Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 150378503
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
(547 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 1086 0.0
gi|54607116 leiomodin 3 (fetal) [Homo sapiens] 336 3e-92
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens] 290 3e-78
gi|7657647 neuronal tropomodulin isoform a [Homo sapiens] 247 2e-65
gi|4507553 tropomodulin 1 [Homo sapiens] 237 2e-62
gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens] 231 1e-60
gi|156415984 tropomodulin 4 (muscle) [Homo sapiens] 215 7e-56
gi|218931148 neuronal tropomodulin isoform b [Homo sapiens] 197 3e-50
gi|52485606 formin-like 2 [Homo sapiens] 71 2e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is... 70 5e-12
gi|56549694 enabled homolog isoform a [Homo sapiens] 69 1e-11
gi|39930375 enabled homolog isoform b [Homo sapiens] 69 1e-11
gi|148613878 acrosin precursor [Homo sapiens] 68 2e-11
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 67 3e-11
gi|150170670 piccolo isoform 2 [Homo sapiens] 67 5e-11
gi|150378539 piccolo isoform 1 [Homo sapiens] 67 5e-11
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 65 1e-10
gi|149944526 additional sex combs like 3 [Homo sapiens] 65 1e-10
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 65 2e-10
gi|158534059 formin binding protein 4 [Homo sapiens] 65 2e-10
gi|33356148 formin-like 1 [Homo sapiens] 64 3e-10
gi|157168329 formin 1 [Homo sapiens] 64 4e-10
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 62 1e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 62 2e-09
gi|60460889 Myb protein P42POP [Homo sapiens] 62 2e-09
gi|195947369 junction-mediating and regulatory protein [Homo sap... 61 3e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 60 4e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 60 4e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 60 7e-09
gi|153792074 proline rich 12 [Homo sapiens] 60 7e-09
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 1086 bits (2808), Expect = 0.0
Identities = 547/547 (100%), Positives = 547/547 (100%)
Query: 1 MSTFGYRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTP 60
MSTFGYRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTP
Sbjct: 1 MSTFGYRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTP 60
Query: 61 TGTFSREALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEE 120
TGTFSREALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEE
Sbjct: 61 TGTFSREALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEE 120
Query: 121 EEEESQEEEEEEDSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINLTNGSN 180
EEEESQEEEEEEDSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINLTNGSN
Sbjct: 121 EEEESQEEEEEEDSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINLTNGSN 180
Query: 181 GRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDNT 240
GRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDNT
Sbjct: 181 GRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDNT 240
Query: 241 VVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTE 300
VVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTE
Sbjct: 241 VVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTE 300
Query: 301 LRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRL 360
LRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRL
Sbjct: 301 LRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRL 360
Query: 361 QEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVAT 420
QEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVAT
Sbjct: 361 QEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVAT 420
Query: 421 PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKK 480
PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKK
Sbjct: 421 PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKK 480
Query: 481 KGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRV 540
KGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRV
Sbjct: 481 KGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRV 540
Query: 541 EVPEALR 547
EVPEALR
Sbjct: 541 EVPEALR 547
>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
Length = 560
Score = 336 bits (862), Expect = 3e-92
Identities = 218/583 (37%), Positives = 314/583 (53%), Gaps = 89/583 (15%)
Query: 14 ESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGTFSREALM--A 71
E I+EDE+LA+LSAEELKEL+ E+E + PD +LPVG+ QK T+K PTG F+ ++L+
Sbjct: 16 EEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHKSLVDYM 75
Query: 72 YWEKESQKLLEKERLGECGKVAEDK--EESEE------------------ELIFTESNSE 111
YWEK S+++LE+ER+ +E+K EE EE E++ + S+
Sbjct: 76 YWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESK 135
Query: 112 VSEEVYTEEEEEESQEEEEEEDSDEE--ERTIETAKGINGTVNYDSVNSDNS----KPKI 165
S + +EE+E +E+++++D E+ E + ET + G N +N+ K
Sbjct: 136 GSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKA 195
Query: 166 FKSQIENINLTNGSNGRNTESP------------AAIHPCGNPTVIEDALDKIKSNDPDT 213
FK Q + S + ++ + P GN T ++ +L +++ NDPD
Sbjct: 196 FKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDM 255
Query: 214 TEVNLNNIENITTQTLTRFAEALKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNV 273
E+NLNNIENI + L F A+K N +KTFSLAN AD++ A A+A ML+ N IT +
Sbjct: 256 KELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITTL 315
Query: 274 NVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGY 333
N+ESNFITGKGI+AIMR LQ N LTELRFHNQRH++G EMEI +LLK N TLL++GY
Sbjct: 316 NIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGY 375
Query: 334 HFELPGPRMSMTSILTRNMDKQRQKRLQEQKQQE---------GYDGGPNLRTKVWQRGT 384
HFELPGPRM +T++LTRN DKQRQKR +EQKQQ+ + G L +W+
Sbjct: 376 HFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWEL-- 433
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444
PK ++Q PPPP PP P P SQR P
Sbjct: 434 -------------LGGPKPDSRMQ--------EFFQPPPPRPPNPQNVPFSQRSEMMKKP 472
Query: 445 PPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSI-LKEIKNSLRSV 503
P K + V+K L+ Q+K + + ++ P LK++ +L+ V
Sbjct: 473 SQAP---KYRTDPDSFRVVK--------LKRIQRKSRMPEAREPPEKTNLKDVIKTLKPV 521
Query: 504 QEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRVEVPEAL 546
+ P + + + L+ IR SS+ LK V++P+ L
Sbjct: 522 PRNR-----PPPLVEITPRDQLLNDIRHSSVAYLKPVQLPKEL 559
>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
Length = 600
Score = 290 bits (741), Expect = 3e-78
Identities = 206/560 (36%), Positives = 284/560 (50%), Gaps = 105/560 (18%)
Query: 7 RRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGTFSR 66
R GL K S D DE S E+ KE E+ + I+ R ++ +K G R
Sbjct: 127 RGGLKKSFSRDRDEA-GGKSGEKPKE-EKIIRGIDKGR-------VRAAVDKKEAGKDGR 177
Query: 67 EALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEE---VYTEEEEE 123
A K+ ++ +R + + K E +E+ E + +V E T +E E
Sbjct: 178 GEERAVATKKEEEKKGSDRNTGLSRDKDKKREEMKEVAKKEDDEKVKGERRNTDTRKEGE 237
Query: 124 ESQEEEEEEDSDEEERTIETAKGINGTVN-----------YDSVNSDNSKPKIFKSQIEN 172
+ + D +E+ ++ G T ++ D+SK K + Q
Sbjct: 238 KMKRAGGNTDMKKEDEKVKRGTGNTDTKKDDEKVKKNEPLHEKEAKDDSKTKTPEKQ--- 294
Query: 173 INLTNGSNGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRF 232
T + +E PA + P++ ++ L+++K+NDP+ TEVN+NN + IT + L RF
Sbjct: 295 ---TPSGPTKPSEGPAKVEEEAAPSIFDEPLERVKNNDPEMTEVNVNNSDCITNEILVRF 351
Query: 233 AEALKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRAL 292
EAL+ NTVVK F+LANT ADD A AIA MLK N+ IT++N++SN ITGKGILAI RAL
Sbjct: 352 TEALEFNTVVKLFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHITGKGILAIFRAL 411
Query: 293 QHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNM 352
N LTELRFHNQRHI G + EMEI KLLKENTTLL+LGYHFEL GPRM++T++L+RNM
Sbjct: 412 LQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTNLLSRNM 471
Query: 353 DKQRQKRLQEQKQQEGYDGGPNLRTKVWQ-----RGTPSSSPYVSPRHSPWSSPKLPKKV 407
DKQRQKRLQEQ+Q + G +V + +G+P SP SP+ SP +SPK
Sbjct: 472 DKQRQKRLQEQRQAQEAKGEKKDLLEVPKAGAVAKGSPKPSPQPSPKPSPKNSPK----- 526
Query: 408 QTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQE 467
+ +P A PPPPPP PP LI N+
Sbjct: 527 -----KGGAPAAPPPPPPPLAPP-----------------------LIMENL-------- 550
Query: 468 SAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLME 527
+ +L ++K G KV QEK D L+
Sbjct: 551 --KNSLSPATQRKMGDKV---------------LPAQEKNSRD-------------QLLA 580
Query: 528 AIRGSSIKQLKRVEVPEALR 547
AIR S++KQLK+VEVP+ L+
Sbjct: 581 AIRSSNLKQLKKVEVPKLLQ 600
>gi|7657647 neuronal tropomodulin isoform a [Homo sapiens]
Length = 351
Score = 247 bits (630), Expect = 2e-65
Identities = 149/370 (40%), Positives = 219/370 (59%), Gaps = 33/370 (8%)
Query: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRN-LPVGLRQKSLTEKTPTGTF 64
+++ L KY++IDEDELL LS EELK+LE L+D++P+ LP G RQK T+K TG F
Sbjct: 5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPF 64
Query: 65 SREALMAYWEKESQKLLEKERL----GEC-GKVAEDKEESEEELIFTESNSEVSEEVYTE 119
RE L+ Y EKE+ + ++E GE G+V KE+ E T
Sbjct: 65 DREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIE----------------TR 108
Query: 120 EEEEESQEEEEEED----SDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINL 175
+EE+ + + E EE SD E + G++ +N + + + K K + N+
Sbjct: 109 KEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVK 168
Query: 176 TNGSNGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEA 235
E P NPT +E +L ++K+NDP EVNLNNI+NI TL FA+A
Sbjct: 169 GEKVKPVFEEPP-------NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKA 221
Query: 236 LKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHN 295
L+ NT VK FSLA T ++D A+A A+MLKVN+ +T++N+ESNFITG GILA++ AL+ N
Sbjct: 222 LETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKEN 281
Query: 296 TVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQ 355
LTE++ NQR +G+ VEMEI ++L+EN+ +L+ GY F GPR + + +T+N D
Sbjct: 282 DTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLV 341
Query: 356 RQKRLQEQKQ 365
R+KR++ ++
Sbjct: 342 RKKRVEADRR 351
>gi|4507553 tropomodulin 1 [Homo sapiens]
Length = 359
Score = 237 bits (604), Expect = 2e-62
Identities = 147/363 (40%), Positives = 212/363 (58%), Gaps = 25/363 (6%)
Query: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNL-PVGLRQKSLTEKTPTGTF 64
YRR L KY +DEDE+L +L+ EEL+ LE EL++++PD L P GLRQK T K PTG F
Sbjct: 3 YRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPF 62
Query: 65 SREALMAYWEKESQKLLEKERL----GEC-GKVAEDKEESEEELIFTESNSEVSEEVYTE 119
RE L+ + EK++++ ++E L GE GKV K++ + ++ E V E
