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Search of human proteins with 15147248
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo
sapiens]
(307 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo sap... 613 e-176
gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo sap... 603 e-173
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 64 1e-10
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 64 1e-10
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 64 1e-10
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 64 1e-10
gi|148746195 trichohyalin [Homo sapiens] 62 8e-10
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 59 7e-09
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 57 3e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 8e-08
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 55 8e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 2e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 54 2e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 54 2e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 53 3e-07
gi|81295809 pericentrin [Homo sapiens] 53 4e-07
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 52 7e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 51 1e-06
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 51 1e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 3e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 50 3e-06
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 49 4e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 6e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 49 6e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 7e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 49 7e-06
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 49 7e-06
gi|71061468 centromere protein E [Homo sapiens] 48 1e-05
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 48 1e-05
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 48 1e-05
>gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo
sapiens]
Length = 307
Score = 613 bits (1581), Expect = e-176
Identities = 307/307 (100%), Positives = 307/307 (100%)
Query: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG
Sbjct: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR
Sbjct: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE
Sbjct: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKM 240
AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKM
Sbjct: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKM 240
Query: 241 KDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMN 300
KDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMN
Sbjct: 241 KDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMN 300
Query: 301 SGNSWGI 307
SGNSWGI
Sbjct: 301 SGNSWGI 307
>gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo
sapiens]
Length = 410
Score = 603 bits (1555), Expect = e-173
Identities = 306/317 (96%), Positives = 306/317 (96%), Gaps = 11/317 (3%)
Query: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG
Sbjct: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR
Sbjct: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE
Sbjct: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSST-----------WARSWAYRDSL 229
AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSST WARSWAYRDSL
Sbjct: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL 240
Query: 230 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 289
KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG
Sbjct: 241 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 300
Query: 290 LEQSGGCWNMNSGNSWG 306
LEQSGGCWNMNSGNSWG
Sbjct: 301 LEQSGGCWNMNSGNSWG 317
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/203 (26%), Positives = 103/203 (50%), Gaps = 27/203 (13%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 788 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 839
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 840 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 899
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWAR-----------SWAYRDSLKAEENRKLQKMKD 242
L +L + + Q + P SSTW + + + + K EE R+ Q ++
Sbjct: 900 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 957
Query: 243 EQHQKSELLELKRQQQEQERAKI 265
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 958 QRRQQRELMKALQQQQQQQQQKL 980
Score = 54.7 bits (130), Expect = 1e-07
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 776 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 835
Query: 197 LNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQ 256
E +++ WAR ++ + E +L+ ++ + E E KR+
Sbjct: 836 KQEE--------------EAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRK 879
Query: 257 QQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWG 306
+ E +R K + ++ A L RLQ + Q L Q + S ++WG
Sbjct: 880 ELEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQ----MKLPSSSTWG 924
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/203 (26%), Positives = 103/203 (50%), Gaps = 27/203 (13%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 815 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 866
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 867 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 926
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWAR-----------SWAYRDSLKAEENRKLQKMKD 242
L +L + + Q + P SSTW + + + + K EE R+ Q ++
Sbjct: 927 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 984
Query: 243 EQHQKSELLELKRQQQEQERAKI 265
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 985 QRRQQRELMKALQQQQQQQQQKL 1007
Score = 54.7 bits (130), Expect = 1e-07
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 803 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 862
Query: 197 LNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQ 256
E +++ WAR ++ + E +L+ ++ + E E KR+
Sbjct: 863 KQEE--------------EAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRK 906
Query: 257 QQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWG 306
+ E +R K + ++ A L RLQ + Q L Q + S ++WG
Sbjct: 907 ELEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQ----MKLPSSSTWG 951
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/203 (26%), Positives = 103/203 (50%), Gaps = 27/203 (13%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 794 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 845
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 905
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWAR-----------SWAYRDSLKAEENRKLQKMKD 242
L +L + + Q + P SSTW + + + + K EE R+ Q ++
Sbjct: 906 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 963
Query: 243 EQHQKSELLELKRQQQEQERAKI 265
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 964 QRRQQRELMKALQQQQQQQQQKL 986
Score = 54.7 bits (130), Expect = 1e-07
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Query: 197 LNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQ 256
E +++ WAR ++ + E +L+ ++ + E E KR+
Sbjct: 842 KQEE--------------EAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Query: 257 QQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWG 306
+ E +R K + ++ A L RLQ + Q L Q + S ++WG
Sbjct: 886 ELEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQ----MKLPSSSTWG 930
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/203 (26%), Positives = 103/203 (50%), Gaps = 27/203 (13%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 794 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 845
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 905
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWAR-----------SWAYRDSLKAEENRKLQKMKD 242
L +L + + Q + P SSTW + + + + K EE R+ Q ++
Sbjct: 906 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 963
Query: 243 EQHQKSELLELKRQQQEQERAKI 265
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 964 QRRQQRELMKALQQQQQQQQQKL 986
Score = 54.7 bits (130), Expect = 1e-07
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Query: 197 LNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQ 256
E +++ WAR ++ + E +L+ ++ + E E KR+
Sbjct: 842 KQEE--------------EAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Query: 257 QQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWG 306
+ E +R K + ++ A L RLQ + Q L Q + S ++WG
Sbjct: 886 ELEVQRQKELMRQRQQQQEA-LRRLQQQQQQQQLAQ----MKLPSSSTWG 930
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 61.6 bits (148), Expect = 8e-10
Identities = 52/204 (25%), Positives = 100/204 (49%), Gaps = 17/204 (8%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL---QLMQSKYK 133
R E Q EQ+L ++ + + R K R +SE ++R++Q+ QL++ + +
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEE 555
Query: 134 QKLKREE-SVRIKKEAEEA--ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKT 190
++L++E R+K+E EE +L K + +R++ K E+++RL++ L+RE +Q +
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 191 AEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRD---------SLKAEENRKLQKMK 241
E +L E P+ Q + + + R+ + EE R Q++K
Sbjct: 616 RE--QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK 673
Query: 242 DEQHQKSELLELKRQQQEQERAKI 265
E ++ EL ++QEQ R +I
Sbjct: 674 REHEEERREQELAEEEQEQARERI 697
Score = 60.8 bits (146), Expect = 1e-09
Identities = 55/218 (25%), Positives = 101/218 (46%), Gaps = 16/218 (7%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135
RR E R +E L + Q R + ++L + E + R+++QL+ Q +++
Sbjct: 1685 RRQERDRKFREEEQQLRR---QERERKFLQEEQQLRRQELERKFREEEQLR--QETEQEQ 1739
Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLS 195
L+R+E R +K EE +L+ + Q+ + + + K R +E LR+E RE QQ ++ E
Sbjct: 1740 LRRQE--RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE--REEQQLRSQESDR 1795
Query: 196 KLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELL---- 251
K E R + PQ W E+ ++L++ +D Q++ E
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 252 ELKRQQQE---QERAKIHQTEHRRVNNAFLDRLQGKSQ 286
+ +R++QE +E K Q R++ + R Q + Q
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 56.6 bits (135), Expect = 3e-08
Identities = 57/256 (22%), Positives = 123/256 (48%), Gaps = 27/256 (10%)
Query: 26 DPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAE 85
+P RQ E P + +R+ K +E + G+ ++ + + + QR E
Sbjct: 123 EPRDRQLEEEPGQRRRQ------KRQEQERELAEGEEQSEKQERL-----EQRDRQRRDE 171
Query: 86 QELANLEKWKEQNRAKPVHLVPRRLGGSQSET-----EVRQKQQLQLMQS--KYKQKLKR 138
+ ++W+E+ + + G ++E ++R+++ L+L + + KQ+ +R
Sbjct: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231
Query: 139 EESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198
E R+ +E EE E +K + + R++ KL+E++ ++ RE E +Q + E +L
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ---RELQEEEEQLRKLE-RQELR 287
Query: 199 TESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQ 258
E + Q + Q + R+ + EE R+ Q+ +++Q ++ E +L+R+Q+
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERRE--QQEERREQQERREQQEERREQ-QLRREQE 344
Query: 259 E--QERAKIHQTEHRR 272
E +++ + Q E RR
Sbjct: 345 ERREQQLRREQEEERR 360
Score = 56.6 bits (135), Expect = 3e-08
Identities = 56/221 (25%), Positives = 108/221 (48%), Gaps = 24/221 (10%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL-MQSKYKQ 134
R +++R E+E + +EQ + L RR + E ++R++QQL+ Q + +Q
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194
+L+RE+ +R ++E E E QK + +RE+ K E+++R R E H+Q + + L
Sbjct: 418 QLRREQQLRREQEEERHE-QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 195 SKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELK 254
+ E + W + + + ++ R+ Q+++ EQ ++ E LK
Sbjct: 477 KRDQEEE-------------RRERWLK--LEEEERREQQERREQQLRREQEERRE-QRLK 520
Query: 255 RQQQE---QERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQ 292
RQ++E Q+R + Q + RR ++L + + LEQ
Sbjct: 521 RQEEEERLQQRLRSEQ-QLRREQEERREQLLKREEEKRLEQ 560
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/196 (20%), Positives = 97/196 (49%), Gaps = 6/196 (3%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL--QLMQSKYK 133
R+ +++R E+E E+W + + RR + E E R++Q+L Q + + +
Sbjct: 472 RKQQLKRDQEEE--RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEF 193
Q+L+ E+ +R ++E +L K + +R + + E++ + ++ RR+ + ++ + +
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLEL 253
L + E ++ + V + R+ + EE R+ Q +K E+ ++ +L
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKRE--EPEEERRQQLLKSEEQEERRQQQL 647
Query: 254 KRQQQEQERAKIHQTE 269
+R+QQE+ ++ + E
Sbjct: 648 RREQQERREQRLKREE 663
Score = 56.2 bits (134), Expect = 4e-08
Identities = 63/259 (24%), Positives = 112/259 (43%), Gaps = 21/259 (8%)
Query: 25 QDPSGRQGELSPVEDQ---REGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQ 81
Q G + E P E+Q RE LE KG E +R+ + R+ E
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKG-REEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141
E+E E+ + Q + R+L + E ++++Q Q Q+L+RE+
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ-------QRLRREQQ 305
Query: 142 VRIKKEAEEAELQKMKAIQREKSNKLEEK-----KRLQENLRREAFREHQQYKTAEFLSK 196
+R K+E E E Q+ + Q+E+ + EE+ +R QE R + R Q+ + E +
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 197 LNTESPDRS---ACQSAVCGPQSSTWARSWAYRDSLKAEEN-RKLQKMKDEQHQKSELLE 252
