Guide to the Human Genome
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Search of human proteins with 15149472

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]
         (374 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]             754   0.0  
gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]              490   e-139
gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]    489   e-138
gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]             472   e-133
gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo sapi...   432   e-121
gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]                   64   2e-10
gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]                   64   2e-10
gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]                   64   2e-10
gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]                   64   2e-10
gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]                   64   2e-10
gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]                   64   2e-10
gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]                   64   2e-10
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho...    64   2e-10
gi|4505151 Meis homeobox 1 [Homo sapiens]                              64   3e-10
gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]                    61   1e-09
gi|219275578 SIX homeobox 2 [Homo sapiens]                             60   3e-09
gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]                   60   3e-09
gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo ...    59   5e-09
gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo ...    55   8e-08
gi|28178843 TG-interacting factor isoform a [Homo sapiens]             55   1e-07
gi|4507473 TG-interacting factor isoform c [Homo sapiens]              55   1e-07
gi|28178855 TG-interacting factor isoform d [Homo sapiens]             55   1e-07
gi|28178853 TG-interacting factor isoform d [Homo sapiens]             55   1e-07
gi|28178851 TG-interacting factor isoform d [Homo sapiens]             55   1e-07
gi|28178857 TG-interacting factor isoform d [Homo sapiens]             55   1e-07
gi|28178849 TG-interacting factor isoform c [Homo sapiens]             55   1e-07
gi|28178845 TG-interacting factor isoform b [Homo sapiens]             55   1e-07
gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]              55   1e-07
gi|7705555 iroquois homeobox 4 [Homo sapiens]                          52   7e-07
gi|5174681 SIX homeobox 1 [Homo sapiens]                               52   1e-06

>gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]
          Length = 374

 Score =  754 bits (1948), Expect = 0.0
 Identities = 374/374 (100%), Positives = 374/374 (100%)

Query: 1   MAAPPRPAPSPPAPRRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEI 60
           MAAPPRPAPSPPAPRRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEI
Sbjct: 1   MAAPPRPAPSPPAPRRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEI 60

Query: 61  KEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDN 120
           KEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDN
Sbjct: 61  KEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDN 120

Query: 121 SIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGA 180
           SIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGA
Sbjct: 121 SIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGA 180

Query: 181 IHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSE 240
           IHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSE
Sbjct: 181 IHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSE 240

Query: 241 EAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHA 300
           EAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHA
Sbjct: 241 EAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHA 300

Query: 301 SCLSTPSSGSSGPFPLPSAGDAFLTLRTLASLQPPPGGGCLQSQAQGSWQGATPQPATAS 360
           SCLSTPSSGSSGPFPLPSAGDAFLTLRTLASLQPPPGGGCLQSQAQGSWQGATPQPATAS
Sbjct: 301 SCLSTPSSGSSGPFPLPSAGDAFLTLRTLASLQPPPGGGCLQSQAQGSWQGATPQPATAS 360

Query: 361 PAGDPGSINSSTSN 374
           PAGDPGSINSSTSN
Sbjct: 361 PAGDPGSINSSTSN 374


>gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]
          Length = 430

 Score =  490 bits (1262), Expect = e-139
 Identities = 259/393 (65%), Positives = 294/393 (74%), Gaps = 34/393 (8%)

Query: 15  RRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRGIQDE 74
           R+ D  D+LQQIM ITDQSLDEAQARKHALNCHRMKPALF+VLCEIKEKTV+SIRG Q+E
Sbjct: 39  RKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEE 98

Query: 75  DPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDNSIEHSDYRAKLSQI 134
           +P D QL+RLDNMLLAEGV  PEK G G A A A  A  GG  +DNS+EHSDYRAKLSQI
Sbjct: 99  EPTDPQLMRLDNMLLAEGVAGPEKGG-GSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQI 157

Query: 135 RQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQMQLKQ 194
           RQIYH+ELEKYEQAC EFTTHV NLL+EQSR RP+SPKEIERMV  IH KFS+IQMQLKQ
Sbjct: 158 RQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQ 217

Query: 195 STCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTI 254
           STCEAVM LRSR LDARRKRRNF+KQATE+LNEYFYSHL+NPYPSEEAKEELA+K G+T+
Sbjct: 218 STCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITV 277

Query: 255 SQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLSTP-SSGSSGP 313
           SQVSNWFGNKRIRYKKN+GKFQEEA IY  KTAV  T V   G+ A+  STP S+GSS  
Sbjct: 278 SQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSS 337

Query: 314 FPLPSAGDAFLTLRTL--ASLQPPPGGGCLQSQ--------------------------- 344
           F + ++GD F+++++L   S Q    G  +QSQ                           
Sbjct: 338 FNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQ 397