Sbjct: 63 KREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVL---------ESVTLE 113
Query: 120 EEEEESQEEEEEEDSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINLTNGS 179
E EE+ SD E I G++ ++ S I E +N S
Sbjct: 114 PELEEALANA----SDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNK--EGLN----S 163
Query: 180 NGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDN 239
+ T+ N T +E+ L++IK+NDP EVNLNNI NI TL +AEALK+N
Sbjct: 164 VIKPTQYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKEN 223
Query: 240 TVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLT 299
+ VK FS+ T ++D A A+AEMLK N+ + +NVESNFI+G GIL ++ AL +NT L
Sbjct: 224 SYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLV 283
Query: 300 ELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKR 359
E++ NQ +G++VEMEIV +L++N TLL+ GYHF GPR+ ++ + N D R++R
Sbjct: 284 EMKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRR 343
Query: 360 LQE 362
L +
Sbjct: 344 LAD 346
>gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]
Length = 352
Score = 231 bits (590), Expect = 1e-60
Identities = 149/365 (40%), Positives = 209/365 (57%), Gaps = 22/365 (6%)
Query: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNL-PVGLRQKSLTEKTPTGTF 64
+R+ L KY+ +DEDELL +LS ELK+LE L+D++P+ L P G RQK+ T K+ TG F
Sbjct: 5 FRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPF 64
Query: 65 SREALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEEEEEE 124
RE L++Y EKE+ L K+R E K + IF V + +TEE+
Sbjct: 65 DREHLLSYLEKEA--LEHKDREDYVPYTGEKKGK-----IFIPKQKPV--QTFTEEKVSL 115
Query: 125 SQEEEEE--EDSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINLTNGSNGR 182
E EE SD E + G++ + N+K ++ + SN
Sbjct: 116 DPELEEALTSASDTELCDLAAILGMHNLIT-------NTKFCNIMGSSNGVDQEHFSNVV 168
Query: 183 NTES--PAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDNT 240
E P P NPT +E++L + K ND EVNLNNI+NI TL FA+AL+ NT
Sbjct: 169 KGEKILPVFDEP-PNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNT 227
Query: 241 VVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTE 300
VK FSLA T ++D A A AEMLKVN+ + ++NVESNFITG GILA++ AL+ N L E
Sbjct: 228 HVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAE 287
Query: 301 LRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRL 360
L+ NQR +G+ VE+E+ K+L+ENT +L+ GY F GPR + +T+N D R++R+
Sbjct: 288 LKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRV 347
Query: 361 QEQKQ 365
+ Q
Sbjct: 348 EGDHQ 352
>gi|156415984 tropomodulin 4 (muscle) [Homo sapiens]
Length = 345
Score = 215 bits (548), Expect = 7e-56
Identities = 125/355 (35%), Positives = 205/355 (57%), Gaps = 16/355 (4%)
Query: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNL-PVGLRQKSLTEKTPTGTF 64
Y++ L KY IDEDE+L +LS EEL++L+ EL++++P+ L P GLRQ+ T+K+PTG
Sbjct: 4 YQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPL 63
Query: 65 SREALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEEEEEE 124
REAL+ Y E+++ ++ E++ L V E+ + I + E++ E E EE
Sbjct: 64 DREALLQYLEQQALEVKERDDL-----VPFTGEKKGKPYIQPKREIPAEEQITLEPELEE 118
Query: 125 SQEEEEEEDSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINLTNGSNGRNT 184
+ + + + ++ ++ YD++ S +I N + +
Sbjct: 119 ALAHATDAEMCDIAAILDMYTLMSNKQYYDALCS---------GEICNTEGISSVVQPDK 169
Query: 185 ESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDNTVVKT 244
P P NPT IE+ L +++SND + EVNLNNI++I L+ EA+K NT V++
Sbjct: 170 YKPVPDEP-PNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRS 228
Query: 245 FSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTELRFH 304
FSL T + D A A+A+ML+ N + ++N+ESNFI+ G++A+++A++ N LTELR
Sbjct: 229 FSLVATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVD 288
Query: 305 NQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKR 359
NQR G VEME+ +L++ +++R GYHF GPR +TRN + +RQ++
Sbjct: 289 NQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQK 343
>gi|218931148 neuronal tropomodulin isoform b [Homo sapiens]
Length = 315
Score = 197 bits (500), Expect = 3e-50
Identities = 128/370 (34%), Positives = 195/370 (52%), Gaps = 69/370 (18%)
Query: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPD-RNLPVGLRQKSLTEKTPTGTF 64
+++ L KY++IDEDELL LS EELK+LE L+D++P+ LP G RQK T+K TG F
Sbjct: 5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPF 64
Query: 65 SREALMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFT-ESNSEV----SEEVYTE 119
RE L+ Y EKE A ++++ E+ + FT E V + + T
Sbjct: 65 DREHLLMYLEKE----------------ALEQKDREDFVPFTGEKKGRVFIPKEKPIETR 108
Query: 120 EEEEESQEEEEEE----DSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINL 175
+EE+ + + E EE SD E + G++ +N + + + K K + N+
Sbjct: 109 KEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVK 168
Query: 176 TNGSNGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEA 235
E P NPT +E +L ++K+NDP EVNLNNI+
Sbjct: 169 GEKVKPVFEEPP-------NPTNVEISLQQMKANDPSLQEVNLNNIK------------- 208
Query: 236 LKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHN 295
A A+MLKVN+ +T++N+ESNFITG GILA++ AL+ N
Sbjct: 209 -----------------------AFADMLKVNKTLTSLNIESNFITGTGILALVEALKEN 245
Query: 296 TVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQ 355
LTE++ NQR +G+ VEMEI ++L+EN+ +L+ GY F GPR + + +T+N D
Sbjct: 246 DTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLV 305
Query: 356 RQKRLQEQKQ 365
R+KR++ ++
Sbjct: 306 RKKRVEADRR 315
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 71.2 bits (173), Expect = 2e-12
Identities = 35/68 (51%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPP 442
G SS P P P LP T + PV P PPPPPPPPPPP PPPP
Sbjct: 519 GAASSGPLPPP------PPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPP-----PPPP 567
Query: 443 PPPPPPLP 450
PPPPPPLP
Sbjct: 568 PPPPPPLP 575
Score = 51.6 bits (122), Expect = 2e-06
Identities = 24/49 (48%), Positives = 26/49 (53%), Gaps = 12/49 (24%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQR------------LPPPPPPPPPPLP 450
P A+ P PPPPPP PPSS +PPPPPPPPPP P
Sbjct: 516 PTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPP 564
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 10/70 (14%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444
PSS + ++ P + P P P P PPPPP PPP P P+++ +P PP
Sbjct: 535 PSSDTPETVQNGPVTPPMPPPPPP-----PPPPPPPPPPPP-PPPLPGPAAETVPAPPLA 588
Query: 445 PP----PPLP 450
PP PPLP
Sbjct: 589 PPLPSAPPLP 598
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 70.1 bits (170), Expect = 5e-12
Identities = 39/105 (37%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 377 TKVWQRGTP---SSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPP 433
++ W+RGT SS + + P++S P Q P + PP PPPPPPPPP
Sbjct: 578 SEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP 637
Query: 434 SSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQK 478
PPPPPPPPPPLP + + A + + S LQN +
Sbjct: 638 P----PPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ 678
Score = 50.8 bits (120), Expect = 3e-06
Identities = 25/53 (47%), Positives = 30/53 (56%), Gaps = 6/53 (11%)
Query: 404 PKKVQTVRSRPL-SPVATPPPPPPPPPPPPPSSQRLPPPPP-----PPPPPLP 450
P+ V+++P P + P P P PPPPP SS PPPPP PPPPP P
Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944
Score = 49.3 bits (116), Expect = 9e-06
Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 9/62 (14%)
Query: 400 SPKLPKKVQTVRSRPLSPVATPPPPPPPPPP------PPPSSQRLPPPPPPPPP---PLP 450
+P+ P V+ S + P P PPPPP PPP +P PPPPPPP P P
Sbjct: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP 950
Query: 451 EK 452
+K
Sbjct: 951 DK 952
Score = 47.0 bits (110), Expect = 4e-05
Identities = 28/85 (32%), Positives = 33/85 (38%), Gaps = 35/85 (41%)
Query: 401 PKLPKKVQTVRSRP---LSPVATPPPPPPPPPPPPPSSQ----------------RLPPP 441
P P +Q+ +P + P PPPPPPPPPP P S PPP
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745
Query: 442 P----------------PPPPPPLP 450
P PPPPPP+P
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIP 770
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/79 (32%), Positives = 30/79 (37%), Gaps = 8/79 (10%)
Query: 382 RGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLP-- 439
+ P P P SP P P+ P SPV PPPPPPP P P P
Sbjct: 899 KAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK 958
Query: 440 ------PPPPPPPPPLPEK 452
P PPP P++
Sbjct: 959 KTSKTSSPGGKKPPPTPQR 977
Score = 44.7 bits (104), Expect = 2e-04
Identities = 40/133 (30%), Positives = 52/133 (39%), Gaps = 36/133 (27%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPP---PPP--PSSQRL- 438
P+S+ V+P + + P V + +P P + PP PP PP PPP P Q
Sbjct: 788 PTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFC 847
Query: 439 --PPP-----------------PPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKK 479
PPP PPPP PP E + + A V Q A +A
Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA------- 900
Query: 480 KKGKKVKKQPNSI 492
K K QP+SI
Sbjct: 901 ----KPKWQPSSI 909
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/92 (30%), Positives = 36/92 (39%), Gaps = 17/92 (18%)
Query: 391 VSPRHSPWSSPKLPKKVQTVRSRPLSP----VATPPPP-------------PPPPPPPPP 433
V P P P + ++ P +P + PPPP PP PPPPPP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 434 SSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQ 465
LPP PP P T+ +A V+ Q
Sbjct: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQ 800
Score = 43.1 bits (100), Expect = 6e-04
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 400 SPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKL 454
+P K V V ++ P TPP PP P P+S +PP PP PP P+P L
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASY-IPPSPPTPPVPVPPPTL 840
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 28/105 (26%)
Query: 384 TPSSSPYVSPRHSPWSSPK----LPKKVQTVRSRPLSPVATPPPPPPPPPP--------- 430
TP P + P + PK +P T P+ A PP P PP PP
Sbjct: 762 TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPA 821
Query: 431 ----PPPSSQRLPPPPP-----------PPPPPLPEKKLITRNIA 460
P P + +P PPP PPP PL + + IA
Sbjct: 822 SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866
Score = 38.1 bits (87), Expect = 0.021
Identities = 23/64 (35%), Positives = 25/64 (39%), Gaps = 6/64 (9%)
Query: 393 PRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPP------PPP 446
P +P + P K P SP A P P P S PPPPP PPP
Sbjct: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930
Query: 447 PPLP 450
PP P
Sbjct: 931 PPSP 934
Score = 36.2 bits (82), Expect = 0.079
Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 7/57 (12%)
