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Search of human proteins with 15193488
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15193488 BCL2 binding component 3 isoform 4 [Homo sapiens]
(193 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15193488 BCL2 binding component 3 isoform 4 [Homo sapiens] 402 e-113
gi|187829742 BCL2 binding component 3 isoform 2 [Homo sapiens] 213 6e-56
gi|110832843 TBP-associated factor 4 [Homo sapiens] 45 5e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 45 5e-05
gi|28558973 mediator complex subunit 14 [Homo sapiens] 42 2e-04
gi|33286444 mastermind-like 2 [Homo sapiens] 42 3e-04
gi|11386183 WAS protein family, member 2 [Homo sapiens] 42 3e-04
gi|110431370 espin [Homo sapiens] 41 6e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 41 7e-04
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 41 7e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 40 0.001
gi|154146199 sal-like 3 [Homo sapiens] 40 0.002
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 40 0.002
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 40 0.002
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens] 39 0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.003
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 39 0.004
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 39 0.004
gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens] 38 0.006
gi|62953127 polyhomeotic 1-like [Homo sapiens] 38 0.006
gi|23238226 CDC42 effector protein 1 [Homo sapiens] 38 0.006
gi|208431824 forkhead box I3 [Homo sapiens] 38 0.006
gi|197100900 iroquois homeobox 2 [Homo sapiens] 38 0.006
gi|39930475 iroquois homeobox 2 [Homo sapiens] 38 0.006
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 38 0.006
gi|18079216 CASK interacting protein 1 [Homo sapiens] 37 0.008
gi|239754940 PREDICTED: hypothetical protein [Homo sapiens] 37 0.008
gi|239753673 PREDICTED: hypothetical protein [Homo sapiens] 37 0.008
gi|239748304 PREDICTED: hypothetical protein XP_002346608 [Homo ... 37 0.008
gi|209954781 neurotrophic factor artemin isoform 1 precursor [Ho... 37 0.008
>gi|15193488 BCL2 binding component 3 isoform 4 [Homo sapiens]
Length = 193
Score = 402 bits (1033), Expect = e-113
Identities = 193/193 (100%), Positives = 193/193 (100%)
Query: 1 MARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLC 60
MARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLC
Sbjct: 1 MARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLC 60
Query: 61 APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPT 120
APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPT
Sbjct: 61 APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPT 120
Query: 121 QAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLP 180
QAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLP
Sbjct: 121 QAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLP 180
Query: 181 LPRGHRAPEMEPN 193
LPRGHRAPEMEPN
Sbjct: 181 LPRGHRAPEMEPN 193
>gi|187829742 BCL2 binding component 3 isoform 2 [Homo sapiens]
Length = 131
Score = 213 bits (543), Expect = 6e-56
Identities = 102/102 (100%), Positives = 102/102 (100%)
Query: 92 GPQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLRRMADDLNAQ 151
GPQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLRRMADDLNAQ
Sbjct: 30 GPQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLRRMADDLNAQ 89
Query: 152 YERRRQEEQQRHRPSPWRVLYNLIMGLLPLPRGHRAPEMEPN 193
YERRRQEEQQRHRPSPWRVLYNLIMGLLPLPRGHRAPEMEPN
Sbjct: 90 YERRRQEEQQRHRPSPWRVLYNLIMGLLPLPRGHRAPEMEPN 131
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 44.7 bits (104), Expect = 5e-05
Identities = 44/133 (33%), Positives = 50/133 (37%), Gaps = 13/133 (9%)
Query: 6 QEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPA-AYLCAPTA 64
Q P P L GP P P S G C P AAA A PA A P
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162
Query: 65 PPAVTAALGGSRWPG-GPRSRPRGPRPDGPQPSLS-------LAEQHLESP----VPSAP 112
P A+ A G PG GP P +P GP + + L H +P V + P
Sbjct: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222
Query: 113 GALAGGPTQAAPG 125
AL P AAPG
Sbjct: 223 AALLPLPKPAAPG 235
Score = 42.7 bits (99), Expect = 2e-04
Identities = 38/121 (31%), Positives = 47/121 (38%), Gaps = 17/121 (14%)
Query: 22 PRPFPLGRLVPSAVSCGLCEPGLAAA---PAAPTLLPAAYLCAPTAPPAVTAALGGSRWP 78
P+P G ++ + G P AA PAAP PAA AP PP A L +R P
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA--PAAPAAAPPPPPPAPATL--ARPP 284
Query: 79 GGPRSRPRG----PRPDGPQPSLSLAEQHLESPVPSAPGALAGGP------TQAAPGVRG 128
G P P P P Q S +P P ++G P APGV+
Sbjct: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344
Query: 129 E 129
E
Sbjct: 345 E 345
Score = 30.0 bits (66), Expect = 1.3
Identities = 35/111 (31%), Positives = 39/111 (35%), Gaps = 9/111 (8%)