Query: 345 ---AQGSWQGATPQPATASPAGDPGSINSSTSN 374
              A G WQ AT   +  SP   PGS++S TSN
Sbjct: 398 GISANGGWQDATTPSSVTSPTEGPGSVHSDTSN 430


>gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]
          Length = 434

 Score =  489 bits (1259), Expect = e-138
 Identities = 265/412 (64%), Positives = 297/412 (72%), Gaps = 40/412 (9%)

Query: 1   MAAPPRPAPSPPAP---RRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVL 57
           MA PP P     A    R+ D  D+L QIM ITDQSLDEAQA+KHALNCHRMKPALFSVL
Sbjct: 25  MALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVL 84

Query: 58  CEIKEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCP 117
           CEIKEKT +SIRG Q+EDPPD QL+RLDNMLLAEGV  PEK G G A A A  A  GG  
Sbjct: 85  CEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGG-GSAAAAAAAAASGGS- 142

Query: 118 NDNSIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERM 177
           +DNSIEHSDYRAKL+QIRQIYH+ELEKYEQAC EFTTHV NLL+EQSR RP+SPKEIERM
Sbjct: 143 SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERM 202

Query: 178 VGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPY 237
           VG IH KFS+IQMQLKQSTCEAVM LRSR LDARRKRRNFSKQATE+LNEYFYSHL+NPY
Sbjct: 203 VGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPY 262

Query: 238 PSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEV---G 294
           PSEEAKEELA+K  +T+SQVSNWFGNKRIRYKKN+GKFQEEA +Y  KTAV         
Sbjct: 263 PSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAA 322

Query: 295 VPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLA--SLQPPPGGGCLQSQ-------- 344
           V  N  +  +TP+SGSSG F LP++GD F+ +++L   S Q    G  +QSQ        
Sbjct: 323 VQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVI 382

Query: 345 ----------------------AQGSWQGATPQPATASPAGDPGSINSSTSN 374
                                 A G WQ AT   +  SP   PGS++S TSN
Sbjct: 383 NQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN 434


>gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
          Length = 430

 Score =  472 bits (1214), Expect = e-133
 Identities = 258/390 (66%), Positives = 287/390 (73%), Gaps = 30/390 (7%)

Query: 11  PPAPRRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRG 70
           P    + D  D+LQQIM ITDQSLDEAQA+KHALNCHRMKPALFSVLCEIKEKT +SIR 
Sbjct: 45  PGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRS 104

Query: 71  IQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDNSIEHSDYRAK 130
            Q+E+P D QL+RLDNMLLAEGV  PEK G   A A A  A+ GG   DNSIEHSDYR+K
Sbjct: 105 SQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSK 164

Query: 131 LSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQM 190
           L+QIR IYHSELEKYEQAC EFTTHV NLL+EQSR RPV+PKE+ERMV  IH KFSAIQM
Sbjct: 165 LAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQM 224

Query: 191 QLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKG 250
           QLKQSTCEAVM LRSR LDARRKRRNFSKQATEVLNEYFYSHL+NPYPSEEAKEELA+K 
Sbjct: 225 QLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKC 284

Query: 251 GLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLS-TP--S 307
           G+T+SQVSNWFGNKRIRYKKN+GKFQEEA IY  KTAV  T+    G H+   S TP  S
Sbjct: 285 GITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQ----GGHSRTSSPTPPSS 340

Query: 308 SGSSGPFPLPSAGDAFLTLRTL--------------ASLQPPP-----GGGCLQS----Q 344
           +GS G F L  +GD FL +  L               S+ P       GGG + S    +
Sbjct: 341 AGSGGSFNLSGSGDMFLGMPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMR 400

Query: 345 AQGSWQGATPQPATASPAGDPGSINSSTSN 374
           A GSWQ A    +  SP   PGS++S TSN
Sbjct: 401 ANGSWQEAVTPSSVTSPTEGPGSVHSDTSN 430


>gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo
           sapiens]
          Length = 359

 Score =  432 bits (1111), Expect = e-121
 Identities = 233/361 (64%), Positives = 262/361 (72%), Gaps = 37/361 (10%)

Query: 49  MKPALFSVLCEIKEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARA 108
           MKPALFSVLCEIKEKT +SIRG Q+EDPPD QL+RLDNMLLAEGV  PEK G G A A A
Sbjct: 1   MKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGG-GSAAAAA 59

Query: 109 GTATPGGCPNDNSIEHSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRP 168
             A  GG  +DNSIEHSDYRAKL+QIRQIYH+ELEKYEQAC EFTTHV NLL+EQSR RP
Sbjct: 60  AAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRP 118