E R + + Q + L+ E+ R+ Q+++ EQ + E +
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQ 424
Query: 253 LKRQQQEQERAKIHQTEHR 271
L+R+Q+E+ + H+ E R
Sbjct: 425 LRREQEEERHEQKHEQERR 443
Score = 55.8 bits (133), Expect = 5e-08
Identities = 52/204 (25%), Positives = 98/204 (48%), Gaps = 36/204 (17%)
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
+RR + Y A R E Q + E+E + +E+ R + + E + R
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ------------EQERQYR 931
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKL---EEKKRLQENL 177
+++QLQ + +++L REE + +++ E + +K K +Q+++ L EK+R QE
Sbjct: 932 EEEQLQ----QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE-- 985
Query: 178 RREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKL 237
R + +RE ++ + E +L E ++ Q W R + +D L+ EE + L
Sbjct: 986 REKKYREEEELQQEE--EQLLREEREKRRRQE---------WERQYRKKDELQQEEEQLL 1034
Query: 238 QKMKDEQHQKSELLELKRQQQEQE 261
+ E+ +K L E +RQ +E+E
Sbjct: 1035 R----EEREKRRLQERERQYREEE 1054
Score = 53.9 bits (128), Expect = 2e-07
Identities = 51/225 (22%), Positives = 108/225 (48%), Gaps = 29/225 (12%)
Query: 76 RRNEIQRIAEQELAN-LEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL-MQSKYK 133
RR + + EQ+L E+ +EQ + R + + E R++QQL+ Q + +
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTA 191
Q+L+RE+ +R E +L++ + ++RE+ + E++ R ++ LRR E R Q+++
Sbjct: 387 QQLRREQQLR-----REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 192 EFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYR--DSLKAEENRKLQKMK--DEQHQK 247
+L E +R R W R ++ + E+ R+ Q++K E+ ++
Sbjct: 442 RREQRLKREQEER----------------RDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 248 SELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQ 292
L+L+ +++ +++ + Q R RL+ + + L+Q
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Score = 52.8 bits (125), Expect = 4e-07
Identities = 52/214 (24%), Positives = 94/214 (43%), Gaps = 24/214 (11%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRL--GGSQSETEVRQKQQLQLMQSKYK 133
R+ E QR E LE+ Q R + R L G QSE + R +Q+ + + +
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEF 193
+ ++E R ++ AEE +LQ K + E+ E+ +R + R RE +Q + E
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKL-----QKMKDEQHQKS 248
++ E + + W R+++ +E KL Q+ ++ Q ++
Sbjct: 234 QDRVFQEEEE-----------------KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
Query: 249 ELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 282
+L +L+RQ+ +ER + Q + R L R Q
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
Score = 49.7 bits (117), Expect = 3e-06
Identities = 44/192 (22%), Positives = 93/192 (48%), Gaps = 6/192 (3%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
+Q EQ+L E+ ++ +P R + + + + +++ QL+Q +Q+L+R+
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNT 199
E R +E E Q+++ +RE+ EE++ ++ L R+ FRE +Q + +L
Sbjct: 1688 ERDRKFREEE----QQLRRQERERKFLQEEQQLRRQELERK-FREEEQLRQETEQEQLRR 1742
Query: 200 ESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 259
+ R + P+ RD K E +L++ ++EQ +S+ + K +++E
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDR-KFREEEQLRQEREEQQLRSQESDRKFREEE 1801
Query: 260 QERAKIHQTEHR 271
Q R + + + R
Sbjct: 1802 QLRQEREEQQLR 1813
Score = 48.5 bits (114), Expect = 7e-06
Identities = 46/211 (21%), Positives = 104/211 (49%), Gaps = 26/211 (12%)
Query: 76 RRNEIQRIAEQELAN-------LEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLM 128
+++E+Q+ EQ L E+ ++ + + +L G + ET RQ+ + Q
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 129 QSKYKQK----LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEK--KRLQENLRREAF 182
+ + Q+ L REE + +++ E + ++ + +Q+E+ L E+ KR ++ L R+ +
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ-Y 1140
Query: 183 REHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKD 242
RE ++ + E +L E P++ Q R + + L+ EE + L++ ++
Sbjct: 1141 REEEEVQQEE--EQLLREEPEKRRRQEL---------ERQYREEEELQQEEEQLLREEQE 1189
Query: 243 EQHQKSELLELKRQQ-QEQERAKIHQTEHRR 272
++ Q+ E + ++ Q Q+R + ++ E +R
Sbjct: 1190 KRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Score = 46.2 bits (108), Expect = 4e-05
Identities = 53/225 (23%), Positives = 103/225 (45%), Gaps = 19/225 (8%)
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANL-EKWKEQNRAKPVH----LVPRRLGGSQS 115
+R T + + E+Q+ EQ L EK + Q R + L +
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSN-KLEEKKRLQ 174
E E R++Q+L+ Q + ++++++EE +++E E+ Q+++ RE+ + EE++ L+
Sbjct: 1127 EREKRRRQELE-RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDS---LKA 231
E + +QY+ E L + + R Q + Q + A RD+ K
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP-EKENAVRDNKVYCKG 1244
Query: 232 EENRKLQKMKDEQ----HQKSELLELKRQQQEQERAKIHQTEHRR 272
EN + ++++D Q + +L L +QQE++R + E RR
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR----EQERRR 1285
Score = 46.2 bits (108), Expect = 4e-05
Identities = 64/275 (23%), Positives = 123/275 (44%), Gaps = 46/275 (16%)
Query: 38 EDQREGL----EAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQR-----IAEQEL 88
EDQR L E + R++ V+ R + + + R + Q+ + EQ+
Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 89 ANLE----KWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQ-LQLMQSKYKQKLKREESVR 143
+ E +W++++R P R +++ R+ Q+ QL++ + ++K +R+E+ R
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 144 IKKEAE----EAELQKMKAIQREKSNK-------------LEEKKRLQENLRREAF-REH 185
+E E E E Q ++ +R++ + LEE++RL+ R F +E
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Query: 186 QQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDS----LKAEENRKL---- 237
QQ + E +L + DR + Q S R +R+ + E RK
Sbjct: 1397 QQLRCQEREQQLR-QDRDRKFREEE---QQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Query: 238 QKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 272
Q+++ E+H+K E ++ QE+E ++H+ E R
Sbjct: 1453 QQLRQERHRK--FREEEQLLQEREEQQLHRQERDR 1485
Score = 45.4 bits (106), Expect = 6e-05
Identities = 62/261 (23%), Positives = 111/261 (42%), Gaps = 27/261 (10%)
Query: 39 DQREGLEAAPKGPSRESVVHAGQ--RRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96
+Q E LE K RE V Q RR P RR ++ + EQE E+ ++
Sbjct: 593 EQEERLEQRLK---REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE----ERRQQ 645
Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES----VRIKKEAEEAE 152
Q R + +RL + E + Q+ + + + + +Q+L EE RIK + +
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705
Query: 153 LQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVC 212
Q +++ + +K+ + R QE RR R+ Q+ K S+L + +R+ Q
Sbjct: 706 WQ-LESEADARQSKVYSRPRKQEGQRR---RQEQEEKRRRRESELQWQEEERAHRQQQ-- 759
Query: 213 GPQSSTWARSWAYRDSLKAEENRKLQKMKD--EQHQKSELLELKRQQQEQ-----ERAKI 265
+ +W ++ K+E R+ + + ++ +L +RQQ+EQ E K
Sbjct: 760 -EEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKE 818
Query: 266 HQTEHRRVNNAFLDRLQGKSQ 286
+ RR L L+ + Q
Sbjct: 819 QRRRQRREREKELQFLEEEEQ 839
Score = 44.3 bits (103), Expect = 1e-04
Identities = 45/204 (22%), Positives = 94/204 (46%), Gaps = 23/204 (11%)
Query: 79 EIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK--- 135
++ R ++ E+ ++ + K + +L G + E RQ+++ + + + Q+
Sbjct: 942 QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Query: 136 -LKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---KKRLQENLRREAFREHQQYKTA 191
L REE + +++ E + +K +Q+E+ L E K+RLQE R +RE ++ +
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE--RERQYREEEELQQE 1059
Query: 192 EFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDE---QHQKS 248
E +L E + Q R + + L+ EE + L++ ++ Q ++
Sbjct: 1060 E--EQLLGEERETRRRQEL---------ERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 249 ELLELKRQQQEQERAKIHQTEHRR 272
+ E + QQE+E+ + E RR
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRR 1132
Score = 43.5 bits (101), Expect = 2e-04
Identities = 54/243 (22%), Positives = 104/243 (42%), Gaps = 25/243 (10%)
Query: 36 PVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWK 95
P+ +QRE R+ Q+R + +R +R E+EL LE+ +
Sbjct: 789 PLREQRE----------RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Query: 96 EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVR----IKKEAEEA 151
+ R + + G Q + E R+ Q+ Q K++ +L+ E R K A +
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQE-QRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTE--SPDRSACQS 209
+L+K + + +E+ +L+ ++R E RR+ + +QY+ E L + + +R +
Sbjct: 898 QLRKEQQLLQEEEEELQREER--EKRRRQ--EQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 210 AVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 269
Q + + L EE K ++ + E+ + E + QQE+E+ + E
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE----EELQQEEEQLLREERE 1009
Query: 270 HRR 272
RR
Sbjct: 1010 KRR 1012
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/202 (18%), Positives = 95/202 (47%), Gaps = 7/202 (3%)
Query: 74 INRRNEIQRIAEQELANLEKWKE-QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKY 132
+ R+ ++ E+EL + E+ ++ + + R + E ++R +++ Q ++
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 133 KQKLKREESVRIKKEAEEAELQKMKAIQREKSNK--LEEKKRLQENLRREAFREHQQYKT 190
+K + EE ++E + ++ + ++R++ + LEE+++L++ R+ FRE +Q
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK-FREEEQLLQ 1471
Query: 191 AEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSEL 250
+L+ + DR + Q R +R+ + + + +++EQ +
Sbjct: 1472 EREEQQLHRQERDRKFLEEE---QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 251 LELKRQQQEQERAKIHQTEHRR 272
+ K Q+EQ+ + + + RR
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRR 1550
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/196 (21%), Positives = 97/196 (49%), Gaps = 11/196 (5%)
Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQ--SETEVRQKQQLQLMQSKYKQKLKRE 139
R+ EQ++ E+ E+ + + R+ G Q E + + ++ QL+Q + +Q+L R+
Sbjct: 1582 RLEEQKVRRQEQ--ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ 1639
Query: 140 ESVR--IKKEAEEAELQKMKAIQREKSNKL-EEKKRLQENLRREAFREHQQYKTAEFLSK 196
E R +++E + ++ + ++ ++ K EE++ LQE ++ R+ + K E +
Sbjct: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ 1699
Query: 197 LNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQ 256
L + +R Q + R + + L+ +E + Q + E+++K +LE ++
Sbjct: 1700 LRRQERERKFLQEEQ-QLRRQELERKFREEEQLR-QETEQEQLRRQERYRK--ILEEEQL 1755
Query: 257 QQEQERAKIHQTEHRR 272
+ E+E ++ + E R
Sbjct: 1756 RPEREEQQLRRQERDR 1771
Score = 39.7 bits (91), Expect = 0.003
Identities = 52/223 (23%), Positives = 100/223 (44%), Gaps = 27/223 (12%)
Query: 76 RRNEIQRI---AEQELANLEKWKE--QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQS 130
RR E +R EQ+L E+ ++ Q+R + ++L + + + R+++Q Q
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 131 KYKQKLKREESVRIKKEA----EEAELQKMKAIQREKSNK----LEEKKRLQENLRREAF 182
+ ++ L+ E+ +R ++ EE LQ+ + Q + + LEE+++L+ R F
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF 1503
Query: 183 REHQ------QYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRK 236
RE + + K E +L+ + R Q + + RD K E +
Sbjct: 1504 REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR-KFREEEQ 1562
Query: 237 LQKMKDEQH-------QKSELLELKRQQQEQERAKIHQTEHRR 272
L++ ++EQ +K L E K ++QEQER + + R
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR 1605
Score = 37.7 bits (86), Expect = 0.013
Identities = 39/172 (22%), Positives = 77/172 (44%), Gaps = 10/172 (5%)
Query: 31 QGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELAN 90
Q +L E R+ LE P RE Q R + + + E Q++ QE
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDR 1795
Query: 91 LEKWKEQNRAKPVHLVPRRLGGSQSETEVR-QKQQLQLMQSKYKQKLKREESVRIKK--- 146
+ +EQ R + ++L Q + + R +++QLQL + + + + +R+ R ++
Sbjct: 1796 KFREEEQLRQEREE---QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA 1852
Query: 147 --EAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSK 196
E E Q++ + +K + E+K +E++RR+ E + + E S+
Sbjct: 1853 TQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 37.0 bits (84), Expect = 0.022
Identities = 47/218 (21%), Positives = 91/218 (41%), Gaps = 29/218 (13%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK--- 133
R E Q++ QE +EQ + H R+ + + R++QQL + K
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERH---RKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 134 --QKLKREESVRIKKEAE-------------EAELQKM----KAIQREKSNKLEEKKRLQ 174
Q+L+R+E R +E E E +L + K +Q E+ + +E+ + +
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEEN 234
R FRE +Q + +L+ + DR + + L+ +E
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 235 RKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 272
+ Q+++ E+ +K E ++ QE+E ++H+ E R
Sbjct: 1610 Q--QQLRQERDRK--FREDEQLLQEREEQQLHRQERDR 1643
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 58.5 bits (140), Expect = 7e-09
Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 12/200 (6%)
Query: 10 SGLGASPASRPTRDPQDPSGRQGELSPVEDQREGL----EAAPKGPSRESVVHAGQRRTS 65
S ASPA P P P+ Q E P E + AP P S AG
Sbjct: 539 SAAPASPAPSPAPSPT-PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDRE 597
Query: 66 AYTLIAPNINRRNEIQRIAEQELANLE-----KWKEQNRAKPVHLVPRRLGGSQ--SETE 118
T + R+ QR E++ L+ + +E+ A+ R ++ E E
Sbjct: 598 EATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQE 657
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178