Query: 16 GLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGS 75
G A P P P P+ VS G PG AAA AP + + A P L S
Sbjct: 307 GSAGAAPAPAPAAG-GPAGVS-GQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAAS 364
Query: 76 RWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGV 126
S GP G PS + P APG G P AA V
Sbjct: 365 GPASTAASMVIGPTMQGALPSPAAVP-------PPAPGTPTGLPKGAAGAV 408
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 44.7 bits (104), Expect = 5e-05
Identities = 55/186 (29%), Positives = 63/186 (33%), Gaps = 18/186 (9%)
Query: 11 PEPVEGLA-RDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVT 69
P PV A PR P S G +PG A AAP P AP APPAV
Sbjct: 137 PAPVAAAAPARAPRAAAAAATAPP--SPGPAQPGPRAQRAAPLAAPPP---APAAPPAVA 191
Query: 70 AALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAP---GALAGGPTQAAPGV 126
G R P + P P PQP +Q P P P GA+ G +
Sbjct: 192 PPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSL 251
Query: 127 RGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPLPRGHR 186
R GA R + E +E R R L +G L LPRG R
Sbjct: 252 REVVRYLGGSGGAGGRLTRGRVQGLLE---EEAAARGR------LERTRLGALALPRGDR 302
Query: 187 APEMEP 192
P
Sbjct: 303 PGRAPP 308
Score = 37.4 bits (85), Expect = 0.008
Identities = 32/86 (37%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 45 AAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWP---GGPRSRPRGPRPDGPQP-SLSLA 100
AAA AAP PA P PPA AA +R P + P P P P P + A
Sbjct: 121 AAAAAAPPPTPA-----PPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA 175
Query: 101 EQHLESPVPSAPGALA--GGPTQAAP 124
P P+AP A+A GP +A P
Sbjct: 176 PLAAPPPAPAAPPAVAPPAGPRRAPP 201
>gi|28558973 mediator complex subunit 14 [Homo sapiens]
Length = 1454
Score = 42.4 bits (98), Expect = 2e-04
Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 10/110 (9%)
Query: 43 GLAAAPAAPTLLPAAYLCAPTAPPAVTAALG-GSRWPGGPRSRPRGPRPDGPQPSLSLAE 101
G++ P A P L P++P + + G WPG P+ GP P P +S A
Sbjct: 1075 GISIGPGASFASPHGTL-DPSSPYTMVSPSGRAGNWPGSPQVS--GPSPAARMPGMSPAN 1131
Query: 102 QHLESPVPSAPGALAGG------PTQAAPGVRGEEEQWAREIGAQLRRMA 145
L SPVP A + G PT P + + WA I L A
Sbjct: 1132 PSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSA 1181
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 42.0 bits (97), Expect = 3e-04
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 80 GPRSRPRGPRPDGPQPSLSLAEQHLE--SPVPSAPGALAGGPTQAAPGVRGEEEQWAREI 137
GP P+ RP P+ S+A L SP+PS P + A Q G W
Sbjct: 375 GPSGSPQ-LRPPSAGPAFSMANSALSTSSPIPSVPQSQA--QPQTGSGASRALPSWQEVS 431
Query: 138 GAQ-LRRMADDLNAQYERRRQEEQQRHRPSPWRVL 171
AQ L+++A N Q R Q+ QQ+H+P+ W L
Sbjct: 432 HAQQLKQIA--ANRQQHARMQQHQQQHQPTNWSAL 464
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 42.0 bits (97), Expect = 3e-04
Identities = 45/164 (27%), Positives = 59/164 (35%), Gaps = 19/164 (11%)
Query: 8 GSSPEPVEGLA---RDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTA 64
GS P P G A P P P+ + P G PG P+ P+ P AP
Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP 366
Query: 65 PPAVTAALGGSRWP--------GGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALA 116
PP AA + P G P P P P P P + A+ P P +
Sbjct: 367 PPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKP 426
Query: 117 GGPTQAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQ 160
A R + R+ G QLRR+ E+R QE++
Sbjct: 427 KSSLPAVSDARSDLLSAIRQ-GFQLRRVE-------EQREQEKR 462
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 41.2 bits (95), Expect = 6e-04
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 24/98 (24%)
Query: 89 RPDGPQPSLSLAEQHLESPVPSAPG--ALAGG------PTQAAPGVRGEEE--------- 131
+PD P PS+S A + SP P A G L G PT APGV+ + E
Sbjct: 687 QPDSPLPSVSPALSPVRSPTPPAAGFQPLLNGSLVPVPPTTPAPGVQLDVEALIPTHDEQ 746
Query: 132 -----QWAREIGAQLRRMADDLNAQYERRRQEEQQRHR 164
+W R++ +R+M + + E+RR+EE++ R
Sbjct: 747 GRPIPEWKRQV--MVRKMQLKMQEEEEQRRKEEEEEAR 782
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 40.8 bits (94), Expect = 7e-04
Identities = 34/96 (35%), Positives = 37/96 (38%), Gaps = 5/96 (5%)
Query: 32 PSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPD 91
PS + P P AP L A L P +PPA + P PR P P
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP--PRVPPLLAAPP 765
Query: 92 ---GPQPSLSLAEQHLESPVPSAPGALAGGPTQAAP 124
P P SL L P P AP ALA P QA P
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Score = 39.7 bits (91), Expect = 0.002
Identities = 34/118 (28%), Positives = 46/118 (38%), Gaps = 12/118 (10%)
Query: 12 EPVEGLARDGPRPFPLGRLV--PSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVT 69
+ + LA P+ PL L+ P L P L PA+ T P L + PP T
Sbjct: 490 QALSSLASHSPQA-PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 70 AALGGSRWPGGPRSRPRGPRPDGPQPS-LSLAEQHLESPVPSAPGALAGGPTQAAPGV 126
A+ P + P P P P L L +P P P ++A P QA P +
