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Search of human proteins with 151301053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151301053 RNA binding motif protein 33 [Homo sapiens]
(1170 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 2423 0.0
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 160 9e-39
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 115 2e-25
gi|160707881 formin 2 [Homo sapiens] 113 9e-25
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 108 3e-23
gi|47132519 Ras association and pleckstrin homology domains 1 is... 108 4e-23
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 105 2e-22
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 105 2e-22
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 104 4e-22
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 104 4e-22
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 104 4e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni... 101 4e-21
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 99 2e-20
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 98 4e-20
gi|150170670 piccolo isoform 2 [Homo sapiens] 98 4e-20
gi|150378539 piccolo isoform 1 [Homo sapiens] 98 4e-20
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 96 2e-19
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 96 2e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 96 3e-19
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 96 3e-19
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 96 3e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 96 3e-19
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 95 4e-19
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 95 4e-19
gi|210032580 SET domain containing 1B [Homo sapiens] 94 8e-19
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 93 1e-18
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 93 1e-18
gi|110349719 titin isoform N2-A [Homo sapiens] 93 2e-18
gi|55750053 atrophin-1 [Homo sapiens] 91 5e-18
gi|55750041 atrophin-1 [Homo sapiens] 91 5e-18
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 2423 bits (6279), Expect = 0.0
Identities = 1170/1170 (100%), Positives = 1170/1170 (100%)
Query: 1 MAAALGASGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQS 60
MAAALGASGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQS
Sbjct: 1 MAAALGASGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQS 60
Query: 61 DLSDEELNDDLLQSDNEDEENFSSQGVTISLNATSGMVTSFELSDNTNDQSGEQESEYEQ 120
DLSDEELNDDLLQSDNEDEENFSSQGVTISLNATSGMVTSFELSDNTNDQSGEQESEYEQ
Sbjct: 61 DLSDEELNDDLLQSDNEDEENFSSQGVTISLNATSGMVTSFELSDNTNDQSGEQESEYEQ 120
Query: 121 EQGEDELVYHKSDGSELYTQEYPEEGQYEGHEAELTEDQIEYVEEPEEEQLYTDEVLDIE 180
EQGEDELVYHKSDGSELYTQEYPEEGQYEGHEAELTEDQIEYVEEPEEEQLYTDEVLDIE
Sbjct: 121 EQGEDELVYHKSDGSELYTQEYPEEGQYEGHEAELTEDQIEYVEEPEEEQLYTDEVLDIE 180
Query: 181 INEPLDEFTGGMETLELQKDIKEESDEEEEDDEESGRLRFKTERKEGTIIRLSDVTRERR 240
INEPLDEFTGGMETLELQKDIKEESDEEEEDDEESGRLRFKTERKEGTIIRLSDVTRERR
Sbjct: 181 INEPLDEFTGGMETLELQKDIKEESDEEEEDDEESGRLRFKTERKEGTIIRLSDVTRERR 240
Query: 241 NIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGR 300
NIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGR
Sbjct: 241 NIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGR 300
Query: 301 MKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMH 360
MKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMH
Sbjct: 301 MKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMH 360
Query: 361 MPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFP 420
MPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFP
Sbjct: 361 MPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFP 420
Query: 421 GPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQR 480
GPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQR
Sbjct: 421 GPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQR 480
Query: 481 SPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI 540
SPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI
Sbjct: 481 SPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI 540
Query: 541 LHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQ 600
LHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQ
Sbjct: 541 LHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQ 600
Query: 601 PPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPH 660
PPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPH
Sbjct: 601 PPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPH 660
Query: 661 VQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIE 720
VQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIE
Sbjct: 661 VQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIE 720
Query: 721 MSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEF 780
MSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEF
Sbjct: 721 MSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEF 780
Query: 781 PDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPP 840
PDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPP
Sbjct: 781 PDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPP 840
Query: 841 AEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANM 900
AEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANM
Sbjct: 841 AEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANM 900
Query: 901 QYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTK 960
QYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTK
Sbjct: 901 QYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTK 960
Query: 961 PGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQP 1020
PGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQP
Sbjct: 961 PGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQP 1020
Query: 1021 ARKVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGR 1080
ARKVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGR
Sbjct: 1021 ARKVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGR 1080
Query: 1081 LMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPIQSLQMLPQQRKAIAKF 1140
LMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPIQSLQMLPQQRKAIAKF
Sbjct: 1081 LMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPIQSLQMLPQQRKAIAKF 1140
Query: 1141 KEPAHALAFQQKFHRHMIDLSHINVALIVE 1170
KEPAHALAFQQKFHRHMIDLSHINVALIVE
Sbjct: 1141 KEPAHALAFQQKFHRHMIDLSHINVALIVE 1170
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 160 bits (404), Expect = 9e-39
Identities = 184/691 (26%), Positives = 258/691 (37%), Gaps = 169/691 (24%)
Query: 247 ELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRP 306
E S+E+ ++ E E E K S++ G G +Q++ + P
Sbjct: 704 ESSSESSSSDSEDSETEMAPK-----SKKKGHPGR--------EQKKHHHHHHQQMQQAP 750
Query: 307 ALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLE 366
A +P QPP PQ PPPPPPP QQQ QP P P PP M PQ
Sbjct: 751 APVPQQPPPPPQQPPPPPPPQQQQ------QPPP------------PPPPPSM---PQQA 789
Query: 367 TPRMMMTPPP-VTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEF 425
P M +PPP + Q P + P G+V P+ P+ P+P + P P PPE
Sbjct: 790 APAMKSSPPPFIATQVPV---LEPQLPGSVFDPIGHFTQPILHLPQPEL-PPHLPQPPEH 845
Query: 426 --PQH-------TPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLF 476
P H +P + N+ Q P P PP P ++ P P
Sbjct: 846 STPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ--- 902
Query: 477 LEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQ-QGQQPVFPRERPVRPALQPP 535
PP PP LL P PL Q Q Q QP P V+ QPP
Sbjct: 903 -----PPMAQPPQVLLEDEEP--PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP 955
Query: 536 GPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQ 595
P +PP P H Q PP PPP QPQP
Sbjct: 956 PP-----------------LPP-------------PPHPSVQQQLQQQPPPPPPPQPQPP 985
Query: 596 -QPQQQPPPQ-------------HQPP----HQPPHQPPPQHQPPPQHP-PQHPPQHQHH 636
Q Q QPPP+ QPP QPPH PP Q PPPQ PQ QH H
Sbjct: 986 PQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHS 1045
Query: 637 HHHH--------HLSVPPPPLMPMS--QPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTT 686
HH HL P PLM S QF+ + PQ + P++Q LR
Sbjct: 1046 PRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQ----PKKQELR---A 1098
Query: 687 SQNVSKRPMQQMQPTAPRNSNLRELPIAPS----------------HVIEMSSSRCSATP 730
+ V +P+ ++ + +R P +PS H+ + +
Sbjct: 1099 ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG 1158
Query: 731 SAQVKPIVSASPPSRAVAGSRSSQG-------KTEVKVK------------PASPVAQPK 771
++P +PP A + Q K ++K+K P +P + K
Sbjct: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAK 1218
Query: 772 EEAKTETEFP----DEDEETRLYRLKIE----EQKRLREEILKQKELRRQ-QQAGARKKE 822
+ + +F +++E + + + E E++RLR+E ++ +E +QA +E
Sbjct: 1219 SSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEE 1278
Query: 823 LLERLAQQQQQLYAPPPPAEQEEQALSPSPT 853
R QQQQQ +Q+ A++ + T
Sbjct: 1279 ARRRQEQQQQQRQEQQQQQQQQAAAVAAAAT 1309
Score = 71.2 bits (173), Expect = 5e-12
Identities = 106/480 (22%), Positives = 165/480 (34%), Gaps = 71/480 (14%)
Query: 590 HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPL 649
H QQ QQ P P Q P PP QPPP PPPQ Q PP PPPP
Sbjct: 739 HHHHHQQMQQAPAPVPQQPPPPPQQPPPP--PPPQQQQQPPPP------------PPPPS 784
Query: 650 MPMSQPQFRPHVQTAQPQASSSRMQC--PQRQG-----LRHNTTSQNVSKRPMQQMQPTA 702
MP Q P ++++ P ++++ PQ G + H T Q + P ++ P
Sbjct: 785 MPQ---QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFT--QPILHLPQPELPPHL 839
Query: 703 PRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASP-PSRAVAGSRSSQGKTEVKV 761
P+ P H + + +A P +P A+ P + S T+ +
Sbjct: 840 PQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPL 899
Query: 762 KPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKK 821
P P+AQP + + E P + +L +++ ++++ ++
Sbjct: 900 LPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVK---------- 949
Query: 822 ELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDV 881
Q Q PPPP +Q L P P P P Q + R V
Sbjct: 950 ------VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR------PV 997
Query: 882 SISNVQPKTSNFVPSSANMQY-----QGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPA 936
+ +Q T P Q GQQ + + + + + HK P
Sbjct: 998 HLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTG 1057
Query: 937 DVEE---PAVPQTPRVASIQGRPQDTKPGVK-RTVTHRTNSGGGDGPHISSKVRVIKLSG 992
+ E P + +P+++ Q + P + + P V+ K+
Sbjct: 1058 HLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHS 1117
Query: 993 GGGESDGFF---------HPEG--QPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGP 1041
S+ F HPE P LPQ PE+ P + + PP P P
Sbjct: 1118 PIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP--PGAP 1175
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/187 (23%), Positives = 67/187 (35%), Gaps = 31/187 (16%)
Query: 283 LMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQ-------------- 328
+ +G G R+E+ P P Q P P PPP Q
Sbjct: 174 VQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLI 233
Query: 329 -QQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHI 387
Q P+ ++ PQPLQ PV PPQ PP P+ + + PP+ P+ +
Sbjct: 234 VQTPVMTVVPPQPLQTPPPV-------PPQPQ--PPPAPAPQPVQSHPPIIAATPQPVKT 284
Query: 388 NPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQD 447
K T + P+ P++ P+ P + Q P +PP+ + D
Sbjct: 285 KKGVKRKADTTTPTTIDPI--HEPPSLPPE--PKTTKLGQRRESSRP---VKPPKKDVPD 337
Query: 448 QWRAPPP 454
+ P P
Sbjct: 338 SQQHPAP 344
Score = 40.4 bits (93), Expect = 0.010
Identities = 40/148 (27%), Positives = 50/148 (33%), Gaps = 18/148 (12%)
Query: 574 TQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPP---QHPPQHP 630
T PN PP QP P Q P P Q P PP Q PP P
Sbjct: 195 TVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVP 254
Query: 631 PQHQHHHHHHHLSVPPPPLMPMSQP-QFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQN 689
PQ P PP P QP Q P + A PQ ++ ++ TT
Sbjct: 255 PQ------------PQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
Query: 690 VSKRPMQQMQPTAPRNSNLRE--LPIAP 715
+ + P +P + RE P+ P
Sbjct: 303 IHEPPSLPPEPKTTKLGQRRESSRPVKP 330
Score = 40.0 bits (92), Expect = 0.013
Identities = 117/616 (18%), Positives = 195/616 (31%), Gaps = 134/616 (21%)
Query: 546 PGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQH 605
P + T +P PP Q PF +Q P+ +PP QP Q PPQ
Sbjct: 206 PQTQTPQPNPPPVQ----ATPHPFPAVTPDLIVQTPVMTVVPP----QPLQTPPPVPPQP 257
Query: 606 QPPHQPPHQPPPQHQP----------------------------PPQHPPQHPPQHQHHH 637
QPP P QP H P P PP PP+ +
Sbjct: 258 QPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
Query: 638 HHHHLSVPPPPLMPMSQ-PQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696
P P P + H + S +++C G+ ++ +
Sbjct: 318 LGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKC--CSGILKEMFAKKHAAYAWP 375
Query: 697 QMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATP---------SAQVKPIVS-----ASP 742
+P L + H ++MS+ + A V+ + S P
Sbjct: 376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPP 435
Query: 743 PSRAVAGSRSSQGKTEVK-------------------VKPASPVAQPKEEAKTETE---- 779
VA +R Q E++ V P + V P + + ++
Sbjct: 436 DHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSD 495
Query: 780 ---FPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYA 836
D+ EE R RL E Q++L+ + L + QQ +KKE ++ +++++ +
Sbjct: 496 SDSSTDDSEEERAQRL-AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK--EKKKEKHK 552
Query: 837 PPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKT--SNFV 894
E+ +++ + P P + N N + K + + + P T S
Sbjct: 553 RKEEVEENKKSKAKEPP--------PKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604
Query: 895 PSSANMQYQ-------------GQQMKALKHLRQTRTVPQSQTQPLHKVL---PIKPADV 938
M Y+ G+++ + H+ Q+R + P + +KP+ +
Sbjct: 605 DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTL 664
Query: 939 EE-----------PAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRV 987
E PQ +V I G + + + +S +
Sbjct: 665 RELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPK 724
Query: 988 IKLSGGGGESDGFFH----------PEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHL 1037
K G G H P PQ+ P PP+ P P QQPP
Sbjct: 725 SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQ-----QQQPPPP 779
Query: 1038 PAGPHAHSPVPPGIKS 1053
P P P +KS
Sbjct: 780 PPPPSMPQQAAPAMKS 795
Score = 36.6 bits (83), Expect = 0.14
Identities = 119/645 (18%), Positives = 212/645 (32%), Gaps = 124/645 (19%)
Query: 586 LPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
L P Q +P++ ++ + + H+ + + + PP + + + +
Sbjct: 528 LSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKE 587
Query: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRP----------M 695
P P+ P + S +C S +++K P +
Sbjct: 588 PAPMKSKPPPTYE----------SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHII 637
Query: 696 QQMQPTAPRNSNLRELPI-----APSHVIEM-----SSSRCSATPSAQVKPIVSASPPSR 745
Q +P+ +NSN E+ I PS + E+ S R P A+ +++ S +
Sbjct: 638 QSREPSL-KNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMK 696
Query: 746 AVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEF-PDEDEETRLYRLKIEEQKRLREEI 804
+ S S +S + + +ETE P ++ R + + +++
Sbjct: 697 GFSSSESE----------SSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQM 746
Query: 805 LKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLL----P 860
+ QQ ++ QQQQQ PPPP +QA ++ P + P
Sbjct: 747 QQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVP 806
Query: 861 FPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTV- 919
Q+ +V + + Q + + QP+ +P Q + HL Q V
Sbjct: 807 VLEPQLPGSVFDPIGHFTQPI-LHLPQPELPPHLP-------QPPEHSTPPHLNQHAVVS 858
Query: 920 --------PQSQTQPLHK--VLPIKPAD--------VEEPAVPQTPRVASIQGRPQDTKP 961
PQ ++P ++ LP KPA + P +PQ P Q +D +P
Sbjct: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
Query: 962 GVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQP-------QRLPQPP 1014
+ + + ++ + P P Q+ P PP
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978
Query: 1015 EVGPQ---------PARKVTLTRGGL------------QQPPHLPAGPHAHSPVPPGIKS 1053
PQ P R V L QQPPH P G P P +
Sbjct: 979 PPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQ 1038
Query: 1054 IQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQ 1113
+ H H + P G L P P ++ +S Q
Sbjct: 1039 VIQHH-------HSPRHHKSDPYSTGHLRE----------APSPLMIHSPQMS------Q 1075
Query: 1114 LKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMI 1158
+SL P Q++Q Q+ +A + + + ++K H +I
Sbjct: 1076 FQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPII 1120
Score = 32.7 bits (73), Expect = 2.1
Identities = 41/163 (25%), Positives = 58/163 (35%), Gaps = 29/163 (17%)
Query: 401 VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDP 460
VP S P PQ P PP Q TP P P + P L +Q PPQ
Sbjct: 196 VPNTTQASTPPQTQTPQ--PNPPPV-QATPHPFP---AVTPDLIVQTPVMTVVPPQP--- 246
Query: 461 FFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQP 520
L+ P PP P P + PV + P+ P P ++G +
Sbjct: 247 ----------------LQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKR 290
Query: 521 VFPRERP--VRPALQPPGPVGILHFSQPGS--ATTRPFIPPRQ 559
P + P +PP ++ G ++RP PP++
Sbjct: 291 KADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKK 333
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 115 bits (288), Expect = 2e-25
Identities = 165/601 (27%), Positives = 202/601 (33%), Gaps = 116/601 (19%)
Query: 296 TERGRMKDHRPALLPTQPPVVPQAP---PPPPP-----PPQQQPIRSLFQPQPLQPLLPV 347
T+ RPA P P + QAP P PP P P+ S PLQ L +
Sbjct: 437 TQASLTSPSRPASTPPDSPPL-QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495
Query: 348 QHPHHPSPPQGMHMPPQLET-----PRMMMTPPP--VTPQQPKNIHINPHFKGTVVTPVQ 400
H P P + P LET P + TPP TP + P T P+
Sbjct: 496 AS-HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT 554
Query: 401 VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGP-VPNSFSQPPRLPLQDQWRAPPPPQDRD 459
P L P P P PP P TP P P+S + PP PP
Sbjct: 555 TPHLETPPCPAPCP----LQAPPS-PLTTPPPETPSSIATPP---------PQAPPALAS 600
Query: 460 PFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTL----LNSSHPVPTQSPL-PFTQPGPAFN 514
P G+ P P + PPP PP L L + P PL P P P
Sbjct: 601 PPLQGLPSPPLSPL-------ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP--Q 651
Query: 515 QQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHT 574
V + P P PP P FS P S PP P P Q P+
Sbjct: 652 APNALAVHLLQAPFSP---PPSPPVQAPFSPPAS-------PPVSPSATPPSQA-PPSLA 700
Query: 575 QPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPP--PQHQPPPQHPPQHPPQ 632
P LQ P PP PP P P Q PPP PP Q P PP P P PP+ PP
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP- 759
Query: 633 HQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSK 692
L PP +P S P P A+P Q P ++
Sbjct: 760 ---------LLAAPPLQVPPSPPASLPMSPLAKPPP-----QAPPA-----------LAT 794
Query: 693 RPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRS 752
P+Q + +P S + P +PS + MS ATP Q P+++A P V
Sbjct: 795 PPLQAL--PSPPASFPGQAPFSPSASLPMSP---LATPPPQAPPVLAA--PLLQV----- 842
Query: 753 SQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKI-------EEQKRLREEIL 805
P SP A P +A P D RL + R L
Sbjct: 843 ----------PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
Query: 806 KQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLP--FPG 863
+L + E L + A PP + E A P+ + P P F G
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 952
Query: 864 A 864
A
Sbjct: 953 A 953
Score = 65.9 bits (159), Expect = 2e-10
Identities = 100/394 (25%), Positives = 135/394 (34%), Gaps = 50/394 (12%)
Query: 405 PVPSQPRPAVGPQRFPGPPE--FPQHTPGPVPNSFSQPPRLPL----QDQWRAPPPPQDR 458
P P P PA+ + E P+ P P ++ PR + + P P R
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 459 DPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQ 518
P G + P+ L + P P + S ++P +QP P Q +
Sbjct: 227 RP---SAGGGLQRPASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 519 QP-VFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPN 577
P V P + PAL P L P RP PP P P LP P
Sbjct: 282 PPQVTPPRKDAAPALGPLSS-SPLATPSPSGTKARPVPPPDNAATPLPAT--LPP--SPP 336
Query: 578 LQGPLHPPLPPPHQPQPQQPQQQP-PPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHH 636
L PL PL PP P Q P PP P PP P Q PP P Q H
Sbjct: 337 LATPL--PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 637 HHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696
L PP PL +S Q + + QA+ S + RQ T+ + P
Sbjct: 395 LTSPSLQAPPSPL-ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP-- 451
Query: 697 QMQPTAPRNSNLRELPIAPS------------------HVIEMSSSRCSATPSAQVKPIV 738
P +P LP +P H ++ SS S +P A + ++
Sbjct: 452 ---PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 739 SASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKE 772
PP ++SS ++ PAS P E
Sbjct: 509 --MPPLE----TQSSLAPPSLQTPPASLTTPPLE 536
Score = 37.4 bits (85), Expect = 0.084
Identities = 133/631 (21%), Positives = 189/631 (29%), Gaps = 100/631 (15%)
Query: 480 RSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPR--------------- 524
R+P PP + P SP P + PG A P+ +
Sbjct: 88 RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 525 -ERPVRPALQPPGPVGILHFSQPGSATTRPFIPPR------QPFLPGPGQPFLPTHTQPN 577
E P R AL S P T P + R + LP P P +P
Sbjct: 148 TEAPKRSALSAGAR---RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPP 201
Query: 578 LQGP------------LHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQH 625
+GP P +P Q+P + P P + P +
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 626 PPQHPPQHQHHHHHHHLSVPPPP-LMPMSQPQFRPHVQTAQP---QASSSRMQCPQRQGL 681
P+ P H S P P L + PQ P + A P SSS + P G
Sbjct: 262 TPRAPA---------HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312
Query: 682 R-HNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSA 740
+ + + P+ P +P + LP+AP SA PS Q P A
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLAT--PLPLAPPSP--------SAPPSLQTLPSPPA 362
Query: 741 SPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRL 800
+PPS+A + + ++ P+ P + P + L ++ L
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP----PSPLALSSLQATTSL 418
Query: 801 REEILKQKE-----LRRQQQAGARKKELLERLAQQQQQLYAP------PPPAEQEEQALS 849
L+ RQ QA L AP PP A+S
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 850 P--SPTNGNPLLPF-------PGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANM 900
P SP +PL P A + + L ++ S P S P N+
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538
Query: 901 QYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIK--PADVEEPAVPQTPRVASIQGRPQD 958
L+ T P +T P P++ P+ + P P+TP +SI P
Sbjct: 539 --PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP-PETP--SSIATPPPQ 593
Query: 959 TKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGP 1018
P + G P +S + P P P P P
Sbjct: 594 APPALASPPLQ-----GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP 648
Query: 1019 QPARKVTLTRGGLQQPPHLPAGPHAHSPVPP 1049
P L LQ P P P +P P
Sbjct: 649 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 679
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 113 bits (283), Expect = 9e-25
Identities = 126/395 (31%), Positives = 141/395 (35%), Gaps = 68/395 (17%)
Query: 308 LLPTQPPVVPQAPPPPPPPPQQQPIRSL-------FQPQPLQPLLPVQHPHHPSPPQGMH 360
+LP PP +P A PPPPP I L P P P + P P P G+
Sbjct: 907 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIP-PPPPLPGAGIP 965
Query: 361 MPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLP----VPSQPRPAVGP 416
+PP L P + PPP P I P G + P P LP P P P G
Sbjct: 966 LPPPL--PGAGIPPPP--PLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAG- 1018
Query: 417 QRFPGPPEFPQ---HTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPS 473
P PP P P P+P + PP PL PPPP G+ P P
Sbjct: 1019 --IPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPG----AGIPPPPPLPG 1071
Query: 474 HLFLEQRSPPPP-------PPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER 526
PPPP PPPP L + P P P P P G P P
Sbjct: 1072 -----AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1126
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586
P P GI P R IPP P LPG G P P P P PPL
Sbjct: 1127 AGIPPPPPLPGAGI----PPPPPLPRVGIPPPPP-LPGAGIP--PPPPLPGAGIPPPPPL 1179
Query: 587 P----PPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHL 642
P PP P P PPP PP P PP PP PP
Sbjct: 1180 PGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP---------GT 1230
Query: 643 SVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQ 677
+PPPPL+P+S P PQ SS + PQ
Sbjct: 1231 GIPPPPLLPVSGPPL-------LPQVGSSTLPTPQ 1258
Score = 88.2 bits (217), Expect = 4e-17
Identities = 102/309 (33%), Positives = 114/309 (36%), Gaps = 63/309 (20%)
Query: 313 PPVVPQA--PPPPP------PPPQQQPIRSLFQPQPLQ-------PLLPVQHPHHPSPPQ 357
PP +P A PPPPP PPP P + P PL P LP P P
Sbjct: 989 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1048
Query: 358 GMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLP----VPSQPRPA 413
G +PP P + PPP P I P G + P P LP P P P
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPP--PPLPGAGIPPPPPLPG 1104
Query: 414 VGPQRFPGPPEFPQH---TPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPR 470
VG P PP P P P+P + PP PL PPPP R +G+ P
Sbjct: 1105 VG---IPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPR----VGIPPPPP 1156
Query: 471 FPSHLFLEQRSPPPP------PPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPR 524
P PPPP PPPP L P P P P P G P P
Sbjct: 1157 LPGAGI----PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1212
Query: 525 E-RPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLP-----THTQPNL 578
+ PA PP P PG+ IPP P LP G P LP T P +
Sbjct: 1213 PGMGIPPAPAPPLP-------PPGTG-----IPP-PPLLPVSGPPLLPQVGSSTLPTPQV 1259
Query: 579 QGPLHPPLP 587
G L PPLP
Sbjct: 1260 CGFLPPPLP 1268
Score = 78.2 bits (191), Expect = 4e-14
Identities = 113/386 (29%), Positives = 136/386 (35%), Gaps = 72/386 (18%)
Query: 311 TQPPV--VPQAPPPPPPP---PQQQ---PIRSLFQPQPLQPLL----PVQHPHHPSPPQG 358
T PPV +P PP PP PQ + I + P+ + L P Q P PP
Sbjct: 756 TLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPS 815
Query: 359 MHMPPQLETPRMMMTPPPVTPQQPKNIH-INPHFKGTVVTPVQVPL-LPVPSQPRPAVGP 416
+ P T Q + H ++ FK + P PL S P +G
Sbjct: 816 LLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGM 875
Query: 417 QRFPGPPEFPQHTPGPVPNS-FSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHL 475
P PP P T +P++ QPP L + PPPP G+ P P
Sbjct: 876 VP-PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG----AGIPPPPPLPGAG 930
Query: 476 FLE------QRSPPPP-------PPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVF 522
L PPPP PPPP L + P+P P P P G
Sbjct: 931 ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG----I 986
Query: 523 PRERPVRPALQPPGPVGILHFSQPGSATTRP------FIPPRQPFLPGPGQPFLPTHTQP 576
P P+ A PP P PG+ P IPP P LPG G P P P
Sbjct: 987 PPPPPLPGAGIPPPP------PLPGAGIPPPPPLPGAGIPPPPP-LPGAGIP--PPPPLP 1037
Query: 577 NLQGPLHPPLP----PPHQPQPQQPQQQPPP---QHQPPHQPPHQPPPQHQPPPQHP--- 626
P PPLP PP P P PPP PP PP P PPP P
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAG 1095
Query: 627 -PQHPPQHQHHHHHHHLSVPPPPLMP 651
P PP + +PPPP +P
Sbjct: 1096 IPPPPPL-------PGVGIPPPPPLP 1114
Score = 51.2 bits (121), Expect = 6e-06
Identities = 43/130 (33%), Positives = 51/130 (39%), Gaps = 21/130 (16%)
Query: 313 PPVVPQAPPPPPPP------PQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLE 366
PP +P A PPPPP P P+ + P P P LP P P G +PP
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP--PPLPGVGIPPPPPLPGAGIPPPPP 1211
Query: 367 TPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP-RPAVGPQRFPGPPEF 425
P M + P P P P I P PLLPV P P VG P P+
Sbjct: 1212 LPGMGIPPAPAPPLPPPGTGIPP-----------PPLLPVSGPPLLPQVGSSTLP-TPQV 1259
Query: 426 PQHTPGPVPN 435
P P+P+
Sbjct: 1260 CGFLPPPLPS 1269
Score = 36.2 bits (82), Expect = 0.19
Identities = 53/224 (23%), Positives = 65/224 (29%), Gaps = 29/224 (12%)
Query: 423 PEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSP 482
P P P P +F R L A P D +S P L E R P
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTE-QALSALSDLPESLAAEPREP 290
Query: 483 PPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPP--GPVGI 540
PP P L PV LP QP + FP P A P G
Sbjct: 291 QQPPSPGGL-----PVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345
Query: 541 LHFSQPGSATTRPFIPPRQPFLPGPGQPF---LPTHTQPNLQGPLHPPLPP-PHQPQPQQ 596
+ + P P + + P G+ L + QGP P P P P Q
Sbjct: 346 DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQ 405
Query: 597 -----------------PQQQPPPQHQPPHQPPHQPPPQHQPPP 623
+Q P H P P P + +P P
Sbjct: 406 RCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
Score = 32.3 bits (72), Expect = 2.7
Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 14/72 (19%)
Query: 590 HQPQPQQPQQQPPP-------QHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHL 642
HQP Q PPP Q QP QPPH + Q +H +
Sbjct: 801 HQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSA-------FKNSC 853
Query: 643 SVPPPPLMPMSQ 654
++P PP +P ++
Sbjct: 854 NIPSPPPLPCTE 865
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 108 bits (270), Expect = 3e-23
Identities = 131/479 (27%), Positives = 174/479 (36%), Gaps = 90/479 (18%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPL------QPLLPVQHPHHPSPPQGM 359
P L P P+ P P P PP QQ P L QP PL QP++P+Q P PP
Sbjct: 708 PVLPPPSTPM-PTGPGQPAPPGQQPP--PLAQPTPLPQVLAPQPVVPLQ----PVPP--- 757
Query: 360 HMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRF 419
H+PP L + P + P Q + P P Q+P +PV P G
Sbjct: 758 HLPPYLAPASQVGAPAQLKPLQMPQAPLQP----LAQVPPQMPPIPVVPPITPLAGIDGL 813
Query: 420 PGP-PEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLE 478
P P+ P T PVP PPQ F + L
Sbjct: 814 PPALPDLPTATVPPVP-------------------PPQ-------------YFSPAVILP 841
Query: 479 QRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPV 538
+ P PP P L + +P P P P P P+ A+ PPG
Sbjct: 842 SLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTI-----VPNAPATIPLL-AVAPPGVA 895
Query: 539 GILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQ 598
+ S +P P P + P P HT N++ P PP P QP
Sbjct: 896 ALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPV 955
Query: 599 QQPPPQHQPPHQPPHQPPPQHQPPPQHPPQH--PPQHQHHHHHHHLSVPPPPLMPMSQPQ 656
PPQ P QP P P P P PPQ PPQ +PP P +P+
Sbjct: 956 L--PPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP---------VLPPQPALPVRPEP 1004
Query: 657 FRPHV-QTAQPQASSSRMQCPQRQGLRHNTTSQNV---SKRPMQQMQPTAPRNSNLRE-- 710
+PH+ + A P A+ P Q L + V ++ P + P A + L E
Sbjct: 1005 LQPHLPEQAAPAAT------PGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVL 1058
Query: 711 LPIAPSHVIEMSSSRCSATPSAQVKP------IVSASPPSRAVAGSRSSQGKTEVKVKP 763
LP AP + + SS + + S Q P + A+PP G S ++ V+P
Sbjct: 1059 LPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEP 1117
Score = 60.5 bits (145), Expect = 9e-09
Identities = 120/500 (24%), Positives = 161/500 (32%), Gaps = 69/500 (13%)
Query: 387 INPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRF-PGPPEFPQHTPGPVPNSFSQPPRLPL 445
+ P + V +P + PVP Q + Q PGPPE P+ P + PP LP
Sbjct: 550 LQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPE-PEE---PEADQHLLPPTLPT 605
Query: 446 QDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLP 505
A D S + L + P P + S PV LP
Sbjct: 606 SATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVC--SPPVSEGPVLP 663
Query: 506 FTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGIL-HFSQPGSATTRPFIPPRQPFLPG 564
+ P QQ P PV P P + HF P + PP P G
Sbjct: 664 QSLPSLGAYQQ---PTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 720
Query: 565 PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPP-------- 616
PGQP P P L P PLP PQP P Q P PH PP
Sbjct: 721 PGQPAPPGQQPPPLAQPT--PLPQVLAPQPVVPLQPVP---------PHLPPYLAPASQV 769
Query: 617 -----------PQH--QPPPQHPPQHPPQHQHHHHHHHLSVP-PPPLMPMSQPQFRPHVQ 662
PQ QP Q PPQ PP +P PP+ P++ P
Sbjct: 770 GAPAQLKPLQMPQAPLQPLAQVPPQMPP------------IPVVPPITPLAGIDGLPPAL 817
Query: 663 TAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMS 722
P A+ + PQ S P+ P P + +LP P + M
Sbjct: 818 PDLPTATVPPVPPPQYFSPAVILPS---LAAPLPPASPALPLQA--VKLPHPPGAPLAMP 872
Query: 723 SSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPD 782
A + P+++ +PP A S+ ++ +P P A P+ T+ P
Sbjct: 873 CRTIVPNAPATI-PLLAVAPPGVAALSIHSA--VAQLPGQPVYPAAFPQ---MAPTDVPP 926
Query: 783 EDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAE 842
T Q L + + Q + +L + Q PP P
Sbjct: 927 SPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPML 986
Query: 843 QEEQALSPSPTNGNPLLPFP 862
+ L P P P+ P P
Sbjct: 987 PPQPVLPPQP--ALPVRPEP 1004
Score = 48.5 bits (114), Expect = 4e-05
Identities = 59/223 (26%), Positives = 72/223 (32%), Gaps = 32/223 (14%)
Query: 432 PVPNSFSQPPRLPLQDQWRAPPPPQDRDPFF--LGVSGEPRF-PSHLFLEQRSPPPPP-- 486
P P + P LPL P QD P+ L +P F S L Q P PP
Sbjct: 1322 PAPEAPESSPPLPLSSL--PPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGA 1379
Query: 487 PPPTLLNSSHPVPT-----QSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGIL 541
PP L SS PV +P T P PA Q + + L+ P+
Sbjct: 1380 PPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAET 1439
Query: 542 HFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQP 601
H +P + P P P + P P P P PH PQ QP
Sbjct: 1440 H---EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQP 1496
Query: 602 PP------------QHQPPHQP-----PHQPPPQHQPPPQHPP 627
P Q P P P QPP + + PP
Sbjct: 1497 APLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/167 (29%), Positives = 61/167 (36%), Gaps = 41/167 (24%)
Query: 310 PTQP--PVVPQAPPPPPPPPQQQ-PIRSLFQPQPLQPLLP-------------------- 346
P QP P P PP P PPQ P+R P+PLQP LP
Sbjct: 975 PPQPVLPPQPMLPPQPVLPPQPALPVR----PEPLQPHLPEQAAPAATPGSQILLGHPAP 1030
Query: 347 ------VQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQ 400
Q P P PP + PP E ++ P + PQ P ++ +V P Q