R+K Q + + + QK K E R ++EAE L++ K Q+++ + E +KRL+E ++
Sbjct: 658 AREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMK 717
Query: 179 REAFREHQQYKTAEFLSKLN 198
R E + K + + N
Sbjct: 718 RTRKSEVSETKQKQDSKEAN 737
Score = 36.6 bits (83), Expect = 0.029
Identities = 37/173 (21%), Positives = 79/173 (45%), Gaps = 18/173 (10%)
Query: 23 DPQDPSGRQGEL-SPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNI------- 74
+P+ PSG+ G +P +++ EA +GP+ ++ R + +P
Sbjct: 67 EPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSP 126
Query: 75 NRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ 134
+ E+++ E+ L K + + RAK +L ++ + E + + ++ QL + +
Sbjct: 127 PTKQEVKKAGERH--KLAKERREERAK--YLAAKKAVWLEKEEKAKALREKQLQERR--- 179
Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQ 187
+R E R+K E A L++ + + EK NK + +Q ++++ QQ
Sbjct: 180 --RRLEEQRLKAEQRRAALEERQRQKLEK-NKERYEAAIQRSVKKTWAEIRQQ 229
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 56.6 bits (135), Expect = 3e-08
Identities = 59/208 (28%), Positives = 95/208 (45%), Gaps = 23/208 (11%)
Query: 79 EIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEV----RQKQQLQLMQSKY 132
E +R+ EQ L LE+ W+E R + L+ G + E R++QQ L +
Sbjct: 244 EKRRLEEQRLQALERRLWEENRRQE---LLEEEGEGQEPPLEAERAPREEQQRSLEAPGW 300
Query: 133 KQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192
+ +RE R + EAEE + Q E+ +LEE RL+E R +E ++ + AE
Sbjct: 301 EDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRR----QEEEEGRCAE 356
Query: 193 FLSKLNTES----PDRSACQSAVCGP----QSSTWARSWAYRDSLKAEENRKLQKMKDEQ 244
L + E + ++ V GP + + R A + L EE ++D +
Sbjct: 357 ELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWR 416
Query: 245 HQKSELL-ELKRQQQEQERAKIH-QTEH 270
Q SELL + + + ++QER K Q EH
Sbjct: 417 GQLSELLNDFEERLEDQERLKPEGQREH 444
Score = 37.7 bits (86), Expect = 0.013
Identities = 45/189 (23%), Positives = 71/189 (37%), Gaps = 28/189 (14%)
Query: 11 GLGASPASRPTRDPQDPSGRQGELSPVED-------QREGLEAAPKGPSRESVVHAGQRR 63
G G P R P++ R E ED +RE LEA + ++ A +RR
Sbjct: 274 GEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERR 333
Query: 64 TSAYTLIAPNINRRNE-----IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETE 118
R+ E + + QE E W+E Q E E
Sbjct: 334 RLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELE---------------QQEAE 378
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178
V+ + L ++ ++ EE + ++E +A L+ + E N EE+ QE L+
Sbjct: 379 VQGPPEA-LEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLK 437
Query: 179 REAFREHQQ 187
E REH +
Sbjct: 438 PEGQREHSE 446
Score = 34.3 bits (77), Expect = 0.14
Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 41/201 (20%)
Query: 17 ASRPTRDPQDPSGRQGELSPVEDQREGLEAAP---KGPSRESVVHAGQRRTSAYTLIAPN 73
A RP +P +PS E S D+R P KG R+ A +R+ ++ L A
Sbjct: 993 AGRPDPEPSEPSKEDQESS---DRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQ 1049
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+ ++ +E KP+ L GS+ +V Q L + + K
Sbjct: 1050 QEKPSQTPEAGRKE-------------KPMLQSRHSLDGSKLTEKVETAQPLWITLALQK 1096
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQRE--------------------KSNKLEEKKRL 173
QK RE+ ++ + E ++ + + +E KS L E+KR
Sbjct: 1097 QKGFREQQATREERKQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEEKRP 1156
Query: 174 QENLRREAFREHQQYKTAEFL 194
+ + R RE Q K A L
Sbjct: 1157 ETAVSRLERRE--QLKKANTL 1175
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 55.1 bits (131), Expect = 8e-08
Identities = 53/244 (21%), Positives = 106/244 (43%), Gaps = 18/244 (7%)
Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96
+ +Q + E K E + +R+ + R + ++I EQE + W++
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK---KMWRQ 456
Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQK 155
+ + + + E RQ++++ + ++QK K E+ +I+K+ E+ Q+
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 156 MKAI--------QREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSAC 207
K Q EK + EEK R QE + RE + H+Q K E + E D+
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE--EEKRQEQEDKMWR 574
Query: 208 QSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQ 267
Q Q + W + ++ +E ++ ++ + Q+ ++ E + + QEQE KI +
Sbjct: 575 QEEKIREQEE---KVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE-KIRE 630
Query: 268 TEHR 271
E +
Sbjct: 631 QEEK 634
Score = 54.3 bits (129), Expect = 1e-07
Identities = 48/199 (24%), Positives = 93/199 (46%), Gaps = 40/199 (20%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
++I EQE EK +EQ RR E E + ++Q ++M K ++K++R+E
Sbjct: 321 EKIREQE----EKIREQEEKM------RRQEEMMWEKEEKMRRQEEMMWEK-EEKMRRQE 369
Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTE 200
+ +KE + ++M + EK +LEEK QE +R + + ++ K E + E
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 201 SPDRSACQSAVCGPQSSTWARSWAYRDSLK------AEENRKLQKMKDEQHQKSELL-EL 253
A+ W + ++ E+ +K+ + +++ H++ ++ E
Sbjct: 430 -------------------AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 254 KRQQQEQ---ERAKIHQTE 269
KRQ+QE+ + KIH+ E
Sbjct: 471 KRQEQEEMWRQEEKIHEQE 489
Score = 46.2 bits (108), Expect = 4e-05
Identities = 49/221 (22%), Positives = 107/221 (48%), Gaps = 28/221 (12%)
Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123
+ ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ +
Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 293
Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183
L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E +
Sbjct: 294 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 347
Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDE 243
E + + E + E ++ Q + + R ++ + E+ K+++++++
Sbjct: 348 EEKMRRQEEMM----WEKEEKMRRQEEMMWEKEEKMRR----QEEMMWEKEEKIRELEEK 399
Query: 244 QHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 284
H++ ++ E + ++QE+E KI + E R+ A + R + K
Sbjct: 400 MHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 438
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/202 (23%), Positives = 91/202 (45%), Gaps = 21/202 (10%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEV-RQKQQLQLMQSKYKQKLKRE 139
++I EQE E W+E+ + + + E ++ RQ+++++ + K ++E
Sbjct: 538 EKIREQE----EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV---WRQE 590
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFRE--HQQYKTAEFLSKL 197
E +R ++E + + +KM Q EK + EEK + QE RE + Q+ T E K+
Sbjct: 591 EKIREQEEKRQEQEEKMWK-QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 198 NTESPDRSACQSAVCGPQSSTWARSWAYRDSLK-----AEENRKLQKMKDEQHQK----- 247
+ + + + + W + R+ K E+ R+ ++M EQ +K
Sbjct: 650 GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 709
Query: 248 SELLELKRQQQEQERAKIHQTE 269
++ E + + QEQE Q E
Sbjct: 710 EKMCEQEEKMQEQEEKMRRQEE 731
Score = 42.0 bits (97), Expect = 7e-04
Identities = 42/165 (25%), Positives = 78/165 (47%), Gaps = 18/165 (10%)
Query: 109 RLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLE 168
RL Q E RQ++++Q + K +++ EE +R ++E + +KM+ Q E + E
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQEEKMRR-QEEMMWEKE 348
Query: 169 EKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRD- 227
EK R QE + E +E + + E + E ++ Q + W + R+
Sbjct: 349 EKMRRQEEMMWE--KEEKMRRQEEMM----WEKEEKMRRQ------EEMMWEKEEKIREL 396
Query: 228 SLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 272
K E K+++ ++E+ Q+ E + + ++QEQE Q E R
Sbjct: 397 EEKMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440
Score = 38.9 bits (89), Expect = 0.006
Identities = 39/185 (21%), Positives = 91/185 (49%), Gaps = 19/185 (10%)
Query: 81 QRIAEQELANLEK-WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++I EQE EK W+++ + + + + E + ++Q + +Q + ++ ++E
Sbjct: 577 EKIREQE----EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNT 199
E +R ++E + + +KM Q EK + EEK + QE +R+ ++ + E K
Sbjct: 633 EKIREQEEMTQEQEEKM-GEQEEKMCEQEEKMQEQE---ETMWRQEEKIREQE---KKIR 685
Query: 200 ESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELL---ELKRQ 256
E ++ Q + Q + W + + E+ K+Q+ +++ ++ E + E++ +
Sbjct: 686 EQEEKIREQEEMMQEQEE---KMWEQEEKM-CEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
Query: 257 QQEQE 261
QQE++
Sbjct: 742 QQEEK 746
Score = 32.3 bits (72), Expect = 0.54
Identities = 29/156 (18%), Positives = 70/156 (44%), Gaps = 15/156 (9%)
Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174
T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEEN 234
+ +A +H + +KL + ++ W R ++ +
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQV------------EENELWNRLNQQQEEKMWRQE 306
Query: 235 RKLQKMKDE-QHQKSELLELKRQQQEQERAKIHQTE 269
K+Q+ +++ Q Q+ ++ E + + +EQE Q E
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 55.1 bits (131), Expect = 8e-08
Identities = 33/118 (27%), Positives = 61/118 (51%), Gaps = 7/118 (5%)
Query: 76 RRNEI-QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ 134
+R E+ QR+AE+ E+ + A+ +L E +R++++ + Q +
Sbjct: 511 KREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQ--- 567
Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192
+EE R+++EAE ++ K QRE+ +LE KKRL+E ++R E KT++
Sbjct: 568 ---KEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSD 622
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 11/134 (8%)
Query: 139 EESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198
EE+ R+ L + + + RE+ K E ++R QE L R+ E Q E ++
Sbjct: 477 EEATRL--------LAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRRE 528
Query: 199 TESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQ 258
ES A Q+ Q A A R+ EE + Q+ K+E+ + E E RQ++
Sbjct: 529 EESRRLEAEQAREKEEQLQRQAEERALRE---REEAERAQRQKEEEARVREEAERVRQER 585
Query: 259 EQERAKIHQTEHRR 272
E+ + Q R
Sbjct: 586 EKHFQREEQERLER 599
Score = 37.0 bits (84), Expect = 0.022
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 14/169 (8%)
Query: 127 LMQSKYKQKLKREESVRIKKEAEEAELQKMKAI-----QREKSNKLEEKKRLQENLRREA 181
L + + + +RE+ R ++E EE E QK + + + + + EE +RL+ RE
Sbjct: 483 LAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQARE- 541
Query: 182 FREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMK 241
+E Q + AE + E +R+ Q AR + ++ E + Q+ +
Sbjct: 542 -KEEQLQRQAEERALREREEAERAQ-------RQKEEEARVREEAERVRQEREKHFQREE 593
Query: 242 DEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGL 290
E+ ++ + LE ++ + A +T +R + L G ++ L
Sbjct: 594 QERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSAL 642
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 53.9 bits (128), Expect = 2e-07
Identities = 46/207 (22%), Positives = 101/207 (48%), Gaps = 17/207 (8%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+N++ E + ++E +++W+E+ + + + R E E + ++Q ++M K +
Sbjct: 294 LNQQQEEKMWRQEE--KIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEK-E 348
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQ 187
+K++R+E + +KE + L++M + EK +LEEK R QE R+E + +Q
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQK 247
K E +K+ + + + + W + + K E K Q+ ++ Q+
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 248 SELLELKRQQQE--QERAKIHQTEHRR 272
++ R+Q+E +++ K+H+ E R
Sbjct: 469 EKI----REQEEIWRQKEKMHEQEKIR 491
Score = 47.4 bits (111), Expect = 2e-05
Identities = 49/212 (23%), Positives = 96/212 (45%), Gaps = 24/212 (11%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK--- 133
+ E R E+++ EK +EQ + R E E RQ+Q+ ++ + + K
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIR-------EQEKRQEQEAKMWRQEEKIRE 427
Query: 134 --QKLKREESVRIKKEAEEAELQKM----KAIQREKSNKLEEKKRLQENLRREAFREHQQ 187
+K++ +E ++E + E +K+ K ++E+ + EEK R QE + R+ + H+Q
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487
Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDS-----LKAEENRKLQKMKD 242
K + K+ + + + + W + R+ + E+ R+ ++M
Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ 547
Query: 243 EQHQKSELLELKRQQQEQER---AKIHQTEHR 271
EQ +K E K Q+QE+ R KI + E +
Sbjct: 548 EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/237 (19%), Positives = 100/237 (42%), Gaps = 24/237 (10%)
Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96
+ +Q + E K E + +R+ + R + ++I EQE + W++
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK---KMWRQ 442
Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQS--KYKQKLKREESVRIKKEAEEAELQ 154
+ + + + E RQ+++++ + + K+K+ +E +R ++E + +
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502
Query: 155 KMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGP 214
KM Q EK + EEK QE RE Q+ K E K+ E + Q G
Sbjct: 503 KMHD-QEEKIREQEEKMWRQEEKIRE-----QEEKIREQEEKIR-EQEEMMQEQEEKMGE 555
Query: 215 QSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 271
Q K +E K+++ +++ ++ E + ++++ ++ KI + E +
Sbjct: 556 QEE------------KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Score = 42.0 bits (97), Expect = 7e-04
Identities = 43/194 (22%), Positives = 95/194 (48%), Gaps = 16/194 (8%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
+++ EQE ++ K + + +H ++ Q E RQ+++++ + K RE+
Sbjct: 482 EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR-EQEEKMWRQEEKIREQEEKI-----REQ 535
Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFRE--HQQYKTAEFLSKLN 198
+I+++ E + Q+ K ++E+ + +EK R QE RE + Q+ K E K+
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI- 594
Query: 199 TESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELL--ELKRQ 256