Sbjct: 549 AS--------APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598
Score = 37.4 bits (85), Expect = 0.008
Identities = 34/95 (35%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 32 PSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPT--APPAVTAALGGSRWPGGPRSRPRGPR 89
P V L P L P+ P LP + L P APPA+ A P P S P G
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL-ATPPLQALPSPPASFP-GQA 811
Query: 90 PDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAP 124
P P SL ++ L +P P AP LA Q P
Sbjct: 812 PFSPSASLPMSP--LATPPPQAPPVLAAPLLQVPP 844
Score = 35.4 bits (80), Expect = 0.030
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 5/102 (4%)
Query: 41 EPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLA 100
E G AA+P L A + A + PA A G+ PG P P P ++
Sbjct: 919 EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA--PGAPLPWPPATGPGSADGLCTIY 976
Query: 101 EQHLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLR 142
E APGAL GP +PG G + GA R
Sbjct: 977 ETEGPESATPAPGALDPGP---SPGTSGGKAAAGAGAGASSR 1015
Score = 34.7 bits (78), Expect = 0.052
Identities = 35/136 (25%), Positives = 44/136 (32%), Gaps = 18/136 (13%)
Query: 7 EGSSPEPVEGLARDGPRPFPLGRLVP-----SAVSCGLCEPGLAAAPAAPTLLPAAYLCA 61
+G P+ LA P+ P L P S + P +P AP L L A
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663
Query: 62 PTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHL-------------ESPV 108
P +PP P P P P PSL+ + +P
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 723
Query: 109 PSAPGALAGGPTQAAP 124
P AP LA P Q P
Sbjct: 724 PQAPPPLAAPPLQVPP 739
Score = 32.3 bits (72), Expect = 0.26
Identities = 35/113 (30%), Positives = 41/113 (36%), Gaps = 13/113 (11%)
Query: 13 PVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAP-TAPPAVTAA 71
P+E L P P S L P L P P P +P T PP T +
Sbjct: 534 PLENLPSLAPPPL-------QTASAPLTTPHLETPPC-PAPCPLQAPPSPLTTPPPETPS 585
Query: 72 LGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAP 124
+ P P + P P P LS L +P P AP LA P QA P
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLS----PLATPPPQAPPXLALPPLQAPP 634
Score = 31.2 bits (69), Expect = 0.57
Identities = 28/94 (29%), Positives = 32/94 (34%), Gaps = 11/94 (11%)
Query: 32 PSAVSCGLCEPGLAAAPA-APTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRP 90
PSA P LAA P P PA+ +P+A P P P P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP----------PQAPPPLAAPPLQ 736
Query: 91 DGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAP 124
P P S +P P P LA P Q P
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Score = 30.8 bits (68), Expect = 0.75
Identities = 37/146 (25%), Positives = 52/146 (35%), Gaps = 22/146 (15%)
Query: 4 ARQEGSSPEPVEGLARDGP---------------RPFPLGRLVPSAVSCGLCEPGLAAAP 48
+R SS P+ AR GP +P L L P V+ + A P
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 49 AAPTLL----PAAYLCAPTAPPAVTAA-LGGSRWPGGPRSRPRGPRPDGPQ--PSLSLAE 101
+ + L P+ P PP A L + P P + P P P PSL
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358
Query: 102 QHLESPVPSAPGALAGGPTQAAPGVR 127
+P AP ++ P QA P ++
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQ 384
Score = 27.3 bits (59), Expect = 8.3
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 15/135 (11%)
Query: 7 EGSSPEPVE--GLARDGPRPFPLGRLVPSAVSCGLCEPGLAA-APAAPTLLPAAY--LCA 61
+ +SP PV G A RP PLG+ + G A AP L A
Sbjct: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 62 PTAPPAVTAALGGSRWPG--------GPRSRPRGPRPDGPQPSLSLAEQH-LESPVPSAP 112
PT A SR G P +RPR P +GP+ S+S A +H P P+A
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR-PPTEGPRKSVSSASEHSTTEPSPAAR 225
Query: 113 GALAGGPTQAAPGVR 127
+ G P R
Sbjct: 226 RRPSAGGGLQRPASR 240
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 40.8 bits (94), Expect = 7e-04
Identities = 38/115 (33%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 9 SSPE---PVEGLARDGPRPFPLG-RLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTA 64
S PE PVE +AR RP P + P VS G ++P AP L P + +P
Sbjct: 550 SPPETAAPVEDMARRTKRPAPARPTMPPPQVS------GSRSSPPAPPLPPGSG--SPGT 601
Query: 65 PPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGP 119
P A+ L GS P P P PQP+ + + SP P++PG + P
Sbjct: 602 PQALPRRLVGSSLRAPTVPPPLPPTP--PQPARRQSRRSPASPSPASPGPASPSP 654
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/104 (33%), Positives = 43/104 (41%), Gaps = 7/104 (6%)
Query: 24 PFPLGRLVPSAVSCGLCEPGLAAAP---AAPTLLPAAYLCAPTAPPAVTAALGGSRWPGG 80
PFP G P A + + AA P APT PAA L +P PA + G P
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTT-PAATLPSPKGGPATPSLKGA---PTP 1082
Query: 81 PRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAP 124
P + P P+ PS A + PS G LA P + AP
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Score = 35.8 bits (81), Expect = 0.023
Identities = 32/118 (27%), Positives = 40/118 (33%), Gaps = 18/118 (15%)