Sbjct: 1031 YAVDVAAQVPTVPVPPAAVLSPPLPEV--LLPAAPELLPQFPSSLATVSASVQSV--PTQ 1086
Query: 401 VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPN---SFSQPPRLP 444
L P+ P P G P Q T PV S +PP LP
Sbjct: 1087 TATLLPPANP-PLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
Score = 40.8 bits (94), Expect = 0.008
Identities = 58/249 (23%), Positives = 80/249 (32%), Gaps = 38/249 (15%)
Query: 315 VVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLP-VQHPHHPSPPQ--GMHMPPQLETPRMM 371
+ P A P P P+ P P PL L P P Q P L + +++
Sbjct: 1315 ICPVAEHPAPEAPESSP------PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLL 1368
Query: 372 MTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPG 431
P P + P P + P PA G G P PQ
Sbjct: 1369 SQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTS 1428
Query: 432 PVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTL 491
+ S PL + AP Q P +G++ P P P
Sbjct: 1429 ELETS------QPLAETHEAPLAVQ---PLVVGLA-----------------PCTPAPEA 1462
Query: 492 LNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATT 551
++ + PLP P P+ + QP + P+ PA G V L SQ S
Sbjct: 1463 ASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPA--AVGAVS-LATSQLPSPPL 1519
Query: 552 RPFIPPRQP 560
P +PP+ P
Sbjct: 1520 GPTVPPQPP 1528
Score = 38.9 bits (89), Expect = 0.029
Identities = 52/194 (26%), Positives = 61/194 (31%), Gaps = 32/194 (16%)
Query: 310 PTQPPVVPQAPPPPPPPP----QQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQL 365
P+ PP P AP P PP Q P P PQG + +L
Sbjct: 1373 PSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQG--LTSEL 1430
Query: 366 ETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEF 425
ET + P T + P V P+ V L P P P R P
Sbjct: 1431 ETSQ----PLAETHEAP-----------LAVQPLVVGL--APCTPAPEAASTRDASAPRE 1473
Query: 426 PQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPP 485
P P P P+ S P+ L AP P L S P P P P
Sbjct: 1474 PLPPPAPEPSPHSGTPQPALGQP--APLLPAAVGAVSLATSQLPSPP-------LGPTVP 1524
Query: 486 PPPPTLLNSSHPVP 499
P PP+ L S P
Sbjct: 1525 PQPPSALESDGEGP 1538
Score = 33.9 bits (76), Expect = 0.93
Identities = 68/296 (22%), Positives = 91/296 (30%), Gaps = 20/296 (6%)
Query: 482 PPPPPPPPTLLNSSHPVPTQS-PLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI 540
P P P SS P+P S P +Q + Q P + L GP
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP--- 1373
Query: 541 LHFSQPGSATTRPFIPPRQPFLPGPGQPFLP-THTQPNLQGPLHPPLPPPHQPQPQQPQQ 599
S P A P P P P P T T P P PQ +
Sbjct: 1374 ---SNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSEL 1430
Query: 600 QPPPQHQPPHQPPH--QPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQF 657
+ H+ P QP P P+ S P PL P + P+
Sbjct: 1431 ETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRD-------ASAPREPLPPPA-PEP 1482
Query: 658 RPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSH 717
PH T QP P G TSQ + P+ P P ++ + P
Sbjct: 1483 SPHSGTPQPALGQPAPLLPAAVGAVSLATSQ-LPSPPLGPTVPPQPPSALESDGEGPPPR 1541
Query: 718 VIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEE 773
V + S+ S + P S A AG+ G + ++P QP+ E
Sbjct: 1542 VGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRG-DQPRSE 1596
Score = 32.3 bits (72), Expect = 2.7
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 21/124 (16%)
Query: 272 SSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQP 331
+S + GGP +G+ + S + + A L QP VV AP P P +
Sbjct: 1410 ASGTASQAGGPGTPQGLTSELETSQP---LAETHEAPLAVQPLVVGLAPCTPAP--EAAS 1464
Query: 332 IRSLFQP-QPLQPLLPVQHPHHPSPPQGMHMP---------------PQLETPRMMMTPP 375
R P +PL P P PH +P + P QL +P + T P
Sbjct: 1465 TRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVP 1524
Query: 376 PVTP 379
P P
Sbjct: 1525 PQPP 1528
Score = 31.6 bits (70), Expect = 4.6
Identities = 35/147 (23%), Positives = 57/147 (38%), Gaps = 20/147 (13%)
Query: 919 VPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSG---- 974
+P T+P VLP +P +P +P P ++ RP+ +P + G
Sbjct: 968 LPPQPTRPPQPVLPPQPMLPPQPVLPPQP---ALPVRPEPLQPHLPEQAAPAATPGSQIL 1024
Query: 975 -GGDGPH---ISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGG 1030
G P+ ++++V + + P LP PE+ PQ +
Sbjct: 1025 LGHPAPYAVDVAAQVPTVPVPPA-----AVLSPPLPEVLLPAAPELLPQFPSSLATVSAS 1079
Query: 1031 LQQPPHLPAG--PHAHSPVP--PGIKS 1053
+Q P A P A+ P+P PGI S
Sbjct: 1080 VQSVPTQTATLLPPANPPLPGGPGIAS 1106
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 108 bits (269), Expect = 4e-23
Identities = 144/521 (27%), Positives = 184/521 (35%), Gaps = 115/521 (22%)
Query: 313 PPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMM 372
PP+ P PPPPPPPP P P P PL P +P G P M +
Sbjct: 626 PPLPP--PPPPPPPPPPPP------PPPPPPL-----PSQSAPSAGSAAP-------MFV 665
Query: 373 TPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPS-QPRPAVGPQRF--PGPPEFPQHT 429
+T Q + H G + P P++ S +P+ V P P PP P T
Sbjct: 666 KYSTITRLQNASQH-----SGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 430 PGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPP 489
PG P P Q+ APPPP + + Q +PP PPPPP
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPL-------------KIHQVQHITQVAPPTPPPPP 767
Query: 490 TLLNSSHPVPTQSPLP--FTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPG 547
+ P+P Q+P T P P + + PV + P P PP P + P
Sbjct: 768 PI---PAPLPPQAPPKPLVTIPAPT-STKTVAPVVTQAAPPTPT--PPVPPAKKQPAFPA 821
Query: 548 SATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQP----QQPQQQPPP 603
S +IPP P P P +P T P Q P P P P P Q Q PPP
Sbjct: 822 S-----YIPPSPPTPPVP----VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872
Query: 604 QHQP-----PHQP------PHQPPPQHQPPPQHPPQHP---PQHQHHHHHHHLSVPPPPL 649
P P +P P PP P P P P L PPPP
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 650 MPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLR 709
P+ P P TA P S G + + TS K+P PT RNS+++
Sbjct: 933 SPVPAPP-PPPPPTASPTPDKS-----GSPGKKTSKTSSPGGKKP----PPTPQRNSSIK 982
Query: 710 ----------ELPIAPSHVIEMSSSRCSATPSAQVKPIVSASP-PSR------------- 745
+ P S V + + S +PS + P +A P P +
Sbjct: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042
Query: 746 -----AVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFP 781
A A S +GK V P+ P ETE P
Sbjct: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP 1083
Score = 97.4 bits (241), Expect = 7e-20
Identities = 103/351 (29%), Positives = 124/351 (35%), Gaps = 49/351 (13%)
Query: 305 RPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHM--- 361
+P +L VVP PPPPPPP + L +P P P LP P PP +H
Sbjct: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQL-KPAPCAPSLP--QFSAPPPPLKIHQVQH 754
Query: 362 -----PPQLETPRMMMTP-PPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVG 415
PP P + P PP P +P P TV V P P+ P P
Sbjct: 755 ITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814
Query: 416 PQ-RFPGP--PEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFP 472
Q FP P P P PVP PP LP Q + A PPP P P
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVP-----PPTLPKQQSFCAKPPPSPLSP----------VP 859
Query: 473 SHL-FLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPA 531
S + + + PPPP PP PVP + P + P + Q P P P
Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPA-NVAPQSPPAVKAKPKWQPSSIPVPSPDFP- 917
Query: 532 LQPPGPVGILHF-SQPGSATTRPFIPPRQPFLPGP---GQPFLPTHTQPNLQGPLHPPLP 587
PP P L F P S P PP P P G P T + G PP P
Sbjct: 918 --PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Query: 588 P----------PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQ 628
P+P++P P P + PPP PP+
Sbjct: 976 QRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPK 1026
Score = 84.0 bits (206), Expect = 8e-16
Identities = 128/534 (23%), Positives = 189/534 (35%), Gaps = 102/534 (19%)
Query: 304 HRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPV---QHPHHPSPPQGMH 360
H + P PP P P P PP +P+ ++ P + + PV P P+PP
Sbjct: 754 HITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP---- 809
Query: 361 MPP---QLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ 417
+PP Q P + P P TP P P + P PL PVPS +
Sbjct: 810 VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA--S 867
Query: 418 RFPGPPEFP---QHTPGPVPNSFS--QPPRLPLQDQWRA----------PPPPQDRDPFF 462
+FP PP P PVP + + PP + + +W+ PPPP + F
Sbjct: 868 QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF 927
Query: 463 LGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVF 522
P PS + PPPPPPPT + P P +S P + + G++P
Sbjct: 928 -----PPPPPSPV-----PAPPPPPPPT----ASPTPDKSGSPGKKTSKTSSPGGKKPPP 973
Query: 523 PRER--------------PVRPALQPPGPVGILHFSQP---GSATTRPFIPPRQPFLPGP 565
+R P RP++ + F+ P GS + PP P P P
Sbjct: 974 TPQRNSSIKSSSGAEHPEPKRPSVDSL----VSKFTPPAESGSPSKETLPPPAAP--PKP 1027
Query: 566 GQPFLPTHTQPNL--QGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPP 623
G+ L P + QG + P + P PP PPP P
Sbjct: 1028 GKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFP----SPPSDSDFPPPPPETELP 1083
Query: 624 QHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRH 683
P + P + V P P Q + V+ A P R + L
Sbjct: 1084 LPPIEIPAVFSGNTSPKVAVVNPQP-----QQWSKMSVKKAPPPTRPKRNDSTR---LTQ 1135
Query: 684 NTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMS--------------SSRCS-A 728
S+ + + PT+P++S L + P + +++ SSR S A
Sbjct: 1136 AEISEQPTMATVVPQVPTSPKSS----LSVQPGFLADLNRTLQRKSITRHGSLSSRMSRA 1191
Query: 729 TPSAQVKPIVSASPPSRAV-----AGSRSSQGKTEVKVKPASPVAQPKEEAKTE 777
P+A + + PP + AG S ++ P A PK + T+
Sbjct: 1192 EPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNTK 1245
Score = 68.9 bits (167), Expect = 3e-11
Identities = 126/580 (21%), Positives = 186/580 (32%), Gaps = 132/580 (22%)
Query: 465 VSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQ----- 519
+S +P+ + Q SPP PPPPP P P P P P P +Q
Sbjct: 609 LSPQPKIVTPYTASQPSPPLPPPPP-------PPPPPPPPPPPPPPPLPSQSAPSAGSAA 661
Query: 520 PVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQ 579
P+F + + + + SQ A +P PP Q +P PN
Sbjct: 662 PMFVKYSTI---------TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP----PNGV 708
Query: 580 GPLHPPLPPPHQP------------QPQQPQQQPPPQHQPPHQPPH---QPPPQHQPPPQ 624
P PP PPP P P PQ PP HQ H PP PPP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 625 HPPQHPPQHQHHHHHHHLSVPPPPLM----PMSQPQFRPHVQTAQPQASSSRMQCPQRQ- 679
P PPQ PP PL+ P S P V A P + + ++Q
Sbjct: 769 IPAPLPPQ-----------APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQP 817
Query: 680 GLRHNTTSQNVSKRPMQQMQPTAPRNSNL----RELPIAP-SHVIEMSSSRCSATPSAQV 734
+ + P+ PT P+ + P++P V++ +S+ P+
Sbjct: 818 AFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT--- 874
Query: 735 KPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKI 794
P S P + V + + Q VK KP QP +FP E+ L
Sbjct: 875 -PPAMESQPLKPVPANVAPQSPPAVKAKPK---WQPSSIPVPSPDFPPPPPESSL----- 925
Query: 795 EEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTN 854
++ PPPP+ P PT
Sbjct: 926 ---------------------------------------VFPPPPPSPVPAPPPPPPPT- 945
Query: 855 GNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLR 914
+P G+ ++ K + P+ ++ + SS+ ++ + ++ L
Sbjct: 946 ASPTPDKSGSPGKKTSK----TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLV 1001
Query: 915 QTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSG 974
T P P + LP PA P P ++ G PGV +
Sbjct: 1002 SKFTPPAESGSPSKETLP-------PPAAPPKPGKLNLSG---VNLPGVL-----QQGCV 1046
Query: 975 GGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPP 1014
P +S + + + SD F P LP PP
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPP 1086
Score = 57.8 bits (138), Expect = 6e-08
Identities = 114/518 (22%), Positives = 164/518 (31%), Gaps = 97/518 (18%)
Query: 586 LPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
L PP PQP+ Q PP PP PPP PPP PP P
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPP--PPPPPPPPPPPPP-----------------P 645
Query: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQ-CPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704
PPPL S P ++ +R+Q Q G + V + + Q P
Sbjct: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705
Query: 705 NSNLRELPIAPSHVIEMSS-SRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKP 763
N + P P S+ ++ P A P SA PP + Q + +V P
Sbjct: 706 NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI-----HQVQHITQVAP 760
Query: 764 ASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKEL 823
+P P A + P + T A K +
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVT--------------------------IPAPTSTKTV 794
Query: 824 LERLAQQQQQLYAPPPPAEQEEQA-----LSPSPTNGNPLLPFPGAQVRQNVKNRLLVKN 878
+ Q PP P +++ A + PSP +P P +Q+ +
Sbjct: 795 APVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSP 854
Query: 879 QDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHK--VLPIKPA 936
S V+ S F P + Q +K + ++ P + +P + +P+
Sbjct: 855 LSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP 914
Query: 937 DVEEP--------------AVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHIS 982
D P VP P P K G T +T+S GG P +
Sbjct: 915 DFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT 974
Query: 983 SKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGPH 1042
+ S G E HPE P+ P V ++ G LP P
Sbjct: 975 PQRNSSIKSSSGAE-----HPE------PKRPSVDSLVSKFTPPAESGSPSKETLP--PP 1021
Query: 1043 AHSPVP----------PGIKSIQGIHPAKKAIMHGRGR 1070
A P P PG+ QG AK ++ GRG+
Sbjct: 1022 AAPPKPGKLNLSGVNLPGVLQ-QGCVSAKAPVLSGRGK 1058
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 105 bits (263), Expect = 2e-22
Identities = 130/495 (26%), Positives = 186/495 (37%), Gaps = 61/495 (12%)
Query: 303 DHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMP 362
+ P P + P P P PPP+ P+ F+ PL P P + P P P P
Sbjct: 516 EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP-PPEELPTSPPPEASRLSP 574
Query: 363 PQLETPRMMMTPPPVTPQQ--PKNIHINPHFKGTVVT--PVQVPLLPVPSQPRPAVGPQR 418
P E+P M PP +P P+ + P F+ + ++ P + PL P P R + P+
Sbjct: 575 PPEESP--MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED 632
Query: 419 FPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPP------PPQDRDPFFLGVSGEPRFP 472
P P P+ +P P S+ LP+ + PP PP + P + P
Sbjct: 633 SPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP-----TSPPPEA 686
Query: 473 SHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPAL 532
S L P PPP S P + LP + P + + PR +
Sbjct: 687 SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL-EESPLLPLPEEPQLCPRSEGPHLSP 745
Query: 533 QPPGPVGILHFSQPGSATTRPFIPPR--QPFL-PGPGQPFL-----PTHTQPNLQGPLHP 584
+P P H S P + P+ +P L P P +P L H P +GP
Sbjct: 746 RPEEP----HLS---PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLS 798
Query: 585 PLPPP--HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHL 642
P P PQ ++P P P+ +P P QP H P P P+ + H L
Sbjct: 799 PQPEELHLSPQTEEPHLSPVPE-EPCLSP--QPEESHLSPQSEEPCLSPRPEESHLSPEL 855
Query: 643 SVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPM----QQM 698
PPL P RP +P QCP + L S P+
Sbjct: 856 E--KPPLSP------RPEKPPEEPG------QCPAPEELPLFPPPGEPSLSPLLGEPALS 901
Query: 699 QPTAPRNSNL-RELPIAPSHVIEMSSSRCSATP-SAQVKPIV-SASPPSRAVAGSRSSQG 755
+P P S L ELP++PS +S P + PI+ +A+PP+ + G
Sbjct: 902 EPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF 961
Query: 756 KTEVKVKPASPVAQP 770
+ P SP+A P
Sbjct: 962 GAKGDSDPESPLAAP 976
Score = 95.1 bits (235), Expect = 3e-19
Identities = 151/599 (25%), Positives = 203/599 (33%), Gaps = 94/599 (15%)
Query: 265 QHKQGRYSSRRGGRRGGPLMCR----GVGDQRRESTERGRMKDHRPALLPTQ-----PPV 315
Q K G +S + + GPL C G + E + + P L P + PP
Sbjct: 395 QPKGGHVTSMQP-KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPP 453
Query: 316 VPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPP 375
PPP + P PL L + P SP PP E+P + PP
Sbjct: 454 EESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLS----PPPEESP--LSPPP 507
Query: 376 PVTPQQP-KNIHINPHFKGTVVTPVQVPLLPVP--SQPRPAVGPQRFPGPPEFPQHTPGP 432
+P P + ++P + ++ PL P P S P PPE +P P
Sbjct: 508 ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP 567
Query: 433 VPNSFSQPPR-----LPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP 487
+ S PP P ++ +PPP R F P P + SP PPP
Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASR--LFPPFEESPLSPP----PEESPLSPPP 621
Query: 488 ------PPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVF------PRERPVRP----- 530
PP + P P +SP+ P P ++ PV P E P+ P
Sbjct: 622 EASRLSPPPEDSPMSPPPEESPM---SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES 678
Query: 531 ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPF--LPTHTQPNLQGPLHPPLPP 588
PP L S T+ P P P P P LP P L P P L P
Sbjct: 679 PTSPPPEASRLSPPPEDSPTSPP--PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
Query: 589 ----PH-QPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHP-----PQHP-------- 630
PH P+P++P P P+ PH P P P P+ P P+ P
Sbjct: 737 RSEGPHLSPRPEEPHLSPRPEE--PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
Query: 631 ----PQHQHHH-----HHHHLS-VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQG 680
PQ + H HLS VP P + + Q+ +P S +
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Query: 681 LRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSA 740
L S K P + Q AP L P PS + S + P+
Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEE 914
Query: 741 SPPSRAVAGSRSSQ-GKTEVKVKPASPV----AQPKEEAKTETEFP-----DEDEETRL 789
P S + S S Q + P SP+ A P E E+P D D E+ L
Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPL 973
Score = 90.9 bits (224), Expect = 6e-18
Identities = 94/346 (27%), Positives = 128/346 (36%), Gaps = 55/346 (15%)
Query: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQP-LQPLLPVQHPHHPSPPQGMHMPPQLETP 368
P +P + PQA P P ++P +P L P + PH P+ +H+ PQ E P
Sbjct: 756 PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP--QAEGPHLSPQPEELHLSPQTEEP 813
Query: 369 RMMMTPP-PVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQ 427
+ P P QP+ H++P + ++P P +P + P+ PE P
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR-----PEKPP 868
Query: 428 HTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP 487
PG P P LPL PPP + P + GEP S P PP
Sbjct: 869 EEPGQCP----APEELPL-----FPPPGE---PSLSPLLGEPAL---------SEPGEPP 907
Query: 488 PPTLLNSSHPVPTQSPL-PFTQPGPAFNQQGQQPVFPRERPVRPALQPPG--PVGILHFS 544
P+P + PL P +P + P+ P P+ A PP P+G L +
Sbjct: 908 -------LSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960
Query: 545 QPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQ 604
+ P P P L P P P P+ P + PP P P +
Sbjct: 961 FGAKGDSDPESPLAAPILETPISP--PPEANCTDPEPVPPMILPPSPGSPVGPASPILME 1018
Query: 605 HQPPHQPP---HQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPP 647
PP P H PQ+ PP Q P P LSVP P
Sbjct: 1019 PLPPQCSPLLQHSLVPQNSPPSQCSPPALP----------LSVPSP 1054
Score = 89.4 bits (220), Expect = 2e-17
Identities = 151/633 (23%), Positives = 212/633 (33%), Gaps = 102/633 (16%)
Query: 422 PPEFPQHTPGPVPNSF-----SQPPRLPLQDQWRAPPPPQDRDPFFLGVSG---EPRFPS 473
PPE P TP P++ QP + P P + LG +G EP+ +
Sbjct: 374 PPE-PGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432
Query: 474 HLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQ 533
L E PPP P P P +SP T P P ++ P P+ AL
Sbjct: 433 PLNEEMPLLPPPEESPL-----SPPPEESP---TSPPPEASRLSPPPEELPASPLPEALH 484
Query: 534 PPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPN---LQGPLHPP----- 585
P+ S P + P PF P P P P L+ PL PP
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544
Query: 586 LPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQH---QPPPQHPPQHPPQHQHHHHHHHL 642
L PP + P P + P PP PPP+ PPP+ P PP
Sbjct: 545 LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR------ 598
Query: 643 SVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTA 702
PP P+S P P P +SR+ P +S P +
Sbjct: 599 LFPPFEESPLSPP---PEESPLSPPPEASRLSPPPE--------DSPMSPPPEESPMSPP 647
Query: 703 PRNSNLRELPIAPSHVIEMSSSRCSATP-SAQVKPIVSASPPSRAVAGSRSSQGKTEVKV 761
P S L LP+ SR S P + + P SP S SR S +
Sbjct: 648 PEVSRLSPLPVV---------SRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Query: 762 KPA---SPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGA 818
P SP + P E++ EE+ L L E Q R E +
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPL----EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
Query: 819 RKKELLERLAQQQQQLYAPPPPAE------QEEQALSPSPTNGNPLLPFP-GAQVRQNVK 871
R +E L+ Q ++ + P P E EE LSP G L P P + +
Sbjct: 755 RPEE--PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ-AEGPHLSPQPEELHLSPQTE 811
Query: 872 NRLLVKNQDVSISNVQPKTSNFVPSSAN--MQYQGQQMKALKHLRQTRTVPQSQTQPLHK 929
L + + QP+ S+ P S + + ++ L + P+ + P
Sbjct: 812 EPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871
Query: 930 VLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIK 989
P ++ P P ++ + G P ++PG P +S +
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPG---------------EPPLSPLPEELP 916
Query: 990 LSGGGGESDGFFHPEGQPQRLPQ--PPEVGPQP 1020
LS P G+P PQ PP+ P P
Sbjct: 917 LS-----------PSGEPSLSPQLMPPDPLPPP 938
Score = 66.2 bits (160), Expect = 2e-10
Identities = 98/357 (27%), Positives = 123/357 (34%), Gaps = 95/357 (26%)
Query: 323 PPPPPQQQPIRSLFQPQPLQPL------LPVQHPHHPSPPQGMHMPPQLET--------P 368
PP P Q P + F P PL P +P +PSP PP L P
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
Query: 369 RMMMTPPPVTPQ-QPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFP--GPPEF 425
T PP TP+ QP +P K + + L VP P G P PP F
Sbjct: 2224 GEFHTTPPGTPRHQPST--PDPFLKPRCPS---LDNLAVPESPGVGGGKASEPLLSPPPF 2278
Query: 426 PQH----------------TPGPVPNSFSQPP---------RLPLQDQWRAPPPPQDRDP 460
+ + GP F P L D ++AP P+
Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPR---- 2334
Query: 461 FFLGVSGEPRFPSHLFLEQRSPPP----PPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQ 516
EP+ P L L + PPP P PP SHP +PG +
Sbjct: 2335 ---ASQVEPQSPG-LGLRPQEPPPAQALAPSPP-----SHP-------DIFRPGSYTDPY 2378
Query: 517 GQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQP 576
Q P+ PR QPP P P P PF P P +Q
Sbjct: 2379 AQPPLTPRP-------QPPPP--------ESCCALPPRSLPSDPFSRVPASP----QSQS 2419
Query: 577 NLQGPLHP-PL-PPPHQPQPQQPQ-QQPPPQHQPPHQPPHQPP--PQHQPPPQHPPQ 628
+ Q PL P PL P P P+ Q P P +PP +P + P P H+PP PP+
Sbjct: 2420 SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPE 2476
Score = 64.7 bits (156), Expect = 5e-10
Identities = 93/367 (25%), Positives = 127/367 (34%), Gaps = 66/367 (17%)
Query: 272 SSRRGGRRGGPLMCRGVGDQRRE-STERGRMKDHRPAL----LPTQPPVVPQAPPPP--P 324
SSR G + G G R + ST +K P+L +P P V P
Sbjct: 2215 SSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLS 2274
Query: 325 PPPQQQPIRSL-FQPQPLQPLLPVQHPHH----PSPPQGMHMPP-QLETPRMMMTPPPVT 378
PPP + ++L + + L P P + SP G H+ +L+TP + P
Sbjct: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAP---- 2330
Query: 379 PQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQ-HTPGPVPNSF 437
P+ + P G + P + P P A+ P PP P PG + +
Sbjct: 2331 -LTPRASQVEPQSPGLGLRPQEPP-------PAQALAPS----PPSHPDIFRPGSYTDPY 2378
Query: 438 SQPPRLPLQDQWRAPPPPQD---RDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNS 494
+QPP P PPPP+ P L R P+ + S P P P +
Sbjct: 2379 AQPPLTPRPQ----PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434
Query: 495 SHPVPT----QSPLPFTQPGPAFNQQGQQPVFPRERPVRP-------------------- 530
P P QSP P+++P Q + P P +P RP
Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPS--RPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG 2492
Query: 531 ---ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLP 587
A P GP G LH P P G P T Q + L PP+P
Sbjct: 2493 GFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552
Query: 588 PPHQPQP 594
P P P
Sbjct: 2553 QPGLPPP 2559
Score = 63.5 bits (153), Expect = 1e-09
Identities = 88/315 (27%), Positives = 115/315 (36%), Gaps = 62/315 (19%)
Query: 312 QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP---HHPSPPQGMHMPPQLETP 368
+P + PQ PP P PP PI + P L PL +++P S P+ P LETP
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP 981
Query: 369 RMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ----RFPGPPE 424
++PPP + P VP + +P P VGP P PP+
Sbjct: 982 ---ISPPP---------------EANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Query: 425 ---FPQHT--PGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQ 479
QH+ P P S PP LPL + P P +GVS E + E+
Sbjct: 1024 CSPLLQHSLVPQNSPPSQCSPPALPL-----SVPSPLSPIGKVVGVSDEAEL-HEMETEK 1077
Query: 480 RSPPPPPPPPTLLNSSHPVPTQSPL-----PFTQPGPA---FNQQGQQPVFPRERPVRPA 531
S P P L S P SP+ P P PA F+ G+ P + P
Sbjct: 1078 VSEPECP----ALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTA-PLDGIDAPG 1132
Query: 532 LQP-PGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQ--PFLPTHTQPNLQGPLHPPLPP 588
QP PG PGS + P L P + P P P + P
Sbjct: 1133 SQPEPG-------QTPGSLASE---LKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPC 1182
Query: 589 PHQPQPQQPQQQPPP 603
Q +P+ P PP
Sbjct: 1183 EEQEEPRAPVAPTPP 1197
Score = 58.2 bits (139), Expect = 5e-08
Identities = 103/363 (28%), Positives = 127/363 (34%), Gaps = 63/363 (17%)
Query: 279 RGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQ--QPIRSLF 336
+GGPL + +TE G +K P+L ++ Q P P P Q P+R
Sbjct: 4045 QGGPLAIGTTPESM--ATEPGEVK---PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPG 4099
Query: 337 QPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVV 396
Q Q LL P ++ P QP ++ N +
Sbjct: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQN-------L 4152
Query: 397 TPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPR---LPLQDQWRAPP 453
Q P+L P Q GPQ PP+ PGPV S P +P Q RA
Sbjct: 4153 LGPQQPMLERPMQNN--TGPQ----PPK-----PGPVLQSGQGLPGVGIMPTVGQLRAQ- 4200
Query: 454 PPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPL--PFTQPGP 511
GV + HL +Q+ L S V P P TQ P
Sbjct: 4201 --------LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP 4252
Query: 512 AFNQQGQQPVFPRERPVRPALQPPGP-VGILHFSQPGSATTRPFIPPRQPFLPGPGQPFL 570
G QP PGP G L Q A RP PPR P PG
Sbjct: 4253 LQGLLGCQPQLGGF---------PGPQTGPL---QELGAGPRPQGPPRLPAPPGA----- 4295
Query: 571 PTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQH--QPPPQHPPQ 628
T P L GP+HP PP +P++P Q P P Q P + Q PP H P PQ P
Sbjct: 4296 -LSTGPVL-GPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEA--QLPPTHPGTPKPQGPTL 4351
Query: 629 HPP 631
PP
Sbjct: 4352 EPP 4354
Score = 57.0 bits (136), Expect = 1e-07
Identities = 106/437 (24%), Positives = 142/437 (32%), Gaps = 86/437 (19%)
Query: 302 KDHRPAL---LPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPL-LPVQHPHHPSPPQ 357
K RPAL +P QP + PP P ++F P P L PP
Sbjct: 2096 KTDRPALHLRIPPQPGALGSPPPAAAP--------TIFIGSPTTPAGLSTSADGFLKPPA 2147
Query: 358 GMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ 417
G P + PP V Q P Q P P+ P P
Sbjct: 2148 GSVPGPDSPGELFLKLPPQVPAQVPS----------------QDPFGLAPAYPLEPRFPT 2191
Query: 418 RFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHL-- 475
P P +P T P +QPP L + A P + F G PR
Sbjct: 2192 APPTYPPYPSPTGAP-----AQPPMLGASSRPGAGQPGE----FHTTPPGTPRHQPSTPD 2242
Query: 476 -FLEQRSPP----PPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRP 530
FL+ R P P P + P SP PF + A + ++ +
Sbjct: 2243 PFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEE--------LGA 2294
Query: 531 ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGP---LHPPLP 587
+ GP + P S T + + P + P P +Q Q P L P P
Sbjct: 2295 SSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKA--PLTPRASQVEPQSPGLGLRPQEP 2352
Query: 588 PPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPP 647
PP Q P P H +P P QPP PQ PP ++PP
Sbjct: 2353 PPAQALAPSP-----PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPES------CCALPPR 2401
Query: 648 --PLMPMSQPQFRPHVQTAQ-----PQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
P P S+ P Q++ P+ S+ CP R S + RP P
Sbjct: 2402 SLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ--SPDPYSRP-----P 2454
Query: 701 TAPRNSNLRELPIAPSH 717
+ P++ + P AP H
Sbjct: 2455 SRPQSRD----PFAPLH 2467
Score = 51.6 bits (122), Expect = 4e-06
Identities = 83/338 (24%), Positives = 132/338 (39%), Gaps = 55/338 (16%)
Query: 644 VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQR--QGLRHNTTSQNVSKRPMQQMQPT 701
V P PL P +P P ++P+ +S + + +G RH + Q P + P
Sbjct: 3089 VEPGPLGPEERPP--PAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPA 3146
Query: 702 A---------------PRNSNLRELPIAPS-HVIEMSSSRCSATPSAQVKPIVSASPPSR 745
A R++ + P + S H E +S + P A + +P
Sbjct: 3147 ANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHL-----LTPSPL 3201
Query: 746 AVAGSRSSQGKTEVK----VKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLR 801
+ G S K E++ P P A E K E+ L E L
Sbjct: 3202 SGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESS------------LVASELPLLI 3249
Query: 802 EEILK--QKELRRQQQAGARKKELLERLAQQQQ-QLYAPPPPAEQ---EEQALSPSPTNG 855
E++L+ +KEL+++QQ A+ + ++ QQQQ L + P PA+ + SPS
Sbjct: 3250 EDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGS 3309
Query: 856 NPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQ 915
L A RQ + L+ Q + + Q PS A + QG + +H Q
Sbjct: 3310 QQQLSLGLAGARQPGLPQPLMPTQPPAHALQQ----RLAPSMAMVSNQGHMLSG-QHGGQ 3364
Query: 916 TRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQ 953
VPQ +QP VL KP P++ P+ ++Q
Sbjct: 3365 AGLVPQQSSQP---VLSQKPMGTMPPSMCMKPQQLAMQ 3399
Score = 44.3 bits (103), Expect = 7e-04
Identities = 153/703 (21%), Positives = 244/703 (34%), Gaps = 136/703 (19%)
Query: 499 PTQSPLPFTQ-PGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFS--------QPGSA 549
P+QSP T+ PG G QP P P G G L + QPG
Sbjct: 3621 PSQSPRLLTKLPGQLLPGHGLQP---------PQGPPGGQAGGLRLTPGGMALPGQPGGP 3671
Query: 550 TTRPFIPPRQP--------FLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQP 601
+ +Q L GP F P + GP L QQ Q
Sbjct: 3672 FLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLA 3731
Query: 602 PPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHV 661
Q Q Q Q Q Q P Q + L P LMP S Q
Sbjct: 3732 QKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQA---LGPKPQGLMPPSSHQGLLVQ 3788
Query: 662 QTA-QPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIE 720
Q + QP M P + + +QQ P A P P +
Sbjct: 3789 QLSPQPPQGPQGMLGPAQVAV-------------LQQQHPGALG-------PQGPHRQVL 3828
Query: 721 MSSSRCSATPSAQVKP-------IVSASPPSRAVAGSR--SSQGKTEVKVKPASPVAQPK 771
M+ SR ++P + +V+A + + S G + ++ S QPK
Sbjct: 3829 MTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPK 3888
Query: 772 EEAKTETEFPDEDEETRLYR---LKIEEQKRLREEI-LKQKELRRQQQAGARKKELLERL 827
A+ ++ +L + L+ ++Q++L+++ L+Q++L++QQQ +++ ++L
Sbjct: 3889 LSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQL 3948
Query: 828 AQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQ 887
QQQQQL +Q+ Q +Q + ++ + NQ ++ + Q
Sbjct: 3949 QQQQQQLQQQQQQQQQQFQ--------------------QQQQQQQMGLLNQSRTLLSPQ 3988
Query: 888 PKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQ-- 945
+ V G K L+H + + +L K + +PAV
Sbjct: 3989 QQQQQQVALG-----PGMPAKPLQHFSSPGALGPT------LLLTGKEQNTVDPAVSSEA 4037
Query: 946 TPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEG 1005
T ++ QG P + T G P +S +++ +
Sbjct: 4038 TEGPSTHQGGPL----AIGTTPESMATEPGEVKPSLSGDSQLLLV--------------- 4078
Query: 1006 QPQRLPQPPEVGPQPARKVTLTRGGLQQPPHL--PAGPHAHSPVPPGIKSIQGIHP---A 1060
QPQ PQP + QP ++ G QQ L AG +H + G S P A
Sbjct: 4079 QPQPQPQPSSLQLQPPLRLP---GQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135
Query: 1061 KKAIMHGRGRG-----VAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSS---STTDA 1112
+ ++ G G + GP P + N KP P + S +GL T
Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195
Query: 1113 QLKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHR 1155
QL++ L V L PQ R + ++ AL Q++ +
Sbjct: 4196 QLRAQLQGV-----LAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
Score = 39.3 bits (90), Expect = 0.022
Identities = 142/700 (20%), Positives = 231/700 (33%), Gaps = 132/700 (18%)
Query: 511 PAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPF- 569
PA QQ QQ L PGP + GS+ P L G Q
Sbjct: 3272 PAQQQQQQQQQ-------HSLLSAPGPAQAMSLPHEGSS----------PSLAGSQQQLS 3314
Query: 570 --LPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPP 627
L QP L PL P PP H QQ+ P H QH P
Sbjct: 3315 LGLAGARQPGLPQPLMPTQPPAH-----ALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVP 3369
Query: 628 QHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTS 687
Q Q LS P MP S +P Q Q ++S
Sbjct: 3370 QQSSQPV-------LSQKPMGTMPPSM-CMKPQQLAMQQQLANSFFPDTDLDKFAAEDII 3421
Query: 688 QNVSKRPMQQMQ--PTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSR 745
++K M ++ ++ P + + + R S PS+ ++ V+A
Sbjct: 3422 DPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQE 3481
Query: 746 AVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEIL 805
AG S QP+ T + + + R Y EE +++L
Sbjct: 3482 RSAGDPS----------------QPRPNPPTFAQGVINEADQRQY----EEWLFHTQQLL 3521
Query: 806 KQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQ 865
+ + ++Q G +K A+Q+ A E + + L
Sbjct: 3522 QMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKL----------------- 3564
Query: 866 VRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQ 925
+ + + ++ Q + Q + +N + N Q Q QQ + + + + + S +Q
Sbjct: 3565 -KLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQ 3623
Query: 926 PLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKV 985
++L P + Q P QG P G++ T G GP +++ +
Sbjct: 3624 S-PRLLTKLPGQLLPGHGLQPP-----QGPPGGQAGGLRLTPGGMALPGQPGGPFLNTAL 3677
Query: 986 ---RVIKLSGGGGE----SDGFF------HPEGQPQRLPQPPEVGPQP-----ARKVTLT 1027
+ + SGG G S GFF G RL Q ++ Q A+K+
Sbjct: 3678 AQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQ 3737
Query: 1028 RGGLQQPPHL--PAGPHAHSPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNK 1085
+ QQ HL PG+++ Q + GP +G + P+