E ++ Q + Q + W + + E+ K+Q+ +++ ++ E + + R
Sbjct: 595 WEQEEKIREQEEMMQEQEE---KMWEQEEKM-CEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
Query: 257 QQEQERAKIHQTEH 270
+Q++E+ + HQ EH
Sbjct: 651 RQQEEKMQEHQ-EH 663
Score = 41.6 bits (96), Expect = 9e-04
Identities = 48/223 (21%), Positives = 102/223 (45%), Gaps = 46/223 (20%)
Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123
+ ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ +
Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 293
Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183
L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E +
Sbjct: 294 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 347
Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYR--DSLKAEENRKLQKMK 241
E + + E + W + R + + E+ K+++++
Sbjct: 348 EEKMRRQEEMM------------------------WEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 242 DEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 284
++ H++ ++ E + ++QE+E KI + E R+ A + R + K
Sbjct: 384 EKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 424
Score = 35.4 bits (80), Expect = 0.064
Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 19/134 (14%)
Query: 77 RNEIQRIAEQE---LANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
R + ++I EQE EK EQ RR E E + ++Q + ++ + +
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 134 QKLKREESVRIKKEAEEAELQKM------KAIQREKSNKLEEKKRLQE----------NL 177
+ ++EE +R ++E + + +KM Q EK + EEK R QE
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652
Query: 178 RREAFREHQQYKTA 191
+ E +EHQ++ A
Sbjct: 653 QEEKMQEHQEHLEA 666
Score = 32.3 bits (72), Expect = 0.54
Identities = 29/156 (18%), Positives = 70/156 (44%), Gaps = 15/156 (9%)
Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174
T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEEN 234
+ +A +H + +KL + ++ W R ++ +
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQV------------EENELWNRLNQQQEEKMWRQE 306
Query: 235 RKLQKMKDE-QHQKSELLELKRQQQEQERAKIHQTE 269
K+Q+ +++ Q Q+ ++ E + + +EQE Q E
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/99 (21%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R + ++I EQE EK +EQ ++G + + + ++K + Q + + +++
Sbjct: 526 REQEEKIREQE----EKIREQEEMMQEQ--EEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Query: 137 KREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQE 175
RE+ +I+++ E+ Q+ K ++E+ + +E+K ++
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/212 (23%), Positives = 98/212 (46%), Gaps = 21/212 (9%)
Query: 73 NINRRNEI-----QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL 127
N+ R+ E Q++ E + LE+ K + + ++ R Q + E +++ + +
Sbjct: 544 NLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 603
Query: 128 MQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQ 187
Q K + +EE + +K ++A +KM+ ++ + + EE +RL+ + E R HQ
Sbjct: 604 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQE-EEARRLRWLQQEEEERRHQ- 661
Query: 188 YKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQH 245
E L K E + R A ++ Q R R+ + E+ R+ Q+ ++++
Sbjct: 662 ----ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717
Query: 246 Q--------KSELLELKRQQQEQERAKIHQTE 269
Q + E L+ +R+ QE+E+A Q E
Sbjct: 718 QLAEQERRREQERLQAERELQEREKALRLQKE 749
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/187 (23%), Positives = 86/187 (45%), Gaps = 27/187 (14%)
Query: 81 QRIAEQEL---ANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLK 137
+R+AE++ A +K +E + RRL Q E E R+ Q+L L + K +++ +
Sbjct: 616 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL-LQKKKEEEQER 674
Query: 138 REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKL 197
++ K+ AE+ E ++ + +RE+ + E+++R QE RRE R+ + + +L
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERR-EQERREQE--RREQERQLAEQERRREQERL 731
Query: 198 NTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQ 257
E R R+ + +LQ+ +E+ +K E L +Q
Sbjct: 732 QAE--------------------RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 771
Query: 258 QEQERAK 264
++E+ K
Sbjct: 772 LQEEQEK 778
Score = 42.4 bits (98), Expect = 5e-04
Identities = 34/159 (21%), Positives = 79/159 (49%), Gaps = 6/159 (3%)
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178
+R+K++ + ++ + ++ KR +K + EE + ++A +R + K E+KK++++
Sbjct: 545 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 604
Query: 179 R--EAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRK 236
+ E + ++ + AE +K + ++ + + R W ++ +
Sbjct: 605 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR-WLQQEEEERRHQEL 663
Query: 237 LQKMKDEQHQK-SELLELKR--QQQEQERAKIHQTEHRR 272
LQK K+E+ ++ + E KR +Q+EQER + + E R
Sbjct: 664 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 702
Score = 40.8 bits (94), Expect = 0.002
Identities = 62/280 (22%), Positives = 121/280 (43%), Gaps = 33/280 (11%)
Query: 7 VVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSR-----ESVVHAGQ 61
+ NS PA+ P+ PS Q E DQ +G P+ R ++V +
Sbjct: 408 IANSTPNPKPAAS---SPETPSAGQQEAKT--DQADGPREPPQSARRKRSYKQAVSELDE 462
Query: 62 RRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQ 121
+ + P ++ A + + L + + + + P S ++ +++
Sbjct: 463 EQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKR 522
Query: 122 KQQLQLMQ--SKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---------K 170
L++ S +++ +R E++R K+EAE+ QK ++ +K +LEE +
Sbjct: 523 NTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQK---VEEDKRRRLEEVKLKREERLR 579
Query: 171 KRLQENLRREAFREHQ----QYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYR 226
K LQ R E +E + + K A+ K +R A + A + A R
Sbjct: 580 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 639
Query: 227 DSLKAEENRKLQ--KMKDEQHQKSELLELKRQQQEQERAK 264
+ EE R+L+ + ++E+ + ELL+ K++++EQER +
Sbjct: 640 K--QEEEARRLRWLQQEEEERRHQELLQ-KKKEEEQERLR 676
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 17/122 (13%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+ + E +R+AEQ +EQ R + R + E E R++Q+ QL + +
Sbjct: 675 LRKAAEAKRLAEQ--------REQERREQERREQERREQERREQE-RREQERQLAEQE-- 723
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREK-SNKLEEKKRL--QENLRREAFREHQQYKT 190
+R E R++ E E E +K +Q+E+ +LEEKK+ Q+ L +E Q+ K
Sbjct: 724 ---RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780
Query: 191 AE 192
E
Sbjct: 781 KE 782
Score = 36.2 bits (82), Expect = 0.037
Identities = 23/134 (17%), Positives = 65/134 (48%), Gaps = 1/134 (0%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
+ E + QEL +K +EQ R + R + E +++++ + + + +++
Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 711
Query: 137 KREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSK 196
+RE+ ++ ++ E ++++A +RE + + + +E L+RE + ++ + +
Sbjct: 712 RREQERQLAEQERRREQERLQA-ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 770
Query: 197 LNTESPDRSACQSA 210
E ++ A ++A
Sbjct: 771 QLQEEQEKKAKEAA 784
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/212 (23%), Positives = 98/212 (46%), Gaps = 21/212 (9%)
Query: 73 NINRRNEI-----QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL 127
N+ R+ E Q++ E + LE+ K + + ++ R Q + E +++ + +
Sbjct: 540 NLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 599
Query: 128 MQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQ 187
Q K + +EE + +K ++A +KM+ ++ + + EE +RL+ + E R HQ
Sbjct: 600 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQE-EEARRLRWLQQEEEERRHQ- 657
Query: 188 YKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQH 245
E L K E + R A ++ Q R R+ + E+ R+ Q+ ++++
Sbjct: 658 ----ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713
Query: 246 Q--------KSELLELKRQQQEQERAKIHQTE 269
Q + E L+ +R+ QE+E+A Q E
Sbjct: 714 QLAEQERRREQERLQAERELQEREKALRLQKE 745
Score = 45.4 bits (106), Expect = 6e-05
Identities = 42/180 (23%), Positives = 89/180 (49%), Gaps = 9/180 (5%)
Query: 99 RAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ-KLKREESVRIKKEAEEAELQKMK 157
R P+ + P+ + E R+++ QL + K ++ K +R E V++K+E E + ++
Sbjct: 522 RNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE--ERLRKVLQ 579
Query: 158 AIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQ 215
A +R + K E+KK++++ + E + ++ + AE +K + ++ +
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 216 SSTWARSWAYRDSLKAEENRKLQKMKDEQHQK-SELLELKR--QQQEQERAKIHQTEHRR 272
+ R W ++ + LQK K+E+ ++ + E KR +Q+EQER + + E R
Sbjct: 640 EARRLR-WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/187 (23%), Positives = 86/187 (45%), Gaps = 27/187 (14%)
Query: 81 QRIAEQEL---ANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLK 137
+R+AE++ A +K +E + RRL Q E E R+ Q+L L + K +++ +
Sbjct: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL-LQKKKEEEQER 670
Query: 138 REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKL 197
++ K+ AE+ E ++ + +RE+ + E+++R QE RRE R+ + + +L
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERR-EQERREQE--RREQERQLAEQERRREQERL 727
Query: 198 NTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQ 257
E R R+ + +LQ+ +E+ +K E L +Q
Sbjct: 728 QAE--------------------RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
Query: 258 QEQERAK 264
++E+ K
Sbjct: 768 LQEEQEK 774
Score = 43.1 bits (100), Expect = 3e-04
Identities = 64/278 (23%), Positives = 121/278 (43%), Gaps = 33/278 (11%)
Query: 7 VVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSR-----ESVVHAGQ 61
+ NS PA+ P+ PS Q E DQ +G P+ R ++V +
Sbjct: 408 IANSTPNPKPAAS---SPETPSAGQQEAKT--DQADGPREPPQSARRKRSYKQAVSELDE 462
Query: 62 RRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQ 121
+ + P ++ A + + L + + + + P S ++ +++
Sbjct: 463 EQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKR 522
Query: 122 KQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---------KKR 172
L+ M K K++ +R E++R K+EAE+ QK ++ +K +LEE +K
Sbjct: 523 NTPLR-MDPKEKER-QRLENLRRKEEAEQLRRQK---VEEDKRRRLEEVKLKREERLRKV 577
Query: 173 LQENLRREAFREHQ----QYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDS 228
LQ R E +E + + K A+ K +R A + A + A R
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRK- 636
Query: 229 LKAEENRKLQ--KMKDEQHQKSELLELKRQQQEQERAK 264
+ EE R+L+ + ++E+ + ELL+ K++++EQER +
Sbjct: 637 -QEEEARRLRWLQQEEEERRHQELLQ-KKKEEEQERLR 672
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 17/122 (13%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+ + E +R+AEQ +EQ R + R + E E R++Q+ QL + +
Sbjct: 671 LRKAAEAKRLAEQ--------REQERREQERREQERREQERREQE-RREQERQLAEQE-- 719
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREK-SNKLEEKKRL--QENLRREAFREHQQYKT 190
+R E R++ E E E +K +Q+E+ +LEEKK+ Q+ L +E Q+ K
Sbjct: 720 ---RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 776
Query: 191 AE 192
E
Sbjct: 777 KE 778
Score = 36.2 bits (82), Expect = 0.037
Identities = 23/134 (17%), Positives = 65/134 (48%), Gaps = 1/134 (0%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
+ E + QEL +K +EQ R + R + E +++++ + + + +++
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
Query: 137 KREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSK 196
+RE+ ++ ++ E ++++A +RE + + + +E L+RE + ++ + +
Sbjct: 708 RREQERQLAEQERRREQERLQA-ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 766
Query: 197 LNTESPDRSACQSA 210
E ++ A ++A
Sbjct: 767 QLQEEQEKKAKEAA 780
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 53.1 bits (126), Expect = 3e-07
Identities = 45/206 (21%), Positives = 100/206 (48%), Gaps = 17/206 (8%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+N++ E + ++E +++W+E+ + + + R E E + ++Q ++M K +
Sbjct: 355 LNQQQEEKMWRQEE--KIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEK-E 409
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQ 187
+K++R+E + +KE + ++M + EK +LEEK R QE R+E + +Q
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQK 247
K E +K+ + + + + W + + K E K Q+ ++ Q+
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 248 SELLELKRQQQE--QERAKIHQTEHR 271
++ R+Q+E +++ KIH+ E +
Sbjct: 530 EKI----REQEEIWRQKEKIHEQEEK 551
Score = 42.7 bits (99), Expect = 4e-04
Identities = 39/198 (19%), Positives = 92/198 (46%), Gaps = 9/198 (4%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135
+R E ++I EQE ++ K + + + ++ Q E RQ++++ Q K +++
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR-EQEEKMWRQEEKIH-EQEKIREE 516
Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQEN--LRREAFREHQQYKTAEF 193
KR+E + ++ E+ Q+ Q+EK ++ EEK R QE R+E Q+ K E
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ 576
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLEL 253
K+ + + + + ++ + E+ K+ + +++ ++ E ++
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKI-----REQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Query: 254 KRQQQEQERAKIHQTEHR 271
+ ++ ++ KI + E +
Sbjct: 632 QEEKMRRQEEKIREQEKK 649
Score = 41.6 bits (96), Expect = 9e-04
Identities = 48/223 (21%), Positives = 102/223 (45%), Gaps = 46/223 (20%)
Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123
+ ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ +
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 354
Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183
L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E +
