++ + +E+ E A G+ ++ G
Sbjct: 683 AGGTQRPAEDS----------------------SSSEESDSEEEKTGLAVTVGQAKSVG- 719
Query: 200 AAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259
+ AAS + G+ A G G + K ++ + SD +AA
Sbjct: 720 ---KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 260 EPSKVEEK-KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQ 318
P++V+ K +A A+ AA APSA G + P + AAA + +PS+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAP-------GKVVTAAAQAKQRSPSKVKP 829
Query: 319 PECSPE 324
P +P+
Sbjct: 830 PVRNPQ 835
Score = 59.7 bits (143), Expect = 4e-09
Identities = 71/340 (20%), Positives = 127/340 (37%), Gaps = 27/340 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAK----EELQAN 61
S K +A E+ G+ S P A G+ ++ ++G + +AE A E +
Sbjct: 119 SSMKEKAKAETEKAGKTG-NSMPHPATGKTVANL-LSGKSPRKSAEPSANTTLVSETEEE 176
Query: 62 GSAPA-ADKEEPAAAGSGAASPSAAE----------KGEPAAAAAPEAGASPVEKEAPAE 110
GS PA +P +G A S+ + +G+P+ A +S KE+PA
Sbjct: 177 GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 111 GEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
A PG G+ + P A+ P +E+ ++ + S + +
Sbjct: 237 KAAPAPGKV----GDVTPQVKGGALPPAKRAKKPEEESESSEEGSE------SEEEAPAG 286
Query: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAA 230
+ K + + + A +A G A +AGA + + A EE + +
Sbjct: 287 TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
Query: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAP 290
+E +A + + + + AA P+K +K A + A G
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406
Query: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330
E + +EE + + A A PS +A + AP E+
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Score = 59.3 bits (142), Expect = 5e-09
Identities = 73/336 (21%), Positives = 121/336 (36%), Gaps = 20/336 (5%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
S A + P +A A+SP+ ++ G + + S ++ ES ++EE G A
Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE--KTGLAV 710
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
+ + G + S KG AP + E E + E +
Sbjct: 711 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 770
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
+ AA+S + K T + +N + S K + G K A + +
Sbjct: 771 SEEAAASPAQVKTSVKKTQAKANPAAARAP---SAKGTISAPG----KVVTAAAQAKQRS 823
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAA-- 243
+ A A S +A A +A G E +G +E+ +E A
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 244 VAPEKPPA-SDETKAAEEPSKVEEKKAE------EAGASAAACEAPSAAGPGAPPEQEAA 296
+A KP + + +AA P+K +K + G SAA +A G+ E+ +
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDSGSSSEESDS 941
Query: 297 PAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
E PAA ++ P P SP P A A+
Sbjct: 942 DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
Score = 57.0 bits (136), Expect = 2e-08
Identities = 77/323 (23%), Positives = 120/323 (37%), Gaps = 35/323 (10%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78
PG+ + KA QE+ S AA S A+ + + A+ PAAA +
Sbjct: 744 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN---PAAARAP 800
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGE------AAEPGSPTAAEGEAASAASS 132
+A + + G+ AAA SP + + P A P S + A+AA +
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 860
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
+ P+ + G S+E ++ K SG K ++ A E+P +G
Sbjct: 861 QTGPEEDSG-----SSEEESDSEEEAETLAQVKPSG---KTHQIRAALAPAKESP-RKGA 911
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPAS 252
G +AA+AG + ++ E + GE AA Q KP V P + PA
Sbjct: 912 APTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAG 970
Query: 253 D-----ETKAAEEPSKVEEKKAEEAGASAAACE--------APSAAGPGAPPEQEAAPAE 299
+ +AA P K +A E+ A +++ E A PG P
Sbjct: 971 PAATPAQAQAASTPRKA---RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 1027
Query: 300 EPAAAAASSACAAPSQEAQPECS 322
P A +S A S + S
Sbjct: 1028 HPRIAPKASMAGASSSKESSRIS 1050
Score = 55.8 bits (133), Expect = 5e-08
Identities = 82/328 (25%), Positives = 127/328 (38%), Gaps = 25/328 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
+K A K E +E E + S +A VK + A S + G+ P
Sbjct: 260 AKRAKKPEEESESSEEGS--ESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
A P AG+ AS + A K E + ++ E +S E+E PA + +
Sbjct: 318 AP----PGKAGA-VASQTKAGKPEEDSESSSEE-SSDSEEETPAAKALLQAKASGKTSQV 371
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
A++A + SP+ GA P+P +T K + K+ S + + +E EA
Sbjct: 372 GAASAPAKESPR--KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-----EAP 424
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVA 245
A A GK A+A A E S + AAP A + G A Q K +E + +
Sbjct: 425 AQAKPSGKAPQVRAASAPAKE----SPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRS 477
Query: 246 PEKPPASD-ETKAAEEPSKVEE-KKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAA 303
+ SD E AA ++V+ K+ + ++ P G G P + PA A
Sbjct: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 304 AAA-SSACAAPSQEAQPECSPEAPPAEA 330
+ S+E+ E P A A
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVA 565
Score = 50.8 bits (120), Expect = 2e-06
Identities = 68/307 (22%), Positives = 121/307 (39%), Gaps = 36/307 (11%)
Query: 40 KVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG 99
K DA+ A ++ + + + S+ ++EE A A + A+P A A +
Sbjct: 64 KAEEDAALQAKKTRVSDPISTSESS---EEEEEAEAETAKATPRLASTNSSVLGA--DLP 118
Query: 100 ASPVEKEAPAEGEAAEPGS--PTAAEGEAASAASSTSSPK--AEDGATPSPSNETPKKKK 155
+S EK +A + G+ P A G+ + S SP+ AE A + +ET ++
Sbjct: 119 SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG- 177
Query: 156 KRFSFKKSFKLSGFSFKKNKKEAGEG-GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQ 214
S G + K AG+ +E ++ + + G + A+ A+S
Sbjct: 178 -------SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
Query: 215 AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEK------- 267
+P +AA G G + K A +E++++EE S+ EE+
Sbjct: 231 KESPARKAAPAP-GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS 289
Query: 268 --KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEA 325
KA E A AP+ PG PA + A A+ ++ +PE E+
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGK--------GATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 326 PPAEAAE 332
E+++
Sbjct: 342 SSEESSD 348
Score = 49.7 bits (117), Expect = 4e-06
Identities = 69/299 (23%), Positives = 107/299 (35%), Gaps = 38/299 (12%)
Query: 13 EAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSA---PAAD 68
E AAE + VA S S +G G N AS A + + + + +A P
Sbjct: 1148 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1207
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA------------AEP 116
+E +G SP K E A+ P+ P + + +P
Sbjct: 1208 QEAKPQQAAGMLSPKTGGK-EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1266
Query: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKK----KKKRFSFKKSFKLSGFSFK 172
A+ +A+ T + E + E+ +K +K++ S + + S K
Sbjct: 1267 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1326
Query: 173 KNKKEAGEGGEAEAPA--------AEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAA 224
K K AGEGGEA + +D+A+G + S P EE
Sbjct: 1327 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1386
Query: 225 GEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPS 283
G GGD K ++ EK + K E+ +EKK + AS E+PS
Sbjct: 1387 GMGTVEGGDQSNPKSKK-----EKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPS 1436
Score = 35.4 bits (80), Expect = 0.071
Identities = 52/232 (22%), Positives = 88/232 (37%), Gaps = 31/232 (13%)
Query: 46 SPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEK 105
+P A+ +GA +++ + +E PA A A P + + G + + K
Sbjct: 1032 APKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPAT--SPQSTSVQAKGTNKLRK 1089
Query: 106 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFK 165
E + A ++ + E +S +SS S EDG P + K +
Sbjct: 1090 PKLPEVQQATKAPESSDDSEDSSDSSSGSE---EDGEGPQGA-------------KSAHT 1133
Query: 166 LSGFSFKKN----KKEAGEGGEAE--APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPG 219
L G + + ++ A E E + AP+ G A ++A A+ + ++P
Sbjct: 1134 LVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPS 1193
Query: 220 EEAAAGEEGAAGGDP---QEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKK 268
+ AA DP QEAKPQ+AA E + P K + K
Sbjct: 1194 VSSTL----AAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1241
Score = 33.1 bits (74), Expect = 0.35
Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 24/161 (14%)
Query: 29 SKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKG 88
S G E+ K++GD PAA +K+ K++ A G AS S +
Sbjct: 1300 SSRKGWESRKRKLSGD-QPAARTPRSKK------------KKKLGAGEGGEASVSPEKTS 1346
Query: 89 EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT-----------AAEGEAASAASSTSSPK 137
+ A AS KE +G G+ EG S S K
Sbjct: 1347 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKK 1406
Query: 138 AEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEA 178
D + KKK K+ S K S S KK KK A
Sbjct: 1407 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1447
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 70.9 bits (172), Expect = 2e-12
Identities = 90/320 (28%), Positives = 127/320 (39%), Gaps = 32/320 (10%)
Query: 15 AAERPG--EAAVASSPSKANGQENGHVKVNGDAS--PAA--AESGAKEELQANGSAPAAD 68
AA +PG A A S S+ + V G S PA A S + +E A +APA
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
Query: 69 KE-EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAA 127
K + G A P A +P + S E+EAPA + S + AA
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
Query: 128 SAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
SA + + K GATP+P P K S K+ K S ++ E E E P
Sbjct: 304 SAPAKGTPGK---GATPAP----PGKAGAVASQTKAGKPEEDS--ESSSEESSDSEEETP 354
Query: 188 AAEG-------GKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
AA+ GK G A+A A E S + AAP A G+ G A Q K +
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAP---APPGKTGPAVAKAQAGKRE 407
Query: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 300
E + + + S+E A+ +K K + ASA A E+P APP + A +
Sbjct: 408 EDSQSSSEESDSEEEAPAQ--AKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQ 465
Query: 301 PAAAAASSACAAPSQEAQPE 320
+ S+E+ +
Sbjct: 466 VQVGKQEEDSRSSSEESDSD 485
Score = 61.2 bits (147), Expect = 1e-09
Identities = 76/338 (22%), Positives = 116/338 (34%), Gaps = 29/338 (8%)
Query: 15 AAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAES--GAKEELQANGSAPAADKEEP 72
A+E+ + AS+P+K + G A A+++ G EE + S ++D EE
Sbjct: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
Query: 73 AAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG---EAASA 129
A A+ K AA+ A SP + APA P A G E + +
Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412
Query: 130 ASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKK-------EAGEGG 182
+S S + E A PS + P+ + K+S + K + G+
Sbjct: 413 SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
Query: 183 EAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEA 242
E ++E + AA AA+ P G G G K
Sbjct: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK---- 528
Query: 243 AVAPEKPPAS------DETKAAEEPSKVEEKKAEEAGASAAA------CEAPSAAGPGAP 290
V P P A D ++EE S + + A A A +A + P
Sbjct: 529 -VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG 587
Query: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
P Q+A P A + S+E+ E PA
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/306 (24%), Positives = 117/306 (38%), Gaps = 49/306 (16%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEE-PAAAGSGA 79
+A SSP+K Q+ G V V A S + EE S+ +AD EE PAA +
Sbjct: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE-----SSDSADSEEAPAAMTAAQ 631
Query: 80 ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAE 139
A P A P+ A P + A + A T A +A +A S S A
Sbjct: 632 AKP---------ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
Query: 140 DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGG 199
G T P+ ++ + +E+ E A G+ ++ G
Sbjct: 683 AGGTQRPAEDS----------------------SSSEESDSEEEKTGLAVTVGQAKSVG- 719
Query: 200 AAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259
+ AAS + G+ A G G + K ++ + SD +AA
Sbjct: 720 ---KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 260 EPSKVEEK-KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQ 318
P++V+ K +A A+ AA APSA G + P + AAA + +PS+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAP-------GKVVTAAAQAKQRSPSKVKP 829
Query: 319 PECSPE 324
P +P+
Sbjct: 830 PVRNPQ 835
Score = 59.7 bits (143), Expect = 4e-09
Identities = 71/340 (20%), Positives = 127/340 (37%), Gaps = 27/340 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAK----EELQAN 61
S K +A E+ G+ S P A G+ ++ ++G + +AE A E +
Sbjct: 119 SSMKEKAKAETEKAGKTG-NSMPHPATGKTVANL-LSGKSPRKSAEPSANTTLVSETEEE 176
Query: 62 GSAPA-ADKEEPAAAGSGAASPSAAE----------KGEPAAAAAPEAGASPVEKEAPAE 110
GS PA +P +G A S+ + +G+P+ A +S KE+PA
Sbjct: 177 GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 111 GEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
A PG G+ + P A+ P +E+ ++ + S + +
Sbjct: 237 KAAPAPGKV----GDVTPQVKGGALPPAKRAKKPEEESESSEEGSE------SEEEAPAG 286
Query: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAA 230
+ K + + + A +A G A +AGA + + A EE + +
Sbjct: 287 TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
Query: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAP 290
+E +A + + + + AA P+K +K A + A G
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406
Query: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330
E + +EE + + A A PS +A + AP E+
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Score = 59.3 bits (142), Expect = 5e-09
Identities = 73/336 (21%), Positives = 121/336 (36%), Gaps = 20/336 (5%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
S A + P +A A+SP+ ++ G + + S ++ ES ++EE G A
Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE--KTGLAV 710
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
+ + G + S KG AP + E E + E +
Sbjct: 711 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 770
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
+ AA+S + K T + +N + S K + G K A + +
Sbjct: 771 SEEAAASPAQVKTSVKKTQAKANPAAARAP---SAKGTISAPG----KVVTAAAQAKQRS 823
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAA-- 243
+ A A S +A A +A G E +G +E+ +E A
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 244 VAPEKPPA-SDETKAAEEPSKVEEKKAE------EAGASAAACEAPSAAGPGAPPEQEAA 296
+A KP + + +AA P+K +K + G SAA +A G+ E+ +
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDSGSSSEESDS 941
Query: 297 PAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
E PAA ++ P P SP P A A+
Sbjct: 942 DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
Score = 57.0 bits (136), Expect = 2e-08
Identities = 77/323 (23%), Positives = 120/323 (37%), Gaps = 35/323 (10%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78
PG+ + KA QE+ S AA S A+ + + A+ PAAA +
Sbjct: 744 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN---PAAARAP 800
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGE------AAEPGSPTAAEGEAASAASS 132
+A + + G+ AAA SP + + P A P S + A+AA +
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 860
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
+ P+ + G S+E ++ K SG K ++ A E+P +G
Sbjct: 861 QTGPEEDSG-----SSEEESDSEEEAETLAQVKPSG---KTHQIRAALAPAKESP-RKGA 911
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPAS 252
G +AA+AG + ++ E + GE AA Q KP V P + PA
Sbjct: 912 APTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAG 970
Query: 253 D-----ETKAAEEPSKVEEKKAEEAGASAAACE--------APSAAGPGAPPEQEAAPAE 299
+ +AA P K +A E+ A +++ E A PG P
Sbjct: 971 PAATPAQAQAASTPRKA---RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 1027
Query: 300 EPAAAAASSACAAPSQEAQPECS 322
P A +S A S + S
Sbjct: 1028 HPRIAPKASMAGASSSKESSRIS 1050
Score = 55.8 bits (133), Expect = 5e-08
Identities = 82/328 (25%), Positives = 127/328 (38%), Gaps = 25/328 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
+K A K E +E E + S +A VK + A S + G+ P
Sbjct: 260 AKRAKKPEEESESSEEGS--ESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
A P AG+ AS + A K E + ++ E +S E+E PA + +
Sbjct: 318 AP----PGKAGA-VASQTKAGKPEEDSESSSEE-SSDSEEETPAAKALLQAKASGKTSQV 371
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
A++A + SP+ GA P+P +T K + K+ S + + +E EA
Sbjct: 372 GAASAPAKESPR--KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-----EAP 424
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVA 245
A A GK A+A A E S + AAP A + G A Q K +E + +
Sbjct: 425 AQAKPSGKAPQVRAASAPAKE----SPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRS 477
Query: 246 PEKPPASD-ETKAAEEPSKVEE-KKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAA 303
+ SD E AA ++V+ K+ + ++ P G G P + PA A
Sbjct: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 304 AAA-SSACAAPSQEAQPECSPEAPPAEA 330
+ S+E+ E P A A
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVA 565
Score = 50.8 bits (120), Expect = 2e-06
Identities = 68/307 (22%), Positives = 121/307 (39%), Gaps = 36/307 (11%)
Query: 40 KVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG 99
K DA+ A ++ + + + S+ ++EE A A + A+P A A +
Sbjct: 64 KAEEDAALQAKKTRVSDPISTSESS---EEEEEAEAETAKATPRLASTNSSVLGA--DLP 118
Query: 100 ASPVEKEAPAEGEAAEPGS--PTAAEGEAASAASSTSSPK--AEDGATPSPSNETPKKKK 155
+S EK +A + G+ P A G+ + S SP+ AE A + +ET ++
Sbjct: 119 SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG- 177
Query: 156 KRFSFKKSFKLSGFSFKKNKKEAGEG-GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQ 214
S G + K AG+ +E ++ + + G + A+ A+S
Sbjct: 178 -------SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
Query: 215 AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEK------- 267
+P +AA G G + K A +E++++EE S+ EE+
Sbjct: 231 KESPARKAAPAP-GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS 289
Query: 268 --KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEA 325
KA E A AP+ PG PA + A A+ ++ +PE E+
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGK--------GATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 326 PPAEAAE 332
E+++
Sbjct: 342 SSEESSD 348
Score = 49.7 bits (117), Expect = 4e-06
Identities = 69/299 (23%), Positives = 107/299 (35%), Gaps = 38/299 (12%)
Query: 13 EAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSA---PAAD 68
E AAE + VA S S +G G N AS A + + + + +A P
Sbjct: 1185 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1244
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA------------AEP 116
+E +G SP K E A+ P+ P + + +P
Sbjct: 1245 QEAKPQQAAGMLSPKTGGK-EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1303
Query: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKK----KKKRFSFKKSFKLSGFSFK 172
A+ +A+ T + E + E+ +K +K++ S + + S K
Sbjct: 1304 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1363
Query: 173 KNKKEAGEGGEAEAPA--------AEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAA 224
K K AGEGGEA + +D+A+G + S P EE
Sbjct: 1364 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1423
Query: 225 GEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPS 283
G GGD K ++ EK + K E+ +EKK + AS E+PS
Sbjct: 1424 GMGTVEGGDQSNPKSKK-----EKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPS 1473
Score = 42.4 bits (98), Expect = 6e-04
Identities = 62/294 (21%), Positives = 103/294 (35%), Gaps = 18/294 (6%)
Query: 25 ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSA 84