Sbjct: 3738 QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQAL----------------GPKPQGLMPPSS 3781
Query: 1086 -QNLRVVECKPQP-------------CVVSVEGLSSSTTDAQLKSLLMSVGPIQSLQMLP 1131
Q L V + PQP V+ + + + +LM+ + S L
Sbjct: 3782 HQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLA 3841
Query: 1132 QQRKAIAKFKEPAHALAFQQKFHRH---MIDLSHINVALI 1168
QQ + + + QQ+ H+ M LSH+ +L+
Sbjct: 3842 QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLM 3881
Score = 38.9 bits (89), Expect = 0.029
Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 14/118 (11%)
Query: 511 PAFNQQGQQPVFPRERPVRPALQPPGP------VGILHFSQPGSATTRPFIPPRQPFLPG 564
P + + Q + + PA +PP V L Q + PP P P
Sbjct: 4865 PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS 4924
Query: 565 PG----QPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQ 618
P +P + T+P + P+ PLP P+ +P+ P+ +PP + PP+
Sbjct: 4925 PASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPK----PRARPPEEGEDSRPPR 4978
Score = 37.4 bits (85), Expect = 0.084
Identities = 55/218 (25%), Positives = 75/218 (34%), Gaps = 47/218 (21%)
Query: 314 PVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHP-SPPQGMHMPPQLETPRMMM 372
PV P PP P P L +P P Q +QH P + P PP L +
Sbjct: 995 PVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALP----LS 1050
Query: 373 TPPPVTP---------------------QQPKNIHINPHFKGTVVTPVQVPLLPVPSQPR 411
P P++P +P+ + P + +P+ P PS P
Sbjct: 1051 VPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS-PA 1109
Query: 412 PAVGPQR-------------FPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDR 458
PA+ PG P TPG + + P L L + AP P +
Sbjct: 1110 PALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVL-LDPEELAPVTPMEV 1168
Query: 459 DPFFLGVSGEPRFPSHLFLEQRSPPPP--PPPPTLLNS 494
P +G+ P EQ P P P PPTL+ S
Sbjct: 1169 YPECKQTAGQGS-PCE---EQEEPRAPVAPTPPTLIKS 1202
Score = 32.7 bits (73), Expect = 2.1
Identities = 35/123 (28%), Positives = 43/123 (34%), Gaps = 29/123 (23%)
Query: 438 SQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPP---PPPTLLNS 494
SQ L L Q P P + + VS +L + Q S PPP PPP+ L
Sbjct: 4871 SQLDILSLLKQESPAPEPPTQHSYTYNVS-------NLDVRQLSAPPPEEPSPPPSPLAP 4923
Query: 495 SHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPF 554
S P PL E P P +PP P + S P SA +P
Sbjct: 4924 SPASPPTEPLV-------------------ELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 555 IPP 557
P
Sbjct: 4965 ARP 4967
Score = 32.3 bits (72), Expect = 2.7
Identities = 22/88 (25%), Positives = 28/88 (31%), Gaps = 15/88 (17%)
Query: 595 QQPQQQPPPQHQ---------------PPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHH 639
+ P +PP QH PP + P PP P P PP P
Sbjct: 4882 ESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPL 4941
Query: 640 HHLSVPPPPLMPMSQPQFRPHVQTAQPQ 667
VP P + S RP + P+
Sbjct: 4942 AEPPVPSPLPLASSPESARPKPRARPPE 4969
Score = 32.0 bits (71), Expect = 3.5
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 313 PPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMM 372
PP P+ P PPP P P +P P P+ P PS P + P+ P+
Sbjct: 4909 PP--PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS-PLPLASSPESARPKPRA 4965
Query: 373 TPP 375
PP
Sbjct: 4966 RPP 4968
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 105 bits (263), Expect = 2e-22
Identities = 117/390 (30%), Positives = 140/390 (35%), Gaps = 51/390 (13%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQL 365
P P Q PQ PP PP PQ P + QPQ P P P P PPQG + P
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP--PPGKPQGP-PPQGGNKPQG- 91
Query: 366 ETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEF 425
PPP PQ P P +P P P P+ PQ P PP
Sbjct: 92 -------PPPPGKPQGP------PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 138
Query: 426 PQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQD-RDPFFLGVSGEPRFPSHLFLEQ-RSPP 483
PQ GP P ++P P + + PPP D + G+P+ P Q + PP
Sbjct: 139 PQ---GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP 195
Query: 484 PPP-----PPPTLLNSSH-PVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQ---- 533
PPP PPP N P P P P P + + Q P +P P Q
Sbjct: 196 PPPGKPQGPPPQGGNKPQGPPPPGKP---QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252
Query: 534 ---PPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPH 590
PP P G +P + P+ P P PG+P P + P P
Sbjct: 253 PQGPPPPPG-----KPQGPPPQGGNKPQGP--PPPGKPQGPPPQGGSKSRSSRSPPGKPQ 305
Query: 591 QPQPQ---QPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPP 647
P PQ QPQ PPP +P PP PPP PQ PP S P
Sbjct: 306 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR---SARSP 362
Query: 648 PLMPMSQPQFRPHVQTAQPQASSSRMQCPQ 677
P P PQ + P + Q PQ
Sbjct: 363 PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 392
Score = 100 bits (249), Expect = 8e-21
Identities = 119/397 (29%), Positives = 139/397 (35%), Gaps = 79/397 (19%)
Query: 305 RPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQ 364
+P P Q PQ PPPPP PQ P + +PQ P Q P PPQG
Sbjct: 56 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP----PPQGDKSRSP 111
Query: 365 LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPE 424
P PPP QP+ P P P P+ PQ P PP
Sbjct: 112 RSPPGKPQGPPPQGGNQPQG-------------PPPPPGKPQGPPPQGGNKPQG-PPPPG 157
Query: 425 FPQHTPGPVPN---SFSQPPRLPL------QDQWRAPPPPQDRDPFFLGVSGEPRFPSHL 475
PQ P N S PP P +Q + PPPP G+P+ P
Sbjct: 158 KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP----------PGKPQGPPPQ 207
Query: 476 FLEQRSPPPPP-----PPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRP 530
+ PPPP PPP N S +SP P GP Q G QP P P +P
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQ--SARSP-PGKPQGPP-PQGGNQPQGPPPPPGKP 263
Query: 531 ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGP----------GQPFLPTHTQPNLQG 580
PP Q G+ P PP +P P P P P P
Sbjct: 264 QGPPP---------QGGNKPQGP-PPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 581 PLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQ------HQPPPQHPPQHPPQHQ 634
P PPP +PQ PQ PQ PP P PPPQ P PQ PPQ +
Sbjct: 314 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE 373
Query: 635 HHHHHHHLSVPPP----PLMPMSQPQFRPHVQTAQPQ 667
++ PPP P P + P +P PQ
Sbjct: 374 GNNPQ---GPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 407
Score = 100 bits (249), Expect = 8e-21
Identities = 114/363 (31%), Positives = 133/363 (36%), Gaps = 58/363 (15%)
Query: 305 RPALLPTQPPVVPQAPPPPP----PPPQQQPIRSLFQPQPLQPLLPV----QHPHHPSPP 356
+P P Q PQ PPPP PPPQ RS P P +P P P P PP
Sbjct: 77 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPPPQGGNQPQGPPPP 135
Query: 357 QGMHM-PPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVG 415
G PP + PPP PQ P P + P P P+
Sbjct: 136 PGKPQGPPPQGGNKPQGPPPPGKPQGPP-----PQGDNKSRSSRSPPGKPQGPPPQGGNQ 190
Query: 416 PQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQD-RDPFFLGVSGEPRFPSH 474
PQ P PP PQ GP P ++P P + + PPP D + G+P+ P
Sbjct: 191 PQGPPPPPGKPQ---GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 475 LFLEQ-RSPPPPP-----PPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPV 528
Q + PPPPP PPP N P P P GP Q G + R P
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNK----PQGPPPPGKPQGPP-PQGGSKSRSSRSPPG 302
Query: 529 RPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLP---------GPGQPFLPTHTQPNLQ 579
+P PP Q G+ P PP +P P GP P P P
Sbjct: 303 KPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 353
Query: 580 GPLHPPLPPPHQPQ--PQQ----PQQQPPPQHQPPHQPPHQPPPQHQPPPQHP----PQH 629
PP +PQ PQQ PQ PPP P QP P Q Q PP+ P P
Sbjct: 354 SKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 413
Query: 630 PPQ 632
PPQ
Sbjct: 414 PPQ 416
Score = 89.4 bits (220), Expect = 2e-17
Identities = 111/419 (26%), Positives = 141/419 (33%), Gaps = 79/419 (18%)
Query: 364 QLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPP 423
Q E+P ++ P P Q N P P P Q P G + GPP
Sbjct: 25 QEESPSLIAGNPQGAPPQGGN------------KPQGPPSPPGKPQGPPPQGGNQPQGPP 72
Query: 424 EFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPP 483
P GP P ++P P + + PPP D+ G+P+ P Q P
Sbjct: 73 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 132
Query: 484 PPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPG-PVGILH 542
PPPP P P P P P QG P + R + PPG P G
Sbjct: 133 PPPPG----KPQGPPPQGGNKPQGPPPPG-KPQGPPP--QGDNKSRSSRSPPGKPQG--- 182
Query: 543 FSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNL-QGPLHPPLPPPHQPQPQQPQQQP 601
P +P PP P PG+P P N QGP PPP +PQ PQ
Sbjct: 183 --PPPQGGNQPQGPP-----PPPGKPQGPPPQGGNKPQGP-----PPPGKPQGPPPQGDN 230
Query: 602 PPQ--HQPPHQPPHQPP-----PQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQ 654
Q PP +P PP PQ PPP PQ PP + PPPP P
Sbjct: 231 KSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGP 286
Query: 655 PQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIA 714
P PQ S S+ P + Q P+ N + P
Sbjct: 287 P----------PQGGS----------------KSRSSRSPPGKPQGPPPQGGNQPQGPPP 320
Query: 715 PSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEE 773
P + + P P PP + + SRS++ P P P++E
Sbjct: 321 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARS------PPGKPQGPPQQE 373
Score = 85.1 bits (209), Expect = 4e-16
Identities = 99/335 (29%), Positives = 113/335 (33%), Gaps = 87/335 (25%)
Query: 289 GDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQ 348
GD + S+ K P P Q PQ PPPPP PQ P + +P Q
Sbjct: 166 GDNKSRSSRSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPPQGGNKP---------Q 213
Query: 349 HPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPS 408
P P PQG PPQ + PP PQ P
Sbjct: 214 GPPPPGKPQG--PPPQGDNKSQSARSPPGKPQGP-------------------------- 245
Query: 409 QPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE 468
P G + GPP P GP P ++P + PPPP G
Sbjct: 246 ---PPQGGNQPQGPPPPPGKPQGPPPQGGNKP---------QGPPPPGK-------PQGP 286
Query: 469 PRFPSHLFLEQRSPP--PPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER 526
P RSPP P PPP N P P P GP Q G +P P
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP---PPPGKPQGPP-PQGGNKPQGP-PP 341
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586
P +P PP Q GS + PP +P GP P N QGP
Sbjct: 342 PGKPQGPPP---------QGGSKSRSARSPPGKP--QGP-----PQQEGNNPQGP----- 380
Query: 587 PPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQP 621
PPP PQQPQ P Q Q P +PP P P
Sbjct: 381 PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 50.1 bits (118), Expect = 1e-05
Identities = 118/497 (23%), Positives = 145/497 (29%), Gaps = 146/497 (29%)
Query: 581 PLHPPLPP--PHQPQPQ---QPQQQPPPQHQPPHQPPHQP-PPQHQPPPQHPPQHPPQHQ 634
P PP PP P P PQ QPQ PPP +P PP PQ PPP P PPQ
Sbjct: 47 PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106
Query: 635 HHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRP 694
P P +PQ P QPQ PQ + Q P
Sbjct: 107 KSRS---------PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP--P 155
Query: 695 MQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQ 754
+ Q P+ N SR S +P + + PP + G Q
Sbjct: 156 PGKPQGPPPQGDN---------------KSRSSRSPPGKPQ-----GPPPQ---GGNQPQ 192
Query: 755 GKTEVKVKPASPVAQ-------PKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQ 807
G KP P Q P K + P D +++ R
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP------------PG 240
Query: 808 KELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGN-PLLPFPGAQV 866
K Q G Q PPPP + + P P GN P P P +
Sbjct: 241 KPQGPPPQGG--------------NQPQGPPPPPGKPQ---GPPPQGGNKPQGPPPPGKP 283
Query: 867 RQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQP 926
QG + R +R+ P P
Sbjct: 284 ------------------------------------QGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 927 LHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKP--GVKRTVTHRTNSGGGDGPHISSK 984
P +P P P G+PQ P G K G P SK
Sbjct: 308 -------PPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 355
Query: 985 VRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGPHAH 1044
R + G P+G PQ+ P+ P PA G QQP PAG
Sbjct: 356 SRSARSPPG--------KPQGPPQQEGNNPQGPPPPAG------GNPQQPQAPPAGQPQG 401
Query: 1045 SPVPPGIKSIQGIHPAK 1061
P PP QG P++
Sbjct: 402 PPRPP-----QGGRPSR 413
Score = 47.8 bits (112), Expect = 6e-05
Identities = 44/141 (31%), Positives = 53/141 (37%), Gaps = 19/141 (13%)
Query: 286 RGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLL 345
+G Q + R +P P Q PQ PPPPP PQ P + +P
Sbjct: 284 QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP------- 336
Query: 346 PVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLP 405
Q P P PQG PPQ + PP PQ P P +G P
Sbjct: 337 --QGPPPPGKPQG--PPPQGGSKSRSARSPPGKPQGP------PQQEGNNPQGPPPPAGG 386
Query: 406 VPSQPR--PAVGPQRFPGPPE 424
P QP+ PA PQ P PP+
Sbjct: 387 NPQQPQAPPAGQPQGPPRPPQ 407
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 104 bits (260), Expect = 4e-22
Identities = 177/721 (24%), Positives = 250/721 (34%), Gaps = 172/721 (23%)
Query: 208 EEEDDEESGRLRFKTERKEGTIIRL-------------------SDVTRERRNIP----- 243
+EEDD SG+ +T R G++ L D+ RN P
Sbjct: 6 KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAAST 65
Query: 244 -------ETLELSA----EAKAALLEFEERERQ------HKQGRYSSRRG-----GRRGG 281
ET++ SA E ++ L+ +R+R+ + R SS++ R
Sbjct: 66 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 125
Query: 282 PLMCRGVGDQRRESTERGRM--KDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQ 339
P G R + G KD T P + P P + S Q Q
Sbjct: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI-------PSPQDNESDSDSSAQQQ 178
Query: 340 PLQ---PLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVV 396
LQ P L P+P PQL TP + V PQ P+
Sbjct: 179 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN------ 232
Query: 397 TPVQVPLLPVPS---QPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPP 453
Q P PVP Q PA+ PQR P +P P P+ PP PL P
Sbjct: 233 -QPQAPTAPVPHTHIQQAPALHPQRPP--------SPHPPPHPSPHPPLQPLTGSAGQPS 283
Query: 454 PPQDRDP--FFLGVSGEPRFPSHLFLEQRSPPPP-PPPPTLLNSSHPVPTQ--SPLPFTQ 508
P P G G + L+ PP P PP P+ T + P T
Sbjct: 284 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTS 343
Query: 509 ---PGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGP 565
P Q QQP PRE+P+ PP P+ + H P T P P LP P
Sbjct: 344 LQLPASQSALQSQQP--PREQPL-----PPAPLAMPHIKPP---PTTPI-----PQLPAP 388
Query: 566 GQPFLPTHTQPNLQGPLHPPLPPP------------HQPQPQQPQQQPPPQHQP----PH 609
P H ++ LPPP H P P Q PQ QP P
Sbjct: 389 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 448
Query: 610 QPPHQPPPQHQPPPQHPPQHPPQHQHH-------HHHHHLSVPPPPLMPMSQPQFRPHVQ 662
QPP Q+ PPP P HPP H H + PPP+ P + P
Sbjct: 449 QPPGLTQSQNLPPP--PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCP------S 500
Query: 663 TAQPQA---SSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVI 719
T+ P A +S++ C + + P Q++ A ++ E P P
Sbjct: 501 TSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPR-- 558
Query: 720 EMSSSRCSATPSAQVKPIVSASPPSRAVAGSR---------SSQGKTEVKVKP--ASPVA 768
S +P V PS A +R +S +T++ P S +A
Sbjct: 559 -------SPSPEPTV-----VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 606
Query: 769 QPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLA 828
+ +EEA + + K E +++ REE ++KE ++++ ++ ER A
Sbjct: 607 KKREEA--------------IEKAKREAEQKAREEREREKEKEKEREREREREREAERAA 652
Query: 829 Q 829
+
Sbjct: 653 K 653
Score = 88.2 bits (217), Expect = 4e-17
Identities = 161/731 (22%), Positives = 238/731 (32%), Gaps = 139/731 (19%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQH------PH-------- 351
PAL P +PP P P P PP Q S QP P H PH
Sbjct: 250 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 309
Query: 352 -HPSPPQGMHMPPQ--------------------LETPR-----MMMTPPPVTPQQPKNI 385
HP PPQ +PPQ L+ P PP P P +
Sbjct: 310 QHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL 369
Query: 386 HINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPL 445
+ PH K TP +P LP P + P GP F + P P + L
Sbjct: 370 AM-PHIKPPPTTP--IPQLPAPQAHK---HPPHLSGPSPFSMNANLPPPPALKPLSSLST 423
Query: 446 QDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP-PPTLLNSSHPVPTQSPL 504
A PPP P + P P L Q PPPP PPT L+ P P +
Sbjct: 424 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 483
Query: 505 PFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPG 564
PF GP P+ P P P+ P P G PG++ PP
Sbjct: 484 PFVPGGP-------PPITP---PTCPSTSTP-PAG------PGTSAQ----PPCSGAAAS 522
Query: 565 PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQ 624
G ++ G PLP Q + + P+ PP PP P P +P
Sbjct: 523 GG----------SIAGGSSCPLPTV-QIKEEALDDAEEPESPPP--PPRSPSP--EPTVV 567
Query: 625 HPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHN 684
P H Q + H + F P + + ++ +R+ +
Sbjct: 568 DTPSHASQSARFYKHLDRGYNS---CARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 624
Query: 685 TTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPS 744
+ K ++ + R A S E S + ++P S PP
Sbjct: 625 REEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRP--SFEPPP 682
Query: 745 RAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFP-----DEDEETRLYRLK--IEEQ 797
+A G ++ S A+P + T P + + Y +
Sbjct: 683 TTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVD 742
Query: 798 KRLREEILKQKELRRQQQAGARKKELLERL-------AQQQQQLYAPPPPAEQ--EEQAL 848
+RE L+++E+R ++ R++EL ER+ + L+ P E AL
Sbjct: 743 PTIRERELREREIRERE---IRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 799
Query: 849 SPSPTNG-----------NPL----LPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNF 893
+ PT G NPL L G Q+R + + + + + TS+
Sbjct: 800 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP 859
Query: 894 VP-----SSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVL------------PIKPA 936
+ + +Q + + HL Q + Q P+H ++ P P
Sbjct: 860 LARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPG 919
Query: 937 DVEEPAVPQTP 947
+ P + Q P
Sbjct: 920 TLPNPLLGQPP 930
Score = 40.4 bits (93), Expect = 0.010
Identities = 83/414 (20%), Positives = 134/414 (32%), Gaps = 53/414 (12%)
Query: 684 NTTSQNVSKRPMQQMQPTAPRNSNLREL----PIAPSHVIEMSSSRCSATPSAQVK---- 735
+T K+P T+P N ++R P A S S + + +VK
Sbjct: 28 STLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAS 87
Query: 736 -PIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKI 794
P+ S VA +T K +++P ++ E E D +
Sbjct: 88 SPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS--------V 139
Query: 795 EEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTN 854
++ + + Q + + + + QQQ+ PPA Q ++P+P++
Sbjct: 140 NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 199
Query: 855 ---GNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALK 911
G P LP PG + V Q ++ P P++ QQ AL
Sbjct: 200 APPGTPQLPTPGP-----TPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPALH 253
Query: 912 HLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQ----------TPRVASIQGRPQDTKP 961
R P P H L +P+ P P S+Q P P
Sbjct: 254 PQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 312
Query: 962 GVKRTVTHRTNSGGGDGPHISSKVRVI-KLSGGGGESDGFFHPEGQPQRLPQP------P 1014
G + + G P +S S S + P+ P P P
Sbjct: 313 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 372
Query: 1015 EVGPQPARKVTLTRG--GLQQPPHL----PAGPHAHSPVPPGIKSIQGI---HP 1059
+ P P + + PPHL P +A+ P PP +K + + HP
Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
Score = 35.8 bits (81), Expect = 0.25
Identities = 96/418 (22%), Positives = 140/418 (33%), Gaps = 69/418 (16%)
Query: 233 SDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQR 292
S + ++R E + AE KA E ERE++ ++ R R R +
Sbjct: 603 SKLAKKREEAIEKAKREAEQKAR--EEREREKEKEKEREREREREREAERAA------KA 654
Query: 293 RESTERGRMKDH--------RPALLPTQPPVVPQAPPP--PPPPPQQQPIRSLFQPQPLQ 342
S GR+ D RP+ P PP A PP P P + + +P +
Sbjct: 655 SSSAHEGRLSDPQLSGPGHMRPSFEP--PPTTIAAVPPYIGPDTPALRTLSEYARPHVMS 712
Query: 343 PLL---PVQHPHHPSPPQ-GMHMPPQLETPRMM----MTPPPVTPQQPKNIHINPHFK-G 393
P P P +P+ P HMP + + + ++ + + K G
Sbjct: 713 PTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPG 772
Query: 394 TVVTPVQV-PLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAP 452
V P ++ PL P + PP T GP P + P PL+ + A
Sbjct: 773 FEVKPPELDPLHPAANPMEHFARHSALTIPP-----TAGPHPFASFHPGLNPLERERLAL 827
Query: 453 PPPQDRDPFFLGVSGEPRFPSHLFLE----QRSPPPPPPPPTLLNSSHPVP-------TQ 501
PQ R E +P L E +R P L + P
Sbjct: 828 AGPQLRP--------EMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIH 879
Query: 502 SPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFI--PPRQ 559
S L Q P +Q PV P P+ GP + F P P + PP +
Sbjct: 880 SHLHLHQQDP-LHQGSAGPVHPLVDPLTA-----GP-HLARFPYPPGTLPNPLLGQPPHE 932
Query: 560 PFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQ----QQPPPQHQPPHQPPH 613
+ P T +L G + PP+ HQ Q Q Q+ + Q H PH
Sbjct: 933 HEMLR--HPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPH 988
Score = 33.9 bits (76), Expect = 0.93
Identities = 42/168 (25%), Positives = 55/168 (32%), Gaps = 30/168 (17%)
Query: 499 PTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI--LHFSQPGSATTRPFIP 556
PT P PF P N ++ + +RP + P + +H + S T+ P +
Sbjct: 803 PTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LA 861
Query: 557 PRQPFLPGPGQ-------PFLPTHTQPNLQ----GPLHP--------------PLPPPHQ 591
Q F P L H Q L GP+HP P PP
Sbjct: 862 RLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTL 921
Query: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHH 639
P P Q PP +H+ P P P PP HQ H
Sbjct: 922 PNPLLGQ--PPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMH 967
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 104 bits (260), Expect = 4e-22
Identities = 177/721 (24%), Positives = 250/721 (34%), Gaps = 172/721 (23%)
Query: 208 EEEDDEESGRLRFKTERKEGTIIRL-------------------SDVTRERRNIP----- 243
+EEDD SG+ +T R G++ L D+ RN P
Sbjct: 560 KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAAST 619
Query: 244 -------ETLELSA----EAKAALLEFEERERQ------HKQGRYSSRRG-----GRRGG 281
ET++ SA E ++ L+ +R+R+ + R SS++ R
Sbjct: 620 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 679
Query: 282 PLMCRGVGDQRRESTERGRM--KDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQ 339
P G R + G KD T P + P P + S Q Q
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI-------PSPQDNESDSDSSAQQQ 732
Query: 340 PLQ---PLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVV 396
LQ P L P+P PQL TP + V PQ P+
Sbjct: 733 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN------ 786
Query: 397 TPVQVPLLPVPS---QPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPP 453
Q P PVP Q PA+ PQR P +P P P+ PP PL P
Sbjct: 787 -QPQAPTAPVPHTHIQQAPALHPQRPP--------SPHPPPHPSPHPPLQPLTGSAGQPS 837
Query: 454 PPQDRDP--FFLGVSGEPRFPSHLFLEQRSPPPP-PPPPTLLNSSHPVPTQ--SPLPFTQ 508
P P G G + L+ PP P PP P+ T + P T
Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTS 897
Query: 509 ---PGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGP 565
P Q QQP PRE+P+ PP P+ + H P T P P LP P
Sbjct: 898 LQLPASQSALQSQQP--PREQPL-----PPAPLAMPHIKPP---PTTPI-----PQLPAP 942
Query: 566 GQPFLPTHTQPNLQGPLHPPLPPP------------HQPQPQQPQQQPPPQHQP----PH 609
P H ++ LPPP H P P Q PQ QP P
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 610 QPPHQPPPQHQPPPQHPPQHPPQHQHH-------HHHHHLSVPPPPLMPMSQPQFRPHVQ 662
QPP Q+ PPP P HPP H H + PPP+ P + P
Sbjct: 1003 QPPGLTQSQNLPPP--PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCP------S 1054
Query: 663 TAQPQA---SSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVI 719
T+ P A +S++ C + + P Q++ A ++ E P P
Sbjct: 1055 TSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPR-- 1112
Query: 720 EMSSSRCSATPSAQVKPIVSASPPSRAVAGSR---------SSQGKTEVKVKP--ASPVA 768
S +P V PS A +R +S +T++ P S +A
Sbjct: 1113 -------SPSPEPTV-----VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 1160
Query: 769 QPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLA 828
+ +EEA + + K E +++ REE ++KE ++++ ++ ER A
Sbjct: 1161 KKREEA--------------IEKAKREAEQKAREEREREKEKEKEREREREREREAERAA 1206
Query: 829 Q 829
+
Sbjct: 1207 K 1207
Score = 88.2 bits (217), Expect = 4e-17
Identities = 161/731 (22%), Positives = 238/731 (32%), Gaps = 139/731 (19%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQH------PH-------- 351
PAL P +PP P P P PP Q S QP P H PH
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 863
Query: 352 -HPSPPQGMHMPPQ--------------------LETPR-----MMMTPPPVTPQQPKNI 385
HP PPQ +PPQ L+ P PP P P +
Sbjct: 864 QHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL 923
Query: 386 HINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPL 445
+ PH K TP +P LP P + P GP F + P P + L
Sbjct: 924 AM-PHIKPPPTTP--IPQLPAPQAHK---HPPHLSGPSPFSMNANLPPPPALKPLSSLST 977
Query: 446 QDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP-PPTLLNSSHPVPTQSPL 504
A PPP P + P P L Q PPPP PPT L+ P P +
Sbjct: 978 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 1037
Query: 505 PFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPG 564
PF GP P+ P P P+ P P G PG++ PP
Sbjct: 1038 PFVPGGP-------PPITP---PTCPSTSTP-PAG------PGTSAQ----PPCSGAAAS 1076
Query: 565 PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQ 624
G ++ G PLP Q + + P+ PP PP P P +P
Sbjct: 1077 GG----------SIAGGSSCPLPTV-QIKEEALDDAEEPESPPP--PPRSPSP--EPTVV 1121
Query: 625 HPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHN 684
P H Q + H + F P + + ++ +R+ +
Sbjct: 1122 DTPSHASQSARFYKHLDRGYNS---CARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 1178
Query: 685 TTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPS 744
+ K ++ + R A S E S + ++P S PP
Sbjct: 1179 REEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRP--SFEPPP 1236
Query: 745 RAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFP-----DEDEETRLYRLK--IEEQ 797
+A G ++ S A+P + T P + + Y +
Sbjct: 1237 TTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVD 1296
Query: 798 KRLREEILKQKELRRQQQAGARKKELLERL-------AQQQQQLYAPPPPAEQ--EEQAL 848
+RE L+++E+R ++ R++EL ER+ + L+ P E AL
Sbjct: 1297 PTIRERELREREIRERE---IRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 1353
Query: 849 SPSPTNG-----------NPL----LPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNF 893
+ PT G NPL L G Q+R + + + + + TS+
Sbjct: 1354 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP 1413
Query: 894 VP-----SSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVL------------PIKPA 936
+ + +Q + + HL Q + Q P+H ++ P P
Sbjct: 1414 LARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPG 1473
Query: 937 DVEEPAVPQTP 947
+ P + Q P
Sbjct: 1474 TLPNPLLGQPP 1484
Score = 44.7 bits (104), Expect = 5e-04
Identities = 92/454 (20%), Positives = 149/454 (32%), Gaps = 60/454 (13%)
Query: 644 VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAP 703
V PPP M F+P + + M+ + +G +T K+P T+P
Sbjct: 549 VDPPPFM------FKPVKEEDDGLSGKHSMRTRRSRGSM-STLRSGRKKQPASPDGRTSP 601
Query: 704 RNSNLREL----PIAPSHVIEMSSSRCSATPSAQVK-----PIVSASPPSRAVAGSRSSQ 754
N ++R P A S S + + +VK P+ S VA
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661
Query: 755 GKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQ 814
+T K +++P ++ E E D + ++ + + Q
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRS--------VNDEGSSDPKDIDQDNRSTSP 713
Query: 815 QAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTN---GNPLLPFPGAQVRQNVK 871
+ + + + QQQ+ PPA Q ++P+P++ G P LP PG
Sbjct: 714 SIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TP 768
Query: 872 NRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVL 931
+ V Q ++ P P++ QQ AL R P P H L
Sbjct: 769 SATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPL 826
Query: 932 PIKPADVEEPAVPQ----------TPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHI 981
+P+ P P S+Q P PG + + G P
Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 886
Query: 982 SSKVRVI-KLSGGGGESDGFFHPEGQPQRLPQP------PEVGPQPARKVTLTRG--GLQ 1032
+S S S + P+ P P P + P P + +
Sbjct: 887 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 946
Query: 1033 QPPHL----PAGPHAHSPVPPGIKSIQGI---HP 1059
PPHL P +A+ P PP +K + + HP
Sbjct: 947 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Score = 35.8 bits (81), Expect = 0.25
Identities = 96/418 (22%), Positives = 140/418 (33%), Gaps = 69/418 (16%)
Query: 233 SDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQR 292
S + ++R E + AE KA E ERE++ ++ R R R +
Sbjct: 1157 SKLAKKREEAIEKAKREAEQKAR--EEREREKEKEKEREREREREREAERAA------KA 1208
Query: 293 RESTERGRMKDH--------RPALLPTQPPVVPQAPPP--PPPPPQQQPIRSLFQPQPLQ 342
S GR+ D RP+ P PP A PP P P + + +P +
Sbjct: 1209 SSSAHEGRLSDPQLSGPGHMRPSFEP--PPTTIAAVPPYIGPDTPALRTLSEYARPHVMS 1266
Query: 343 PLL---PVQHPHHPSPPQ-GMHMPPQLETPRMM----MTPPPVTPQQPKNIHINPHFK-G 393
P P P +P+ P HMP + + + ++ + + K G
Sbjct: 1267 PTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPG 1326
Query: 394 TVVTPVQV-PLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAP 452
V P ++ PL P + PP T GP P + P PL+ + A
Sbjct: 1327 FEVKPPELDPLHPAANPMEHFARHSALTIPP-----TAGPHPFASFHPGLNPLERERLAL 1381
Query: 453 PPPQDRDPFFLGVSGEPRFPSHLFLE----QRSPPPPPPPPTLLNSSHPVP-------TQ 501
PQ R E +P L E +R P L + P
Sbjct: 1382 AGPQLRP--------EMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIH 1433
Query: 502 SPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFI--PPRQ 559
S L Q P +Q PV P P+ GP + F P P + PP +
Sbjct: 1434 SHLHLHQQDP-LHQGSAGPVHPLVDPLTA-----GP-HLARFPYPPGTLPNPLLGQPPHE 1486
Query: 560 PFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQ----QQPPPQHQPPHQPPH 613
+ P T +L G + PP+ HQ Q Q Q+ + Q H PH
Sbjct: 1487 HEMLR--HPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPH 1542
Score = 33.9 bits (76), Expect = 0.93
Identities = 42/168 (25%), Positives = 55/168 (32%), Gaps = 30/168 (17%)
Query: 499 PTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI--LHFSQPGSATTRPFIP 556
PT P PF P N ++ + +RP + P + +H + S T+ P +
Sbjct: 1357 PTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LA 1415
Query: 557 PRQPFLPGPGQ-------PFLPTHTQPNLQ----GPLHP--------------PLPPPHQ 591
Q F P L H Q L GP+HP P PP
Sbjct: 1416 RLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTL 1475
Query: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHH 639
P P Q PP +H+ P P P PP HQ H
Sbjct: 1476 PNPLLGQ--PPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMH 1521
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 104 bits (260), Expect = 4e-22
Identities = 177/721 (24%), Positives = 250/721 (34%), Gaps = 172/721 (23%)
Query: 208 EEEDDEESGRLRFKTERKEGTIIRL-------------------SDVTRERRNIP----- 243
+EEDD SG+ +T R G++ L D+ RN P
Sbjct: 560 KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAAST 619
Query: 244 -------ETLELSA----EAKAALLEFEERERQ------HKQGRYSSRRG-----GRRGG 281
ET++ SA E ++ L+ +R+R+ + R SS++ R
Sbjct: 620 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 679
Query: 282 PLMCRGVGDQRRESTERGRM--KDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQ 339
P G R + G KD T P + P P + S Q Q
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI-------PSPQDNESDSDSSAQQQ 732
Query: 340 PLQ---PLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVV 396
LQ P L P+P PQL TP + V PQ P+
Sbjct: 733 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN------ 786
Query: 397 TPVQVPLLPVPS---QPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPP 453
Q P PVP Q PA+ PQR P +P P P+ PP PL P
Sbjct: 787 -QPQAPTAPVPHTHIQQAPALHPQRPP--------SPHPPPHPSPHPPLQPLTGSAGQPS 837
Query: 454 PPQDRDP--FFLGVSGEPRFPSHLFLEQRSPPPP-PPPPTLLNSSHPVPTQ--SPLPFTQ 508
P P G G + L+ PP P PP P+ T + P T
Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTS 897
Query: 509 ---PGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGP 565
P Q QQP PRE+P+ PP P+ + H P T P P LP P
Sbjct: 898 LQLPASQSALQSQQP--PREQPL-----PPAPLAMPHIKPP---PTTPI-----PQLPAP 942
Query: 566 GQPFLPTHTQPNLQGPLHPPLPPP------------HQPQPQQPQQQPPPQHQP----PH 609
P H ++ LPPP H P P Q PQ QP P
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 610 QPPHQPPPQHQPPPQHPPQHPPQHQHH-------HHHHHLSVPPPPLMPMSQPQFRPHVQ 662
QPP Q+ PPP P HPP H H + PPP+ P + P
Sbjct: 1003 QPPGLTQSQNLPPP--PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCP------S 1054
Query: 663 TAQPQA---SSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVI 719
T+ P A +S++ C + + P Q++ A ++ E P P
Sbjct: 1055 TSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPR-- 1112
Query: 720 EMSSSRCSATPSAQVKPIVSASPPSRAVAGSR---------SSQGKTEVKVKP--ASPVA 768
S +P V PS A +R +S +T++ P S +A
Sbjct: 1113 -------SPSPEPTV-----VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 1160
Query: 769 QPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLA 828
+ +EEA + + K E +++ REE ++KE ++++ ++ ER A
Sbjct: 1161 KKREEA--------------IEKAKREAEQKAREEREREKEKEKEREREREREREAERAA 1206
Query: 829 Q 829
+
Sbjct: 1207 K 1207
Score = 88.2 bits (217), Expect = 4e-17
Identities = 161/731 (22%), Positives = 238/731 (32%), Gaps = 139/731 (19%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQH------PH-------- 351
PAL P +PP P P P PP Q S QP P H PH
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 863
Query: 352 -HPSPPQGMHMPPQ--------------------LETPR-----MMMTPPPVTPQQPKNI 385
HP PPQ +PPQ L+ P PP P P +
Sbjct: 864 QHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL 923
Query: 386 HINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPL 445
+ PH K TP +P LP P + P GP F + P P + L
Sbjct: 924 AM-PHIKPPPTTP--IPQLPAPQAHK---HPPHLSGPSPFSMNANLPPPPALKPLSSLST 977
Query: 446 QDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP-PPTLLNSSHPVPTQSPL 504
A PPP P + P P L Q PPPP PPT L+ P P +
Sbjct: 978 HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH 1037
Query: 505 PFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPG 564
PF GP P+ P P P+ P P G PG++ PP
Sbjct: 1038 PFVPGGP-------PPITP---PTCPSTSTP-PAG------PGTSAQ----PPCSGAAAS 1076
