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Search of human proteins with 110347451
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347451 platelet/endothelial cell adhesion molecule [Homo
sapiens]
(738 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347451 platelet/endothelial cell adhesion molecule [Homo s... 1463 0.0
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens] 111 3e-24
gi|157694526 Fc receptor-like 5 [Homo sapiens] 109 8e-24
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens] 83 8e-16
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 78 3e-14
gi|110349719 titin isoform N2-A [Homo sapiens] 69 2e-11
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 62 2e-09
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 62 2e-09
gi|118572606 hemicentin 1 [Homo sapiens] 61 4e-09
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 57 5e-08
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 57 8e-08
gi|18201909 vascular cell adhesion molecule 1 isoform b precurso... 56 1e-07
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 56 1e-07
gi|146229333 hypothetical protein LOC284021 [Homo sapiens] 56 1e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 55 2e-07
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 55 2e-07
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 55 2e-07
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 55 2e-07
gi|157057547 Fc receptor-like 6 [Homo sapiens] 55 3e-07
gi|71274107 melanoma cell adhesion molecule [Homo sapiens] 53 1e-06
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 52 2e-06
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 52 2e-06
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 52 2e-06
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 52 2e-06
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 51 3e-06
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 51 3e-06
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 51 4e-06
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens] 50 6e-06
gi|11225258 myelin associated glycoprotein isoform a precursor [... 50 6e-06
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens] 50 8e-06
>gi|110347451 platelet/endothelial cell adhesion molecule [Homo
sapiens]
Length = 738
Score = 1463 bits (3787), Expect = 0.0
Identities = 738/738 (100%), Positives = 738/738 (100%)
Query: 1 MQPRWAQGATMWLGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFAD 60
MQPRWAQGATMWLGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFAD
Sbjct: 1 MQPRWAQGATMWLGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFAD 60
Query: 61 VSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTT 120
VSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTT
Sbjct: 61 VSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTT 120
Query: 121 AEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKRE 180
AEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKRE
Sbjct: 121 AEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKRE 180
Query: 181 KNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHI 240
KNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHI
Sbjct: 181 KNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHI 240
Query: 241 SPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSG 300
SPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSG
Sbjct: 241 SPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSG 300
Query: 301 NYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQ 360
NYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQ
Sbjct: 301 NYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQ 360
Query: 361 KEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFE 420
KEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFE
Sbjct: 361 KEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFE 420
Query: 421 VIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADN 480
VIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADN
Sbjct: 421 VIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADN 480
Query: 481 CHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREK 540
CHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREK
Sbjct: 481 CHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREK 540
Query: 541 EGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWK 600
EGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWK
Sbjct: 541 EGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWK 600
Query: 601 KGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEAN 660
KGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEAN
Sbjct: 601 KGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEAN 660
Query: 661 SHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAV 720
SHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAV
Sbjct: 661 SHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAV 720
Query: 721 PDAVESRYSRTEGSLDGT 738
PDAVESRYSRTEGSLDGT
Sbjct: 721 PDAVESRYSRTEGSLDGT 738
>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
Length = 734
Score = 111 bits (277), Expect = 3e-24
Identities = 168/769 (21%), Positives = 301/769 (39%), Gaps = 129/769 (16%)
Query: 15 VLLTLLLCSSLEGQENSFTINSVDMKSLPDW-TVQNGKNLTLQCFADVSTTSHVKPQHQM 73
+LL LLL G+E S + P W T G+ + L C S+ SH Q
Sbjct: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALIC----SSISHSLAQGDT 56
Query: 74 LFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSP 133
+Y D+ L +K + ++I + G Y+C ++ + VE P
Sbjct: 57 YWYHDEKLL----KIKHDK------IQITEPGNYQCKT-----RGSSLSDAVHVEFSPDW 101
Query: 134 RVTLDKKEAIQGGIVRVNCSVPEEK-------------APIHFTIEKLELNEKMVKLKRE 180
+ +G V + C + K P + +EK+ +N +
Sbjct: 102 LILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKY 161
Query: 181 KNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHI 240
+ + F IL+ V ++K + V E F P
Sbjct: 162 HCTAYRKFYILDIEV-------------------------TSKPLNIQVQELFLHPVLRA 196
Query: 241 SPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQ----KDKAIVAHNRHGNKAVYSVMAMV 296
S + I EG+ + + C T L+ + P++ +Q +D + + +
Sbjct: 197 SSSTPI-EGSPMTLTCE---TQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWT 252
Query: 297 EHSGNYTCKVESSRIS----------KVSSIVVNITELFSKPELESSFTHLDQGERLNLS 346
E SG+Y C+VE+ S +V + V+ L E+ + L +GE + L
Sbjct: 253 EDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNL----EIRPTGGQLIEGENMVLI 308
Query: 347 CSIP-GAPPANFTIQKEDTIVSQTQDFTK---------IASKSDSGTYICTAGIDKVVKK 396
CS+ G+ F+ KE + S + + +SD+G Y C A
Sbjct: 309 CSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPIL 368
Query: 397 SNTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENST 455
S +++ V +S P +++ A + + G +E+ CES+ G+ PI Y+ L NS+
Sbjct: 369 STWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSS 428
Query: 456 KNSNDPAVFKDNPTED--VEYQCVADN----CHSHAKMLSEVLRVKVIAPVDEVQISILS 509
S A F + T + Y C ADN HSH + ++V PV +++ +
Sbjct: 429 APSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHG------VSLRVTVPVSRPVLTLRA 482
Query: 510 -SKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEG 568
G+ + L C GS PI Y FY E + S +F + E G