Sbjct: 355 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 408
Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYR--DSLKAEENRKLQKMK 241
E + + E + W + R + + E+ K+++++
Sbjct: 409 EEKMRRQEEMM------------------------WEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 242 DEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 284
++ H++ ++ E + ++QE+E KI + E R+ A + R + K
Sbjct: 445 EKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 485
Score = 41.6 bits (96), Expect = 9e-04
Identities = 48/224 (21%), Positives = 96/224 (42%), Gaps = 43/224 (19%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQK 135
+ E R E+++ EK +EQ + Q E ++R++++ Q ++K ++Q+
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKR------------QEEEKIREQEKRQEQEAKMWRQE 483
Query: 136 LK-REESVRIKKEAEEAELQKMKAIQREKSN------------KLEEKKRLQENLRREAF 182
K RE+ +I+++ E+ Q+ K ++EK + EEK R QE + R+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 183 REHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEEN-------- 234
+ H+Q + + ++ Q Q + W + ++ +E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE---KVWRQEEKIREQEEKIREQEEK 600
Query: 235 -RKLQKMKDEQHQK-----SELLELKRQQQEQERAKIHQTEHRR 272
R+ ++M EQ +K ++ E + + QEQE Q E R
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/163 (19%), Positives = 78/163 (47%), Gaps = 25/163 (15%)
Query: 114 QSETEVRQKQQLQLMQSKYKQ---KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEK 170
Q E RQ+++++ + K ++ K++ +E + ++E + E ++ Q EK + EEK
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635
Query: 171 -KRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSL 229
+R +E +R + + +Q + ++ E + + W + +
Sbjct: 636 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE-----------------KMWEQEEKM 678
Query: 230 KAEENRKLQKMKDEQHQKSELL--ELKRQQQEQERAKIHQTEH 270
E+ K+Q+ +++ ++ E + + R +Q++E+ + HQ EH
Sbjct: 679 -CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ-EH 719
Score = 35.4 bits (80), Expect = 0.064
Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 19/131 (14%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R + ++I EQE E+ ++ + Q E RQ+++++ + K +++
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ- 653
Query: 137 KREESVRIKKEAEEAELQKM------KAIQREKSNKLEEKKRLQE----------NLRRE 180
EE +R ++E + + +KM Q EK + EEK R QE + E
Sbjct: 654 --EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
Query: 181 AFREHQQYKTA 191
+EHQ++ A
Sbjct: 712 KMQEHQEHLEA 722
Score = 32.3 bits (72), Expect = 0.54
Identities = 29/156 (18%), Positives = 70/156 (44%), Gaps = 15/156 (9%)
Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174
T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L
Sbjct: 260 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 319
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEEN 234
+ +A +H + +KL + ++ W R ++ +
Sbjct: 320 PQQQLQAEADHLGKELQSVSAKLQAQV------------EENELWNRLNQQQEEKMWRQE 367
Query: 235 RKLQKMKDE-QHQKSELLELKRQQQEQERAKIHQTE 269
K+Q+ +++ Q Q+ ++ E + + +EQE Q E
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 403
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 52.8 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 94/205 (45%), Gaps = 24/205 (11%)
Query: 89 ANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEA 148
ANL+K KE + ++ R + + RQ+ +L+L++ +Q + +E V ++
Sbjct: 267 ANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLR---EQHAREKEEVVLRCGQ 323
Query: 149 EEAELQKMKAIQREKSNKL---------EEKKRLQENLRREAFREHQ----------QYK 189
E AEL++ + EK+ ++ EK ENLR+E +HQ Q +
Sbjct: 324 EAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKE 383
Query: 190 TAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQ--KMKDEQHQK 247
AE ++L D++ + A+ +S A R+ L++E R L+ + K ++ +K
Sbjct: 384 LAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEK 443
Query: 248 SELLELKRQQQEQERAKIHQTEHRR 272
+ LEL+ Q E K E R
Sbjct: 444 EKQLELENLQASYEDLKAQSQEEIR 468
Score = 39.3 bits (90), Expect = 0.004
Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 33/204 (16%)
Query: 85 EQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRI 144
+QE+ LE Q AKP PR + + EV +L+Q K ++KL + I
Sbjct: 1496 QQEIQRLEGQLRQ-AAKPQPWGPRDSQQAPLDGEV------ELLQQKLREKLDEFNELAI 1548
Query: 145 KKEA-------EEAELQKMKAIQ---REKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194
+KE+ +E E+++++ + R+K +L+E+ Q+N+ + ++ + K + +
Sbjct: 1549 QKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQ-M 1607
Query: 195 SKLNTESPDRSACQSAVC----------GP--QSSTWARSWAYRDSLKAEENRKLQKMKD 242
S L S +S + C GP Q R+ R+S + +L+KMK
Sbjct: 1608 SSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEVTQRALLRRESEVLDLKEQLEKMKG 1667
Query: 243 EQHQKSE---LLELKRQQQEQERA 263
+ K+E L LK Q + A
Sbjct: 1668 DLESKNEEILHLNLKLDMQNSQTA 1691
Score = 39.3 bits (90), Expect = 0.004
Identities = 49/219 (22%), Positives = 89/219 (40%), Gaps = 20/219 (9%)
Query: 69 LIAPNINRRNE---IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL 125
L+ +++R + + + + A L+K KE+ +++ V L + + + + +QQL
Sbjct: 2766 LLTEQLSQRTQEACVHQDTQAHHALLQKLKEE-KSRVVDL--QAMLEKVQQQALHSQQQL 2822
Query: 126 QLMQSKYKQKLKREESVR--IKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183
+ K+ + L+RE+ V +K E QK RE LE ++ L+ E +
Sbjct: 2823 EAEAQKHCEALRREKEVSATLKSTVEALHTQK-----RELRCSLEREREKPAWLQAELEQ 2877
Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDE 243
H + K E + R QS Q W R L+ + R L K+K
Sbjct: 2878 SHPRLKEQEGRKAARRSAEAR---QSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQL 2934
Query: 244 QHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 282
Q +L + E +++H RR + D L+
Sbjct: 2935 QQTVRDL----ESKDEVPGSRLHLGSARRAAGSDADHLR 2969
Score = 35.8 bits (81), Expect = 0.049
Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 112 GSQSETEVRQKQQLQLMQSKYKQKLKRE--ESVRIKKEAEEAELQKMKAIQREKSNKLEE 169
GS+ +T + +K++ +QS Q +E ES+ ++ + + ++Q++K S+++EE
Sbjct: 1059 GSEKKTALHEKEETLRLQSAQAQPFHQEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEE 1118
Query: 170 KKRLQENLRREAFREHQQYKTAEFLSKL----NTESPDRSACQSAV 211
+ E L++ RE + + A LS L N +R A Q A+
Sbjct: 1119 CRSELEVLQQR--RERENREGANLLSMLKADVNLSHSERGALQDAL 1162
Score = 34.7 bits (78), Expect = 0.11
Identities = 34/164 (20%), Positives = 76/164 (46%), Gaps = 24/164 (14%)
Query: 118 EVRQKQQLQLMQSKYKQKL------------KREESVRIKKEAEEAELQKMKAIQREKSN 165
E K QL L+Q++ K+++ K + R+K + E+ + ++ Q+E +N
Sbjct: 674 ETEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDDLEKVKHNLIEDHQKELNN 733
Query: 166 KLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAY 225
K+ E +++E R+ +K + +L E+ ++ ++ + ++
Sbjct: 734 ----AKQKTELMKQEFQRKETDWKVMK--EELQREAEEKLTLMLLELREKAESEKQTIIN 787
Query: 226 RDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 269
+ L+ E R+LQ Q +++L+L+R EQ+ ++ Q E
Sbjct: 788 KFELREAEMRQLQ-----DQQAAQILDLERSLTEQQ-GRLQQLE 825
Score = 32.7 bits (73), Expect = 0.41
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 5/167 (2%)
Query: 107 PRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNK 166
P G + V++ LQLM ++ + +R+E ++A LQ+ + +
Sbjct: 844 PTAQDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARELQL 903
Query: 167 LEEKKRLQE-NLRREAFREHQQYK---TAEFLSKLNTESPDRSA-CQSAVCGPQSSTWAR 221
L+E+ + Q ++ E HQ TA SK R A Q+ + R
Sbjct: 904 LQERHQQQLLSVTAELEARHQAALGELTASLESKQGALLAARVAELQTKHAADLGALETR 963
Query: 222 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQT 268
+ DSL++ + Q +++E Q ELL ++Q ++ +HQT
Sbjct: 964 HLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLHQT 1010
Score = 32.3 bits (72), Expect = 0.54
Identities = 36/165 (21%), Positives = 80/165 (48%), Gaps = 17/165 (10%)
Query: 113 SQSETEVRQK-QQLQLMQSK---YKQKLKREESVRIKKEAEEAE-LQKMKA---IQREKS 164
S E E++ Q+L+ Q K + +L+ E+ +++E++ A+ L++++A QR +S
Sbjct: 2642 SSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQS 2701
Query: 165 NKL----EEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWA 220
++L + ++ ++NL++E EH + + + L E S Q + +S T
Sbjct: 2702 SRLCVALKHEQTAKDNLQKELRIEHSRCE-----ALLAQERSQLSELQKDLAAEKSRTLE 2756
Query: 221 RSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKI 265
S A R E + + HQ ++ Q+ ++E++++
Sbjct: 2757 LSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKSRV 2801
Score = 29.6 bits (65), Expect = 3.5
Identities = 43/223 (19%), Positives = 91/223 (40%), Gaps = 13/223 (5%)
Query: 82 RIAEQELANLEKWKEQNRAKP---VHLVPRRLGGSQSETEVRQKQQLQ-LMQSKYKQKLK 137
++ E++L +L++ + +A L +R S+ ++ +Q + +Q + + +
Sbjct: 2668 QLEEEQLRHLQRESQSAKALEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHS 2727
Query: 138 REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFRE------HQQYKTA 191
R E++ ++ ++ +ELQK A ++ ++ +L E R + L + + HQ +
Sbjct: 2728 RCEALLAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAH 2787
Query: 192 EFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELL 251
L + E R A+ S + L+AE + + ++ E+ + L
Sbjct: 2788 HALLQKLKEEKSRVVDLQAMLEKVQQQALHS---QQQLEAEAQKHCEALRREKEVSATLK 2844
Query: 252 ELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQSG 294
Q+R E R A+L +S P EQ G
Sbjct: 2845 STVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEG 2887
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 52.0 bits (123), Expect = 7e-07
Identities = 40/167 (23%), Positives = 88/167 (52%), Gaps = 19/167 (11%)
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
++Q+LQ ++ + +++ +RE+ ++ AEE + ++++ ++RE+ K EEK R +E +R+
Sbjct: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER--KREEKLRKREQKQRD 331
Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKM 240
Q K L KL E ++ Q + R L A+ N + ++
Sbjct: 332 RELRRNQKK----LEKLQAE--EQKQLQEKI----------KLEERKLLLAQRNLQSIRL 375
Query: 241 KDEQHQKSELLELKRQQQEQERAKI-HQTEHRRVNNAFLDRLQGKSQ 286
E +++ ++L+ Q+Q++E+ ++ Q E RR+ A L R++ + +
Sbjct: 376 IAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKE 422
Score = 51.6 bits (122), Expect = 9e-07
Identities = 46/205 (22%), Positives = 97/205 (47%), Gaps = 31/205 (15%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
+++ Q+L LE+ +E+ + + R+ + + E+ + ++ + K ++KL++ E
Sbjct: 271 RQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELER----ERKREEKLRKRE 326
Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKT-AEFLSKLNT 199
+ +E + +K++ +Q E+ +L+EK +L+E A R Q + AE LS+
Sbjct: 327 QKQRDRELRRNQ-KKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSR--- 382
Query: 200 ESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 259
A++ R+ + EE +LQ+ E+ ++ + EL+R ++E
Sbjct: 383 --------------------AKAVKLREQEQKEEKLRLQQQ--EERRRLQEAELRRVEEE 420
Query: 260 QERAKIHQTEHRRVNNAFLDRLQGK 284
+ERA Q + R + L L K
Sbjct: 421 KERALGLQRKERELRERLLSILLSK 445
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/173 (21%), Positives = 82/173 (47%), Gaps = 9/173 (5%)
Query: 92 EKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEA 151
EK +E+ R + R E E + ++Q + MQ + ++ ++EE K + +E
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE----KMQEQEE 638
Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
++ + + E+ K+ E++RL E ++E EH++ + E + + + ++ +
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPE--QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 212 CGPQSSTWARSWAYRDSLKAEENRKL---QKMKDEQHQKSELLELKRQQQEQE 261
+ TW + + E +K+ ++M EQ +K + E K Q+QE+E
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Score = 49.3 bits (116), Expect = 4e-06
Identities = 47/206 (22%), Positives = 91/206 (44%), Gaps = 19/206 (9%)
Query: 76 RRNEIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
R+ E R E+++ E+ W+++ R R G E E + +Q + ++ + K
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERL-------REQEGKMREQEEKMWRQEKRLREQEK 328
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQEN--LRREAFREHQQYKTA 191
+ ++E+ +R +KE E E Q + Q EK + EEK R QE R+E Q+ +
Sbjct: 329 ELREQEKELREQKELREQEEQMQE--QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 192 EFLSKLNT------ESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQH 245
E K+ E +R + Q W + R+ K +E K + ++E+
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Query: 246 QKSELLELKRQQQEQERAKIHQTEHR 271
Q+ E + + ++ +E + + E +
Sbjct: 447 QEEERIREREKKMREEEETMREQEEK 472
Score = 45.8 bits (107), Expect = 5e-05
Identities = 40/203 (19%), Positives = 89/203 (43%), Gaps = 29/203 (14%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
++I EQE +EK ++ K R S E E + +++ ++M+ + ++ ++EE
Sbjct: 684 EKIWEQE--KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL------ 194
K + +E E+ + + E+ K+ E++RL E ++E EH++ + E +
Sbjct: 742 ----KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE--QKEKLWEHEKMQEQEKIWEQEEK 795
Query: 195 ------------SKLNTESPDRSACQSAVCGPQSSTWARS---WAYRDSLKAEENRKLQK 239
K+ + + + G + W + W + + +E + +K
Sbjct: 796 MRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Query: 240 MKDEQHQKSELLELKRQQQEQER 262
M+ ++ + E E R Q+E+ R
Sbjct: 856 MQGQEEKMREQEEKMRGQEEKMR 878
Score = 42.0 bits (97), Expect = 7e-04
Identities = 44/229 (19%), Positives = 103/229 (44%), Gaps = 21/229 (9%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
+++ EQE + W+++ R R + E R +Q + ++ K +++++ +E
Sbjct: 362 EKMREQEE---KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK-EERMREQE 417
Query: 141 SV--RIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198