Query: 565 PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQ 624
G ++ G PLP Q + + P+ PP PP P P +P
Sbjct: 1077 GG----------SIAGGSSCPLPTV-QIKEEALDDAEEPESPPP--PPRSPSP--EPTVV 1121
Query: 625 HPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHN 684
P H Q + H + F P + + ++ +R+ +
Sbjct: 1122 DTPSHASQSARFYKHLDRGYNS---CARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKA 1178
Query: 685 TTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPS 744
+ K ++ + R A S E S + ++P S PP
Sbjct: 1179 REEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRP--SFEPPP 1236
Query: 745 RAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFP-----DEDEETRLYRLK--IEEQ 797
+A G ++ S A+P + T P + + Y +
Sbjct: 1237 TTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVD 1296
Query: 798 KRLREEILKQKELRRQQQAGARKKELLERL-------AQQQQQLYAPPPPAEQ--EEQAL 848
+RE L+++E+R ++ R++EL ER+ + L+ P E AL
Sbjct: 1297 PTIRERELREREIRERE---IRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSAL 1353
Query: 849 SPSPTNG-----------NPL----LPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNF 893
+ PT G NPL L G Q+R + + + + + TS+
Sbjct: 1354 TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP 1413
Query: 894 VP-----SSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVL------------PIKPA 936
+ + +Q + + HL Q + Q P+H ++ P P
Sbjct: 1414 LARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPG 1473
Query: 937 DVEEPAVPQTP 947
+ P + Q P
Sbjct: 1474 TLPNPLLGQPP 1484
Score = 44.7 bits (104), Expect = 5e-04
Identities = 92/454 (20%), Positives = 149/454 (32%), Gaps = 60/454 (13%)
Query: 644 VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAP 703
V PPP M F+P + + M+ + +G +T K+P T+P
Sbjct: 549 VDPPPFM------FKPVKEEDDGLSGKHSMRTRRSRGSM-STLRSGRKKQPASPDGRTSP 601
Query: 704 RNSNLREL----PIAPSHVIEMSSSRCSATPSAQVK-----PIVSASPPSRAVAGSRSSQ 754
N ++R P A S S + + +VK P+ S VA
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661
Query: 755 GKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQ 814
+T K +++P ++ E E D + ++ + + Q
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRS--------VNDEGSSDPKDIDQDNRSTSP 713
Query: 815 QAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTN---GNPLLPFPGAQVRQNVK 871
+ + + + QQQ+ PPA Q ++P+P++ G P LP PG
Sbjct: 714 SIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TP 768
Query: 872 NRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVL 931
+ V Q ++ P P++ QQ AL R P P H L
Sbjct: 769 SATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPL 826
Query: 932 PIKPADVEEPAVPQ----------TPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHI 981
+P+ P P S+Q P PG + + G P
Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 886
Query: 982 SSKVRVI-KLSGGGGESDGFFHPEGQPQRLPQP------PEVGPQPARKVTLTRG--GLQ 1032
+S S S + P+ P P P + P P + +
Sbjct: 887 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 946
Query: 1033 QPPHL----PAGPHAHSPVPPGIKSIQGI---HP 1059
PPHL P +A+ P PP +K + + HP
Sbjct: 947 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Score = 35.8 bits (81), Expect = 0.25
Identities = 96/418 (22%), Positives = 140/418 (33%), Gaps = 69/418 (16%)
Query: 233 SDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQR 292
S + ++R E + AE KA E ERE++ ++ R R R +
Sbjct: 1157 SKLAKKREEAIEKAKREAEQKAR--EEREREKEKEKEREREREREREAERAA------KA 1208
Query: 293 RESTERGRMKDH--------RPALLPTQPPVVPQAPPP--PPPPPQQQPIRSLFQPQPLQ 342
S GR+ D RP+ P PP A PP P P + + +P +
Sbjct: 1209 SSSAHEGRLSDPQLSGPGHMRPSFEP--PPTTIAAVPPYIGPDTPALRTLSEYARPHVMS 1266
Query: 343 PLL---PVQHPHHPSPPQ-GMHMPPQLETPRMM----MTPPPVTPQQPKNIHINPHFK-G 393
P P P +P+ P HMP + + + ++ + + K G
Sbjct: 1267 PTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPG 1326
Query: 394 TVVTPVQV-PLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAP 452
V P ++ PL P + PP T GP P + P PL+ + A
Sbjct: 1327 FEVKPPELDPLHPAANPMEHFARHSALTIPP-----TAGPHPFASFHPGLNPLERERLAL 1381
Query: 453 PPPQDRDPFFLGVSGEPRFPSHLFLE----QRSPPPPPPPPTLLNSSHPVP-------TQ 501
PQ R E +P L E +R P L + P
Sbjct: 1382 AGPQLRP--------EMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIH 1433
Query: 502 SPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFI--PPRQ 559
S L Q P +Q PV P P+ GP + F P P + PP +
Sbjct: 1434 SHLHLHQQDP-LHQGSAGPVHPLVDPLTA-----GP-HLARFPYPPGTLPNPLLGQPPHE 1486
Query: 560 PFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQ----QQPPPQHQPPHQPPH 613
+ P T +L G + PP+ HQ Q Q Q+ + Q H PH
Sbjct: 1487 HEMLR--HPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPH 1542
Score = 33.9 bits (76), Expect = 0.93
Identities = 42/168 (25%), Positives = 55/168 (32%), Gaps = 30/168 (17%)
Query: 499 PTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI--LHFSQPGSATTRPFIP 556
PT P PF P N ++ + +RP + P + +H + S T+ P +
Sbjct: 1357 PTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LA 1415
Query: 557 PRQPFLPGPGQ-------PFLPTHTQPNLQ----GPLHP--------------PLPPPHQ 591
Q F P L H Q L GP+HP P PP
Sbjct: 1416 RLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTL 1475
Query: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHH 639
P P Q PP +H+ P P P PP HQ H
Sbjct: 1476 PNPLLGQ--PPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMH 1521
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 101 bits (252), Expect = 4e-21
Identities = 183/786 (23%), Positives = 241/786 (30%), Gaps = 139/786 (17%)
Query: 306 PALLPTQP---PVVPQ---APPPP---PPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPP 356
PA P P P P AP PP PP P+ P + P P + +PP
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV--------TPP 1017
Query: 357 QGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGP 416
P P+ TPP TP PK P P P + P P GP
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGS------PAATPLPKGAPTTPAATLPSPKGGP 1071
Query: 417 QR--FPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSH 474
G P P TP P P P AP PP P G P
Sbjct: 1072 ATPSLKGAPTPPAATP-PSPKGGPATP-----SPKGAPMPPAATPPSPKGGLATPPHKGA 1125
Query: 475 LFLEQRSPPPP------PPP---PTLLNSSHPVPT---QSPLPFTQPG-----PAFNQQG 517
+PP P PPP PT ++ P P +P P P P + G
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 518 QQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQP----FLPGP-GQPFLPT 572
P+ P PA PP P G L P A T P P P P P G P P
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245
Query: 573 HTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQ--PPPQHQPPPQ---HPP 627
T P+ +G P PP + P P PP PPH+ P P PP P
Sbjct: 1246 ATPPSPKG---GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 628 QHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTS 687
PP+ P PP P+ P + + + P +G T
Sbjct: 1303 TSPPK----------GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG-----TP 1347
Query: 688 QNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAV 747
+ P + PT P + +E P P +ATPS + P ++ P R
Sbjct: 1348 TLPATTPSSKGGPTTPSS---KEGPTPP-----------AATPSHKGGPAMTPPSPKRGP 1393
Query: 748 AGSRSSQGKTEVKVKPASPVAQPKEEAKTE-TEFPDEDEETRLYRLKIEEQKRLREEILK 806
A T V P SP P E P + + L +
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD--------------LTPPAVT 1439
Query: 807 QKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNP-LLPFPGAQ 865
L++ A K ++ L A PP+ +E A T+ +P P A
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 866 VRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQ 925
+ ++ + + + P++ + + A K +P + T
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE----ALIPPAMTV 1555
Query: 926 PLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKV 985
P K P P E PA P + +S VT T G +
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASS------------PPAVTPSTYKGAPSPKELLIPP 1603
Query: 986 RVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGPHA-- 1043
V S P+ P PP V P K T P P P +
Sbjct: 1604 AVTSPS---------------PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648
Query: 1044 HSPVPP 1049
SP P
Sbjct: 1649 DSPTSP 1654
Score = 101 bits (252), Expect = 4e-21
Identities = 165/717 (23%), Positives = 238/717 (33%), Gaps = 94/717 (13%)
Query: 298 RGRMKDHRPALLPTQPPVVPQAPP--PPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSP 355
+G + P PT P P +P P PPP+ P P L+ L PH +P
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-PHKGAP 1287
Query: 356 PQGMHMPPQ------LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQ 409
+ PP P+ TPP TP PK P KG P P P +
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Query: 410 PRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRA-PPPPQDRDPFFLGVSGE 468
PA P G P P GP P P P A PP R P G+
Sbjct: 1348 TLPATTPSS-KGGPTTPSSKEGPTP-----PAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401
Query: 469 PRFPSHLFLEQRSPPPPP---------------PPPTLLNSSHPVPTQSPLPFTQPGPAF 513
P P+ + L + P P PP S P S + GPA
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA---PKGGPAT 1458
Query: 514 NQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPG--PGQPFLP 571
P P P P +PP P + S P A P P P LP P P
Sbjct: 1459 PSSKGDPTLPAVTPPSPK-EPPAPKQVATSSSPKKAPATP-APMGAPTLPAVIPSSPKEV 1516
Query: 572 THTQPNLQGPLHP--PLPPPHQPQPQQPQQQ--PPPQHQP-PHQPPHQPPPQHQP--PPQ 624
T + + P+ P L P P++ PP P P + P P P+ P P
Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS 1576
Query: 625 HPPQHPP-----QHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQ 679
PP ++ L +PP P P+ P P + P +
Sbjct: 1577 KEASSPPAVTPSTYKGAPSPKELLIPPAVTSP--SPKEAPTPPAVTPPSPEKGPATPAPK 1634
Query: 680 GLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVS 739
G TS V+ ++ PT+P + + P + + + P+A + +V+
Sbjct: 1635 G---TPTSPPVTPSSLKD-SPTSPASVTCKMGATVPQASKGLPAKK---GPTALKEVLVA 1687
Query: 740 ASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKR 799
+P S + + + +G K SP P AK ++ P + + + ++
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP----LSTVAPAPLLPVQK 1743
Query: 800 LREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLL 859
+ K K+ + E P E + +PSP PL
Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803
Query: 860 PFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTV 919
P P + + PK F+PSS + + K L + +
Sbjct: 1804 PSP--------------------VPTLPPK-QQFLPSSPGLVLESPS-KPLAPADEDELL 1841
Query: 920 PQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGG 976
P +P+ +P + V P TP+ A I P T P K+ VT + N G G
Sbjct: 1842 PLIPPEPISGGVPFQSVLVNMP----TPKSAGI---PVPT-PSAKQPVT-KNNKGSG 1889
Score = 73.9 bits (180), Expect = 8e-13
Identities = 170/757 (22%), Positives = 235/757 (31%), Gaps = 146/757 (19%)
Query: 351 HHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP 410
H P+PP +P+ TP VTP PK G + P + P V + P
Sbjct: 854 HSPTPP----------SPKGAPTPSAVTPLSPK---------GVTLPPKETPTPSVVNLP 894
Query: 411 RPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPR 470
P GP P P + P + + S P + RA P P+ G P
Sbjct: 895 FPKEGPAT-PAPKQAPA-----LSMTSSSPKKA------RATPAPK----------GIPA 932
Query: 471 FPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLP--FTQPGPAFNQQGQQPVFPRERPV 528
PS +PP PP + P P +P P T P P + G P+ P
Sbjct: 933 SPSPKGAP--TPPAATPPSPKGGPATPSPKWAPTPPAATPPSP---KGGPATPSPKGAPT 987
Query: 529 RPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPF------LPTHTQPNLQG-P 581
PA PP P G P A T P + P P PF P T P+ +G P
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 582 LHPPLP-------------PPHQPQPQQPQQQPPPQHQPPHQP---PHQPPPQHQP-PPQ 624
PLP P P + P P P P P P P+ P PP
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107
Query: 625 HPPQHP------PQHQHHHHHHHLSVPPPPL--MPMSQPQFRPHVQTAQPQASSSRMQCP 676
P P P H+ + PP P + P+ P A P + + P
Sbjct: 1108 ATPPSPKGGLATPPHK-GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166
Query: 677 QRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKP 736
+G TT P + +P+ + P P+ S ATPS + P
Sbjct: 1167 PPKGA--PTTPAATPPSPKGGLATPSPKGA-----PTTPA-ATPPSPKGGLATPSPKGAP 1218
Query: 737 IVSASPPSRAVAGSRSSQGK---TEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLK 793
A+ P G + K T P SP P P L
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL---- 1274
Query: 794 IEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPT 853
+ L GA ++ + + +PP A A PSP
Sbjct: 1275 -------------KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP- 1320
Query: 854 NGNPLLPFP-GAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSS--------ANMQYQG 904
G+P P P GA V + + K PSS A ++G
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 905 QQMKALKHLRQTRTVPQSQTQPLH-KVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGV 963
++ +P + P V+P+ P + PA P T A+ + T P V
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK--KAPATPVTREGAATPSKGDLTPPAV 1438
Query: 964 KRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARK 1023
P K GG + P P P+ P P +
Sbjct: 1439 T--------------PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 1024 VTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPA 1060
T + P PA +P P G ++ + P+
Sbjct: 1485 ATSS-----SPKKAPA-----TPAPMGAPTLPAVIPS 1511
Score = 70.9 bits (172), Expect = 7e-12
Identities = 125/575 (21%), Positives = 202/575 (35%), Gaps = 79/575 (13%)
Query: 310 PTQPPVVPQAPPPPPPPPQQQ-----PIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQ 364
PT P V+P +P P P + P + P + P+ + P +P G P
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461
Query: 365 LETPRM-MMTPP-PVTPQQPKNIHINPHFKGTVVTPVQV--PLLP--VPSQPR--PAVGP 416
P + +TPP P P PK + + K TP + P LP +PS P+ PA
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 417 QR----FPGPPEFPQHTPGPV-PNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRF 471
R P + TP + P PP + + + P P ++ P
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA--------PAT 1573
Query: 472 PSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPA 531
PS ++ S PP P T + P P T P P +E P PA
Sbjct: 1574 PSS---KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP------------KEAPTPPA 1618
Query: 532 LQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQ 591
+ PP P P T P + P P P T LP
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSS-LKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677
Query: 592 PQP-QQPQQQPPPQHQPPHQPPHQPPPQ-HQPPPQHPPQHPPQHQHHHHHHHLS-VPPPP 648
P ++ P P+ P P + PQ + PP P + LS V P P
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 649 LMPMSQPQFR----------PHVQTAQPQASSSR-MQCPQRQGLRHNTTSQNVSKRPMQQ 697
L+P+ + + P A P++ +S + + + S +VS P
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797
Query: 698 MQ--------PTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASP-----PS 744
+ PT P LP +P V+E S + ++ P++ P P
Sbjct: 1798 VSLPLAPSPVPTLPPKQQF--LPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 745 RAVAGSRSSQGKTEVKVKPAS---PVAQPKEEAKTETE----FPDEDEETRLYRLKIEEQ 797
++V + + + V S PV + + + TE++ P+ +E+ + Q
Sbjct: 1856 QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ 1915
Query: 798 KRLREEILKQKELRRQQQAGARK-KELLERLAQQQ 831
EI ++ + +Q +K ++ + +L +Q
Sbjct: 1916 LAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQ 1950
Score = 35.4 bits (80), Expect = 0.32
Identities = 61/253 (24%), Positives = 84/253 (33%), Gaps = 73/253 (28%)
Query: 317 PQAPPPPPPPPQQQPIRSLFQPQPLQ-----PLLPVQHPHHPSPPQGMHMP----PQLET 367
P PPP P PQQ P+ + Q P P++ P P G +P P+ T
Sbjct: 43 PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP-FPQSSSGTALPLGTAPEAPT 101
Query: 368 PRMMMTPPPVTPQQ--------------------------------------PKNIHINP 389
+ PP++P P N+ +P
Sbjct: 102 FLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP 161
Query: 390 HF-----KGTVVTPVQVPLLP---------VPSQPRPAVGPQRFPGPP----EFPQHTPG 431
G+V+T + P+ P VPS+ P P+ P PP P H
Sbjct: 162 PSVAVAESGSVIT-LSAPIAPSEPKTNLNKVPSEVVP--NPKGTPSPPCIVSTVPYHCVT 218
Query: 432 PVPNSFSQPPRLP--LQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPP 489
P+ + S LP A PQ +D V P+ P L L + P PP
Sbjct: 219 PMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSL--KGPVSPPAAL 276
Query: 490 TLLNSSHPVPTQS 502
+L S PV T S
Sbjct: 277 SLSTQSLPVVTSS 289
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 99.4 bits (246), Expect = 2e-20
Identities = 139/519 (26%), Positives = 173/519 (33%), Gaps = 111/519 (21%)
Query: 314 PVVPQAPPPPPPPPQQQPI-RSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMM 372
PV+ P P PP P+ L QPQ QP P P+P PPQ TP+
Sbjct: 617 PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP------PQAPTPQAA--APPQATTPQ--- 665
Query: 373 TPPPVTPQQPKNIHIN--PHFKGTVVTPVQVPLLPVP----SQPRPAVGPQRFPGPPEFP 426
P P P+ I + P T + + +P QP A GP
Sbjct: 666 -PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP---------- 714
Query: 427 QHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPP 486
H P S PP P QD P P G P+ P Q SP P P
Sbjct: 715 -HLSVPASVIVSAPP--PAQD-------PAPATPVAKGAGLGPQAPD----SQASPAPAP 760
Query: 487 PPPTLLNSSHPVPTQSP-LPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQ 545
P P P+ SP LP P G P P P RP +PP S+
Sbjct: 761 QIPAAAPLKGPGPSSSPSLPHQAP------LGDSPHLPSPHPTRPPSRPP--------SR 806
Query: 546 PGSATTRPFIPPRQPFLPGPGQPFLP---------------THTQPNLQGPLHPPLPPPH 590
P S + P PP P P P LP ++ P GP PPL P
Sbjct: 807 PQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS 866
Query: 591 QPQPQQPQQQPPPQHQPPHQP--------------PHQPPPQHQ---PPPQHPPQHPPQH 633
QP P+ P PP H PP P P Q PP Q P + P
Sbjct: 867 QP-PEGP--LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
Query: 634 QHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRM-QCPQRQGLRHNTTSQNVSK 692
H + PPPP Q P QP+A R Q P L++ +
Sbjct: 924 PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
Query: 693 RPMQQMQP-TAPRNSNL------RELPIAPSHVIEMSSSRCSATP---SAQVKPIVSASP 742
+ + P T+P S L P APSH + + P A+ K S P
Sbjct: 984 QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLP 1043
Query: 743 PSRAVAGSRSSQGK-------TEVKVKPASPVAQPKEEA 774
+ S GK +++ P QP +EA
Sbjct: 1044 TLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEA 1082
Score = 85.1 bits (209), Expect = 4e-16
Identities = 146/627 (23%), Positives = 207/627 (33%), Gaps = 85/627 (13%)
Query: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP-----HHPSPPQGMHMPPQ 364
P P +P A P P P P P P LP HP PS PQ + PP
Sbjct: 756 PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP- 814
Query: 365 LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFP--GP 422
P + PPP P I + + G V P P P P+P + PQ P GP
Sbjct: 815 -SEPPLHPCPPPQAPPTLPGIFVIQNQLG-VPPPASNPAPTAPGPPQPPLRPQSQPPEGP 872
Query: 423 PEFPQHTPGPVPNSFSQPPRLPLQDQWRAP-PPPQDRDPFFLGVSGEPRFPS-----HLF 476
H P P+S S + R P P P D F G + P+ HL
Sbjct: 873 LPPAPHLP---PSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLV 929
Query: 477 LEQRSPPPPPP---------------PPTLLNSSHPVPTQSPL----------------- 504
E +PPPPPP P LL H VP+ L
Sbjct: 930 PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
Query: 505 -PFTQPGPAFNQQGQ----QPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQ 559
P T P + GQ P P P + G +L A+ P + +
Sbjct: 990 GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAK 1049
Query: 560 PFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQ-----PPHQP--P 612
GPG+P + L G PP QP + + +HQ P ++ P
Sbjct: 1050 AASSGPGKP-SGLQYESKLSG---LKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFP 1105
Query: 613 HQPPPQHQPPPQHPPQH--PPQHQHHHHHHHLSVPPPPLMPMSQPQFRPH----VQTAQP 666
H+ P H Q P +H L+ +Q + ++ ++
Sbjct: 1106 SFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRR 1165
Query: 667 QASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPS---HVIEMSS 723
+ S+ M R ++ T+ + K+ ++ +S LPIA S H +
Sbjct: 1166 VSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHG 1225
Query: 724 SRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDE 783
S+ P A +P P++ V + G V AS + + D
Sbjct: 1226 PLSSSAPGASTQP--PPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDA 1283
Query: 784 DEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQ 843
DE+ + K +L+ +Q+AG K L Q PPPPA
Sbjct: 1284 DEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQ---PPPPPATL 1340
Query: 844 EEQALSPSPTNGNPLLPFPGAQVRQNV 870
+ P P P P P Q+ V
Sbjct: 1341 KVAEPPPRP----PPPPPPTGQMNGTV 1363
Score = 82.0 bits (201), Expect = 3e-15
Identities = 115/424 (27%), Positives = 152/424 (35%), Gaps = 77/424 (18%)
Query: 345 LPVQHPHHPSPP------QGMHMPPQ----LETPRMMMTPP----------PVTPQQPKN 384
LP Q P+ P QG+ +PP L TP ++ P PV QP
Sbjct: 566 LPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPA- 624
Query: 385 IHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLP 444
P V TP+ + L +Q P + PP+ TP P P S P ++
Sbjct: 625 ----PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT--TPQPSPGLASSPEKIV 678
Query: 445 LQDQWRAPPPP---QDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQ 501
L A P QD FL P+ S L P P ++++ P P Q
Sbjct: 679 LGQPPSATPTAILTQDSLQMFL-----PQERSQQPLSAEGPHLSVPASVIVSA--PPPAQ 731
Query: 502 SPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPF 561
P P T P G P P + P P P IP P
Sbjct: 732 DPAPAT---PVAKGAGLGPQAPDSQA------SPAPA--------------PQIPAAAP- 767
Query: 562 LPGPGQPFLPTHTQPNLQGPL--HPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQH 619
L GPG P+ Q PL P LP PH P +P +PP + Q +PP +PP
Sbjct: 768 LKGPGPSSSPSLPH---QAPLGDSPHLPSPH---PTRPPSRPPSRPQSVSRPPSEPPLHP 821
Query: 620 QPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQ 679
PPPQ PP P + L VPPP P P +PQ+ P
Sbjct: 822 CPPPQAPPTLPGIFV---IQNQLGVPPPASNPAPTAPGPPQ-PPLRPQSQPPEGPLPPAP 877
Query: 680 GLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVS 739
L ++TS V+ + AP S+ +L PS S + P+ + P +
Sbjct: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDF-QLQFPPSQGPHKSP---TPPPTLHLVPEPA 933
Query: 740 ASPP 743
A PP
Sbjct: 934 APPP 937
Score = 45.4 bits (106), Expect = 3e-04
Identities = 135/624 (21%), Positives = 193/624 (30%), Gaps = 116/624 (18%)
Query: 464 GVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFP 523
G+ P P+ + R+P P P P + + +P PF G QG+ P
Sbjct: 330 GLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPK-LYQLTPKPFAPAGATLTIQGEPGALP 388
Query: 524 RERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLH 583
+ QP P L F G A + P P P
Sbjct: 389 Q--------QPKAPQN-LTFMAAGKAGQNVVLSG----FPAPALQANVFKQPPATTTGAA 435
Query: 584 PPLPPPHQPQP-------QQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHH 636
PP PP +P Q P QH P Q P P Q P Q
Sbjct: 436 PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA--PAVQLPQQ-------- 485
Query: 637 HHHHHLSVPPPPLMPMSQPQFRPHVQ---TAQPQASSSRMQCPQRQG---LRHNT--TSQ 688
LS P + PH A P ++ + P G H+ ++
Sbjct: 486 -----LSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAH 540
Query: 689 NVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVA 748
+S P+Q QP L ++P++ + + S+ + A + + P AVA
Sbjct: 541 ILSAAPIQVGQPA------LFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVA 594
Query: 749 GSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQK 808
+ G V+PA+P A E A L ++ + +
Sbjct: 595 MLNTPDGL----VQPATPAAATGEAAPV---------------LTVQPAPQAPPAVSTPL 635
Query: 809 ELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQ 868
L QQ Q QQ AP P A QA +P P+ G P +
Sbjct: 636 PLGLQQP-------------QAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP 682
Query: 869 NVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLH 928
+ QD S+ P+ + P SA +G + + + P P
Sbjct: 683 PSATPTAILTQD-SLQMFLPQERSQQPLSA----EGPHLSVPASVIVSAPPPAQDPAPAT 737
Query: 929 KVL------PIKPADVEEPA-VPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHI 981
V P P PA PQ P A ++G PG + + + GD PH+
Sbjct: 738 PVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG------PGPSSSPSLPHQAPLGDSPHL 791
Query: 982 SSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPP---------------EVG-PQPARKVT 1025
S S P +P P PP ++G P PA
Sbjct: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
Query: 1026 LTRGGLQQPPHLPAGPHAHSPVPP 1049
T G QPP P P+PP
Sbjct: 852 PTAPGPPQPPLRPQSQPPEGPLPP 875
Score = 39.3 bits (90), Expect = 0.022
Identities = 69/258 (26%), Positives = 93/258 (36%), Gaps = 44/258 (17%)
Query: 607 PPHQPPHQPPPQH----QPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQP-QFRPHV 661
P HQPP PPP +PPP+ PP PP Q + H PPP P +P PH
Sbjct: 1329 PVHQPP--PPPATLKVAEPPPRPPPPPPPTGQMNGTVDH----PPPAAPERKPLGTAPH- 1381
Query: 662 QTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEM 721
CP R LR T +NV + P A R P+ P+ V E
Sbjct: 1382 -------------CP-RLPLR-KTYRENVGGPGAPEGTP-AGRARGGSPAPL-PAKVDEA 1424
Query: 722 SSS--RCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETE 779
+S R A ++ + PP A + G + + P + K E+
Sbjct: 1425 TSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSES----- 1479
Query: 780 FPDEDEETRLYRLKIEEQKRLREEILKQKE--LRRQQQAGARKKELLERLAQQQQQLYAP 837
PD D+ + + + L E + + L QQ G A A
Sbjct: 1480 -PDVDQAS--FSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTP--AS 1534
Query: 838 PPPAEQEEQALSPSPTNG 855
PPP + E A PS NG
Sbjct: 1535 PPPLHRPE-AYPPSSHNG 1551
Score = 34.7 bits (78), Expect = 0.55
Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 3/50 (6%)
Query: 581 PLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHP 630
P+H P PPP + +P +PPP PP PPP P + P
Sbjct: 1329 PVHQPPPPPATLKVAEPPPRPPP---PPPPTGQMNGTVDHPPPAAPERKP 1375
Score = 33.5 bits (75), Expect = 1.2
Identities = 50/232 (21%), Positives = 66/232 (28%), Gaps = 23/232 (9%)
Query: 413 AVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE-PRF 471
A+ P P PP P P PP + PPP + LG + PR
Sbjct: 1326 ALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRL 1385
Query: 472 PSHLFLEQRSPPPPPP---PPTLLNSSHPVPTQSPLPFTQPG-----PAFNQQGQQPVFP 523
P + P P P P P + + G A + Q +
Sbjct: 1386 PLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRML- 1444
Query: 524 RERPVRPALQPPGPVGILHFSQPGSATTR------PFIPPRQPFLPGPGQPFLPTHTQPN 577
+ P PA G + PG + P + P L H Q
Sbjct: 1445 KGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSA 1504
Query: 578 LQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQH 629
+ L+ P P P P H P PPP H+P P H
Sbjct: 1505 IDSILNLQQAPGRTPAPSYP-------HAASAGTPASPPPLHRPEAYPPSSH 1549
Score = 31.6 bits (70), Expect = 4.6
Identities = 18/49 (36%), Positives = 20/49 (40%), Gaps = 9/49 (18%)
Query: 304 HRPALLPTQPPVVPQAP---------PPPPPPPQQQPIRSLFQPQPLQP 343
H AL P P P A PPPPPPP Q ++ P P P
Sbjct: 1323 HNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP 1371
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 98.2 bits (243), Expect = 4e-20
Identities = 98/313 (31%), Positives = 112/313 (35%), Gaps = 88/313 (28%)
Query: 396 VTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPV------PNSFSQPPRLPLQDQW 449
V+P+ PL PVP P P P P PP+ P H PGP P +F+ P +P
Sbjct: 655 VSPIPKPL-PVPVPPIPVPAPITVP-PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFG 712
Query: 450 RAPPPPQDRDPFFLGVSGEPRF-PSHL---FLEQRSPPPPPPPPTLLNSSHPVPTQSPLP 505
PPP PF P F P HL FL PPPP PP + H P P
Sbjct: 713 PGVPPPPPPPPFL-----RPGFNPMHLPPGFLPP-GPPPPITPPVSIPPPHTPPISIPNL 766
Query: 506 FT------QPGPAFNQQGQQ--PVFPRERPVRPALQP----------PGPVGILHFSQPG 547
+ + G + G P P P P QP PGPV L G
Sbjct: 767 VSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTG 826
Query: 548 SATTRPFIPP--RQPFLPGPGQ---PFLPTHTQPNLQGPLHPP-------LPPPH----- 590
RP + P R P +P P P +P P PP +PPPH
Sbjct: 827 LLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGP 886
Query: 591 --------------------------------QPQPQQPQQQPPPQ--HQPPHQPPHQPP 616
Q PQQPQQQP PQ QP Q QPP
Sbjct: 887 FPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPP 946
Query: 617 PQHQPPP-QHPPQ 628
P QPPP Q PQ
Sbjct: 947 PSQQPPPTQQQPQ 959
Score = 57.0 bits (136), Expect = 1e-07
Identities = 71/280 (25%), Positives = 92/280 (32%), Gaps = 80/280 (28%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQP-LLPVQHPHHPSPPQGMHMP-- 362
P L P P PPPPPPPP +P F P L P LP P +PP + P
Sbjct: 702 PPLGIPPPGFGPGVPPPPPPPPFLRPG---FNPMHLPPGFLPPGPPPPITPPVSIPPPHT 758
Query: 363 PQLETPRMM--------------MTPPPVTPQQPKNIHINPHFK------------GTVV 396
P + P ++ M V P P N+ P + G V+
Sbjct: 759 PPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI 818
Query: 397 ------------TPVQVPLLPVPSQPRPAVGPQRFP------GPPEFPQHTPGPVPNSFS 438
P +PL P P P + QRFP PP P P P F+
Sbjct: 819 GLQAPSTGLLGARPGLIPLQRPPGMPPPHL--QRFPLMPPRPMPPHMMHRGPPPGPGGFA 876
Query: 439 QPPRLPLQDQWR-------------------APPPPQDRDPFFLGVSGEPRFPSHLFLEQ 479
PP ++ + P P+DRD G P+ P +Q
Sbjct: 877 MPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRD----GRQQPPQQP-----QQ 927
Query: 480 RSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQ 519
+ P P P P P+Q P P Q F +Q
Sbjct: 928 QPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQ 967
Score = 52.0 bits (123), Expect = 3e-06
Identities = 67/237 (28%), Positives = 82/237 (34%), Gaps = 62/237 (26%)
Query: 519 QPVFPRERPVRPALQPPGPVGILHFSQPGSATTRP-FIPPRQPFLPGPGQPFLPTHTQPN 577
+PV P +P+ P PP PV P T P +PP QP G P + P
Sbjct: 653 EPVSPIPKPL-PVPVPPIPV-------PAPITVPPPQVPPHQP-----GPPVVGALQPPA 699
Query: 578 LQGPLHPPLPPPHQPQPQQPQQQPP---PQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQ 634
PL P PP P P PP P P H PP PP PPP PP
Sbjct: 700 FTPPLGIP-PPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-GPPPPITPP------- 750
Query: 635 HHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRP 694
+S+PPP P+S P G R N S + K
Sbjct: 751 -------VSIPPPHTPPISIPNL--------------------VSGARGNAESGDSVKMY 783
Query: 695 MQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSR 751
+ P AP N LP P V + S T P++ PS + G+R
Sbjct: 784 GSAVPPAAPTN-----LPTPP--VTQPVS--LLGTQGVAPGPVIGLQAPSTGLLGAR 831
Score = 46.6 bits (109), Expect = 1e-04
Identities = 71/301 (23%), Positives = 100/301 (33%), Gaps = 53/301 (17%)
Query: 353 PSPPQGMHMPPQLETPRMMMTPPPVTPQQPKN---IHINPHFKGTVVTPVQVPLLPVPSQ 409
P P + PP TP + P PQ P + + F+ T +Q L
Sbjct: 156 PPPVKVSSEPPTQATPNSV----PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211
Query: 410 PRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQ------------- 456
P+P + P + P P + + PPP Q
Sbjct: 212 PKP-----QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFD 266
Query: 457 -DRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSP---LPFTQPGPA 512
D +P + S + + + PP P T+ ++ P P PF PG
Sbjct: 267 YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDG 326
Query: 513 FNQQGQQPVFPRERPVRPALQPPGPVGI----LHFSQPGSATTRPFIPPRQPFLPGPGQP 568
QQP + + + + P +GI +H P +PP PG
Sbjct: 327 M----QQPAYTQHQNMDQF--QPRMMGIQQDPMHHQVP--------LPPNGQM---PGFG 369
Query: 569 FLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQ 628
LPT P + P+ PP PP QP Q Q P Q PHQ Q QP Q +
Sbjct: 370 LLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQ---QEMEVEQPCIQEVKR 426
Query: 629 H 629
H
Sbjct: 427 H 427
Score = 45.1 bits (105), Expect = 4e-04
Identities = 87/352 (24%), Positives = 114/352 (32%), Gaps = 63/352 (17%)
Query: 420 PGPPEFPQHTPGP--VPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFL 477
P PP P PNS P+LP D + A F G+ L
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQ------LFQTTQGQQL---QQIL 205
Query: 478 EQRSPPPPPPPPTLLNSS----HPVPTQSPLPFTQPGP---AFNQQGQQPVFPRERPVRP 530
+ PP P P L N+ + Q TQP AF Q+ F ++ R
Sbjct: 206 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 265
Query: 531 ALQP-PGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPP 589
P V + TT P P PT T P P PPP
Sbjct: 266 DYDDEPEAVEESKKEDTTAVTTTA---------PAAAVPPAPTATVPAAAAPAAASPPPP 316
Query: 590 HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQ-----HHHHHHHLSV 644
Q P P Q P HQ Q QP Q P HQ + +
Sbjct: 317 -----QAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 371
Query: 645 PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704
P PP PM+QP P QP +S + Q ++ ++++P QQ
Sbjct: 372 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQ------------NEPLTQKPHQQEMEV--- 416
Query: 705 NSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGK 756
E P MS +R S + SA P R+ +GSRS + +
Sbjct: 417 -----EQPCIQEVKRHMSDNRKSRSRSASRSP-----KRRRSRSGSRSRRSR 458
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/45 (53%), Positives = 27/45 (60%), Gaps = 5/45 (11%)
Query: 308 LLPTQPPVVPQAPPP-PPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351
LLPT PP P A P PP PP QQP ++ FQ Q +PL Q PH
Sbjct: 370 LLPT-PPFPPMAQPVIPPTPPVQQPFQASFQAQN-EPL--TQKPH 410
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 98.2 bits (243), Expect = 4e-20
Identities = 183/776 (23%), Positives = 263/776 (33%), Gaps = 166/776 (21%)
Query: 290 DQRRESTERG---RMKDHRPAL-LPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLL 345
D R T++ R + +P+L P++PP+ P P PP QQP QP P +P
Sbjct: 277 DASRPQTKQADIVRGESVKPSLPSPSKPPI---QQPTPGKPPAQQPGHEKSQPGPAKP-- 331
Query: 346 PVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVP-LL 404
P+ P G+ P QQP GTV PVQ P
Sbjct: 332 -------PAQPSGLTKP---------------LAQQP----------GTVKPPVQPPGTT 359
Query: 405 PVPSQPR-PAVGPQRFPGPPEFPQHTPGPVPNSFSQPP---RLPLQDQWRAPPPPQDRDP 460
P+QP PA P + G + PGP + +QPP + P Q A PP Q
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGP--KALAQPPGVGKTPAQQPGPAKPPTQ---- 413
Query: 461 FFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQP 520
Q P P L S P + P QPGP G+ P
Sbjct: 414 ------------------QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP-----GKIP 450
Query: 521 VFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQG 580
+ P + + Q GP ++P S P PP Q PGP +P P G
Sbjct: 451 A-QQAGPGKTSAQQTGP------TKPPSQLPGPAKPPPQQ--PGPAKP------PPQQPG 495
Query: 581 PLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHH 640
PP P +P P QQP P P QP PP QP P P
Sbjct: 496 SAKPPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS-------- 545
Query: 641 HLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