Sbjct: 483 PGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASF--NLSLTTEHSG 540
Query: 569 EYYCTAFNRANHASSVPRSKILTVRVI-LAPWKKGLIAVVIIGVIIALLIIAAKCYFLRK 627
Y C A++ SK++T+ V + + GL A I G+++++L++AA L
Sbjct: 541 NYSC----EADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHY 596
Query: 628 AKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYG-----HNDDVRNHAMKPINDNKE 682
A+A++ P +S A + + + +P+ S H+ + ++P+ N
Sbjct: 597 ARARRKPGGLS--ATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVN 654
Query: 683 PLNSDVQYTEV---------QVSSAESHKDLGKKDTETVYSEVRKAVPD 722
P +S+ Y+++ + H++ ++ +YSE++K PD
Sbjct: 655 PGDSNPIYSQIWSIQHTKENSANCPMMHQE--HEELTVLYSELKKTHPD 701
>gi|157694526 Fc receptor-like 5 [Homo sapiens]
Length = 977
Score = 109 bits (273), Expect = 8e-24
Identities = 161/703 (22%), Positives = 278/703 (39%), Gaps = 82/703 (11%)
Query: 58 FADVSTTSHVKPQHQML-----FYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVI 112
F T H + Q L FY + V + S + + +SG Y CT
Sbjct: 299 FEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTAD 358
Query: 113 VNNKEKTTAEYQLLVE-GVPSPRVTLDKKEAI--QGGIVRVNCSVPEEKAPIHFTIEKLE 169
K + L V V P + L E + +G V ++C PI +
Sbjct: 359 NGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFH--- 415
Query: 170 LNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTV 229
+E +R NS + E ++ C A +G Q S++ ++V
Sbjct: 416 -HEGAALERRSANSAGGVAISFSLTAEHSG---NYYCTAD--NGFGPQRSKAVS---LSV 466
Query: 230 TESFSTPKFHISPT-GMIMEGAQLHIKCTIQVTHLAQEFPEIIIQ---KDKAIVAHNRHG 285
T S P +S + EGA + + C +Q + P+I+ Q +D + + +
Sbjct: 467 TVPVSHPVLTLSSAEALTFEGATVTLHCEVQ-----RGSPQILYQFYHEDMPLWSSSTPS 521
Query: 286 NKAVYSVMAMVE-HSGNYTCKVESSRISKVSSIV-VNITELFSKPELESSFTHLDQ--GE 341
V ++ E HSGNY C ++ + S +V + +T S+P L G+
Sbjct: 522 VGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGD 581
Query: 342 RLNLSCSIP-GAPPANFTIQKEDTIVSQTQ-------DFTKIASKSDSGTYICTAGIDKV 393
L L C P G+PP + ED + + F + SG Y C A V
Sbjct: 582 LLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLV 641
Query: 394 VKKSNTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLE 452
+ S+T+ + V +S+P +++ A + + + G +E+ CE++ G+ PI Y L
Sbjct: 642 AQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLG 701
Query: 453 NSTKNSNDPAVFKDNPTEDVE--YQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSS 510
+ S A F + T + Y C ADN + SE++ +KV PV +++ +
Sbjct: 702 KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQR--SEMVTLKVAVPVSRPVLTLRAP 759
Query: 511 KVVESGEDIV-LQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGE 569
+ D++ L C GS I Y+F+ E S + E G
Sbjct: 760 GTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPSGGAS---LNLSLTAEHSGN 816
Query: 570 YYCTAFNRANHASSVPRSKILTVRVI-LAPWKKGLIAVVIIGVIIALLIIAA-----KCY 623
Y C A++ RS+ +T+ + L + G A + G ++++ +AA C+
Sbjct: 817 YSC----EADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIAGLAAGALLLYCW 872
Query: 624 FLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVRNHAMKPINDNKEP 683
RKA K S PA +S++++ + N+ A ++P+ N P
Sbjct: 873 LSRKAGRK----PASDPARSPSDSDSQEPTYHNVPAWEE-----------LQPVYTNANP 917
Query: 684 LNSDVQYTEVQV-------SSAESHKDLGKKDTETVYSEVRKA 719
+V Y+EV++ + A + L K + +YSEV+ A
Sbjct: 918 RGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVA 960
Score = 96.3 bits (238), Expect = 9e-20
Identities = 132/575 (22%), Positives = 234/575 (40%), Gaps = 61/575 (10%)
Query: 49 NGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYK 108
+G +TL C +S P F D L S + ++ I + DSG Y
Sbjct: 203 SGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSL---SPNFQITAMWSKDSGFYW 259
Query: 109 CTV------IVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAI--QGGIVRVNCSVPEE--K 158
C ++++ ++ + Q+ P +TL ++A+ +G V ++C E+ +
Sbjct: 260 CKAATMPYSVISDSPRSWIQVQIPAS---HPVLTLSPEKALNFEGTKVTLHCETQEDSLR 316
Query: 159 APIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQT 218
F E + L K V+ +R + + F + ++ ++ C A G
Sbjct: 317 TLYRFYHEGVPLRHKSVRCERGAS--------ISFSLTTENSG-NYYCTADNGLG----- 362
Query: 219 SESTKSELVTVTESFSTPKFHIS-PTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKA 277
++ +K+ ++VT S P ++S P +I EGA++ + C Q L P + +
Sbjct: 363 AKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSL----PILYQFHHEG 418
Query: 278 IVAHNRHGNKA---VYSVMAMVEHSGNYTCKVESS---RISKVSSIVVNITELFSKPELE 331
R N A S EHSGNY C ++ + SK S+ V + L
Sbjct: 419 AALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLS 478
Query: 332 SSFTHLDQGERLNLSCSIP-GAPPANFTIQKEDTIV--SQTQDFTKIA-----SKSDSGT 383
S+ +G + L C + G+P + ED + S T +++ ++ SG
Sbjct: 479 SAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGN 538
Query: 384 YICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISY 442
Y CTA ++S V + V +S+P ++ + + + G +E+ CE+ G+ PI Y
Sbjct: 539 YYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILY 598
Query: 443 QLLKTSKVLENSTKNSNDPAVFKDNPTEDVE--YQCVADNCHSHAKMLSEVLRVKVIAPV 500
L +S+ S A F + T + Y C A+N S+ + + VI PV
Sbjct: 599 WFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANN--GLVAQHSDTISLSVIVPV 656
Query: 501 DEVQISILSSKV-VESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTK 559
++ + + G+ + L C GS PI Y FY E S +F
Sbjct: 657 SRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASF--N 714
Query: 560 QKASKEQEGEYYCTAFNRANHASSVPRSKILTVRV 594
+ E G Y C A++ RS+++T++V
Sbjct: 715 LSLTTEHSGIYSC----EADNGLEAQRSEMVTLKV 745
Score = 89.4 bits (220), Expect = 1e-17
Identities = 138/580 (23%), Positives = 230/580 (39%), Gaps = 68/580 (11%)
Query: 46 TVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSG 105
+V G ++ L+C A T + ++ D+VL + + + IP + D+G
Sbjct: 112 SVFEGDSVVLRCRAKAEVTLN-----NTIYKNDNVLAF----LNKRTDFHIPHACLKDNG 162
Query: 106 TYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTI 165
Y+CT Y+ V S V + +E ++R + P P+ T
Sbjct: 163 AYRCT-----------GYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTC 211
Query: 166 E-KLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLS--------FRCQARIISGIHM 216
E +L L V L R + RD + L + + ++ + + C+A + +
Sbjct: 212 ETQLSLERSDVPL-RFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMP--YS 268
Query: 217 QTSESTKSELVTVTESFSTPKFHISP-TGMIMEGAQLHIKCTIQ---VTHLAQEFPEIII 272
S+S +S + V S P +SP + EG ++ + C Q + L + + E +
Sbjct: 269 VISDSPRS-WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVP 327
Query: 273 QKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIV-VNITELFSKPELE 331
+ K++ R A S E+SGNY C ++ +K S V +++T S P L
Sbjct: 328 LRHKSV----RCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLN 383
Query: 332 SSFTH--LDQGERLNLSCSIP-GAPPANFTIQKEDTIVSQTQ-------DFTKIASKSDS 381
S + +G ++ L C G+ P + E + + + + S
Sbjct: 384 LSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHS 443
Query: 382 GTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISY-DAQFEVIKGQTIEVRCESISGTLPI 440
G Y CTA ++S V + V +S P ++ A+ +G T+ + CE G+ I
Sbjct: 444 GNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQI 503
Query: 441 SYQLLKTSKVLENSTKNSNDPAVFKDNPTE--DVEYQCVADNCHSHAKMLSEVLRVKVIA 498
YQ L +S+ S F + TE Y C ADN SEV+ + V
Sbjct: 504 LYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADN--GFGPQRSEVVSLFVTV 561
Query: 499 PVDEVQISILSSKVVES----GEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQ 554