+ +++K EE ++Q+ + R++ K++E++R++E ++ E + E + K
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 477
Query: 199 T---ESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKR 255
E ++ Q + + W + K E +K++D++ + ++ R
Sbjct: 478 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE--EKIRDQEEMWGQEKKMWR 535
Query: 256 QQQ--EQERAKIHQTEHRRVNNAFL----DRLQGKSQPGGLEQSGGCWN 298
Q++ EQE Q E R + +R++ K+Q EQ W+
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ----EQEKKTWD 580
Score = 42.0 bits (97), Expect = 7e-04
Identities = 45/219 (20%), Positives = 105/219 (47%), Gaps = 29/219 (13%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK--- 133
R + Q++ +QE E+ E+ R K + + Q E ++R+++++Q + K +
Sbjct: 386 REQEQKMRDQEERMWEQ-DERLREKEERMREQEKMWEQVE-KMREEKKMQEQEKKTRDQE 443
Query: 134 QKLKREESVRIK----KEAEEAELQKMKAIQREKSN--KLEEKKRLQENLRREAFREHQQ 187
+K++ EE +R + +E EE ++ + +Q+++ N + EEK+ Q+ L + + +Q
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARS---------WAYRDSLKAEENR--- 235
K E K+ E ++ Q + G + W + W + ++ +E +
Sbjct: 504 EKMQEQEEKI-WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 236 ---KLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 271
+++K EQ +K+ + + + +E+ER + + + R
Sbjct: 563 QEERMEKKTQEQEKKT--WDQEEKMREEERMREREKKMR 599
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/192 (19%), Positives = 82/192 (42%), Gaps = 4/192 (2%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
+++ EQE E+ ++ + +RL + + +K Q Q + ++K+ +E
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTE 200
+ K + +E + + ++ E+S + EKK +E E RE Q+ K E K+ +
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE---EMMRE-QEEKMQEQEEKMQEQ 746
Query: 201 SPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQ 260
+ + + + W + K E+ K+Q+ + Q+ ++ + + + + Q
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 261 ERAKIHQTEHRR 272
E Q E R
Sbjct: 807 EEKMRGQEEKMR 818
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/165 (24%), Positives = 80/165 (48%), Gaps = 18/165 (10%)
Query: 116 ETEVRQKQQLQLMQSK---YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKR 172
+ E R +++ Q + K ++K++ EE +R ++E + E ++M Q EK + EEK +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMR-EREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 173 LQEN--LRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLK 230
QE +E + Q+ K E K+ E ++ Q + + W K
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKM-WEQEEKMWEQQRLPEQKEKLWEHE-------K 672
Query: 231 AEENRKLQKMKDEQHQKSELLELKRQQQEQ---ERAKIHQTEHRR 272
+E K+Q+ ++E+ + E +E K Q+QE+ ++ K+ + E R
Sbjct: 673 MQEQEKMQE-QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Score = 37.4 bits (85), Expect = 0.017
Identities = 28/148 (18%), Positives = 64/148 (43%), Gaps = 6/148 (4%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQE 175
E E + +Q + M+ + ++ +EE + K + +E + + RE+ E +K+++E
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 176 NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTW---ARSWAYRDSLKAE 232
E Q+ K E K+ + + + + W + W + + +
Sbjct: 601 ---EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 233 ENRKLQKMKDEQHQKSELLELKRQQQEQ 260
+ QK K +H+K + E ++Q+E+
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Score = 36.6 bits (83), Expect = 0.029
Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 23/189 (12%)
Query: 84 AEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVR 143
+E +L E ++ RAK L+P+ + E RQ+++L+ + K + K+EE +
Sbjct: 242 SEIQLNVKELKRKLERAK--FLLPQVQTNTLQEEMWRQEEELREQEKKIR---KQEEKMW 296
Query: 144 IKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPD 203
++E + KM+ Q EK + E++ R QE RE +E ++ K + E +
Sbjct: 297 RQEERLREQEGKMRE-QEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE 355
Query: 204 RSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERA 263
+ W + ++ +E + ++ + Q+ ++ E +++ ++QE
Sbjct: 356 KM-----------------WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Query: 264 KIHQTEHRR 272
Q E R
Sbjct: 399 MWEQDERLR 407
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 50.8 bits (120), Expect = 1e-06
Identities = 42/158 (26%), Positives = 82/158 (51%), Gaps = 12/158 (7%)
Query: 114 QSETEVRQKQQLQLMQSKYKQKLKREESVR-----IKKEAEEAELQKMK-AIQREKSNKL 167
+ E + ++Q ++ Q + ++KL EE+ R + K EE EL+K K I+RE ++
Sbjct: 103 EEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEE-ELEKRKDEIEREVLRRV 161
Query: 168 EEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRD 227
EE KR+ E ++ E ++ + AE ++ E +R+ + + + R A
Sbjct: 162 EEAKRIME---KQLLEELERQRQAELAAQKAREEEERAKREELERILEENN--RKIAEAQ 216
Query: 228 SLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKI 265
+ AEE ++ + + + H++ LE +RQ+Q++E KI
Sbjct: 217 AKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKI 254
Score = 33.5 bits (75), Expect = 0.24
Identities = 40/206 (19%), Positives = 86/206 (41%), Gaps = 19/206 (9%)
Query: 90 NLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE 149
N ++ + ++R++ V +R +S+ R++ + + + + + R +
Sbjct: 21 NKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPD 80
Query: 150 EAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQS 209
++ +R + L+EK++ +E ++ F ++ + E KL E R +
Sbjct: 81 RIDIFGRTVSKR---SSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEEL 137
Query: 210 AVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQ----------E 259
+ R +D ++ E R++++ K +K L EL+RQ+Q E
Sbjct: 138 VAKRVEEELEKR----KDEIEREVLRRVEEAKRIM-EKQLLEELERQRQAELAAQKAREE 192
Query: 260 QERAKIHQTEH-RRVNNAFLDRLQGK 284
+ERAK + E NN + Q K
Sbjct: 193 EERAKREELERILEENNRKIAEAQAK 218
Score = 31.2 bits (69), Expect = 1.2
Identities = 43/200 (21%), Positives = 82/200 (41%), Gaps = 16/200 (8%)
Query: 3 TRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQR 62
+R+R ++ S R P R +R L+ K E ++
Sbjct: 54 SRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQ 113
Query: 63 RTSAYTLIAPNINRRNEIQRI----AEQELANLEKWKEQNRAKPVHLVP--RRLGGSQSE 116
R I + +R+ A++ LEK K++ + + V +R+ Q
Sbjct: 114 RKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLL 173
Query: 117 TEVRQKQQLQLMQSKYKQ---KLKREESVRIKKEAEE--AELQKMKAIQR----EKSNKL 167
E+ +++Q +L K ++ + KREE RI +E AE Q A ++ E+ K+
Sbjct: 174 EELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKI 233
Query: 168 -EEKKRLQENLRREAFREHQ 186
EE+ +L++ +R+ E +
Sbjct: 234 HEERMKLEQERQRQQKEEQK 253
Score = 30.4 bits (67), Expect = 2.1
Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 30/173 (17%)
Query: 110 LGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE 169
+G S+S + R K SK+ +K R S KE R++S E
Sbjct: 1 MGRSRSRSSSRSKHT---KSSKHNKKRSRSRSRSRDKERV-----------RKRSKSRES 46
Query: 170 KKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSL 229
K+ N RRE+ + TA ++ DR S + + R+ + R SL
Sbjct: 47 KR----NRRRESRSRSRSTNTA-----VSRRERDRERASSP--PDRIDIFGRTVSKRSSL 95
Query: 230 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 282
++ R+ ++ K E ++ ++ +QQE E I + RRV R++
Sbjct: 96 DEKQKREEEEKKAEFERQRKI-----RQQEIEEKLIEEETARRVEELVAKRVE 143
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 50.1 bits (118), Expect = 3e-06
Identities = 40/176 (22%), Positives = 77/176 (43%), Gaps = 31/176 (17%)
Query: 109 RLGGSQSETEVRQKQQLQLMQSKYKQ----------KLKREESVRIKKEAEEAELQKMKA 158
RL Q E RQ++++Q + K ++ K++R+E + +KE + ++M
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 340
Query: 159 IQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSST 218
+ EK +LEEK QE +R + + ++ K E + E
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE------------------ 382
Query: 219 WARSWAYRDSLKAEEN--RKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 272
A+ W + ++ +E R+ ++M EQ +K E K +QE+E + + R+
Sbjct: 383 -AKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Score = 47.4 bits (111), Expect = 2e-05
Identities = 43/201 (21%), Positives = 91/201 (45%), Gaps = 7/201 (3%)
Query: 74 INRRNEIQRIAEQELANLE-KWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKY 132
+ R+ E+ E+++ LE K EQ + + R+ E E RQ+Q+ ++ + +
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQE-EKRQEEEKIREQEKRQEQEAKMWRQEE 390
Query: 133 KQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192
K + ++EE +R ++E + + +KM + + + EE + +E +RR+ + +Q K
Sbjct: 391 KIR-EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 193 FLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQ----HQKS 248
+ E + Q G Q A + + R+ +K+++++ Q+
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Query: 249 ELLELKRQQQEQERAKIHQTE 269
++ E + QEQE Q E
Sbjct: 510 KIREQEEMMQEQEEKMWEQEE 530
Score = 36.2 bits (82), Expect = 0.037
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ-- 134
R + ++I EQE E+ ++ + Q E RQ+++++ + K ++
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 135 -KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEK-KRLQENLRREAFREHQQ 187
K++ +E + ++E + E ++ Q EK + EEK +R +E +R + R QQ
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Score = 32.3 bits (72), Expect = 0.54
Identities = 23/99 (23%), Positives = 56/99 (56%), Gaps = 4/99 (4%)
Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141
++ EQE A +++ +E+ R + + + + E ++R+++ ++MQ + ++ ++EE
Sbjct: 475 KMCEQE-AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE--EMMQEQEEKMWEQEEK 531
Query: 142 VRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
+ ++E + + +KM+ Q EK + E + R QE +E
Sbjct: 532 MCEQEEKMQEQEEKMRR-QEEKMREQEVRLRQQEEKMQE 569
Score = 28.5 bits (62), Expect = 7.8
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 11/153 (7%)
Query: 122 KQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQ---REKSNKLEEKKRLQENLR 178
+Q L + ++ K+ + E + +++A EL + +EK+ KL+EK +L E+ +
Sbjct: 166 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 225
Query: 179 REAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQ 238
E ++ K +KL A + S A+ A + EEN
Sbjct: 226 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA-----QVEENELWN 280
Query: 239 KMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 271
++ +Q +K E K Q++E+ KI + E +
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREE---KIQEQEEK 310
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 49.7 bits (117), Expect = 3e-06
Identities = 52/217 (23%), Positives = 98/217 (45%), Gaps = 16/217 (7%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
+++ +E+++A L+K E+ A+ + ++L + E + + K L+ QS+Y K+ +E
Sbjct: 470 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEY-LKISQE 528
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNT 199
+ + EE ELQK KAI E NKL + ++ E R + + L +
Sbjct: 529 KEQQESLALEELELQK-KAILTESENKLRDLQQEAETYRTRILELESSLEKS--LQENKN 585
Query: 200 ESPDRSACQSAVCGPQSSTWA----RSWAYRDSLKAEEN----RKLQKMKDEQHQKSELL 251
+S D + A + + +SLK +++ KLQ +K + + E L
Sbjct: 586 QSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKL 645
Query: 252 ELKRQQQEQERAK----IHQTEHRRVNNAFLDRLQGK 284
K +Q+++ K I Q +N L++L K
Sbjct: 646 REKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/203 (23%), Positives = 86/203 (42%), Gaps = 15/203 (7%)
Query: 82 RIAEQELA---NLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKR 138
RI E E + +L++ K Q++ VHL + ++ T + +K + +L K++Q
Sbjct: 568 RILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALW 627
Query: 139 EESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198
E +++ K+ + E++K+ REK + +E + + +A E KT E L
Sbjct: 628 TEKLQVLKQQYQTEMEKL----REKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQ 683
Query: 199 TESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQ 258
TE S+ S V + +D + KMK E K + + QQQ
Sbjct: 684 TELESLSSELSEVLKARHKLEEELSVLKD--------QTDKMKQELEAKMDEQKNHHQQQ 735
Query: 259 EQERAKIHQTEHRRVNNAFLDRL 281
K H+ +R A D++
Sbjct: 736 VDSIIKEHEVSIQRTEKALKDQI 758
Score = 41.2 bits (95), Expect = 0.001
Identities = 61/276 (22%), Positives = 117/276 (42%), Gaps = 46/276 (16%)
Query: 33 ELSPVEDQREGLEAAPKGPSRESVVHAGQRRT---SAYTLIAPNINRRNEIQRI-AEQEL 88
E+ + + E L+A + R + T S L+ P + E Q E +L
Sbjct: 1873 EMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKL 1932
Query: 89 ANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEA 148
A E+ K Q K + + + L + E +Q+L++++ +Y Q+ REE +IK+E
Sbjct: 1933 AGAEREK-QKLGKEIVRLQKDLRMLRKE----HQQELEILKKEYDQE--REE--KIKQEQ 1983
Query: 149 EEAELQK---MKAIQREKSNKLEEKKRLQENLRREAFREHQ----------QYKTAEFLS 195
E+ EL+ +K + RE + +L +K++ E +E + Q Q +T + L
Sbjct: 1984 EDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLK 2043
Query: 196 KLNTESPD---------------RSACQSAVCGPQSSTWARSWAYRDSLKAEENR----- 235
K+ + D + V Q+ Y+ L+ EEN
Sbjct: 2044 KIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNV 2103
Query: 236 KLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 271
+ +++ + QK+ L+ + ++++ R +IH E R
Sbjct: 2104 TIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDR 2139
Score = 40.8 bits (94), Expect = 0.002
Identities = 45/208 (21%), Positives = 102/208 (49%), Gaps = 20/208 (9%)
Query: 68 TLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGG---SQSETEVRQKQQ 124
TL +++ ++++ E L + ++Q AK + + G + S E QK+Q
Sbjct: 969 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQ 1028
Query: 125 LQLMQSKYKQKLKREESVRIKKEAEEA-ELQKMKAIQ-REKSNKLEEKKRL-------QE 175
++ + ++++L S+ KK ++A ELQ++ IQ +EK ++ E K+ +E