Query: 404 PKKVQTVRSRPLSPVATPPPPPPPP-----PPPPPSSQRLPPPPPPPPPPLPEKKLI 455
P + S+PL PV P PP P PSS +P P P PPP PE L+
Sbjct: 872 PPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSS--IPVPSPDFPPPPPESSLV 926
Score = 36.2 bits (82), Expect = 0.079
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 13/99 (13%)
Query: 430 PPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGK-KVKKQ 488
P PPS PPPPP PLP + I V S + A+ N Q ++ K VKK
Sbjct: 1065 PSPPSDSDFPPPPPETELPLPPIE-----IPAVFSGNTSPKVAVVNPQPQQWSKMSVKKA 1119
Query: 489 PNSILKEIKNSLRSVQEKKMEDSSR-------PSTPQRS 520
P + +S R Q + E + P++P+ S
Sbjct: 1120 PPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSS 1158
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 68.6 bits (166), Expect = 1e-11
Identities = 49/162 (30%), Positives = 65/162 (40%), Gaps = 11/162 (6%)
Query: 373 PNLRTKVWQRGTPSSSPYV-SPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPP------P 425
P L+ TPS V P P P P Q + P P PPPP P
Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348
Query: 426 PPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKV 485
PPPPPPP +Q PPPPPPP PPLP +++E + A+ K +KV
Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGA----KLRKV 404
Query: 486 KKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLME 527
+ ++ N++ D+ R + P LME
Sbjct: 405 SRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLME 446
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/129 (30%), Positives = 53/129 (41%), Gaps = 29/129 (22%)
Query: 353 DKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPR----------HSPWSSPK 402
+++R +RL+ ++Q+ W+R SS S S P
Sbjct: 231 ERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG 290
Query: 403 L-----PKKVQTVRSRPLSPVATPPPPPPPPPP-------PPPSSQRLP-------PPPP 443
L P + + + L P+A PPPPP PP P PPP P PPPP
Sbjct: 291 LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP 350
Query: 444 PPPPPLPEK 452
PPPPPLP +
Sbjct: 351 PPPPPLPNQ 359
Score = 32.0 bits (71), Expect = 1.5
Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 4/133 (3%)
Query: 15 SIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLT-EKTPTGTFSREAL-MAY 72
S +E E+ E+ ++ E E E +E +R L ++ L E+ +E L
Sbjct: 136 SQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERER 195
Query: 73 WEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEEEEEESQEEEEEE 132
E+E Q+ LE++ E + E +E + E + + E + E +E E QE+ E E
Sbjct: 196 QERERQERLERQERLERQERLERQERLDRERQERQERERL-ERLERERQERERQEQLERE 254
Query: 133 DSD-EEERTIETA 144
+ E ER I +A
Sbjct: 255 QLEWERERRISSA 267
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 68.6 bits (166), Expect = 1e-11
Identities = 49/162 (30%), Positives = 65/162 (40%), Gaps = 11/162 (6%)
Query: 373 PNLRTKVWQRGTPSSSPYV-SPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPP------P 425
P L+ TPS V P P P P Q + P P PPPP P
Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348
Query: 426 PPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKV 485
PPPPPPP +Q PPPPPPP PPLP +++E + A+ K +KV
Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGA----KLRKV 404
Query: 486 KKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLME 527
+ ++ N++ D+ R + P LME
Sbjct: 405 SRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLME 446
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/129 (30%), Positives = 53/129 (41%), Gaps = 29/129 (22%)
Query: 353 DKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPR----------HSPWSSPK 402
+++R +RL+ ++Q+ W+R SS S S P
Sbjct: 231 ERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG 290
Query: 403 L-----PKKVQTVRSRPLSPVATPPPPPPPPPP-------PPPSSQRLP-------PPPP 443
L P + + + L P+A PPPPP PP P PPP P PPPP
Sbjct: 291 LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP 350
Query: 444 PPPPPLPEK 452
PPPPPLP +
Sbjct: 351 PPPPPLPNQ 359
Score = 32.0 bits (71), Expect = 1.5
Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 4/133 (3%)
Query: 15 SIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLT-EKTPTGTFSREAL-MAY 72
S +E E+ E+ ++ E E E +E +R L ++ L E+ +E L
Sbjct: 136 SQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERER 195
Query: 73 WEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEEEEEESQEEEEEE 132
E+E Q+ LE++ E + E +E + E + + E + E +E E QE+ E E
Sbjct: 196 QERERQERLERQERLERQERLERQERLDRERQERQERERL-ERLERERQERERQEQLERE 254
Query: 133 DSD-EEERTIETA 144
+ E ER I +A
Sbjct: 255 QLEWERERRISSA 267
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 68.2 bits (165), Expect = 2e-11
Identities = 32/68 (47%), Positives = 36/68 (52%), Gaps = 7/68 (10%)
Query: 382 RGTPSSSPYVSP--RHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLP 439
R P P+ P H PW P+ + P P A P PPP PPPPPPP + LP
Sbjct: 308 RPPPIRPPFSHPISAHLPWYFQPPPRPLP-----PRPPAAQPRPPPSPPPPPPPPASPLP 362
Query: 440 PPPPPPPP 447
PPPPPPPP
Sbjct: 363 PPPPPPPP 370
Score = 47.8 bits (112), Expect = 3e-05
Identities = 31/103 (30%), Positives = 42/103 (40%), Gaps = 34/103 (33%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKK-VQTVRSRPLSPVATPP--------- 422
P + T W PY++ W + K+ ++ ++S P T P
Sbjct: 272 PGIYTATW--------PYLN-----WIASKIGSNALRMIQSATPPPPTTRPPPIRPPFSH 318
Query: 423 -----------PPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKL 454
PPP P PP PP++Q PPP PPPPPP P L
Sbjct: 319 PISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASPL 361
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 67.4 bits (163), Expect = 3e-11
Identities = 32/68 (47%), Positives = 35/68 (51%), Gaps = 7/68 (10%)
Query: 382 RGTPSSSPYVSP--RHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLP 439
R P P+ P H PW P+ + P P A P PPP PPPPPPP LP
Sbjct: 242 RPPPIRPPFSHPLSAHLPWYFQPPPRPLP-----PRPPAAQPRPPPSPPPPPPPPPSPLP 296
Query: 440 PPPPPPPP 447
PPPPPPPP
Sbjct: 297 PPPPPPPP 304
Score = 47.8 bits (112), Expect = 3e-05
Identities = 31/103 (30%), Positives = 42/103 (40%), Gaps = 34/103 (33%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKK-VQTVRSRPLSPVATPP--------- 422
P + T W PY++ W + K+ ++ ++S P T P
Sbjct: 206 PGIYTATW--------PYLN-----WIASKIGSNALRMIQSATPPPPTTRPPPIRPPFSH 252
Query: 423 -----------PPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKL 454
PPP P PP PP++Q PPP PPPPPP P L
Sbjct: 253 PLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPL 295
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 66.6 bits (161), Expect = 5e-11
Identities = 33/66 (50%), Positives = 36/66 (54%), Gaps = 14/66 (21%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444
PS SP VS LP K + ++ PPPPPPPPPPPP PPPPPP
Sbjct: 2377 PSGSPSVS---------SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP-----PPPPPP 2422
Query: 445 PPPPLP 450
PPPPLP
Sbjct: 2423 PPPPLP 2428
Score = 52.8 bits (125), Expect = 8e-07
Identities = 30/72 (41%), Positives = 34/72 (47%), Gaps = 7/72 (9%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPP 442
G+PS S + + S L Q P P PPPPPPPPPP LPPP
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP-------LPPPT 2431
Query: 443 PPPPPPLPEKKL 454
P P LP+KKL
Sbjct: 2432 SPKPTILPKKKL 2443
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/151 (23%), Positives = 54/151 (35%), Gaps = 9/151 (5%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPP 432
P +K+ PSS + P + PKK QT S P P PP P P
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 433 PSSQRLPPPPPPPPPPLPEKK--LITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPN 490
+ Q +P P P P ++ L +I + K Q + + G+ G
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA------- 936
Query: 491 SILKEIKNSLRSVQEKKMEDSSRPSTPQRSA 521
SI + N + + + S P P + A
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Score = 35.8 bits (81), Expect = 0.10
Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 19/124 (15%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPP----PPPPPP------- 432
TP P + + P QT ++P S + P PPP P PPP
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 433 -----PSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKK 487
P S + PP P P P P++ T+ ++ Q SA+ + Q K +
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ---QPGSAKPSAQQPSPAKPSAQQST 555
Query: 488 QPNS 491
+P S
Sbjct: 556 KPVS 559
Score = 34.3 bits (77), Expect = 0.30
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 9/108 (8%)
Query: 411 RSRPLSPVATPPPPPPPPPP--PPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQES 468
+S P +P+ P P PP PP S+ + PP P +P KK AE ++ +
Sbjct: 957 QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK---SIPVKKETKAPAAEKLEPKAE 1013
Query: 469 AQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPST 516
++ + +KK + K S+ E + ++V K+E S +P +
Sbjct: 1014 QAPTVKRTETEKKPPPI-KDSKSLTAEPQ---KAVLPTKLEKSPKPES 1057
Score = 33.9 bits (76), Expect = 0.39
Identities = 113/546 (20%), Positives = 210/546 (38%), Gaps = 121/546 (22%)
Query: 43 DRNLPVGLRQKSLTEKTPTGTFS-----REALMAYWEKESQKLLEK--ERLGECGKVAED 95
++++ GL++ S ++++ + S +++ E ++ L ++ E+ + +V+ +
Sbjct: 1385 EKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPE 1444
Query: 96 KEESEEELIFTESNSEVSEEVYTEEEEEESQEEEEEEDSDEEERTIETAKG--------- 146
+ + +E+ T+S SE E +EEE +ESQEE ++ + ++ I ++K
Sbjct: 1445 QPKDQEK---TQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVD 1501
Query: 147 --INGTVNYDSV----NSDNSKPKIFKSQIENINLTNGSNGRNTESPAA--IHPCGNPTV 198
YDSV S+NS P + + ++ ++ + +S + +
Sbjct: 1502 DITTRREPYDSVEESSESENS-PVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI 1560
Query: 199 IEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDN---TVVKTFSLA------- 248
IE + D+ S D E N ++ I++ T ++ E K T K L
Sbjct: 1561 IEMSADEDASGSED-DEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSI 1619
Query: 249 --------NTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTE 300
+ H +D A + LK E + E +TG G L + ++ N+ + +
Sbjct: 1620 DEDAGRRHSWHDEDDEAFDESPELKYRE-TKSQESEELVVTGGGGLRRFKTIELNSTIAD 1678
Query: 301 LRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRL 360
K E++ Y E P + M S+ D+ R
Sbjct: 1679 -------------------KYSAESSQKKTSLYFDE--EPELEMESLTDSPEDRSRG--- 1714
Query: 361 QEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVAT 420
+G +L + GT +S VS S KK ++ + R A
Sbjct: 1715 ---------EGSSSLHASSFTPGTSPTS--VSSLDEDSDSSPSHKKGESKQQRK----AR 1759
Query: 421 PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKK 480
P P P SS+ E++L R E++K+QE QR ++ Q+K
Sbjct: 1760 HRPHGPLLPTIEDSSE--------------EEEL--REEEELLKEQEK-QREIEQQQRKS 1802