PV IL+ +V + G+ + L C GS PI Y FY E S
Sbjct: 562 PVSR---PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEA 618
Query: 555 AFWTKQKASKEQEGEYYCTAFNR--ANHASSVPRSKILTV 592
+F + E G Y C A N A H+ ++ S I+ V
Sbjct: 619 SF--NLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPV 656
Score = 38.1 bits (87), Expect = 0.030
Identities = 59/265 (22%), Positives = 106/265 (40%), Gaps = 49/265 (18%)
Query: 330 LESSFTHLDQGERLNLSC------SIPGAPPANFTIQKEDTIVSQTQDFTKIASKSDSGT 383
L+ +T + QGER+ L+C S + + KE I+ +T D I +SG
Sbjct: 27 LQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKE--ILRETPD--NILEVQESGE 82
Query: 384 YICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQ 443
Y C A + + + V S + A V +G ++ +RC + + ++
Sbjct: 83 YRCQA-------QGSPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA-KAEVTLNNT 134
Query: 444 LLKTSKVLENSTKNSN---DPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPV 500
+ K VL K ++ A KDN Y+C S + S ++++V P
Sbjct: 135 IYKNDNVLAFLNKRTDFHIPHACLKDNGA----YRCTGYK-ESCCPVSSNTVKIQVQEPF 189
Query: 501 DEVQISILSSKVVESGEDIVLQC----AVNEGSGPITYKFYREKEG-------KPFYQMT 549
+ S + + SG + L C ++ P+ ++F+R+ + P +Q+T
Sbjct: 190 TRPVLRASSFQPI-SGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQIT 248
Query: 550 SNATQAFWTKQKASKEQEGEYYCTA 574
A W+K G Y+C A
Sbjct: 249 -----AMWSK------DSGFYWCKA 262
>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
Length = 515
Score = 83.2 bits (204), Expect = 8e-16
Identities = 91/372 (24%), Positives = 155/372 (41%), Gaps = 51/372 (13%)
Query: 376 ASKSDSGTYICTA-GIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESI 434
AS +++G Y C G + V +SN I + E+ P + + +G ++ + CE+
Sbjct: 157 ASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKA-TDSQPTEGNSVNLSCETQ 215
Query: 435 ----SGTLPISYQLLKTSKVLENSTKNSND---PAVFKDNPTEDVEYQCVAD----NCHS 483
P+ + + +V+ + + P V+++N Y C A+ N H
Sbjct: 216 LPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGS---YWCGAETVRGNIHK 272
Query: 484 HAKMLS-EVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEG 542
H+ L V R+ V + E Q S + VE GE +VL C+V EG+G T+ ++RE
Sbjct: 273 HSPSLQIHVQRIPVSGVLLETQPS--GGQAVE-GEMLVLVCSVAEGTGDTTFSWHREDMQ 329
Query: 543 KPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKK- 601
+ + T + +A + G YYCTA N S+ +L V V P +
Sbjct: 330 ESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSM----VLNVTVRETPGNRD 385
Query: 602 GLIAVVIIGVIIALLIIAA----KCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNM 657
GL+A G +++ L++A C+ RK+ + E P P ++ + +
Sbjct: 386 GLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQV 445
Query: 658 EANSHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKD-------LGKKDTE 710
E S Y + P D+ Y+E+Q + ++ L KD
Sbjct: 446 ELQSLY---------------VDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVS 490
Query: 711 TVYSEVRKAVPD 722
VYSEV+ PD
Sbjct: 491 VVYSEVKTQHPD 502
Score = 42.4 bits (98), Expect = 0.002
Identities = 54/227 (23%), Positives = 101/227 (44%), Gaps = 30/227 (13%)
Query: 294 AMVEHSGNYTC--KVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPG 351
A ++GNY C + + + + + ++ I ELF PEL+++ + +G +NLSC
Sbjct: 157 ASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQL 216
Query: 352 AP-----PANFTIQKE-DTIVSQTQDFTKI----ASKSDSGTYICTAGI--DKVVKKSNT 399
P P +F ++ + I+S + ++ + +SG+Y C A + K S +
Sbjct: 217 PPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPS 276
Query: 400 VQIVVCEMLSQPRISYDAQ---FEVIKGQTIEVRCESISGT--LPISYQLLKTSKVLENS 454
+QI V + + + + Q + ++G+ + + C GT S+ + L
Sbjct: 277 LQIHV-QRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRK 335
Query: 455 TKNS-----NDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKV 496
T+ S PA+ + + Y C ADN S+ + S VL V V
Sbjct: 336 TQRSLRAELELPAIRQSHAG---GYYCTADN--SYGPVQSMVLNVTV 377
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 77.8 bits (190), Expect = 3e-14
Identities = 118/514 (22%), Positives = 206/514 (40%), Gaps = 73/514 (14%)
Query: 246 IMEGAQLHIKCTIQVTHLAQEFPEIIIQKD-KAIVAHNRHGNKAVYSVMAMVEHSGNYTC 304
+ EG + +KC + Q+ + KD K + + + + S A++ SGNY C
Sbjct: 28 VFEGDSIVLKCQGEQNWKIQK---MAYHKDNKELSVFKKFSDFLIQS--AVLSDSGNYFC 82
Query: 305 KVESSRI--SKVSSIV-VNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPA-----N 356
+ K S+IV + + ELF +P L +S +G ++L C +P
Sbjct: 83 STKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLDVQLQ 142
Query: 357 FTIQKEDTIV-----SQTQDFTKIASKSDSGTYICTAG-IDKVVKKSNTVQIVVCEMLSQ 410
F +E+ ++ S + D+G+Y C A + ++K + + + +
Sbjct: 143 FCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPI 202
Query: 411 PRISYDAQF---EVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDN 467
+S + + +V +GQ + + C GT +++ + + K + +
Sbjct: 203 SNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEI 262
Query: 468 P----TEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIV-LQ 522
P ++ +Y C ADN H + S+V+ + V PV +++ S + D++ L
Sbjct: 263 PAVKESDAGKYYCRADN--GHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELH 320
Query: 523 CAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFN--RANH 580
C GS PI Y+FY E S +F + E G Y C A N A
Sbjct: 321 CEALRGSPPILYQFYHEDVTLGNSSAPSGGGASF--NLSLTAEHSGNYSCEANNGLGAQC 378
Query: 581 ASSVP---------RSKILTVRVILAPWKKGLIAVV-IIGVIIALLIIAAKCYFLRKAKA 630
+ +VP R ++T V+ W GL V+ GV ALL+ A ++ A
Sbjct: 379 SEAVPVSISGPDGYRRDLMTAGVL---W--GLFGVLGFTGV--ALLLYALFHKISGESSA 431
Query: 631 KQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVRNHAMKPINDNKEPLNSDVQY 690
P SRP N S P + ++P+ N ++ DV Y
Sbjct: 432 TNEPRGASRP-----NPQEFTYSSPTPDMEE------------LQPVYVNVGSVDVDVVY 474
Query: 691 TEV-----QVSSAESHKDLGKKDTETVYSEVRKA 719
++V SSA L KD++ +YS V+K+
Sbjct: 475 SQVWSMQQPESSANIRTLLENKDSQVIYSSVKKS 508
Score = 59.3 bits (142), Expect = 1e-08
Identities = 74/300 (24%), Positives = 124/300 (41%), Gaps = 37/300 (12%)
Query: 227 VTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQ----KDKAIVAHN 282
+ V E F P S I EG + +KC T L+ + ++ +Q ++ ++
Sbjct: 100 IKVQELFQRPVLTASSFQPI-EGGPVSLKCE---TRLSPQRLDVQLQFCFFRENQVLGSG 155
Query: 283 RHGNKAVYSVMAMVEHSGNYTCKVES--SRISK--------VSSIVVNITELFSKPELES 332
+ + E +G+Y CK E+ RI K V I ++ L E+ +
Sbjct: 156 WSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSL----EIRA 211
Query: 333 SFTHLDQGERLNLSCSIPGAPP-ANFTIQKEDTIVSQTQDFTKIAS---------KSDSG 382
+ +G++L L CS+ G F+ +E T S + + S +SD+G
Sbjct: 212 PGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAG 271
Query: 383 TYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQ-FEVIKGQTIEVRCESISGTLPIS 441
Y C A V +S V I V +S+P ++ + + G +E+ CE++ G+ PI
Sbjct: 272 KYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPIL 331
Query: 442 YQLLKTSKVLENSTKNSNDPAVFKDNPTED--VEYQCVADNCHSHAKMLSEVLRVKVIAP 499
YQ L NS+ S A F + T + Y C A+N SE + V + P
Sbjct: 332 YQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANN--GLGAQCSEAVPVSISGP 389
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 68.6 bits (166), Expect = 2e-11
Identities = 85/323 (26%), Positives = 133/323 (41%), Gaps = 35/323 (10%)
Query: 296 VEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQ--GERLNLSCSIPGAP 353
+ SG YTCK E+S + S V I E P ++Q G + L+C + G+
Sbjct: 6143 INDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSA 6202