Sbjct: 1029 IESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1088
Query: 176 NLRRE-AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEEN 234
+ +E + + + K L++L + +SA +++ ++ + A+ + L+ + N
Sbjct: 1089 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDET----KLKAHLEKLEVDLN 1144
Query: 235 RKLQKMKDEQHQKSELLELKRQQQEQER 262
+ L K+ + +L+ELK +E +R
Sbjct: 1145 KSL---KENTFLQEQLVELKMLAEEDKR 1169
Score = 39.7 bits (91), Expect = 0.003
Identities = 62/286 (21%), Positives = 125/286 (43%), Gaps = 50/286 (17%)
Query: 31 QGELSPVEDQREGLEAAPKGPSR---ESVVHAGQRRTSAYTL--IAPNINRRNEIQ-RIA 84
+ + S +E + LE K + E H Q+ +L + N N++ +I+ +
Sbjct: 1503 EDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKEL 1562
Query: 85 EQELANLEKWKEQ--NRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESV 142
Q+L + ++ E+ NR K E + + Q+ M+++ + K K E V
Sbjct: 1563 VQKLQHFQELGEEKDNRVKEAE-----------EKILTLENQVYSMKAELETKKKELEHV 1611
Query: 143 RIKKEAEEAELQKMK-AIQREKSNKLEEKKR--------LQENLRREAFREHQQYK--TA 191
+ +++E EL+ ++ ++ E + KL E KR +++ L + + +QYK T
Sbjct: 1612 NLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTE 1671
Query: 192 EFLSKLNTESPDR---------------SACQSAVCGPQSSTWARSWAYRDSLKAEENRK 236
LS+LNT+ +R S+ + P+S+ AY + +A+
Sbjct: 1672 SHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSA--KNVAAYTEQEEADSQGC 1729
Query: 237 LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 282
+QK +E K +L+ ++E+ ++ Q + V++ F R Q
Sbjct: 1730 VQKTYEE---KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQ 1772
Score = 30.0 bits (66), Expect = 2.7
Identities = 52/301 (17%), Positives = 122/301 (40%), Gaps = 65/301 (21%)
Query: 30 RQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYT--LIAPNINRRNEIQRIAEQE 87
++ EL +ED+ E AA + +++ +A L++ + + ++ E
Sbjct: 1618 KEEELKALEDRLESESAAKLAELKRKA----EQKIAAIKKQLLSQMEEKEEQYKKGTESH 1673
Query: 88 LANLEKWKEQNRAKPVHLVPRRLGG---SQSETEV------------------------- 119
L+ L K Q R + VH++ +L SQSET +
Sbjct: 1674 LSELNT-KLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQK 1732
Query: 120 RQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRR 179
++++ ++Q +K K + V +KE + +M+ +E+ KLE
Sbjct: 1733 TYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEH---------- 1782
Query: 180 EAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRK--- 236
E +Q++ + L E +++ S + +++++A++N +
Sbjct: 1783 ---AEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQH----VEKEGGKNNIQAKQNLENVF 1835
Query: 237 --LQKMKDEQHQKSELLELKRQQQEQ---ERAKIHQTEHRRVNNAF-----LDRLQGKSQ 286
+QK E+ ++LE K ++ + + ++H+ E + + + L ++ G+++
Sbjct: 1836 DDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNK 1895
Query: 287 P 287
P
Sbjct: 1896 P 1896
Score = 28.9 bits (63), Expect = 6.0
Identities = 45/219 (20%), Positives = 97/219 (44%), Gaps = 34/219 (15%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL-MQSKYKQK 135
R+ I+++ Q L + KE++ + + L +Q E R+K + ++ Q K +K
Sbjct: 388 RSRIKQMTTQG-EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 136 LKREESVRI---------------KKEAEE--AELQKM--KAIQREKSNKLEEKKRLQEN 176
EE + + KK +EE A+LQK+ K + R K +L +K + +E
Sbjct: 447 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQTRER 505
Query: 177 LRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRK 236
+E + + +E+L K++ E + +S + ++ E K
Sbjct: 506 EFQEQMKVALEKSQSEYL-KISQEKEQQ----------ESLALEELELQKKAILTESENK 554
Query: 237 LQKMKDE-QHQKSELLELKRQQQEQERAKIHQTEHRRVN 274
L+ ++ E + ++ +LEL+ ++ + +Q++ V+
Sbjct: 555 LRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVH 593
Score = 28.5 bits (62), Expect = 7.8
Identities = 37/170 (21%), Positives = 72/170 (42%), Gaps = 18/170 (10%)
Query: 37 VEDQREGLE----AAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRI---AEQELA 89
++ ++E LE + K RE Q+ I IN+ E++ + QE
Sbjct: 1979 IKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEET 2038
Query: 90 N--LEKW--KEQNRAKPVHLVPRRLGGSQSE--TEVRQKQ-QLQLMQSKYKQKLKREESV 142
N L+K K+ + + L + E +VR Q QL+ +Q KY+QKL++EE+
Sbjct: 2039 NQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN- 2097
Query: 143 RIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192
+ + +++ +K+ + + K ++ R + + K E
Sbjct: 2098 ---PGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYE 2144
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 49.3 bits (116), Expect = 4e-06
Identities = 43/204 (21%), Positives = 92/204 (45%), Gaps = 31/204 (15%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135
R+ E ++ ++E EK K + R + +R + E R+K++ + + K+K
Sbjct: 46 RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER----RKRKKEK 101
Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLS 195
KRE R ++E ++ + +K + + ++ + + KKR ++ R+E RE ++ K
Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161
Query: 196 KLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLE--L 253
K E ++ K E NRK +K + E+ ++ E +
Sbjct: 162 KRKKEEREK-------------------------KRERNRKERKKERERKERRERKKERK 196
Query: 254 KRQQQEQERAKIHQTEHRRVNNAF 277
K +++++ER K +T+ + + F
Sbjct: 197 KERRKKKERKKDRKTDRQTDSQVF 220
Score = 45.1 bits (105), Expect = 8e-05
Identities = 38/159 (23%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 114 QSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRL 173
+ E R+K++ + + + +++ K+E+ R K+E + +K K +REK K +K
Sbjct: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK--EREKQRKERREKER 94
Query: 174 QENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEE 233
++ + + RE +Q E K + +R Q + R R K E+
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRR---ERKRKKRRKKKRRKERKREK 151
Query: 234 NRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 272
R ++ K ++ +K E E KR++ +ER K + + RR
Sbjct: 152 ERGKRERKRKKRKKEE-REKKRERNRKERKKERERKERR 189
Score = 42.4 bits (98), Expect = 5e-04
Identities = 37/170 (21%), Positives = 78/170 (45%), Gaps = 10/170 (5%)
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
Q++ + + + ++K KRE K+E + E +K K +RE+ + E K++ +E R+E
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRK--KRERGKERERKRKEREKQRKE 88
Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKM 240
RE ++ K + K + R + + R R K ++ RK ++
Sbjct: 89 R-REKERRKRKKEKKKRERKQRGRRERKKK---KERKERERENKQRRERKRKKRRKKKRR 144
Query: 241 KDEQHQKS----ELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQ 286
K+ + +K E KR+++E+E+ + + R+ +R + K +
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Score = 37.4 bits (85), Expect = 0.017
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 5/160 (3%)
Query: 115 SETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE-KKRL 173
S V+ +LQ++ + K + KKE E E +K +REK K E KK
Sbjct: 7 SRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKR---EREKERKRERGKKEK 63
Query: 174 QENLRREAFREHQ-QYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAE 232
++ +RE +E + + K E K E R + + R + K
Sbjct: 64 KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
Query: 233 ENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 272
E Q+ + ++ ++ + K +++E+ER K + +R
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR 163
Score = 31.6 bits (70), Expect = 0.92
Identities = 22/129 (17%), Positives = 57/129 (44%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135
++ E ++ +E ++ KE+ R +R + + +K++ + + + K+K
Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161
Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLS 195
+++E K+E E +K + + + K E KK ++ R+ R+ + ++
Sbjct: 162 KRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221
Query: 196 KLNTESPDR 204
L + +R
Sbjct: 222 PLRESAFNR 230
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 48.9 bits (115), Expect = 6e-06
Identities = 49/209 (23%), Positives = 95/209 (45%), Gaps = 14/209 (6%)
Query: 77 RNEIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGS-QSETEVRQKQQLQLMQSK-- 131
+ E R EQ++ + E+ W++ R + R Q E ++R++++ Q + K
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Query: 132 -YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQEN--LRREAFREHQQY 188
++K++ EE +R ++E + E ++M Q EK + EEK R QE +E + Q+
Sbjct: 551 DQEEKMREEERMR-EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 189 KTAEFLSKL-NTESPDRSACQSAVCGPQSSTW----ARSWAYRDSLKAEENRKLQKMKDE 243
K E K+ E D+ Q + Q + W + ++ +E + ++ +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 244 QHQKSELLELKRQQQEQERAKIHQTEHRR 272
Q Q+ ++ E + + Q QE Q E R
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/227 (19%), Positives = 106/227 (46%), Gaps = 26/227 (11%)
Query: 68 TLIAPNINRRN-EIQ---RIAEQELANLE---KWKEQNRAKPVHLVPRRLGGSQSETEVR 120
T+ + ++N E+Q R+AE E + ++ K ++ + L+P+ + E R
Sbjct: 179 TITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR 238
Query: 121 QKQQLQLMQSKYKQK----LKREESVR----------IKKEAEEAELQKMKAIQREKSNK 166
Q+++L+ + K +++ ++EE +R K +E L++ + RE+ +
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 167 LEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYR 226
L E+K+L+E +E + Q+ K E K+ + + + + + R
Sbjct: 299 LREQKKLRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 227 DSLKA--EENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 271
D + E++ +L++ ++ ++ ++ E + + QE+ER + + + R
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402
Score = 38.5 bits (88), Expect = 0.008
Identities = 39/222 (17%), Positives = 96/222 (43%), Gaps = 38/222 (17%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQKLKRE 139
QR+ EQ+ E+ K Q + + + + E ++R ++++ + K ++Q+ RE
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIW---------EQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 140 ESVRIKKEAEEAELQKMKAI--------QREKSNKLEEKKRLQ-------ENLRREAFRE 184
+ ++ ++ E+ Q+ K Q E+ + EE+ R Q E +R E +
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 185 HQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQ 244
Q+ KT + K+ E R + + + E+ K+Q+ +++
Sbjct: 544 EQEKKTWDQEEKMREEERMRER-------------EKKMREEEEMMREQEEKMQEQEEKM 590
Query: 245 HQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQ 286
++ E + + ++ +++ K+ + E + D++Q + +
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Score = 37.7 bits (86), Expect = 0.013
Identities = 40/208 (19%), Positives = 88/208 (42%), Gaps = 17/208 (8%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R + +R+ EQE E+ KE K + R E E + +Q + M+ + ++
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKL----REQEEQMQEQEEKMWEQEEKMREQEEKMW 334
Query: 137 KREESVRIKKEAEEAELQKMKAI------QREKSNKLEEKKRLQENLRREAFREHQQYKT 190
++EE + +++ + QKM+ Q E+ + EE+ R QE + + + ++ +
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 191 AEFLSKLNTESPDRSACQSAVCGPQSSTWA---RSWAYR----DSLKAEENRKLQKMKDE 243
E K+ E + + + + W + W + K E K+Q+ +++
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 244 QHQKSELLELKRQQQEQERAKIHQTEHR 271
++ E + + + QE+ Q + R
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
Score = 37.4 bits (85), Expect = 0.017
Identities = 39/206 (18%), Positives = 94/206 (45%), Gaps = 17/206 (8%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R + +++ EQE + W+++ + + R E E + ++Q Q M+ + ++
Sbjct: 306 REQEEQMQEQEE---KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
Query: 137 KREESVRIKKEA---------EEAELQKMKAIQREKSNKL---EEKKRLQENLRREAFRE 184
+++E +R K+E +E ++Q+ + I RE+ K+ EE R QE ++
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQEEN 421
Query: 185 HQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKA-EENRKLQKMKDE 243
+ + E+ + E ++ Q + + W + RD + + +K+ + +
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 244 QHQKSELLELKRQQQEQERAKIHQTE 269
+ Q+ ++ E + + ++QE+ Q E
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEE 507
Score = 36.2 bits (82), Expect = 0.037
Identities = 37/174 (21%), Positives = 78/174 (44%), Gaps = 9/174 (5%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R E + + EQE +++ +E+ R + + + + E ++ ++++ Q + +
Sbjct: 570 REEEEMMREQE-EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 137 KREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENL---RREAFREHQQYKTAEF 193
++EE + ++E + + +KM Q EK + EEK R QE + E RE Q+ K
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWE-QEEKMREQEEKMREQEEKMQGQEEKMRE-QEEKMQGQ 686
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWA---RSWAYRDSLKAEENRKLQKMKDEQ 244
K+ + + + G + W + W + + EE + QK K ++
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740
Score = 32.7 bits (73), Expect = 0.41
Identities = 24/112 (21%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
+++ EQE + W+++ + + R E + ++Q + MQ + ++ ++EE
Sbjct: 639 EKMQEQEE---KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 141 SVRIKKEAEEAELQKM-----KAIQREKSNKLEEKKRLQENLRREAFREHQQ 187
+R ++E + +KM K +E+ + EE+ R Q+ +E EH++
Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 31.2 bits (69), Expect = 1.2
Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQE 175
E E + ++Q + MQ + ++ ++EE ++ ++E + +KM+ Q EK EEK QE
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG-QEEKMWGQEEKMWGQE 715
Query: 176 NLR--REAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQS 216
+E RE ++ + + K+ P+ S C P S
Sbjct: 716 EKMWGQEEMREKEE-RIRDQKEKMQERLPEHEERCSEPCLPPS 757
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 48.9 bits (115), Expect = 6e-06