Query: 481 KGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRV 540
KK KK K+ LR+ + ++ RP TP NL S ++L++
Sbjct: 1803 SSKKSKKD--------KDELRAQRRRE-----RPKTPP----SNLSPIEDASPTEELRQA 1845
Query: 541 EVPEAL 546
E L
Sbjct: 1846 AEMEEL 1851
Score = 33.9 bits (76), Expect = 0.39
Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 29/100 (29%)
Query: 385 PSSSPYVSPRHSPWSSPK---LPKKVQTVRSR-------------------------PLS 416
P P P P +SPK LPKK TV S P++
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476
Query: 417 PVATPPPPPPPPPPPP-PSSQRLPPPPPPPPPPLPEKKLI 455
+ T PPP PP P PS P P PP+ K +I
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVI 2516
Score = 32.7 bits (73), Expect = 0.88
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 18/123 (14%)
Query: 413 RPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLIT---RNIAEVIKQQESA 469
R + P + P P P P SSQ+ PP E+++ T + I E +K+ S
Sbjct: 1123 RKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM 1182
Query: 470 QR--ALQNGQKKKKGKKVKKQPNSILKEIK------------NSLRSVQEKKMEDSSRPS 515
++ + +K++ K++K S L+E K +RS ++K + + +P
Sbjct: 1183 EKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP- 1241
Query: 516 TPQ 518
TP+
Sbjct: 1242 TPE 1244
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 6/76 (7%)
Query: 381 QRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPP----PPPPPPPPPPPSSQ 436
Q+ TP P P H S P K S P+A P PP PP P +Q
Sbjct: 307 QQPTPGKPPAQQPGHE--KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364
Query: 437 RLPPPPPPPPPPLPEK 452
L P PP EK
Sbjct: 365 PLGPAKPPAQQTGSEK 380
Score = 32.0 bits (71), Expect = 1.5
Identities = 36/153 (23%), Positives = 56/153 (36%), Gaps = 36/153 (23%)
Query: 388 SPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPP 447
+P+ S S + KK + V+ P PP PP P +P P
Sbjct: 174 NPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP-----IPKQQGPGRD 228
Query: 448 PLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKK 507
PL QQ+ +++ + Q +K+K QP K I+ ++ Q
Sbjct: 229 PL---------------QQDGTPKSISSQQP----EKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 508 -----MEDSSRPSTPQRSAHENLMEAIRGSSIK 535
D+SRP T Q + +RG S+K
Sbjct: 270 AKLPLQRDASRPQTKQ-------ADIVRGESVK 295
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/83 (24%), Positives = 28/83 (33%)
Query: 365 QQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPP 424
QQ G P + + + P P P + P++ + P P + PP
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 425 PPPPPPPPPSSQRLPPPPPPPPP 447
P PP Q P P P P
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQP 524
Score = 31.2 bits (69), Expect = 2.6
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Query: 15 SIDEDELLASLSAEELKELERE-LEDIEPDRNLPVGLRQKSLTEKTPTGTFSREALMAYW 73
S + + SL +E ELE E L D DR+ G + TP GT
Sbjct: 1681 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTP-GTSPTSVSSLDE 1739
Query: 74 EKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEEEEEESQEEEEEED 133
+ +S +K GE + + + L+ T +S EE+ EEEE +E+E++ +
Sbjct: 1740 DSDSSPSHKK---GESKQQRKARHRPHGPLLPTIEDSSEEEEL--REEEELLKEQEKQRE 1794
Query: 134 SDEEERTIETAK 145
++++R + K
Sbjct: 1795 IEQQQRKSSSKK 1806
Score = 30.8 bits (68), Expect = 3.3
Identities = 24/93 (25%), Positives = 33/93 (35%), Gaps = 19/93 (20%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPP- 431
P L+T P ++ + SP PKK + LS P PPP P
Sbjct: 659 PKLKT------APVTTTSAVSKSSPQPQQTSPKK-DAAPKQDLSKAPEPKKPPPLVKQPT 711
Query: 432 -----------PPSSQRLPPPPPPPPPPLPEKK 453
PP + L P PP P +P ++
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Score = 29.3 bits (64), Expect = 9.7
Identities = 22/73 (30%), Positives = 27/73 (36%), Gaps = 9/73 (12%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPP---PPPPPPPSSQ---- 436
TP + P S P+ K+ VR + P P PP P P PP+ Q
Sbjct: 264 TPQTDHAKLPLQRDASRPQT-KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322
Query: 437 -RLPPPPPPPPPP 448
P P PP P
Sbjct: 323 KSQPGPAKPPAQP 335
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 66.6 bits (161), Expect = 5e-11
Identities = 33/66 (50%), Positives = 36/66 (54%), Gaps = 14/66 (21%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444
PS SP VS LP K + ++ PPPPPPPPPPPP PPPPPP
Sbjct: 2377 PSGSPSVS---------SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP-----PPPPPP 2422
Query: 445 PPPPLP 450
PPPPLP
Sbjct: 2423 PPPPLP 2428
Score = 52.8 bits (125), Expect = 8e-07
Identities = 30/72 (41%), Positives = 34/72 (47%), Gaps = 7/72 (9%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPP 442
G+PS S + + S L Q P P PPPPPPPPPP LPPP
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP-------LPPPT 2431
Query: 443 PPPPPPLPEKKL 454
P P LP+KKL
Sbjct: 2432 SPKPTILPKKKL 2443
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/151 (23%), Positives = 54/151 (35%), Gaps = 9/151 (5%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPP 432
P +K+ PSS + P + PKK QT S P P PP P P
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 433 PSSQRLPPPPPPPPPPLPEKK--LITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPN 490
+ Q +P P P P ++ L +I + K Q + + G+ G
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA------- 936
Query: 491 SILKEIKNSLRSVQEKKMEDSSRPSTPQRSA 521
SI + N + + + S P P + A
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Score = 35.8 bits (81), Expect = 0.10
Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 19/124 (15%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPP----PPPPPP------- 432
TP P + + P QT ++P S + P PPP P PPP
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 433 -----PSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKK 487
P S + PP P P P P++ T+ ++ Q SA+ + Q K +
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ---QPGSAKPSAQQPSPAKPSAQQST 555
Query: 488 QPNS 491
+P S
Sbjct: 556 KPVS 559
Score = 34.3 bits (77), Expect = 0.30
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 9/108 (8%)
Query: 411 RSRPLSPVATPPPPPPPPPP--PPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQES 468
+S P +P+ P P PP PP S+ + PP P +P KK AE ++ +
Sbjct: 957 QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK---SIPVKKETKAPAAEKLEPKAE 1013
Query: 469 AQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPST 516
++ + +KK + K S+ E + ++V K+E S +P +
Sbjct: 1014 QAPTVKRTETEKKPPPI-KDSKSLTAEPQ---KAVLPTKLEKSPKPES 1057
Score = 33.9 bits (76), Expect = 0.39
Identities = 113/546 (20%), Positives = 210/546 (38%), Gaps = 121/546 (22%)
Query: 43 DRNLPVGLRQKSLTEKTPTGTFS-----REALMAYWEKESQKLLEK--ERLGECGKVAED 95
++++ GL++ S ++++ + S +++ E ++ L ++ E+ + +V+ +
Sbjct: 1385 EKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPE 1444
Query: 96 KEESEEELIFTESNSEVSEEVYTEEEEEESQEEEEEEDSDEEERTIETAKG--------- 146
+ + +E+ T+S SE E +EEE +ESQEE ++ + ++ I ++K
Sbjct: 1445 QPKDQEK---TQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVD 1501
Query: 147 --INGTVNYDSV----NSDNSKPKIFKSQIENINLTNGSNGRNTESPAA--IHPCGNPTV 198
YDSV S+NS P + + ++ ++ + +S + +
Sbjct: 1502 DITTRREPYDSVEESSESENS-PVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI 1560
Query: 199 IEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDN---TVVKTFSLA------- 248
IE + D+ S D E N ++ I++ T ++ E K T K L
Sbjct: 1561 IEMSADEDASGSED-DEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSI 1619
Query: 249 --------NTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLTE 300
+ H +D A + LK E + E +TG G L + ++ N+ + +
Sbjct: 1620 DEDAGRRHSWHDEDDEAFDESPELKYRE-TKSQESEELVVTGGGGLRRFKTIELNSTIAD 1678
Query: 301 LRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRL 360
K E++ Y E P + M S+ D+ R
Sbjct: 1679 -------------------KYSAESSQKKTSLYFDE--EPELEMESLTDSPEDRSRG--- 1714
Query: 361 QEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVAT 420
+G +L + GT +S VS S KK ++ + R A
Sbjct: 1715 ---------EGSSSLHASSFTPGTSPTS--VSSLDEDSDSSPSHKKGESKQQRK----AR 1759
Query: 421 PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKK 480
P P P SS+ E++L R E++K+QE QR ++ Q+K
Sbjct: 1760 HRPHGPLLPTIEDSSE--------------EEEL--REEEELLKEQEK-QREIEQQQRKS 1802
Query: 481 KGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRV 540
KK KK K+ LR+ + ++ RP TP NL S ++L++
Sbjct: 1803 SSKKSKKD--------KDELRAQRRRE-----RPKTPP----SNLSPIEDASPTEELRQA 1845
Query: 541 EVPEAL 546
E L
Sbjct: 1846 AEMEEL 1851
Score = 33.9 bits (76), Expect = 0.39
Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 29/100 (29%)
Query: 385 PSSSPYVSPRHSPWSSPK---LPKKVQTVRSR-------------------------PLS 416
P P P P +SPK LPKK TV S P++
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476
Query: 417 PVATPPPPPPPPPPPP-PSSQRLPPPPPPPPPPLPEKKLI 455
+ T PPP PP P PS P P PP+ K +I
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVI 2516
Score = 32.7 bits (73), Expect = 0.88
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 18/123 (14%)
Query: 413 RPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLIT---RNIAEVIKQQESA 469
R + P + P P P P SSQ+ PP E+++ T + I E +K+ S
Sbjct: 1123 RKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM 1182
Query: 470 QR--ALQNGQKKKKGKKVKKQPNSILKEIK------------NSLRSVQEKKMEDSSRPS 515
++ + +K++ K++K S L+E K +RS ++K + + +P
Sbjct: 1183 EKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP- 1241
Query: 516 TPQ 518
TP+
Sbjct: 1242 TPE 1244
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 6/76 (7%)
Query: 381 QRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPP----PPPPPPPPPPPSSQ 436
Q+ TP P P H S P K S P+A P PP PP P +Q
Sbjct: 307 QQPTPGKPPAQQPGHE--KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364
Query: 437 RLPPPPPPPPPPLPEK 452
L P PP EK
Sbjct: 365 PLGPAKPPAQQTGSEK 380
Score = 32.0 bits (71), Expect = 1.5
Identities = 36/153 (23%), Positives = 56/153 (36%), Gaps = 36/153 (23%)
Query: 388 SPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPP 447
+P+ S S + KK + V+ P PP PP P +P P
Sbjct: 174 NPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP-----IPKQQGPGRD 228
Query: 448 PLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKK 507
PL QQ+ +++ + Q +K+K QP K I+ ++ Q
Sbjct: 229 PL---------------QQDGTPKSISSQQP----EKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 508 -----MEDSSRPSTPQRSAHENLMEAIRGSSIK 535
D+SRP T Q + +RG S+K
Sbjct: 270 AKLPLQRDASRPQTKQ-------ADIVRGESVK 295
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/83 (24%), Positives = 28/83 (33%)
Query: 365 QQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPP 424