P P +Q +P QT S +Q P T S + + P Q +
Sbjct: 546 -------PAKPSAQQSTKPVSQT----GSGKPLQPP--------TVSPSAKQPPSQGLPK 586
Query: 701 TAPRNSNLRELPIAPSHVIEMSS------------SRCSATPSAQVKPIVS----ASPPS 744
T N EL + HV E ++ S C P+ + +
Sbjct: 587 TICPLCNTTELLL---HVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
Query: 745 RAVAGSRS---SQGKTEVKVKPASPV-AQPKEEAKTETEFPDEDEETRLYRLKIEEQKRL 800
RA+ G + S + ++K P + A K + + P +D + K E K+
Sbjct: 644 RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK- 702
Query: 801 REEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLP 860
++KQ L A A++ + L++ P PP E PS + P+
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSK-------PAPPKEPS----VPSEQDKAPV-- 749
Query: 861 FPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVP 920
K +VK +S+ T +PSS +Q Q ++ K L+ P
Sbjct: 750 -----ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEE-KTTPPLKTDSAKP 802
Query: 921 QSQTQPL-HKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGP 979
P KV P + PA ++ S G ++K + +
Sbjct: 803 SQSFPPTGEKVSPFDSKAIPRPA--SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQT 860
Query: 980 HISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPP 1035
+S K + G G GQ PQ + +R+ +L G + P
Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Score = 74.3 bits (181), Expect = 6e-13
Identities = 181/896 (20%), Positives = 291/896 (32%), Gaps = 141/896 (15%)
Query: 281 GPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQP 340
G + + G + + + G K P +PP PQ P P PPPQ QP
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP--PQQPGPAKPPPQ--------QPGS 496
Query: 341 LQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQ 400
+P P Q P PP PQQP +P G+ P Q
Sbjct: 497 AKP--PSQQPGSTKPP----------------------PQQPGPAKPSPQQPGSTKPPSQ 532
Query: 401 VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDP 460
P PS +P+ P P Q T PV + S P P A PP
Sbjct: 533 QPGSAKPSAQQPS------PAKPSAQQSTK-PVSQTGSGKPLQPPTVSPSAKQPPS---- 581
Query: 461 FFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGP--------- 511
G P+ L P + T L P P
Sbjct: 582 -----QGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
Query: 512 AFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLP 571
N Q ++ + PV + QP + TT + P P
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPK--------LKTAPVTTTSAVSKSSP---------QP 679
Query: 572 THTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHP- 630
T P L +P+ P + P H P QPP PP+ P
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739
Query: 631 -PQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQN 689
P Q P ++ + T +P SS++Q + + +
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE--KTTPPLKT 797
Query: 690 VSKRPMQQMQPT----APRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSR 745
S +P Q PT +P +S P + S +I + QV P+ P +
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 746 A-VAGSRSSQGKTEVKVKPASPVAQPK--EEAKTETEFPDEDEETRLYRLKI-------E 795
A S K K P P +P + T + P E++R + L + +
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917
Query: 796 EQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNG 855
Q +E + K ++ L+ Q + P ++ A S PT+
Sbjct: 918 SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ 977
Query: 856 NPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQ 915
P P Q + VK + + P++ ++ + +Q +K
Sbjct: 978 GP--PKSTGQAPPAPAKSIPVKKETKA------------PAAEKLEPKAEQAPTVK---- 1019
Query: 916 TRTVPQSQTQPLHKVLPIKPAD--VEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNS 973
+T+ K PIK + EP P +P+ T P K + N
Sbjct: 1020 -------RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL----NI 1068
Query: 974 GGGDGPHISS----KVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRG 1029
G D P+ ++ K +V L G F+P + + + Q R ++ G
Sbjct: 1069 GSKDPPNFNTCTECKNQVCNLCG--------FNPTPHLTEIQEWLCLNCQTQRAISGQLG 1120
Query: 1030 GLQQPPHLPAGPHAH-SPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNL 1088
+++ P P+GP A PVP S + P + ++ + + V + L K+ L
Sbjct: 1121 DIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETL 1180
Query: 1089 RVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPI-QSLQMLPQQRKAIAKFKEP 1143
+ K P V + + S + S L P+ + +++P++ K ++ K+P
Sbjct: 1181 SME--KIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234
Score = 48.1 bits (113), Expect = 5e-05
Identities = 61/241 (25%), Positives = 82/241 (34%), Gaps = 41/241 (17%)
Query: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPL---QPLLPVQHPHHPSPP---------- 356
P PP P PPPPPPPP P+ P+P + L V P + P
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 357 QGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGP 416
+ L R+ T PP P +P +I G V T P P P P+P +
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIP-----SGLVFTHRPEPSKP-PIAPKPVI-- 2516
Query: 417 QRFPGPPEFPQHTPGPV-----PNSFSQPPRLPL----QDQWRAPPPPQDRDPFFLGVSG 467
P+ P T P P S + L ++ P P P
Sbjct: 2517 ------PQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPH--SNKS 2568
Query: 468 EPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERP 527
PRF L P P T +SS +Q+ + P+ + +PVF P
Sbjct: 2569 SPRFSKSLTETYVVITLPSEPGTPTDSS---ASQAITSWPLGSPSKDLVSVEPVFSVVPP 2625
Query: 528 V 528
V
Sbjct: 2626 V 2626
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 10/78 (12%)
Query: 589 PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPP 648
P +P+P QPP PP PPP PPP PP PP + P P
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP----------TSPKPT 2436
Query: 649 LMPMSQPQFRPHVQTAQP 666
++P + V TA P
Sbjct: 2437 ILPKKKLTVASPVTTATP 2454
Score = 42.0 bits (97), Expect = 0.003
Identities = 95/415 (22%), Positives = 139/415 (33%), Gaps = 67/415 (16%)
Query: 579 QGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHH 638
QG + PP Q QP +P P+ Q P + P Q Q P Q P + +
Sbjct: 200 QGKPEGIIKPPLQQQP----PKPIPKQQGPGRDPLQ---QDGTPKSISSQQPEKIK---- 248
Query: 639 HHHLSVPPPPLMPMSQPQFRPHVQTAQ--PQASSSRMQCPQRQGLRHNTTSQNV---SKR 693
S PP P+ P P A+ Q +SR Q Q +R + ++ SK
Sbjct: 249 ----SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304
Query: 694 PMQQMQPTAPRNSNLRELPIAPSH-VIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRS 752
P+QQ P P P H + ++ A PS KP+ A P V
Sbjct: 305 PIQQPTPGKPPAQQ-------PGHEKSQPGPAKPPAQPSGLTKPL--AQQPG-TVKPPVQ 354
Query: 753 SQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRR 812
G T+ +P P P ++ T +E P ++ K L +
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQ--TGSEKPSSEQP-------------------GPKALAQ 393
Query: 813 QQQAGARKKELLERLAQQQQQLYAPPPPAEQ---EEQALSPSPTNGNPLLPFPGAQVRQN 869
G + QQ+ P P A+Q + A +P PT P PG Q
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 870 VKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQG------QQMKALKHLRQT--RTVPQ 921
K +P + P+ Q G QQ + K Q T P
Sbjct: 454 AGPG---KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 922 SQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGG 976
Q K P +P + P+ S Q +P KP +++ + +G G
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ-QPSPAKPSAQQSTKPVSQTGSG 564
Score = 40.8 bits (94), Expect = 0.008
Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 6/79 (7%)
Query: 543 FSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPP 602
F Q A+ P P LP +PF + + L PP PPP P P PP
Sbjct: 2367 FGQEKPASQLPSGSPSVSSLPAKPRPFFRSSS---LDISAQPPPPPP---PPPPPPPPPP 2420
Query: 603 PQHQPPHQPPHQPPPQHQP 621
P PP PP P P P
Sbjct: 2421 PPPPPPLPPPTSPKPTILP 2439
Score = 37.7 bits (86), Expect = 0.065
Identities = 45/151 (29%), Positives = 56/151 (37%), Gaps = 20/151 (13%)
Query: 469 PRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPL-PFTQPGPAFNQQGQQPV---FPR 524
P F S PPPPPPPP P P PL P T P P + + V
Sbjct: 2392 PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTT 2451
Query: 525 ERPVRPALQPPGPVGILHFSQPGSATTR------PFIPPRQPFLPGPGQPFLPTHTQPNL 578
P+ A+ +L + G TR P +PP+ +P G F TH
Sbjct: 2452 ATPLFDAVTTLETTAVLRSN--GLPVTRICTTAPPPVPPKPSSIPS-GLVF--THRPE-- 2504
Query: 579 QGPLHPPL-PPPHQPQPQQPQQQPPPQHQPP 608
P PP+ P P PQ Q+P H P
Sbjct: 2505 --PSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Score = 35.8 bits (81), Expect = 0.25
Identities = 78/427 (18%), Positives = 138/427 (32%), Gaps = 87/427 (20%)
Query: 690 VSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSR-----CSATPSAQVKPIVSASPPS 744
+S+ +Q+ R L + + P+ S R S P +P P
Sbjct: 48 LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107
Query: 745 RAVAGSRSSQG-KTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRL----------- 792
++ SR++ ++E K+ SP +E+K+ T+ +E + + +
Sbjct: 108 PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS 167
Query: 793 ----KIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQAL 848
K + + Q+E ++Q+ +++ E + + Q P P +Q+
Sbjct: 168 SVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR 227
Query: 849 SPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMK 908
P +G P SIS+ QP+ P QG
Sbjct: 228 DPLQQDGTPK-----------------------SISSQQPEKIKSQPPGTGKPIQG---- 260
Query: 909 ALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGR------PQDTKPG 962
P Q H LP++ + + PQT + ++G P +KP
Sbjct: 261 -----------PTQTPQTDHAKLPLQ----RDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 963 VKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPAR 1022
+++ + + + G G P QP L +P + QP
Sbjct: 306 IQQPTPGKPPA---------------QQPGHEKSQPGPAKPPAQPSGLTKP--LAQQPGT 348
Query: 1023 -KVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRL 1081
K + G +PP P GP G + P KA+ G G G
Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 1082 MPNKQNL 1088
P Q +
Sbjct: 409 KPPTQQV 415
Score = 34.7 bits (78), Expect = 0.55
Identities = 56/319 (17%), Positives = 117/319 (36%), Gaps = 54/319 (16%)
Query: 727 SATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVK--PASPVAQPKEEAKTETEFPDED 784
S TP + S S + + + K + K + P P+ E++ E E +E+
Sbjct: 1724 SFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEE 1783
Query: 785 EETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLER---LAQQQQQLYAPPP-- 839
E L +E KQ+E+ +QQ+ + KK ++ AQ++++ PP
Sbjct: 1784 E--------------LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSN 1829
Query: 840 --------PAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNV---QP 888
P E+ QA + + + + + + + + + + V
Sbjct: 1830 LSPIEDASPTEELRQAAEMEELHRSSCSEY-SPSIESDPEGFEISPEKIIEVQKVYKLPT 1888
Query: 889 KTSNFVPSSAN--MQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQT 946
S + P+ MQ +G Q K L+ + + HK A+ + +
Sbjct: 1889 AVSLYSPTDEQSIMQKEGSQ----KALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKE 1944
Query: 947 PRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQ 1006
P + + + ++ T +G DG ++ + E +GF +G+
Sbjct: 1945 PLYGGML-----IEDYIYESLVEDTYNGSVDGSLLTRQ----------EEENGFMQQKGR 1989
Query: 1007 PQRLPQPPEVGPQPARKVT 1025
Q++ ++ P +K+T
Sbjct: 1990 EQKIRLSEQIYEDPMQKIT 2008
Score = 34.7 bits (78), Expect = 0.55
Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 17/99 (17%)
Query: 543 FSQPGSATTRPFIPPRQPFLPGP-GQPFLPTHTQPNL-------QGPLHPPLPPPHQPQP 594
F P + T +PP P+ P LPT + Q L+ P+Q QP
Sbjct: 3867 FIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQP 3926
Query: 595 Q---------QPQQQPPPQHQPPHQPPHQPPPQHQPPPQ 624
PQ QP P QP +Q P Q Q P Q
Sbjct: 3927 TFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQ 3965
Score = 33.9 bits (76), Expect = 0.93
Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 22/76 (28%)
Query: 591 QPQPQQPQQQPPPQHQPPHQPPH----------QPPPQHQPPPQHPPQHPPQHQHHHHHH 640
+P Q P P P P QPPP PPP PP PP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPP-PPPPPP--------- 2420
Query: 641 HLSVPPPPLMPMSQPQ 656
PPPPL P + P+
Sbjct: 2421 --PPPPPPLPPPTSPK 2434
Score = 32.7 bits (73), Expect = 2.1
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 6/58 (10%)
Query: 784 DEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKEL------LERLAQQQQQLY 835
++E + + K+EE + +++ +L Q+E RQ Q R++ L LE++ Q QQQL+
Sbjct: 3247 EQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLH 3304
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 98.2 bits (243), Expect = 4e-20
Identities = 183/776 (23%), Positives = 263/776 (33%), Gaps = 166/776 (21%)
Query: 290 DQRRESTERG---RMKDHRPAL-LPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLL 345
D R T++ R + +P+L P++PP+ P P PP QQP QP P +P
Sbjct: 277 DASRPQTKQADIVRGESVKPSLPSPSKPPI---QQPTPGKPPAQQPGHEKSQPGPAKP-- 331
Query: 346 PVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVP-LL 404
P+ P G+ P QQP GTV PVQ P
Sbjct: 332 -------PAQPSGLTKP---------------LAQQP----------GTVKPPVQPPGTT 359
Query: 405 PVPSQPR-PAVGPQRFPGPPEFPQHTPGPVPNSFSQPP---RLPLQDQWRAPPPPQDRDP 460
P+QP PA P + G + PGP + +QPP + P Q A PP Q
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGP--KALAQPPGVGKTPAQQPGPAKPPTQ---- 413
Query: 461 FFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQP 520
Q P P L S P + P QPGP G+ P
Sbjct: 414 ------------------QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP-----GKIP 450
Query: 521 VFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQG 580
+ P + + Q GP ++P S P PP Q PGP +P P G
Sbjct: 451 A-QQAGPGKTSAQQTGP------TKPPSQLPGPAKPPPQQ--PGPAKP------PPQQPG 495
Query: 581 PLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHH 640
PP P +P P QQP P P QP PP QP P P
Sbjct: 496 SAKPPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS-------- 545
Query: 641 HLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
P P +Q +P QT S +Q P T S + + P Q +
Sbjct: 546 -------PAKPSAQQSTKPVSQT----GSGKPLQPP--------TVSPSAKQPPSQGLPK 586
Query: 701 TAPRNSNLRELPIAPSHVIEMSS------------SRCSATPSAQVKPIVS----ASPPS 744
T N EL + HV E ++ S C P+ + +
Sbjct: 587 TICPLCNTTELLL---HVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
Query: 745 RAVAGSRS---SQGKTEVKVKPASPV-AQPKEEAKTETEFPDEDEETRLYRLKIEEQKRL 800
RA+ G + S + ++K P + A K + + P +D + K E K+
Sbjct: 644 RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK- 702
Query: 801 REEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLP 860
++KQ L A A++ + L++ P PP E PS + P+
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSK-------PAPPKEPS----VPSEQDKAPV-- 749
Query: 861 FPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVP 920
K +VK +S+ T +PSS +Q Q ++ K L+ P
Sbjct: 750 -----ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQSQAEE-KTTPPLKTDSAKP 802
Query: 921 QSQTQPL-HKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGP 979
P KV P + PA ++ S G ++K + +
Sbjct: 803 SQSFPPTGEKVSPFDSKAIPRPA--SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQT 860
Query: 980 HISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPP 1035
+S K + G G GQ PQ + +R+ +L G + P
Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Score = 74.3 bits (181), Expect = 6e-13
Identities = 181/896 (20%), Positives = 291/896 (32%), Gaps = 141/896 (15%)
Query: 281 GPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQP 340
G + + G + + + G K P +PP PQ P P PPPQ QP
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP--PQQPGPAKPPPQ--------QPGS 496
Query: 341 LQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQ 400
+P P Q P PP PQQP +P G+ P Q
Sbjct: 497 AKP--PSQQPGSTKPP----------------------PQQPGPAKPSPQQPGSTKPPSQ 532
Query: 401 VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDP 460
P PS +P+ P P Q T PV + S P P A PP
Sbjct: 533 QPGSAKPSAQQPS------PAKPSAQQSTK-PVSQTGSGKPLQPPTVSPSAKQPPS---- 581
Query: 461 FFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGP--------- 511
G P+ L P + T L P P
Sbjct: 582 -----QGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
Query: 512 AFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLP 571
N Q ++ + PV + QP + TT + P P
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPK--------LKTAPVTTTSAVSKSSP---------QP 679
Query: 572 THTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHP- 630
T P L +P+ P + P H P QPP PP+ P
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739
Query: 631 -PQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQN 689
P Q P ++ + T +P SS++Q + + +
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE--KTTPPLKT 797
Query: 690 VSKRPMQQMQPT----APRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSR 745
S +P Q PT +P +S P + S +I + QV P+ P +
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 746 A-VAGSRSSQGKTEVKVKPASPVAQPK--EEAKTETEFPDEDEETRLYRLKI-------E 795
A S K K P P +P + T + P E++R + L + +
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917
Query: 796 EQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNG 855
Q +E + K ++ L+ Q + P ++ A S PT+
Sbjct: 918 SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ 977
Query: 856 NPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQ 915
P P Q + VK + + P++ ++ + +Q +K
Sbjct: 978 GP--PKSTGQAPPAPAKSIPVKKETKA------------PAAEKLEPKAEQAPTVK---- 1019
Query: 916 TRTVPQSQTQPLHKVLPIKPAD--VEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNS 973
+T+ K PIK + EP P +P+ T P K + N
Sbjct: 1020 -------RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL----NI 1068
Query: 974 GGGDGPHISS----KVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRG 1029
G D P+ ++ K +V L G F+P + + + Q R ++ G
Sbjct: 1069 GSKDPPNFNTCTECKNQVCNLCG--------FNPTPHLTEIQEWLCLNCQTQRAISGQLG 1120
Query: 1030 GLQQPPHLPAGPHAH-SPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNL 1088
+++ P P+GP A PVP S + P + ++ + + V + L K+ L
Sbjct: 1121 DIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETL 1180
Query: 1089 RVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPI-QSLQMLPQQRKAIAKFKEP 1143
+ K P V + + S + S L P+ + +++P++ K ++ K+P
Sbjct: 1181 SME--KIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234
Score = 48.1 bits (113), Expect = 5e-05
Identities = 61/241 (25%), Positives = 82/241 (34%), Gaps = 41/241 (17%)
Query: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPL---QPLLPVQHPHHPSPP---------- 356
P PP P PPPPPPPP P+ P+P + L V P + P
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 357 QGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGP 416
+ L R+ T PP P +P +I G V T P P P P+P +
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIP-----SGLVFTHRPEPSKP-PIAPKPVI-- 2516
Query: 417 QRFPGPPEFPQHTPGPV-----PNSFSQPPRLPL----QDQWRAPPPPQDRDPFFLGVSG 467
P+ P T P P S + L ++ P P P
Sbjct: 2517 ------PQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPH--SNKS 2568
Query: 468 EPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERP 527
PRF L P P T +SS +Q+ + P+ + +PVF P
Sbjct: 2569 SPRFSKSLTETYVVITLPSEPGTPTDSS---ASQAITSWPLGSPSKDLVSVEPVFSVVPP 2625
Query: 528 V 528
V
Sbjct: 2626 V 2626
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 10/78 (12%)
Query: 589 PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPP 648
P +P+P QPP PP PPP PPP PP PP + P P
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP----------TSPKPT 2436
Query: 649 LMPMSQPQFRPHVQTAQP 666
++P + V TA P
Sbjct: 2437 ILPKKKLTVASPVTTATP 2454
Score = 42.0 bits (97), Expect = 0.003
Identities = 95/415 (22%), Positives = 139/415 (33%), Gaps = 67/415 (16%)
Query: 579 QGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHH 638
QG + PP Q QP +P P+ Q P + P Q Q P Q P + +
Sbjct: 200 QGKPEGIIKPPLQQQP----PKPIPKQQGPGRDPLQ---QDGTPKSISSQQPEKIK---- 248
Query: 639 HHHLSVPPPPLMPMSQPQFRPHVQTAQ--PQASSSRMQCPQRQGLRHNTTSQNV---SKR 693
S PP P+ P P A+ Q +SR Q Q +R + ++ SK
Sbjct: 249 ----SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304
Query: 694 PMQQMQPTAPRNSNLRELPIAPSH-VIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRS 752
P+QQ P P P H + ++ A PS KP+ A P V
Sbjct: 305 PIQQPTPGKPPAQQ-------PGHEKSQPGPAKPPAQPSGLTKPL--AQQPG-TVKPPVQ 354
Query: 753 SQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRR 812
G T+ +P P P ++ T +E P ++ K L +
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQ--TGSEKPSSEQP-------------------GPKALAQ 393
Query: 813 QQQAGARKKELLERLAQQQQQLYAPPPPAEQ---EEQALSPSPTNGNPLLPFPGAQVRQN 869
G + QQ+ P P A+Q + A +P PT P PG Q
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 870 VKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQG------QQMKALKHLRQT--RTVPQ 921
K +P + P+ Q G QQ + K Q T P
Sbjct: 454 AGPG---KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 922 SQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGG 976
Q K P +P + P+ S Q +P KP +++ + +G G
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ-QPSPAKPSAQQSTKPVSQTGSG 564
Score = 40.8 bits (94), Expect = 0.008
Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 6/79 (7%)
Query: 543 FSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPP 602
F Q A+ P P LP +PF + + L PP PPP P P PP
Sbjct: 2367 FGQEKPASQLPSGSPSVSSLPAKPRPFFRSSS---LDISAQPPPPPP---PPPPPPPPPP 2420
Query: 603 PQHQPPHQPPHQPPPQHQP 621
P PP PP P P P
Sbjct: 2421 PPPPPPLPPPTSPKPTILP 2439
Score = 37.7 bits (86), Expect = 0.065
Identities = 45/151 (29%), Positives = 56/151 (37%), Gaps = 20/151 (13%)
Query: 469 PRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPL-PFTQPGPAFNQQGQQPV---FPR 524
P F S PPPPPPPP P P PL P T P P + + V
Sbjct: 2392 PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTT 2451
Query: 525 ERPVRPALQPPGPVGILHFSQPGSATTR------PFIPPRQPFLPGPGQPFLPTHTQPNL 578
P+ A+ +L + G TR P +PP+ +P G F TH
Sbjct: 2452 ATPLFDAVTTLETTAVLRSN--GLPVTRICTTAPPPVPPKPSSIPS-GLVF--THRPE-- 2504
Query: 579 QGPLHPPL-PPPHQPQPQQPQQQPPPQHQPP 608
P PP+ P P PQ Q+P H P
Sbjct: 2505 --PSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Score = 35.8 bits (81), Expect = 0.25
Identities = 78/427 (18%), Positives = 138/427 (32%), Gaps = 87/427 (20%)
Query: 690 VSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSR-----CSATPSAQVKPIVSASPPS 744
+S+ +Q+ R L + + P+ S R S P +P P
Sbjct: 48 LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107
Query: 745 RAVAGSRSSQG-KTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRL----------- 792
++ SR++ ++E K+ SP +E+K+ T+ +E + + +
Sbjct: 108 PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS 167
Query: 793 ----KIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQAL 848
K + + Q+E ++Q+ +++ E + + Q P P +Q+
Sbjct: 168 SVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR 227
Query: 849 SPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMK 908
P +G P SIS+ QP+ P QG
Sbjct: 228 DPLQQDGTPK-----------------------SISSQQPEKIKSQPPGTGKPIQG---- 260
Query: 909 ALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGR------PQDTKPG 962
P Q H LP++ + + PQT + ++G P +KP
Sbjct: 261 -----------PTQTPQTDHAKLPLQ----RDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 963 VKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPAR 1022
+++ + + + G G P QP L +P + QP
Sbjct: 306 IQQPTPGKPPA---------------QQPGHEKSQPGPAKPPAQPSGLTKP--LAQQPGT 348
Query: 1023 -KVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRL 1081
K + G +PP P GP G + P KA+ G G G
Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 1082 MPNKQNL 1088
P Q +
Sbjct: 409 KPPTQQV 415
Score = 34.7 bits (78), Expect = 0.55
Identities = 56/319 (17%), Positives = 117/319 (36%), Gaps = 54/319 (16%)
Query: 727 SATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVK--PASPVAQPKEEAKTETEFPDED 784
S TP + S S + + + K + K + P P+ E++ E E +E+
Sbjct: 1724 SFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEE 1783
Query: 785 EETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLER---LAQQQQQLYAPPP-- 839
E L +E KQ+E+ +QQ+ + KK ++ AQ++++ PP
Sbjct: 1784 E--------------LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSN 1829
Query: 840 --------PAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNV---QP 888
P E+ QA + + + + + + + + + + V
Sbjct: 1830 LSPIEDASPTEELRQAAEMEELHRSSCSEY-SPSIESDPEGFEISPEKIIEVQKVYKLPT 1888
Query: 889 KTSNFVPSSAN--MQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQT 946
S + P+ MQ +G Q K L+ + + HK A+ + +
Sbjct: 1889 AVSLYSPTDEQSIMQKEGSQ----KALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKE 1944
Query: 947 PRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQ 1006
P + + + ++ T +G DG ++ + E +GF +G+
Sbjct: 1945 PLYGGML-----IEDYIYESLVEDTYNGSVDGSLLTRQ----------EEENGFMQQKGR 1989
Query: 1007 PQRLPQPPEVGPQPARKVT 1025
Q++ ++ P +K+T
Sbjct: 1990 EQKIRLSEQIYEDPMQKIT 2008
Score = 34.7 bits (78), Expect = 0.55
Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 17/99 (17%)
Query: 543 FSQPGSATTRPFIPPRQPFLPGP-GQPFLPTHTQPNL-------QGPLHPPLPPPHQPQP 594
F P + T +PP P+ P LPT + Q L+ P+Q QP
Sbjct: 3867 FIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQP 3926
Query: 595 Q---------QPQQQPPPQHQPPHQPPHQPPPQHQPPPQ 624
PQ QP P QP +Q P Q Q P Q
Sbjct: 3927 TFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQ 3965
Score = 33.9 bits (76), Expect = 0.93
Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 22/76 (28%)
Query: 591 QPQPQQPQQQPPPQHQPPHQPPH----------QPPPQHQPPPQHPPQHPPQHQHHHHHH 640
+P Q P P P P QPPP PPP PP PP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPP-PPPPPP--------- 2420
Query: 641 HLSVPPPPLMPMSQPQ 656
PPPPL P + P+
Sbjct: 2421 --PPPPPPLPPPTSPK 2434
Score = 32.7 bits (73), Expect = 2.1
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 6/58 (10%)
Query: 784 DEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKEL------LERLAQQQQQLY 835
++E + + K+EE + +++ +L Q+E RQ Q R++ L LE++ Q QQQL+
Sbjct: 3247 EQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLH 3304
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 96.3 bits (238), Expect = 2e-19
Identities = 138/503 (27%), Positives = 185/503 (36%), Gaps = 76/503 (15%)
Query: 232 LSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQ 291
LSD+ ++ + +TL S EA +E+ ++ ++GR + L+ R
Sbjct: 644 LSDLDQKWNSTLQTLVASYEA------YEDLMKKSQEGRDFYADLESKVAALLERTQSTC 697
Query: 292 RRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQ-QPIRSLFQPQPLQPLLP--VQ 348
+ R ++ D L +PP P AP P P ++ + + + P+ L+ L P V
Sbjct: 698 QAREAARQQLLDRE---LKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVA 754
Query: 349 HPHHPSPPQG----MHMPPQL------ETPRMMMTP-PPVTPQQPKNIHINPHFKGTVVT 397
P P G +H PP P + P PP T P + I P G
Sbjct: 755 GPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQL-IQPRAPG---- 809
Query: 398 PVQVPLLPVPS-QPRPAVGPQRFPGPPEFPQHTPGPVPNSF-SQPPRLPLQDQWRAPPPP 455
P +P+ P P+ P PA P+ P PQH G V + + P P+ APPP
Sbjct: 810 PHAMPVAPGPALYPAPAYTPELGLVPRSSPQH--GVVSSPYVGVGPAPPVAGLPSAPPPQ 867
Query: 456 QDRDPFFLGV--------SGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFT 507
+ V S + PSH + +P P PPPP PVP PLP
Sbjct: 868 FSGPELAMAVRPATTTVDSIQAPIPSHT-APRPNPTPAPPPPCF-----PVPPPQPLPTP 921
Query: 508 QPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQ 567
PA +QP+ P + P G P P Q F P P Q
Sbjct: 922 YTYPA---GAKQPI-----PAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQ 973
Query: 568 PFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQ-----QQPPPQHQPPHQPPHQPP-PQHQP 621
LP P+L P P L PP P P PQ Q PPP H + P Q P P H
Sbjct: 974 QPLPLQ-HPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSG 1032
Query: 622 PPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGL 681
P PPQ H PPL P RP PQA+ ++ P G
Sbjct: 1033 ALPFPSPGPPQPPH-----------PPLAYGPAPSTRP----MGPQAAPLTIRGPSSAGQ 1077
Query: 682 RHNTTSQNVSKRPMQQMQPTAPR 704
+ S P P PR
Sbjct: 1078 STPSPHLVPSPAPSPGPGPVPPR 1100
Score = 84.3 bits (207), Expect = 6e-16
Identities = 97/339 (28%), Positives = 120/339 (35%), Gaps = 60/339 (17%)
Query: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQP---LLPVQHPHH-----------PSP 355
PTQ + P+AP P P P +L+ P L+P P H P+P
Sbjct: 799 PTQL-IQPRAPGPHAMPVAPGP--ALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAP 855
Query: 356 PQG---MHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRP 412
P PPQ P + M P T T V +Q P +PS P
Sbjct: 856 PVAGLPSAPPPQFSGPELAMAVRPAT---------------TTVDSIQAP---IPSHTAP 897
Query: 413 AVGPQRFPGPPEFPQHTPGPVPNSFSQPPR----LPLQDQWRAPPPPQDRDPFFLGVSGE 468
P P PP FP P P+P ++ P +P Q + + P P +G +
Sbjct: 898 RPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPR-IGPQPQ 956
Query: 469 PRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSP--LPFTQPGPAFNQQGQ--QPVFPR 524
P H Q P PP P L H P Q+P LP P P Q G QP P
Sbjct: 957 PHPQPHP--SQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPL 1014
Query: 525 ERPVRPA-LQPPGPV--GILHFSQPGSATTRPFIPPRQPFLPGPG---QPFLPTHTQPNL 578
+ P Q P P G L F PG P PP P GP +P P +
Sbjct: 1015 HTQLYPGPAQDPLPAHSGALPFPSPG-----PPQPPHPPLAYGPAPSTRPMGPQAAPLTI 1069
Query: 579 QGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPP 617
+GP P P P P PP P +PPP
Sbjct: 1070 RGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPP 1108
Score = 69.3 bits (168), Expect = 2e-11
Identities = 67/216 (31%), Positives = 87/216 (40%), Gaps = 35/216 (16%)
Query: 317 PQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPP 376
P+ P P P PQ P ++ F PQP Q LP+QHPH P +PPQ +P P
Sbjct: 949 PRIGPQPQPHPQPHPSQA-FGPQPPQQPLPLQHPHLFPPQAPGLLPPQ--------SPYP 999
Query: 377 VTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQ-PRPAVG---PQRFPGPPEFPQHTP-- 430
PQ P G P+ L P P+Q P PA P PGPP+ P H P
Sbjct: 1000 YAPQ--------PGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQ-PPHPPLA 1050
Query: 431 -GPVPNSFSQPPR-LPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPP-- 486
GP P++ P+ PL + + P + P + PP PP
Sbjct: 1051 YGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPV------PPRPPAA 1104
Query: 487 -PPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPV 521
PPP L + S P +Q G + G QP+
Sbjct: 1105 EPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPL 1140
Score = 58.5 bits (140), Expect = 4e-08
Identities = 86/316 (27%), Positives = 113/316 (35%), Gaps = 55/316 (17%)
Query: 432 PVPNSFSQPPRLPLQDQWRAPP---PPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPP 488
P P + P LP +++ A PP++ + PR P FL +P PP
Sbjct: 716 PPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPD-TFLGSATPLHFPPS 774
Query: 489 PTLLNSSHPVP--TQSPLP-FTQPGPAFNQQGQQPVFPRERPVRP--ALQPPGP----VG 539
P +S+ P P PLP T GP Q + P P PV P AL P +G
Sbjct: 775 P-FPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPG-PHAMPVAPGPALYPAPAYTPELG 832
Query: 540 ILHFSQPG-SATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGP---------------LH 583
++ S P + P++ P P LP+ P GP +
Sbjct: 833 LVPRSSPQHGVVSSPYVGVG----PAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQ 888
Query: 584 PPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLS 643
P+P P+P P PPP P PPPQ P P P Q HH
Sbjct: 889 APIPSHTAPRPN-PTPAPPPPCFPV------PPPQPLPTPYTYPAGAKQPIPAQHHFSSG 941
Query: 644 V----PPPPLMPMSQPQFRPHVQTA---QPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696
+ P P + P QP +PH A QP +Q P H Q P Q
Sbjct: 942 IPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHP------HLFPPQAPGLLPPQ 995
Query: 697 QMQPTAPRNSNLRELP 712
P AP+ L + P
Sbjct: 996 SPYPYAPQPGVLGQPP 1011
Score = 39.3 bits (90), Expect = 0.022
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 6/58 (10%)
Query: 577 NLQGPLHPP-LPPPHQPQPQQ-PQQQPPPQHQPPHQPPHQPPPQHQPP-PQHPPQHPP 631
+L GP PP LPP P+ P PPP P P P P+ +PP P+ P PP
Sbjct: 1519 SLPGPAEPPGLPPASLPESTPIPSSSPPPLSSP---LPEAPQPKEEPPVPEAPSSGPP 1573
Score = 37.7 bits (86), Expect = 0.065
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 20/135 (14%)
Query: 479 QRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPV-RPALQPPGP 537
QR PPP P +S + ++ LP Q G P+ + + + +++PPG
Sbjct: 1458 QRHGVPPPCKPL---ASASISQKNHLP--QDSQDLVLGGDVPISSIQATIAKLSIRPPGG 1512
Query: 538 VGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQP 597
+ S PG A PP P P +P+ + P L PL P+ QP
Sbjct: 1513 LESPVASLPGPAE-----PPGLPPASLPESTPIPSSSPPPLSSPL---------PEAPQP 1558
Query: 598 QQQPPPQHQPPHQPP 612
+++PP P PP
Sbjct: 1559 KEEPPVPEAPSSGPP 1573
Score = 31.2 bits (69), Expect = 6.0
Identities = 14/35 (40%), Positives = 18/35 (51%)
Query: 913 LRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTP 947
L ++ +P S PL LP P EEP VP+ P
Sbjct: 1534 LPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAP 1568
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 96.3 bits (238), Expect = 2e-19
Identities = 103/326 (31%), Positives = 119/326 (36%), Gaps = 60/326 (18%)
Query: 305 RPALLPTQPPVVPQAPPPPP----PPPQQQPIRSLFQPQPLQPLLPV----QHPHHPSPP 356
+P P Q PQ PPPP PPPQ RS P P +P P P P PP
Sbjct: 56 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPPPQGGNQPQGPPPP 114
Query: 357 QGMHM-PPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVG 415
G PP R PPP PQ P P +P P P P+
Sbjct: 115 PGKPQGPPPQGGNRPQGPPPPGKPQGP------PPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
Query: 416 PQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHL 475
PQ P PP PQ GP P +P P + + PPP D+ G+P+ P
Sbjct: 169 PQGPPPPPGKPQ---GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ 225
Query: 476 FLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPP 535
Q PPPPP Q P P Q G +P P P +P
Sbjct: 226 GGNQPQGPPPPPGKP----------QGPPP---------QGGNKPQGPP-----PPGKPQ 261
Query: 536 GPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQ 595
GP +Q GS + PP +P GP P N QGP PPP PQ
Sbjct: 262 GPP-----AQGGSKSQSARSPPGKP--QGP-----PQQEGNNPQGP-----PPPAGGNPQ 304
Query: 596 QPQQQPPPQHQPPHQPPHQPPPQHQP 621
QPQ P Q Q P +PP P P
Sbjct: 305 QPQAPPAGQPQGPPRPPQGGRPSRPP 330
Score = 95.1 bits (235), Expect = 3e-19
Identities = 105/344 (30%), Positives = 124/344 (36%), Gaps = 87/344 (25%)
Query: 317 PQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPP 376
PQ PPPPP PQ P + +PQ P P PQG PPQ + R +PP
Sbjct: 47 PQGPPPPPGKPQGPPPQGGNKPQGPPP---------PGKPQGP--PPQGDKSRSPRSPPG 95