Query: 354 PANFTIQKEDTIVS-----QTQDFTKIASK-------SDSGTYICTAGIDKVVKKSNTVQ 401
P ++ ++ QT +A+ S SG Y C+A + + S++ +
Sbjct: 6203 PIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSAS-NPLGTASSSAR 6261
Query: 402 IVVCEMLSQPRISYD-AQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENS-----T 455
+ E P +VI G++ + C ++G P+ K +K + T
Sbjct: 6262 LTAREPKKSPFFDIKPVSIDVIAGESADFECH-VTGAQPMRITWSKDNKEIRPGGNYTIT 6320
Query: 456 KNSNDP--AVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVV 513
N P + K + +Y C A N M S L VK P V+ + +SKV
Sbjct: 6321 CVGNTPHLRILKVGKGDSGQYTCQATN-DVGKDMCSAQLSVK--EPPKFVK-KLEASKVA 6376
Query: 514 ESGEDIVLQCAVNEGSGPITYKFYR---EKEGKPFYQMTSNATQAFWTKQKASKEQEGEY 570
+ GE I L+C ++ GS I ++R E Y M+ + A T +AS E G+Y
Sbjct: 6377 KQGESIQLECKIS-GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDY 6435
Query: 571 YCTAFNRANHASSVPRSKILTVR 593
C A N AS S LTV+
Sbjct: 6436 ICEAHNGVGDASC---STALTVK 6455
Score = 60.1 bits (144), Expect = 7e-09
Identities = 117/551 (21%), Positives = 213/551 (38%), Gaps = 83/551 (15%)
Query: 83 YNISSMKSTESYFIPEVRIYDSGTYKC--TVIVNNKEKTTAEYQLLVEGVPSPRVTLDKK 140
Y I+ ++ T S I V + D+G + C T V +K+ + A L+V+ PS K
Sbjct: 4159 YRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGA---LIVQEPPSFVTKPGSK 4215
Query: 141 EAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDR 200
+ + G V C + TI + N+++V +++ LE + +
Sbjct: 4216 DVLPGSAV---CLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSD 4272
Query: 201 VLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQV 260
++ C+ ++G ++ E T E + P+ ++ +G + C +
Sbjct: 4273 SGTYTCKVSNVAGGVECSANLFVKEPATFVEK-------LEPSQLLKKGDATQLACKVTG 4325
Query: 261 THLAQEFPEIII---QKDKAIVAHNRHGNKAVYSVMAM------VEHSGNYTCKVESSRI 311
T P I I D+ I ++H V S + +E SG Y C+ ++
Sbjct: 4326 T------PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 4379
Query: 312 SKVSSIVVNITELFSKPELESSFTHLDQGERLN--LSCSIPGAPPANFTIQKEDTIVSQT 369
S S +V + E P F ++ + + L + G PP T K++TI+
Sbjct: 4380 SDHCSSIVIVKE---SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSG 4436
Query: 370 QDFTKIAS------------KSDSGTYICTAGIDKVVKKSNTVQIVVCE---MLSQPR-- 412
+ + +D+G Y C + +N V +C L +P
Sbjct: 4437 RKYKTFIQDHLVSLQILKFVAADAGEYQC--------RVTNEVGSSICSARVTLREPPSF 4488
Query: 413 ISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPT--- 469
I ++G T + ++ G+LPI+ LK S + T++ N F++N
Sbjct: 4489 IKKIESTSSLRGGTAAFQA-TLKGSLPITVTWLKDS---DEITEDDNIRMTFENNVASLY 4544
Query: 470 -------EDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQ 522
D +Y C A N + + S +L VK A + E +SI V G+ LQ
Sbjct: 4545 LSGIEVKHDGKYVCQAKN-DAGIQRCSALLSVKEPATITEEAVSI----DVTQGDPATLQ 4599
Query: 523 CAVNEGSGPITYKFYREKEGKPF---YQMTSNATQAFWTKQKASKEQEGEYYCTAFNRAN 579
+ G+ IT K++++ + Y+++ T + K+ GEY N
Sbjct: 4600 VKFS-GTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVG 4658
Query: 580 HASSVPRSKIL 590
+S R +L
Sbjct: 4659 RSSCKARINVL 4669
Score = 59.3 bits (142), Expect = 1e-08
Identities = 81/320 (25%), Positives = 133/320 (41%), Gaps = 35/320 (10%)
Query: 296 VEHSGNYTCKVE--SSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP 353
VE +G Y C +E S + S + I++ F K +LE + G+ +L C + G P
Sbjct: 7932 VEDAGQYNCYIENASGKDSCSAQILILEPPYFVK-QLEP--VKVSVGDSASLQCQLAGTP 7988
Query: 354 PANFTIQKEDTIVSQTQDF---------TKIASK---SDSGTYICTAGIDKVVKKSNTVQ 401
+ K DT + T + T + ++ +DSG YIC A + V + S +
Sbjct: 7989 EIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAE-NSVGEVSASTF 8047
Query: 402 IVVCEMLSQPRISYDAQ-FEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK---- 456
+ V E P S + + G + C +ISG+ PIS K K L++S
Sbjct: 8048 LTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSPNVQTS 8106
Query: 457 ---NSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVK-VIAPVDEVQISILSSKV 512
N+ +FK + + +Y C A N A + ++ + P +++++ + + V
Sbjct: 8107 FLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVV 8166
Query: 513 VESGEDIVLQCAVNEGSGPITY---KFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGE 569
ES + +C V G+ PI K RE YQ++ A T K K G+
Sbjct: 8167 GESAD---FECHVT-GTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQ 8222
Query: 570 YYCTAFNRANHASSVPRSKI 589
Y C A N S + I
Sbjct: 8223 YTCYAVNEVGKDSCTAQLNI 8242
Score = 55.8 bits (133), Expect = 1e-07
Identities = 90/388 (23%), Positives = 157/388 (40%), Gaps = 61/388 (15%)
Query: 227 VTVTESFSTPKFHISPTGMI-MEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHG 285
+TVTE++ P F P + G CT+ T + E I QKD A ++ + +
Sbjct: 3543 LTVTEAYP-PTFLSRPKSLTTFVGKAAKFICTVTGTPVI----ETIWQKDGAALSPSPNW 3597
Query: 286 ------NKAVYSVMAM-VEHSGNYTCKVES---SRISKVSSIVVN----ITELFSKPELE 331
NK + + + ++ G Y+CK + + I + I+++ I EL
Sbjct: 3598 RISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAI 3657
Query: 332 SSFTHL----DQGERLNLSCSIPGA---PPANFTIQKEDTIVSQTQDFTKIASKSDSGTY 384
+ HL D+ ++ ++ S G P ++ I ED I + K+ DSGTY
Sbjct: 3658 NKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKL---KDSGTY 3714
Query: 385 ICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQL 444
+CTA ++ S + + V E S + D + ++ G++ + C+ + G+ I
Sbjct: 3715 VCTAS-NEAGSSSCSATVTVREPPSFVK-KVDPSYLMLPGESARLHCK-LKGSPVIQVTW 3771
Query: 445 LKTSKVLENSTK------NSNDPAVFKDNPTEDV-EYQCVA------DNCHSHAKMLSEV 491
K +K L S NS D ED Y C A D+C + +
Sbjct: 3772 FKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 3831
Query: 492 LRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKE---GKPFYQM 548
+K + P D V+ G + +LQC V+ G+GP ++++K+ Y++
Sbjct: 3832 SFIKTLEPADIVR-----------GTNALLQCEVS-GTGPFEISWFKDKKQIRSSKKYRL 3879
Query: 549 TSNATQAFWTKQKASKEQEGEYYCTAFN 576
S + + GEY C N
Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVAN 3907
Score = 53.9 bits (128), Expect = 5e-07
Identities = 143/589 (24%), Positives = 220/589 (37%), Gaps = 91/589 (15%)
Query: 47 VQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLF-----YNISSMKSTESYFIPEVRI 101
V G TL+C T P+ ++KD Y IS I V
Sbjct: 7597 VTTGDTCTLEC------TVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAP 7650
Query: 102 YDSGTYKCTVIVN-NKEKTTAEYQLLVEGVPSPRVTLDKKEA--IQGGIVRVNCSV---- 154
DSG Y V K+ TA Q+ VP P T KE + G V + C V
Sbjct: 7651 SDSGVYSFEVQNPVGKDSCTASLQVSDRTVP-PSFTRKLKETNGLSGSSVVMECKVYGSP 7709
Query: 155 PEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGI 214
P + H E NE K + D + +EE D + C A ++G
Sbjct: 7710 PISVSWFH------EGNEISSGRKYQTTLTDNTCALTVNMLEESDSG-DYTCIATNMAG- 7761
Query: 215 HMQTSESTKSELVTVTESFSTPKFHISPTGM-IMEGAQLHIKCTIQVTHLAQEFPEIIIQ 273
S+ + L TV E P F P M ++ G + ++ T F +
Sbjct: 7762 ----SDECSAPL-TVREP---PSFVQKPDPMDVLTGTNVTFTSIVKGT---PPFSVSWFK 7810
Query: 274 KDKAIVAHNRHGNKAVYSVMAM------VEHSGNYTCKV--ESSRISKVSSIVVNITELF 325
+V +R SV + SG YTC V E+ + S + + + F
Sbjct: 7811 GSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKF 7870
Query: 326 SKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQD----------FTKI 375
K + S +++G+ L L + G PP + T +K V+ +Q +I
Sbjct: 7871 VKRLNDYS---IEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEI 7927
Query: 376 ASKS--DSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIK---GQTIEVR 430
S + D+G Y C + K S + QI++ E + Q E +K G + ++
Sbjct: 7928 PSSTVEDAGQYNCYIE-NASGKDSCSAQILILEPPY-----FVKQLEPVKVSVGDSASLQ 7981