QQ G P + + + P P P + P++ + P P + PP
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 425 PPPPPPPPPSSQRLPPPPPPPPP 447
P PP Q P P P P
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQP 524
Score = 31.2 bits (69), Expect = 2.6
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Query: 15 SIDEDELLASLSAEELKELERE-LEDIEPDRNLPVGLRQKSLTEKTPTGTFSREALMAYW 73
S + + SL +E ELE E L D DR+ G + TP GT
Sbjct: 1681 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTP-GTSPTSVSSLDE 1739
Query: 74 EKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEEEEEESQEEEEEED 133
+ +S +K GE + + + L+ T +S EE+ EEEE +E+E++ +
Sbjct: 1740 DSDSSPSHKK---GESKQQRKARHRPHGPLLPTIEDSSEEEEL--REEEELLKEQEKQRE 1794
Query: 134 SDEEERTIETAK 145
++++R + K
Sbjct: 1795 IEQQQRKSSSKK 1806
Score = 30.8 bits (68), Expect = 3.3
Identities = 24/93 (25%), Positives = 33/93 (35%), Gaps = 19/93 (20%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPP- 431
P L+T P ++ + SP PKK + LS P PPP P
Sbjct: 659 PKLKT------APVTTTSAVSKSSPQPQQTSPKK-DAAPKQDLSKAPEPKKPPPLVKQPT 711
Query: 432 -----------PPSSQRLPPPPPPPPPPLPEKK 453
PP + L P PP P +P ++
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Score = 29.3 bits (64), Expect = 9.7
Identities = 22/73 (30%), Positives = 27/73 (36%), Gaps = 9/73 (12%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPP---PPPPPPPSSQ---- 436
TP + P S P+ K+ VR + P P PP P P PP+ Q
Sbjct: 264 TPQTDHAKLPLQRDASRPQT-KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322
Query: 437 -RLPPPPPPPPPP 448
P P PP P
Sbjct: 323 KSQPGPAKPPAQP 335
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 65.5 bits (158), Expect = 1e-10
Identities = 33/87 (37%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 374 NLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPP----PPPPPPP 429
N T GT S P+ + + +SP P+ PL P PP PPPPPP
Sbjct: 528 NTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP 587
Query: 430 PPPPSSQRLPPPPPPPPPPLPEKKLIT 456
PPP S+ + PPPPPPPP+ +T
Sbjct: 588 PPPGSAGMMYAPPPPPPPPMDPSNFVT 614
Score = 49.7 bits (117), Expect = 7e-06
Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 23/92 (25%)
Query: 414 PLSPVATPPPPPPPP---PPPPPSS--------QRLPPPPPPP------PPPLPEKKLIT 456
P P+ PPPPPPP PPPPPS Q+ PPPPPPP PLP ++ T
Sbjct: 471 PPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT 530
Query: 457 RNIAEVIK------QQESAQRALQNGQKKKKG 482
QQ+ A A G + +G
Sbjct: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQG 562
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/82 (34%), Positives = 32/82 (39%), Gaps = 10/82 (12%)
Query: 380 WQRGTPSSS-PYVS--------PRHSPWSSPK-LPKKVQTVRSRPLSPVATPPPPPPPPP 429
W PS S PY P P S P LP P+ PPPP P
Sbjct: 368 WMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQP 427
Query: 430 PPPPSSQRLPPPPPPPPPPLPE 451
PPPP +Q PP PPP+ +
Sbjct: 428 PPPPMNQGPHPPGHHGPPPMDQ 449
Score = 30.8 bits (68), Expect = 3.3
Identities = 25/100 (25%), Positives = 32/100 (32%), Gaps = 31/100 (31%)
Query: 361 QEQKQQEGYDGGPNLRTKVWQRGTPSSSPY---VSPRHSPWSSPKLPKKVQTVRSRPLSP 417
Q+Q G P ++ G P+ P V P P + P P +P
Sbjct: 546 QQQAAAAASPGAPQMQ------GNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAP 599
Query: 418 VATPPPP----------------------PPPPPPPPPSS 435
PPPP PP PPPPPP +
Sbjct: 600 PPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN 639
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 65.5 bits (158), Expect = 1e-10
Identities = 33/74 (44%), Positives = 42/74 (56%), Gaps = 6/74 (8%)
Query: 386 SSSPYVSPRHSPWSSPKLPKKVQ-----TVRSRPLSPVATPPPPPPPPPPPPPSSQRLPP 440
SS+P+ R + SP +P K T + P + PPPPPPPPPPPP + PP
Sbjct: 1978 SSAPH-QLRLANMLSPNMPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPP 2036
Query: 441 PPPPPPPPLPEKKL 454
PPPP PPPLP ++
Sbjct: 2037 PPPPLPPPLPNAEV 2050
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/43 (51%), Positives = 24/43 (55%), Gaps = 7/43 (16%)
Query: 414 PLSPVATPPPP---PPPPPPPPPSSQRLPPPPPPPPPPLPEKK 453
P P PPPP PPPPPPPPP LPPP P P +K+
Sbjct: 2018 PPPPPPPPPPPLALPPPPPPPPP----LPPPLPNAEVPSDQKQ 2056
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 10/76 (13%)
Query: 414 PLSPVATPPPPPPPPPPPP-------PSSQRLPPPPPPPPPPL--PEKKLITRNI-AEVI 463
P P+A PPPPPPPPP PP PS Q+ PP L P+ I NI +E +
Sbjct: 2025 PPPPLALPPPPPPPPPLPPPLPNAEVPSDQKQPPVTMETTKRLSWPQSTGICSNIKSEPL 2084
Query: 464 KQQESAQRALQNGQKK 479
+E + + G K+
Sbjct: 2085 SFEEGLSSSCELGMKQ 2100
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 65.1 bits (157), Expect = 2e-10
Identities = 35/92 (38%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
Query: 363 QKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPP 422
++ +E YD + + P P P P S P K+ S PL P
Sbjct: 1938 RQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP 1997
Query: 423 PPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKL 454
PPPPPPPPPPP PPPPPPPP P+ +L
Sbjct: 1998 PPPPPPPPPPP-----PPPPPPPPSAPPQVQL 2024
Score = 51.2 bits (121), Expect = 2e-06
Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 31/128 (24%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPP 443
TP + + S SSP L ++ S P P+ PPPPPPPPPPPPSS
Sbjct: 3084 TPPGAGMLGFPTSATSSPAL-----SLSSAPTKPLLQTPPPPPPPPPPPPSSS------- 3131
Query: 444 PPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSV 503
+ Q++ Q+ ++ +K+ K KVKK L+ K
Sbjct: 3132 -------------------LSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPK 3172
Query: 504 QEKKMEDS 511
+E+K+ +
Sbjct: 3173 KEEKISSA 3180
Score = 29.3 bits (64), Expect = 9.7
Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 10/108 (9%)
Query: 429 PPPPPSSQRLPPPPPPPPPPLPEKKLITR---NI----AEVIKQQESAQRALQNGQKKKK 481
P P Q+ PPPP KL+ + NI +++K S + A +K +K
Sbjct: 1763 PQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPEK 1822
Query: 482 GKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAI 529
K+ LKE K++ + +K +E S P A N +A+
Sbjct: 1823 PKQEFISEGEGLKEGKDTKK---QKSLEPSIPPPRIASGARGNAAKAL 1867
Score = 29.3 bits (64), Expect = 9.7
Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 6/83 (7%)
Query: 370 DGGPNLRTKVWQRGTPSSSPYV-SPRHSPW-SSPKLPKKVQTVRSRPLSPVATPPPPPPP 427
D N G+ +S+P + SP+ P +SPK + + SP + P P
Sbjct: 2326 DAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALP 2385
Query: 428 ----PPPPPPSSQRLPPPPPPPP 446
PP +S P P P PP
Sbjct: 2386 LASTSSDPPQASTAQPQPQPQPP 2408
Score = 29.3 bits (64), Expect = 9.7
Identities = 23/107 (21%), Positives = 38/107 (35%), Gaps = 2/107 (1%)
Query: 412 SRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQR 471
S PL P +P P P P P P P PP K + Q S +
Sbjct: 2343 STPLIP--SPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQ 2400
Query: 472 ALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQ 518
Q K+ + + + P++ + +S + +++S P Q
Sbjct: 2401 PQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQ 2447
Score = 29.3 bits (64), Expect = 9.7
Identities = 20/70 (28%), Positives = 26/70 (37%), Gaps = 11/70 (15%)
Query: 393 PRHSPWSSPKLPKKVQTVRSRPLSPVATPPP--------PPPPPPPPPPSSQRLPPPPPP 444
P P S P T + PL+ ++ PP P P PP P Q + PP
Sbjct: 2364 PAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQP---QLIGRPPSA 2420
Query: 445 PPPPLPEKKL 454
P+P L
Sbjct: 2421 SQTPVPSSPL 2430
>gi|158534059 formin binding protein 4 [Homo sapiens]
Length = 1017
Score = 65.1 bits (157), Expect = 2e-10
Identities = 123/548 (22%), Positives = 205/548 (37%), Gaps = 95/548 (17%)
Query: 28 EELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGTFSREALMAYWEKESQKLLEKER-L 86
E KE+ ++ + G+ L P G E E+ +K++ KE +
Sbjct: 299 EVKKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEE------ERWRRKVICKEEPV 352
Query: 87 GECGKVAEDKEES----EEELIFTESNSEVSEEVYTEEEEEESQEEEEEEDSDEEERTIE 142
E + + EE+ + + I ++ + S+E + EEEEE+D+ E E +E
Sbjct: 353 SEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLE 412
Query: 143 TAKGI-------NGTVNYDSVNSDNSKP----------------KIF--KSQIENINLTN 177
K +G+V+ S SD S+P K+F + E+ + ++
Sbjct: 413 RKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSS 472
Query: 178 GSNGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALK 237
GR+T G + + +KI N EV + E I QT + E +
Sbjct: 473 SKTGRDTPEN------GETAIGAENSEKIDENSDKEMEVE-ESPEKIKVQTTPKVEE--E 523
Query: 238 DNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTV 297
+ + LANT + I N H+ + E+ + AL N +
Sbjct: 524 QDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWRE-----GALNGNYL 578
Query: 298 LTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQ-- 355
+L Q E +K + N T H++ R + + +
Sbjct: 579 KRKL-----------QDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFP 627
Query: 356 -RQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHS-PWSSPKLPKKVQTVRSR 413
++ +E + QE D +T + GT S+S S + +V +
Sbjct: 628 DGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLM 687
Query: 414 PLSPVAT---------PPPPP---PPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAE 461
PL+P T PP P PPPPPPPP S PPPPPPPPPP + + I E
Sbjct: 688 PLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPES---PPPPPPPPPPAEDGE-----IQE 739
Query: 462 VIKQQESAQRALQNGQKKKKGKKVKKQPNSILKE--------IKNSLRSVQEKKMEDSSR 513
V + E ++ G ++ K Q + + +S + ++ K E S+
Sbjct: 740 VEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEIST- 798
Query: 514 PSTPQRSA 521
+ QRSA
Sbjct: 799 -AVVQRSA 805
Score = 59.3 bits (142), Expect = 9e-09
Identities = 47/145 (32%), Positives = 65/145 (44%), Gaps = 31/145 (21%)
Query: 407 VQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQ 466
+Q V++R P AT PPPPPPPPPP PPPP P PP PEK
Sbjct: 888 LQPVQARGAVPTATIIEPPPPPPPPPP-----PPPPAPKMPP-PEK-------------- 927
Query: 467 ESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSS---RPSTPQRSAHE 523
+ G+K K K K P S++K+ ++ R + E+ SS R ST Q+ E
Sbjct: 928 ------TKKGRKDKAKKSKTKMP-SLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEE 980
Query: 524 -NLMEAIRGSSIKQLKRVEVPEALR 547
+ + G + + +PE R
Sbjct: 981 WKQQQLVSGMAERNANFEALPEDWR 1005
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 64.3 bits (155), Expect = 3e-10
Identities = 40/125 (32%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 388 SPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPP 447
SP +P +P +P LP + + PL PPPPPPPPPP PPPPPPPPP
Sbjct: 553 SPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPP 612
Query: 448 PLPEKKLITRN--IAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQE 505
P L R+ + +K ++ Q + K + ++ E+ N + +QE