Query: 169 VSPKEIERMVGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEY 228
           +SPKEIERMVG IH KFS+IQMQLKQSTCEAVM LRSR LDARRKRRNFSKQATE+LNEY
Sbjct: 119 ISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEY 178

Query: 229 FYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAV 288
           FYSHL+NPYPSEEAKEELA+K  +T+SQVSNWFGNKRIRYKKN+GKFQEEA +Y  KTAV
Sbjct: 179 FYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAV 238

Query: 289 DTTEV---GVPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLA--SLQPPPGGGCLQS 343
                    V  N  +  +TP+SGSSG F LP++GD F+ +++L   S Q    G  +QS
Sbjct: 239 TAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQS 298

Query: 344 Q------------------------------AQGSWQGATPQPATASPAGDPGSINSSTS 373
           Q                              A G WQ AT   +  SP   PGS++S TS
Sbjct: 299 QVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTS 358

Query: 374 N 374
           N
Sbjct: 359 N 359


>gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]
          Length = 306

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/62 (48%), Positives = 42/62 (67%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  +
Sbjct: 189 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQ 248

Query: 271 NM 272
            M
Sbjct: 249 PM 250


>gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]
          Length = 388

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/62 (48%), Positives = 42/62 (67%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  +
Sbjct: 264 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQ 323

Query: 271 NM 272
            M
Sbjct: 324 PM 325


>gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]
          Length = 401

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/62 (48%), Positives = 42/62 (67%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  +
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQ 336

Query: 271 NM 272
            M
Sbjct: 337 PM 338


>gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]
          Length = 470

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/62 (48%), Positives = 42/62 (67%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  +
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQ 336

Query: 271 NM 272
            M
Sbjct: 337 PM 338


>gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]
          Length = 477

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/62 (48%), Positives = 42/62 (67%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  +
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQ 336

Query: 271 NM 272
            M
Sbjct: 337 PM 338


>gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]
          Length = 394

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/62 (48%), Positives = 42/62 (67%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  +
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQ 336

Query: 271 NM 272
            M
Sbjct: 337 PM 338


>gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]
          Length = 381

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/62 (48%), Positives = 42/62 (67%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  +
Sbjct: 264 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQ 323

Query: 271 NM 272
            M
Sbjct: 324 PM 325


>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
           homolog 3 isoform 2 [Homo sapiens]
          Length = 358

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 30/61 (49%), Positives = 42/61 (68%)

Query: 212 RKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKN 271
           +KR  F K AT ++  + + HL++PYPSEE K++LA+  GLTI QV+NWF N R R  + 
Sbjct: 247 KKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQP 306

Query: 272 M 272
           M
Sbjct: 307 M 307


>gi|4505151 Meis homeobox 1 [Homo sapiens]
          Length = 390

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 30/61 (49%), Positives = 41/61 (67%)

Query: 212 RKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKN 271
           +KR  F K AT ++  + + HL +PYPSEE K++LA+  GLTI QV+NWF N R R  + 
Sbjct: 274 KKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQP 333

Query: 272 M 272
           M
Sbjct: 334 M 334


>gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]
          Length = 436

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 54/197 (27%), Positives = 86/197 (43%), Gaps = 16/197 (8%)

Query: 179 GAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYP 238
           G I  + S +Q+QL Q     +  L      ++ KR    K AT V+  + + H+ +PYP
Sbjct: 232 GTIRIQNSQLQLQLNQD----LSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYP 287

Query: 239 SEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVG--VP 296
           +E+ K+++A +  LT+ QV+NWF N R R  + M       T  T K       V    P
Sbjct: 288 TEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWP 347

Query: 297 GNHASCLSTPSSGSSGPFPLPSAGDAFLTLRT-----LASLQPPPGGGCLQSQAQGSWQG 351
            + AS ++ P      P  L  +  A +T+ T     + SLQ     G   +  Q    G
Sbjct: 348 DSIASGVAQPP-----PSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAG 402

Query: 352 ATPQPATASPAGDPGSI 368
            +   +  S   D G++
Sbjct: 403 QSEDESVDSTEEDAGAL 419


>gi|219275578 SIX homeobox 2 [Homo sapiens]
          Length = 291

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 48/154 (31%), Positives = 63/154 (40%), Gaps = 22/154 (14%)

Query: 217 FSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQ 276
           F +++  VL E+ Y+H  NPYPS   K ELA   GLT +QVSNWF N+R R +    K +
Sbjct: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187

Query: 277 E-----EATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLAS 331
           E      +  +        + +G   +  +   TP   SS P  L S             
Sbjct: 188 ENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLS------------- 234