A+SP + Q G K+ P E+Q AP + + ++ S + S
Sbjct: 1109 ATSPQSTSVQAKGTNKLRKPKLP---------EVQQATKAPESSDDSEDSSDSSSGSEED 1159
Query: 85 AEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATP 144
E G A +A G +P E E AAE ++E + + + S S G TP
Sbjct: 1160 GE-GPQGAKSAHTLGPTPSRTETLVEETAAE-----SSEDDVVAPSQSLLSGYMTPGLTP 1213
Query: 145 SPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAA 204
+ S + K S S L+ K+EA A + + G EAA G
Sbjct: 1214 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK 1273
Query: 205 AEAGAASGEQAAAPGEEAAAGEEGAAGGDP---QEAKPQEAAVAPEKPPASDETKAAEEP 261
+ A + G P EA+ Q + V E K +
Sbjct: 1274 SRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT 1333
Query: 262 SKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQ 315
+K +K E+ + + P+A P + +++ E A+ + + S+
Sbjct: 1334 TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSK 1387
Score = 33.1 bits (74), Expect = 0.35
Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 24/161 (14%)
Query: 29 SKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKG 88
S G E+ K++GD PAA +K+ K++ A G AS S +
Sbjct: 1337 SSRKGWESRKRKLSGD-QPAARTPRSKK------------KKKLGAGEGGEASVSPEKTS 1383
Query: 89 EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT-----------AAEGEAASAASSTSSPK 137
+ A AS KE +G G+ EG S S K
Sbjct: 1384 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKK 1443
Query: 138 AEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEA 178
D + KKK K+ S K S S KK KK A
Sbjct: 1444 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1484
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 70.9 bits (172), Expect = 2e-12
Identities = 90/320 (28%), Positives = 127/320 (39%), Gaps = 32/320 (10%)
Query: 15 AAERPG--EAAVASSPSKANGQENGHVKVNGDAS--PAA--AESGAKEELQANGSAPAAD 68
AA +PG A A S S+ + V G S PA A S + +E A +APA
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
Query: 69 KE-EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAA 127
K + G A P A +P + S E+EAPA + S + AA
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
Query: 128 SAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
SA + + K GATP+P P K S K+ K S ++ E E E P
Sbjct: 304 SAPAKGTPGK---GATPAP----PGKAGAVASQTKAGKPEEDS--ESSSEESSDSEEETP 354
Query: 188 AAEG-------GKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
AA+ GK G A+A A E S + AAP A G+ G A Q K +
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAP---APPGKTGPAVAKAQAGKRE 407
Query: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 300
E + + + S+E A+ +K K + ASA A E+P APP + A +
Sbjct: 408 EDSQSSSEESDSEEEAPAQ--AKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQ 465
Query: 301 PAAAAASSACAAPSQEAQPE 320
+ S+E+ +
Sbjct: 466 VQVGKQEEDSRSSSEESDSD 485
Score = 61.2 bits (147), Expect = 1e-09
Identities = 76/338 (22%), Positives = 116/338 (34%), Gaps = 29/338 (8%)
Query: 15 AAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAES--GAKEELQANGSAPAADKEEP 72
A+E+ + AS+P+K + G A A+++ G EE + S ++D EE
Sbjct: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
Query: 73 AAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG---EAASA 129
A A+ K AA+ A SP + APA P A G E + +
Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412
Query: 130 ASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKK-------EAGEGG 182
+S S + E A PS + P+ + K+S + K + G+
Sbjct: 413 SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472
Query: 183 EAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEA 242
E ++E + AA AA+ P G G G K
Sbjct: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK---- 528
Query: 243 AVAPEKPPAS------DETKAAEEPSKVEEKKAEEAGASAAA------CEAPSAAGPGAP 290
V P P A D ++EE S + + A A A +A + P
Sbjct: 529 -VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG 587
Query: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
P Q+A P A + S+E+ E PA
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/306 (24%), Positives = 117/306 (38%), Gaps = 49/306 (16%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEE-PAAAGSGA 79
+A SSP+K Q+ G V V A S + EE S+ +AD EE PAA +
Sbjct: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE-----SSDSADSEEAPAAMTAAQ 631
Query: 80 ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAE 139
A P A P+ A P + A + A T A +A +A S S A
Sbjct: 632 AKP---------ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
Query: 140 DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGG 199
G T P+ ++ + +E+ E A G+ ++ G
Sbjct: 683 AGGTQRPAEDS----------------------SSSEESDSEEEKTGLAVTVGQAKSVG- 719
Query: 200 AAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259
+ AAS + G+ A G G + K ++ + SD +AA
Sbjct: 720 ---KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 260 EPSKVEEK-KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQ 318
P++V+ K +A A+ AA APSA G + P + AAA + +PS+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAP-------GKVVTAAAQAKQRSPSKVKP 829
Query: 319 PECSPE 324
P +P+
Sbjct: 830 PVRNPQ 835
Score = 59.7 bits (143), Expect = 4e-09
Identities = 71/340 (20%), Positives = 127/340 (37%), Gaps = 27/340 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAK----EELQAN 61
S K +A E+ G+ S P A G+ ++ ++G + +AE A E +
Sbjct: 119 SSMKEKAKAETEKAGKTG-NSMPHPATGKTVANL-LSGKSPRKSAEPSANTTLVSETEEE 176
Query: 62 GSAPA-ADKEEPAAAGSGAASPSAAE----------KGEPAAAAAPEAGASPVEKEAPAE 110
GS PA +P +G A S+ + +G+P+ A +S KE+PA
Sbjct: 177 GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 111 GEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
A PG G+ + P A+ P +E+ ++ + S + +
Sbjct: 237 KAAPAPGKV----GDVTPQVKGGALPPAKRAKKPEEESESSEEGSE------SEEEAPAG 286
Query: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAA 230
+ K + + + A +A G A +AGA + + A EE + +
Sbjct: 287 TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
Query: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAP 290
+E +A + + + + AA P+K +K A + A G
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406
Query: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330
E + +EE + + A A PS +A + AP E+
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Score = 59.3 bits (142), Expect = 5e-09
Identities = 73/336 (21%), Positives = 121/336 (36%), Gaps = 20/336 (5%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
S A + P +A A+SP+ ++ G + + S ++ ES ++EE G A
Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE--KTGLAV 710
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
+ + G + S KG AP + E E + E +
Sbjct: 711 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 770
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
+ AA+S + K T + +N + S K + G K A + +
Sbjct: 771 SEEAAASPAQVKTSVKKTQAKANPAAARAP---SAKGTISAPG----KVVTAAAQAKQRS 823
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAA-- 243
+ A A S +A A +A G E +G +E+ +E A
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 244 VAPEKPPA-SDETKAAEEPSKVEEKKAE------EAGASAAACEAPSAAGPGAPPEQEAA 296
+A KP + + +AA P+K +K + G SAA +A G+ E+ +
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDSGSSSEESDS 941
Query: 297 PAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
E PAA ++ P P SP P A A+
Sbjct: 942 DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
Score = 57.0 bits (136), Expect = 2e-08
Identities = 77/323 (23%), Positives = 120/323 (37%), Gaps = 35/323 (10%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78
PG+ + KA QE+ S AA S A+ + + A+ PAAA +
Sbjct: 744 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN---PAAARAP 800
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGE------AAEPGSPTAAEGEAASAASS 132
+A + + G+ AAA SP + + P A P S + A+AA +
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 860
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
+ P+ + G S+E ++ K SG K ++ A E+P +G
Sbjct: 861 QTGPEEDSG-----SSEEESDSEEEAETLAQVKPSG---KTHQIRAALAPAKESP-RKGA 911
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPAS 252
G +AA+AG + ++ E + GE AA Q KP V P + PA
Sbjct: 912 APTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAG 970
Query: 253 D-----ETKAAEEPSKVEEKKAEEAGASAAACE--------APSAAGPGAPPEQEAAPAE 299
+ +AA P K +A E+ A +++ E A PG P
Sbjct: 971 PAATPAQAQAASTPRKA---RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 1027
Query: 300 EPAAAAASSACAAPSQEAQPECS 322
P A +S A S + S
Sbjct: 1028 HPRIAPKASMAGASSSKESSRIS 1050
Score = 55.8 bits (133), Expect = 5e-08
Identities = 82/328 (25%), Positives = 127/328 (38%), Gaps = 25/328 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
+K A K E +E E + S +A VK + A S + G+ P
Sbjct: 260 AKRAKKPEEESESSEEGS--ESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
A P AG+ AS + A K E + ++ E +S E+E PA + +
Sbjct: 318 AP----PGKAGA-VASQTKAGKPEEDSESSSEE-SSDSEEETPAAKALLQAKASGKTSQV 371
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
A++A + SP+ GA P+P +T K + K+ S + + +E EA
Sbjct: 372 GAASAPAKESPR--KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-----EAP 424
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVA 245
A A GK A+A A E S + AAP A + G A Q K +E + +
Sbjct: 425 AQAKPSGKAPQVRAASAPAKE----SPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRS 477
Query: 246 PEKPPASD-ETKAAEEPSKVEE-KKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAA 303
+ SD E AA ++V+ K+ + ++ P G G P + PA A
Sbjct: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 304 AAA-SSACAAPSQEAQPECSPEAPPAEA 330
+ S+E+ E P A A
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVA 565
Score = 50.8 bits (120), Expect = 2e-06
Identities = 68/307 (22%), Positives = 121/307 (39%), Gaps = 36/307 (11%)
Query: 40 KVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG 99
K DA+ A ++ + + + S+ ++EE A A + A+P A A +
Sbjct: 64 KAEEDAALQAKKTRVSDPISTSESS---EEEEEAEAETAKATPRLASTNSSVLGA--DLP 118
Query: 100 ASPVEKEAPAEGEAAEPGS--PTAAEGEAASAASSTSSPK--AEDGATPSPSNETPKKKK 155
+S EK +A + G+ P A G+ + S SP+ AE A + +ET ++
Sbjct: 119 SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG- 177
Query: 156 KRFSFKKSFKLSGFSFKKNKKEAGEG-GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQ 214
S G + K AG+ +E ++ + + G + A+ A+S
Sbjct: 178 -------SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
Query: 215 AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEK------- 267
+P +AA G G + K A +E++++EE S+ EE+
Sbjct: 231 KESPARKAAPAP-GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS 289
Query: 268 --KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEA 325
KA E A AP+ PG PA + A A+ ++ +PE E+
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGK--------GATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 326 PPAEAAE 332
E+++
Sbjct: 342 SSEESSD 348
Score = 49.7 bits (117), Expect = 4e-06
Identities = 69/299 (23%), Positives = 107/299 (35%), Gaps = 38/299 (12%)
Query: 13 EAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSA---PAAD 68
E AAE + VA S S +G G N AS A + + + + +A P
Sbjct: 1147 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1206
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA------------AEP 116
+E +G SP K E A+ P+ P + + +P
Sbjct: 1207 QEAKPQQAAGMLSPKTGGK-EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1265
Query: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKK----KKKRFSFKKSFKLSGFSFK 172
A+ +A+ T + E + E+ +K +K++ S + + S K
Sbjct: 1266 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1325
Query: 173 KNKKEAGEGGEAEAPA--------AEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAA 224
K K AGEGGEA + +D+A+G + S P EE
Sbjct: 1326 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1385
Query: 225 GEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPS 283
G GGD K ++ EK + K E+ +EKK + AS E+PS
Sbjct: 1386 GMGTVEGGDQSNPKSKK-----EKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPS 1435
Score = 37.4 bits (85), Expect = 0.019
Identities = 50/226 (22%), Positives = 87/226 (38%), Gaps = 20/226 (8%)
Query: 46 SPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEK 105
+P A+ +GA +++ + +E PA A A P + + G + + K
Sbjct: 1032 APKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPAT--SPQSTSVQAKGTNKLRK 1089
Query: 106 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFK 165
E + A ++ + E +S +SS S EDG E P+ K + +
Sbjct: 1090 PKLPEVQQATKAPESSDDSEDSSDSSSGSE---EDG-------EGPQGAKSAHTLGPTPS 1139
Query: 166 LSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAG 225
+ ++ E+ E + AP+ G A ++A A+ + ++P +
Sbjct: 1140 RTETLVEETAAESSE-DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL- 1197
Query: 226 EEGAAGGDP---QEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKK 268
AA DP QEAKPQ+AA E + P K + K
Sbjct: 1198 ---AAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1240
Score = 33.1 bits (74), Expect = 0.35
Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 24/161 (14%)
Query: 29 SKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKG 88
S G E+ K++GD PAA +K+ K++ A G AS S +
Sbjct: 1299 SSRKGWESRKRKLSGD-QPAARTPRSKK------------KKKLGAGEGGEASVSPEKTS 1345
Query: 89 EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT-----------AAEGEAASAASSTSSPK 137
+ A AS KE +G G+ EG S S K
Sbjct: 1346 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKK 1405
Query: 138 AEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEA 178
D + KKK K+ S K S S KK KK A
Sbjct: 1406 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1446
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 70.9 bits (172), Expect = 2e-12
Identities = 90/320 (28%), Positives = 127/320 (39%), Gaps = 32/320 (10%)
Query: 15 AAERPG--EAAVASSPSKANGQENGHVKVNGDAS--PAA--AESGAKEELQANGSAPAAD 68
AA +PG A A S S+ + V G S PA A S + +E A +APA
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
Query: 69 KE-EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAA 127
K + G A P A +P + S E+EAPA + S + AA
Sbjct: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
Query: 128 SAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
SA + + K GATP+P P K S K+ K S ++ E E E P
Sbjct: 304 SAPAKGTPGK---GATPAP----PGKAGAVASQTKAGKPEEDS--ESSSEESSDSEEETP 354
Query: 188 AAEG-------GKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
AA+ GK G A+A A E S + AAP A G+ G A Q K +
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAP---APPGKTGPAVAKAQAGKRE 407
Query: 241 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 300
E + + + S+E A+ +K K + ASA A E+P APP + A +
Sbjct: 408 EDSQSSSEESDSEEEAPAQ--AKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQ 465
Query: 301 PAAAAASSACAAPSQEAQPE 320
+ S+E+ +
Sbjct: 466 VQVGKQEEDSRSSSEESDSD 485
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/306 (24%), Positives = 117/306 (38%), Gaps = 49/306 (16%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEE-PAAAGSGA 79
+A SSP+K Q+ G V V A S + EE S+ +AD EE PAA +
Sbjct: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE-----SSDSADSEEAPAAMTAAQ 631
Query: 80 ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAE 139
A P A P+ A P + A + A T A +A +A S S A
Sbjct: 632 AKP---------ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
Query: 140 DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGG 199
G T P+ ++ + +E+ E A G+ ++ G
Sbjct: 683 AGGTQRPAEDS----------------------SSSEESDSEEEKTGLAVTVGQAKSVG- 719
Query: 200 AAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259
+ AAS + G+ A G G + K ++ + SD +AA
Sbjct: 720 ---KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 260 EPSKVEEK-KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQ 318
P++V+ K +A A+ AA APSA G + P + AAA + +PS+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAP-------GKVVTAAAQAKQRSPSKVKP 829
Query: 319 PECSPE 324
P +P+
Sbjct: 830 PVRNPQ 835
Score = 59.7 bits (143), Expect = 4e-09
Identities = 71/340 (20%), Positives = 127/340 (37%), Gaps = 27/340 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAK----EELQAN 61
S K +A E+ G+ S P A G+ ++ ++G + +AE A E +
Sbjct: 119 SSMKEKAKAETEKAGKTG-NSMPHPATGKTVANL-LSGKSPRKSAEPSANTTLVSETEEE 176
Query: 62 GSAPA-ADKEEPAAAGSGAASPSAAE----------KGEPAAAAAPEAGASPVEKEAPAE 110
GS PA +P +G A S+ + +G+P+ A +S KE+PA
Sbjct: 177 GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 111 GEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
A PG G+ + P A+ P +E+ ++ + S + +
Sbjct: 237 KAAPAPGKV----GDVTPQVKGGALPPAKRAKKPEEESESSEEGSE------SEEEAPAG 286
Query: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAA 230
+ K + + + A +A G A +AGA + + A EE + +
Sbjct: 287 TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
Query: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAP 290
+E +A + + + + AA P+K +K A + A G
Sbjct: 347 SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406
Query: 291 PEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330
E + +EE + + A A PS +A + AP E+
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
Score = 55.8 bits (133), Expect = 5e-08
Identities = 82/328 (25%), Positives = 127/328 (38%), Gaps = 25/328 (7%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
+K A K E +E E + S +A VK + A S + G+ P
Sbjct: 260 AKRAKKPEEESESSEEGS--ESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
A P AG+ AS + A K E + ++ E +S E+E PA + +
Sbjct: 318 AP----PGKAGA-VASQTKAGKPEEDSESSSEE-SSDSEEETPAAKALLQAKASGKTSQV 371
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
A++A + SP+ GA P+P +T K + K+ S + + +E EA
Sbjct: 372 GAASAPAKESPR--KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-----EAP 424
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVA 245
A A GK A+A A E S + AAP A + G A Q K +E + +
Sbjct: 425 AQAKPSGKAPQVRAASAPAKE----SPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRS 477
Query: 246 PEKPPASD-ETKAAEEPSKVEE-KKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAA 303
+ SD E AA ++V+ K+ + ++ P G G P + PA A
Sbjct: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
Query: 304 AAA-SSACAAPSQEAQPECSPEAPPAEA 330
+ S+E+ E P A A
Sbjct: 538 VGKWEEDSESSSEESSDSSDGEVPTAVA 565
Score = 50.8 bits (120), Expect = 2e-06
Identities = 68/307 (22%), Positives = 121/307 (39%), Gaps = 36/307 (11%)
Query: 40 KVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG 99
K DA+ A ++ + + + S+ ++EE A A + A+P A A +
Sbjct: 64 KAEEDAALQAKKTRVSDPISTSESS---EEEEEAEAETAKATPRLASTNSSVLGA--DLP 118
Query: 100 ASPVEKEAPAEGEAAEPGS--PTAAEGEAASAASSTSSPK--AEDGATPSPSNETPKKKK 155
+S EK +A + G+ P A G+ + S SP+ AE A + +ET ++
Sbjct: 119 SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG- 177
Query: 156 KRFSFKKSFKLSGFSFKKNKKEAGEG-GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQ 214
S G + K AG+ +E ++ + + G + A+ A+S
Sbjct: 178 -------SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
Query: 215 AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEK------- 267
+P +AA G G + K A +E++++EE S+ EE+
Sbjct: 231 KESPARKAAPAP-GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS 289
Query: 268 --KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEA 325
KA E A AP+ PG PA + A A+ ++ +PE E+
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGK--------GATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 326 PPAEAAE 332
E+++
Sbjct: 342 SSEESSD 348
Score = 50.1 bits (118), Expect = 3e-06
Identities = 66/311 (21%), Positives = 113/311 (36%), Gaps = 20/311 (6%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
S A + P +A A+SP+ ++ G + + S ++ ES ++EE G A
Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE--KTGLAV 710
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
+ + G + S KG AP + E E + E +
Sbjct: 711 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 770
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
+ AA+S + K T + +N + S K + G K A + +
Sbjct: 771 SEEAAASPAQVKTSVKKTQAKANPAAARAP---SAKGTISAPG----KVVTAAAQAKQRS 823
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAA-- 243
+ A A S +A A +A G E +G +E+ +E A
Sbjct: 824 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 244 VAPEKPPA-SDETKAAEEPSKVEEKKAE------EAGASAAACEAPSAAGPGAPPEQEAA 296
+A KP + + +AA P+K +K + G SAA +A G+ E+ +
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDSGSSSEESDS 941
Query: 297 PAEEPAAAAAS 307
E PAA ++
Sbjct: 942 DGEAPAAVTSA 952
Score = 43.9 bits (102), Expect = 2e-04
Identities = 50/219 (22%), Positives = 88/219 (40%), Gaps = 18/219 (8%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78
PG+ + KA QE+ S AA S A+ + + A+ PAAA +
Sbjct: 744 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN---PAAARAP 800
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGE------AAEPGSPTAAEGEAASAASS 132
+A + + G+ AAA SP + + P A P S + A+AA +
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 860
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGF-SFKKNKKEAGEGGEAEAP---- 187
+ P+ ED + +++ ++ + K S K + KE+ G A P
Sbjct: 861 QTGPE-EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT 919
Query: 188 ---AAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAA 223
AA+ GK + +G ++ + G A +A +E++
Sbjct: 920 GPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQDQESS 958
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 70.5 bits (171), Expect = 2e-12
Identities = 80/290 (27%), Positives = 107/290 (36%), Gaps = 38/290 (13%)
Query: 55 KEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAA 114
K +++ +A K+ PAAA AA P E E A+ G S E+E E EA
Sbjct: 670 KLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEAS-----GVSGNEEEMVEEAEAL 724
Query: 115 EPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKN 174
GE + A+ +S E + PSP E K +G + K
Sbjct: 725 HASGNEVPRGECSGPATVNNSSDTE--SIPSPHTEAAKD-------------TGQNGPKP 769
Query: 175 KKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDP 234
G G P +D A A+EA A A P A P
Sbjct: 770 PATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVV------P 823
Query: 235 QEAKPQEAAVAP-------EKPPASDE----TKAAEEPSKVE-EKKAEEAGASAAACEAP 282
+E K +E A AP +KPPA++E T AEEP K E ++AEE A EA
Sbjct: 824 KEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAA 883
Query: 283 SAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
A GA ++ A A SS S + + E AE +
Sbjct: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGD 933
Score = 56.2 bits (134), Expect = 4e-08
Identities = 82/351 (23%), Positives = 123/351 (35%), Gaps = 53/351 (15%)
Query: 2 GAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGH------VKVNGDASPAAAESGAK 55
G + + G A + SP ++ G + D P +
Sbjct: 728 GNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPP 787
Query: 56 EELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAE 115
E++ PA + PA+ +GA +P P A +P A V KE E AA
Sbjct: 788 EDI------PAPTEPTPASEATGAPTP-------PPAPPSPSAPPPVVPKEEKEEETAAA 834
Query: 116 PGSPTAAEGEAASAAS-STSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKN 174
P E + +A + + KAE+ + E + K + + + + K
Sbjct: 835 PPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAE 894
Query: 175 KKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASG---EQAAAPGEEAAAGEEGAAG 231
KKE G G A + G ++ A +A E A G + +P
Sbjct: 895 KKEGG-SGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLL-----TPT 948
Query: 232 GDPQEAKPQEAAVAPEKPPASDETK--AAEEP---SKVEEKKAEEAGASAAACEAPSAAG 286
GDP+ A +P+KP + K AA P +KV E E+A AP+
Sbjct: 949 GDPR------ANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDA--------APTKPA 994
Query: 287 PGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAP-----PAEAAE 332
P APP + E A S+ S+ P EA PA AAE
Sbjct: 995 PPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAE 1045
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 69.3 bits (168), Expect = 4e-12
Identities = 95/362 (26%), Positives = 135/362 (37%), Gaps = 50/362 (13%)
Query: 2 GAQFSKTAAKGEAAAERPGEAAVASSP-SKANGQENGHVKVNGDASPAAAESGAKEELQA 60
G++ ++ A +G AA + G P ++A G H + AE GA E
Sbjct: 43 GSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETE-------AEEGAPE---- 91
Query: 61 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 120
P +E A ASP +GEP EA P + AP E AE P
Sbjct: 92 GAEVPQGGEETSGAQQVEGASPGRGAQGEPRG----EAQREPEDSAAPERQEEAEQ-RPE 146
Query: 121 AAEGEAASAASST---SSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKE 177
EG A+ A + P ++ P+ ++ + + + + +G S +
Sbjct: 147 VPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDA-EGP 205
Query: 178 AGEGGEAEAPA-----AEG--GKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAG-EEGA 229
G+ +AE PA AEG G A G A + +A G+ A G+ A G E G
Sbjct: 206 LGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEA-GDPAGDGVEAGV 264
Query: 230 AGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSK------------VEEKKAEEAGAS-- 275
GD EA+ + PA + + EP + +E E AG S
Sbjct: 265 PAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPG 324
Query: 276 -AAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQ-----EAQPECSPEAPPAE 329
A A A PG +EAAP + A A P Q E + E SPE P E
Sbjct: 325 ELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREE 384
Query: 330 AA 331
A
Sbjct: 385 EA 386
Score = 55.5 bits (132), Expect = 7e-08
Identities = 60/229 (26%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 15 AAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE--EP 72
A R G++ A P+ +G E G GD+ AE A + + A G A A + EP
Sbjct: 242 AEGRVGDSVEAGDPA-GDGVEAGVPA--GDS--VEAEGPAGDSMDAEGPAGRARRVSGEP 296
Query: 73 AAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASS 132
+G G+ SP A AA AG SP E A EA PG + E A +
Sbjct: 297 QQSGDGSLSPQAEAI---EVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARAD 353
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
+ DG P + ++++ S + ++E GGE E+P
Sbjct: 354 AGEDRVGDGPQQEPGEDEERRER--------------SPEGPREEEAAGGEEESP----- 394
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQE 241
G A+ AAE A A G +GE G ++ + E
Sbjct: 395 DSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASE 443
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/153 (27%), Positives = 57/153 (37%), Gaps = 12/153 (7%)
Query: 179 GEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAK 238
G G E PA E G AA EA G + A AA + A GG P
Sbjct: 13 GPQGPPEVPAPLA---ERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
Query: 239 PQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPA 298
EA ++ + A E ++V + E +GA +P G GA E
Sbjct: 70 EAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASP---GRGAQGEPRGEAQ 126
Query: 299 EEPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331
EP + AAP ++ + E PE P A+
Sbjct: 127 REPEDS------AAPERQEEAEQRPEVPEGSAS 153
Score = 47.8 bits (112), Expect = 1e-05
Identities = 57/244 (23%), Positives = 80/244 (32%), Gaps = 49/244 (20%)
Query: 67 ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEA 126
A+ EP G P E P A E GA+ E E P E AE AA +
Sbjct: 2 AEAAEPEGVAPGPQGPP--EVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKE 59
Query: 127 ASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEA 186
A P+AE T ET EA EG A
Sbjct: 60 AGGGGPDRGPEAEARGTRGAHGET--------------------------EAEEGAPEGA 93
Query: 187 PAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQE-AKPQEAAVA 245
+GG+ E A + A+PG A G A +P++ A P+ A
Sbjct: 94 EVPQGGE------------ETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEA 141
Query: 246 PEKPPASDETKAAEEPSKVEEK-----KAEEAGASAAACEAPSAAGPGAP---PEQEAAP 297
++P + + + E V+ + E G + + EA G P ++
Sbjct: 142 EQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVD 201
Query: 298 AEEP 301
AE P
Sbjct: 202 AEGP 205
Score = 38.5 bits (88), Expect = 0.008
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 9/129 (6%)
Query: 201 AAAAAEAGAASGEQAA----APGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETK 256
A AA G A G Q AP E GE GAAGG+ + P+ + A E P + K
Sbjct: 2 AEAAEPEGVAPGPQGPPEVPAPLAERP-GEPGAAGGEAE--GPEGSEGAEEAPRGAAAVK 58
Query: 257 AAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQE 316
A +AE G A E + A GAP E E + A A+P +
Sbjct: 59 EAGGGGPDRGPEAEARGTRGAHGE--TEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRG 116
Query: 317 AQPECSPEA 325
AQ E EA
Sbjct: 117 AQGEPRGEA 125
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 65.5 bits (158), Expect = 6e-11
Identities = 97/358 (27%), Positives = 131/358 (36%), Gaps = 56/358 (15%)
Query: 8 TAAKGEAAAERPGE-AAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPA 66
TAA + E P AA +P + SPAAA +E + P
Sbjct: 989 TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPT 1048
Query: 67 ADKE-EPAAA--------GSGAASPSAAEKGEPAAAA-APEAGASPVEK----EAPAEGE 112
++ PAAA AA P+ E PAAA PE SP E P
Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
Query: 113 AA-----EPGSPTAAEGEAASAASSTSS-PKAEDGATPSPSNETPKKKKKRFSFKKSFKL 166
AA EP SP AA AS ++ P E+ A P+P+ TP++
Sbjct: 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS---------- 1158
Query: 167 SGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGE 226
+ + ++ A PA + A+ A A E + P A E
Sbjct: 1159 AAVAVPTPEESASPAAAVPTPA-----ESASFAAVVATLEEPTSPAASVPTPAAMVATLE 1213
Query: 227 E--GAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSA 284
E A P +P A A P + AA P+ E + A + +P+A
Sbjct: 1214 EFTSPAASVPTSEEPASLAAAVSNPE-EPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAA 1272
Query: 285 AGPGAPPEQEAAPA------EEPAAAAASSACAAPSQE--AQPECS---PEAPPAEAA 331
+ P PE+ A+PA EEPA+ AA A P+ E A P S PE P AA
Sbjct: 1273 SVP--TPEEPASPAAAVSNLEEPASPAA----AVPTPEVAAIPAASVPTPEVPAIPAA 1324
Score = 59.7 bits (143), Expect = 4e-09
Identities = 72/318 (22%), Positives = 106/318 (33%), Gaps = 36/318 (11%)
Query: 9 AAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAAD 68
AA E AA +P + SPAAA +E A+ +A
Sbjct: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP--ASPAAAVPT 1126
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAAS 128
EEPA+ + +P PA E+ ++ V P E + PT AE + +
Sbjct: 1127 PEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
Query: 129 AASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPA 188
A +T E+ +P+ S TP E +PA
Sbjct: 1187 AVVAT----LEEPTSPAASVPTPAAMVATLE-----------------------EFTSPA 1219
Query: 189 AEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEK 248
A E AAA + + AA P E A + + P + PE+
Sbjct: 1220 ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEE 1279
Query: 249 P--PASDETKAAEEPSKVEEKKAEEAGASAAAC----EAPSAAGPGAPPEQEAAPAEEPA 302
P PA+ + E S E A AA E P+ PP +E +P P
Sbjct: 1280 PASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPF 1339
Query: 303 AAAASSACAAP-SQEAQP 319
++ + P S+E P
Sbjct: 1340 LGVSAHTDSVPISEEGTP 1357
Score = 58.2 bits (139), Expect = 1e-08
Identities = 98/345 (28%), Positives = 128/345 (37%), Gaps = 56/345 (16%)
Query: 8 TAAKGEAAAERPGEAAV-ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPA 66
T A A E P AAV S+P + ASPAAA +E + P
Sbjct: 976 TPATTVHAPEEPDTAAVRVSTPEEP-------------ASPAAAVPTPEEPTSPAAAVPT 1022
Query: 67 ADKEEPAAAGSGAASPSAAEKGEPAAAA-APEAGASPVEKEAPAEGEAAEPGSPTAA--- 122
EEP + AA P E PAAA PE SP A A EP SP AA
Sbjct: 1023 P--EEPTSPA--AAVPPPEEPTSPAAAVPTPEEPTSP----AAAVPTPEEPTSPAAAVPT 1074
Query: 123 ---EGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAG 179
A+A + P + A P+P E P + + ++ A
Sbjct: 1075 PEEPTSPAAAVPTPEEPTSPAAAVPTP--EEPTSPAAAVPTPEEPASPAAAVPTPEEPAS 1132
Query: 180 EGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP 239
P +E A A A +AS A EE+A+ AA P E+
Sbjct: 1133 PAAAVPTP------EEPAFPAPAVPTPEESASAAVAVPTPEESAS--PAAAVPTPAESAS 1184
Query: 240 QEAAVA----PEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEA 295
A VA P P AS T AA + E+ A + + E S A + PE+
Sbjct: 1185 FAAVVATLEEPTSPAASVPTPAAMVATL--EEFTSPAASVPTSEEPASLAAAVSNPEEPT 1242
Query: 296 APA------EEPAAAAASSACAAPSQEAQPECS---PEAPPAEAA 331
+PA EEP ++AA A P + + P S PE P + AA
Sbjct: 1243 SPAAAVPTLEEPTSSAA--AVLTPEELSSPAASVPTPEEPASPAA 1285
Score = 55.5 bits (132), Expect = 7e-08
Identities = 88/336 (26%), Positives = 119/336 (35%), Gaps = 62/336 (18%)
Query: 7 KTAAKGEAAAERPGEAAVAS-SPSKAN-------GQENGHVKVNGDASPAAAESGAKEEL 58
+TA AA + G +AVA SP A +E+G + G +PA +E
Sbjct: 931 ETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPE--GPVTPATTVHAPEEPD 988
Query: 59 QANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAA-APEAGASPVEKEAPAEGEAAEPG 117
A + + EEPA+ AA P+ E PAAA PE SP P E EP
Sbjct: 989 TA--AVRVSTPEEPASPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE----EPT 1040
Query: 118 SPTAAEGEAASAASSTSS-PKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKK 176
SP AA S ++ P E+ +P+ + TP+
Sbjct: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE------------------------ 1076
Query: 177 EAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQE 236
E +PAA E AAA + AA P E A A +
Sbjct: 1077 ------EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP 1130
Query: 237 AKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAA 296
A P A PE+P A P+ E A A + +P+AA P
Sbjct: 1131 ASPAAAVPTPEEPAFP----APAVPTPEESASAAVAVPTPEESASPAAAVP--------T 1178
Query: 297 PAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
PAE + AA + P+ A +P A A E
Sbjct: 1179 PAESASFAAVVATLEEPTSPAASVPTPAAMVATLEE 1214
Score = 52.4 bits (124), Expect = 6e-07
Identities = 75/296 (25%), Positives = 105/296 (35%), Gaps = 47/296 (15%)
Query: 63 SAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPV-----------------EK 105
+ PA P + AA S E AAA + G S V E+
Sbjct: 908 TVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEE 967
Query: 106 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFK 165
+ EG P + A E +AA S+P E+ A+P+ + TP++ + + +
Sbjct: 968 DGTPEGPVT-PATTVHAPEEPDTAAVRVSTP--EEPASPAAAVPTPEEPTSPAAAVPTPE 1024
Query: 166 LSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAG 225
E +PAA E AAA + AA P E
Sbjct: 1025 -----------------EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
Query: 226 EEGAAGGDPQEAKPQEAAVAPEKP--PASDETKAAEEPSKVEEKKAEEAGASAAAC---- 279
A + P A PE+P PA+ E S E AS AA
Sbjct: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP 1127
Query: 280 EAPSAAGPGAP-PEQEA--APAEEPAAAAASSACAAPSQEAQPECSPEAP-PAEAA 331
E P++ P PE+ A APA +AS+A A P+ E + P PAE+A
Sbjct: 1128 EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
Score = 38.9 bits (89), Expect = 0.006
Identities = 53/216 (24%), Positives = 72/216 (33%), Gaps = 18/216 (8%)
Query: 130 ASSTSSPKAEDG----ATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
A + P E+G A P+P F + S S ++ A E
Sbjct: 846 ALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPE 905
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEG---AAGGDPQEAKPQ-- 240
G AA AA S + AP AA +EG AG P+ A
Sbjct: 906 RATVPAVTVSVPEGTAAVAA----VSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAIT 961
Query: 241 ----EAAVAPEKPPASDET-KAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEA 295
E PE P T A EEP + + ++ A P+ P +P
Sbjct: 962 VPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021
Query: 296 APAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331
P E + AAA P+ A +PE P + AA
Sbjct: 1022 TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA 1057
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 65.5 bits (158), Expect = 6e-11
Identities = 67/328 (20%), Positives = 128/328 (39%), Gaps = 28/328 (8%)
Query: 9 AAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAAD 68
A + + R E + A P + + VK++ + + AKE L A
Sbjct: 2432 ATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGG 2491
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEG----EAAEPGSPTAAEG 124
+EP + S + P AA EP A P+A + +E P G ++ P SP A+
Sbjct: 2492 WQEPKSLLSLGSYPPAAGSSEPKAPW-PKATDGDLAQE-PGPGLTFEDSGNPKSPDKAQA 2549
Query: 125 EAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEA 184
E A S SS + G++ S S+ + S S + ++E + G+
Sbjct: 2550 EQDGAEESESSSSSSSGSSSSSSSSS----------------SSGSETEGEEEGDKNGDG 2593
Query: 185 EAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAV 244
GG++ +A + AA+ + ++S +++ +++ ++ + ++
Sbjct: 2594 GC--GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651
Query: 245 APEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAA 304
+ +S + ++ S + + A AP+A GP A Q A P + A
Sbjct: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTA-GPSA---QAALPTKATKQA 2707
Query: 305 AASSACAAPSQEAQPECSPEAPPAEAAE 332
+ A + P P+APP + +
Sbjct: 2708 GKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735
Score = 55.8 bits (133), Expect = 5e-08
Identities = 53/241 (21%), Positives = 96/241 (39%), Gaps = 24/241 (9%)
Query: 16 AERPG------EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADK 69
A+ PG ++ SP KA +++G + +S ++ S + ++GS ++
Sbjct: 2526 AQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEE 2585
Query: 70 EEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASA 129
E G + G +AA ASP A+ S +++ ++S+
Sbjct: 2586 EGDKNGDGGCGT------GGRNCSAASSRAASP----------ASSSSSSSSSSSSSSSS 2629
Query: 130 ASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAA 189
+SS+SS + ++ S S+ + S S S S ++ + + APA
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP 2689
Query: 190 EGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDP-QEAKPQEAAVAPEK 248
G A A +AG A A +PG++ A + A P Q +P+ A A +
Sbjct: 2690 TAGPSAQAALPTKATKQAGKAR-PSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSR 2748
Query: 249 P 249
P
Sbjct: 2749 P 2749
Score = 52.0 bits (123), Expect = 7e-07
Identities = 58/281 (20%), Positives = 97/281 (34%), Gaps = 17/281 (6%)
Query: 6 SKTAAKGEAAAERPGEA---------AVASSPSKANGQENGHVKVNGDASPAAAESGAKE 56
SK A + E PG ++ S P A E A E G
Sbjct: 2474 SKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGL 2533
Query: 57 ELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEP 116
+ +G+ + DK + G+ S S++ +++++ + +S E E EG+
Sbjct: 2534 TFEDSGNPKSPDKAQAEQDGA-EESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGD 2592
Query: 117 G-------SPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGF 169
G + +AA AAS ASS+SS + ++ S S+ + S S S
Sbjct: 2593 GGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2652
Query: 170 SFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGA 229
S + + + + + + AA A S + A AG+
Sbjct: 2653 SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARP 2712
Query: 230 AGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAE 270
+ P + P AP P A+ +K KK E
Sbjct: 2713 SAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKRE 2753
Score = 49.3 bits (116), Expect = 5e-06
Identities = 64/308 (20%), Positives = 105/308 (34%), Gaps = 47/308 (15%)
Query: 67 ADKEEPAAAGSGAA-SPSAAEKGE--------------PAAAAAPEAGASPVEKEAP--- 108
A EEP A G PSA KG+ P+ A E ++P K++P
Sbjct: 2320 AGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEP 2379
Query: 109 ----AEGEAAEPGSPTAAEGEAASAASSTSSPKAE-----DGATPSPSNETPKKKKKRFS 159
A+ A P P + A + P AE P+P P + K
Sbjct: 2380 VDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPK--- 2436
Query: 160 FKKSFKLSGFSFKKNKKEAGEGGE---------AEAPAAEGGK-------DEAAGGAAAA 203