Sbjct: 613 GGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTEL-NDEKVLQE 671
Query: 506 KKMED 510
M D
Sbjct: 672 LDMSD 676
Score = 53.9 bits (128), Expect = 4e-07
Identities = 27/66 (40%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444
P++ P +P +P P LP + P +P PP P P PPP P PPPPP
Sbjct: 532 PAAEP--APGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPP 589
Query: 445 PPPPLP 450
PPPP P
Sbjct: 590 PPPPPP 595
Score = 49.7 bits (117), Expect = 7e-06
Identities = 49/202 (24%), Positives = 68/202 (33%), Gaps = 34/202 (16%)
Query: 281 TGKGILAIMRALQHNTVLTELRFH---NQRHIMGSQVEMEIVKLLKENTTLLR------- 330
T +L M LQ L R N+ +++E ++ + KE TL
Sbjct: 393 TKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSESTA 452
Query: 331 LGYHFELPGPRMSMTSILTRNMDKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPY 390
+G P P + + TR + + E+K GP + ++P
Sbjct: 453 MGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPS 512
Query: 391 VSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPP------------------------P 426
+P P + P A PPPPP P
Sbjct: 513 GGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSP 572
Query: 427 PPPPPPPSSQRLPPPPPPPPPP 448
PPP PP LPPPPPPPPPP
Sbjct: 573 EPPPAPPLPGDLPPPPPPPPPP 594
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/88 (35%), Positives = 35/88 (39%), Gaps = 36/88 (40%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPP---------------P 427
G P+ SP SP +P + P +P A PPPPPP P
Sbjct: 520 GVPTGSP--SPDLAPAAEP--------------APGAAPPPPPPLPGLPSPQEAPPSAPP 563
Query: 428 PPPPPPSSQRLPPPPP-----PPPPPLP 450
PP P S PP PP PPPPP P
Sbjct: 564 QAPPLPGSPEPPPAPPLPGDLPPPPPPP 591
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 63.9 bits (154), Expect = 4e-10
Identities = 31/55 (56%), Positives = 37/55 (67%), Gaps = 7/55 (12%)
Query: 401 PKLPKKVQTVR-SRPLSPVAT----PPPPPPPPPPPPPSSQRLPPPPPPPPPPLP 450
P LP + ++ + P+ PV+ PPPPPPPPP PPPSS PPPPPPPPPLP
Sbjct: 656 PPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSS--AGPPPPPPPPPLP 708
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPP--------PPPPPPPPSSQ 436
P+S P P S S + V + P P PPPPP PPPPPPPP
Sbjct: 649 PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLP 708
Query: 437 RLPPPP----PPPPPPLP 450
P PP PPP PP P
Sbjct: 709 NSPAPPNPGGPPPAPPPP 726
Score = 52.0 bits (123), Expect = 1e-06
Identities = 23/40 (57%), Positives = 26/40 (65%), Gaps = 4/40 (10%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQRLP----PPPPPPPPPL 449
PL P ++ PPPPPPPPP P+S P PPP PPPP L
Sbjct: 689 PLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGL 728
Score = 51.6 bits (122), Expect = 2e-06
Identities = 34/76 (44%), Positives = 37/76 (48%), Gaps = 10/76 (13%)
Query: 383 GTPSSSPYVSPRHSPWSS-PKLPKKVQTVRSRPLSPVATPPPPPPPPP----PPPPSSQR 437
G S SP +P P S+ P LP P A PPPPPPPPP P PP+
Sbjct: 661 GLGSLSP--APPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718
Query: 438 LPPPPPPP---PPPLP 450
PP PPPP PPP P
Sbjct: 719 PPPAPPPPGLAPPPPP 734
Score = 47.4 bits (111), Expect = 3e-05
Identities = 23/51 (45%), Positives = 26/51 (50%), Gaps = 11/51 (21%)
Query: 411 RSRPLSPVATPPPPPPP-----------PPPPPPSSQRLPPPPPPPPPPLP 450
+ + L P PPPPP PP PP S+ PPPPPPPPPLP
Sbjct: 641 QQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP 691
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 62.4 bits (150), Expect = 1e-09
Identities = 25/35 (71%), Positives = 26/35 (74%)
Query: 416 SPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLP 450
SP ATP P PPPPPPP P Q+ PPPPPP PPP P
Sbjct: 13 SPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGP 47
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 17/69 (24%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPP 442
G P SP +P P P P +P PPPPPPP PPP P P
Sbjct: 8 GRPGESPGATPAPGPPPPP------------PPAPPQQQPPPPPPPAPPPG-----PGPA 50
Query: 443 PPPPPPLPE 451
PP PP E
Sbjct: 51 PPQHPPRAE 59
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Query: 404 PKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPP---PPPPPLPEKKLITRNIA 460
P+ V+ P A+P PPPP PP P+S R P P P PL L R ++
Sbjct: 755 PRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLS 814
Query: 461 EVIKQQESAQRALQNG 476
+ ++Q +L +G
Sbjct: 815 RASRPLSASQPSLPHG 830
Score = 38.9 bits (89), Expect = 0.012
Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 9/62 (14%)
Query: 389 PYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPP 448
P SP +P P P + +P PPPPPP PPP P + PP PP
Sbjct: 10 PGESPGATPAPGPPPPPPPAPPQQQP------PPPPPPAPPPGPGPA---PPQHPPRAEA 60
Query: 449 LP 450
LP
Sbjct: 61 LP 62
Score = 33.5 bits (75), Expect = 0.51
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPP-----PPPPSSQRL- 438
P +SPY +P + P LP + + SRPLS P P P P S+ RL
Sbjct: 790 PRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLG 849
Query: 439 PPPPPPPPPPLPEKK-LITRNIAEVIKQQESAQRALQN 475
P P P P+++ + A + Q+SA+ L +
Sbjct: 850 PTPAARAAAPSPDRRDSASPGAAGGLDPQDSARSRLSS 887
Score = 31.2 bits (69), Expect = 2.6
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 412 SRPL-SPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPP 448
+RPL P+A P PPP P+ P PPPP P
Sbjct: 743 ARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASP 780
Score = 30.8 bits (68), Expect = 3.3
Identities = 11/25 (44%), Positives = 15/25 (60%)
Query: 429 PPPPPSSQRLPPPPPPPPPPLPEKK 453
P P + P PPPPPPP P+++
Sbjct: 10 PGESPGATPAPGPPPPPPPAPPQQQ 34
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 61.6 bits (148), Expect = 2e-09
Identities = 23/45 (51%), Positives = 29/45 (64%)
Query: 408 QTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEK 452
Q ++ P PPPPP PPPPPP Q+ PPPPPPPP +P++
Sbjct: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQ 788
Score = 52.0 bits (123), Expect = 1e-06
Identities = 21/38 (55%), Positives = 24/38 (63%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPE 451
P V + PPPP PPPP P Q+L PPPPPPP P+
Sbjct: 946 PSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQ 983
Score = 48.9 bits (115), Expect = 1e-05
Identities = 43/169 (25%), Positives = 65/169 (38%), Gaps = 39/169 (23%)
Query: 400 SPKLPK-KVQTVRSRPLSPVA----------TPPPPPPPPPPPPPSSQRLPPPPP----- 443
+P LP KVQ+ PL P PPPPPPP P PPP Q PPP P
Sbjct: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001
Query: 444 ---------PPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKK-------VKK 487
PPPP + Q Q+ +Q+ + K +++
Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061
Query: 488 QPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQ 536
P+ ++ + S Q + + + S PQ++ E +R +S+ Q
Sbjct: 1062 APSPLM------IHSPQMSQFQSLTHQSPPQQNVQPKKQE-LRAASVVQ 1103
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
Query: 381 QRGTPSSSP---YVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPP-PPPPPPPSSQ 436
Q TP +P +P P +P L + + P P+ TPPP PP P PPP P+ Q
Sbjct: 207 QTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQ 266
Query: 437 RLPPPPP---PPPPPLPEKKLITR 457
+ PP P P+ KK + R
Sbjct: 267 PVQSHPPIIAATPQPVKTKKGVKR 290
Score = 42.7 bits (99), Expect = 8e-04
Identities = 42/198 (21%), Positives = 69/198 (34%), Gaps = 32/198 (16%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPP 432
P+++ ++ Q+ P P P P P+ V + + + PPPP PP P
Sbjct: 964 PSVQQQLQQQPPPPPPPQPQPPPQQQHQPP-PRPVHLQPMQFSTHIQQPPPPQGQQPPHP 1022
Query: 433 PSSQRLPPPPPP----------------------------PPPPLPEKKLITRNIAEVIK 464
P Q+ PPPP P P PL +
Sbjct: 1023 PPGQQ-PPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTH 1081
Query: 465 QQESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHEN 524
Q Q Q+ + V+ QP ++KE K ++ + S RP P+ E+
Sbjct: 1082 QSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHP--ES 1139
Query: 525 LMEAIRGSSIKQLKRVEV 542
+ + ++K V+V
Sbjct: 1140 IKAPVHLPQRPEMKPVDV 1157
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/125 (27%), Positives = 48/125 (38%), Gaps = 5/125 (4%)
Query: 349 TRNMDKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQ 408
T M Q + R + +K+ G + Q TP + P P + P
Sbjct: 169 TEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAV 228
Query: 409 TVRSRPLSPVATPPPPPP--PPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQ 466
T +PV T PP P PPP PP Q PPP P P P+ I + +K +
Sbjct: 229 TPDLIVQTPVMTVVPPQPLQTPPPVPPQPQ---PPPAPAPQPVQSHPPIIAATPQPVKTK 285
Query: 467 ESAQR 471
+ +R
Sbjct: 286 KGVKR 290
Score = 38.9 bits (89), Expect = 0.012
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 9/152 (5%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPP 432
P L + Q S+ P+++ +H+ S P L + SRP + A PP P PP
Sbjct: 833 PELPPHLPQPPEHSTPPHLN-QHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVS 891
Query: 433 PSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKK------KGKKVK 486
P+ + P P PP P+ L Q LQ QK + KV+
Sbjct: 892 PALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQ 951
Query: 487 KQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQ 518
QP L + SVQ++ + P PQ
Sbjct: 952 SQPPPPLPPPPHP--SVQQQLQQQPPPPPPPQ 981
Score = 37.0 bits (84), Expect = 0.047
Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 6/32 (18%)
Query: 422 PPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKK 453
P P P PPPPP PPPPPPP +++
Sbjct: 750 PAPVPQQPPPPPQQ------PPPPPPPQQQQQ 775
Score = 36.6 bits (83), Expect = 0.061
Identities = 58/234 (24%), Positives = 95/234 (40%), Gaps = 44/234 (18%)
Query: 340 PRMSMTSILTRNMDKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYV-SPRHSPW 398
P+MS LT Q+ +Q +KQ+ + V + SP + S SP
Sbjct: 1071 PQMSQFQSLTHQSPPQQN--VQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPS 1128
Query: 399 SSPKLPKKVQTVRS----------RPLS---PVATPPPPPPPPPPPPPSSQRLPPPPPPP 445
P+ PK +++++ +P+ PV PP PPP P ++ P
Sbjct: 1129 LRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQ---KQEPK 1185
Query: 446 PPPLPEKKLITRNI---AEVIKQQ---------------ESAQRALQNGQKKKKGKKVKK 487
P P+K L +N+ A ++++ E +RA + +K+++ K +K
Sbjct: 1186 TPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAR--EKEEREKALKA 1243
Query: 488 QPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRVE 541
Q KE K LR + + ED +R AHE EA R +Q +R E
Sbjct: 1244 QAEHAEKE-KERLRQERMRSREDEDALEQARR-AHE---EARRRQEQQQQQRQE 1292
Score = 30.0 bits (66), Expect = 5.7
Identities = 42/196 (21%), Positives = 68/196 (34%), Gaps = 32/196 (16%)
Query: 361 QEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVAT 420
Q+Q+Q P++ + S P+++ + P P+LP V P+
Sbjct: 771 QQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQ-VPVLEPQLPGSVFDPIGHFTQPILH 829