Query: 431 CESISGTLPISYQLLKTSKVLENST------KNSNDPAVFKDNPTEDV-EYQCVADNCHS 483
C+ ++GT I K L +T +N+ VF D EY C A+N
Sbjct: 7982 CQ-LAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVG 8040
Query: 484 HAKMLSEV-LRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEG 542
+ + ++ + + P Q+ + V G +V CA++ GS PI+ +Y K+G
Sbjct: 8041 EVSASTFLTVQEQKLPPSFSRQLRDVQETV---GLPVVFDCAIS-GSEPISVSWY--KDG 8094
Query: 543 KPFYQMTSNATQ-----AFWTKQKASKEQEGEYYCTAFNRANHASSVPR 586
KP + T A K + G+Y CTA N ASS R
Sbjct: 8095 KPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSAR 8143
Score = 50.4 bits (119), Expect = 6e-06
Identities = 72/337 (21%), Positives = 132/337 (39%), Gaps = 46/337 (13%)
Query: 286 NKAVYSVMAMVEHS--GNYTCKVESSRISKVSSIVVNITELFSKPELESSF--THLDQGE 341
N V+ V+HS G Y+CK ++S + SS V+ I P H G
Sbjct: 7072 NNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGF 7131
Query: 342 RLNLSCSIPGAPPANFTIQKEDTIVS-----QTQDFTKIAS-------KSDSGTYICTAG 389
+ C I G+ P + K+ ++ QT +A+ +S G Y C+A
Sbjct: 7132 PVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSAS 7191
Query: 390 IDKVVKKSNTVQIVVCEMLSQPRISYD-AQFEVIKGQTIEVRCESISGTLPISYQLLKTS 448
+ + S++ ++++ E P ++ G++ +C ++GT PI K +
Sbjct: 7192 -NPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCH-VTGTAPIKITWAKDN 7249
Query: 449 KVLENS-------TKNSNDPAVFKDNPTEDVEYQCVA------DNCHSHAKMLSEVLRVK 495
+ + +N+ V K + +Y C A D+C + + +K
Sbjct: 7250 REIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIK 7309
Query: 496 VIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREK---EGKPFYQMTSNA 552
+ P S++V+ E +C + GS I +Y+++ + ++M+
Sbjct: 7310 KLEP----------SRIVKQDEFTRYECKIG-GSPEIKVLWYKDETEIQESSKFRMSFVD 7358
Query: 553 TQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKI 589
+ A S E G+Y C A N A ASS K+
Sbjct: 7359 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 7395
Score = 47.4 bits (111), Expect = 5e-05
Identities = 67/306 (21%), Positives = 118/306 (38%), Gaps = 39/306 (12%)
Query: 299 SGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQ--GERLNLSCSIPGAPPAN 356
+G Y+C++E+ V +V+ E P + L+ G+ ++L C + G P
Sbjct: 6053 AGQYSCEIENEAGRDVCGALVSTLE---PPYFVTELEPLEAAVGDSVSLQCQVAGTPEIT 6109
Query: 357 FTIQKEDTIVSQTQDF---------TKIASK---SDSGTYICTAGIDKVVKKSNTVQIVV 404
+ K DT + T ++ T + +K +DSG Y C A S TV +
Sbjct: 6110 VSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQ 6169
Query: 405 CEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISY------QLLKTSKVLENS-TKN 457
L E G + + C ++G+ PI LL+ + L+ S N
Sbjct: 6170 ERQLPPSFARQLKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDGVLLRDDENLQTSFVDN 6228
Query: 458 SNDPAVFKDNPTEDVEYQCVADN----CHSHAKMLSEVLRVKVIAPVDEVQISILSSKVV 513
+ + + + +Y C A N S A++ + + + V I ++
Sbjct: 6229 VATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVI----- 6283
Query: 514 ESGEDIVLQCAVNEGSGPITYKFYRE-KEGKP--FYQMTSNATQAFWTKQKASKEQEGEY 570
+GE +C V G+ P+ + ++ KE +P Y +T K K G+Y
Sbjct: 6284 -AGESADFECHVT-GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQY 6341
Query: 571 YCTAFN 576
C A N
Sbjct: 6342 TCQATN 6347
Score = 46.2 bits (108), Expect = 1e-04
Identities = 81/417 (19%), Positives = 158/417 (37%), Gaps = 66/417 (15%)
Query: 204 FRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHL 263
+ CQA+ SG+ + E + E + + E + ++C + T
Sbjct: 5118 YTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVD--------VTEKDPMTLECVVAGT-- 5167
Query: 264 AQEFPEIIIQ--KDKAIVAHNRH------GNKAVYSVMA-MVEHSGNYTCKVESSRISKV 314
PE+ ++ KD + +R+ N A + + + M + SG YT KVE+ S
Sbjct: 5168 ----PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSS 5223
Query: 315 SSIVVNITELFSKPELESSFTHLDQ--GERLNLSCSIPGAPPANFTIQKEDTIVSQTQDF 372
+ + + P T +D+ G +++ C + G+ P + K+ +S + +
Sbjct: 5224 CDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKY 5283
Query: 373 TKIASK------------SDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPR-----ISY 415
+ + D+ Y C K SN C + + +
Sbjct: 5284 RLVCHERSVSLEVNNLELEDTANYTC--------KVSNVAGDDACSGILTVKEPPSFLVK 5335
Query: 416 DAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK-------NSNDPAVFKDNP 468
+ + I T+E + + GT P + K L + K +++ ++ +
Sbjct: 5336 PGRQQAIPDSTVEFKA-ILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDA 5394
Query: 469 TEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEG 528
++ +Y C N + +L V P V+ + +SK+V++G+ L+C + G
Sbjct: 5395 SKTGQYTCHVTNDVGSDSCTTMLL---VTEPPKFVK-KLEASKIVKAGDSSRLECKI-AG 5449
Query: 529 SGPITYKFYREKEGKPF---YQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHAS 582
S I ++R + P Y+MT + A S E G++ C A N A S
Sbjct: 5450 SPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTS 5506
Score = 45.8 bits (107), Expect = 1e-04
Identities = 77/328 (23%), Positives = 119/328 (36%), Gaps = 48/328 (14%)
Query: 299 SGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPP---- 354
+G YTC + S S V+ + E S + S L G L + I G PP
Sbjct: 6808 TGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLP-GMSLTFTSVIRGTPPFKVK 6866
Query: 355 ----ANFTIQKEDTIVSQTQDFTKI----ASKSDSGTYICTAGIDKVVKKSNTVQIVVCE 406
+ + E +S T++ +SG Y C D S T + V E
Sbjct: 6867 WFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTND-AGSASCTTHLFVKE 6925
Query: 407 MLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENS-------TKNSN 459
+ + A F V G I + + +GT PIS +K ++ S T+ S
Sbjct: 6926 PATF--VKRLADFSVETGSPIVLEA-TYTGTPPISVSWIKDEYLISQSERCSITMTEKST 6982
Query: 460 DPAVFKDNPTEDVEYQCVADN------CHSHAKMLSEVLRVKVIAPVDEVQISILSSKVV 513
+ + + +Y C+ +N C + +L I P++ V+ I
Sbjct: 6983 ILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPY---FIEPLEHVEAVI------ 7033
Query: 514 ESGEDIVLQCAVNEGSGPITYKFYREK---EGKPFYQMTSNATQAFWTKQKASKEQEGEY 570
GE LQC V +G+ I +Y+E P Y+M A K GEY
Sbjct: 7034 --GEPATLQCKV-DGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEY 7090
Query: 571 YCTAFNRANHASSVPRSKILTVRVILAP 598
C A N +V S +L ++ P
Sbjct: 7091 SCKA---DNSVGAVASSAVLVIKARKLP 7115
Score = 45.8 bits (107), Expect = 1e-04
Identities = 111/552 (20%), Positives = 211/552 (38%), Gaps = 78/552 (14%)
Query: 83 YNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEA 142
Y ++ +++T + + +V D+G Y C N K + QL V+ P L+
Sbjct: 7258 YKMTLVENTATLTVLKVGKGDAGQYTCYAS-NIAGKDSCSAQLGVQEPPRFIKKLEPSRI 7316
Query: 143 I-QGGIVRVNCSV---PEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQ 198
+ Q R C + PE K + + ++ E+ E + + S + +LE
Sbjct: 7317 VKQDEFTRYECKIGGSPEIK--VLWYKDETEIQES----SKFRMSFVDSVAVLEMHNLSV 7370
Query: 199 DRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTI 258
+ + C+A +G S S+ + L K H T ++GA +H++C +
Sbjct: 7371 EDSGDYTCEAHNAAG-----SASSSTSLKVKEPPIFRKKPHPIET---LKGADVHLECEL 7422
Query: 259 QVT---HLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISK-- 313
Q T H++ + ++ K + + +++ + G Y CK + S
Sbjct: 7423 QGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTC 7482
Query: 314 VSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFT--------IQKEDTI 365
V SI + F K + S G+ + L +I GA P + +++ D I
Sbjct: 7483 VGSIALKAPPRFVKKLSDISTV---VGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNI 7539
Query: 366 -VSQTQDFTKI----ASKSDSGTYICTAGIDKVVKKSNTVQIVV--CEMLSQPRISYDAQ 418
+S +++ + +++G Y C D +++ V+ ++ +P