Query: 11 PEPVEGLARDGPRPFPLG-RLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVT 69
P P GLA P+ P P + GL P AP P P + P PP
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP--- 1259
Query: 70 AALGGSRWPGGPRSRPRGPRPDGPQPSLSLA-EQHLESPVPS--APGALAGGPTQAAP 124
P+ P P P LA H +P P+ P + GGP + P
Sbjct: 1260 -----------PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306
Score = 35.4 bits (80), Expect = 0.030
Identities = 30/117 (25%), Positives = 44/117 (37%), Gaps = 8/117 (6%)
Query: 11 PEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTA 70
P P EG A P+ P + S+ P PA+P+ P APT P A
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS--PKG---APTPPAATPP 948
Query: 71 ALGGSRWPGGPRSRPRGPRPDGPQPS---LSLAEQHLESPVPSAPGALAGGPTQAAP 124
+ G P+ P P P P + + + +P + P + GGP +P
Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Score = 34.7 bits (78), Expect = 0.052
Identities = 35/131 (26%), Positives = 45/131 (34%), Gaps = 17/131 (12%)
Query: 11 PEPVEGLARDGPRPFPLG-RLVPSAVSCGLCEPGLAAAPAAPTLLP---------AAYLC 60
P P GLA P+ P P + GL P AP P P +
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216
Query: 61 APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLA---EQHLESPVPSAPGALAG 117
APT P A + G P+ P P P P A + +P + P +L G
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
Query: 118 G----PTQAAP 124
G P + AP
Sbjct: 1277 GLATPPHKGAP 1287
Score = 33.1 bits (74), Expect = 0.15
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 13/130 (10%)
Query: 11 PEPVEGLARDGPRPFPLG-RLVPSAVSCGLCEPGLAAAPAAPTLLPAA---------YLC 60
P P G A P+ P+ P + GL P AP P P +
Sbjct: 1088 PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG 1147
Query: 61 APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPT 120
APT P A + G P+ P P P P LA + P+ P A P
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPK 1206
Query: 121 --QAAPGVRG 128
A P +G
Sbjct: 1207 GGLATPSPKG 1216
Score = 32.0 bits (71), Expect = 0.34
Identities = 30/120 (25%), Positives = 36/120 (30%), Gaps = 2/120 (1%)
Query: 11 PEPVEGLARDGPRPFPLG-RLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVT 69
P P GLA P+ P P + G P AP P P + PP
Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG 1285
Query: 70 AALGGSRWPGGPRSRPRGPRPDG-PQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGVRG 128
A P P+ P P G P P + SP P P P +G
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Score = 32.0 bits (71), Expect = 0.34
Identities = 33/121 (27%), Positives = 41/121 (33%), Gaps = 16/121 (13%)
Query: 11 PEPVEGLARDGPR--PFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAV 68
P P G A P+ P P PS P AP P + P + PT P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP-KGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 69 TAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGVRG 128
++ GG P S GP P PS H P + P G A P +G
Sbjct: 1354 PSSKGGPTTP----SSKEGPTPPAATPS------HKGGPAMTPPSPKRG---PAIPSPKG 1400
Query: 129 E 129
+
Sbjct: 1401 D 1401
Score = 31.2 bits (69), Expect = 0.57
Identities = 34/130 (26%), Positives = 42/130 (32%), Gaps = 13/130 (10%)
Query: 11 PEPVEGLARDGPRPFPLG-RLVPSAVSCGLCEPGLAAAPAAPTLLPAA---------YLC 60
P P GLA + P P + GL P AP P P +
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 61 APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPT 120
APT P A + G P+ P P P P LA + P+ P A P
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPK 1229
Query: 121 --QAAPGVRG 128
A P +G
Sbjct: 1230 GGLATPSPKG 1239
>gi|154146199 sal-like 3 [Homo sapiens]
Length = 1300
Score = 39.7 bits (91), Expect = 0.002
Identities = 43/131 (32%), Positives = 52/131 (39%), Gaps = 26/131 (19%)
Query: 17 LARDGPRPFPLGRLVPSAVSCGLCE-PGLAAAPAAPTLLPAAYLC--APTAPPAVTAAL- 72
+ R PRP PSA + PGLAA P + PAA + P AP A A
Sbjct: 233 MQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAG-APAAAIAGSGPAAPAAFEGAQP 291
Query: 73 -----GGSRWPGGPRS-----------RPRGPRP-DGPQPSLSLAEQHLESPVPSAPGAL 115
G+ PGGP P P P PQ + S Q +P APG+L
Sbjct: 292 LSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSL 351
Query: 116 AGGPTQAAPGV 126
G AAPG+
Sbjct: 352 LG----AAPGL 358
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 39.7 bits (91), Expect = 0.002
Identities = 44/133 (33%), Positives = 53/133 (39%), Gaps = 18/133 (13%)
Query: 1 MARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLC--EPGLAAAPAAPTLLPAAY 58
++R EGSSP G P P P G V A +P AA P L+
Sbjct: 355 VSRMISEGSSPIRCPGQCLS-PAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMET 413
Query: 59 LCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGG 118
LCAP PPA P PR GP GP LS + +P+ +APG A
Sbjct: 414 LCAP-PPPA----------PAAPRP---GPAQPGPCLFLSNPTRDTITPLWAAPGR-AAR 458
Query: 119 PTQAAPGVRGEEE 131
P +A EEE
Sbjct: 459 PGRACSAACSEEE 471
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 39.7 bits (91), Expect = 0.002