Query: 377 VTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNS 436
PQ P P+ PQ P PP PQ GP P
Sbjct: 96 -KPQGPP--------------------------PQGGNQPQGPPPPPGKPQ---GPPPQG 125
Query: 437 FSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSH 496
++P P + + PPP D+ G+P+ P Q PPPPP
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG----KPQG 181
Query: 497 PVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVR-PALQPPGPVGILHFSQPGSATTRPFI 555
P P P P P QG P + R + P +P GP P +P
Sbjct: 182 PPPQGGKKPQGPPPPG-KPQGPPPQGDKSRSSQSPPGKPQGP--------PPQGGNQPQG 232
Query: 556 PPRQPFLPGPGQPFLPTHTQPNL-QGPLHPPLP----------------PPHQPQ--PQQ 596
PP P PG+P P N QGP P P PP +PQ PQQ
Sbjct: 233 PP-----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQ 287
Query: 597 ----PQQQPPPQHQPPHQPPHQPPPQHQPPPQHP----PQHPPQ 632
PQ PPP P QP P Q Q PP+ P P PPQ
Sbjct: 288 EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 90.9 bits (224), Expect = 6e-18
Identities = 92/306 (30%), Positives = 109/306 (35%), Gaps = 40/306 (13%)
Query: 407 PSQPRPAVG--PQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLG 464
P P P G PQ P PP PQ GP P ++P P + + PPP D+
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQ---GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
Query: 465 VSGEPRFPSHLFLEQ-RSPPPPP-----PPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQ 518
G+P+ P Q + PPPPP PPP N P P P GP QG
Sbjct: 93 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNR----PQGPPPPGKPQGPP--PQGD 146
Query: 519 QPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNL 578
+ PR P +P PP Q G+ P PP +P P P P
Sbjct: 147 KSRSPRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGKKP------- 190
Query: 579 QGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHP--PQHQHH 636
QGP PPP +PQ PQ Q P P PPPQ PQ PP P PQ
Sbjct: 191 QGP-----PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245
Query: 637 HHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696
+ PPPP P P + PQ++G P Q
Sbjct: 246 QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 305
Query: 697 QMQPTA 702
P A
Sbjct: 306 PQAPPA 311
Score = 73.2 bits (178), Expect = 1e-12
Identities = 79/266 (29%), Positives = 96/266 (36%), Gaps = 29/266 (10%)
Query: 465 VSGEPRFPSHLFLEQRSPPPPP------PPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQ 518
++G P+ PS + PPPP PPP N P P P GP QG
Sbjct: 32 IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK----PQGPPPPGKPQGPP--PQGD 85
Query: 519 QPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPP-----RQPFLPGPGQPFLPTH 573
+ PR P +P Q P P G P +P PP R P PG+P P
Sbjct: 86 KSRSPRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143
Query: 574 TQPNLQGPLHPPLPPPHQPQPQ---QPQQQPPPQHQPPHQPPH-QPPPQHQPPPQHPPQH 629
+ P PP P P PQ QPQ PPP +P PP PQ PPP P
Sbjct: 144 QGDKSRSPRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP 202
Query: 630 PPQHQHHHHHHHLSVPP--PPLMPMSQPQF---RPHVQTAQPQASSSRMQCPQRQGLRHN 684
PPQ P PP +QPQ P P ++ Q P G
Sbjct: 203 PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 262
Query: 685 TTSQNVSKRPMQQMQPTAPRNSNLRE 710
+Q SK + P P+ +E
Sbjct: 263 PPAQGGSKSQSARSPPGKPQGPPQQE 288
Score = 45.1 bits (105), Expect = 4e-04
Identities = 56/201 (27%), Positives = 73/201 (36%), Gaps = 21/201 (10%)
Query: 576 PNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQ-PPPQ----HPPQHP 630
P+ QG P PPP P +PQ PP P PP PP + Q PPPQ P+ P
Sbjct: 39 PSPQGGNKPQGPPP---PPGKPQGPPPQGGNKPQGPP--PPGKPQGPPPQGDKSRSPRSP 93
Query: 631 PQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQA--SSSRMQCPQRQGLRHNTTSQ 688
P + P P P +PQ P +PQ + Q P QG + +
Sbjct: 94 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS--- 150
Query: 689 NVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVA 748
+ P + Q P+ N + P P + + P P PP +
Sbjct: 151 --PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQG-D 207
Query: 749 GSRSSQGKTEVKVKPASPVAQ 769
SRSSQ KP P Q
Sbjct: 208 KSRSSQSPPG---KPQGPPPQ 225
Score = 35.8 bits (81), Expect = 0.25
Identities = 34/106 (32%), Positives = 41/106 (38%), Gaps = 15/106 (14%)
Query: 289 GDQRRESTERGRMKDHRPALLPTQPPVVPQAPPP----PPPPPQQQPIRSLFQPQPLQPL 344
GD+ R S + +P P Q PQ PPP P PP Q + P P +P
Sbjct: 206 GDKSRSS----QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 261
Query: 345 LP-----VQHPHHPSPPQGMHMPPQLETPRMMMTPPPV--TPQQPK 383
P + SPP PPQ E PPP PQQP+
Sbjct: 262 GPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 307
Score = 32.3 bits (72), Expect = 2.7
Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 993 GGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGPHAHSPVPPGIK 1052
GG +S P G+PQ PQ + G P G QQP PAG P PP
Sbjct: 267 GGSKSQSARSPPGKPQGPPQ--QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP--- 321
Query: 1053 SIQGIHPAK 1061
QG P++
Sbjct: 322 --QGGRPSR 328
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 95.5 bits (236), Expect = 3e-19
Identities = 115/512 (22%), Positives = 171/512 (33%), Gaps = 57/512 (11%)
Query: 292 RRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351
+ E+T +G PAL + P P P P ++P + + P P P
Sbjct: 200 KAETTTKG------PALTTPKEPT-PTTPKEPASTTPKEPTPTTIKSAPTTPKEPA---- 248
Query: 352 HPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP- 410
P+ + P+ P P P TP++P T + P P P+ P
Sbjct: 249 -PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307
Query: 411 RPAVGPQRFPGPPEFPQHTP----GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVS 466
+PA + P P + TP P P + P P + AP P P +
Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367
Query: 467 GEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER 526
P+ P+ ++ SP P P S P T+ P P T + P +E
Sbjct: 368 -TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE- 425
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPP 585
P + P P + A T P P P P P P P T P P P
Sbjct: 426 PAPTTPKEPAPT-----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480
Query: 586 LPPPHQPQ---PQQPQQQPP--PQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHH 640
P P+ P P++ P P+ P P P + P P+ P
Sbjct: 481 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 540
Query: 641 HLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
+ P P P P +P ++ + P TT + + +++ P
Sbjct: 541 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAP--------TTPKGTAPTTLKEPAP 588
Query: 701 TAPRNSNLRELPIAPSHVIEMSSSRC-----------SATPSAQVKPIVSASPPSRAVAG 749
T P+ +EL AP+ E +S+ C + T + P P G
Sbjct: 589 TTPKKPAPKEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 646
Query: 750 SRSSQGKTEVKVKPASPVAQPKEEAKTETEFP 781
+ + K P P PKE A T T+ P
Sbjct: 647 TAPTTLKEPAPTTPKKPA--PKELAPTTTKGP 676
Score = 90.5 bits (223), Expect = 8e-18
Identities = 111/496 (22%), Positives = 160/496 (32%), Gaps = 61/496 (12%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPV----QHPHHPSPPQGMHM 361
PA T+ P P P P P ++P + + P P P + P +P +
Sbjct: 262 PAPTTTKEPA-PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 320
Query: 362 PPQLETPRMMMTPPPVT----PQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ 417
P+ TP P P T P PK K TP + P P +P P +
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE 379
Query: 418 RFPGPPE---------FPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE 468
P P+ P T P P + P P + P P ++P
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP-----KEPSPTTTKEP----APTT 430
Query: 469 PRFPSHLFLEQRSPPPPPPP-PTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER- 526
P+ P+ ++ +P P P PT P T+ P P T PA P P+E
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-------PTTPKETA 483
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586
P P P TT + P P P P P T P P P
Sbjct: 484 PTTPKKLTP--------------TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529
Query: 587 PPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPP 646
P P P+ P P P +P P +P P P + P L P
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 587
Query: 647 PPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNS 706
P P+ T +P +++ P TT + + ++ PT P+ +
Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647
Query: 707 NLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP 766
AP+ + E + + ++ P + P S + K P P
Sbjct: 648 -------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 700
Query: 767 V-AQPKEEAKTETEFP 781
PK+ A T E P
Sbjct: 701 APTTPKKPAPTTPETP 716
Score = 73.9 bits (180), Expect = 8e-13
Identities = 102/497 (20%), Positives = 159/497 (31%), Gaps = 38/497 (7%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP-HHPSPPQGMHMPPQ 364
P+ T+ P P P P++ + +P P P P P+P P
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 365 LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQV-------PLLPVPSQPRPAVGPQ 417
TP +TP P+ + K TP ++ P P +P P
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537
Query: 418 RFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE--PRFPSHL 475
P P+ P T P + P + AP P+ P L P+ P+
Sbjct: 538 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 597
Query: 476 FLEQRSPPPPP------PPPTLLNSSHPVPTQSPLPFTQPGPA-FNQQGQQPVFPRERPV 528
L + P P PT + P + P P T PA +G P +E P
Sbjct: 598 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PA 656
Query: 529 RPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPPLP 587
+ P P + + G +T P P P P P P T P P P P
Sbjct: 657 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 716
Query: 588 PPHQPQPQQP--QQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
PP + P ++P H+ P + P +P P+ P + +
Sbjct: 717 PPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTPAATK 774
Query: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ----QMQPT 701
P ++T +++ + TT ++ Q Q T
Sbjct: 775 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 834
Query: 702 AP-RNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVK 760
P + + L+ +AP ++ + T KP +A P RA ++
Sbjct: 835 TPFKITTLKTTTLAPK---VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP------ 885
Query: 761 VKPASPVAQPKEEAKTE 777
KP P PK+ T+
Sbjct: 886 -KPQKPTKAPKKPTSTK 901
Score = 61.6 bits (148), Expect = 4e-09
Identities = 79/364 (21%), Positives = 119/364 (32%), Gaps = 50/364 (13%)
Query: 430 PGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPP 489
P P + ++ P L + P P ++P S P+ P+ ++ P P P
Sbjct: 197 PTPKAETTTKGPALTTPKE---PTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAP 249
Query: 490 TLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSA 549
T S+ P + P P T PA P P+E P P +P
Sbjct: 250 TTTKSA-PTTPKEPAPTTTKEPA-------PTTPKE---------PAPTTT---KEPAPT 289
Query: 550 TTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPP----PQH 605
TT+ P P P P P P T P P P P P P+ P + P P+
Sbjct: 290 TTKS--APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 347
Query: 606 QPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQ 665
P P P + P P+ P P P S P T +
Sbjct: 348 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP------TTTK 401
Query: 666 PQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR----NSNLRELPIAPSHVIEM 721
A ++ P TT++ + ++ PT P+ + P P
Sbjct: 402 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 461
Query: 722 SSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP----VAQPKEEAKTE 777
++ + + T + P +P A + T K+ P +P P+E A T
Sbjct: 462 TTKKPAPTTPKEPAP---TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 518
Query: 778 TEFP 781
E P
Sbjct: 519 PEEP 522
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 95.5 bits (236), Expect = 3e-19
Identities = 115/512 (22%), Positives = 171/512 (33%), Gaps = 57/512 (11%)
Query: 292 RRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351
+ E+T +G PAL + P P P P ++P + + P P P
Sbjct: 241 KAETTTKG------PALTTPKEPT-PTTPKEPASTTPKEPTPTTIKSAPTTPKEPA---- 289
Query: 352 HPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP- 410
P+ + P+ P P P TP++P T + P P P+ P
Sbjct: 290 -PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348
Query: 411 RPAVGPQRFPGPPEFPQHTP----GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVS 466
+PA + P P + TP P P + P P + AP P P +
Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408
Query: 467 GEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER 526
P+ P+ ++ SP P P S P T+ P P T + P +E
Sbjct: 409 -TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE- 466
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPP 585
P + P P + A T P P P P P P P T P P P
Sbjct: 467 PAPTTPKEPAPT-----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521
Query: 586 LPPPHQPQ---PQQPQQQPP--PQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHH 640
P P+ P P++ P P+ P P P + P P+ P
Sbjct: 522 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 581
Query: 641 HLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
+ P P P P +P ++ + P TT + + +++ P
Sbjct: 582 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAP--------TTPKGTAPTTLKEPAP 629
Query: 701 TAPRNSNLRELPIAPSHVIEMSSSRC-----------SATPSAQVKPIVSASPPSRAVAG 749
T P+ +EL AP+ E +S+ C + T + P P G
Sbjct: 630 TTPKKPAPKEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 687
Query: 750 SRSSQGKTEVKVKPASPVAQPKEEAKTETEFP 781
+ + K P P PKE A T T+ P
Sbjct: 688 TAPTTLKEPAPTTPKKPA--PKELAPTTTKGP 717
Score = 90.5 bits (223), Expect = 8e-18
Identities = 111/496 (22%), Positives = 160/496 (32%), Gaps = 61/496 (12%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPV----QHPHHPSPPQGMHM 361
PA T+ P P P P P ++P + + P P P + P +P +
Sbjct: 303 PAPTTTKEPA-PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 361
Query: 362 PPQLETPRMMMTPPPVT----PQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ 417
P+ TP P P T P PK K TP + P P +P P +
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE 420
Query: 418 RFPGPPE---------FPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE 468
P P+ P T P P + P P + P P ++P
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP-----KEPSPTTTKEP----APTT 471
Query: 469 PRFPSHLFLEQRSPPPPPPP-PTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER- 526
P+ P+ ++ +P P P PT P T+ P P T PA P P+E
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-------PTTPKETA 524
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586
P P P TT + P P P P P T P P P
Sbjct: 525 PTTPKKLTP--------------TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570
Query: 587 PPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPP 646
P P P+ P P P +P P +P P P + P L P
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 628
Query: 647 PPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNS 706
P P+ T +P +++ P TT + + ++ PT P+ +
Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688
Query: 707 NLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP 766
AP+ + E + + ++ P + P S + K P P
Sbjct: 689 -------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 741
Query: 767 V-AQPKEEAKTETEFP 781
PK+ A T E P
Sbjct: 742 APTTPKKPAPTTPETP 757
Score = 73.9 bits (180), Expect = 8e-13
Identities = 102/497 (20%), Positives = 159/497 (31%), Gaps = 38/497 (7%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP-HHPSPPQGMHMPPQ 364
P+ T+ P P P P++ + +P P P P P+P P
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 365 LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQV-------PLLPVPSQPRPAVGPQ 417
TP +TP P+ + K TP ++ P P +P P
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578
Query: 418 RFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE--PRFPSHL 475
P P+ P T P + P + AP P+ P L P+ P+
Sbjct: 579 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 638
Query: 476 FLEQRSPPPPP------PPPTLLNSSHPVPTQSPLPFTQPGPA-FNQQGQQPVFPRERPV 528
L + P P PT + P + P P T PA +G P +E P
Sbjct: 639 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PA 697
Query: 529 RPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPPLP 587
+ P P + + G +T P P P P P P T P P P P
Sbjct: 698 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 757
Query: 588 PPHQPQPQQP--QQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
PP + P ++P H+ P + P +P P+ P + +
Sbjct: 758 PPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTPAATK 815
Query: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ----QMQPT 701
P ++T +++ + TT ++ Q Q T
Sbjct: 816 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 875
Query: 702 AP-RNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVK 760
P + + L+ +AP ++ + T KP +A P RA ++
Sbjct: 876 TPFKITTLKTTTLAPK---VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP------ 926
Query: 761 VKPASPVAQPKEEAKTE 777
KP P PK+ T+
Sbjct: 927 -KPQKPTKAPKKPTSTK 942
Score = 61.6 bits (148), Expect = 4e-09
Identities = 79/364 (21%), Positives = 119/364 (32%), Gaps = 50/364 (13%)
Query: 430 PGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPP 489
P P + ++ P L + P P ++P S P+ P+ ++ P P P
Sbjct: 238 PTPKAETTTKGPALTTPKE---PTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAP 290
Query: 490 TLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSA 549
T S+ P + P P T PA P P+E P P +P
Sbjct: 291 TTTKSA-PTTPKEPAPTTTKEPA-------PTTPKE---------PAPTTT---KEPAPT 330
Query: 550 TTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPP----PQH 605
TT+ P P P P P P T P P P P P P+ P + P P+
Sbjct: 331 TTKS--APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 388
Query: 606 QPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQ 665
P P P + P P+ P P P S P T +
Sbjct: 389 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP------TTTK 442
Query: 666 PQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR----NSNLRELPIAPSHVIEM 721
A ++ P TT++ + ++ PT P+ + P P
Sbjct: 443 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 502
Query: 722 SSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP----VAQPKEEAKTE 777
++ + + T + P +P A + T K+ P +P P+E A T
Sbjct: 503 TTKKPAPTTPKEPAP---TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 778 TEFP 781
E P
Sbjct: 560 PEEP 563
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 95.5 bits (236), Expect = 3e-19
Identities = 115/512 (22%), Positives = 171/512 (33%), Gaps = 57/512 (11%)
Query: 292 RRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351
+ E+T +G PAL + P P P P ++P + + P P P
Sbjct: 293 KAETTTKG------PALTTPKEPT-PTTPKEPASTTPKEPTPTTIKSAPTTPKEPA---- 341
Query: 352 HPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP- 410
P+ + P+ P P P TP++P T + P P P+ P
Sbjct: 342 -PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400
Query: 411 RPAVGPQRFPGPPEFPQHTP----GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVS 466
+PA + P P + TP P P + P P + AP P P +
Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460
Query: 467 GEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER 526
P+ P+ ++ SP P P S P T+ P P T + P +E
Sbjct: 461 -TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE- 518
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPP 585
P + P P + A T P P P P P P P T P P P
Sbjct: 519 PAPTTPKEPAPT-----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 573
Query: 586 LPPPHQPQ---PQQPQQQPP--PQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHH 640
P P+ P P++ P P+ P P P + P P+ P
Sbjct: 574 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 633
Query: 641 HLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
+ P P P P +P ++ + P TT + + +++ P
Sbjct: 634 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAP--------TTPKGTAPTTLKEPAP 681
Query: 701 TAPRNSNLRELPIAPSHVIEMSSSRC-----------SATPSAQVKPIVSASPPSRAVAG 749
T P+ +EL AP+ E +S+ C + T + P P G
Sbjct: 682 TTPKKPAPKEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 739
Query: 750 SRSSQGKTEVKVKPASPVAQPKEEAKTETEFP 781
+ + K P P PKE A T T+ P
Sbjct: 740 TAPTTLKEPAPTTPKKPA--PKELAPTTTKGP 769
Score = 90.5 bits (223), Expect = 8e-18
Identities = 111/496 (22%), Positives = 160/496 (32%), Gaps = 61/496 (12%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPV----QHPHHPSPPQGMHM 361
PA T+ P P P P P ++P + + P P P + P +P +
Sbjct: 355 PAPTTTKEPA-PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 413
Query: 362 PPQLETPRMMMTPPPVT----PQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ 417
P+ TP P P T P PK K TP + P P +P P +
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE 472
Query: 418 RFPGPPE---------FPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE 468
P P+ P T P P + P P + P P ++P
Sbjct: 473 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP-----KEPSPTTTKEP----APTT 523
Query: 469 PRFPSHLFLEQRSPPPPPPP-PTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER- 526
P+ P+ ++ +P P P PT P T+ P P T PA P P+E
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-------PTTPKETA 576
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586
P P P TT + P P P P P T P P P
Sbjct: 577 PTTPKKLTP--------------TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 587 PPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPP 646
P P P+ P P P +P P +P P P + P L P
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 680
Query: 647 PPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNS 706
P P+ T +P +++ P TT + + ++ PT P+ +
Sbjct: 681 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 740
Query: 707 NLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP 766
AP+ + E + + ++ P + P S + K P P
Sbjct: 741 -------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793
Query: 767 V-AQPKEEAKTETEFP 781
PK+ A T E P
Sbjct: 794 APTTPKKPAPTTPETP 809
Score = 73.9 bits (180), Expect = 8e-13
Identities = 102/497 (20%), Positives = 159/497 (31%), Gaps = 38/497 (7%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP-HHPSPPQGMHMPPQ 364
P+ T+ P P P P++ + +P P P P P+P P
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 365 LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQV-------PLLPVPSQPRPAVGPQ 417
TP +TP P+ + K TP ++ P P +P P
Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 630
Query: 418 RFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE--PRFPSHL 475
P P+ P T P + P + AP P+ P L P+ P+
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 690
Query: 476 FLEQRSPPPPP------PPPTLLNSSHPVPTQSPLPFTQPGPA-FNQQGQQPVFPRERPV 528
L + P P PT + P + P P T PA +G P +E P
Sbjct: 691 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PA 749
Query: 529 RPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPPLP 587
+ P P + + G +T P P P P P P T P P P P
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 809
Query: 588 PPHQPQPQQP--QQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
PP + P ++P H+ P + P +P P+ P + +
Sbjct: 810 PPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTPAATK 867
Query: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ----QMQPT 701
P ++T +++ + TT ++ Q Q T
Sbjct: 868 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 927
Query: 702 AP-RNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVK 760
P + + L+ +AP ++ + T KP +A P RA ++
Sbjct: 928 TPFKITTLKTTTLAPK---VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP------ 978
Query: 761 VKPASPVAQPKEEAKTE 777
KP P PK+ T+
Sbjct: 979 -KPQKPTKAPKKPTSTK 994
Score = 61.6 bits (148), Expect = 4e-09
Identities = 79/364 (21%), Positives = 119/364 (32%), Gaps = 50/364 (13%)
Query: 430 PGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPP 489
P P + ++ P L + P P ++P S P+ P+ ++ P P P
Sbjct: 290 PTPKAETTTKGPALTTPKE---PTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAP 342
Query: 490 TLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSA 549
T S+ P + P P T PA P P+E P P +P
Sbjct: 343 TTTKSA-PTTPKEPAPTTTKEPA-------PTTPKE---------PAPTTT---KEPAPT 382
Query: 550 TTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPP----PQH 605
TT+ P P P P P P T P P P P P P+ P + P P+
Sbjct: 383 TTKS--APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 440
Query: 606 QPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQ 665
P P P + P P+ P P P S P T +
Sbjct: 441 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP------TTTK 494
Query: 666 PQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR----NSNLRELPIAPSHVIEM 721
A ++ P TT++ + ++ PT P+ + P P
Sbjct: 495 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 554
Query: 722 SSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP----VAQPKEEAKTE 777
++ + + T + P +P A + T K+ P +P P+E A T
Sbjct: 555 TTKKPAPTTPKEPAP---TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 611
Query: 778 TEFP 781
E P
Sbjct: 612 PEEP 615
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 95.5 bits (236), Expect = 3e-19
Identities = 115/512 (22%), Positives = 171/512 (33%), Gaps = 57/512 (11%)
Query: 292 RRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351
+ E+T +G PAL + P P P P ++P + + P P P
Sbjct: 334 KAETTTKG------PALTTPKEPT-PTTPKEPASTTPKEPTPTTIKSAPTTPKEPA---- 382
Query: 352 HPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP- 410
P+ + P+ P P P TP++P T + P P P+ P
Sbjct: 383 -PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441
Query: 411 RPAVGPQRFPGPPEFPQHTP----GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVS 466
+PA + P P + TP P P + P P + AP P P +
Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501
Query: 467 GEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER 526
P+ P+ ++ SP P P S P T+ P P T + P +E
Sbjct: 502 -TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE- 559
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPP 585
P + P P + A T P P P P P P P T P P P
Sbjct: 560 PAPTTPKEPAPT-----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 614
Query: 586 LPPPHQPQ---PQQPQQQPP--PQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHH 640
P P+ P P++ P P+ P P P + P P+ P
Sbjct: 615 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 674
Query: 641 HLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
+ P P P P +P ++ + P TT + + +++ P
Sbjct: 675 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAP--------TTPKGTAPTTLKEPAP 722
Query: 701 TAPRNSNLRELPIAPSHVIEMSSSRC-----------SATPSAQVKPIVSASPPSRAVAG 749
T P+ +EL AP+ E +S+ C + T + P P G
Sbjct: 723 TTPKKPAPKEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 780
Query: 750 SRSSQGKTEVKVKPASPVAQPKEEAKTETEFP 781
+ + K P P PKE A T T+ P
Sbjct: 781 TAPTTLKEPAPTTPKKPA--PKELAPTTTKGP 810
Score = 90.5 bits (223), Expect = 8e-18
Identities = 111/496 (22%), Positives = 160/496 (32%), Gaps = 61/496 (12%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPV----QHPHHPSPPQGMHM 361
PA T+ P P P P P ++P + + P P P + P +P +
Sbjct: 396 PAPTTTKEPA-PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 454
Query: 362 PPQLETPRMMMTPPPVT----PQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQ 417
P+ TP P P T P PK K TP + P P +P P +
Sbjct: 455 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE 513
Query: 418 RFPGPPE---------FPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE 468
P P+ P T P P + P P + P P ++P
Sbjct: 514 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP-----KEPSPTTTKEP----APTT 564
Query: 469 PRFPSHLFLEQRSPPPPPPP-PTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRER- 526
P+ P+ ++ +P P P PT P T+ P P T PA P P+E
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-------PTTPKETA 617
Query: 527 PVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586
P P P TT + P P P P P T P P P
Sbjct: 618 PTTPKKLTP--------------TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 587 PPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPP 646
P P P+ P P P +P P +P P P + P L P
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 721
Query: 647 PPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNS 706
P P+ T +P +++ P TT + + ++ PT P+ +
Sbjct: 722 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 781
Query: 707 NLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP 766
AP+ + E + + ++ P + P S + K P P
Sbjct: 782 -------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834
Query: 767 V-AQPKEEAKTETEFP 781
PK+ A T E P
Sbjct: 835 APTTPKKPAPTTPETP 850
Score = 73.9 bits (180), Expect = 8e-13
Identities = 102/497 (20%), Positives = 159/497 (31%), Gaps = 38/497 (7%)
Query: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP-HHPSPPQGMHMPPQ 364
P+ T+ P P P P++ + +P P P P P+P P
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 365 LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQV-------PLLPVPSQPRPAVGPQ 417
TP +TP P+ + K TP ++ P P +P P
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 671
Query: 418 RFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGE--PRFPSHL 475
P P+ P T P + P + AP P+ P L P+ P+
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 731
Query: 476 FLEQRSPPPPP------PPPTLLNSSHPVPTQSPLPFTQPGPA-FNQQGQQPVFPRERPV 528
L + P P PT + P + P P T PA +G P +E P
Sbjct: 732 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PA 790
Query: 529 RPALQPPGPVGILHFSQPGSATTRPFIP-PRQPFLPGPGQPFLPTHTQPNLQGPLHPPLP 587
+ P P + + G +T P P P P P P T P P P P
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 850
Query: 588 PPHQPQPQQP--QQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
PP + P ++P H+ P + P +P P+ P + +
Sbjct: 851 PPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTPAATK 908
Query: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ----QMQPT 701
P ++T +++ + TT ++ Q Q T
Sbjct: 909 PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 968
Query: 702 AP-RNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVK 760
P + + L+ +AP ++ + T KP +A P RA ++
Sbjct: 969 TPFKITTLKTTTLAPK---VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP------ 1019
Query: 761 VKPASPVAQPKEEAKTE 777
KP P PK+ T+
Sbjct: 1020 -KPQKPTKAPKKPTSTK 1035
Score = 61.6 bits (148), Expect = 4e-09
Identities = 79/364 (21%), Positives = 119/364 (32%), Gaps = 50/364 (13%)
Query: 430 PGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPP 489
P P + ++ P L + P P ++P S P+ P+ ++ P P P
Sbjct: 331 PTPKAETTTKGPALTTPKE---PTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAP 383
Query: 490 TLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSA 549
T S+ P + P P T PA P P+E P P +P
Sbjct: 384 TTTKSA-PTTPKEPAPTTTKEPA-------PTTPKE---------PAPTTT---KEPAPT 423
Query: 550 TTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPP----PQH 605
TT+ P P P P P P T P P P P P P+ P + P P+
Sbjct: 424 TTKS--APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 481
Query: 606 QPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQ 665
P P P + P P+ P P P S P T +
Sbjct: 482 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP------TTTK 535
Query: 666 PQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR----NSNLRELPIAPSHVIEM 721
A ++ P TT++ + ++ PT P+ + P P
Sbjct: 536 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 595
Query: 722 SSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASP----VAQPKEEAKTE 777
++ + + T + P +P A + T K+ P +P P+E A T
Sbjct: 596 TTKKPAPTTPKEPAP---TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 652
Query: 778 TEFP 781
E P
Sbjct: 653 PEEP 656
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 94.7 bits (234), Expect = 4e-19
Identities = 121/454 (26%), Positives = 152/454 (33%), Gaps = 131/454 (28%)
Query: 276 GGRRG-GPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRS 334
GG G G L G+ R + RP LLP P PP P + P+
Sbjct: 95 GGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-- 152
Query: 335 LFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTP---PPVTPQQPKNIHINPHF 391
P P H P PQ MPP P + P PP P P+ I +PH
Sbjct: 153 ---PSP-------GHRSGPPEPQRNRMPP--PRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200
Query: 392 KGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFP------------QHTPGPVPNSFSQ 439
+G+ PVP PR P P PP FP + +P + FS
Sbjct: 201 RGSP---------PVPGGPRQ---PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 440 PPRLP------LQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLN 493
P LP L D+ PPPP P + + + PPPPP N
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRP---------------SIHREAVPPPPPQ----N 289
Query: 494 SSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRP 553
+ PVP + P P+ + Q P P RP P L P S G+ T P
Sbjct: 290 NKPPVP-------STPRPSASSQAPPPPPPPSRPGPPPLPP---------SSSGNDET-P 332
Query: 554 FIPPRQ-------PFLPGPG-----------QPFLPTHTQPNLQGPLHPPLP-----PPH 590
+P R P LP PG +P P P GPL PP P
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392
Query: 591 QPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPP---------------QHQH 635
+ P PQ P P P P +P PP PP + +
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Query: 636 HHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQAS 669
+ H +S PPP P+VQT + S
Sbjct: 453 RFYFHPISDLPPP---------EPYVQTTKSYPS 477
Score = 83.6 bits (205), Expect = 1e-15
Identities = 85/310 (27%), Positives = 109/310 (35%), Gaps = 65/310 (20%)
Query: 269 GRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQ 328
GR+ G R GP +R RM RP + ++P +P P P P Q
Sbjct: 148 GRFPVPSPGHRSGP-----------PEPQRNRMPPPRPDV-GSKPDSIPPPVPSTPRPIQ 195
Query: 329 QQPIRSLFQPQPLQPLLPVQHPHHPSPPQGM---------------------HMPPQLET 367
P P P P P P P P + PP T
Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255
Query: 368 PRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQ 427
P + P P P + H + P Q PVPS PRP+ Q P PP +
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Query: 428 HTPGPVPNSFS---QPPRLPLQD---------------QWRAPPPPQDRDPFFLGVSGEP 469
P P+P S S + PRLP ++ PPPP +R P
Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--------- 366