Query: 332 LQPPPGGGCLQSQAQGSWQGATPQPATASPAGDP 365
             PPPG   L S        A P P       DP
Sbjct: 235 -PPPPGLPSLHSLGHPPGPSAVPVPVPGGGGADP 267


>gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
          Length = 472

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 30/86 (34%), Positives = 48/86 (55%)

Query: 187 AIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEEL 246
           AIQ+Q  Q   +    L +    ++ KR    K AT ++  + + HL +PYP+E+ K ++
Sbjct: 265 AIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQI 324

Query: 247 ARKGGLTISQVSNWFGNKRIRYKKNM 272
           A +  LT+ QV+NWF N R R  + M
Sbjct: 325 AAQTNLTLLQVNNWFINARRRILQPM 350


>gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo
           sapiens]
          Length = 241

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 33/103 (32%), Positives = 52/103 (50%), Gaps = 2/103 (1%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++++ N   ++ ++L ++ Y H    YPSEE K+ L+ K  L++ Q+SNWF N R R   
Sbjct: 51  KKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILP 110

Query: 271 NMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGP 313
           +M + +    I   KT  D     +    AS      SG SGP
Sbjct: 111 DMLQQRRNDPIIGHKTGKDAHATHLQSTEASV--PAKSGPSGP 151


>gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo
           sapiens]
          Length = 185

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 7/102 (6%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           ++++ N   ++ ++L ++ Y H    YPSEE K+ L+ K  L++ ++SNWF N R R   
Sbjct: 51  KKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLRISNWFINARRRILP 110

Query: 271 NMGKFQEEATIYTGKTAVD-------TTEVGVPGNHASCLST 305
           +M + +    I   KT  D       +TE  VP      + T
Sbjct: 111 DMLQQRRNDPIIGHKTGKDAHATHLQSTEASVPAKSGPVVQT 152


>gi|28178843 TG-interacting factor isoform a [Homo sapiens]
          Length = 401

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 165 RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 224

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 225 DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 279


>gi|4507473 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 36  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 95

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 96  DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 150


>gi|28178855 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 75

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 76  DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 130


>gi|28178853 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 75

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 76  DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 130


>gi|28178851 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 75

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 76  DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 130


>gi|28178857 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 75

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 76  DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 130


>gi|28178849 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 36  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 95

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 96  DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 150


>gi|28178845 TG-interacting factor isoform b [Homo sapiens]
          Length = 286

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 10/115 (8%)

Query: 211 RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 270
           RR+R N  K++ ++L ++ Y H  N YPSE+ K  L+++  L+  QV NWF N R R   
Sbjct: 50  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLP 109

Query: 271 NM----GKFQEEATIYTGKTAVDTTE-----VGVPGNHASCLSTP-SSGSSGPFP 315
           +M    GK   + TI      +  T      +G+     +   TP  S ++GP P
Sbjct: 110 DMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNP 164


>gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]
          Length = 237

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 47/165 (28%), Positives = 65/165 (39%), Gaps = 34/165 (20%)

Query: 207 LLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRI 266
           L   R++R N  K++ ++L ++ Y H  N YPSE+ K  L+ +  L++ Q+ NWF N R 
Sbjct: 15  LAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARR 74

Query: 267 RYKKNM-----------------GKFQEEATIYTGKTAVDTTEVGVPGN--HASCLSTPS 307
           R   +M                 GK  + A       +V    V  P N    S  S P 
Sbjct: 75  RLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLAVSVPAPTNVLSLSVCSMPL 134

Query: 308 SGSSG--------------PFPLPSAGDAFLTLRTLASLQPPPGG 338
               G              P PL + G   LTL T A    P GG
Sbjct: 135 HSGQGEKPAAPFPRGELESPKPLVTPGST-LTLLTRAEAGSPTGG 178


>gi|7705555 iroquois homeobox 4 [Homo sapiens]
          Length = 519

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 24/63 (38%), Positives = 37/63 (58%)

Query: 208 LDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIR 267
           +D+  +R+N +++ T  L  +   H  NPYP++  K  LA    +T++QVS WF N R R
Sbjct: 140 MDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 199

Query: 268 YKK 270
            KK
Sbjct: 200 LKK 202


>gi|5174681 SIX homeobox 1 [Homo sapiens]
          Length = 284

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 29/61 (47%), Positives = 38/61 (62%), Gaps = 3/61 (4%)

Query: 217 FSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQ 276
           F +++  VL E+ Y+H  NPYPS   K ELA   GLT +QVSNWF N+R R +    K +
Sbjct: 131 FKEKSRGVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187

Query: 277 E 277
           E
Sbjct: 188 E 188


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,920,947
Number of Sequences: 37866
Number of extensions: 883984
Number of successful extensions: 5211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 4729
Number of HSP's gapped (non-prelim): 621
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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