Identities = 44/133 (33%), Positives = 53/133 (39%), Gaps = 18/133 (13%)
Query: 1 MARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLC--EPGLAAAPAAPTLLPAAY 58
++R EGSSP G P P P G V A +P AA P L+
Sbjct: 328 VSRMISEGSSPIRCPGQCLS-PAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMET 386
Query: 59 LCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGG 118
LCAP PPA P PR GP GP LS + +P+ +APG A
Sbjct: 387 LCAP-PPPA----------PAAPRP---GPAQPGPCLFLSNPTRDTITPLWAAPGR-AAR 431
Query: 119 PTQAAPGVRGEEE 131
P +A EEE
Sbjct: 432 PGRACSAACSEEE 444
>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
Length = 1374
Score = 39.3 bits (90), Expect = 0.002
Identities = 38/108 (35%), Positives = 44/108 (40%), Gaps = 12/108 (11%)
Query: 27 LGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPR---- 82
LG SA G C PGL +A L PA L P+ TA+ GG P+
Sbjct: 729 LGLQAASAQEPGCC-PGLPHLCSAQGLAPAPCLVTPSWTE--TASSGGDHPQAEPKLATE 785
Query: 83 ----SRPRGPRPDGPQPSLSLAE-QHLESPVPSAPGALAGGPTQAAPG 125
+ PR P P P PS A E+ P AP AL PT A G
Sbjct: 786 AEGTTGPRLPLPSVPSPSQEGAPLPSEEASAPDAPDALPDSPTPATGG 833
Score = 29.6 bits (65), Expect = 1.7
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 18/88 (20%)
Query: 85 PRGPRPDGPQPSLSLAEQHLESPVP-----------SAPGALAGGPTQAAPGVRGEEEQW 133
P+GP P PS S ++ L +PVP PG L+G Q G G
Sbjct: 1083 PQGPAKVRPGPSPSCSQFFLLTPVPLRSEGNSSEFQGPPGLLSGPAPQKRMGGPGTPR-- 1140
Query: 134 AREIGAQLRRMADDLNAQYERRRQEEQQ 161
A LR L A E R +EE++
Sbjct: 1141 -----APLRLALPGLPAALEGRPEEEEE 1163
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 38.9 bits (89), Expect = 0.003
Identities = 33/107 (30%), Positives = 39/107 (36%), Gaps = 8/107 (7%)
Query: 26 PLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRP 85
PL PSA P L A P + +L P APP+ +A P P + P
Sbjct: 303 PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPP 362
Query: 86 RGPRPDGPQPSLSLAEQHLES--------PVPSAPGALAGGPTQAAP 124
P+L L S P P AP ALA P QA P
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409
Score = 38.5 bits (88), Expect = 0.004
Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 19/124 (15%)
Query: 13 PVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVT--- 69
P+ LA P+ P+A++ L + + P+ P P + +P P+ T
Sbjct: 416 PLSPLATPSPQ-------APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468
Query: 70 ------AALGGSRWPGGPRSRPRGPRPDGPQ---PSLSLAEQHLESPVPSAPGALAGGPT 120
AA P P S P P P P L+ L P P AP ALA P
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 528
Query: 121 QAAP 124
QA P
Sbjct: 529 QALP 532
Score = 35.4 bits (80), Expect = 0.030
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 5/102 (4%)
Query: 41 EPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLA 100
E G AA+P L A + A + PA A G+ PG P P P ++
Sbjct: 650 EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA--PGAPLPWPPATGPGSADGLCTIY 707
Query: 101 EQHLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLR 142
E APGAL GP +PG G + GA R
Sbjct: 708 ETEGPESATPAPGALDPGP---SPGTSGGKAAAGAGAGASSR 746
Score = 33.5 bits (75), Expect = 0.12
Identities = 35/103 (33%), Positives = 40/103 (38%), Gaps = 10/103 (9%)
Query: 22 PRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGP 81
P P + PSA P LAA P P P APPA+ A P P
Sbjct: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP------PQAPPAL-ATPPLQALPSPP 535
Query: 82 RSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAP 124
S P G P P SL ++ L +P P AP LA Q P
Sbjct: 536 ASFP-GQAPFSPSASLPMSP--LATPPPQAPPVLAAPLLQVPP 575
Score = 33.1 bits (74), Expect = 0.15
Identities = 28/106 (26%), Positives = 37/106 (34%), Gaps = 2/106 (1%)
Query: 32 PSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPD 91
PS + P +P AP L L AP +PP P P P P
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468
Query: 92 GPQPSLSLAEQHLESPVPSAP--GALAGGPTQAAPGVRGEEEQWAR 135
PSL+ + P++P A P QA P + Q A+
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514
Score = 32.7 bits (73), Expect = 0.20
Identities = 38/131 (29%), Positives = 51/131 (38%), Gaps = 26/131 (19%)
Query: 9 SSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCA--PTAPP 66
++P P L P P S+++C L P L AP +P+ P+ P PP
Sbjct: 305 ATPSPSAALQSQAPPTLP-ATPHSSSLTCQLATP-LPLAPPSPSAPPSLQTLPSPPATPP 362
Query: 67 A-VTAALGG-------SRWPGGPRSRPRGPRPDGPQPSLSLAEQH-------------LE 105
+ T +LG S P P S P P P P+L+L L
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALPPLQAPPSPPASPPLSPLA 421
Query: 106 SPVPSAPGALA 116
+P P AP ALA
Sbjct: 422 TPSPQAPNALA 432
Score = 27.3 bits (59), Expect = 8.3
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 15/135 (11%)
Query: 7 EGSSPEPVE--GLARDGPRPFPLGRLVPSAVSCGLCEPGLAA-APAAPTLLPAAY--LCA 61
+ +SP PV G A RP PLG+ + G A AP L A
Sbjct: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 62 PTAPPAVTAALGGSRWPG--------GPRSRPRGPRPDGPQPSLSLAEQH-LESPVPSAP 112