K + + S K + GE E +P ++ K D AGG
Sbjct: 2437 -PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEP 2495
Query: 204 AAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSK 263
+ S AA E A + G QE P P + D+ +A ++ ++
Sbjct: 2496 KSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAE 2555
Query: 264 VEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSP 323
E + + S+++ + S++G E+E + C+A S A S
Sbjct: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
Query: 324 EAPPAEAA 331
+ + ++
Sbjct: 2616 SSSSSSSS 2623
Score = 46.2 bits (108), Expect = 4e-05
Identities = 56/194 (28%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 142 ATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAA 201
A PSP+ P K++ +K K+ GEG +GG AG
Sbjct: 2289 AEPSPALLVPSAKRRS--------------RKTSKDTGEG-------KDGG---TAGSEE 2324
Query: 202 AAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEP 261
A G A A G+ AA EE G E A+ P P S ++ P
Sbjct: 2325 PGAKARGRGRKPSAKAKGDRAATLEE---GNPTDEVPSTPLALEPSSTPGSKKS-----P 2376
Query: 262 SKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAA---AAASSACAAPSQEAQ 318
+ +K+A+ + A AP P APP + PA EP A A A+S AP
Sbjct: 2377 PEPVDKRAK----APKARPAPPQPSP-APPAFTSCPAPEPFAELPAPATSLAPAP-LITM 2430
Query: 319 PECSPEAPPAEAAE 332
P P+ A AAE
Sbjct: 2431 PATRPKPKKARAAE 2444
Score = 43.9 bits (102), Expect = 2e-04
Identities = 61/260 (23%), Positives = 92/260 (35%), Gaps = 33/260 (12%)
Query: 1 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA 60
+G +F T ++ E + A + P K G+ S AA GA+
Sbjct: 1906 LGTEFEYTDSESEVKVRKRSPAGLLR-PKKGLGEPG--------PSLAAPTPGAR----- 1951
Query: 61 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 120
G P++ + A G + EP A PEA + +E S
Sbjct: 1952 -GPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDAS-- 2008
Query: 121 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE 180
AA S A +T + + G SP + + K ++ KK K KEAG
Sbjct: 2009 AAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKK----------KKGKEAGP 2058
Query: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 240
G P A EA A A+ AA +A A G+E G G +K
Sbjct: 2059 GAGLPPPRAPALPSEA---RAPHASSLTAAKRSKAKAKGKEVKKENRGKGGA---VSKLM 2112
Query: 241 EAAVAPEKPPASDETKAAEE 260
E+ A E + ++ +E+
Sbjct: 2113 ESMAAEEDFEPNQDSSFSED 2132
Score = 42.0 bits (97), Expect = 8e-04
Identities = 32/151 (21%), Positives = 62/151 (41%), Gaps = 6/151 (3%)
Query: 2 GAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQAN 61
G S +++ + A ++ +SS S ++ + + +S +++ S + ++
Sbjct: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Query: 62 GSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAA----EPG 117
S+ ++ ++ +S S+ ++ PA A P A A+ K G+A PG
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPG 2718
Query: 118 SPTAAEGEAASAASSTS--SPKAEDGATPSP 146
T A A T PKA+ GA P
Sbjct: 2719 KKTPAPQPQAPPPQPTQPLQPKAQAGAKSRP 2749
Score = 42.0 bits (97), Expect = 8e-04
Identities = 31/150 (20%), Positives = 62/150 (41%), Gaps = 2/150 (1%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
S +++ +++ ++ +SS S ++ + + +S +++ S + + S
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCS 2680
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
+ D+ PA +A + K A A + SP K+ PA A P PT
Sbjct: 2681 SDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSP-GKKTPAPQPQAPPPQPTQPLQP 2739
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKK 155
A A + S PK +G + E K+++
Sbjct: 2740 KAQAGAK-SRPKKREGVHLPTTKELAKRQR 2768
Score = 39.7 bits (91), Expect = 0.004
Identities = 63/280 (22%), Positives = 101/280 (36%), Gaps = 40/280 (14%)
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKA 138
A SP A+E + E ++ E PA+G ++ +P+ A + + PK
Sbjct: 1718 AHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKL 1777
Query: 139 EDGATPSPSNETPK---KKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAE----G 191
+P PK +K+ F + SF + +E+ + E+ E
Sbjct: 1778 TKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELE 1837
Query: 192 GKDEAAGGAAAAAAEAGAASGEQAAAPG-EEAAAG--EEGAAGGDPQ------------E 236
+DEA+GG A E+A +PG EE+ G AA P E
Sbjct: 1838 EEDEASGGGYRLGAR------ERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLE 1891
Query: 237 AKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAG-----------ASAAACEAPSAA 285
AK + + E + + S+V+ +K AG + A P A
Sbjct: 1892 AKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGAR 1951
Query: 286 GPG-APPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPE 324
GP + P++ E+ A P EA PE S +
Sbjct: 1952 GPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDD 1991
Score = 39.3 bits (90), Expect = 0.005
Identities = 76/337 (22%), Positives = 110/337 (32%), Gaps = 48/337 (14%)
Query: 13 EAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEP 72
EA ERPG +AS A +E E+G LQA +P P
Sbjct: 379 EAFDERPGPIQIASQARDARARER--------------EAGRPGVLQAPPGSP-----RP 419
Query: 73 AAAGSGAASPSAAEKG--EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAA 130
G ++ + P A AP A+ + A A E P A A
Sbjct: 420 LDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAP 479
Query: 131 SSTSSPKAEDGATP---SPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
+ P A+ A P P + ++ K F+L F+ + A + + A
Sbjct: 480 RGPAGPAAQQAAKLFGLEPGRPPPTGPEHKW---KPFELGNFAATQMAVLAAQHHHSRA- 535
Query: 188 AAEGGKDEAAGGAAAAAAEA----GAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ--- 240
++EAA AA+++ +A GA AA G A A G A
Sbjct: 536 -----EEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIK 590
Query: 241 ------EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQE 294
AVA ++ + E AGAS A P + GP A ++
Sbjct: 591 YSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQ 650
Query: 295 AAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331
+P ++ A AQ E PP A
Sbjct: 651 L--KRDPERPESAKAFGREGSGAQGEAEVRHPPVGIA 685
Score = 37.0 bits (84), Expect = 0.024
Identities = 68/285 (23%), Positives = 93/285 (32%), Gaps = 32/285 (11%)
Query: 49 AAESGAKEELQANGSAPAADKEE-----PAAAGSGAASPSAAEKGEPAAAAAPEAGASPV 103
A GAKE + + A + E P S P A KG PA AA AG V
Sbjct: 300 AGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTV 359
Query: 104 EKEAPAEGEAAEPGSPTAAEG--------EAASAASSTSSPKAEDG---------ATPSP 146
+E E P + E + AS A + + E G +P P
Sbjct: 360 FREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRP 419
Query: 147 SNETPKKKKKRFSFKKSFKLSGFSFKKNKK--EAGEGGEAEAPAAEGGKDEAAGGAAAAA 204
+ P+ +++ S +S K + + A A PA E K EA A
Sbjct: 420 LDR-PEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERA 478
Query: 205 AEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKV 264
A P + AA G G P P+ E + A
Sbjct: 479 PRG-------PAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHH 531
Query: 265 EEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSA 309
+ EEA AA+ + PGA + AA P A S+A
Sbjct: 532 HSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAA 576
Score = 36.6 bits (83), Expect = 0.032
Identities = 71/311 (22%), Positives = 105/311 (33%), Gaps = 68/311 (21%)
Query: 65 PAADKEEP------AAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEG------- 111
PA +++P A + S S+ E + ++ E +E+E A G
Sbjct: 1792 PATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGA 1851
Query: 112 --EAAEPGSPTAAEGEAAS-AASSTSSPKAEDGAT--PSPSNETPKKKKKRFSFK----- 161
A PG + G A AAS+ SP + + + +KK++R S
Sbjct: 1852 RERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFE 1911
Query: 162 --------KSFKLSGFSFKKNKKEAGEGGEAEAPAAEG--GKDEAAGGAAAAAAEAGAAS 211
K K S + KK GE G + A G G D ++ A A E G +
Sbjct: 1912 YTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKA 1971
Query: 212 GEQAAAPGEEAAAGEEGAAGG-------------DPQEAKPQEAAVAPEKP--------- 249
+ AG E + D A P + AP
Sbjct: 1972 RKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGP 2031
Query: 250 --PASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAAS 307
P D +A + ++KK +EAG G G PP + A E A AS
Sbjct: 2032 LSPRKDAGRAKDRKDPRKKKKGKEAGP-----------GAGLPPPRAPALPSEARAPHAS 2080
Query: 308 SACAAPSQEAQ 318
S AA +A+
Sbjct: 2081 SLTAAKRSKAK 2091
Score = 35.8 bits (81), Expect = 0.055
Identities = 71/284 (25%), Positives = 99/284 (34%), Gaps = 67/284 (23%)
Query: 103 VEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSP-KAEDGATPSPSNETPKKKKKRFSFK 161
++ A A+ + P P A+G A S P + P E P+++
Sbjct: 1099 LQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEP------ 1152
Query: 162 KSFKLSGFSFKKNKKEAGEG--------GEAEAPAAEG-GKDEAAGGAAAAAAEAGA--A 210
L+ K ++ EG PAAE AGG EA A A
Sbjct: 1153 ----LAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSA 1208
Query: 211 SGEQAAAPGE--EAAAGEEGAAGGDPQEAKPQEAAV--APEKPPASDETKAAEEPSKVE- 265
+G+ A P E + G E P +P AA+ + P + +A EEP +V
Sbjct: 1209 TGQSCAEPSECPDFVEGPEPRVDS-PGRTEPCTAALDLGVQLTPET-LVEAKEEPVEVPV 1266
Query: 266 -----EKKAEEAGASAAA-----------CEAPSAAG--PGAPPEQEAAPA--------- 298
E EE A A C+ P+ G P P QEA P
Sbjct: 1267 AVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEP-QEAVPVLGSTCFLEE 1325
Query: 299 ----------EEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
E+P A + A AA +A+P SP A A+A E
Sbjct: 1326 ASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALE 1369
Score = 35.0 bits (79), Expect = 0.093
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 240 QEAAVAPEKPPAS----DETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEA 295
Q+AA A E ++ + KA E +++EEK ++ G AA + AGPG P +
Sbjct: 918 QQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKR-GLEAAGKAGLATAGPGLLPRKPP 976
Query: 296 APAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
A PA + PS A P + +A + E
Sbjct: 977 GLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLE 1013
Score = 33.1 bits (74), Expect = 0.35
Identities = 38/159 (23%), Positives = 51/159 (32%), Gaps = 7/159 (4%)
Query: 175 KKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDP 234
K + G A+ A GG+ G A ASG + + A E G P
Sbjct: 197 KGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPP 256
Query: 235 QEAKPQEAAVAPEKPPASDETKAAEEPSKVE--EKKAEEAGASAAACEAPSAAGPGAPPE 292
+ A+ +A K AA +PS + A + G A EA A +
Sbjct: 257 RLAERLSPFLAESK-----TKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQ 311
Query: 293 QEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331
E A PS P P+ PPA A
Sbjct: 312 DEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPA 350
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 65.1 bits (157), Expect = 8e-11
Identities = 91/371 (24%), Positives = 112/371 (30%), Gaps = 53/371 (14%)
Query: 3 AQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANG 62
+Q + +AA A R E A++ + N +G A PAA GA A
Sbjct: 31 SQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPG---AAP 87
Query: 63 SAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG------------ASPVEKEAP-A 109
P A + P G P + + A AP A +PV A A
Sbjct: 88 EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147
Query: 110 EGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKL--S 167
G P P G AA AA + P G P P P + S L S
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 168 GFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEE 227
+ G A P K A G GAA+ AAP AA
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLP---KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA 264
Query: 228 GAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGP 287
A P P PA T A P + AGA+ A AP+A GP
Sbjct: 265 APAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA--PAPAAGGP 322
Query: 288 ------------------------------GAPPEQEAAPAEEPAAAAASSACAAPSQEA 317
APP + A PA+ AAS Q A
Sbjct: 323 AGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382
Query: 318 QPECSPEAPPA 328
P + PPA
Sbjct: 383 LPSPAAVPPPA 393
Score = 47.8 bits (112), Expect = 1e-05
Identities = 75/274 (27%), Positives = 86/274 (31%), Gaps = 30/274 (10%)
Query: 64 APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEG-EAAEPGSPTAA 122
AP + AAAG A + G PA A AGA P APAEG A P P A
Sbjct: 44 APRTPEVRAAAAG---ALGNHVVSGSPAGA----AGAGPA---APAEGAPGAAPEPPPA- 92
Query: 123 EGEAASAASSTSSPKAEDGATP-SPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEG 181
G A P P P+ P K R + S +G A
Sbjct: 93 -GRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS---AGSCAPVPAAAAVAA 148
Query: 182 GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGE-----QAAAPGEEAAAGEEGAAGGDPQE 236
G APA G AA AA AG G PG+ A G G
Sbjct: 149 GPEPAPAGPA----KPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204
Query: 237 AKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAA 296
AA + P + A P+ A P P AA
Sbjct: 205 LNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPP----AA 260
Query: 297 PAEEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330
PA AAA AP+ A+P P PP A
Sbjct: 261 PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAA 294
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/136 (28%), Positives = 49/136 (36%), Gaps = 5/136 (3%)
Query: 199 GAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAA 258
G+ + A AA A E A GA G P AA A PA AA
Sbjct: 27 GSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAA 86
Query: 259 EEPSKVEEKKAEEAGASAAACEAPS----AAGPGAPPEQEAAPAEEPAAAAASSACAAPS 314
EP + G +P AGP APP + P E +A + + AA +
Sbjct: 87 PEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGP-APPAAKLRPPPEGSAGSCAPVPAAAA 145
Query: 315 QEAQPECSPEAPPAEA 330
A PE +P P A
Sbjct: 146 VAAGPEPAPAGPAKPA 161
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/137 (29%), Positives = 55/137 (40%), Gaps = 15/137 (10%)
Query: 2 GAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQAN 61
G + A AAA+ G A A +P+ A G G V+G P AA + ++A
Sbjct: 289 GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG---GPAGVSGQPGPGAAAAAPAPGVKAE 345
Query: 62 GSAPAADKEEPAA---AGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGS 118
PAA A SG AS +A+ P GA P +PA PG+
Sbjct: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTM-----QGALP----SPAAVPPPAPGT 396
Query: 119 PTAAEGEAASAASSTSS 135
PT AA A + + S
Sbjct: 397 PTGLPKGAAGAVTQSLS 413
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 63.9 bits (154), Expect = 2e-10
Identities = 92/372 (24%), Positives = 131/372 (35%), Gaps = 55/372 (14%)
Query: 4 QFSKTAAKGEAAAERPG---EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA 60
Q A G AA PG E A P+KA + G SP E+ +
Sbjct: 180 QVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSR--------GGYSPPPEET---MPFEL 228
Query: 61 NGSAPAADKEEPAA----AGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEP 116
+G D P A +S AA A P A A P+ A G ++
Sbjct: 229 DGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPG-AIGSPSQE 287
Query: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKS--FKLSGFSFKKN 174
+ +S S P E G+ P+ ++TP K+SG K+
Sbjct: 288 AVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRE 347
Query: 175 KKE----------------AGEGGEAEAP------AAEGGKDEAAGGAAAAAAEAGAASG 212
+ E A EGG+ +P A D AA A AA A+ + +
Sbjct: 348 RAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGAT 407
Query: 213 EQAAAPGEEAAAGEEGAAGGDPQE-AKP-----QEAAVAPEKPPASDETKAAEEPSKVEE 266
+ G A + GA DP A P ++ AP+ P D A + P+ +
Sbjct: 408 PEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDA 467
Query: 267 KKAEEAGASAAACE------APSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPE 320
A EA A+ AA E AP+A GAP A+ A+SA A +
Sbjct: 468 GAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIH 527
Query: 321 CSPEAPPAEAAE 332
P +P +AA+
Sbjct: 528 LRPPSPEIQAAD 539
Score = 59.3 bits (142), Expect = 5e-09
Identities = 69/262 (26%), Positives = 100/262 (38%), Gaps = 49/262 (18%)
Query: 24 VASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPS 83
V+ +P K E V+ AAE + G P+ PAA GAAS
Sbjct: 339 VSGAPDKRERAERPPVEEE------AAEMEGAADAAEGGKVPSPGYGSPAA---GAASAD 389
Query: 84 AAEKGEPAAAAAPEAGASPVEKE---APAEGE----AAEPGSPTAAEGEAASAASSTSSP 136
A + PAA A P++GA+P + + APA+ + AA+P S G A +A + S
Sbjct: 390 TAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDS-----GAAPAAPADPDSG 444
Query: 137 KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEA 196
A D S P + G EAPAA +
Sbjct: 445 AAPDAPADPDSGAAPDAPA---------------------DPDAGAAPEAPAAPAAAETR 483
Query: 197 AGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETK 256
A A AA +AGA + A+A AA AA P ++ + P P E +
Sbjct: 484 AAHVAPAAPDAGAPTAPAASA---TRAAQVRRAASAAPASGARRKIHLRPPSP----EIQ 536
Query: 257 AAEEPSKVEEKKAEEAGASAAA 278
AA+ P+ + + G S ++
Sbjct: 537 AADPPTPRPTRASAWRGKSESS 558
Score = 54.7 bits (130), Expect = 1e-07
Identities = 79/276 (28%), Positives = 107/276 (38%), Gaps = 51/276 (18%)
Query: 45 ASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPA-AAAAPE----AG 99
+SP SG E+ GSAPA + P SP A G P + AP+ A
Sbjct: 298 SSPWMEISGPPFEI---GSAPAGVDDTPV----NMDSPPIALDGPPIKVSGAPDKRERAE 350
Query: 100 ASPVEKEAP--------AEG-EAAEPGSPTAAEGEAASAASSTSSPKA----EDGATPS- 145
PVE+EA AEG + PG + A G A++ ++ ++P A + GATP
Sbjct: 351 RPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPED 410
Query: 146 PSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAA 205
P + T +F A + APAA D A A A
Sbjct: 411 PDSGTAPADPDSGAF-----------------AADPDSGAAPAAPADPDSGAAPDAPADP 453
Query: 206 EAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVE 265
++GAA A A + AA E AA P A+ + A VAP P A T A ++
Sbjct: 454 DSGAAP--DAPADPDAGAAPEAPAA---PAAAETRAAHVAPAAPDAGAPTAPAASATRAA 508
Query: 266 EKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEP 301
+ + ASAA PP E A+ P
Sbjct: 509 QVRR---AASAAPASGARRKIHLRPPSPEIQAADPP 541
Score = 47.8 bits (112), Expect = 1e-05
Identities = 68/290 (23%), Positives = 90/290 (31%), Gaps = 44/290 (15%)
Query: 17 ERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAG 76
E PG AA + PS A E E E + A E +
Sbjct: 32 EAPGAAAPGAGPSPAEEMET--------------EPPHNEPIPVENDGEACGPPEVSRPN 77
Query: 77 SGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEG----EAAEPGSPTAAEGEAASAASS 132
+P+ E G + + P A P E E P+ G +PG P+ + +
Sbjct: 78 FQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPA 137
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
P A GA P +P + + F F + + + P
Sbjct: 138 LMEPGAFSGARPGLGGYSPPPE----------EAMPFEFDQPAQRGCSQLLLQVP----- 182
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQE---AAVAPEKP 249
D A GG AA QA P A AG G P+E P E + P
Sbjct: 183 -DLAPGGPGAAGVPGAPPEEPQALRP---AKAGSRGGYSPPPEETMPFELDGEGFGDDSP 238
Query: 250 P--ASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGA--PPEQEA 295
P S + S+ A A A AP PGA P QEA
Sbjct: 239 PPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEA 288
Score = 44.7 bits (104), Expect = 1e-04
Identities = 67/291 (23%), Positives = 92/291 (31%), Gaps = 46/291 (15%)
Query: 62 GSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE---------KEAPAEGE 112
G+ + ++ P G P G AAAP AG SP E + P E +
Sbjct: 9 GNNMSGQRDIPPEIGEQPEQPPLEAPG----AAAPGAGPSPAEEMETEPPHNEPIPVEND 64
Query: 113 AAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETP--KKKKKRFSFKKSFKLSGFS 170
G P + + A +P P P ++ F + + GF
Sbjct: 65 GEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFP 124
Query: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA-------------- 216
+ G P A G GG + EA +Q A
Sbjct: 125 SGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDL 184
Query: 217 APGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE----------EPSKVEE 266
APG AAG GA +PQ +P +A P +ET E P +
Sbjct: 185 APGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSR 244