Query: 421 PPPPPPPPPPPPPSSQRLPP--------PPPPPPPPLPEKKLITRNIAEVIKQQESAQRA 472
P P PP P P PP PP LP++ N A + + + A
Sbjct: 830 LPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPA 889
Query: 473 LQNG--QKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHENLMEAIR 530
+ Q + QP +L +ED P+ P S L
Sbjct: 890 VSPALTQTPLLPQPPMAQPPQVL--------------LEDEEPPAPPLTSMQMQLY---- 931
Query: 531 GSSIKQLKRVEVPEAL 546
++QL++V+ P L
Sbjct: 932 ---LQQLQKVQPPTPL 944
Score = 29.6 bits (65), Expect = 7.4
Identities = 19/62 (30%), Positives = 24/62 (38%), Gaps = 6/62 (9%)
Query: 393 PRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEK 452
P P P P Q + P PPPPP P P+ + PPP P+ E
Sbjct: 757 PPPPPQQPPPPPPPQQQQQPPP------PPPPPSMPQQAAPAMKSSPPPFIATQVPVLEP 810
Query: 453 KL 454
+L
Sbjct: 811 QL 812
Score = 29.3 bits (64), Expect = 9.7
Identities = 20/77 (25%), Positives = 28/77 (36%), Gaps = 10/77 (12%)
Query: 386 SSSPYVSPRHSPWSSPK-LPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444
S P ++ P + K + +K T + P+ PP PP P +R P
Sbjct: 270 SHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVK 329
Query: 445 PPP---------PLPEK 452
PP P PEK
Sbjct: 330 PPKKDVPDSQQHPAPEK 346
Score = 29.3 bits (64), Expect = 9.7
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPE--KKLITRNIAEVIKQQESA-- 469
P+ V++P PPP PPSS + ++ + +AE+ +Q ++
Sbjct: 464 PVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHE 523
Query: 470 QRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQRSAHEN 524
Q A + ++ K KK +K KE V+E K + P P+++ N
Sbjct: 524 QLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP-PPKKTKKNN 577
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 61.6 bits (148), Expect = 2e-09
Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 10/101 (9%)
Query: 383 GTPSSSPYVSPRHSPWSS--PKLPKKVQTVRSRPLSPVA------TPPPPPPPPPPPPPS 434
G+ S P+ P +P P+ PK+ ++ L PV +PPPP PP PPPPP
Sbjct: 175 GSSSPEPWARPSCTPQEGGCPR-PKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPL 233
Query: 435 SQRLPPPPPPPPPPLPEKKLITRNIA-EVIKQQESAQRALQ 474
+Q P PP PPPPP P L + + + ++ Q+ A++
Sbjct: 234 AQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIR 274
Score = 48.1 bits (113), Expect = 2e-05
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 6/49 (12%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEV 462
P +PV + PPP PPPPPPP PPP P PPP P+ ++ ++ V
Sbjct: 299 PGTPVDSLPPPLPPPPPPP------PPPRPVLPPPAPKVEITPEPVSVV 341
Score = 40.0 bits (92), Expect = 0.006
Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 412 SRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLP 450
S LS + P P PPP LPPPPPPPPPP P
Sbjct: 288 SEALSALLPLLPGTPVDSLPPP----LPPPPPPPPPPRP 322
Score = 35.4 bits (80), Expect = 0.14
Identities = 17/42 (40%), Positives = 18/42 (42%)
Query: 401 PKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPP 442
P LP PL P PPPPP P PPP + P P
Sbjct: 296 PLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEP 337
>gi|195947369 junction-mediating and regulatory protein [Homo
sapiens]
Length = 988
Score = 60.8 bits (146), Expect = 3e-09
Identities = 50/150 (33%), Positives = 69/150 (46%), Gaps = 28/150 (18%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLP----------EKKLITRNIAEV- 462
P S P P P PP PPPP PPPPPPPPPPLP EK L + E
Sbjct: 795 PCSVTINPLPSPLPPTPPPPP----PPPPPPPPPPLPVAKDSGPETLEKDLPRKEGNEKR 850
Query: 463 IKQQESAQRA--LQNGQKKKKGKKVKK--------QPNSILKEIKNSLR--SVQEKKMED 510
I + SA A + Q KK++K + +S + E+ SL+ S KK+E
Sbjct: 851 IPKSASAPSAHLFDSSQLVSARKKLRKTAEGLQRRRVSSPMDEVLASLKRGSFHLKKVEQ 910
Query: 511 SSRPSTPQRSAHENLMEAIR-GSSIKQLKR 539
+ P P N++ IR G +K++++
Sbjct: 911 RTLPPFPDEDDSNNILAQIRKGVKLKKVQK 940
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 60.5 bits (145), Expect = 4e-09
Identities = 38/86 (44%), Positives = 41/86 (47%), Gaps = 23/86 (26%)
Query: 389 PYVSPRHSPWSSPKLPKKVQTVRSRPLSP--VATPPPPPPPPPPPPP--------SSQRL 438
P V R +P LP T+ P +P TPPPPPPPPPPPPP S L
Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSL 624
Query: 439 P------PPPP-------PPPPPLPE 451
P PPPP PPPPPLPE
Sbjct: 625 PGGTAISPPPPLSGDATIPPPPPLPE 650
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/80 (42%), Positives = 35/80 (43%), Gaps = 28/80 (35%)
Query: 399 SSPKLPKKVQTVRSRPLSPVATPPPPPP-------------------PPPPPPPSSQRLP 439
S P LP PLS AT PPPPP PPPPP P S R+P
Sbjct: 620 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 679
Query: 440 PPP---------PPPPPPLP 450
PPP PPPPPPLP
Sbjct: 680 PPPPPLPGSAGIPPPPPPLP 699
Score = 51.2 bits (121), Expect = 2e-06
Identities = 30/77 (38%), Positives = 31/77 (40%), Gaps = 13/77 (16%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSP--VATPPPPPP-------PPPPPPPSS 435
P P P P LP P P PPPPPP PPPPP P
Sbjct: 667 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 726
Query: 436 QRLPPPPP----PPPPP 448
+PPPPP PPPPP
Sbjct: 727 PGIPPPPPGMGMPPPPP 743
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/52 (48%), Positives = 26/52 (50%), Gaps = 15/52 (28%)
Query: 414 PLSPVATPPPPP-------PPPPPPPPSSQRLPPPPP--------PPPPPLP 450
P S PPPPP PPPPPP P +PPPPP PPPPP P
Sbjct: 673 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 724
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/68 (44%), Positives = 33/68 (48%), Gaps = 19/68 (27%)
Query: 401 PKLPKKVQTVRSRPLSPVATPPPPP---------PPPPPPPPSSQRLPPPP--------- 442
P LP+ V + S P T PPP PPPPPP P S +PPPP
Sbjct: 646 PPLPEGVG-IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGM 704
Query: 443 PPPPPPLP 450
PPPPPPLP
Sbjct: 705 PPPPPPLP 712
Score = 48.1 bits (113), Expect = 2e-05
Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 10/47 (21%)
Query: 414 PLSPVATPPPPPPP----------PPPPPPSSQRLPPPPPPPPPPLP 450
P S + P PP P PPPP P PPPPPPPPPP P
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP 610
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 22/83 (26%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSP----VATPPPP-------PPPPPPPP 432
+PSS P + P P LP + P P + PPPP PPPPPP
Sbjct: 656 SPSSLPGGTAIPPP---PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP-L 711
Query: 433 PSSQRLPPPPP-------PPPPP 448
P +PPPPP PPPPP
Sbjct: 712 PGGPGIPPPPPFPGGPGIPPPPP 734
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/39 (41%), Positives = 18/39 (46%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEK 452
P P PPPP PPPPP +P P P P+K
Sbjct: 724 PGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKK 762
Score = 29.6 bits (65), Expect = 7.4
Identities = 16/34 (47%), Positives = 16/34 (47%)
Query: 421 PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKL 454
PPPPP PPPP P P P L KKL
Sbjct: 730 PPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKL 763
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 60.5 bits (145), Expect = 4e-09
Identities = 38/86 (44%), Positives = 41/86 (47%), Gaps = 23/86 (26%)
Query: 389 PYVSPRHSPWSSPKLPKKVQTVRSRPLSP--VATPPPPPPPPPPPPP--------SSQRL 438
P V R +P LP T+ P +P TPPPPPPPPPPPPP S L
Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSL 633
Query: 439 P------PPPP-------PPPPPLPE 451
P PPPP PPPPPLPE
Sbjct: 634 PGGTAISPPPPLSGDATIPPPPPLPE 659
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/80 (42%), Positives = 35/80 (43%), Gaps = 28/80 (35%)
Query: 399 SSPKLPKKVQTVRSRPLSPVATPPPPPP-------------------PPPPPPPSSQRLP 439
S P LP PLS AT PPPPP PPPPP P S R+P
Sbjct: 629 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 688
Query: 440 PPP---------PPPPPPLP 450
PPP PPPPPPLP
Sbjct: 689 PPPPPLPGSAGIPPPPPPLP 708
Score = 51.2 bits (121), Expect = 2e-06
Identities = 30/77 (38%), Positives = 31/77 (40%), Gaps = 13/77 (16%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSP--VATPPPPPP-------PPPPPPPSS 435
P P P P LP P P PPPPPP PPPPP P
Sbjct: 676 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 735
Query: 436 QRLPPPPP----PPPPP 448
+PPPPP PPPPP
Sbjct: 736 PGIPPPPPGMGMPPPPP 752
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/52 (48%), Positives = 26/52 (50%), Gaps = 15/52 (28%)
Query: 414 PLSPVATPPPPP-------PPPPPPPPSSQRLPPPPP--------PPPPPLP 450
P S PPPPP PPPPPP P +PPPPP PPPPP P
Sbjct: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 733
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/68 (44%), Positives = 33/68 (48%), Gaps = 19/68 (27%)
Query: 401 PKLPKKVQTVRSRPLSPVATPPPPP---------PPPPPPPPSSQRLPPPP--------- 442
P LP+ V + S P T PPP PPPPPP P S +PPPP
Sbjct: 655 PPLPEGVG-IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGM 713
Query: 443 PPPPPPLP 450
PPPPPPLP
Sbjct: 714 PPPPPPLP 721
Score = 48.1 bits (113), Expect = 2e-05
Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 10/47 (21%)
Query: 414 PLSPVATPPPPPPP----------PPPPPPSSQRLPPPPPPPPPPLP 450
P S + P PP P PPPP P PPPPPPPPPP P
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP 619
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 22/83 (26%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSP----VATPPPP-------PPPPPPPP 432
+PSS P + P P LP + P P + PPPP PPPPPP
Sbjct: 665 SPSSLPGGTAIPPP---PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP-L 720
Query: 433 PSSQRLPPPPP-------PPPPP 448
P +PPPPP PPPPP
Sbjct: 721 PGGPGIPPPPPFPGGPGIPPPPP 743
Score = 32.0 bits (71), Expect = 1.5
Identities = 16/39 (41%), Positives = 18/39 (46%)
Query: 414 PLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEK 452
P P PPPP PPPPP +P P P P+K
Sbjct: 733 PGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKK 771
Score = 29.6 bits (65), Expect = 7.4
Identities = 16/34 (47%), Positives = 16/34 (47%)
Query: 421 PPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKL 454
PPPPP PPPP P P P L KKL
Sbjct: 739 PPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKL 772
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 59.7 bits (143), Expect = 7e-09
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 10/101 (9%)
Query: 353 DKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRS 412
D++ +K+ +E+K +EG + V + P++ + P +P P
Sbjct: 363 DEEEEKKEEEEKDKEGEE---KEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP---- 415
Query: 413 RPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKK 453
PL P +T PPPP PPPPPP S PP P PPPPP E++
Sbjct: 416 -PLPPPSTSPPPPLCPPPPPPVSP--PPLPSPPPPPAQEEQ 453
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/68 (42%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 386 SSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPP 445