PT A SR G P +RPR P +GP+ S+S A +H P P+A
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR-PPTEGPRKSVSSASEHSTTEPSPAAR 225
Query: 113 GALAGGPTQAAPGVR 127
+ G P R
Sbjct: 226 RRPSAGGGLQRPASR 240
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 38.5 bits (88), Expect = 0.004
Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 19/124 (15%)
Query: 13 PVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVT--- 69
P+ LA P+ P+A++ L + + P+ P P + +P P+ T
Sbjct: 377 PLSPLATPSPQ-------APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429
Query: 70 ------AALGGSRWPGGPRSRPRGPRPDGPQ---PSLSLAEQHLESPVPSAPGALAGGPT 120
AA P P S P P P P L+ L P P AP ALA P
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489
Query: 121 QAAP 124
QA P
Sbjct: 490 QALP 493
Score = 36.6 bits (83), Expect = 0.014
Identities = 42/145 (28%), Positives = 53/145 (36%), Gaps = 28/145 (19%)
Query: 4 ARQEGSSPEPVEGLARDGP---------------RPFPLGRLVPSAVSCGLCEPGLAAAP 48
+R SS P+ AR GP +P L L P V+ P AAP
Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT----PPRKDAAP 285
Query: 49 AAPTLLPAAYLC-APTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESP 107
A L + +P+APP+ +A P P + P P+L L SP
Sbjct: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345
Query: 108 V--------PSAPGALAGGPTQAAP 124
P AP ALA P QA P
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPP 370
Score = 35.4 bits (80), Expect = 0.030
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 5/102 (4%)
Query: 41 EPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLA 100
E G AA+P L A + A + PA A G+ PG P P P ++
Sbjct: 611 EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA--PGAPLPWPPATGPGSADGLCTIY 668
Query: 101 EQHLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLR 142
E APGAL GP +PG G + GA R
Sbjct: 669 ETEGPESATPAPGALDPGP---SPGTSGGKAAAGAGAGASSR 707
Score = 33.5 bits (75), Expect = 0.12
Identities = 35/103 (33%), Positives = 40/103 (38%), Gaps = 10/103 (9%)
Query: 22 PRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGP 81
P P + PSA P LAA P P P APPA+ A P P
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP------PQAPPAL-ATPPLQALPSPP 496
Query: 82 RSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAP 124
S P G P P SL ++ L +P P AP LA Q P
Sbjct: 497 ASFP-GQAPFSPSASLPMSP--LATPPPQAPPVLAAPLLQVPP 536
Score = 33.1 bits (74), Expect = 0.15
Identities = 28/106 (26%), Positives = 37/106 (34%), Gaps = 2/106 (1%)
Query: 32 PSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPD 91
PS + P +P AP L L AP +PP P P P P
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429
Query: 92 GPQPSLSLAEQHLESPVPSAP--GALAGGPTQAAPGVRGEEEQWAR 135
PSL+ + P++P A P QA P + Q A+
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475
Score = 29.3 bits (64), Expect = 2.2
Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 17/104 (16%)
Query: 26 PLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRP 85
PL PSA P L P+ P P+ A T+ + T S P P S
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ---ATTSLGSPTLQATHSFLPSPPLSPL 350
Query: 86 RGPRPDGPQPSLSLAEQH-------------LESPVPSAPGALA 116
P P P P+L+L L +P P AP ALA
Sbjct: 351 ATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393
Score = 27.3 bits (59), Expect = 8.3
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 15/135 (11%)
Query: 7 EGSSPEPVE--GLARDGPRPFPLGRLVPSAVSCGLCEPGLAA-APAAPTLLPAAY--LCA 61
+ +SP PV G A RP PLG+ + G A AP L A
Sbjct: 98 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157
Query: 62 PTAPPAVTAALGGSRWPG--------GPRSRPRGPRPDGPQPSLSLAEQH-LESPVPSAP 112
PT A SR G P +RPR P +GP+ S+S A +H P P+A
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR-PPTEGPRKSVSSASEHSTTEPSPAAR 216
Query: 113 GALAGGPTQAAPGVR 127
+ G P R
Sbjct: 217 RRPSAGGGLQRPASR 231
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 38.5 bits (88), Expect = 0.004
Identities = 46/132 (34%), Positives = 49/132 (37%), Gaps = 22/132 (16%)
Query: 7 EGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAY----LCAP 62
EGSS V G P P G + P P A PA P LP L P
Sbjct: 812 EGSSMLTVPG------PPGPPGAMGPPG-------PPGAPGPAGPAGLPGHQEVLNLQGP 858
Query: 63 TAPPAVTAALGGS-RWPGGPRSRPRG--PRPDGPQPS-LSLAEQHLESPVPSAPGALAGG 118
PP G S P GPR P P P GP S LS +E L P P PG
Sbjct: 859 PGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGP-PGPPGPPGPK 917
Query: 119 PTQAAPGVRGEE 130
Q PG RG +
Sbjct: 918 GDQGPPGPRGHQ 929
Score = 27.3 bits (59), Expect = 8.3
Identities = 27/97 (27%), Positives = 30/97 (30%), Gaps = 26/97 (26%)
Query: 41 EPGLAAAPAAPTLLPAAYLCAPTAPPAVTAALG--------GSRWPGGPRSRPRGPRPDG 92
EPG+ P A A P P G G R P GP P P G
Sbjct: 723 EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTG 782
Query: 93 PQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGVRGE 129
PQ P L G P PG++GE
Sbjct: 783 PQ----------------GPQGLPGTP--GRPGIKGE 801
>gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens]
Length = 237
Score = 37.7 bits (86), Expect = 0.006
Identities = 47/162 (29%), Positives = 61/162 (37%), Gaps = 32/162 (19%)
Query: 11 PEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPT-APPAVT 69
PE GL+ P +P L A+ + E L +AP +P AP PP V
Sbjct: 28 PEAPLGLSAQ-PALWPT--LAALALLSSVAEASLGSAPRSP---------APREGPPPVL 75
Query: 70 AALGG-------SRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQA 122
A+ G +RW G RP P+P P P P P+ P AL G A
Sbjct: 76 ASPAGHLPGGRTARWCSGRARRPP-PQPSRPAP-----------PPPAPPSALPRGGRAA 123
Query: 123 APGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHR 164
G G + A G +LR + A R +E R R
Sbjct: 124 RAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFR 165
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 37.7 bits (86), Expect = 0.006
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 11/91 (12%)
Query: 47 APAAPTLLPAAYLCAPTAPPA-VTAALGGSRWPGGPRSRPRG--------PRPDGPQPSL 97
AP P L AA + A PP + + G+R PG +++ G P G ++
Sbjct: 503 APIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTV 562
Query: 98 SLAEQHLESPVPS--APGALAGGPTQAAPGV 126
+ HL S PS APGAL P APG+
Sbjct: 563 QSGQAHLASSPPSSQAPGALQECPPTLAPGM 593
>gi|23238226 CDC42 effector protein 1 [Homo sapiens]
Length = 391
Score = 37.7 bits (86), Expect = 0.006
Identities = 35/97 (36%), Positives = 43/97 (44%), Gaps = 10/97 (10%)
Query: 30 LVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTA--------PPAVTA-ALGGSRWPGG 80
L PS +S L L APAA T PAA APTA PPA TA + P
Sbjct: 202 LGPSLLSELLGVMSLPEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSA 261
Query: 81 PRSRPRGPRPDGPQPSLSLAEQ-HLESPVPSAPGALA 116
P + P GP + P P+ S H + V + G +A
Sbjct: 262 PAATPTGPAANPPAPAASSTPHGHCPNGVTAGLGPVA 298
Score = 33.9 bits (76), Expect = 0.088
Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 7/76 (9%)
Query: 42 PGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAE 101
P A P AP P+A PT P A A S S P G P+G L
Sbjct: 246 PATTANPPAPAANPSAPAATPTGPAANPPAPAAS-------STPHGHCPNGVTAGLGPVA 298
Query: 102 QHLESPVPSAPGALAG 117
+ SPV P AG
Sbjct: 299 EVKSSPVGGGPRGPAG 314
>gi|208431824 forkhead box I3 [Homo sapiens]
Length = 420
Score = 37.7 bits (86), Expect = 0.006
Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 9/93 (9%)
Query: 43 GLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRP------RGPRPDG-PQP 95
G+ + P P PAA AP APPA A G + + P + GP G P
Sbjct: 10 GVYSQPGLPP--PAATAAAPGAPPAARAPYGLADYAAPPAAAANPYLWLNGPGVGGPPSA 67
Query: 96 SLSLAEQHLESPVPSAPGALAGGPTQAAPGVRG 128
+ + A +L +P P P A GP P G
Sbjct: 68 AAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAG 100
Score = 34.3 bits (77), Expect = 0.068
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 15/95 (15%)
Query: 42 PGLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAE 101
PG+ P+A AAYL AP PP AA GP +P P G + ++
Sbjct: 59 PGVGGPPSAAAAAAAAYLGAPPPPPPPGAA-------AGPFLQP--PPAAG---TFGCSQ 106
Query: 102 QHLESPVPSAPGALAGGPTQAAPGVRGEEEQWARE 136
+ P P+AP + A A PG G +RE
Sbjct: 107 RPFAQPAPAAPASPA---APAGPGELGWLSMASRE 138
>gi|197100900 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 37.7 bits (86), Expect = 0.006
Identities = 35/96 (36%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 41 EPGLAAAPAAPTLLPAAYLCAPT-APPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSL 99
E GLA P T P L AP +PP A GG + P G R+ P P P SL
Sbjct: 274 ERGLAP-PKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSL 332
Query: 100 AE---QHLESP-------VPSAPGALAGGPTQAAPG 125
AE L+ P P P A A T A PG
Sbjct: 333 AEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPG 368
>gi|39930475 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 37.7 bits (86), Expect = 0.006
Identities = 35/96 (36%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 41 EPGLAAAPAAPTLLPAAYLCAPT-APPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSL 99
E GLA P T P L AP +PP A GG + P G R+ P P P SL
Sbjct: 274 ERGLAP-PKPVTSSPLTGLEAPLLSPPPEAAPRGGRKTPQGSRTSPGAPPPASKPKLWSL 332
Query: 100 AE---QHLESP-------VPSAPGALAGGPTQAAPG 125
AE L+ P P P A A T A PG
Sbjct: 333 AEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPG 368
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 37.7 bits (86), Expect = 0.006
Identities = 35/109 (32%), Positives = 42/109 (38%), Gaps = 15/109 (13%)
Query: 2 ARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCA 61
A A Q P PV P P G P S + AAAP
Sbjct: 665 AMADQSAGQPSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAP------------- 711
Query: 62 PTAPPAV-TAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAE-QHLESPV 108
P A P+V T+ L SR PR RP P P P +LS + Q E+P+
Sbjct: 712 PLASPSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPM 760
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 37.4 bits (85), Expect = 0.008