Query: 267 KKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEA 317
A+ G+S A A S+A PA A +PSQEA
Sbjct: 245 VIAQVDGSSQFAAVAASSA-------VRLTPAANAPPLWVPGAIGSPSQEA 288
Score = 38.9 bits (89), Expect = 0.006
Identities = 49/175 (28%), Positives = 70/175 (40%), Gaps = 42/175 (24%)
Query: 2 GAQFSKTAAKGEAAAER-PGEAAVASSPSKANGQ---ENGHVKVNGD-----ASPAAAES 52
GA + TAA+ AA P A P ++G + D A+PA +S
Sbjct: 384 GAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDS 443
Query: 53 GAKEELQAN---GSAPAADKEE-----------PAAAGSGAA--SPSAAEKGEPAAAAAP 96
GA + A+ G+AP A + PAAA + AA +P+A + G P A AA
Sbjct: 444 GAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAAS 503
Query: 97 EAGASPVEKEA---PAEG--------------EAAEPGSPTAAEGEAASAASSTS 134
A+ V + A PA G +AA+P +P A S +S
Sbjct: 504 ATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRPTRASAWRGKSESS 558
Score = 33.5 bits (75), Expect = 0.27
Identities = 42/173 (24%), Positives = 55/173 (31%), Gaps = 39/173 (22%)
Query: 195 EAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAP-------- 246
EA G AA A + A E E +G A G P+ ++P + P
Sbjct: 32 EAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGAH 91
Query: 247 ---EKPPASDETKAAEEPS------KVEEKKAEEAGASAAACEAPSAAGPGA-------- 289
PP AE+PS +E+ + P+ PGA
Sbjct: 92 GSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGL 151
Query: 290 ----PPEQEAAPAE--EPAAAAASS--------ACAAPSQEAQPECSPEAPPA 328
PP +EA P E +PA S A P P PE P A
Sbjct: 152 GGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQA 204
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 63.5 bits (153), Expect = 2e-10
Identities = 69/330 (20%), Positives = 126/330 (38%), Gaps = 22/330 (6%)
Query: 2 GAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQAN 61
G K A + PG+AA +S S ++ +E+ D + G K + +A
Sbjct: 99 GPPAKKAAVPAKRVGLPPGKAAAKASESSSS-EESSDDDDEEDQKKQPVQKGVKPQAKAA 157
Query: 62 GSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTA 121
K P A S + ++ + EP P+ V+ + A + A +P
Sbjct: 158 -------KAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPAR-AAPKI 209
Query: 122 AEGEAASAASSTSSPKAEDGATPSPSNETPKKK--KKRFSFKKSFKLSGFSFKKNKKEAG 179
A G+AAS++SS+SS + D + + TPKK KK+ K K + +K+
Sbjct: 210 ANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSED 269
Query: 180 EGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP 239
+ E + K++ ++ A P ++A ++ + +
Sbjct: 270 SSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDES 329
Query: 240 QEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAE 299
++ +KPP TKA + + A++A E+ S + E + AP++
Sbjct: 330 DSSSEEEKKPP----TKAVVSKATTKPPPAKKAA------ESSSDSSDSDSSEDDEAPSK 379
Query: 300 EPAAAAASSACAAPSQEAQPECSPEAPPAE 329
PA +S+ P P A P +
Sbjct: 380 -PAGTTKNSSNKPAVTTKSPAVKPAAAPKQ 408
Score = 59.7 bits (143), Expect = 4e-09
Identities = 67/306 (21%), Positives = 126/306 (41%), Gaps = 40/306 (13%)
Query: 34 QENGHV--KVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPA 91
Q NG V K AS + +E ++EE + G P A K AA P+ P
Sbjct: 69 QANGPVAKKAKKKASSSDSEDSSEEEEEVQG--PPAKK---------AAVPAKRVGLPPG 117
Query: 92 AAAAPEAGASPVEKEAPAEGEAAEPGSPT--AAEGEAASAASSTSSPKAEDGATPSPSNE 149
AAA + +S E+ + + E + P + +A +A + K+ D + S S +
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Query: 150 TPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGA 209
P K +K K++ + K K + A AP GK ++ ++++++ +
Sbjct: 178 EPPKNQKP-------KITPVTVKAQTKAPPKPARA-APKIANGKAASSSSSSSSSSSSDD 229
Query: 210 ASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKA 269
+ E+AAA ++ ++ A P +AA P + +S E +++E + ++
Sbjct: 230 SEEEKAAATPKKTVPKKQVVAKA------PVKAATTPTRKSSSSEDSSSDEEEEQKKPMK 283
Query: 270 EEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEA---- 325
+ G + S P APP +++ + P A S+++ E +
Sbjct: 284 NKPGPYS------SVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEK 337
Query: 326 -PPAEA 330
PP +A
Sbjct: 338 KPPTKA 343
Score = 59.3 bits (142), Expect = 5e-09
Identities = 71/338 (21%), Positives = 133/338 (39%), Gaps = 34/338 (10%)
Query: 7 KTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGA------------ 54
KT K + A+ P +AA + ++ +++ + P + G
Sbjct: 241 KTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPP 300
Query: 55 KEELQANGSAPAADKEEPAAAGSGAA----SPSAAEKGEPAAAAAPEAGASPVEKEAPAE 110
K+ L A +K++P + ++ S S EK P A +A P + AE
Sbjct: 301 KKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAE 360
Query: 111 GEAAEPGSPTAAEGEAASAASSTSSPKAEDGA--TPSPSNETPKKKKKRFSFKKSFKLSG 168
+ S ++ + EA S + T+ + A T SP+ + K+ + G
Sbjct: 361 SSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQ--------PVGG 412
Query: 169 FSFKKNKKEAGEGGEAEAPAAEGGKDE--AAGGAAAAAAEAGAASGEQAAAPGEEAAAGE 226
+K E E+ ++E K + A A A+A + + A G ++ +
Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD 472
Query: 227 EGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGAS----AAACEAP 282
++ + +E K ++AV +KP A +P+ ++ KAE + +S ++ E
Sbjct: 473 SDSSSSEEEEEKTSKSAVK-KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEE 531
Query: 283 SAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPE 320
G G+P Q A A +A A + AA + E + E
Sbjct: 532 KLKGKGSPRPQ-APKANGTSALTAQNGKAAKNSEEEEE 568
Score = 58.5 bits (140), Expect = 8e-09
Identities = 71/326 (21%), Positives = 136/326 (41%), Gaps = 44/326 (13%)
Query: 22 AAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAAS 81
A V +ANG K +S + S +EE+Q P A K AA
Sbjct: 61 AKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQ----GPPAKK---------AAV 107
Query: 82 PSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT--AAEGEAASAASSTSSPKAE 139
P+ P AAA + +S E+ + + E + P + +A +A + K+
Sbjct: 108 PAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSS 167
Query: 140 DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGG 199
D + S S + P K +K K++ + K K + A AP GK ++
Sbjct: 168 DSDSDSSSEDEPPKNQKP-------KITPVTVKAQTKAPPKPARA-APKIANGKAASSSS 219
Query: 200 AAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259
++++++ + + E+AAA ++ ++ A P +AA P + +S E +++
Sbjct: 220 SSSSSSSSDDSEEEKAAATPKKTVPKKQVVA------KAPVKAATTPTRKSSSSEDSSSD 273
Query: 260 EPSKVEEKKAEEAGASAAACEAPSAAGP----GAPPEQEAAPAEEPAAAAASSACAAPS- 314
E + ++K + ++ PSA P G P ++A ++P ++ S+ + S
Sbjct: 274 EEEE-QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSS 332
Query: 315 --QEAQP-------ECSPEAPPAEAA 331
+E +P + + + PPA+ A
Sbjct: 333 SEEEKKPPTKAVVSKATTKPPPAKKA 358
Score = 52.4 bits (124), Expect = 6e-07
Identities = 65/355 (18%), Positives = 132/355 (37%), Gaps = 40/355 (11%)
Query: 11 KGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE 70
+ +AA P +A + S S ++ ++ +P ++ K + +AP
Sbjct: 153 QAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANG 212
Query: 71 EPAAAGSGAASPSAAEKGEPAAAAAP----------------EAGASPVEKEAPAEG--- 111
+ A++ S ++S S+++ E AAA +A +P K + +E
Sbjct: 213 KAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSS 272
Query: 112 -EAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
E E P + S+ S+P + P + +K++ S + S S S
Sbjct: 273 DEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSS 332
Query: 171 FKKNKK------------------EAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASG 212
++ KK +A E + + DEA A +
Sbjct: 333 SEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPA 392
Query: 213 EQAAAPG-EEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEE 271
+P + AAA ++ GG + +++ + E+ +S+E K + + + K +
Sbjct: 393 VTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAK 452
Query: 272 AGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAP 326
A S A +AP + + + +++ +EE + SA Q+ +P P
Sbjct: 453 AALSLPAKQAPQGSRDSS-SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKP 506
Score = 49.3 bits (116), Expect = 5e-06
Identities = 47/180 (26%), Positives = 80/180 (44%), Gaps = 17/180 (9%)
Query: 11 KGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE 70
K A +P A A+ A G + D+S + S ++EE + + K
Sbjct: 439 KKMVATTKPKATAKAALSLPAKQAPQG----SRDSSSDSDSSSSEEEEEKTSKSAVKKKP 494
Query: 71 EPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAA 130
+ A G+ + P++A+KG+ ++ + + S E+E +G+ GSP A A
Sbjct: 495 QKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGK----GSPR----PQAPKA 546
Query: 131 SSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAE 190
+ TS+ A++G S E ++KKK SG K+ + EA + EAE P A+
Sbjct: 547 NGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSK---SGSLKKRKQNEAAK--EAETPQAK 601
Score = 45.4 bits (106), Expect = 7e-05
Identities = 58/302 (19%), Positives = 115/302 (38%), Gaps = 36/302 (11%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGS--APAADKEEPAAAG 76
P + ++ + P K ++ V+ + D+S + S +E+ + + A K PA
Sbjct: 299 PPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKA 358
Query: 77 SGAASPSA-AEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSS 135
+ ++S S+ ++ E A + AG + PA + P AA + +
Sbjct: 359 AESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418
Query: 136 PKAEDGATPSPSNETPKKKKKRF--------SFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
KA+ ++ S+ + ++K K+ + K + L + +++ ++ +
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSS 478
Query: 188 AAEGGK----------DEAAGGAAA---AAAEAGAASGEQAAAPGEEAAAGEEGAAG-GD 233
E K + AGGAA A+A+ G A +++ + + EE G G
Sbjct: 479 EEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGS 538
Query: 234 PQEAKPQE-----------AAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAP 282
P+ P+ A + ++ KAA SK K + +A E P
Sbjct: 539 PRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETP 598
Query: 283 SA 284
A
Sbjct: 599 QA 600
Score = 43.5 bits (101), Expect = 3e-04
Identities = 59/278 (21%), Positives = 110/278 (39%), Gaps = 17/278 (6%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANG--QENGHVKVNGDASPAAAESGAKEELQANGS 63
+K AA+ + + + +PSK G + + + SPA + A ++ G
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 64 APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPV----EKEAP--AEGEAAEPG 117
K + +++ ++S + + A P+A A K+AP + +++
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 118 SPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKE 177
S ++ E E ++ S+ + +PS KK K S S S ++ +K
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS-DDSSEEEEEKL 533
Query: 178 AGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEA 237
G+G +P + K A G +A A+ G A+ E+ A + G ++
Sbjct: 534 KGKG----SPRPQAPK---ANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKR 586
Query: 238 KPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGAS 275
K EAA E P A + K + + KK E+ +S
Sbjct: 587 KQNEAAKEAETPQAK-KIKLQTPNTFPKRKKGEKRASS 623
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 62.4 bits (150), Expect = 5e-10
Identities = 88/346 (25%), Positives = 133/346 (38%), Gaps = 54/346 (15%)
Query: 8 TAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAA 67
T+ E E E A A+ P A+ + V G P++ + AK E + G
Sbjct: 84 TSESSEEEEEAEAETAKAT-PRLASTNSS----VLGADLPSSMKEKAKAETEKAGKT-GN 137
Query: 68 DKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEA--PAEGEAAEPGSPTAAEGE 125
PA + A S + A +A S E+E PA G AA+PG +A + +
Sbjct: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
Query: 126 AASAASSTSSPKAE------------------------DGATPSPSNETPKKKKKRFSFK 161
++S +S+SS + + GATP+P P K S
Sbjct: 198 SSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP----PGKAGAVASQT 253
Query: 162 KSFKLSGFSFKKNKKEAGEGGEAEAPAAEG-------GKDEAAGGAAAAAAEAGAASGEQ 214
K+ K S ++ E E E PAA+ GK G A+A A E S +
Sbjct: 254 KAGKPEEDS--ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE----SPRK 307
Query: 215 AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGA 274
AAP A G+ G A Q K +E + + + S+E A+ +K K + A
Sbjct: 308 GAAP---APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ--AKPSGKAPQVRAA 362
Query: 275 SAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPE 320
SA A E+P APP + A + + S+E+ +
Sbjct: 363 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 408
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/306 (24%), Positives = 117/306 (38%), Gaps = 49/306 (16%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEE-PAAAGSGA 79
+A SSP+K Q+ G V V A S + EE S+ +AD EE PAA +
Sbjct: 500 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE-----SSDSADSEEAPAAMTAAQ 554
Query: 80 ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAE 139
A P A P+ A P + A + A T A +A +A S S A
Sbjct: 555 AKP---------ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 605
Query: 140 DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGG 199
G T P+ ++ + +E+ E A G+ ++ G
Sbjct: 606 AGGTQRPAEDS----------------------SSSEESDSEEEKTGLAVTVGQAKSVG- 642
Query: 200 AAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259
+ AAS + G+ A G G + K ++ + SD +AA
Sbjct: 643 ---KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 699
Query: 260 EPSKVEEK-KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQ 318
P++V+ K +A A+ AA APSA G + P + AAA + +PS+
Sbjct: 700 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAP-------GKVVTAAAQAKQRSPSKVKP 752
Query: 319 PECSPE 324
P +P+
Sbjct: 753 PVRNPQ 758
Score = 59.3 bits (142), Expect = 5e-09
Identities = 73/336 (21%), Positives = 121/336 (36%), Gaps = 20/336 (5%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
S A + P +A A+SP+ ++ G + + S ++ ES ++EE G A
Sbjct: 576 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE--KTGLAV 633
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
+ + G + S KG AP + E E + E +
Sbjct: 634 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 693
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
+ AA+S + K T + +N + S K + G K A + +
Sbjct: 694 SEEAAASPAQVKTSVKKTQAKANPAAARAP---SAKGTISAPG----KVVTAAAQAKQRS 746
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAA-- 243
+ A A S +A A +A G E +G +E+ +E A
Sbjct: 747 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 806
Query: 244 VAPEKPPA-SDETKAAEEPSKVEEKKAE------EAGASAAACEAPSAAGPGAPPEQEAA 296
+A KP + + +AA P+K +K + G SAA +A G+ E+ +
Sbjct: 807 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDSGSSSEESDS 864
Query: 297 PAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
E PAA ++ P P SP P A A+
Sbjct: 865 DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
Score = 57.0 bits (136), Expect = 2e-08
Identities = 77/323 (23%), Positives = 120/323 (37%), Gaps = 35/323 (10%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78
PG+ + KA QE+ S AA S A+ + + A+ PAAA +
Sbjct: 667 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN---PAAARAP 723
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGE------AAEPGSPTAAEGEAASAASS 132
+A + + G+ AAA SP + + P A P S + A+AA +
Sbjct: 724 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 783
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
+ P+ + G S+E ++ K SG K ++ A E+P +G
Sbjct: 784 QTGPEEDSG-----SSEEESDSEEEAETLAQVKPSG---KTHQIRAALAPAKESP-RKGA 834
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPAS 252
G +AA+AG + ++ E + GE AA Q KP V P + PA
Sbjct: 835 APTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAG 893
Query: 253 D-----ETKAAEEPSKVEEKKAEEAGASAAACE--------APSAAGPGAPPEQEAAPAE 299
+ +AA P K +A E+ A +++ E A PG P
Sbjct: 894 PAATPAQAQAASTPRKA---RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 950
Query: 300 EPAAAAASSACAAPSQEAQPECS 322
P A +S A S + S
Sbjct: 951 HPRIAPKASMAGASSSKESSRIS 973
Score = 56.6 bits (135), Expect = 3e-08
Identities = 75/335 (22%), Positives = 127/335 (37%), Gaps = 48/335 (14%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKA-----NGQENGHVKVNGDASPAAAESGAKEELQA 60
+K + + AA PG+ A + ++A + Q + + + +PA A+ K
Sbjct: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
Query: 61 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 120
SAPA KE P A+P+ K PAAA + E+++ + E ++
Sbjct: 361 AASAPA--KESPRK----GAAPAPPRKTGPAAA---QVQVGKQEEDSRSSSEESDSDREA 411
Query: 121 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE 180
A AA SP+ + +T + G+
Sbjct: 412 LAAMNAAQVKPLGKSPQVKPAST--------------------MGMGPLGKGAGPVPPGK 451
Query: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGE-------EGAAGGD 233
G A A G +E + ++ ++++ A AP +E + G A G
Sbjct: 452 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 511
Query: 234 PQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQ 293
PQ+A P V EKP D ++++EE S + +EEA A+ A +A A P+
Sbjct: 512 PQKAGPVAVQVKAEKP--MDNSESSEESS--DSADSEEAPAAMTAAQAKPAL---KIPQT 564
Query: 294 EAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
+A P + A+A A +A + PA
Sbjct: 565 KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 599
Score = 54.7 bits (130), Expect = 1e-07
Identities = 80/321 (24%), Positives = 122/321 (38%), Gaps = 21/321 (6%)
Query: 15 AAERPG--EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEP 72
AA +PG A A S S+ + V AS + A A P
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPP 243
Query: 73 AAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASS 132
AG+ AS + A K E + ++ E +S E+E PA + + A++A +
Sbjct: 244 GKAGA-VASQTKAGKPEEDSESSSEE-SSDSEEETPAAKALLQAKASGKTSQVGAASAPA 301
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
SP+ GA P+P +T K + K+ S + + +E EA A A G
Sbjct: 302 KESPR--KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-----EAPAQAKPSG 354
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPAS 252
K A+A A E S + AAP A + G A Q K +E + + + S
Sbjct: 355 KAPQVRAASAPAKE----SPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEESDS 407
Query: 253 D-ETKAAEEPSKVEE-KKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAA-SSA 309
D E AA ++V+ K+ + ++ P G G P + PA A
Sbjct: 408 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 467
Query: 310 CAAPSQEAQPECSPEAPPAEA 330
+ S+E+ E P A A
Sbjct: 468 SESSSEESSDSSDGEVPTAVA 488
Score = 49.7 bits (117), Expect = 4e-06
Identities = 69/299 (23%), Positives = 107/299 (35%), Gaps = 38/299 (12%)
Query: 13 EAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSA---PAAD 68
E AAE + VA S S +G G N AS A + + + + +A P
Sbjct: 1109 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1168
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA------------AEP 116
+E +G SP K E A+ P+ P + + +P
Sbjct: 1169 QEAKPQQAAGMLSPKTGGK-EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1227
Query: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKK----KKKRFSFKKSFKLSGFSFK 172
A+ +A+ T + E + E+ +K +K++ S + + S K
Sbjct: 1228 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1287
Query: 173 KNKKEAGEGGEAEAPA--------AEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAA 224
K K AGEGGEA + +D+A+G + S P EE
Sbjct: 1288 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1347
Query: 225 GEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPS 283
G GGD K ++ EK + K E+ +EKK + AS E+PS
Sbjct: 1348 GMGTVEGGDQSNPKSKK-----EKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPS 1397
Score = 43.1 bits (100), Expect = 3e-04
Identities = 61/294 (20%), Positives = 103/294 (35%), Gaps = 17/294 (5%)
Query: 25 ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSA 84
A+SP + Q G K+ P E+Q AP + + ++ S + S
Sbjct: 1032 ATSPQSTSVQAKGTNKLRKPKLP---------EVQQATKAPESSDDSEDSSDSSSGSEED 1082
Query: 85 AEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATP 144
E + A +A G +P E E AAE ++E + + + S S G TP
Sbjct: 1083 GEGPQGAKSAHTLVGPTPSRTETLVEETAAE-----SSEDDVVAPSQSLLSGYMTPGLTP 1137