Identities = 44/217 (20%), Positives = 102/217 (47%), Gaps = 35/217 (16%)
Query: 24 PQDPSGRQGELSPVE----DQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNE 79
PQ P G QG L P + Q+ P+GP R+ ++ T + L +P + ++ +
Sbjct: 3792 PQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLM------TQSRVLSSPQLAQQGQ 3845
Query: 80 IQR-----IAEQELANLEKWKEQNRAKPVHLVPRRLGGS----------------QSETE 118
A+Q+ + ++ + A HL + S Q + +
Sbjct: 3846 GLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQ 3905
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178
++Q+QQLQ Q +Q+L++++ ++ ++ ++ + Q+++ Q+++ + +++ + Q+ +
Sbjct: 3906 LQQQQQLQQQQ---QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ 3962
Query: 179 REAFREHQQYKTAEFLSKLNT-ESPDRSACQSAVCGP 214
++ F++ QQ + L++ T SP + Q GP
Sbjct: 3963 QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP 3999
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.5 bits (114), Expect = 7e-06
Identities = 41/181 (22%), Positives = 86/181 (47%), Gaps = 10/181 (5%)
Query: 94 WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK-LKREESVRIKKEAEEAE 152
W+ + R + + R+ G + E+E +++++ + + + ++K KRE + KK + E
Sbjct: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
Query: 153 LQKMKAIQREKSNKL-EEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
++ K +REK NK EEK++ ++ ++E R ++ K E E R +
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE-----RKEERKREERKERE 148
Query: 212 CGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 271
+ R R K E +++ + ++E+ +K KR++ +ER K + + R
Sbjct: 149 RKKEEREKERE---RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
Query: 272 R 272
R
Sbjct: 206 R 206
Score = 42.7 bits (99), Expect = 4e-04
Identities = 42/236 (17%), Positives = 94/236 (39%), Gaps = 18/236 (7%)
Query: 27 PSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQ 86
P + G S + ++ +E +G +RR R+ E ++
Sbjct: 28 PCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRER---GKK 84
Query: 87 ELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKK 146
E K +E+ R K + G + + + ++K++ + K++ ++EE R ++
Sbjct: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
Query: 147 EAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSA 206
+ E + ++ + + K K E+K++ E +E ++ K E K + +R
Sbjct: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
Query: 207 CQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQER 262
+ + K +E RK ++ KD Q E KR+++E+++
Sbjct: 205 RRER---------------KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 48.5 bits (114), Expect = 7e-06
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 4/158 (2%)
Query: 112 GSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK 171
G E E + +Q + MQ + +Q ++EE +R K+E + E ++ Q E+ K EE+
Sbjct: 199 GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR-KQEEQMGEQEEQVQKQEEQVQKQEEQM 257
Query: 172 RLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKA 231
R QE RE + ++ + K TE +++ Q Q + ++
Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ---EEQMRE 314
Query: 232 EENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 269
+E + ++ + Q+ ++ E K Q EQ+ Q E
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Score = 47.8 bits (112), Expect = 1e-05
Identities = 52/249 (20%), Positives = 114/249 (45%), Gaps = 19/249 (7%)
Query: 30 RQGELSPVEDQ---REGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQ 86
++G++ E Q +EG +G RE GQ R + + +++ EQ
Sbjct: 155 QEGQVREQEGQVREQEGQVREQEGQVREQ---EGQVREQEGQMGEQEGQMGEQEEQMGEQ 211
Query: 87 ELANLEKWKEQ--NRAKPVHLVPRRLGGSQSETEVRQKQ-QLQLMQSKYKQKLKREESVR 143
E ++K +EQ + + + ++G + + + +++Q Q Q Q + +++ RE+ +
Sbjct: 212 E-EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 144 IKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPD 203
++++ E+ QK + Q E++ + EE+ R QE RE +E Q + E + E +
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE--QEEQMREQEEQMR----EQEE 324
Query: 204 RSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERA 263
+ Q Q + W ++ + +E + ++ + Q Q+ ++ + + Q ++QE
Sbjct: 325 QMGKQEEQMWEQKE---QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
Query: 264 KIHQTEHRR 272
Q E R
Sbjct: 382 MRKQEEQMR 390
Score = 39.3 bits (90), Expect = 0.004
Identities = 38/197 (19%), Positives = 89/197 (45%), Gaps = 16/197 (8%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+ ++ E R E+++ E EQ R + ++ ++ Q+E E + +Q + M+ + +
Sbjct: 250 VQKQEEQMRKQEEQMREQE---EQMREQEEQMLKQK---EQTEQEEQTGEQEEQMREQEE 303
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEF 193
Q ++EE +R E EE ++ + + +++ E+K+++ E + +E Q + E
Sbjct: 304 QMREQEEQMR---EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLEL 253
+ K ++ Q Q + + ++ +E + ++ + QK ++ E
Sbjct: 361 MQK----QEEQVRKQEEQMRKQEEQMRKQ---EEQMRKQEEQMGEQKEQMGEQKEQMREQ 413
Query: 254 KRQQQEQERAKIHQTEH 270
+ Q EQ+ Q EH
Sbjct: 414 EEQMGEQKEQMRKQEEH 430
Score = 32.7 bits (73), Expect = 0.41
Identities = 26/128 (20%), Positives = 65/128 (50%), Gaps = 8/128 (6%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL----QLMQSKY 132
R + +++ EQE E+ ++ + + + Q E +Q++Q+ + MQ +
Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365
Query: 133 KQKLKREESVRIKKEA---EEAELQKMKAIQREKSNKL-EEKKRLQENLRREAFREHQQY 188
+Q K+EE +R ++E +E +++K + E+ ++ E+K++++E + ++ Q
Sbjct: 366 EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425
Query: 189 KTAEFLSK 196
K E + +
Sbjct: 426 KQEEHMGE 433
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 48.5 bits (114), Expect = 7e-06
Identities = 52/239 (21%), Positives = 106/239 (44%), Gaps = 31/239 (12%)
Query: 27 PSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQ 86
P +Q +L D RE L+ A K +SV + T T +N + ++ +
Sbjct: 528 PVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVT----KVNHVEKPPKVESK 583
Query: 87 ELANLEKWKE-QNRAKPVHL---VPRRLGGSQSETEVRQKQQLQLMQSKYKQK-LKREES 141
E ++K K + KP VP + S + EV +KQ + K+K +K+E
Sbjct: 584 EKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETK 643
Query: 142 VRIKKEAEEAELQKMKAIQREKSNKLE-EKKRLQENLRREAFREHQQYKTAEFLSKLNTE 200
V+ + + EE E K + ++E ++ E+K +E +++E +E ++ + E ++ E
Sbjct: 644 VKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKE 703
Query: 201 SPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 259
+P + + +K EE ++++ K+E+ K E+ +L + ++
Sbjct: 704 TPPKEV-------------------KKEVKKEEKKEVK--KEEKEPKKEIKKLPKDAKK 741
Score = 32.3 bits (72), Expect = 0.54
Identities = 30/147 (20%), Positives = 66/147 (44%), Gaps = 2/147 (1%)
Query: 95 KEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQ 154
K++ + KP + + + K ++ + K+++K+E IKKE ++ +
Sbjct: 639 KKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKK 698
Query: 155 KMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGP 214
++K K K E KK ++ +++E ++ K +K + +P A + A P
Sbjct: 699 EVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAK-KSSTPLSEAKKPAALKP 757
Query: 215 QSSTWARSWAYRDSLKAEENRKLQKMK 241
+ S +DS+ A + ++ K+K
Sbjct: 758 KVPKKEES-VKKDSVAAGKPKEKGKIK 783
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/220 (21%), Positives = 107/220 (48%), Gaps = 32/220 (14%)
Query: 69 LIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLM 128
+++ ++ + +Q+ E A L++ ++ +A L+ + ++++ +V + +QL+
Sbjct: 1796 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQ 1855
Query: 129 ---QSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSN--KLEEKKRLQENLRREAFR 183
QS KL+ E +K E L++MK++ +E+ N ++EE +L+ + +E+ +
Sbjct: 1856 IKDQSLTLSKLEIENLNLAQKLHEN--LEEMKSVMKERDNLRRVEETLKLERDQLKESLQ 1913
Query: 184 E--------HQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLKAEENR 235
E Q+ KTA LSK + E+ D+ R +++ + +
Sbjct: 1914 ETKARDLEIQQELKTARMLSKEHKETVDK---------------LREKISEKTIQISDIQ 1958
Query: 236 K-LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVN 274
K L K KDE +K + L+ K Q + + ++ + H+++N
Sbjct: 1959 KDLDKSKDELQKKIQELQKKELQLLRVKEDVNMS-HKKIN 1997
Score = 35.4 bits (80), Expect = 0.064
Identities = 44/179 (24%), Positives = 72/179 (40%), Gaps = 44/179 (24%)
Query: 109 RLGGSQSETEVRQKQ-QLQLMQSKYKQKLK----REESVRIK------------KEAEEA 151
R+ S+ ETE+ Q QL+ + K + K++ +EE IK K+ +E
Sbjct: 1497 RVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEH 1556
Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
K A+Q +S LE RLQE + E + + E + Q A+
Sbjct: 1557 RKAKDSALQSIESKMLELTNRLQE--------------SQEEIQIMIKEKEEMKRVQEAL 1602
Query: 212 CGPQSSTWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEH 270
RD LK + KMK+ Q ++ + L++ + QE K+ + EH
Sbjct: 1603 -----------QIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE--KMCEIEH 1648
Score = 32.3 bits (72), Expect = 0.54
Identities = 45/221 (20%), Positives = 95/221 (42%), Gaps = 22/221 (9%)
Query: 79 EIQRIAEQELANLEKWKEQ--NRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKY---- 132
E R ++ L +E+ KEQ NR + V R +T + +K Q L + K
Sbjct: 877 EKTREVQERLNEMEQLKEQLENRDSTLQTVERE------KTLITEKLQQTLEEVKTLTQE 930
Query: 133 KQKLKR-EESVRIKKEAEEAELQKMKAI----QREKSNKLEEKKRLQENLRREAFREHQQ 187
K LK+ +ES++I+++ ++++ + Q + N LE K+ QE + + ++
Sbjct: 931 KDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEE 990
Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWA-----YRDSLKAEENRKLQKMKD 242
+ + E+ D + + A++ +D+ E+ RK+ +
Sbjct: 991 VSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQ 1050
Query: 243 EQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQG 283
E+++ ++LE ++EQ + + + + N RL G
Sbjct: 1051 EKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLG 1091
Score = 31.2 bits (69), Expect = 1.2
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 27/151 (17%)
Query: 54 ESVV-HAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPR---- 108
ESV+ Q +T I I + E++ + ++ L+K +E + H + +
Sbjct: 1060 ESVIAEKEQLKTDLKENIEMTIENQEELRLLGDE----LKKQQEIVAQEKNHAIKKEGEL 1115
Query: 109 -RLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKL 167
R +E E + K++ Q +Q K +Q L +E E +E+QK K N++
Sbjct: 1116 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQE--------EMSEMQK-------KINEI 1160
Query: 168 EEKKRLQENLRREAFREHQQYKTAEFLSKLN 198
E K +N +E EH + + E KLN
Sbjct: 1161 ENLKNELKN--KELTLEHMETERLELAQKLN 1189
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 47.8 bits (112), Expect = 1e-05
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 1/172 (0%)
Query: 112 GSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK 171
G Q + EV Q L L+ + +++L+ +E ++E E ++ Q E+ + EE+
Sbjct: 177 GRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERL 236
Query: 172 RLQEN-LRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWARSWAYRDSLK 230
R QE LR + R H+Q + + E +R Q + G + +
Sbjct: 237 REQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERR 296
Query: 231 AEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 282
EE +L + + + ELLE +R +Q+ ER +T L+RL+
Sbjct: 297 QEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLRELERLR 348
Score = 33.1 bits (74), Expect = 0.32
Identities = 47/218 (21%), Positives = 89/218 (40%), Gaps = 24/218 (11%)
Query: 65 SAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQ 124
S Y +A ++ + I + + +L + ++ + +HLV ++LG S + + + +
Sbjct: 89 SQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLV-QKLGRSLFKLKNQTAEP 147
Query: 125 L-----------QLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRL 173
L + +Q + K ESV + +AE Q + + R + +L E+
Sbjct: 148 LAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQ--- 204
Query: 174 QENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTW----ARSWAYRDSL 229
+E L + R H+Q + + E +R Q Q R + L
Sbjct: 205 EERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERL 264
Query: 230 KAEENR-----KLQKMKDEQHQKSELLELKRQQQEQER 262
+E R KL + + +LLE +R+Q+EQER
Sbjct: 265 CEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQER 302
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 47.8 bits (112), Expect = 1e-05
Identities = 59/250 (23%), Positives = 102/250 (40%), Gaps = 20/250 (8%)
Query: 40 QREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNR 99
QR E K P + Q R I +R E E E + E+ +E+N
Sbjct: 276 QRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDE-TEYEYSGSEEEEEEND 334
Query: 100 AKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAI 159
+ + G S T R +LQL + + L+R++ + ++E EE + Q +
Sbjct: 335 SGEPSSILNLPGES---TLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAER 391
Query: 160 QREKSNKLEEKKRLQENLRREAFREHQQYK--TAEFLSKLNTESPDRSACQSAVCGPQSS 217
Q+ + E+++RL+E RRE QQ + + ++ E R A
Sbjct: 392 QKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRA----------- 440
Query: 218 TWARSWAYRDSLKAEENRKLQKMKDE-QHQKSELLELKRQQQEQERAKIHQTEHRRVNNA 276
Y EE R+L+ ++ + H+++ LLE KR+Q E++R +
Sbjct: 441 --EHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERD 498
Query: 277 FLDRLQGKSQ 286
+L LQ + Q
Sbjct: 499 YLVSLQHQRQ 508
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.124 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,098,203
Number of Sequences: 37866
Number of extensions: 566843
Number of successful extensions: 10026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 285
Number of HSP's successfully gapped in prelim test: 749
Number of HSP's that attempted gapping in prelim test: 4918
Number of HSP's gapped (non-prelim): 3508
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.