Identities = 47/166 (28%), Positives = 61/166 (36%), Gaps = 34/166 (20%)
Query: 9 SSPEPVEGLA-----RDGPRPFPLGRLVPSAVSCGL--CEPGLAAAPAAPTLLPAAYLCA 61
++P+PV+ +A GP P P P A P L A+PA P A L
Sbjct: 1279 TAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHV 1338
Query: 62 PTAPP-AVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPT 120
P PP A AA + P P P+G P S A Q LE LA
Sbjct: 1339 PAKPPRAAAAAAAAAAAPPAP--------PEGASPGDS-ARQKLE----ETSACLAAALQ 1385
Query: 121 QAAPGVRGEEEQWAR-------------EIGAQLRRMADDLNAQYE 153
+R E+ Q R +IG+ +AD L+A E
Sbjct: 1386 AVEEKIRQEDAQGPRDSAAEKSTGSILDDIGSMFDDLADQLDAMLE 1431
Score = 35.4 bits (80), Expect = 0.030
Identities = 54/181 (29%), Positives = 67/181 (37%), Gaps = 29/181 (16%)
Query: 10 SPEPVEGLARDGPR----PFPLGRLVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPTAP 65
SP+PV L + P+ P P + VP G P + A P + PTAP
Sbjct: 1227 SPKPV--LTQPVPKLQGSPTPTSKKVPLP---GPGSPEVKRAHGTPPPVSPKPPPPPTAP 1281
Query: 66 PAVTAALG---GSRWPGGPRSRPRGP-----RPDGPQPSLSLAEQHLESP------VPSA 111
V A G GS P S R P +P G PSL + SP VP+
Sbjct: 1282 KPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAK 1341
Query: 112 P--GALAGGPTQAAPGVRGEEEQWAREIGAQLRR----MADDLNAQYERRRQEEQQRHRP 165
P A A AAP E +L +A L A E+ RQE+ Q R
Sbjct: 1342 PPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRD 1401
Query: 166 S 166
S
Sbjct: 1402 S 1402
>gi|239754940 PREDICTED: hypothetical protein [Homo sapiens]
Length = 159
Score = 37.4 bits (85), Expect = 0.008
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 17/85 (20%)
Query: 43 GLAAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQ 102
G A+P P L P P AP PG +RP P P P P + A+
Sbjct: 90 GDIASPLPPALQPRGAPAVPAAPS-----------PGPLPARPSSPPPSPPSPPVPTAQS 138
Query: 103 HLESPVPSAPGALAGGPTQAAPGVR 127
L +P P GP AP +R
Sbjct: 139 SLPAPWPPQ------GPRSPAPSLR 157
>gi|239753673 PREDICTED: hypothetical protein [Homo sapiens]
Length = 380
Score = 37.4 bits (85), Expect = 0.008
Identities = 40/130 (30%), Positives = 52/130 (40%), Gaps = 25/130 (19%)
Query: 18 ARDGPRPFPLGRLVPSAVSCGLCE-PGLAAAPAAPTLLPAAYLCAPTAPPA----VTAAL 72
+R PR + L L +S + L + P P + C A V A
Sbjct: 4 SRPAPRQWVLRPLPSPVLSAAMVSRASLQSKPGIPPIPVRRGHCCSRVRVADGQHVDPAG 63
Query: 73 GGSRWPGG-----------PRSRPR----GPRPDGPQPS--LSLAEQHLESPVPSAPGAL 115
G RW GG PRS PR GP GPQ L L+E+H+ + +P A G L
Sbjct: 64 AGRRWRGGLRGGFAPAAARPRSAPRRRILGPGGRGPQAEVPLVLSERHVPAGIPGARGRL 123
Query: 116 A---GGPTQA 122
A GG +A
Sbjct: 124 APARGGAARA 133
Score = 28.9 bits (63), Expect = 2.8
Identities = 28/82 (34%), Positives = 32/82 (39%), Gaps = 6/82 (7%)
Query: 50 APTLLPAAYLCAPTAPPAVTAALGGSRWP--GGPRSRPRGPRPDGPQPSLSLAEQHLESP 107
A L+PA A A A G+R P G RSRPR RP P P S
Sbjct: 154 AVQLVPAPRQAAQAADTGPRHASPGARRPAPGARRSRPRLLRPASPPPR---PAPRRRST 210
Query: 108 VPSAPGALAG-GPTQAAPGVRG 128
P G G G T+ P + G
Sbjct: 211 APRHEGGRPGRGRTRRQPHLAG 232
>gi|239748304 PREDICTED: hypothetical protein XP_002346608 [Homo
sapiens]
Length = 285
Score = 37.4 bits (85), Expect = 0.008
Identities = 40/130 (30%), Positives = 52/130 (40%), Gaps = 25/130 (19%)
Query: 18 ARDGPRPFPLGRLVPSAVSCGLCE-PGLAAAPAAPTLLPAAYLCAPTAPPA----VTAAL 72
+R PR + L L +S + L + P P + C A V A
Sbjct: 4 SRPAPRQWVLRPLPSPVLSAAMVSRASLQSKPGIPPIPVRRGHCCSRVRVADGQHVDPAG 63
Query: 73 GGSRWPGG-----------PRSRPR----GPRPDGPQPS--LSLAEQHLESPVPSAPGAL 115
G RW GG PRS PR GP GPQ L L+E+H+ + +P A G L
Sbjct: 64 AGRRWRGGLRGGFAPAAARPRSAPRRRILGPGGRGPQAEVPLVLSERHVPAGIPGARGRL 123
Query: 116 A---GGPTQA 122
A GG +A
Sbjct: 124 APARGGAARA 133
>gi|209954781 neurotrophic factor artemin isoform 1 precursor [Homo
sapiens]
Length = 220
Score = 37.4 bits (85), Expect = 0.008
Identities = 41/143 (28%), Positives = 53/143 (37%), Gaps = 29/143 (20%)
Query: 30 LVPSAVSCGLCEPGLAAAPAAPTLLPAAYLCAPT-APPAVTAALGG-------SRWPGGP 81
L A+ + E L +AP +P AP PP V A+ G +RW G
Sbjct: 27 LAALALLSSVAEASLGSAPRSP---------APREGPPPVLASPAGHLPGGRTARWCSGR 77
Query: 82 RSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQL 141
RP P+P P P P P+ P AL G A G G + A G +L
Sbjct: 78 ARRPP-PQPSRPAP-----------PPPAPPSALPRGGRAARAGGPGSRARAAGARGCRL 125
Query: 142 RRMADDLNAQYERRRQEEQQRHR 164
R + A R +E R R
Sbjct: 126 RSQLVPVRALGLGHRSDELVRFR 148
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,344,890
Number of Sequences: 37866
Number of extensions: 797756
Number of successful extensions: 5862
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 850
Number of HSP's that attempted gapping in prelim test: 4516
Number of HSP's gapped (non-prelim): 1995
length of query: 193
length of database: 18,247,518
effective HSP length: 97
effective length of query: 96
effective length of database: 14,574,516
effective search space: 1399153536
effective search space used: 1399153536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.