Query: 145 SPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAA 204
+ S + K S S L+ K+EA A + + G EAA G
Sbjct: 1138 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK 1197
Query: 205 AEAGAASGEQAAAPGEEAAAGEEGAAGGDP---QEAKPQEAAVAPEKPPASDETKAAEEP 261
+ A + G P EA+ Q + V E K +
Sbjct: 1198 SRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT 1257
Query: 262 SKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQ 315
+K +K E+ + + P+A P + +++ E A+ + + S+
Sbjct: 1258 TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSK 1311
Score = 33.1 bits (74), Expect = 0.35
Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 24/161 (14%)
Query: 29 SKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKG 88
S G E+ K++GD PAA +K+ K++ A G AS S +
Sbjct: 1261 SSRKGWESRKRKLSGD-QPAARTPRSKK------------KKKLGAGEGGEASVSPEKTS 1307
Query: 89 EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT-----------AAEGEAASAASSTSSPK 137
+ A AS KE +G G+ EG S S K
Sbjct: 1308 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKK 1367
Query: 138 AEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEA 178
D + KKK K+ S K S S KK KK A
Sbjct: 1368 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1408
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 62.4 bits (150), Expect = 5e-10
Identities = 88/346 (25%), Positives = 133/346 (38%), Gaps = 54/346 (15%)
Query: 8 TAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAA 67
T+ E E E A A+ P A+ + V G P++ + AK E + G
Sbjct: 84 TSESSEEEEEAEAETAKAT-PRLASTNSS----VLGADLPSSMKEKAKAETEKAGKT-GN 137
Query: 68 DKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEA--PAEGEAAEPGSPTAAEGE 125
PA + A S + A +A S E+E PA G AA+PG +A + +
Sbjct: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
Query: 126 AASAASSTSSPKAE------------------------DGATPSPSNETPKKKKKRFSFK 161
++S +S+SS + + GATP+P P K S
Sbjct: 198 SSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP----PGKAGAVASQT 253
Query: 162 KSFKLSGFSFKKNKKEAGEGGEAEAPAAEG-------GKDEAAGGAAAAAAEAGAASGEQ 214
K+ K S ++ E E E PAA+ GK G A+A A E S +
Sbjct: 254 KAGKPEEDS--ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE----SPRK 307
Query: 215 AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGA 274
AAP A G+ G A Q K +E + + + S+E A+ +K K + A
Sbjct: 308 GAAP---APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ--AKPSGKAPQVRAA 362
Query: 275 SAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPE 320
SA A E+P APP + A + + S+E+ +
Sbjct: 363 SAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSD 408
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/306 (24%), Positives = 117/306 (38%), Gaps = 49/306 (16%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEE-PAAAGSGA 79
+A SSP+K Q+ G V V A S + EE S+ +AD EE PAA +
Sbjct: 500 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE-----SSDSADSEEAPAAMTAAQ 554
Query: 80 ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAE 139
A P A P+ A P + A + A T A +A +A S S A
Sbjct: 555 AKP---------ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 605
Query: 140 DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGG 199
G T P+ ++ + +E+ E A G+ ++ G
Sbjct: 606 AGGTQRPAEDS----------------------SSSEESDSEEEKTGLAVTVGQAKSVG- 642
Query: 200 AAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259
+ AAS + G+ A G G + K ++ + SD +AA
Sbjct: 643 ---KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 699
Query: 260 EPSKVEEK-KAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQ 318
P++V+ K +A A+ AA APSA G + P + AAA + +PS+
Sbjct: 700 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAP-------GKVVTAAAQAKQRSPSKVKP 752
Query: 319 PECSPE 324
P +P+
Sbjct: 753 PVRNPQ 758
Score = 59.3 bits (142), Expect = 5e-09
Identities = 73/336 (21%), Positives = 121/336 (36%), Gaps = 20/336 (5%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP 65
S A + P +A A+SP+ ++ G + + S ++ ES ++EE G A
Sbjct: 576 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE--KTGLAV 633
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGE 125
+ + G + S KG AP + E E + E +
Sbjct: 634 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 693
Query: 126 AASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAE 185
+ AA+S + K T + +N + S K + G K A + +
Sbjct: 694 SEEAAASPAQVKTSVKKTQAKANPAAARAP---SAKGTISAPG----KVVTAAAQAKQRS 746
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAA-- 243
+ A A S +A A +A G E +G +E+ +E A
Sbjct: 747 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 806
Query: 244 VAPEKPPA-SDETKAAEEPSKVEEKKAE------EAGASAAACEAPSAAGPGAPPEQEAA 296
+A KP + + +AA P+K +K + G SAA +A G+ E+ +
Sbjct: 807 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDSGSSSEESDS 864
Query: 297 PAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
E PAA ++ P P SP P A A+
Sbjct: 865 DGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900
Score = 57.0 bits (136), Expect = 2e-08
Identities = 77/323 (23%), Positives = 120/323 (37%), Gaps = 35/323 (10%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78
PG+ + KA QE+ S AA S A+ + + A+ PAAA +
Sbjct: 667 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN---PAAARAP 723
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGE------AAEPGSPTAAEGEAASAASS 132
+A + + G+ AAA SP + + P A P S + A+AA +
Sbjct: 724 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 783
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
+ P+ + G S+E ++ K SG K ++ A E+P +G
Sbjct: 784 QTGPEEDSG-----SSEEESDSEEEAETLAQVKPSG---KTHQIRAALAPAKESPR-KGA 834
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPAS 252
G +AA+AG + ++ E + GE AA Q KP V P + PA
Sbjct: 835 APTPPGKTGPSAAQAGKQD-DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAG 893
Query: 253 D-----ETKAAEEPSKVEEKKAEEAGASAAACE--------APSAAGPGAPPEQEAAPAE 299
+ +AA P K +A E+ A +++ E A PG P
Sbjct: 894 PAATPAQAQAASTPRKA---RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 950
Query: 300 EPAAAAASSACAAPSQEAQPECS 322
P A +S A S + S
Sbjct: 951 HPRIAPKASMAGASSSKESSRIS 973
Score = 56.6 bits (135), Expect = 3e-08
Identities = 75/335 (22%), Positives = 127/335 (37%), Gaps = 48/335 (14%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKA-----NGQENGHVKVNGDASPAAAESGAKEELQA 60
+K + + AA PG+ A + ++A + Q + + + +PA A+ K
Sbjct: 301 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
Query: 61 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 120
SAPA KE P A+P+ K PAAA + E+++ + E ++
Sbjct: 361 AASAPA--KESPRK----GAAPAPPRKTGPAAA---QVQVGKQEEDSRSSSEESDSDREA 411
Query: 121 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE 180
A AA SP+ + +T + G+
Sbjct: 412 LAAMNAAQVKPLGKSPQVKPAST--------------------MGMGPLGKGAGPVPPGK 451
Query: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGE-------EGAAGGD 233
G A A G +E + ++ ++++ A AP +E + G A G
Sbjct: 452 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 511
Query: 234 PQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQ 293
PQ+A P V EKP D ++++EE S + +EEA A+ A +A A P+
Sbjct: 512 PQKAGPVAVQVKAEKP--MDNSESSEESS--DSADSEEAPAAMTAAQAKPAL---KIPQT 564
Query: 294 EAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
+A P + A+A A +A + PA
Sbjct: 565 KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 599
Score = 54.7 bits (130), Expect = 1e-07
Identities = 80/321 (24%), Positives = 122/321 (38%), Gaps = 21/321 (6%)
Query: 15 AAERPG--EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEP 72
AA +PG A A S S+ + V AS + A A P
Sbjct: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPP 243
Query: 73 AAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASS 132
AG+ AS + A K E + ++ E +S E+E PA + + A++A +
Sbjct: 244 GKAGA-VASQTKAGKPEEDSESSSEE-SSDSEEETPAAKALLQAKASGKTSQVGAASAPA 301
Query: 133 TSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGG 192
SP+ GA P+P +T K + K+ S + + +E EA A A G
Sbjct: 302 KESPR--KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-----EAPAQAKPSG 354
Query: 193 KDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPAS 252
K A+A A E S + AAP A + G A Q K +E + + + S
Sbjct: 355 KAPQVRAASAPAKE----SPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEESDS 407
Query: 253 D-ETKAAEEPSKVEE-KKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAA-SSA 309
D E AA ++V+ K+ + ++ P G G P + PA A
Sbjct: 408 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 467
Query: 310 CAAPSQEAQPECSPEAPPAEA 330
+ S+E+ E P A A
Sbjct: 468 SESSSEESSDSSDGEVPTAVA 488
Score = 49.7 bits (117), Expect = 4e-06
Identities = 69/299 (23%), Positives = 107/299 (35%), Gaps = 38/299 (12%)
Query: 13 EAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSA---PAAD 68
E AAE + VA S S +G G N AS A + + + + +A P
Sbjct: 1108 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1167
Query: 69 KEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA------------AEP 116
+E +G SP K E A+ P+ P + + +P
Sbjct: 1168 QEAKPQQAAGMLSPKTGGK-EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1226
Query: 117 GSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKK----KKKRFSFKKSFKLSGFSFK 172
A+ +A+ T + E + E+ +K +K++ S + + S K
Sbjct: 1227 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1286
Query: 173 KNKKEAGEGGEAEAPA--------AEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAA 224
K K AGEGGEA + +D+A+G + S P EE
Sbjct: 1287 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1346
Query: 225 GEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPS 283
G GGD K ++ EK + K E+ +EKK + AS E+PS
Sbjct: 1347 GMGTVEGGDQSNPKSKK-----EKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPS 1396
Score = 42.4 bits (98), Expect = 6e-04
Identities = 62/294 (21%), Positives = 103/294 (35%), Gaps = 18/294 (6%)
Query: 25 ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSA 84
A+SP + Q G K+ P E+Q AP + + ++ S + S
Sbjct: 1032 ATSPQSTSVQAKGTNKLRKPKLP---------EVQQATKAPESSDDSEDSSDSSSGSEED 1082
Query: 85 AEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATP 144
E G A +A G +P E E AAE ++E + + + S S G TP
Sbjct: 1083 GE-GPQGAKSAHTLGPTPSRTETLVEETAAE-----SSEDDVVAPSQSLLSGYMTPGLTP 1136
Query: 145 SPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAA 204
+ S + K S S L+ K+EA A + + G EAA G
Sbjct: 1137 ANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK 1196
Query: 205 AEAGAASGEQAAAPGEEAAAGEEGAAGGDP---QEAKPQEAAVAPEKPPASDETKAAEEP 261
+ A + G P EA+ Q + V E K +
Sbjct: 1197 SRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT 1256
Query: 262 SKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQ 315
+K +K E+ + + P+A P + +++ E A+ + + S+
Sbjct: 1257 TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSK 1310
Score = 33.1 bits (74), Expect = 0.35
Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 24/161 (14%)
Query: 29 SKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKG 88
S G E+ K++GD PAA +K+ K++ A G AS S +
Sbjct: 1260 SSRKGWESRKRKLSGD-QPAARTPRSKK------------KKKLGAGEGGEASVSPEKTS 1306
Query: 89 EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT-----------AAEGEAASAASSTSSPK 137
+ A AS KE +G G+ EG S S K
Sbjct: 1307 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKK 1366
Query: 138 AEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEA 178
D + KKK K+ S K S S KK KK A
Sbjct: 1367 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1407
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 61.6 bits (148), Expect = 9e-10
Identities = 70/259 (27%), Positives = 95/259 (36%), Gaps = 36/259 (13%)
Query: 86 EKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPS 145
+K + AAA+ EA PV E E E + E E A +T + ++ + PS
Sbjct: 682 KKKKAPAAASEEAAFPPV-----VEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPS 736
Query: 146 PSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAA 205
P E K +G + K G G P +D A A+
Sbjct: 737 PHTEAAKD-------------TGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPAS 783
Query: 206 EAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAP-------EKPPASDE---- 254
EA A A P A P+E K +E A AP +KPPA++E
Sbjct: 784 EATGAPTPPPAPPSPSAPPPVV------PKEEKEEETAAAPPVEEGEEQKPPAAEELAVD 837
Query: 255 TKAAEEPSKVE-EKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAP 313
T AEEP K E ++AEE A EA A GA ++ A A SS
Sbjct: 838 TGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQD 897
Query: 314 SQEAQPECSPEAPPAEAAE 332
S + + E AE +
Sbjct: 898 SDSSATCSADEVDEAEGGD 916
Score = 55.5 bits (132), Expect = 7e-08
Identities = 86/352 (24%), Positives = 124/352 (35%), Gaps = 72/352 (20%)
Query: 11 KGEAAAERPGEAAVASSPSKANGQENGH------VKVNGDASPAAAESGAKEELQANGSA 64
+ EA + SP ++ G + D P + E++
Sbjct: 720 EAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDI------ 773
Query: 65 PAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG 124
PA + PA+ +GA +P P A +P A V KE E AA +P EG
Sbjct: 774 PAPTEPTPASEATGAPTP-------PPAPPSPSAPPPVVPKEEKEEETAA---APPVEEG 823
Query: 125 EAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEG--- 181
E P AE+ A + E P K + ++ K EA E
Sbjct: 824 E------EQKPPAAEELAVDTGKAEEPVKSECTEEAEEG------PAKGKDAEAAEATAE 871
Query: 182 GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEG----------AAG 231
G +A EGG A ++ A + +S +A +EA G++
Sbjct: 872 GALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPT 931
Query: 232 GDPQEAKPQEAAVAPEKPPASDETK---AAEEP---SKVEEKKAEEAGASAAACEAPSAA 285
GDP+ A +P+KP + K AA P +KV E E+A AP+
Sbjct: 932 GDPR------ANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDA--------APTKP 977
Query: 286 GPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAP-----PAEAAE 332
P APP + E A S+ S+ P EA PA AAE
Sbjct: 978 APPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAE 1029
Score = 54.7 bits (130), Expect = 1e-07
Identities = 71/309 (22%), Positives = 110/309 (35%), Gaps = 38/309 (12%)
Query: 46 SPAAAESGAK-------EELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEA 98
+PAAA A EE++A+G + ++ A + S P AA +
Sbjct: 686 APAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDT 745
Query: 99 GASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRF 158
G + + A + PG PT + + T + +A TP P+ +P
Sbjct: 746 GQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVV 805
Query: 159 SFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAE------GGKDEAAGGAAAAAAEAGAASG 212
++ + + + EG E + PAAE G +E AE G A G
Sbjct: 806 PKEEKEEETAAA-----PPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKG 860
Query: 213 EQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEK-PPASDETKAAEEPSKVEEKKAEE 271
+ A E A A EGA + +E A A P ++ A +V+E AE
Sbjct: 861 KDA----EAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDE--AEG 914
Query: 272 AGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAA------------PSQEAQP 319
+ PS P P A+P + AA P ++A P
Sbjct: 915 GDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAP 974
Query: 320 -ECSPEAPP 327
+ +P APP
Sbjct: 975 TKPAPPAPP 983
>gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]
Length = 274
Score = 61.6 bits (148), Expect = 9e-10
Identities = 57/200 (28%), Positives = 84/200 (42%), Gaps = 26/200 (13%)
Query: 139 EDGATPSPSNETPKKKKKRFSFKKSFK--LSGFSFKKNKKEAGEGGEAEAPAAEGGKDEA 196
+DG P K K + SF+ ++ K KK+ + EAEA KDEA
Sbjct: 58 QDGIKPED-----KAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEA----NKKDEA 108
Query: 197 AGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPE----KPPAS 252
A + G + AAP + E G AG P E K E A E + PAS
Sbjct: 109 P--VADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPAS 166
Query: 253 DETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAA 312
E KA + E+ A+ +PS+ AP ++E A+ PAA A++A
Sbjct: 167 SEEKAGSAET--------ESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTP 218
Query: 313 PSQEAQPECSPEAPPAEAAE 332
+++A + + + PP E E
Sbjct: 219 AAEDAAAKATAQ-PPTETGE 237
Score = 52.4 bits (124), Expect = 6e-07
Identities = 64/222 (28%), Positives = 87/222 (39%), Gaps = 61/222 (27%)
Query: 44 DASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAA---AAPEAGA 100
D +P A K E A A +P G +PS +KGE AA AAP+A A
Sbjct: 106 DEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPA 165
Query: 101 SPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSP--KAEDGATPSPSNETPKKKKKRF 158
S EK +AE E+A+ AS+ +SP KAED +P+ E PK
Sbjct: 166 SSEEKAG-------------SAETESATKASTDNSPSSKAED----APAKEEPK------ 202
Query: 159 SFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAP 218
+A+ PAA AA AA +A A + Q
Sbjct: 203 ------------------------QADVPAAV----TAAAATTPAAEDAAAKATAQPPTE 234
Query: 219 GEEAAAGEEGAAGGDPQEAKPQEAA---VAPEKPPASDETKA 257
E++ EE D E KP+E+A E+ P +D+ A
Sbjct: 235 TGESSQAEENIEAVD--ETKPKESARQDEGKEEEPEADQEHA 274
Score = 48.5 bits (114), Expect = 8e-06
Identities = 55/210 (26%), Positives = 81/210 (38%), Gaps = 25/210 (11%)
Query: 137 KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEA----------GEGGE-AE 185
KA AT ++ +K+ +K + + NKK+ GEG AE
Sbjct: 66 KAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAE 125
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQA---AAPGEEAAAGEEGAAGGDPQEAKPQEA 242
A A G K + G A +E G+ A AAP + A+ EE A + + A
Sbjct: 126 AAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAP-QAPASSEEKAGSAETESATKAST 184
Query: 243 AVAP----EKPPASDETKAAEEPSKVEEKKAEEAGASAAACEA----PSAAGPGAPPEQE 294
+P E PA +E K A+ P+ V A A AA +A P+ G + E+
Sbjct: 185 DNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEEN 244
Query: 295 AAPAEEPAAAAASSACAAPSQEAQPECSPE 324
+E SA +E +PE E
Sbjct: 245 IEAVDE--TKPKESARQDEGKEEEPEADQE 272
Score = 46.6 bits (109), Expect = 3e-05
Identities = 66/253 (26%), Positives = 89/253 (35%), Gaps = 41/253 (16%)
Query: 51 ESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAE 110
+ G K E +A+ AA K + + G EK + AA EA + EAP
Sbjct: 58 QDGIKPEDKAH---KAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANK---KDEAPVA 111
Query: 111 GEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
+ G T A AA +T S E P + ETP ++KK
Sbjct: 112 DGVEKKGEGTTT----AEAAPATGSKPDE----PGKAGETPSEEKKG------------- 150
Query: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAA 230
E E AP A +E AG A +A A++ ++ E+A A EE
Sbjct: 151 ------EGDAATEQAAPQAPASSEEKAGSAETESATK-ASTDNSPSSKAEDAPAKEEPKQ 203
Query: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAP 290
P A AA P A+ + A E +AEE EA P
Sbjct: 204 ADVPA-AVTAAAATTPAAEDAAAKATAQPPTETGESSQAEE------NIEAVDETKPKES 256
Query: 291 PEQEAAPAEEPAA 303
Q+ EEP A
Sbjct: 257 ARQDEGKEEEPEA 269
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 17/134 (12%)
Query: 11 KGEA---AAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAA 67
KGE A P + P KA + K GDA+ QA APA+
Sbjct: 117 KGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATE----------QAAPQAPAS 166
Query: 68 DKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAA 127
+E+ +A + +A+ ++ + + A A P + + PA AA +P A +
Sbjct: 167 SEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAED---- 222
Query: 128 SAASSTSSPKAEDG 141
+AA +T+ P E G
Sbjct: 223 AAAKATAQPPTETG 236
Score = 37.7 bits (86), Expect = 0.014
Identities = 42/139 (30%), Positives = 54/139 (38%), Gaps = 25/139 (17%)
Query: 11 KGEAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSAPAADK 69
+G+AA E+ A ASS KA E K + D SP++ APA K
Sbjct: 151 EGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAE----------DAPA--K 198
Query: 70 EEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG--EAA 127