Sbjct: 7540 WISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPE-----S 7594
Query: 419 FEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK-------NSNDPAVFKDNPTE- 470
+V G T + C +++GT +S + K K L + K + + P++
Sbjct: 7595 IKVTTGDTCTLEC-TVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDS 7653
Query: 471 -----DVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAV 525
+V+ D+C + ++ + + E SG +V++C V
Sbjct: 7654 GVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETN--------GLSGSSVVMECKV 7705
Query: 526 NEGSGPITYKFYRE----KEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHA 581
GS PI+ ++ E G+ YQ T T + G+Y C A N A
Sbjct: 7706 -YGSPPISVSWFHEGNEISSGRK-YQTTLTDNTCALTVNMLEESDSGDYTCIA---TNMA 7760
Query: 582 SSVPRSKILTVR 593
S S LTVR
Sbjct: 7761 GSDECSAPLTVR 7772
Score = 43.9 bits (102), Expect = 5e-04
Identities = 91/441 (20%), Positives = 170/441 (38%), Gaps = 48/441 (10%)
Query: 40 KSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDD-----VLFYNISSMKSTESY 94
K P ++NG++ T +C ++ T P+ ++ +Y D + + IS + ++
Sbjct: 4866 KPSPVLVLRNGQSTTFEC--QITGT----PKIRVSWYLDGNEITAIQKHGISFIDGLATF 4919
Query: 95 FIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSV 154
I R+ +SGTY C N+ + +L V+ P+ L E ++ V + C V
Sbjct: 4920 QISGARVENSGTYVCEAR-NDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEV 4978
Query: 155 PEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGI 214
F + L+ N ++ K+ + + L + ++C I+S
Sbjct: 4979 TGTPP---FEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC---IVSNE 5032
Query: 215 HMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQK 274
S ST+ V + E S K + T ++ A T Q T I K
Sbjct: 5033 GGSCSCSTR---VALKEPPSFIKKIENTTTVLKSSA------TFQSTVAGSPPISITWLK 5083
Query: 275 DKAIVAHNRHGNKAVYSVMAMVE-------HSGNYTCKVESSRISKVSSIVVNITELFSK 327
D I+ + + + +A ++ HSG YTC+ ++ + + + E
Sbjct: 5084 DDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQI 5143
Query: 328 PELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQDFT-----KIAS----- 377
E S + + + + L C + G P K+ + ++ F+ +AS
Sbjct: 5144 VEKAKS-VDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQS 5202
Query: 378 --KSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESIS 435
K DSG Y D + V+ + + + + + G +I + C+ +S
Sbjct: 5203 VMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECK-VS 5261
Query: 436 GTLPISYQLLKTSKVLENSTK 456
G+LPIS Q K K + S K
Sbjct: 5262 GSLPISAQWFKDGKEISTSAK 5282
Score = 39.7 bits (91), Expect = 0.010
Identities = 125/566 (22%), Positives = 218/566 (38%), Gaps = 106/566 (18%)
Query: 53 LTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVI 112
+++Q F D S +++ F+ D+ F IS ++ T DSGTY C+
Sbjct: 4704 ISIQWFKDDQEIS-ASEKYKFSFH-DNTAFLEISQLEGT-----------DSGTYTCSA- 4749
Query: 113 VNNK--------EKTTAEYQLLVEGVPSPRVTLDKK---EAIQGGIVRVNCSVPEEKAPI 161
NK T E VE S V + + +A+ GG AP+
Sbjct: 4750 -TNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGT-----------APM 4797
Query: 162 HFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSES 221
TI+ + N+++ +D LE + ++ CQ + + + TS++
Sbjct: 4798 --TIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQ--LSNDVGTATSKA 4853
Query: 222 TKSELVTVTESFSTPKF--HISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQ---KDK 276
T + V E P+F SP ++ G +C I T P+I +
Sbjct: 4854 T----LFVKEP---PQFIKKPSPVLVLRNGQSTTFECQITGT------PKIRVSWYLDGN 4900
Query: 277 AIVAHNRHG-----NKAVYSVM-AMVEHSGNYTCKVESSRISKVSSIVVNITE--LFSKP 328
I A +HG A + + A VE+SG Y C+ + + SI + + E F +
Sbjct: 4901 EITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIR- 4959
Query: 329 ELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQDFTKI------------A 376
E + + + L C + G PP T K + + ++ +T
Sbjct: 4960 --ELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKC 5017
Query: 377 SKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISG 436
SD+G Y C ++ S + ++ + E S + + + T + +++G
Sbjct: 5018 DPSDTGEYQCIVS-NEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQ---STVAG 5073
Query: 437 TLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHS-----HAKMLSEV 491
+ PIS LK ++L+ ++ N F D+ ++ + V DN HS AK S V
Sbjct: 5074 SPPISITWLKDDQILD---EDDNVYISFVDS-VATLQIRSV-DNGHSGRYTCQAKNESGV 5128
Query: 492 LRVKVIAPVDEVQISILSSKVVESGE--DIVLQCAVNEGSGPITYKFYREKEGKP----- 544
R V E + +K V+ E + L+C V +G K K+GK
Sbjct: 5129 ERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVV---AGTPELKVKWLKDGKQIVPSR 5185
Query: 545 FYQMTSNATQAFWTKQKASKEQEGEY 570
++ M+ A + Q K+ G+Y
Sbjct: 5186 YFSMSFENNVASFRIQSVMKQDSGQY 5211
Score = 38.9 bits (89), Expect = 0.017
Identities = 50/213 (23%), Positives = 77/213 (36%), Gaps = 48/213 (22%)
Query: 287 KAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLS 346
K + S V+ + K+E+S+++K QGE + L
Sbjct: 6351 KDMCSAQLSVKEPPKFVKKLEASKVAK-------------------------QGESIQLE 6385
Query: 347 CSIPGAPPANFTIQKEDTIVSQTQDFT------------KIASKSDSGTYICTAGIDKVV 394
C I G+P + + D+ + ++ + AS DSG YIC A
Sbjct: 6386 CKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGD 6445
Query: 395 KKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENS 454
+T V + + S +KG + ++CE ISGT P +K K + NS
Sbjct: 6446 ASCSTALTVKAPPVFTQKPS---PVGALKGSDVILQCE-ISGTPPFEVVWVKDRKQVRNS 6501
Query: 455 TKNSNDPAVFKDN------PTEDV-EYQCVADN 480
K F + DV EY C A N
Sbjct: 6502 KKFKITSKHFDTSLHILNLEASDVGEYHCKATN 6534
Score = 38.5 bits (88), Expect = 0.023
Identities = 69/313 (22%), Positives = 128/313 (40%), Gaps = 48/313 (15%)
Query: 299 SGNYTCKVESSRISKVSSIVVNITE---LFSKPELESSFTHLDQGERLNLSCSIPGAPPA 355
+G Y C+V + S + S V + E K E SS +G ++ G+ P
Sbjct: 4460 AGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL----RGGTAAFQATLKGSLPI 4515
Query: 356 NFTIQKEDTIVSQTQDF-------------TKIASKSDSGTYICTAGIDKVVKK-SNTVQ 401
T K+ +++ + + I K D G Y+C A D +++ S +
Sbjct: 4516 TVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHD-GKYVCQAKNDAGIQRCSALLS 4574
Query: 402 IVVCEMLSQPRISYDAQFEVIKGQ--TIEVRCESISGTLPISYQLLKTSKVLENSTKN-- 457
+ +++ +S D V +G T++V+ SGT I+ + K + L +K
Sbjct: 4575 VKEPATITEEAVSID----VTQGDPATLQVK---FSGTKEITAKWFKDGQELTLGSKYKI 4627
Query: 458 --SNDPAVFKDNPTE-----DVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSS 510
++ ++ K TE + ++ D S K VL + +I P ++ + S
Sbjct: 4628 SVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL-IIPPSFTKKLKKMDS 4686
Query: 511 KVVESGEDIVLQCAVNEGSGPITYKFYREKE---GKPFYQMTSNATQAFWTKQKASKEQE 567
G I L+C V GS PI+ +++++ + Y+ + + AF +
Sbjct: 4687 I---KGSFIDLECIV-AGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDS 4742
Query: 568 GEYYCTAFNRANH 580
G Y C+A N+A H
Sbjct: 4743 GTYTCSATNKAGH 4755
Score = 38.1 bits (87), Expect = 0.030
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 22/113 (19%)
Query: 294 AMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHL--DQGERLNLSCSIPG 351
A + +G YTCKV + S + + + I E P + T + +GE + LSC + G
Sbjct: 8312 AGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQG 8371
Query: 352 APP-------ANFTIQKED---------TIVSQTQDFTKIASKSDSGTYICTA 388
+ P A I+ D T V + +D +K+DSG Y+C A
Sbjct: 8372 SEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRD----VAKADSGDYVCKA 8420
Score = 37.7 bits (86), Expect = 0.039