SS +PR P P KV+ S L P T PP P P P PS R P PP
Sbjct: 536 SSRVIKTPRRFMDEDPPKPPKVEV--SPVLRPPITTSPPVPQEPAPVPSPPR-APTPPST 592
Query: 446 PPPLPEKK 453
P PLPEK+
Sbjct: 593 PVPLPEKR 600
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 11/81 (13%)
Query: 381 QRGTPSSSPYVSPRHSPWSSP-KLPKKVQTVRSRPL---SPVATPPPPPPPPPPPPPSSQ 436
Q P SP +P +P S+P LP+K +++ P + + PPPPP PPPPP+
Sbjct: 575 QEPAPVPSPPRAP--TPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA-- 630
Query: 437 RLPPPPPPPPPPLPEKKLITR 457
P PPP P + L+ R
Sbjct: 631 ---PSPPPAPATSSRRPLLLR 648
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/157 (22%), Positives = 73/157 (46%), Gaps = 16/157 (10%)
Query: 373 PNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPP 432
P + T V +P +P +S + P + +L + +Q ++++ L P A PPP P PPP
Sbjct: 709 PVVTTPVKAEVSPHGAPALS--NGPQTQAQLLQPLQALQTQ-LLPQALPPPQPQLQPPPS 765
Query: 433 PSSQRLPPPPPPPPPPLPEKKL--ITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPN 490
P Q++PP + L + + ++K+ + + Q++K + P
Sbjct: 766 P--QQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPG 823
Query: 491 SILKEIKNSLRSVQEK---KMEDSS------RPSTPQ 518
++E+ +++ + ++ + ED S RPS P+
Sbjct: 824 GQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPE 860
Score = 39.7 bits (91), Expect = 0.007
Identities = 32/88 (36%), Positives = 37/88 (42%), Gaps = 24/88 (27%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPP----PP---------PP 429
G+PSS + P P P+ RSR SP+A PPP PP PP
Sbjct: 1889 GSPSSLTHHIPTVGDPDFPAPPR-----RSRRPSPLAPRPPPSRWASPPLKTSPQLRVPP 1943
Query: 430 PPP------PSSQRLPPPPPPPPPPLPE 451
P P+S L PP P P PP PE
Sbjct: 1944 PTSVVTALTPTSGELAPPGPAPSPPPPE 1971
Score = 38.9 bits (89), Expect = 0.012
Identities = 44/180 (24%), Positives = 61/180 (33%), Gaps = 53/180 (29%)
Query: 384 TPSSSPYVSP--RHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLP-- 439
TP S+P P R S P + R P P A PPPP P PPP P +S R P
Sbjct: 588 TPPSTPVPLPEKRRSILREPTF-RWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLL 646
Query: 440 ---------------------PPP----------PPP---PPPLPEKKLITR-------N 458
PPP PPP P PE + + R
Sbjct: 647 LRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPR 706
Query: 459 IAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTPQ 518
A V+ A+ + G + + Q + L+++Q + + + P PQ
Sbjct: 707 FAPVVTTPVKAEVSPHGAPALSNGPQTQAQ-------LLQPLQALQTQLLPQALPPPQPQ 759
Score = 38.5 bits (88), Expect = 0.016
Identities = 34/120 (28%), Positives = 42/120 (35%), Gaps = 24/120 (20%)
Query: 376 RTKVWQRGTP-----SSSPYVSPRHSPWSSPKLPKKVQTV------RSRPLSPVATPPPP 424
RT W G P S P P S L K+ V P+ P PP
Sbjct: 2161 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL 2220
Query: 425 PPPPPPPPPSSQRLPPPP-------------PPPPPPLPEKKLITRNIAEVIKQQESAQR 471
PP P P+S LPP P PPPPP P +++ A +Q +R
Sbjct: 2221 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR 2280
Score = 36.6 bits (83), Expect = 0.061
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Query: 378 KVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLS---PVATPPPPPPPPPPPPPS 434
K+ G P P P P SP P T+ PL PV P PPPPPPP +
Sbjct: 2203 KMAGEGEPVPPPVKQPPLPPTISPTAPTS-WTLPPGPLLGVLPVVGVVRPAPPPPPPPLT 2261
Query: 435 SQRLPPPPPPPPPPLPEKKLIT 456
P PP + K++ T
Sbjct: 2262 LVLSSGPASPPRQAIRVKRVST 2283
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 11/81 (13%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATP-------PPPPPP----PPPP 431
G P SP V+P+ + + + V +R + TP PP PP P
Sbjct: 505 GPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLR 564
Query: 432 PPSSQRLPPPPPPPPPPLPEK 452
PP + P P P P P P +
Sbjct: 565 PPITTSPPVPQEPAPVPSPPR 585
Score = 29.6 bits (65), Expect = 7.4
Identities = 19/53 (35%), Positives = 21/53 (39%), Gaps = 5/53 (9%)
Query: 393 PRHSPWSSPKLPKKVQTVRSRPLSPVATPPPP-----PPPPPPPPPSSQRLPP 440
P S W+SP L Q P S V P PP P P PP + L P
Sbjct: 1923 PPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 59.7 bits (143), Expect = 7e-09
Identities = 28/67 (41%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRP--LSPVATPPPPPPPPPPPPPSSQRLPPPP 442
P +P +P P P P + S P ++P + PPPPP PPPPPP+ PPPP
Sbjct: 1457 PPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516
Query: 443 PPPPPPL 449
PP PL
Sbjct: 1517 PPAAAPL 1523
Score = 57.0 bits (136), Expect = 4e-08
Identities = 36/93 (38%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPP------PPPPPSSQR 437
TP P P P P LP V P SP P PPPPPP PPPPP++
Sbjct: 1466 TPQPQP---PPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP 1522
Query: 438 LPPPPPPPPPPLPE-KKLITRNIAEVIKQQESA 469
L PP P P PE +L + K+QE+A
Sbjct: 1523 LAAPPEEPAAPSPEDPELPDTRPLHLAKKQETA 1555
Score = 52.8 bits (125), Expect = 8e-07
Identities = 30/78 (38%), Positives = 36/78 (46%), Gaps = 15/78 (19%)
Query: 383 GTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPP----------PP 432
G PS++ +P P L +K +P PPPPPPPP P P
Sbjct: 1438 GLPSANSNGTPE-----PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPT 1492
Query: 433 PSSQRLPPPPPPPPPPLP 450
PSS PP PPPPPP +P
Sbjct: 1493 PSSPPPPPLPPPPPPAMP 1510
Score = 51.2 bits (121), Expect = 2e-06
Identities = 28/66 (42%), Positives = 28/66 (42%), Gaps = 16/66 (24%)
Query: 401 PKLPKKVQTVRSRPLSPVATPPPPPP--------PPPPPPPSSQRLPPPPP--------P 444
P LP P PPP PP PPPPPPP LP PPP P
Sbjct: 1437 PGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSP 1496
Query: 445 PPPPLP 450
PPPPLP
Sbjct: 1497 PPPPLP 1502
Score = 50.4 bits (119), Expect = 4e-06
Identities = 26/67 (38%), Positives = 27/67 (40%), Gaps = 1/67 (1%)
Query: 384 TPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPP 443
TP P P P P P+ PPP PPP P P Q PPPPP
Sbjct: 1418 TPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP-PPPPP 1476
Query: 444 PPPPPLP 450
PP P LP
Sbjct: 1477 PPQPALP 1483
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/70 (37%), Positives = 28/70 (40%), Gaps = 19/70 (27%)
Query: 404 PKKVQTVRSRPLSPVATPPPPPPPP-------------------PPPPPSSQRLPPPPPP 444
PK T PL+P A P PPP P PPP P P P PP
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP 1472
Query: 445 PPPPLPEKKL 454
PPPP P+ L
Sbjct: 1473 PPPPPPQPAL 1482
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 13/104 (12%)
Query: 397 PWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPP------PSSQRLPPPPPP----PP 446
PW P +P + P+S + PPP P PPP ++ PP P P
Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE 1725
Query: 447 PPLPEKKLITRNIAEVIKQQESAQRALQ--NGQKKKKGKKVKKQ 488
PP PEK + R + E K++E R + G++ G++ + +
Sbjct: 1726 PPAPEKPSLLRPV-EKEKEKEKVTRGERPLRGERATSGRQTRPE 1768
Score = 46.2 bits (108), Expect = 8e-05
Identities = 33/95 (34%), Positives = 40/95 (42%), Gaps = 17/95 (17%)
Query: 371 GGPNLRTKVWQRGTPSSSPYVSPR---HSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPP 427
GGP+L + P P + P H+P SP KV P + P PPPPP
Sbjct: 786 GGPDLPLVL-----PPPPPQLLPSVLSHAPSPSPSA-SKVGVHLLEPATRDGAPQPPPPP 839
Query: 428 PPPPPPSSQRLP--------PPPPPPPPPLPEKKL 454
PPPPPP +L P P P PE+ L
Sbjct: 840 PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESL 874
Score = 45.1 bits (105), Expect = 2e-04
Identities = 22/46 (47%), Positives = 27/46 (58%), Gaps = 9/46 (19%)
Query: 397 PWSSPKLPKKVQTVRSRPLSPV------ATPPPPPPPPPPPPPSSQ 436
P P+LP TV + PL + A PPPPPPPPPPP P+S+
Sbjct: 1012 PNKPPELPS---TVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASE 1054
Score = 36.2 bits (82), Expect = 0.079
Identities = 34/127 (26%), Positives = 43/127 (33%), Gaps = 38/127 (29%)
Query: 359 RLQEQKQ--QEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLS 416
RL+E+K+ + G + L T V G + + SP P + Q L
Sbjct: 724 RLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLL 783
Query: 417 PVATPPPPPPPPPPPPPSSQRL---------------------------------PPPPP 443
P P PPPPP Q L PPPPP
Sbjct: 784 EAGGPDLPLVLPPPPP---QLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP 840
Query: 444 PPPPPLP 450
PPPPP+P
Sbjct: 841 PPPPPMP 847
Score = 32.0 bits (71), Expect = 1.5
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 12/88 (13%)
Query: 388 SPYVSPRHSPWSSPKLPKKVQTVR---SRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444
SP+ P +P +P + R L P P PP P PP PPP
Sbjct: 184 SPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPD-------PPP 236
Query: 445 PPPPLPEK--KLITRNIAEVIKQQESAQ 470
PP LP + L + + A +Q S Q
Sbjct: 237 PPRHLPTQFNLLASSSAAAAAAEQSSPQ 264
Score = 31.6 bits (70), Expect = 2.0
Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 22/88 (25%)
Query: 376 RTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPV-------ATPPPPPPPP 428
+T ++ G P P PRH P L + S A P PPPP
Sbjct: 223 QTPPYRPGPPDPPP--PPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280
Query: 429 PPP-----------PPSSQRLPPPPPPP 445
P P S+Q PPPPPPP
Sbjct: 281 ALPRQDTVIKHYQRPASAQ--PPPPPPP 306
Score = 31.6 bits (70), Expect = 2.0
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 399 SSPKLPKKVQTVRSRPLSPVATPPPPPPPP--PPPPPSSQRLPPPPP 443
S + P Q + PLSP + PP P P PP++ +P PPP
Sbjct: 1291 SGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337
Score = 31.2 bits (69), Expect = 2.6
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 2/84 (2%)
Query: 402 KLPKKVQTVRSRP-LSPVATPP-PPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNI 459
+LP V + RSRP LSP+ PP P P P R P PP P + R +
Sbjct: 1120 RLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPL 1179
Query: 460 AEVIKQQESAQRALQNGQKKKKGK 483
++ +G KK +G+
Sbjct: 1180 EVPTTAGPASASTPTDGAKKPRGR 1203
Score = 30.8 bits (68), Expect = 3.3
Identities = 15/34 (44%), Positives = 17/34 (50%), Gaps = 5/34 (14%)
Query: 420 TPPPPPPPPPPPPPSSQRLPPPPP-----PPPPP 448
TPP PP PP ++ L P PP P PPP
Sbjct: 1304 TPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337
Score = 30.0 bits (66), Expect = 5.7
Identities = 15/40 (37%), Positives = 16/40 (40%)
Query: 411 RSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLP 450
R PL PP PP PP R P PP P +P
Sbjct: 1294 RHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVP 1333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,731,127
Number of Sequences: 37866
Number of extensions: 1929265
Number of successful extensions: 113861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2037
Number of HSP's successfully gapped in prelim test: 1283
Number of HSP's that attempted gapping in prelim test: 27346
Number of HSP's gapped (non-prelim): 36086
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.