Query: 470 RFPSHLFLEQRSPPPPPPPPTLLN--SSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERP 527
P RS P PPPPP N +S +P LP ++ G + G +P P +RP
Sbjct: 367 --PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP-SRSGVDSPRSGPRPPLPPDRP 423
Query: 528 VRPALQPPGP 537
A PP P
Sbjct: 424 SAGAPPPPPP 433
Score = 79.0 bits (193), Expect = 3e-14
Identities = 118/418 (28%), Positives = 152/418 (36%), Gaps = 95/418 (22%)
Query: 402 PLLP-----VPSQP-RPAVGPQRFP--------GPPEFPQHT--PGPVPNSFSQPPRLPL 445
PLLP ++P P GP RFP GPPE PQ P P P+ S+P +P
Sbjct: 127 PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE-PQRNRMPPPRPDVGSKPDSIP- 184
Query: 446 QDQWRAPPPPQDRDPFFLG---VSGEPRFPSHLFLEQRSPPPPPPP-------------- 488
+ P P P G V G PR P SP P PPP
Sbjct: 185 -PPVPSTPRPIQSSPHNRGSPPVPGGPRQP--------SPGPTPPPFPGNRGTALGGGSI 235
Query: 489 -PTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFP---RERPVRPALQPPGPVGILHFS 544
+ L+SS P + PLP T P A + + P P R R A+ PP P +
Sbjct: 236 RQSPLSSSSPFSNRPPLPPT-PSRALDDKPPPPPPPVGNRPSIHREAVPPPPP---QNNK 291
Query: 545 QPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPP---HQPQPQQPQQ-- 599
P +T RP + P P P P+ GP PPLPP + P+ PQ+
Sbjct: 292 PPVPSTPRPSASSQAPPPPPP----------PSRPGP--PPLPPSSSGNDETPRLPQRNL 339
Query: 600 ----QPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQP 655
PP P P PPP +PPP P + PP +PPPP P+S+
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPP--PVRDPPGRSG-------PLPPPP--PVSRN 388
Query: 656 QFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAP 715
A PQ S R G R RP P P ++++R
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPD----RPSAGAPPPPPPSTSIRN-GFQD 443
Query: 716 SHVIEMSSSRCSATPSAQVKP------IVSASPPSRAVAGSRSSQGKTEVKVKPASPV 767
S + SR P + + P + P A SRS + E P P+
Sbjct: 444 SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501
Score = 45.4 bits (106), Expect = 3e-04
Identities = 59/226 (26%), Positives = 75/226 (33%), Gaps = 21/226 (9%)
Query: 534 PPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQ 593
PPG G+ P +T R G P LP + P PP P P
Sbjct: 97 PPGLGGLFQAGMPKLRSTAN----RDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 594 PQQPQQQPPPQHQPPHQPPHQPPPQHQP---PPQHPPQHPPQHQHHHHHHHLSVPPPPLM 650
P + PP+ Q PP +P +P PP P P H+ VP P
Sbjct: 153 PSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212
Query: 651 PM---SQPQFRPHVQTA--------QPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQ 699
P + P F + TA P +SSS R L T S+ + +P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS--NRPPL-PPTPSRALDDKPPPPPP 269
Query: 700 PTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSR 745
P R S RE P + PSA + PPSR
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Score = 34.3 bits (77), Expect = 0.71
Identities = 59/233 (25%), Positives = 75/233 (32%), Gaps = 22/233 (9%)
Query: 838 PPPAEQEEQALSPSPTN-------GNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKT 890
PPP + + SP N G P P PG NR S Q
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG---SIRQSPL 240
Query: 891 SNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHK-VLPIKPADVEEPAVPQTPR- 948
S+ P S +AL P +H+ +P P +P VP TPR
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 949 VASIQGRPQDTKPGVKRTVTHRTNSGGGD-GPHISSKVRVIKLSGGGGESDGFFHPEGQP 1007
AS Q P P +S G D P + + + S S G P
Sbjct: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP---- 356
Query: 1008 QRLPQPP-EVGPQPARKVTLTRGGLQQPPHLPAGPHAHSPVP--PGIKSIQGI 1057
LP PP E P P R G L PP + +P P + S G+
Sbjct: 357 --LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 94.7 bits (234), Expect = 4e-19
Identities = 121/454 (26%), Positives = 152/454 (33%), Gaps = 131/454 (28%)
Query: 276 GGRRG-GPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRS 334
GG G G L G+ R + RP LLP P PP P + P+
Sbjct: 95 GGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-- 152
Query: 335 LFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTP---PPVTPQQPKNIHINPHF 391
P P H P PQ MPP P + P PP P P+ I +PH
Sbjct: 153 ---PSP-------GHRSGPPEPQRNRMPP--PRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200
Query: 392 KGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFP------------QHTPGPVPNSFSQ 439
+G+ PVP PR P P PP FP + +P + FS
Sbjct: 201 RGSP---------PVPGGPRQ---PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 440 PPRLP------LQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLN 493
P LP L D+ PPPP P + + + PPPPP N
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRP---------------SIHREAVPPPPPQ----N 289
Query: 494 SSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRP 553
+ PVP + P P+ + Q P P RP P L P S G+ T P
Sbjct: 290 NKPPVP-------STPRPSASSQAPPPPPPPSRPGPPPLPP---------SSSGNDET-P 332
Query: 554 FIPPRQ-------PFLPGPG-----------QPFLPTHTQPNLQGPLHPPLP-----PPH 590
+P R P LP PG +P P P GPL PP P
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392
Query: 591 QPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPP---------------QHQH 635
+ P PQ P P P P +P PP PP + +
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Query: 636 HHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQAS 669
+ H +S PPP P+VQT + S
Sbjct: 453 RFYFHPISDLPPP---------EPYVQTTKSYPS 477
Score = 83.6 bits (205), Expect = 1e-15
Identities = 85/310 (27%), Positives = 109/310 (35%), Gaps = 65/310 (20%)
Query: 269 GRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQ 328
GR+ G R GP +R RM RP + ++P +P P P P Q
Sbjct: 148 GRFPVPSPGHRSGP-----------PEPQRNRMPPPRPDV-GSKPDSIPPPVPSTPRPIQ 195
Query: 329 QQPIRSLFQPQPLQPLLPVQHPHHPSPPQGM---------------------HMPPQLET 367
P P P P P P P P + PP T
Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255
Query: 368 PRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQ 427
P + P P P + H + P Q PVPS PRP+ Q P PP +
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Query: 428 HTPGPVPNSFS---QPPRLPLQD---------------QWRAPPPPQDRDPFFLGVSGEP 469
P P+P S S + PRLP ++ PPPP +R P
Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPP--------- 366
Query: 470 RFPSHLFLEQRSPPPPPPPPTLLN--SSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERP 527
P RS P PPPPP N +S +P LP ++ G + G +P P +RP
Sbjct: 367 --PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP-SRSGVDSPRSGPRPPLPPDRP 423
Query: 528 VRPALQPPGP 537
A PP P
Sbjct: 424 SAGAPPPPPP 433
Score = 79.0 bits (193), Expect = 3e-14
Identities = 118/418 (28%), Positives = 152/418 (36%), Gaps = 95/418 (22%)
Query: 402 PLLP-----VPSQP-RPAVGPQRFP--------GPPEFPQHT--PGPVPNSFSQPPRLPL 445
PLLP ++P P GP RFP GPPE PQ P P P+ S+P +P
Sbjct: 127 PLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE-PQRNRMPPPRPDVGSKPDSIP- 184
Query: 446 QDQWRAPPPPQDRDPFFLG---VSGEPRFPSHLFLEQRSPPPPPPP-------------- 488
+ P P P G V G PR P SP P PPP
Sbjct: 185 -PPVPSTPRPIQSSPHNRGSPPVPGGPRQP--------SPGPTPPPFPGNRGTALGGGSI 235
Query: 489 -PTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFP---RERPVRPALQPPGPVGILHFS 544
+ L+SS P + PLP T P A + + P P R R A+ PP P +
Sbjct: 236 RQSPLSSSSPFSNRPPLPPT-PSRALDDKPPPPPPPVGNRPSIHREAVPPPPP---QNNK 291
Query: 545 QPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPP---HQPQPQQPQQ-- 599
P +T RP + P P P P+ GP PPLPP + P+ PQ+
Sbjct: 292 PPVPSTPRPSASSQAPPPPPP----------PSRPGP--PPLPPSSSGNDETPRLPQRNL 339
Query: 600 ----QPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQP 655
PP P P PPP +PPP P + PP +PPPP P+S+
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPP--PVRDPPGRSG-------PLPPPP--PVSRN 388
Query: 656 QFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAP 715
A PQ S R G R RP P P ++++R
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPD----RPSAGAPPPPPPSTSIRN-GFQD 443
Query: 716 SHVIEMSSSRCSATPSAQVKP------IVSASPPSRAVAGSRSSQGKTEVKVKPASPV 767
S + SR P + + P + P A SRS + E P P+
Sbjct: 444 SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501
Score = 45.4 bits (106), Expect = 3e-04
Identities = 59/226 (26%), Positives = 75/226 (33%), Gaps = 21/226 (9%)
Query: 534 PPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQ 593
PPG G+ P +T R G P LP + P PP P P
Sbjct: 97 PPGLGGLFQAGMPKLRSTAN----RDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 594 PQQPQQQPPPQHQPPHQPPHQPPPQHQP---PPQHPPQHPPQHQHHHHHHHLSVPPPPLM 650
P + PP+ Q PP +P +P PP P P H+ VP P
Sbjct: 153 PSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212
Query: 651 PM---SQPQFRPHVQTA--------QPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQ 699
P + P F + TA P +SSS R L T S+ + +P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS--NRPPL-PPTPSRALDDKPPPPPP 269
Query: 700 PTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSR 745
P R S RE P + PSA + PPSR
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Score = 34.3 bits (77), Expect = 0.71
Identities = 59/233 (25%), Positives = 75/233 (32%), Gaps = 22/233 (9%)
Query: 838 PPPAEQEEQALSPSPTN-------GNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKT 890
PPP + + SP N G P P PG NR S Q
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG---SIRQSPL 240
Query: 891 SNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHK-VLPIKPADVEEPAVPQTPR- 948
S+ P S +AL P +H+ +P P +P VP TPR
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 949 VASIQGRPQDTKPGVKRTVTHRTNSGGGD-GPHISSKVRVIKLSGGGGESDGFFHPEGQP 1007
AS Q P P +S G D P + + + S S G P
Sbjct: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP---- 356
Query: 1008 QRLPQPP-EVGPQPARKVTLTRGGLQQPPHLPAGPHAHSPVP--PGIKSIQGI 1057
LP PP E P P R G L PP + +P P + S G+
Sbjct: 357 --LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 94.0 bits (232), Expect = 8e-19
Identities = 176/706 (24%), Positives = 250/706 (35%), Gaps = 170/706 (24%)
Query: 14 GDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQSDLSDEELNDD--- 70
G++D + E + A+E+ + E +DD + SD DE NDD
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDD-----------DDSDDRDESENDDEDT 1081
Query: 71 LLQSDNEDEENFSSQGVTISLNATSGMVTS---------FELSDNTNDQSGEQESEY--- 118
L +E +E S + T+S+ + TS FE S ++ S E E E
Sbjct: 1082 ALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAR 1141
Query: 119 --EQEQGEDELVYHKSDGSELYTQEYPEEGQYEGHEAELTEDQIEYVEEPEEEQLYTDEV 176
E+E+ E+E+V +S S PE+ + +G EA L P + L +E
Sbjct: 1142 EEEEEEEEEEMVAEESMASA-----GPEDFEQDGEEAALAPG------APAVDSLGMEEE 1190
Query: 177 LDIEINEPLDEFTGGM-ETLELQKDIKEESDEEEEDDEESGRLRFKTERKEGTIIRLSDV 235
+DIE E M + L ++E +D E +E +EG ++ LS
Sbjct: 1191 VDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPG-------LSQEGAML-LS-- 1240
Query: 236 TRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRES 295
PE EA+ L ER +H
Sbjct: 1241 -------PEPPAKEVEARPPL--SPERAPEHDL--------------------------- 1264
Query: 296 TERGRMKDHRPAL--LPTQPPVVPQAPP-PPPPPPQQQPIRSLFQPQPLQPLLPVQHPHH 352
++ P + LP QPP+ P PP PP PPP+ + + P +PL PH
Sbjct: 1265 ----EVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHT 1320
Query: 353 PSPPQGMHMPPQLET-PRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPR 411
P + ET P PP++ +P G+ + P PS
Sbjct: 1321 PGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFS------YPAPSPSL 1374
Query: 412 PAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRF 471
+ G R PG + P + S P LP+ P P RD
Sbjct: 1375 SSGGLPRTPG----RDFSFTPTFSEPSGPLLLPV-----CPLPTGRRD------ERSGPL 1419
Query: 472 PSHLFLEQRSPPPPPPP-------PTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPR 524
S + LE P P P P P +L + PT PLP P P P +
Sbjct: 1420 ASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPT--PLPPLLPAPL----ASCPPPMK 1473
Query: 525 ERPVRPALQPPGPV---GILHFSQPGSATTRPFIPPRQPFLPG-PGQPFLPTHTQP---- 576
+P RP PP + G L G+A R + LPG P P P+ P
Sbjct: 1474 RKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELL-----LLPGQPQTPVFPSTHDPRTVT 1528
Query: 577 -NLQGPLHPPLPPPHQPQPQQPQQQPP--PQHQPPHQPPHQPPPQHQPP----------- 622
+ + P PPP PQP P PP P P + +Q P + PP
Sbjct: 1529 LDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588
Query: 623 ------PQHPPQHPPQHQHHHHHHHLSVPP---PPLMPMSQPQFRP 659
+ P + PP+ +H VPP P L P QP FRP
Sbjct: 1589 YMELAKSRGPWRRPPKKRHED-----LVPPAGSPELSP-PQPLFRP 1628
Score = 77.0 bits (188), Expect = 1e-13
Identities = 97/363 (26%), Positives = 121/363 (33%), Gaps = 62/363 (17%)
Query: 306 PALLPTQPPVVPQAP--PPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHP---SPPQGMH 360
P LP P+ + P PP PPPP + +P P P P S P G
Sbjct: 434 PPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPE 493
Query: 361 MPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFP 420
P R+ M + Q+ K + + T + P+ SQ P + P
Sbjct: 494 KPHDSLDSRIEML---LKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSP-LAPFGTN 549
Query: 421 GPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFF-LGVSGEPRFPSHLFLEQ 479
P F GP P S S+P L+D P P D D LG+ P
Sbjct: 550 SQPGFR----GPTPPS-SRPSSTGLEDISPTPLPDSDEDEELDLGLGPRP---------- 594
Query: 480 RSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQP------VFPRERPVRPALQ 533
P P PP P L S + P +GQQ + E P P
Sbjct: 595 -PPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITS 653
Query: 534 PPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQ 593
P ++ + + P P P PG PPLPPP P
Sbjct: 654 ADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG----------------FPPLPPPPPPP 697
Query: 594 PQQPQ-QQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPM 652
P QP PPP PP PP P PPP P PP VPPPP++P
Sbjct: 698 PPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA--PP-----------GVPPPPILPP 744
Query: 653 SQP 655
P
Sbjct: 745 LPP 747
Score = 55.8 bits (133), Expect = 2e-07
Identities = 83/328 (25%), Positives = 105/328 (32%), Gaps = 74/328 (22%)
Query: 320 PPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQ-LETPRMMMTPPPVT 378
PPP P PP + S L L+ + P +G + +E M P+T
Sbjct: 594 PPPEPGPPDPAGLLSQTAEVALD-LVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPIT 652
Query: 379 PQQ-PKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSF 437
PK + + P V P LP+P PP FP P P P
Sbjct: 653 SADCPKPMVVTPGAAAVAAPSVLAPTLPLPP-------------PPGFP---PLPPP--- 693
Query: 438 SQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHP 497
PP PPPPQ P FP + PPPPPPPP +HP
Sbjct: 694 --PP----------PPPPQ------------PGFP----MPPPLPPPPPPPPP----AHP 721
Query: 498 VPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHF------SQPGSATT 551
T P P P P+ P P P L P V + H P S
Sbjct: 722 AVTVPPPPLPAPPGV----PPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQM 777
Query: 552 RPFIPPRQPFLPG--PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPH 609
+ + R G P PF+ G LPP P + P
Sbjct: 778 QTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLS--------NSGPG 829
Query: 610 QPPHQPPPQHQPPPQHPPQHPPQHQHHH 637
+ H PP P PP + P+ + H
Sbjct: 830 RGQHWPPLPKFDPSVPPPGYMPRQEDPH 857
Score = 47.8 bits (112), Expect = 6e-05
Identities = 65/286 (22%), Positives = 88/286 (30%), Gaps = 59/286 (20%)
Query: 519 QPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNL 578
+ V P ERP +PP PVG+ + P + L P P +P L
Sbjct: 1196 EAVAPEERPSMLD-EPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPL 1254
Query: 579 QG--------------------PLHPPLPPPHQPQPQQPQQQP----------PPQHQPP 608
PL PPLPPP P+P P +P PP+
Sbjct: 1255 SPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAE 1314
Query: 609 HQPPHQP--------PPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPH 660
PPH P + P P PP LS P P P S P P
Sbjct: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPL-SGGSSGLSLSSPQVPGSPFSYPAPSPS 1373
Query: 661 VQT-----------------AQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAP 703
+ + ++P CP G R + S ++ P P
Sbjct: 1374 LSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLP-LP 1432
Query: 704 RNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAG 749
L LP+A V+ + + P P+ S PP + G
Sbjct: 1433 LPLPL-PLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPG 1477
Score = 32.7 bits (73), Expect = 2.1
Identities = 53/236 (22%), Positives = 80/236 (33%), Gaps = 49/236 (20%)
Query: 588 PPHQPQPQQPQ---QQPPPQHQPPHQ------PPHQPPPQH-QPPPQHPPQHPPQHQHHH 637
PP + QPQ PPP P P+Q P H PPP+ P
Sbjct: 366 PPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDS 425
Query: 638 HHHHLSVPPPPLMPMSQ-PQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696
+ PPPL P + +P P ++ M+ R + + P
Sbjct: 426 GEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTL 485
Query: 697 QMQPTAPRNSN--------------------LRELPIAPSHVIEMSSSRCSATPSAQVKP 736
+ P P + LRE P + + ++M S S++ S+Q+ P
Sbjct: 486 ESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLRE-PDSDTE-LQMEGSPISSS-SSQLSP 542
Query: 737 IVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKE---EAKTETEFPDEDEETRL 789
+ A G+ S G P P ++P E + T PD DE+ L
Sbjct: 543 L--------APFGTNSQPGFR----GPTPPSSRPSSTGLEDISPTPLPDSDEDEEL 586
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 93.2 bits (230), Expect = 1e-18
Identities = 99/335 (29%), Positives = 113/335 (33%), Gaps = 110/335 (32%)
Query: 396 VTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPV------PNSFSQPPRLPLQDQW 449
V+P+ PL PVP P P P P PP+ P H PGP P +F+ P +P
Sbjct: 640 VSPIPKPL-PVPVPPIPVPAPITVP-PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFG 697
Query: 450 RAPPPPQDRDPFFLGVSGEPRF-PSHL---FLEQRSPPPPPPPPTLLNSSHPVPTQ---- 501
PPP PF P F P HL FL PPPP PP + H P
Sbjct: 698 PGVPPPPPPPPFL-----RPGFNPMHLPPGFLPP-GPPPPITPPVSIPPPHTPPISIPNS 751
Query: 502 ----------------SPLPFTQPGPAFNQQGQQ----------PVFPRERPVRPALQP- 534
+P+P G N + P P P P QP
Sbjct: 752 TIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPV 811
Query: 535 ---------PGPVGILHFSQPGSATTRPFIPP--RQPFLPGPGQ---PFLPTHTQPNLQG 580
PGPV L G RP + P R P +P P P +P P
Sbjct: 812 SLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMM 871
Query: 581 PLHPP-------LPPPH-------------------------------------QPQPQQ 596
PP +PPPH Q PQQ
Sbjct: 872 HRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQ 931
Query: 597 PQQQPPPQ--HQPPHQPPHQPPPQHQPPP-QHPPQ 628
PQQQP PQ QP Q QPPP QPPP Q PQ
Sbjct: 932 PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 966
Score = 53.5 bits (127), Expect = 1e-06
Identities = 57/206 (27%), Positives = 76/206 (36%), Gaps = 26/206 (12%)
Query: 315 VVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTP 374
V P AP P PP QP+ SL Q + P P G+ P T + P
Sbjct: 794 VPPAAPTNLPTPPVTQPV-SLLGTQGVAP----------GPVIGLQAP---STGLLGARP 839
Query: 375 PPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVP 434
+ Q+P + PH + + P + P+ P P GP F PP P P
Sbjct: 840 GLIPLQRPPGMP-PPHLQRFPLMPPR-PMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPH 897
Query: 435 NSFSQPPRLP-LQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLN 493
F +P +P L P P+DRD G P+ P +Q+ P P P
Sbjct: 898 GPFVRPGGMPGLGGPGPGPGGPEDRD----GRQQPPQQP-----QQQPQPQAPQQPQQQQ 948
Query: 494 SSHPVPTQSPLPFTQPGPAFNQQGQQ 519
P P+Q P P Q F +Q
Sbjct: 949 QQQPPPSQQPPPTQQQPQQFRNDNRQ 974
Score = 50.4 bits (119), Expect = 1e-05
Identities = 50/206 (24%), Positives = 72/206 (34%), Gaps = 28/206 (13%)
Query: 572 THTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPH----------QPPHQPPPQHQP 621
+HT+P P+ PLP P P P PP PPH QPP PP P
Sbjct: 635 SHTEP--VSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIP 692
Query: 622 PPQH----PPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQ 677
PP PP PP + + +PP L P P P V P +
Sbjct: 693 PPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNST 752
Query: 678 RQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLREL---------PIAPSHVIEMSSSR--- 725
G+ +TT P+ + A N+ + P AP+++ ++
Sbjct: 753 IAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVS 812
Query: 726 CSATPSAQVKPIVSASPPSRAVAGSR 751
T P++ PS + G+R
Sbjct: 813 LLGTQGVAPGPVIGLQAPSTGLLGAR 838
Score = 46.6 bits (109), Expect = 1e-04
Identities = 71/301 (23%), Positives = 100/301 (33%), Gaps = 53/301 (17%)
Query: 353 PSPPQGMHMPPQLETPRMMMTPPPVTPQQPKN---IHINPHFKGTVVTPVQVPLLPVPSQ 409
P P + PP TP + P PQ P + + F+ T +Q L
Sbjct: 141 PPPVKVSSEPPTQATPNSV----PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 196
Query: 410 PRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQ------------- 456
P+P + P + P P + + PPP Q
Sbjct: 197 PKP-----QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFD 251
Query: 457 -DRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSP---LPFTQPGPA 512
D +P + S + + + PP P T+ ++ P P PF PG
Sbjct: 252 YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDG 311
Query: 513 FNQQGQQPVFPRERPVRPALQPPGPVGI----LHFSQPGSATTRPFIPPRQPFLPGPGQP 568
QQP + + + + P +GI +H P +PP PG
Sbjct: 312 M----QQPAYTQHQNMDQF--QPRMMGIQQDPMHHQVP--------LPPNGQM---PGFG 354
Query: 569 FLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQ 628
LPT P + P+ PP PP QP Q Q P Q PHQ Q QP Q +
Sbjct: 355 LLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQ---QEMEVEQPCIQEVKR 411
Query: 629 H 629
H
Sbjct: 412 H 412
Score = 45.1 bits (105), Expect = 4e-04
Identities = 87/352 (24%), Positives = 114/352 (32%), Gaps = 63/352 (17%)
Query: 420 PGPPEFPQHTPGP--VPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFL 477
P PP P PNS P+LP D + A F G+ L
Sbjct: 140 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQ------LFQTTQGQQL---QQIL 190
Query: 478 EQRSPPPPPPPPTLLNSS----HPVPTQSPLPFTQPGP---AFNQQGQQPVFPRERPVRP 530
+ PP P P L N+ + Q TQP AF Q+ F ++ R
Sbjct: 191 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 250
Query: 531 ALQP-PGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPP 589
P V + TT P P PT T P P PPP
Sbjct: 251 DYDDEPEAVEESKKEDTTAVTTTA---------PAAAVPPAPTATVPAAAAPAAASPPPP 301
Query: 590 HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQ-----HHHHHHHLSV 644
Q P P Q P HQ Q QP Q P HQ + +
Sbjct: 302 -----QAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 356
Query: 645 PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704
P PP PM+QP P QP +S + Q ++ ++++P QQ
Sbjct: 357 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQ------------NEPLTQKPHQQEMEV--- 401
Query: 705 NSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGK 756
E P MS +R S + SA P R+ +GSRS + +
Sbjct: 402 -----EQPCIQEVKRHMSDNRKSRSRSASRSP-----KRRRSRSGSRSRRSR 443
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/45 (53%), Positives = 27/45 (60%), Gaps = 5/45 (11%)
Query: 308 LLPTQPPVVPQAPPP-PPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351
LLPT PP P A P PP PP QQP ++ FQ Q +PL Q PH
Sbjct: 355 LLPT-PPFPPMAQPVIPPTPPVQQPFQASFQAQN-EPL--TQKPH 395
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 93.2 bits (230), Expect = 1e-18
Identities = 99/335 (29%), Positives = 113/335 (33%), Gaps = 110/335 (32%)
Query: 396 VTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPV------PNSFSQPPRLPLQDQW 449
V+P+ PL PVP P P P P PP+ P H PGP P +F+ P +P
Sbjct: 655 VSPIPKPL-PVPVPPIPVPAPITVP-PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFG 712
Query: 450 RAPPPPQDRDPFFLGVSGEPRF-PSHL---FLEQRSPPPPPPPPTLLNSSHPVPTQ---- 501
PPP PF P F P HL FL PPPP PP + H P
Sbjct: 713 PGVPPPPPPPPFL-----RPGFNPMHLPPGFLPP-GPPPPITPPVSIPPPHTPPISIPNS 766
Query: 502 ----------------SPLPFTQPGPAFNQQGQQ----------PVFPRERPVRPALQP- 534
+P+P G N + P P P P QP
Sbjct: 767 TIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPV 826
Query: 535 ---------PGPVGILHFSQPGSATTRPFIPP--RQPFLPGPGQ---PFLPTHTQPNLQG 580
PGPV L G RP + P R P +P P P +P P
Sbjct: 827 SLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMM 886
Query: 581 PLHPP-------LPPPH-------------------------------------QPQPQQ 596
PP +PPPH Q PQQ
Sbjct: 887 HRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQ 946
Query: 597 PQQQPPPQ--HQPPHQPPHQPPPQHQPPP-QHPPQ 628
PQQQP PQ QP Q QPPP QPPP Q PQ
Sbjct: 947 PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 981
Score = 53.5 bits (127), Expect = 1e-06
Identities = 57/206 (27%), Positives = 76/206 (36%), Gaps = 26/206 (12%)
Query: 315 VVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTP 374
V P AP P PP QP+ SL Q + P P G+ P T + P
Sbjct: 809 VPPAAPTNLPTPPVTQPV-SLLGTQGVAP----------GPVIGLQAP---STGLLGARP 854
Query: 375 PPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVP 434
+ Q+P + PH + + P + P+ P P GP F PP P P
Sbjct: 855 GLIPLQRPPGMP-PPHLQRFPLMPPR-PMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPH 912
Query: 435 NSFSQPPRLP-LQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLN 493
F +P +P L P P+DRD G P+ P +Q+ P P P
Sbjct: 913 GPFVRPGGMPGLGGPGPGPGGPEDRD----GRQQPPQQP-----QQQPQPQAPQQPQQQQ 963
Query: 494 SSHPVPTQSPLPFTQPGPAFNQQGQQ 519
P P+Q P P Q F +Q
Sbjct: 964 QQQPPPSQQPPPTQQQPQQFRNDNRQ 989
Score = 50.4 bits (119), Expect = 1e-05
Identities = 50/206 (24%), Positives = 72/206 (34%), Gaps = 28/206 (13%)
Query: 572 THTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPH----------QPPHQPPPQHQP 621
+HT+P P+ PLP P P P PP PPH QPP PP P
Sbjct: 650 SHTEP--VSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIP 707
Query: 622 PPQH----PPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQ 677
PP PP PP + + +PP L P P P V P +
Sbjct: 708 PPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNST 767
Query: 678 RQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLREL---------PIAPSHVIEMSSSR--- 725
G+ +TT P+ + A N+ + P AP+++ ++
Sbjct: 768 IAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVS 827
Query: 726 CSATPSAQVKPIVSASPPSRAVAGSR 751
T P++ PS + G+R
Sbjct: 828 LLGTQGVAPGPVIGLQAPSTGLLGAR 853
Score = 46.6 bits (109), Expect = 1e-04
Identities = 71/301 (23%), Positives = 100/301 (33%), Gaps = 53/301 (17%)
Query: 353 PSPPQGMHMPPQLETPRMMMTPPPVTPQQPKN---IHINPHFKGTVVTPVQVPLLPVPSQ 409
P P + PP TP + P PQ P + + F+ T +Q L
Sbjct: 156 PPPVKVSSEPPTQATPNSV----PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211
Query: 410 PRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQ------------- 456
P+P + P + P P + + PPP Q
Sbjct: 212 PKP-----QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFD 266
Query: 457 -DRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSP---LPFTQPGPA 512
D +P + S + + + PP P T+ ++ P P PF PG
Sbjct: 267 YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDG 326
Query: 513 FNQQGQQPVFPRERPVRPALQPPGPVGI----LHFSQPGSATTRPFIPPRQPFLPGPGQP 568
QQP + + + + P +GI +H P +PP PG
Sbjct: 327 M----QQPAYTQHQNMDQF--QPRMMGIQQDPMHHQVP--------LPPNGQM---PGFG 369
Query: 569 FLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQ 628
LPT P + P+ PP PP QP Q Q P Q PHQ Q QP Q +
Sbjct: 370 LLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQ---QEMEVEQPCIQEVKR 426
Query: 629 H 629
H
Sbjct: 427 H 427
Score = 45.1 bits (105), Expect = 4e-04
Identities = 87/352 (24%), Positives = 114/352 (32%), Gaps = 63/352 (17%)
Query: 420 PGPPEFPQHTPGP--VPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFL 477
P PP P PNS P+LP D + A F G+ L
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQ------LFQTTQGQQL---QQIL 205
Query: 478 EQRSPPPPPPPPTLLNSS----HPVPTQSPLPFTQPGP---AFNQQGQQPVFPRERPVRP 530
+ PP P P L N+ + Q TQP AF Q+ F ++ R
Sbjct: 206 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 265
Query: 531 ALQP-PGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPP 589
P V + TT P P PT T P P PPP
Sbjct: 266 DYDDEPEAVEESKKEDTTAVTTTA---------PAAAVPPAPTATVPAAAAPAAASPPPP 316
Query: 590 HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQ-----HHHHHHHLSV 644
Q P P Q P HQ Q QP Q P HQ + +
Sbjct: 317 -----QAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 371
Query: 645 PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704
P PP PM+QP P QP +S + Q ++ ++++P QQ
Sbjct: 372 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQ------------NEPLTQKPHQQEMEV--- 416
Query: 705 NSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGK 756
E P MS +R S + SA P R+ +GSRS + +
Sbjct: 417 -----EQPCIQEVKRHMSDNRKSRSRSASRSP-----KRRRSRSGSRSRRSR 458
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/45 (53%), Positives = 27/45 (60%), Gaps = 5/45 (11%)
Query: 308 LLPTQPPVVPQAPPP-PPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351
LLPT PP P A P PP PP QQP ++ FQ Q +PL Q PH
Sbjct: 370 LLPT-PPFPPMAQPVIPPTPPVQQPFQASFQAQN-EPL--TQKPH 410
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 92.8 bits (229), Expect = 2e-18
Identities = 130/584 (22%), Positives = 220/584 (37%), Gaps = 119/584 (20%)
Query: 309 LPTQPPVVPQAPPP--PPPPPQQQPIRSLFQPQPLQPLLP-VQHPHHPSPPQGMHMPPQL 365
+P P P+APPP P P + P + + P P +P +P + P P P+
Sbjct: 10510 VPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEA 10569
Query: 366 ETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEF 425
P+ +PPP P+ PK + VP + PA PP+
Sbjct: 10570 IPPKPE-SPPPEVPEAPKEV--------------------VPEKKVPA-------APPKK 10601
Query: 426 PQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSP--- 482
P+ TP VP + P + + + PPP + P + P P E++ P
Sbjct: 10602 PEVTPVKVPEA---PKEVVPEKKVPVPPPKKPEVP----PTKVPEVPKVAVPEKKVPEAI 10654
Query: 483 PPPP--PPPTLLNSSHPVPTQSPLP--FTQPGPAFNQQ----GQQPVFPRERPVRPALQP 534
PP P PPP + V + P +P PA Q ++PV ++ P A +P
Sbjct: 10655 PPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP 10714
Query: 535 P-GPVGILHFSQPGSATTR-PFIPPRQPFLPGPGQPFLPTHTQP--NLQGPLHPPLPPPH 590
PV + + + P + P++P P P +P P + P P +PP
Sbjct: 10715 ELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAK 10774
Query: 591 QPQ-PQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQH--PPQHQHHHHHHHLSVPPP 647
P+ P++P + P P + PP ++ P + P+ P+ + P
Sbjct: 10775 VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE----------KPV 10824
Query: 648 PLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSN 707
P+ +P+ P +P+ + P V K+P + P P
Sbjct: 10825 PVAEEEEPEVPPPAVPEEPKKIIPEKKVP-------------VIKKP-EAPPPKEPE--- 10867
Query: 708 LRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPV 767
P VIE ++KP PP + K +VK K
Sbjct: 10868 -------PEKVIE----------KPKLKPRPPPPPP---------APPKEDVKEKIFQLK 10901
Query: 768 AQPKEEAKTETEFPDEDE---------ETRLYRLKIEEQKRLREEILKQKELRRQQQAGA 818
A PK++ + + P++ E E ++ +L E + +EE++ + LR++ +
Sbjct: 10902 AIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEE 10961
Query: 819 RKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFP 862
K E ++L + ++ PPP + E+ P+ T +P P
Sbjct: 10962 PKVE-PKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEP 11004
Score = 85.5 bits (210), Expect = 3e-16
Identities = 135/646 (20%), Positives = 228/646 (35%), Gaps = 106/646 (16%)
Query: 305 RPALLPTQPPVVPQA------------PPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHH 352
+P + PT+ P VP+A P P PPP+ P+ P P + P
Sbjct: 10545 KPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKP-E 10603
Query: 353 PSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRP 412
+P + P ++ + + PPP P+ P P +VP +P + P
Sbjct: 10604 VTPVKVPEAPKEVVPEKKVPVPPPKKPEVP---------------PTKVPEVPKVAVPEK 10648
Query: 413 AVGPQRFPGPPEF--PQHTPGPVPNSFSQPPRLPLQDQWRAPPP----------PQDRDP 460
V P+ P PE P+ P + +PP +++ A PP P+ + P
Sbjct: 10649 KV-PEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAP 10707
Query: 461 FFLGVSGE------PRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFN 514
+ E P P + E++ P P P + P + +P +
Sbjct: 10708 AVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKK 10767
Query: 515 QQGQQPVFPRERPVRPALQ--PPGPVGILHFSQPGSATTRP-FIPPRQPFLPGPGQPFLP 571
+ P E P +P L+ P PV S P P I P + P +P +P
Sbjct: 10768 PEVPPAKVP-EVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKP-VP 10825
Query: 572 THTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQH-------QPPPQ 624
+ + P PP P +P+ P+++ P +P PP +P P+ +P P
Sbjct: 10826 VAEE---EEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPP 10882
Query: 625 HPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSS----RMQCPQR-- 678
PP PP+ L P +P +PQ V+ + R P+R
Sbjct: 10883 PPPPAPPKEDVKEKIFQLKAIPKKKVP-EKPQVPEKVELTPLKVPGGEKKVRKLLPERKP 10941
Query: 679 QGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIV 738
+ + KRP ++ P+ + P P KP+
Sbjct: 10942 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE--------------PPPPKPVE 10987
Query: 739 SASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEF------PDEDEETRLYRL 792
P+ + + ++KPA P+ P+ + K E E P E E T +
Sbjct: 10988 EVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPI--- 11044
Query: 793 KIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSP 852
+ K+ E + ++ A+ K ++ + ++ P P E E + L P
Sbjct: 11045 ---AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKK------TPSPIEAERRKLRPGS 11095
Query: 853 TNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSA 898
P P + V + + + +D+ ++ S FV SSA
Sbjct: 11096 GGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTE-----SEFVGSSA 11136
Score = 85.1 bits (209), Expect = 4e-16
Identities = 133/624 (21%), Positives = 232/624 (37%), Gaps = 110/624 (17%)
Query: 354 SPPQGMHMPPQLETPRMMMT-------PPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPV 406
+PP+G + ++ P+ T PP P+ PK I + K V +VP V
Sbjct: 10438 APPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEE--KVRVPEEPRVPPTKV 10495
Query: 407 PS--QPRPAVGPQRFPGPP-EFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFL 463
P P+ V ++ P PP + P+ P VP + P + + + PPP + P
Sbjct: 10496 PEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEA---PKEVVPEKKVPVPPPKKPEVP--- 10549
Query: 464 GVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPA-FNQQGQQPVF 522
+ P P E++ P PP P +SP P P + + P
Sbjct: 10550 -PTKVPEVPKAAVPEKKVPEAIPPKP-----------ESPPPEVPEAPKEVVPEKKVPAA 10597
Query: 523 PRERP-VRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGP 581
P ++P V P P P ++ + P PP++P +P P +P P + P
Sbjct: 10598 PPKKPEVTPVKVPEAPKEVVPEKKV------PVPPPKKPEVPPTKVPEVPKVAVPEKKVP 10651