EEP A AA +AA A AA +A A P E G + AE EA
Sbjct: 199 EEPKQADVPAAVTAAAATTPAAEDAAAKATAQP----------PTETGESSQAEENIEAV 248
Query: 128 SAASSTSSPKAEDGATPSP 146
S + ++G P
Sbjct: 249 DETKPKESARQDEGKEEEP 267
>gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]
Length = 238
Score = 61.6 bits (148), Expect = 9e-10
Identities = 57/200 (28%), Positives = 84/200 (42%), Gaps = 26/200 (13%)
Query: 139 EDGATPSPSNETPKKKKKRFSFKKSFK--LSGFSFKKNKKEAGEGGEAEAPAAEGGKDEA 196
+DG P K K + SF+ ++ K KK+ + EAEA KDEA
Sbjct: 22 QDGIKPED-----KAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEA----NKKDEA 72
Query: 197 AGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPE----KPPAS 252
A + G + AAP + E G AG P E K E A E + PAS
Sbjct: 73 P--VADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPAS 130
Query: 253 DETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAA 312
E KA + E+ A+ +PS+ AP ++E A+ PAA A++A
Sbjct: 131 SEEKAGSAET--------ESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTP 182
Query: 313 PSQEAQPECSPEAPPAEAAE 332
+++A + + + PP E E
Sbjct: 183 AAEDAAAKATAQ-PPTETGE 201
Score = 52.4 bits (124), Expect = 6e-07
Identities = 64/222 (28%), Positives = 87/222 (39%), Gaps = 61/222 (27%)
Query: 44 DASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAA---AAPEAGA 100
D +P A K E A A +P G +PS +KGE AA AAP+A A
Sbjct: 70 DEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPA 129
Query: 101 SPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSP--KAEDGATPSPSNETPKKKKKRF 158
S EK +AE E+A+ AS+ +SP KAED +P+ E PK
Sbjct: 130 SSEEKAG-------------SAETESATKASTDNSPSSKAED----APAKEEPK------ 166
Query: 159 SFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAP 218
+A+ PAA AA AA +A A + Q
Sbjct: 167 ------------------------QADVPAAV----TAAAATTPAAEDAAAKATAQPPTE 198
Query: 219 GEEAAAGEEGAAGGDPQEAKPQEAA---VAPEKPPASDETKA 257
E++ EE D E KP+E+A E+ P +D+ A
Sbjct: 199 TGESSQAEENIEAVD--ETKPKESARQDEGKEEEPEADQEHA 238
Score = 48.5 bits (114), Expect = 8e-06
Identities = 55/210 (26%), Positives = 81/210 (38%), Gaps = 25/210 (11%)
Query: 137 KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEA----------GEGGE-AE 185
KA AT ++ +K+ +K + + NKK+ GEG AE
Sbjct: 30 KAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAE 89
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQA---AAPGEEAAAGEEGAAGGDPQEAKPQEA 242
A A G K + G A +E G+ A AAP + A+ EE A + + A
Sbjct: 90 AAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAP-QAPASSEEKAGSAETESATKAST 148
Query: 243 AVAP----EKPPASDETKAAEEPSKVEEKKAEEAGASAAACEA----PSAAGPGAPPEQE 294
+P E PA +E K A+ P+ V A A AA +A P+ G + E+
Sbjct: 149 DNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEEN 208
Query: 295 AAPAEEPAAAAASSACAAPSQEAQPECSPE 324
+E SA +E +PE E
Sbjct: 209 IEAVDE--TKPKESARQDEGKEEEPEADQE 236
Score = 46.6 bits (109), Expect = 3e-05
Identities = 66/253 (26%), Positives = 89/253 (35%), Gaps = 41/253 (16%)
Query: 51 ESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAE 110
+ G K E +A+ AA K + + G EK + AA EA + EAP
Sbjct: 22 QDGIKPEDKAH---KAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANK---KDEAPVA 75
Query: 111 GEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
+ G T A AA +T S E P + ETP ++KK
Sbjct: 76 DGVEKKGEGTTT----AEAAPATGSKPDE----PGKAGETPSEEKKG------------- 114
Query: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAA 230
E E AP A +E AG A +A A++ ++ E+A A EE
Sbjct: 115 ------EGDAATEQAAPQAPASSEEKAGSAETESATK-ASTDNSPSSKAEDAPAKEEPKQ 167
Query: 231 GGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAP 290
P A AA P A+ + A E +AEE EA P
Sbjct: 168 ADVPA-AVTAAAATTPAAEDAAAKATAQPPTETGESSQAEE------NIEAVDETKPKES 220
Query: 291 PEQEAAPAEEPAA 303
Q+ EEP A
Sbjct: 221 ARQDEGKEEEPEA 233
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 17/134 (12%)
Query: 11 KGEA---AAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAA 67
KGE A P + P KA + K GDA+ QA APA+
Sbjct: 81 KGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATE----------QAAPQAPAS 130
Query: 68 DKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAA 127
+E+ +A + +A+ ++ + + A A P + + PA AA +P A +
Sbjct: 131 SEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAED---- 186
Query: 128 SAASSTSSPKAEDG 141
+AA +T+ P E G
Sbjct: 187 AAAKATAQPPTETG 200
Score = 37.7 bits (86), Expect = 0.014
Identities = 42/139 (30%), Positives = 54/139 (38%), Gaps = 25/139 (17%)
Query: 11 KGEAAAERPGEAAVASSPSKANGQEN-GHVKVNGDASPAAAESGAKEELQANGSAPAADK 69
+G+AA E+ A ASS KA E K + D SP++ APA K
Sbjct: 115 EGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAE----------DAPA--K 162
Query: 70 EEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG--EAA 127
EEP A AA +AA A AA +A A P E G + AE EA
Sbjct: 163 EEPKQADVPAAVTAAAATTPAAEDAAAKATAQP----------PTETGESSQAEENIEAV 212
Query: 128 SAASSTSSPKAEDGATPSP 146
S + ++G P
Sbjct: 213 DETKPKESARQDEGKEEEP 231
>gi|13376611 zinc finger protein 703 [Homo sapiens]
Length = 590
Score = 61.2 bits (147), Expect = 1e-09
Identities = 89/352 (25%), Positives = 128/352 (36%), Gaps = 78/352 (22%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE--EPAAAG 76
P + + S + ANG G K G ++P AA + A L+ G +PA DK +P + G
Sbjct: 105 PPSSKLNSVAAAANGL--GAEKDPGRSAPGAASAAA--ALKQLGDSPAEDKSSFKPYSKG 160
Query: 77 SGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSP 136
SG ++ + + +SP +K AA P P G SA+SS+SSP
Sbjct: 161 SGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACP--PFPPHGAPVSASSSSSSP 218
Query: 137 KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKE-----------AGEGGEAE 185
G +P S+ K + G K +E G GGE
Sbjct: 219 GGSRGGSPHHSD-----------CKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGE-- 265
Query: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAA----PGEE------AAAGEE----GAAG 231
P A GG + A G + A +G A PG ++ G GA
Sbjct: 266 -PGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYA 324
Query: 232 GDPQEAKP---------------QEAAVAPEKPPASDETKAAEEPSKVE----------- 265
G P + P + P KPP+S A PS ++
Sbjct: 325 GYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGG 384
Query: 266 -EKKAEEAGASAAACEAPSAAGP----GAPPEQEAAPAEEPAAAAASSACAA 312
+ G+S + C A AGP G P +PAA ++S+A AA
Sbjct: 385 YHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAA 436
Score = 37.0 bits (84), Expect = 0.024
Identities = 58/249 (23%), Positives = 84/249 (33%), Gaps = 34/249 (13%)
Query: 56 EELQANGSAPAADKEEPAAAGSGAA-SPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAA 114
E LQ S P + E A A + + ++ G+P P + + V A G
Sbjct: 67 EYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPP--PSSKLNSVAAAANGLGAEK 124
Query: 115 EPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKN 174
+PG AA+A AED + SFK K SG +
Sbjct: 125 DPGRSAPGAASAAAALKQLGDSPAED----------------KSSFKPYSKGSGGGDSRK 168
Query: 175 KKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDP 234
+ + ++ D+A +AA G +A ++ G G+ GG P
Sbjct: 169 DSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG--GSRGGSP 226
Query: 235 Q--EAKPQEAAVAPEKPPASDETKAAEEPSKVEE--------KKAEEAGASAAACEAPSA 284
+ K E E K + EP+ V E+GAS E PSA
Sbjct: 227 HHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSA 286
Query: 285 ---AGPGAP 290
AG AP
Sbjct: 287 LVGAGHVAP 295
Score = 35.0 bits (79), Expect = 0.093
Identities = 72/321 (22%), Positives = 99/321 (30%), Gaps = 25/321 (7%)
Query: 25 ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE----EPAAAGSGAA 80
+SSP + G H E K++ PAA EP A G GA
Sbjct: 215 SSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHG-GAE 273
Query: 81 SPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAED 140
S ++ K EP +A +PV P P S G A + S +
Sbjct: 274 SGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPS-QFVP 332
Query: 141 GATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAA--G 198
G PS S + S + G P GG A+ G
Sbjct: 333 GLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLG 392
Query: 199 GAAAAAAEAGAASGEQAAAPG----------EEAAAGEEGAAGGDPQEAKPQEAAVAPEK 248
G++ + A +G A G + AA A P + +
Sbjct: 393 GSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNE 452
Query: 249 P-PASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAAS 307
P P S AA P +EE + A PGA A P +AA+
Sbjct: 453 PLPHSCNWVAASGPCDKRFATSEELLSHLRT----HTALPGAEKLLAAYPGASGLGSAAA 508
Query: 308 SACAAPS--QEAQPECSPEAP 326
+A AA S P +P +P
Sbjct: 509 AAAAAASCHLHLPPPAAPGSP 529
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 61.2 bits (147), Expect = 1e-09
Identities = 71/297 (23%), Positives = 118/297 (39%), Gaps = 29/297 (9%)
Query: 47 PAAAESGAKEELQANGSAPAAD------KEEPAAAGSGAASPSAAEKGEPAAAA-APEAG 99
P +G + + +GS+P+AD +EE AAA A A ++ E AAAA P +
Sbjct: 39 PQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSS 98
Query: 100 ASPVEKEAPAEGEAAEPGSPTAAEGEAASAASS---TSSPKAEDGATPSPSNETPKKKKK 156
EK + + G G +S ++ + E A P P++ + +K+
Sbjct: 99 GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKR 158
Query: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQ-- 214
+ + G ++ +G A+ A+ ++EAA AA A G + ++
Sbjct: 159 KRQQPQRRPAGGTG---QRRGSGSSPSADQQGAQDREEEAA--AAPAPTSRGHRTEKRKP 213
Query: 215 -----AAAPGEEAAAGEEGAAGGDPQEA--KPQEAAVAPEKPPASDETKAAEEPSKVEEK 267
A G G + D Q A + +EAA AP P + +P + + +
Sbjct: 214 QQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAP-APTSRGHRTEKRKPQQPQRR 272
Query: 268 KAEEAGASAAACEAPSAAGPGAPP-EQEAAPAEEPAAAAASSACAAPSQEAQPECSP 323
A G + +PSA GA E+EAA A P +S + Q +C P
Sbjct: 273 PAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAP---TSSGHRTEKRKRLQLQCQP 326
Score = 53.9 bits (128), Expect = 2e-07
Identities = 74/334 (22%), Positives = 128/334 (38%), Gaps = 32/334 (9%)
Query: 9 AAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAAD 68
AA + A +R EAA A P+ + + ++ PA G + + + S+P+AD
Sbjct: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPA----GGTGQRRGSRSSPSAD 131
Query: 69 K-------EEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTA 121
+ EE AAA + EK + AG + + + + A + G+
Sbjct: 132 QQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDR 191
Query: 122 AEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEG 181
E EAA+A + TS + P P + +S + ++++E E
Sbjct: 192 EE-EAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREE--EA 248
Query: 182 GEAEAPAAEGGKDEA----------AGGAAAAAAEAGAASGEQAAAPG--EEAAAGEEGA 229
A AP + G + E AGG + S +Q A EEAAA
Sbjct: 249 AAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPT 308
Query: 230 AGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGA 289
+ G E K + + + + + + + S ++ A++ AAA P+++G
Sbjct: 309 SSGHRTE-KRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRT 367
Query: 290 PPEQEAAPAEEPAAA-----AASSACAAPSQEAQ 318
+ P PAA + S+ +A Q AQ
Sbjct: 368 EKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQ 401
Score = 45.8 bits (107), Expect = 5e-05
Identities = 58/277 (20%), Positives = 104/277 (37%), Gaps = 58/277 (20%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGH-VKVNGDASPAAAESGAKEELQANGSA 64
S +A + A +R EAA A +P+ GH + P +G + + + S+
Sbjct: 179 SSPSADQQGAQDREEEAAAAPAPT-----SRGHRTEKRKPQQPQCRPAGGTGQRRGSRSS 233
Query: 65 PAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG 124
P+AD++ + + E AAA AP + EK P + + G G
Sbjct: 234 PSADQQR-----------AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRG 282
Query: 125 EAASAAS---STSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEG 181
S ++ + E A P+P++ SG +K K+
Sbjct: 283 SGYSPSADQQGAQDREEEAAAAPAPTS------------------SGHRTEKRKRL---- 320
Query: 182 GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQE 241
+ + A G G +++A + GA E+ E AAA ++G ++ KPQ+
Sbjct: 321 -QLQCQPAGGTGQRRGSGCSSSANQQGAQDREE-----EAAAAPVPTSSGHRTEKRKPQQ 374
Query: 242 AAVAPE----------KPPASDETKAAEEPSKVEEKK 268
P P++D+ +A + +V + K
Sbjct: 375 PQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWK 411
Score = 38.1 bits (87), Expect = 0.011
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 7/134 (5%)
Query: 195 EAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDE 254
+ AGG + S +Q A E A AA + + +EAA AP P +S
Sbjct: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAP-VPTSSGH 100
Query: 255 TKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPS 314
+ +++ + A G + +PSA +Q A EE AAAA
Sbjct: 101 RTEKRKRLQLQCQPAGGTGQRRGSRSSPSA------DQQRAQDREEEAAAAPVPTSRGHR 154
Query: 315 QEAQPECSPEAPPA 328
E + P+ PA
Sbjct: 155 TEKRKRQQPQRRPA 168
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/155 (21%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 182 GEAEAPAAE--GGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP 239
G +P+A+ G +D AAA AA+ A + EEAAA + G E K
Sbjct: 52 GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE-----EEAAAAPVPTSSGHRTE-KR 105
Query: 240 QEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAE 299
+ + + + + + + ++++A++ AAA P++ G + P
Sbjct: 106 KRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQR 165
Query: 300 EPAAAA----ASSACAAPSQEAQPECSPEAPPAEA 330
PA S + + Q+ + EA A A
Sbjct: 166 RPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 200
Score = 35.8 bits (81), Expect = 0.055
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 47/190 (24%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPS-------KANGQENGHVKVNGDA-------SPAAAE 51
S +A + A +R EAA A +P+ K Q+ G SP+A +
Sbjct: 232 SSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQ 291
Query: 52 SGAKEELQANGSAPAADKE--------------EPAAA-----GSGAASPSAAEKG---- 88
GA++ + +APA +PA GSG +S SA ++G
Sbjct: 292 QGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSS-SANQQGAQDR 350
Query: 89 --EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSP 146
E AAA P + EK P + + P A G+ S SSP A+
Sbjct: 351 EEEAAAAPVPTSSGHRTEKRKPQQPQR----RPAAGTGQ---RRGSGSSPSADQQRAQDR 403
Query: 147 SNETPKKKKK 156
E K KK+
Sbjct: 404 EEEVRKWKKR 413
>gi|154146231 DMRT-like family A2 [Homo sapiens]
Length = 542
Score = 61.2 bits (147), Expect = 1e-09
Identities = 75/287 (26%), Positives = 107/287 (37%), Gaps = 51/287 (17%)
Query: 62 GSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTA 121
GS AAD G GA +P A G A A EA + +A PGSP
Sbjct: 158 GSVCAAD-----GGGPGAGAP-AGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLP 211
Query: 122 AEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFK-LSGFSFKKNKKEAGE 180
+ P + DGA P +P+ + S + SG + KEAG
Sbjct: 212 PPVK----------PLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGG 261
Query: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAAS----GEQAAAPGEEAAAGEEGAAGGDPQE 236
A GG++++ G A+ +E+G+ + GE A APG +G P++
Sbjct: 262 SCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSG--------PRQ 313
Query: 237 AKPQE--AAVAPEKPPASDETK----AAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAP 290
P + V P E + +E+ G AA GP AP
Sbjct: 314 RTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGL------GPAAP 367
Query: 291 PEQEAA----------PAEEPAAAAASSACAAPSQEAQPECSPEAPP 327
P++ A P+ AAAAA++A P A + P APP
Sbjct: 368 PDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPP 414
Score = 33.9 bits (76), Expect = 0.21
Identities = 27/89 (30%), Positives = 36/89 (40%)
Query: 60 ANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSP 119
A G PAA ++ A + AA + + + AAAAA AG + A A P
Sbjct: 359 AAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRP 418
Query: 120 TAAEGEAASAASSTSSPKAEDGATPSPSN 148
A A A S SS A P+ S+
Sbjct: 419 LLAGAMAPGALGSLSSRSAFSPLQPNASH 447
Score = 31.2 bits (69), Expect = 1.3
Identities = 36/147 (24%), Positives = 52/147 (35%), Gaps = 35/147 (23%)
Query: 18 RPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE------- 70
R + A S P A G G ASP +ESG++ + + +APA
Sbjct: 254 RASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQ 313
Query: 71 -------------------EPAAAGSGAASPSAAE------KGEPAAAAAPEAGASPVEK 105
E G G A E +G AA P A+P +K
Sbjct: 314 RTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGP---AAPPDK 370
Query: 106 EAPAEGEAAEPGSPTAAEGEAASAASS 132
A AA+ P+ + AA+AA++
Sbjct: 371 AAVGAAAAADDAWPSRVDAAAAAAAAA 397
Score = 30.4 bits (67), Expect = 2.3
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
Query: 42 NGDASPAAAESGAKEELQANGSAPAA-------DKEEPAAAGS-GAASPSAAEKGEPAAA 93
NGD + A+ +A GS P + +++ P +A G+ S S A+K E AA
Sbjct: 241 NGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAA 300
Query: 94 AAPEAG 99
AP G
Sbjct: 301 PAPGLG 306
Score = 29.6 bits (65), Expect = 3.9
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 54 AKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA 113
A + A G+A AAD P+ + AA+ +AA G P A +AG + P A
Sbjct: 366 APPDKAAVGAAAAADDAWPSRVDAAAAAAAAA--GGPGLPAPLQAGPAAPPHHRPLLAGA 423
Query: 114 AEPGSPTAAEGEAASA--ASSTSSPKAEDGATP 144
PG+ + +A + + S A+ GA P
Sbjct: 424 MAPGALGSLSSRSAFSPLQPNASHFGADAGAYP 456
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 61.2 bits (147), Expect = 1e-09
Identities = 76/347 (21%), Positives = 118/347 (34%), Gaps = 53/347 (15%)
Query: 4 QFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGS 63
Q S + + A+ + + +P + +E ++V+ + P++ + +
Sbjct: 235 QRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPG 294
Query: 64 APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAE 123
PA P GA + A + A A+ E G P E ++ P +P AE
Sbjct: 295 PPA-----PLPPPGGARARRARLQHSSALTASVEEGG------VPGEDPSSRPATPELAE 343
Query: 124 GEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGE 183
E+A E P P K EA G
Sbjct: 344 PESAPTLRVEPPSPPEGPPNPGPDGG-----------------------KQDGEAPPAGP 380
Query: 184 AEAPAAEGGKD------EAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEA 237
APA + ++ + A A E E A EA + +G P+EA
Sbjct: 381 C-APATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEA 439
Query: 238 KPQEAAV-----APEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGP-GAPP 291
+P + P P E +A EP + + E G + APS P
Sbjct: 440 EPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLK 499
Query: 292 EQEAAPAEEPAAAAASSACAAPSQEAQP------ECSPEAPPAEAAE 332
+ AA +E PAA+ +A +P E P +PE P AE AE
Sbjct: 500 HRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAE 546
Score = 51.2 bits (121), Expect = 1e-06
Identities = 78/292 (26%), Positives = 96/292 (32%), Gaps = 52/292 (17%)
Query: 25 ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGS---GAAS 81
A + S G G + A+P AE + L+ +P P G G A
Sbjct: 317 ALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAP 376
Query: 82 PS-----AAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSP 136
P+ A +K E A PE ASP P EG+ P + AA EA P
Sbjct: 377 PAGPCAPATDKAEEVVCA-PEDVASPFPTAIP-EGDTTPPETDPAATSEA---------P 425
Query: 137 KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEA 196
A DG P PK+ + +E G G A P E +
Sbjct: 426 SARDG----PERSVPKEAEPTPPVLPD------------EEKGPPGPAPEPEREAETEPE 469
Query: 197 AGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETK 256
G A E E + AP A P+ A A E P AS
Sbjct: 470 RG----AGTEPERIGTEPSTAPAPSPPA---------PKSCLKHRPAAASEGPAASPPLA 516
Query: 257 AAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPP--EQEAAPAEEPAAAAA 306
AAE P E A AAA E P A APP + AAP + A
Sbjct: 517 AAESPP--VEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGA 566
Score = 36.6 bits (83), Expect = 0.032
Identities = 77/344 (22%), Positives = 107/344 (31%), Gaps = 80/344 (23%)
Query: 6 SKTAAKGEAAAERPGEAAVASSPSKANG----QENGHVKVNGDASPAAAESGAKEELQAN 61
S A+ RP E A P +G E + G P A+ G ++ +