Identities = 72/350 (20%), Positives = 134/350 (38%), Gaps = 60/350 (17%)
Query: 260 VTHLAQEFPEIIIQK-DKAIVAHNRH-----GNKAVYSVM-AMVEHSGNYTCKVESSRIS 312
V +++ E+I K D+ I+ R+ G K + + A +E +GNY C++ SSR
Sbjct: 12483 VCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTD 12542
Query: 313 KVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQ-KEDTIVSQTQD 371
+ E SKP+ + +GE+ CSI +F +Q K D ++ D
Sbjct: 12543 GKVKVHELAAEFISKPQ----NLEILEGEKAEFVCSI---SKESFPVQWKRDDKTLESGD 12595
Query: 372 -------------FTKIASKSDSGTYICTAGIDKVVKKSNTVQ---IVV----CEMLSQP 411
K A+ D GTY+ G + ++ IVV + Q
Sbjct: 12596 KYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQ 12655
Query: 412 RISYDAQFEVIKGQTIEVRCESI----SGTLPISYQLLKTSKVLENSTKNSNDPAVFKDN 467
+ ++ + + R E S + + L+ T ++ + + +D A + +
Sbjct: 12656 EVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRD---AHLDDQANYNVS 12712
Query: 468 PTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNE 527
T +N S A ++ E ++++ P+ +++ + + C VN
Sbjct: 12713 LTNH-----RGENVKSAANLIVEEEDLRIVEPLKDIE--------TMEKKSVTFWCKVNR 12759
Query: 528 GSGPITYKFYREKEGKPFYQMTSNATQAF---WTKQKASKEQEGEYYCTA 574
+ +T K+ + E PF S + T + EGEY TA
Sbjct: 12760 LN--VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA 12807
Score = 37.4 bits (85), Expect = 0.050
Identities = 86/401 (21%), Positives = 157/401 (39%), Gaps = 71/401 (17%)
Query: 34 INSVDMKSLPDWTVQNGKNLTLQCFADVSTTSHV----KPQHQMLFYKDDVLFYNISSMK 89
+ V+ + PD+ + TL A +S V +P ++ + KD++ N ++++
Sbjct: 20765 VEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE 20824
Query: 90 STESY---FIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGG 146
+TES+ IPE YD+G + T I N K + + V P P + L + I
Sbjct: 20825 NTESFTLLIIPECNRYDTGKFVMT-IENPAGKKSGFVNVRVLDTPGPVLNL-RPTDITKD 20882
Query: 147 IVRVNCSVP---EEKAPIHFTIEKLELNEKMVKLKREKNSR------------------- 184
V ++ +P ++ +EK E K K +
Sbjct: 20883 SVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVM 20942
Query: 185 DQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFH--ISP 242
+N + P E + V + + S + + TKS TV+ ++ PK
Sbjct: 20943 AENEYGIGEPTETTEPVKASEAPSPPDS---LNIMDITKS---TVSLAWPKPKHDGGSKI 20996
Query: 243 TGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNY 302
TG ++E + K + Q TH+ ++ + +V + G + + VMA+ +S
Sbjct: 20997 TGYVIEAQR---KGSDQWTHIT------TVKGLECVVRNLTEGEEYTFQVMAV--NSAGR 21045
Query: 303 TCKVESSRISKVSSIVVNITELFSKPELESSFTHL---DQGERLNLSCSIPGAPPANFTI 359
+ ES ++V + + +L + L G+ + + + G P T
Sbjct: 21046 SAPRES------RPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW 21099
Query: 360 QKEDTIVSQTQ--DFTKIAS----------KSDSGTYICTA 388
+K D I+ QTQ +F A+ +SDSG Y TA
Sbjct: 21100 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTA 21140
Score = 37.0 bits (84), Expect = 0.066
Identities = 71/309 (22%), Positives = 115/309 (37%), Gaps = 39/309 (12%)
Query: 300 GNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFT- 358
GNYTC + S V+ + E S + E + G+ + + I G PP
Sbjct: 5868 GNYTCVAANVAGSDECRAVLTVQEPPSFVK-EPEPLEVLPGKNVTFTSVIRGTPPFKVNW 5926
Query: 359 --------------IQKEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVV 404
I EDT V++ + F S SG Y C + + S T ++ V
Sbjct: 5927 FRGARELVKGDRCNIYFEDT-VAELELFN--IDISQSGEYTCVVS-NNAGQASCTTRLFV 5982
Query: 405 CEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPIS-------YQLLKTSKVLENSTKN 457
E + + D E K +E + +GTLPIS + + + K +T+
Sbjct: 5983 KEPAAFLKRLSDHSVEPGKSIILE---STYTGTLPISVTWKKDGFNITTSEKCNIVTTEK 6039
Query: 458 SNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGE 517
+ + + +Y C +N + + L + P ++ L + V G+
Sbjct: 6040 TCILEILNSTKRDAGQYSCEIEN--EAGRDVCGALVSTLEPPYFVTELEPLEAAV---GD 6094
Query: 518 DIVLQCAVNEGSGPITYKFYR---EKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTA 574
+ LQC V G+ IT +Y+ + P Y+ A K + GEY C A
Sbjct: 6095 SVSLQCQV-AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 6153
Query: 575 FNRANHASS 583
N ASS
Sbjct: 6154 ENSIGTASS 6162
Score = 36.2 bits (82), Expect = 0.11
Identities = 101/514 (19%), Positives = 193/514 (37%), Gaps = 61/514 (11%)
Query: 36 SVDMKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLF-----YNISSMKS 90
+V K+L + V + L C +VS KP ++++YK D Y I +
Sbjct: 12463 AVFTKNLANIEVSETDTIKLVC--EVS-----KPGAEVIWYKGDEEIIETGRYEILTEGR 12515
Query: 91 TESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRV 150
I + D+G Y C + + + ++L E + P+ E ++G
Sbjct: 12516 KRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQ----NLEILEGEKAEF 12571
Query: 151 NCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARI 210
CS+ +E P+ + + L E K + + + V+ + +++ + AR
Sbjct: 12572 VCSISKESFPVQWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAAR- 12629
Query: 211 ISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEI 270
+ H+ E + + + + + EGA+ K + I
Sbjct: 12630 -AAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAK--AKWFRNEEAIFDSSKYI 12686
Query: 271 IIQKDKAIVAHNRHG---NKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSK 327
I+QKD R ++A Y+V ++ H G V+S+ V + I E
Sbjct: 12687 ILQKDLVYTLRIRDAHLDDQANYNV-SLTNHRGE---NVKSAANLIVEEEDLRIVEPLKD 12742
Query: 328 PEL--ESSFTHLDQGERLNLSC-------SIPGAPPANFTIQKEDTIVSQTQDFTKIASK 378
E + S T + RLN++ +P ++ + K +++ K
Sbjct: 12743 IETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLT-----IKDCGF 12797
Query: 379 SDSGTYICTAGIDKVVKKSNTVQIVV--CEMLSQPRISY--DAQFEVIKGQTIEVRCESI 434
D G YI TAG DK V + ++ E L ++ DA F + ++ E
Sbjct: 12798 PDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVF------SCQLSREKA 12851
Query: 435 SGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTED-VEYQCVADNCHSHAKMLSEVLR 493
+ + + +K K + S + KD +D EY C ++ S A++ E +
Sbjct: 12852 NVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIP 12911
Query: 494 VKVIAPVDEVQISILSSKVVESGEDIVLQCAVNE 527
V++I P ++ + G D+V +N+
Sbjct: 12912 VEIIRPPQDI--------LEAPGADVVFLAELNK 12937
Score = 35.4 bits (80), Expect = 0.19
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Query: 482 HSHAKMLSEVLRVKVIAPVD-----EVQISILSSKVVESGEDIVLQCAVNEGSGPITYKF 536
H ++E RV APV+ +S L + V GE + L+C ++ P T +
Sbjct: 920 HGREAKVTETARVP--APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSP-TVTW 976
Query: 537 YREK---EGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASS 583
YRE E +Q+T + A ++A E G + C+A N A S+
Sbjct: 977 YREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVST 1026
Score = 34.3 bits (77), Expect = 0.43
Identities = 64/329 (19%), Positives = 121/329 (36%), Gaps = 47/329 (14%)
Query: 43 PDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYF------- 95
P + + G++ L C S P Q+ ++K++ +S + YF
Sbjct: 3745 PSYLMLPGESARLHCKLKGS------PVIQVTWFKNNK---ELSESNTVRMYFVNSEAIL 3795
Query: 96 -IPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSV 154
I +V++ DSG+Y C VN+ + +++++ PS TL+ + ++G + C V
Sbjct: 3796 DITDVKVEDSGSYSCEA-VNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEV 3854
Query: 155 PEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGI 214
F I + +++ K+ + ++ V LE V + C
Sbjct: 3855 ---SGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYEC-------- 3903
Query: 215 HMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEI---- 270
+ +E K + P F +I G Q T+Q E +