Query: 582 LHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQ---HQPPPQHPPQHPPQHQHHHH 638
+ P +P+ PP + P + + PP +P P PPQ
Sbjct: 10652 ---------EAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQ---------- 10692
Query: 639 HHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQM 698
++VPP +P + P V +P+ ++ ++ + V K+
Sbjct: 10693 ---VTVPPKKPVPEKK---APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKK----- 10741
Query: 699 QPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTE 758
P AP ++P P V+ + + +V P P + V
Sbjct: 10742 -PEAPP----AKVPEVPKEVV--PEKKVAVPKKPEVPPAKVPEVPKKPV----------- 10783
Query: 759 VKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGA 818
++ KPA PV + E E + + +E + EE+K + ++ E+
Sbjct: 10784 LEEKPAVPVPERAESPPPEV-YEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEE 10842
Query: 819 RKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLL--- 875
KK + E+ ++ APPP + E+ + P P P A +++VK ++
Sbjct: 10843 PKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPP-PPAPPKEDVKEKIFQLK 10901
Query: 876 -VKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQT---------- 924
+ + V P+ P ++ G + K K L + + P+ +
Sbjct: 10902 AIPKKKVPEKPQVPEKVELTP----LKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP 10957
Query: 925 -QPLHKVLPIKPADVEEPAVPQTP 947
+ KV P K V++PAVP+ P
Sbjct: 10958 EEEEPKVEPKKLEKVKKPAVPEPP 10981
Score = 75.5 bits (184), Expect = 3e-13
Identities = 210/1019 (20%), Positives = 357/1019 (35%), Gaps = 210/1019 (20%)
Query: 111 SGEQESEYEQEQGEDELVYHKSDGSELYTQEYPEEGQYEGHEAELTEDQIEYVEEPE--- 167
S ++E EYE+ + D + + + T+EY + +YE E E E+ EY+ EPE
Sbjct: 9738 SVQREEEYEEYEEYDYKEFEEYEP----TEEYDQYEEYEEREYERYEEHEEYITEPEKPI 9793
Query: 168 ------EEQLYT---------------DEVLDIEINEPLDEFTGGMETLELQKDIKEE-- 204
EE + T +E + + I + L + E K + EE
Sbjct: 9794 PVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLK--PPPPKVPEEPKKVFEEKI 9851
Query: 205 -----SDEEEEDDEESGRLRFKTER------------KEGTIIRLSDVTRERRNIPETLE 247
E+E+ E + ++ K +R + +R+ +V +E PE +
Sbjct: 9852 RISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELE--PEEVA 9909
Query: 248 LSAEAKAALLEF---EERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDH 304
E + E+ EE E H++ + + P++ V + R+ ++
Sbjct: 9910 FEEEVVTHVEEYLVEEEEEYIHEEEEFITE---EEVVPVIPVKVPEVPRKPVP----EEK 9962
Query: 305 RPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQ 364
+P +P + P P P P+++ + + + P + P P P + + +P
Sbjct: 9963 KPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP-- 10020
Query: 365 LETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPE 424
P+ + PP P+ PK PV +PVP+ + P + P P+
Sbjct: 10021 --VPKKVEAPPAKVPEVPKK-------------PVPEKKVPVPAPKKVEAPPAKVPEVPK 10065
Query: 425 --FPQH-TPGPVPNSFSQPPRLPLQDQWRAPPP-----PQDRDPFFLGVSGEPRFPSHLF 476
P+ P PVP PP P + R P P PQ+ + F E P
Sbjct: 10066 KLIPEEKKPTPVPKKVEAPP--PKVPKKREPVPVPVALPQEEEVLF----EEEIVPEEEV 10119
Query: 477 LEQRSPPPPPPPPTLLNSSHPVPTQSPLP--FTQPGPAFNQQGQQPVFPRERPVRPALQP 534
L + P L +P + +P + P ++ F E V P ++P
Sbjct: 10120 LPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKP 10179
Query: 535 PGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQP 594
PV T + + P++ P P +P + LP + P
Sbjct: 10180 KVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK-----RIILPKEEEVLP 10234
Query: 595 ----QQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLM 650
++P+++P + + P +PP + PP+ P + P
Sbjct: 10235 VEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVP--------------EVIKKAVPEA 10280
Query: 651 PMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRE 710
P P+ + P A S+ + P+ K P+ + AP +
Sbjct: 10281 PTPVPK-----KVEAPPAKVSK-KIPE-------------EKVPVPVQKKEAPP----AK 10317
Query: 711 LPIAPSHVIE--MSSSRCSATPSAQVKPI----VSASPPSRAVAGSRSSQGKTEVKVK-- 762
+P P V E + + A P A+ + + VS + V R E +V+
Sbjct: 10318 VPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEI 10377
Query: 763 PASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKE 822
P EE E EF + +E +L EQ R+ EE +K R + A + E
Sbjct: 10378 PEEEEFHEVEEYFEEGEFHEVEEFIKL------EQHRVEEEHRVEKVHRVIEVFEAEEVE 10431
Query: 823 LLERLAQQQQQLYAPPPPAEQEEQALSPS--PTNGNPLLPFPGAQVRQNVKNRLLVKNQD 880
+ E+ APP E E+ + P PT P P A+V + K +V +
Sbjct: 10432 VFEKPK-------APPKGPEISEKIIPPKKPPTKVVPRKE-PPAKVPEVPKK--IVVEEK 10481
Query: 881 VSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEE 940
V + P+ P+ K + L VP+ + V P K +
Sbjct: 10482 VRV----PEEPRVPPT-----------KVPEVLPPKEVVPEKKV----PVPPAKKPEAPP 10522
Query: 941 PAVPQTPRVASIQGR---PQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGES 997
P VP+ P+ + + P KP V T + +
Sbjct: 10523 PKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP---------- 10572
Query: 998 DGFFHPEGQPQRLPQ-PPEVGPQ------PARKVTLTRGGLQQPPHLPAGPHAHSPVPP 1049
PE P +P+ P EV P+ P +K +T + + P P PVPP
Sbjct: 10573 ----KPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK-EVVPEKKVPVPP 10626
Score = 74.7 bits (182), Expect = 5e-13
Identities = 189/926 (20%), Positives = 325/926 (35%), Gaps = 132/926 (14%)
Query: 198 QKDIKEESDEEEEDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALL 257
+K +K + EEE + R + ++E I RE + I E + + +A L
Sbjct: 9675 EKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPK--REPQPIKEVTIMEEKERAYTL 9732
Query: 258 EFE----ERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERG--RMKDHRPALL-P 310
E E +RE ++++ + P DQ E ER R ++H + P
Sbjct: 9733 EEEAVSVQREEEYEEYEEYDYKEFEEYEPTE---EYDQYEEYEEREYERYEEHEEYITEP 9789
Query: 311 TQP-PVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPR 369
+P PV P P P P+ P + L + P + + P P P+
Sbjct: 9790 EKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKV--------PVP-----------IPK 9830
Query: 370 MMMTPPPVTPQQPKNI---HINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGP---- 422
+ PPP P++PK + I V P VP +P+ V ++ P P
Sbjct: 9831 KLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEV 9890
Query: 423 ------PEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPP--QDRDPFFLGVSGEPRFPSH 474
PE P+ P +F + +++ + + F P P
Sbjct: 9891 APPVRVPEVPKELE-PEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVK 9949
Query: 475 LFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQ-PGPAFNQQGQQPV-FPRERPVRPAL 532
+ R P P P PVP + P + P + + PV P++ PA
Sbjct: 9950 VPEVPRKPVPEEKKPV------PVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAK 10003
Query: 533 QPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPL-------HPP 585
P P +P P P++ P P +P P + P+ PP
Sbjct: 10004 VPEVP------KKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPP 10057
Query: 586 LPPPHQPQPQQPQQ-QPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSV 644
P P+ P++ +P P + PP + P + +P P P PQ + + V
Sbjct: 10058 AKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFEEEI-V 10114
Query: 645 PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704
P ++P + + P + P+ P+ + + + + + + P
Sbjct: 10115 PEEEVLP-EEEEVLPEEEEVLPEEEE---VLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170
Query: 705 NSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGK-----TEV 759
L E+ + + T V P +PP++ + + K E
Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEE 10230
Query: 760 KVKPASPVAQPKEEAKTETEFPDED------EETRLYRLKIEEQKRLREEILKQKELRRQ 813
+V P +P+EE +E E P+E EE R+ +K + E +
Sbjct: 10231 EVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEA 10290
Query: 814 QQAGARKKELLERLAQQQQQLYAPP------PPAEQEEQALSPS-----PTNGNPLLPFP 862
A KK E++ Q+ APP P E++ L P P G +L
Sbjct: 10291 PPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEK 10350
Query: 863 -GAQVRQN--VKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTV 919
RQ VK RL ++ + + + + + + +++ L Q R
Sbjct: 10351 VSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVE 10410
Query: 920 PQSQTQPLHKVLPIKPAD----VEEP-AVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSG 974
+ + + +H+V+ + A+ E+P A P+ P ++ P+ KP K +
Sbjct: 10411 EEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPK--KPPTKVVPRKEPPAK 10468
Query: 975 GGDGPH---ISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQ---PPEVGPQPARKVTLTR 1028
+ P + KVRV + P P ++P+ P EV P+ V +
Sbjct: 10469 VPEVPKKIVVEEKVRVPE------------EPRVPPTKVPEVLPPKEVVPEKKVPVPPAK 10516
Query: 1029 GGLQQPPHLPAG-----PHAHSPVPP 1049
PP +P P PVPP
Sbjct: 10517 KPEAPPPKVPEAPKEVVPEKKVPVPP 10542
Score = 52.8 bits (125), Expect = 2e-06
Identities = 98/438 (22%), Positives = 171/438 (39%), Gaps = 80/438 (18%)
Query: 144 EEGQYEGHEAELTEDQ--IEYVEEPEEE---QLYTDEVLDIEINEPLDEFTGGMETLELQ 198
+E YE +A E + IE EEP +E + YT+ EP +++ E++
Sbjct: 9052 KEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYE------EIK 9105
Query: 199 KDIKEESDEEEEDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLE 258
+ K+E EE E+D E G+ + ER+EG + E E +++ E
Sbjct: 9106 VEAKKEVHEEWEEDFEEGQEYY--EREEG-YDEGEEEWEEAYQEREVIQVQKEV------ 9156
Query: 259 FEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQ 318
+EE + + ++ P + + ++ E T R RM++ + + T+ P V +
Sbjct: 9157 YEESHERKVPAKVPEKKA--PPPPKVIKKPVIEKIEKTSR-RMEEEKVQV--TKVPEVSK 9211
Query: 319 APPPPPPPPQQQPIRSLFQPQPLQPLLPVQH-------------PHHPSPPQGMHMP--- 362
P Q+P R+ Q + ++ +P H H + +P
Sbjct: 9212 KIVP------QKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQ 9265
Query: 363 PQLETPRMM-------MTPPPVTPQQPKN--------IHINPHFKGTVVTPVQVPLLPVP 407
++ T + + PPP P+ P+ + I + +VP PVP
Sbjct: 9266 KEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVP 9325
Query: 408 SQPRPAVGPQRFP-GPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVS 466
+ +P P++ P PP+ P+ PVP ++P+ + PP GV
Sbjct: 9326 EEKKPVPVPKKEPAAPPKVPEVPKKPVPEE-----KIPVPVAKKKEAPPAKVPEVQKGVV 9380
Query: 467 GEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQ----PGPAFNQQGQQPVF 522
E + + QR PPP P + P + P+P + P P ++PV
Sbjct: 9381 TEEKI---TIVTQREESPPPAVPEIPKKKVP-EERKPVPRKEEEVPPPPKVPALPKKPV- 9435
Query: 523 PRER---PVRPALQPPGP 537
P E+ PV A + P P
Sbjct: 9436 PEEKVAVPVPVAKKAPPP 9453
Score = 51.2 bits (121), Expect = 6e-06
Identities = 55/259 (21%), Positives = 99/259 (38%), Gaps = 50/259 (19%)
Query: 302 KDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHM 361
K+ P + +P + P+ PPPPP PP++ +FQ L+ + + P P P+ + +
Sbjct: 10864 KEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQ---LKAIPKKKVPEKPQVPEKVEL 10920
Query: 362 PPQLETP----RMMMTPPPVTPQQPKNIHI-----------NPHFKGTVVTPVQVPLLPV 406
P L+ P ++ P P+ + + + P + + V+ P +P
Sbjct: 10921 TP-LKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE 10979
Query: 407 PSQPRP---------AVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQD 457
P P+P ++ P P + P+ P +P +P P + PPP +
Sbjct: 10980 PPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA-IPLPAPEPKPKPEAEVKTIKPPPVE 11038
Query: 458 RDPF---------FLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQ 508
+P +G E + P + + P P T P P ++ +
Sbjct: 11039 PEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKT------PSPIEAERRKLR 11092
Query: 509 PGPAFNQQGQQPVFPRERP 527
PG G++P P E P
Sbjct: 11093 PGSG----GEKP--PDEAP 11105
Score = 48.1 bits (113), Expect = 5e-05
Identities = 130/684 (19%), Positives = 232/684 (33%), Gaps = 126/684 (18%)
Query: 247 ELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRP 306
E+ EAK + E E + + Q Y G G ++ ++ ++
Sbjct: 9103 EIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHE 9162
Query: 307 ALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLE 366
+P + VP+ PPPP ++P+ + ++E
Sbjct: 9163 RKVPAK---VPEKKAPPPPKVIKKPVIEKIE----------------------KTSRRME 9197
Query: 367 TPRMMMTPPP-----VTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPG 421
++ +T P + PQ+P TPVQ ++ V PAV ++
Sbjct: 9198 EEKVQVTKVPEVSKKIVPQKPSR------------TPVQEEVIEVKV---PAVHTKKMVI 9242
Query: 422 PPE---FPQHTPGPVPNSFSQ-------PPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRF 471
E F HT V + + ++ + R PPP+ P
Sbjct: 9243 SEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPK-----------VPEL 9291
Query: 472 PSHLFLEQRSPPP------PPPPPTLLNSSHPVPTQS---PLPFTQPG--PAFNQQGQQP 520
P E+ +P P PP P PVP + P+P +P P + ++P
Sbjct: 9292 PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKP 9351
Query: 521 VFPRERPVRPALQPPGPVGILHFSQPGSATTRPF-IPPRQPFLPGPGQPFLPTHTQPNLQ 579
V + PV A + P + Q G T I ++ P P P +P
Sbjct: 9352 VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIP-------- 9403
Query: 580 GPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQ---PPPQHPPQHPP----- 631
+P +P P++ ++ PPP P P +P P+ + P P PP
Sbjct: 9404 ---KKKVPEERKPVPRKEEEVPPPPKVP--ALPKKPVPEEKVAVPVPVAKKAPPPRAEVS 9458
Query: 632 -----QHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTT 686
+ + LS P + +++ + + + + R+ R
Sbjct: 9459 KKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEE 9518
Query: 687 SQNVSKRPMQQMQPTAPRNSNL----RELPIAPSHVIEMSSSRCSATPSAQVKPIVSASP 742
V++ + + L + + P+ V E + P K + P
Sbjct: 9519 EAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAK--IEEPP 9576
Query: 743 PSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLRE 802
P++ + + +V P PK+E + P+E ++ + K+ + E
Sbjct: 9577 PAKVPEAPKKIVPEKKV------PAPVPKKEKVPPPKVPEEPKKP-VPEKKVPPKVIKME 9629
Query: 803 EILKQKELRRQQQAGARKKELL---ERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLL 859
E L K R Q +K L+ ++ A + ++ P A EE+ L P
Sbjct: 9630 EPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEE-- 9687
Query: 860 PFPGAQVRQNVKNRLLVKNQDVSI 883
P A+V + K +VK + VSI
Sbjct: 9688 --PPAKVTEFRKR--VVKEEKVSI 9707
Score = 45.1 bits (105), Expect = 4e-04
Identities = 98/447 (21%), Positives = 158/447 (35%), Gaps = 83/447 (18%)
Query: 529 RPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPP 588
+P P GP P T+ +P ++P P P + ++ P P +PP
Sbjct: 10435 KPKAPPKGPEISEKIIPPKKPPTK-VVPRKEPPAKVPEVP-KKIVVEEKVRVPEEPRVPP 10492
Query: 589 PHQPQPQQPQQQPPPQHQP--PHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP- 645
P+ P++ P + P P + P PPP+ P+ P + P+ + VP
Sbjct: 10493 TKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPK---VPEAPKEVVPEKK---------VPV 10540
Query: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRN 705
PPP P P P V P+A+ + P+ + P + P
Sbjct: 10541 PPPKKPEVPPTKVPEV----PKAAVPEKKVPE-------------AIPPKPESPPP---- 10579
Query: 706 SNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPAS 765
E+P AP V+ + +V P+ P V E KV
Sbjct: 10580 ----EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVP---------EKKV---- 10622
Query: 766 PVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLE 825
PV PK+ T+ P+ + ++ + E K++ E I + E + E+ E
Sbjct: 10623 PVPPPKKPEVPPTKVPE------VPKVAVPE-KKVPEAIPPKPE--------SPPPEVFE 10667
Query: 826 RLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLL---VKNQDVS 882
++ L PP +E + +P P P P + V + VK +V
Sbjct: 10668 E--PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVP 10725
Query: 883 ISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTR--TVPQSQTQPLHKV--LPIKPADV 938
V K V + + K + + VP+ P KV +P KP
Sbjct: 10726 KEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLE 10785
Query: 939 EEPAVPQTPRVAS----IQGRPQDTKP 961
E+PAVP R S + P++ P
Sbjct: 10786 EKPAVPVPERAESPPPEVYEEPEEIAP 10812
Score = 44.3 bits (103), Expect = 7e-04
Identities = 84/431 (19%), Positives = 156/431 (36%), Gaps = 68/431 (15%)
Query: 563 PGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQP- 621
P P P LP P P+ P P + +P P+ P+ P + P P+ +P
Sbjct: 9284 PPPKVPELPEKPAPEEVAPV----PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPA 9339
Query: 622 -PPQHP--PQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFR-PHVQTAQPQASSSRMQCPQ 677
PP+ P P+ P + +P P P + P VQ + + ++
Sbjct: 9340 APPKVPEVPKKPVPEE--------KIPVPVAKKKEAPPAKVPEVQ--KGVVTEEKITIVT 9389
Query: 678 RQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPI 737
++ + K+ + + + PR E+P P V + A P+
Sbjct: 9390 QREESPPPAVPEIPKKKVPEERKPVPRKE--EEVP-PPPKVPALPKKPVPEEKVAVPVPV 9446
Query: 738 VSASPPSRAVAGSRS--------SQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRL 789
+PP RA ++ ++ K V V + + A+ E + +E+E +
Sbjct: 9447 AKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSI 9506
Query: 790 YRLKIEEQKRLREEILKQKELRRQ--------------QQAGARKKELLERLAQQQQQLY 835
+ EE++ E + + E+ + ++ A E+ ER Q+++ +
Sbjct: 9507 SVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTER--QEKKIVL 9564
Query: 836 APPPPAEQEEQALSPSPTNGNPLLP-------------FPGAQVRQNVKNRLLVKNQDVS 882
P PA+ EE + P ++P P +V + K + K
Sbjct: 9565 KPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPK 9624
Query: 883 ISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQ-------PLHKVLPIKP 935
+ ++ V + +MQ Q+ K L + + P+++ P KVL +KP
Sbjct: 9625 VIKMEEPLPAKV-TERHMQIT-QEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKP 9682
Query: 936 ADVEEPAVPQT 946
EEP T
Sbjct: 9683 KREEEPPAKVT 9693
Score = 40.0 bits (92), Expect = 0.013
Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 39/190 (20%)
Query: 294 ESTERGRMKDHRPALLP-----TQPPVVPQAPPPPPPPPQQQPI---RSLFQPQPLQPLL 345
+S R R ++ P + P + P VP+ PPP P + P R P+P + +
Sbjct: 10950 KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK--V 11007
Query: 346 PVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPL-L 404
P P P P P+ E + PPPV P+ TP+ P+ +
Sbjct: 11008 PEIKPAIPLPAPEPKPKPEAEV--KTIKPPPVEPEP---------------TPIAAPVTV 11050
Query: 405 PVPSQPRPAVGPQRFPGPPE-----FPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRD 459
PV + A P+ P+ P+ TP P+ + R L+ PP D
Sbjct: 11051 PVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPI-----EAERRKLRPGSGGEKPP-DEA 11104
Query: 460 PFFLGVSGEP 469
PF + P
Sbjct: 11105 PFTYQLKAVP 11114
Score = 32.0 bits (71), Expect = 3.5
Identities = 30/130 (23%), Positives = 60/130 (46%), Gaps = 16/130 (12%)
Query: 753 SQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLY---RLKIEEQKRLREEILKQKE 809
++ + E ++P + Q E K+E +F ++E++R + ++ E + EE K
Sbjct: 32198 AEREDEELLRPVT-TTQHLSEYKSELDFMSKEEKSRKKSRRQREVTEITEIEEEYEISKH 32256
Query: 810 LRRQQQAGA-----RKKEL----LERLAQQQQQLYAPPPPAEQEE---QALSPSPTNGNP 857
+R+ + A R++ L +E + + + + P PAE+ E + SP+P P
Sbjct: 32257 AQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRP 32316
Query: 858 LLPFPGAQVR 867
P P + R
Sbjct: 32317 RSPSPVSSER 32326
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 91.3 bits (225), Expect = 5e-18
Identities = 125/481 (25%), Positives = 159/481 (33%), Gaps = 87/481 (18%)
Query: 311 TQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRM 370
+Q P P PPP PP Q P P QP + PH P G H P + T RM
Sbjct: 152 SQGPARPYHPPPLFPPSPQPP-----DSTPRQPEASFE-PHPSVTPTGYHAPMEPPTSRM 205
Query: 371 MMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTP 430
PP P P+ + P G V L P P+ GP QH P
Sbjct: 206 FQAPPGAPPPHPQ---LYPGGTGGV-------LSGPPMGPKGGGAASSVGGPNGGKQHPP 255
Query: 431 GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSP--PPPPPP 488
P S S APP P +G P P +P PPPP
Sbjct: 256 PTTPISVSS------SGASGAPPTKPPTTP--VGGGNLPSAPPPANFPHVTPNLPPPPAL 307
Query: 489 PTLLNSSHPVP--TQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQP 546
L N+S P PLP P P QG + P P + P P S P
Sbjct: 308 RPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP--GPEKGPTLAPSP-----HSLP 360
Query: 547 GSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPP--- 603
++++ P P R P+ + + + P P Q P P PPP
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP--FPASQALPSYPHSFPPPTSL 418
Query: 604 --QHQPP-------------HQPPHQPPP-------QHQPPPQHPPQ-------HPPQHQ 634
+QPP Q P PPP + P PP HPP
Sbjct: 419 SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVST 478
Query: 635 HHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRP 694
HHHHH Q Q + H + P + P G H+ +S
Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA--FPHPLEGGSSHHAHPYAMS--- 533
Query: 695 MQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQ 754
P +LR P P+H + S+ S + + P VS+S S S +SQ
Sbjct: 534 --------PSLGSLRPYPPGPAH-LPPPHSQVSYSQAGPNGPPVSSSSNS----SSSTSQ 580
Query: 755 G 755
G
Sbjct: 581 G 581
Score = 84.3 bits (207), Expect = 6e-16
Identities = 147/615 (23%), Positives = 209/615 (33%), Gaps = 125/615 (20%)
Query: 310 PTQPPV-------VPQAPPPP---------PPPPQQQPIRSLFQPQPLQPLLPVQHPHHP 353
PT+PP +P APPP PPPP +P+ + P P+ H P
Sbjct: 272 PTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-HLP 330
Query: 354 SPP---QGMH-MPPQLET-PRMMMTP---PPVTPQQPKNIHINPHFKGTVVTPVQVPLLP 405
SP QGM +PP E P + +P PP + P P + +
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA-----PPMRFPYSSSSSSSAAA 385
Query: 406 VPSQPRPAVGPQRFPGP---PEFPQHTPGPVPNSFS-QPPR-----LPLQDQWRAPPPPQ 456
S + FP P +P P P S S QPP+ LP Q W PPP
Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPP 445
Query: 457 DRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQ 516
P + L P P PP +++HP + Q QQ
Sbjct: 446 ------------PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 517 GQQPVFPRERPVRPALQPPGPV------GILHFSQPGSATTRPFIPPRQPFLPGPGQPFL 570
QQ ++ PPG G H + P + + P + +P+ PGP
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS--PSLGSLRPYPPGPAH-LP 550
Query: 571 PTHTQPNLQ--GPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQ---- 624
P H+Q + GP PP+ Q P H P Q P P P P
Sbjct: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610
Query: 625 ---------------------HPPQHPPQHQHHHHHH-HLSVPPPPLMPMSQPQFR---- 658
PP PP + + + PP P S P FR
Sbjct: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
Query: 659 PHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHV 718
P + P A + S V P+ P+ +L P AP+
Sbjct: 671 PGYRGTSPPAGPGTFK----------PGSPTVGPGPLPPAGPSGL--PSLPPPPAAPASG 718
Query: 719 IEMSSSRCSA-------TPSAQVKPIVSASPPSRAV-AGSRSSQGKTEVK--------VK 762
+S+++ TP + V P S SPP + V S +SQ K
Sbjct: 719 PPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCA 778
Query: 763 PASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKE 822
+ P E +K + D E+ R E ++R REE +++E R+++ K+
Sbjct: 779 RSDLYFVPLEGSKLAKKRADLVEKVRR-----EAEQRAREEKEREREREREKEREREKER 833
Query: 823 LLERLAQQQQQLYAP 837
LER + Q+ AP
Sbjct: 834 ELERSVKLAQEGRAP 848
Score = 65.9 bits (159), Expect = 2e-10
Identities = 155/673 (23%), Positives = 204/673 (30%), Gaps = 139/673 (20%)
Query: 428 HTPGPVPNS------FSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRS 481
++PG V N SQ P P PP PQ D PR P F S
Sbjct: 136 YSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPD-------STPRQPEASFEPHPS 188
Query: 482 PPP-----PPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPAL---- 532
P P PPT P P P PG P+ P+ ++
Sbjct: 189 VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 533 ---QPPGPVGILHFSQPGSATTRPFIPPRQPF----LPGPGQPFLPTHTQPNLQGPLHPP 585
Q P P + S G++ P PP P LP P H PNL P P
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP--PA 306
Query: 586 LPPPHQPQPQQPQ--QQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLS 643
L P + P QP P H P Q P P+ P P S
Sbjct: 307 LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH--------S 358
Query: 644 VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAP 703
+PP + P P+ ++ A++S +++S + S P Q P+ P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSS---------SSSSSSASPFPASQALPSYP 409
Query: 704 RNSNLRELPIAPSHVIEMSSSRCSAT-PSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVK 762
+ P + +S+ T PS + + S PP G +
Sbjct: 410 HS-------FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPF 462
Query: 763 PASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKE 822
P S AQ T ++ + Q++ ++QQQ
Sbjct: 463 PPSTGAQSTAHPPVSTHHHHHQQQQQ------------------QQQQQQQQQ------- 497
Query: 823 LLERLAQQQQQLY---APPPPA------------EQEEQALSPSPTNGNPLLPFPGAQVR 867
QQQQQ + PPPP A+SPS + P P P
Sbjct: 498 ------QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA---- 547
Query: 868 QNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPL 927
L + VS S P SS + Q H ++ PQ P
Sbjct: 548 -----HLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQG-PQGAPYPF 601
Query: 928 HKVLPIKPADVEEPAV-------PQTPRVASIQGRPQDTK----PGVKRTVTHRTNSGGG 976
V + + V P + AS G P K PG +T T G
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT-----PPG 656
Query: 977 DGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPH 1036
P R G G S P G P P VGP P L G P
Sbjct: 657 YKPGSPPSFRTGTPPGYRGTSP----PAGPGTFKPGSPTVGPGP-----LPPAGPSGLPS 707
Query: 1037 LPAGPHAHSPVPP 1049
LP P A + PP
Sbjct: 708 LPPPPAAPASGPP 720
Score = 35.4 bits (80), Expect = 0.32
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 6/84 (7%)
Query: 308 LLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLET 367
L P P +P PPPP P P+ + Q +P + P P PP PP
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ--EPAEEYETPESPVPPARSPSPP---- 750
Query: 368 PRMMMTPPPVTPQQPKNIHINPHF 391
P+++ P + N H++ F
Sbjct: 751 PKVVDVPSHASQSARFNKHLDRGF 774
Score = 31.2 bits (69), Expect = 6.0
Identities = 55/230 (23%), Positives = 72/230 (31%), Gaps = 43/230 (18%)
Query: 933 IKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSG 992
+ P P P T R+ Q P P H GG G +S K
Sbjct: 189 VTPTGYHAPMEPPTSRM--FQAPPGAPPP-------HPQLYPGGTGGVLSGPPMGPK--- 236
Query: 993 GGGESDGFFHPEGQPQRLPQPPEV--------GPQPARKVTLTRGGLQQP---------- 1034
GGG + P G Q P + G P + T GG P
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296
Query: 1035 --PHLPAGPHAH-----SPVPPGI--KSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNK 1085
P+LP P S PPG+ + + G P+ A+ G G GP L P+
Sbjct: 297 VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP 356
Query: 1086 QNL----RVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPIQSLQMLP 1131
+L P S SS+ + S S P + Q LP
Sbjct: 357 HSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP 406
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 91.3 bits (225), Expect = 5e-18
Identities = 125/481 (25%), Positives = 159/481 (33%), Gaps = 87/481 (18%)
Query: 311 TQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRM 370
+Q P P PPP PP Q P P QP + PH P G H P + T RM
Sbjct: 152 SQGPARPYHPPPLFPPSPQPP-----DSTPRQPEASFE-PHPSVTPTGYHAPMEPPTSRM 205
Query: 371 MMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTP 430
PP P P+ + P G V L P P+ GP QH P
Sbjct: 206 FQAPPGAPPPHPQ---LYPGGTGGV-------LSGPPMGPKGGGAASSVGGPNGGKQHPP 255
Query: 431 GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSP--PPPPPP 488
P S S APP P +G P P +P PPPP
Sbjct: 256 PTTPISVSS------SGASGAPPTKPPTTP--VGGGNLPSAPPPANFPHVTPNLPPPPAL 307
Query: 489 PTLLNSSHPVP--TQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQP 546
L N+S P PLP P P QG + P P + P P S P
Sbjct: 308 RPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP--GPEKGPTLAPSP-----HSLP 360
Query: 547 GSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPP--- 603
++++ P P R P+ + + + P P Q P P PPP
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP--FPASQALPSYPHSFPPPTSL 418
Query: 604 --QHQPP-------------HQPPHQPPP-------QHQPPPQHPPQ-------HPPQHQ 634
+QPP Q P PPP + P PP HPP
Sbjct: 419 SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVST 478
Query: 635 HHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRP 694
HHHHH Q Q + H + P + P G H+ +S
Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA--FPHPLEGGSSHHAHPYAMS--- 533
Query: 695 MQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQ 754
P +LR P P+H + S+ S + + P VS+S S S +SQ
Sbjct: 534 --------PSLGSLRPYPPGPAH-LPPPHSQVSYSQAGPNGPPVSSSSNS----SSSTSQ 580
Query: 755 G 755
G
Sbjct: 581 G 581
Score = 84.3 bits (207), Expect = 6e-16
Identities = 147/615 (23%), Positives = 209/615 (33%), Gaps = 125/615 (20%)
Query: 310 PTQPPV-------VPQAPPPP---------PPPPQQQPIRSLFQPQPLQPLLPVQHPHHP 353
PT+PP +P APPP PPPP +P+ + P P+ H P
Sbjct: 272 PTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-HLP 330
Query: 354 SPP---QGMH-MPPQLET-PRMMMTP---PPVTPQQPKNIHINPHFKGTVVTPVQVPLLP 405
SP QGM +PP E P + +P PP + P P + +
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA-----PPMRFPYSSSSSSSAAA 385
Query: 406 VPSQPRPAVGPQRFPGP---PEFPQHTPGPVPNSFS-QPPR-----LPLQDQWRAPPPPQ 456
S + FP P +P P P S S QPP+ LP Q W PPP
Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPP 445
Query: 457 DRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQ 516
P + L P P PP +++HP + Q QQ
Sbjct: 446 ------------PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 517 GQQPVFPRERPVRPALQPPGPV------GILHFSQPGSATTRPFIPPRQPFLPGPGQPFL 570
QQ ++ PPG G H + P + + P + +P+ PGP
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS--PSLGSLRPYPPGPAH-LP 550
Query: 571 PTHTQPNLQ--GPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQ---- 624
P H+Q + GP PP+ Q P H P Q P P P P
Sbjct: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610
Query: 625 ---------------------HPPQHPPQHQHHHHHH-HLSVPPPPLMPMSQPQFR---- 658
PP PP + + + PP P S P FR
Sbjct: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
Query: 659 PHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHV 718
P + P A + S V P+ P+ +L P AP+
Sbjct: 671 PGYRGTSPPAGPGTFK----------PGSPTVGPGPLPPAGPSGL--PSLPPPPAAPASG 718
Query: 719 IEMSSSRCSA-------TPSAQVKPIVSASPPSRAV-AGSRSSQGKTEVK--------VK 762
+S+++ TP + V P S SPP + V S +SQ K
Sbjct: 719 PPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCA 778
Query: 763 PASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKE 822
+ P E +K + D E+ R E ++R REE +++E R+++ K+
Sbjct: 779 RSDLYFVPLEGSKLAKKRADLVEKVRR-----EAEQRAREEKEREREREREKEREREKER 833
Query: 823 LLERLAQQQQQLYAP 837
LER + Q+ AP
Sbjct: 834 ELERSVKLAQEGRAP 848
Score = 65.9 bits (159), Expect = 2e-10
Identities = 155/673 (23%), Positives = 204/673 (30%), Gaps = 139/673 (20%)
Query: 428 HTPGPVPNS------FSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRS 481
++PG V N SQ P P PP PQ D PR P F S
Sbjct: 136 YSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPD-------STPRQPEASFEPHPS 188
Query: 482 PPP-----PPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPAL---- 532
P P PPT P P P PG P+ P+ ++
Sbjct: 189 VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 533 ---QPPGPVGILHFSQPGSATTRPFIPPRQPF----LPGPGQPFLPTHTQPNLQGPLHPP 585
Q P P + S G++ P PP P LP P H PNL P P
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP--PA 306
Query: 586 LPPPHQPQPQQPQ--QQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLS 643
L P + P QP P H P Q P P+ P P S
Sbjct: 307 LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH--------S 358
Query: 644 VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAP 703
+PP + P P+ ++ A++S +++S + S P Q P+ P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSS---------SSSSSSASPFPASQALPSYP 409
Query: 704 RNSNLRELPIAPSHVIEMSSSRCSAT-PSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVK 762
+ P + +S+ T PS + + S PP G +
Sbjct: 410 HS-------FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPF 462
Query: 763 PASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKE 822
P S AQ T ++ + Q++ ++QQQ
Sbjct: 463 PPSTGAQSTAHPPVSTHHHHHQQQQQ------------------QQQQQQQQQ------- 497
Query: 823 LLERLAQQQQQLY---APPPPA------------EQEEQALSPSPTNGNPLLPFPGAQVR 867
QQQQQ + PPPP A+SPS + P P P
Sbjct: 498 ------QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA---- 547
Query: 868 QNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPL 927
L + VS S P SS + Q H ++ PQ P
Sbjct: 548 -----HLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQG-PQGAPYPF 601
Query: 928 HKVLPIKPADVEEPAV-------PQTPRVASIQGRPQDTK----PGVKRTVTHRTNSGGG 976
V + + V P + AS G P K PG +T T G
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT-----PPG 656
Query: 977 DGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPH 1036
P R G G S P G P P VGP P L G P
Sbjct: 657 YKPGSPPSFRTGTPPGYRGTSP----PAGPGTFKPGSPTVGPGP-----LPPAGPSGLPS 707
Query: 1037 LPAGPHAHSPVPP 1049
LP P A + PP
Sbjct: 708 LPPPPAAPASGPP 720
Score = 35.4 bits (80), Expect = 0.32
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 6/84 (7%)
Query: 308 LLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLET 367
L P P +P PPPP P P+ + Q +P + P P PP PP
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ--EPAEEYETPESPVPPARSPSPP---- 750
Query: 368 PRMMMTPPPVTPQQPKNIHINPHF 391
P+++ P + N H++ F
Sbjct: 751 PKVVDVPSHASQSARFNKHLDRGF 774
Score = 31.2 bits (69), Expect = 6.0
Identities = 55/230 (23%), Positives = 72/230 (31%), Gaps = 43/230 (18%)
Query: 933 IKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSG 992
+ P P P T R+ Q P P H GG G +S K
Sbjct: 189 VTPTGYHAPMEPPTSRM--FQAPPGAPPP-------HPQLYPGGTGGVLSGPPMGPK--- 236
Query: 993 GGGESDGFFHPEGQPQRLPQPPEV--------GPQPARKVTLTRGGLQQP---------- 1034
GGG + P G Q P + G P + T GG P
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296
Query: 1035 --PHLPAGPHAH-----SPVPPGI--KSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNK 1085
P+LP P S PPG+ + + G P+ A+ G G GP L P+
Sbjct: 297 VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP 356
Query: 1086 QNL----RVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPIQSLQMLP 1131
+L P S SS+ + S S P + Q LP
Sbjct: 357 HSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP 406
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,921,017
Number of Sequences: 37866
Number of extensions: 5312759
Number of successful extensions: 113306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1034
Number of HSP's successfully gapped in prelim test: 2086
Number of HSP's that attempted gapping in prelim test: 31772
Number of HSP's gapped (non-prelim): 36397
length of query: 1170
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1057
effective length of database: 13,968,660
effective search space: 14764873620
effective search space used: 14764873620
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.