Sbjct: 577 SSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERG 636
Query: 62 GSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTA 121
P +G AASP+ K AAAAP + PA E P
Sbjct: 637 ----------PQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNP----- 681
Query: 122 AEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEG 181
S++ S K DGA+ K KR+S + + S K +K
Sbjct: 682 ---FPVKLRSTSLSLKYRDGASQE------VKGVKRYSAEVRLERSLTVLPKEEK----C 728
Query: 182 GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP-Q 240
APA G A + G+ A P E ++ P KP
Sbjct: 729 PLGTAPALRG-------------TRAPSDQGKGKARPPEPLSS-------KPPLPRKPLL 768
Query: 241 EAAVAPEKPPASDETKAAEEPSK---VEEKKAEEAGASAAACEAPSAAGPGA-------- 289
++ P +P D EP K EK+ GA + P+A GPGA
Sbjct: 769 QSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSL--PPAATGPGADGQPAPPW 826
Query: 290 --------------PPEQEAAPAEEPAAAAASSACAAPSQEAQP 319
PP QE P + P + +P
Sbjct: 827 ITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEP 870
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 61.2 bits (147), Expect = 1e-09
Identities = 57/248 (22%), Positives = 87/248 (35%), Gaps = 23/248 (9%)
Query: 90 PAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNE 149
P A + A EK EG+ +E G+ + + + + + G NE
Sbjct: 3 PGAVGESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINE 62
Query: 150 TPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEA-------AGGAAA 202
P + S K+ K A +G AE G DE AGG
Sbjct: 63 GPPTE---------------SGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKED 107
Query: 203 AAAEAGAASGE-QAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEP 261
A AE GE + G + G + +P+EA+ +E+ +A EK A ++ E
Sbjct: 108 AEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESG 167
Query: 262 SKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPEC 321
K + ++ A E + Q + EP A A SQ+A E
Sbjct: 168 QKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVED 227
Query: 322 SPEAPPAE 329
+A P E
Sbjct: 228 EAKAEPKE 235
Score = 57.0 bits (136), Expect = 2e-08
Identities = 76/319 (23%), Positives = 117/319 (36%), Gaps = 29/319 (9%)
Query: 12 GEAAAERPGEA--AVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADK 69
G A E G A A+ P +G++ +G ++ E+ +E++ A K
Sbjct: 46 GAPAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGK 105
Query: 70 EEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASA 129
E+ A EK E + G K P E E E + +
Sbjct: 106 EDAEAE----LKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKE 161
Query: 130 ASSTSSPKAE--DGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
A S KA+ D P P ++ K S +++ + S + +K E +AE+
Sbjct: 162 AKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQ 221
Query: 188 AAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPE 247
A +DEA + A G + A +E A E A G P E + Q+ E
Sbjct: 222 KAVV-EDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDV----E 276
Query: 248 KPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAAS 307
K P E A PS EE G E + + G P+ A+ P+A+ +S
Sbjct: 277 KEP---EGGAGVIPSSPEEWPESPTG------EGHNLSTDGLGPDCVASGQTSPSASESS 327
Query: 308 SACAAPSQEAQPECSPEAP 326
PS P+ PE+P
Sbjct: 328 -----PSDV--PQSPPESP 339
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/292 (25%), Positives = 112/292 (38%), Gaps = 32/292 (10%)
Query: 44 DASPAAAESGAKEE--LQANGS--APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG 99
D S A E ++E L +G+ +PAAD E SG +P+ KG A
Sbjct: 10 DCSAEAREKMEQKEGKLSEDGTTVSPAADNPEM----SGGGAPAEETKG----TAGKAIN 61
Query: 100 ASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKK-KKRF 158
P + E AE G +GEA + E G E K+ +K
Sbjct: 62 EGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEE 121
Query: 159 SFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAA- 217
+ S +++G ++ K E E E E+ A + A EA SG++A A
Sbjct: 122 TTVGSQEMTGRK-EETKSEPKEAEEKESTLASEKQK-------AEEKEAKPESGQKADAN 173
Query: 218 ----PGEEAAAGEEGAAGGDPQEA-KPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEA 272
P +A EE A +E + +E + P++ +E KA + + VE++ E
Sbjct: 174 DRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEP 233
Query: 273 GASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPE 324
EA A A ++EA AEE A + QE E PE
Sbjct: 234 KEPDGKEEAKHGAKEEADAKEEAEDAEE-----AEPGSPSEEQEQDVEKEPE 280
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/252 (20%), Positives = 81/252 (32%), Gaps = 43/252 (17%)
Query: 11 KGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE 70
K E +P A + + + V+ + + E+G ++E A D+E
Sbjct: 156 KAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEE 215
Query: 71 EPAAAGSGAASPSA-AEKGEPAAAAAPEAGASPVE--KEAPAEGEAAEPGSPTAAEGEAA 127
A + A AE EP + GA KE + E AEPGSP+ + +
Sbjct: 216 AKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDV 275
Query: 128 SAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAP 187
P+ G PS E P E+P
Sbjct: 276 E-----KEPEGGAGVIPSSPEEWP---------------------------------ESP 297
Query: 188 AAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPE 247
EG G A + ++P + + E + G+ +E P+ AP
Sbjct: 298 TGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPESPSSGEKKEKAPERRVSAPA 357
Query: 248 KP--PASDETKA 257
+P P + KA
Sbjct: 358 RPRGPRAQNRKA 369
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 60.1 bits (144), Expect = 3e-09
Identities = 76/320 (23%), Positives = 109/320 (34%), Gaps = 45/320 (14%)
Query: 45 ASPAAAESGA---KEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGAS 101
A+P E A K +L P + K+ PA + + + KG+P A
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV----TP 1472
Query: 102 PVEKEAPAEGEAAEPGSPTAAEGEAASAASST------SSPKAEDGATPSPSNET----- 150
P KE PA + A SP A A + T SSPK E ATPS +
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK-EVPATPSSRRDPIAPTA 1531
Query: 151 ---PKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEA 207
KK + K++ + KK EAPA K+ ++ A +
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 208 GAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAV--APEKPPASDETKAAEEPSKVE 265
GA S ++ P P+EA A +PEK PA+ K V
Sbjct: 1592 GAPSPKELLIP--------PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT 1643
Query: 266 EKKAEEAGASAAACEA-------------PSAAGPGAPPEQEAAPAEEPAAAAASSACAA 312
+++ S A+ P+ GP A E APA E +
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703
Query: 313 PSQEAQPECSPEAPPAEAAE 332
P + SP P +A+
Sbjct: 1704 PQTKKSSATSPPICPDPSAK 1723
Score = 52.0 bits (123), Expect = 7e-07
Identities = 71/290 (24%), Positives = 95/290 (32%), Gaps = 35/290 (12%)
Query: 65 PAADKEEPAAAG--SGAASPSAAE----KGEPAAAAAPE------AGASPVEKEAPAEGE 112
P + K PAA GA++P AA KG PAA P+ A P K PA
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075
Query: 113 AAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFK 172
+P AA + +T SPK P P TP K + G
Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKG----APMPPAATPPSPKGGLATPPH---KGAPTT 1128
Query: 173 KNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAA---AGEEGA 229
G P +G A A + + G A+ AP AA + + G
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPA--ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186
Query: 230 AGGDPQEAKPQEAAVAPE--------KPPASDETKAAEEPSK---VEEKKAEEAGASAAA 278
A P+ A AA P P + T AA PS + + A + AA
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Query: 279 CEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
GP PP + A + A P + P + PP+
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296
Score = 50.4 bits (119), Expect = 2e-06
Identities = 79/342 (23%), Positives = 103/342 (30%), Gaps = 39/342 (11%)
Query: 9 AAKGEAAAERPGEAAV---ASSPSKANGQENGHVKVNGDASPAAAESGAK--EELQANGS 63
A KG A+ P A A+ PS G K PAA K +
Sbjct: 926 APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW-APTPPAATPPSPKGGPATPSPKG 984
Query: 64 APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAE 123
AP P + G A+PS P A P SP P +P + +
Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK 1044
Query: 124 GEAASAASSTSSPKAEDGATPSPSN--ETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEG 181
G A+ +P PSP TP L G
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATP-------------SLKGAPTPPAATPPSPK 1091
Query: 182 GEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAA--GEEGAAGGDPQEAKP 239
G P+ +G A A + + G A+ AP AA +G P + P
Sbjct: 1092 GGPATPSPKGAPMPPA--ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Query: 240 QEAAVAPEK---------PPASDETKAAEEPSKVE--EKKAEEAGASAAACEAPSAAGPG 288
A P P + T AA PS + + + A PS G
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209
Query: 289 APPEQEAAPAEEPAAAAAS--SACAAPSQEAQPECSPEAPPA 328
A P + AP PAA S A PS + P PP+
Sbjct: 1210 ATPSPKGAPT-TPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Score = 50.1 bits (118), Expect = 3e-06
Identities = 77/301 (25%), Positives = 106/301 (35%), Gaps = 49/301 (16%)
Query: 47 PAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG-ASPVEK 105
P+ A L+ + PAA P G SP A A +P+ G A+P K
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKG-GPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123
Query: 106 EAPAEGEAAEPGSPTAA------EGEAASAASSTSSPKA------EDGATPSPSNETPKK 153
AP AA P SP +G + A++ SPK GA +P+ P
Sbjct: 1124 GAPTT-PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 154 KKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGE 213
K G + K A A P+ +GG A + GA +
Sbjct: 1183 K-------------GGLATPSPKGAPTTPAATPPSPKGG--------LATPSPKGAPTTP 1221
Query: 214 QAAAPGEEAAAGEEGAAGGDPQEAKPQEAAV--APEKPPASDETKAAEEPSKVEEKKAEE 271
A P + G A P+ A AA +P+ PA+ K A P +
Sbjct: 1222 AATPPSPKG-----GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
Query: 272 AGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAP-SQEAQPECSPEAPPAEA 330
A+ AP+ A PP + PA P A + A P S P+ SP PP +
Sbjct: 1277 GLATPPHKGAPNPAVV-TPPSPKGGPATSPPKGAPTPPAATPPS----PKGSPGTPPPKG 1331
Query: 331 A 331
A
Sbjct: 1332 A 1332
Score = 48.9 bits (115), Expect = 6e-06
Identities = 75/320 (23%), Positives = 105/320 (32%), Gaps = 38/320 (11%)
Query: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78
P + A +SSP KA + PA S KE A + + +P A +
Sbjct: 1481 PKQVATSSSPKKAPATP---APMGAPTLPAVIPSSPKEV-----PATPSSRRDPIAPTAT 1532
Query: 79 AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKA 138
S P A P A P K+ PA PT E A ++ SSP A
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPA--------IPTPKEAPATPSSKEASSPPA 1584
Query: 139 EDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGK-DEAA 197
TPS P K+ + + KEA P+ E G A
Sbjct: 1585 ---VTPSTYKGAPSPKE--------LLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
Query: 198 GGAAAAAAEAGAASGEQAAAPGE---EAAAGEEGAAGGDPQEAKP---QEAAVAPEKPPA 251
G + ++ + +P + A A+ G P + P +E VAP A
Sbjct: 1634 KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP----A 1689
Query: 252 SDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACA 311
+ T P++ + + + S C PSA P APA SS A
Sbjct: 1690 PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTA 1749
Query: 312 APSQEAQPECSPEAPPAEAA 331
+ P APP A
Sbjct: 1750 KGKDASHSPKGPLAPPESKA 1769
Score = 48.5 bits (114), Expect = 8e-06
Identities = 71/284 (25%), Positives = 103/284 (36%), Gaps = 30/284 (10%)
Query: 69 KEEPAAAGSG-AASPSAAE----KGEPAAAAA--PEAGASPVEKEAPAEGEAAEPGSPTA 121
KE PA S A+SP A KG P+ P A SP KEAP A P SP
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP-PAVTPPSPEK 1626
Query: 122 AEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEG 181
A + TS P SP++ K + ++ K G KK E
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK--GLPAKKGPTALKEV 1684
Query: 182 GEAEAPAA---------EGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGG 232
A AP + +G + + + + +A A A
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744
Query: 233 DPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPS--------- 283
+ AK ++A+ +P+ P A E+KA+ + +K SA+ APS
Sbjct: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804
Query: 284 AAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPP 327
+ P PP+Q+ P+ + S AP+ E E P PP
Sbjct: 1805 SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE--DELLPLIPP 1846
Score = 48.1 bits (113), Expect = 1e-05
Identities = 79/323 (24%), Positives = 105/323 (32%), Gaps = 62/323 (19%)
Query: 22 AAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAA------DKEEPAAA 75
A VASSP + +++G AS A+ G L A+ +P K P
Sbjct: 761 APVASSPKECPTEDSG-------ASATASSKGTLTYL-ADSPSPLGVSVSPQTKRPPTKK 812
Query: 76 GSGAASPSAAEKGEPA----AAAAPEAGAS-PVEKEAPAEGEAAEPGSPTAAEGEAASAA 130
GS P A+ PE S K++PA + P SP +G +A
Sbjct: 813 GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP---KGAPTPSA 869
Query: 131 SSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAE 190
+ SPK G T P ETP F K E PA
Sbjct: 870 VTPLSPK---GVT-LPPKETPTPSVVNLPFPK----------------------EGPATP 903
Query: 191 GGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPP 250
K A +++ + A+ P + G P K A +P+ P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Query: 251 ASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSAC 310
AA PS K A S P AA P +P A P+ P A A
Sbjct: 964 TPP---AATPPSP----KGGPATPSPKGAPTPPAATPPSPKGGPATPS--PKGAPTPPAV 1014
Query: 311 AAPSQEAQPECSP-----EAPPA 328
PS + P +P PPA
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPA 1037
Score = 47.4 bits (111), Expect = 2e-05
Identities = 87/361 (24%), Positives = 112/361 (31%), Gaps = 60/361 (16%)
Query: 11 KGEAAAERPGEAAV---ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANG--SAP 65
KG A P A A+ PS G K +PAA K L AP
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPK-GAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 66 AADKEEPAAAGSGAASPSAAEKGEPAAAAA----PEAG-ASPVEKEAPAEGEAAEP---G 117
P + G A+PS KG P AA P+ G A+P K AP A P G
Sbjct: 1196 TTPAATPPSPKGGLATPSP--KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253
Query: 118 SPTAAEGEAASAASSTSSPKAEDG-------ATPSPSNETPKKKKKRFSFKKSFKLSGFS 170
P + A + + P + G P+P+ TP K G
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK------------GGP 1301
Query: 171 FKKNKKEAGEGGEAEAPAAEG--GKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAG--- 225
K A A P+ +G G G A + G ++ G
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 226 -EEGAAGGDPQEAKPQEA---AVAPEKP--------PASDETKAAEEPSKVEEKKAEEAG 273
G P A P A+ P P P D T A P + KKA
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP--LSPKKAPATP 1419
Query: 274 ASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPEC------SPEAPP 327
+ PS P + + PA +A A PS + P SP+ PP
Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479
Query: 328 A 328
A
Sbjct: 1480 A 1480
Score = 46.6 bits (109), Expect = 3e-05
Identities = 86/353 (24%), Positives = 119/353 (33%), Gaps = 53/353 (15%)
Query: 11 KGEAAAERPGEAAV---ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA---NGSA 64
KG A P A A+ PS G K PAA K L G+
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPK-GAPTPPAATPPSLKGGLATPPHKGAP 1287
Query: 65 PAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGA--SPVEKEAPAEGEAAEP---GSP 119
A P+ G A SP PAA G+ +P K AP P G+P
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Query: 120 TAAEGEAASAASSTSSPKAEDGATP---SPSNE-----TPKKKKK--RFSFKKSFKLSGF 169
T +S T+ P +++G TP +PS++ TP K+ K S
Sbjct: 1348 TLPATTPSSKGGPTT-PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406
Query: 170 SFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGA 229
+ K+A PA ++ AA + AP A G
Sbjct: 1407 VIPLSPKKA--------PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 230 AGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPS--AAGP 287
P +P++PPA + + P K A A+ A AP+ A P
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK--------APATPAPMGAPTLPAVIP 1510
Query: 288 GAPPEQEAAPA--EEPAAAAA------SSACAAPSQEAQPEC----SPEAPPA 328
+P E A P+ +P A A + A AP + P SP+ PA
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563
Score = 42.0 bits (97), Expect = 8e-04
Identities = 68/287 (23%), Positives = 100/287 (34%), Gaps = 15/287 (5%)
Query: 47 PAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKE 106
P A+E+ N AP A SPS G P + G S
Sbjct: 702 PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVD-GISHTSAL 760
Query: 107 APAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATP---SPSNETPKKKKKRFSFKKS 163
AP E PT G +A+A+S + D +P S S +T + K+ S
Sbjct: 761 APVASSPKE--CPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
Query: 164 FKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAA 223
+ S + EA E + + +G KD + A S + A P
Sbjct: 819 TPIGNLSSPVSPVEASFLPE-NSLSFQGSKD-----SPATTHSPTPPSPKGAPTPSAVTP 872
Query: 224 AGEEGAAGGDPQEAKPQEAAVA-PEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAP 282
+G + P + P++ PA+ K A S + ++A A+ A P
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS-MTSSSPKKARATPAPKGIP 931
Query: 283 SAAGP-GAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPA 328
++ P GAP A P A S AP+ A SP+ PA
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978
Score = 36.2 bits (82), Expect = 0.042
Identities = 80/383 (20%), Positives = 124/383 (32%), Gaps = 89/383 (23%)
Query: 21 EAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGA- 79
+AA +SPS + + + ++ +A+ A G + PA+ P S A
Sbjct: 564 QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPI----GKPASSMTSPLGVNSSAS 619
Query: 80 -------ASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASS 132
A P +A ++ P A P+E PA G A PT A+G S ++
Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPA-GVA-----PTTAKG--TSTYTT 671
Query: 133 TSSPKAEDGATPSPSNETPKK------------------------------------KKK 156
T+SP E + +P N K+ +
Sbjct: 672 TASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIP 731
Query: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKD--EAAGGAAAAAAEAG------ 208
+ S +G K + A AP A K+ GA+A A+ G
Sbjct: 732 KSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLA 791
Query: 209 --------AASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEK------------ 248
+ S + P ++ +AG + G P EA+ PE
Sbjct: 792 DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851
Query: 249 ---PPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAA 305
P K A PS V + PS P E A PA P A
Sbjct: 852 TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA--PKQAP 909
Query: 306 ASSACAAPSQEAQPECSPEAPPA 328
A S ++ ++A+ +P+ PA
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPA 932
Score = 32.7 bits (73), Expect = 0.46
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 7/133 (5%)
Query: 195 EAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDE 254
EA A E E A P A + AA G P P + AP++ P S
Sbjct: 4 EATETVPATEQELPQPQAETAVLPMSSALSVT--AALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 255 TKAA--EEPSKVEEKKAE-EAGASAAACEAPSAAGPGAPP--EQEAAPAEEPAAAAASSA 309
+A+ PS + E S++ P P AP P PAA A +S
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 310 CAAPSQEAQPECS 322
AP+ + P S
Sbjct: 122 MIAPTLKGTPSSS 134
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.292 0.111 0.293
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,622,594
Number of Sequences: 37866
Number of extensions: 1038224
Number of successful extensions: 27079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 963
Number of HSP's successfully gapped in prelim test: 2045
Number of HSP's that attempted gapping in prelim test: 9019
Number of HSP's gapped (non-prelim): 12092
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.