Sbjct: 3904 -VVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQ---TVTLQAAVRGSEPISVTWMK 3959
Query: 271 ---IIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVS---SIVVNITEL 324
+I++D I +G + + G YTC E+ S+ S IV ++
Sbjct: 3960 GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKI 4019
Query: 325 FSKPELESSFTHLDQGERLNLSCSIPGAP 353
+ EL + G+ L ++ G P
Sbjct: 4020 IERAEL----IQVTAGDPATLEYTVAGTP 4044
Score = 34.3 bits (77), Expect = 0.43
Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 7/103 (6%)
Query: 77 KDDVLF---YNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSP 133
K+ VL+ N + T + IP+ R D+G Y T VNN + E +L V G P P
Sbjct: 16161 KEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITA-VNNLGTASKEMRLNVLGRPGP 16219
Query: 134 RVTLDKKEAIQGGIVRVNCSVPEEKAP---IHFTIEKLELNEK 173
V K E++ + ++ P++ ++ IEK E N K
Sbjct: 16220 PVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRK 16262
Score = 33.9 bits (76), Expect = 0.56
Identities = 107/488 (21%), Positives = 178/488 (36%), Gaps = 84/488 (17%)
Query: 39 MKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPE 98
+K + D G+ +TLQ S V ++D +S IP+
Sbjct: 3927 VKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKI-KMSFSNGVAVLIIPD 3985
Query: 99 VRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEK 158
V+I G Y C + N T+ +L+V+ P +++ E IQ V P
Sbjct: 3986 VQISFGGKYTC-LAENEAGSQTSVGELIVK---EPAKIIERAELIQ-----VTAGDP--- 4033
Query: 159 APIHFTIEKL-ELNEK-------MVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARI 210
A + +T+ EL K +V K+ + S N L+F E +
Sbjct: 4034 ATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAE------LHDSGQY 4087
Query: 211 ISGIHMQTSESTKSELVTVTESFSTPKFH--ISPTGMIMEGAQLHIKCTIQVTHLAQEFP 268
I + S+ TV + P F + ++ G + C I A P
Sbjct: 4088 TFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGT-CRLDCKI-----AGSLP 4141
Query: 269 EII--IQKDKAIVAHNRH------GNKAVYSVMAMVEHSGNYTCKVESSRISKVSS---I 317
+ + K I A +R+ G ++ + + +GN+TC+ +S SK SS I
Sbjct: 4142 MRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALI 4201
Query: 318 VVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQK--EDTIVSQTQDFTK- 374
V +KP + G + L + G+ P K ++ + + TK
Sbjct: 4202 VQEPPSFVTKPGSKDVL----PGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKE 4257
Query: 375 ---------IASKSDSGTYICTAGIDKVVKKSNTVQIVVC--EMLSQPRISYDAQFE--- 420
+ SDSGTY C K SN V C + + ++ + E
Sbjct: 4258 ALESSLELYLVKTSDSGTYTC--------KVSNVAGGVECSANLFVKEPATFVEKLEPSQ 4309
Query: 421 -VIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNS----NDPAVFK--DNPTEDV- 472
+ KG ++ C+ ++GT PI + ++ S+K+ AV + D ED
Sbjct: 4310 LLKKGDATQLACK-VTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSG 4368
Query: 473 EYQCVADN 480
EY C A N
Sbjct: 4369 EYMCEAQN 4376
Score = 33.9 bits (76), Expect = 0.56
Identities = 21/65 (32%), Positives = 42/65 (64%), Gaps = 3/65 (4%)
Query: 96 IPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRV-TLDKK-EAIQGGIVRVNCS 153
I +V++ D+G Y C + + NKEKT+ +L+VE +P V TL+++ ++G + ++C
Sbjct: 11177 IIDVQLSDAGEYTCVLRLGNKEKTSTA-KLVVEELPVRFVKTLEEEVTVVKGQPLYLSCE 11235
Query: 154 VPEEK 158
+ +E+
Sbjct: 11236 LNKER 11240
Score = 33.9 bits (76), Expect = 0.56
Identities = 30/148 (20%), Positives = 59/148 (39%), Gaps = 7/148 (4%)
Query: 445 LKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQ 504
L TS+ + S++ K+ +D+ + K LS ++KV+
Sbjct: 11613 LHTSRTVLISSEGKTHKLEMKEVTLDDIS------QIKAQVKELSSTAQLKVLEADPYFT 11666
Query: 505 ISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASK 564
+ + VE E I L+C V++ +K E P Y + ++ + +KA
Sbjct: 11667 VKLHDKTAVEKDE-ITLKCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADL 11725
Query: 565 EQEGEYYCTAFNRANHASSVPRSKILTV 592
+ +GEY C A+ ++++ V
Sbjct: 11726 KDKGEYVCDCGTDKTKANVTVEARLIKV 11753
Score = 33.5 bits (75), Expect = 0.73
Identities = 65/324 (20%), Positives = 124/324 (38%), Gaps = 56/324 (17%)
Query: 298 HSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANF 357
++G Y C++++ + + + + E E T + GE L C + G P +
Sbjct: 5677 NAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMT-VTVGETCTLECKVAGTPELSV 5735
Query: 358 TIQKEDTIVSQTQD-----FTKIAS-------KSDSGTYICTAGIDKVVKKSNTVQIVVC 405
K+ +++ +Q + KI+S + D+GTY T + V KS+ +V
Sbjct: 5736 EWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTY--TFQVQNNVGKSSCTAVVDV 5793
Query: 406 EMLSQPRISYDAQFE---VIKGQTIEVRCESISGTLPIS----YQLLKTSKVLENSTKNS 458
+ P S+ + + + G + + C+ ++G+ PIS ++ K + T S
Sbjct: 5794 SDRAVPP-SFTRRLKNTGGVLGASCILECK-VAGSSPISVAWFHEKTKIVSGAKYQTTFS 5851
Query: 459 NDPAVFKDNPTEDVE---YQCVA------DNCHSHAKMLSEVLRVKVIAPVDEVQISILS 509
++ + N + + Y CVA D C + + VK P++
Sbjct: 5852 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLE-------- 5903
Query: 510 SKVVESGEDIVLQCAVNEGSGPITYKFYREKEG-------KPFYQMTSNATQAFWTKQKA 562
V G+++ +V G+ P ++R +++ T + F
Sbjct: 5904 ---VLPGKNVTF-TSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELF----NI 5955
Query: 563 SKEQEGEYYCTAFNRANHASSVPR 586
Q GEY C N A AS R
Sbjct: 5956 DISQSGEYTCVVSNNAGQASCTTR 5979
Score = 33.1 bits (74), Expect = 0.95
Identities = 50/207 (24%), Positives = 88/207 (42%), Gaps = 28/207 (13%)
Query: 374 KIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQT----IEV 429
K A D G Y+C G DK K+N V ++ + Y EV G+T IE+
Sbjct: 11721 KKADLKDKGEYVCDCGTDKT--KANVT--VEARLIKVEKPLYGV--EVFVGETAHFEIEL 11774
Query: 430 RCESISGTLPISYQLLKTS---KVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAK 486
+ G + Q L S +++E+ K+ + T +V +Q A N S A
Sbjct: 11775 SEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQ--AANAKSAAN 11832
Query: 487 MLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYR---EKEGK 543
+ + L + I P+ +V KV E ++ +C V+ P T+++ + E G
Sbjct: 11833 LKVKELPLIFITPLSDV-------KVFEK-DEAKFECEVSR--EPKTFRWLKGTQEITGD 11882
Query: 544 PFYQMTSNATQAFWTKQKASKEQEGEY 570
+++ + T+ + A+ E E +Y
Sbjct: 11883 DRFELIKDGTKHSMVIKSAAFEDEAKY 11909
Score = 32.0 bits (71), Expect = 2.1
Identities = 65/277 (23%), Positives = 105/277 (37%), Gaps = 53/277 (19%)
Query: 294 AMVEHSGNYTCKVESS--RISKVSSIVVNITELFS-KPELESSFTHLDQGERLNLSCSIP 350
A E SG+Y C+ + S +++ V +F+ KP + +G + L C I
Sbjct: 6427 ASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGAL----KGSDVILQCEIS 6482
Query: 351 GAPPANFTIQKEDTIVSQTQDFTKIASK-------------SDSGTYICTAGIDKVVKKS 397
G PP K+ V ++ F KI SK SD G Y C K +
Sbjct: 6483 GTPPFEVVWVKDRKQVRNSKKF-KITSKHFDTSLHILNLEASDVGEYHC--------KAT 6533
Query: 398 NTVQIVVC----EMLSQPR-ISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLE 452
N V C + PR + + + G +E+R + G PIS LK +
Sbjct: 6534 NEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRA-IVEGFQPISVVWLKDRGEVI 6592
Query: 453 NSTKNSNDPAVFKDN----------PTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDE 502
++N+ F DN + +Y C N + + S VL V A + E
Sbjct: 6593 RESENTR--ISFIDNIATLQLGSPEASNSGKYICQIKN-DAGMRECSAVLTVLEPARIIE 6649
Query: 503 VQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYRE 539
V +G L+C V G+ ++ K++++
Sbjct: 6650 KP----EPMTVTTGNPFALECVVT-GTPELSAKWFKD 6681
Score = 30.4 bits (67), Expect = 6.2
Identities = 43/201 (21%), Positives = 83/201 (41%), Gaps = 28/201 (13%)
Query: 498 APVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYRE--KEGKP--FYQMTSNAT 553
AP + +I +++G+ IVL A++ P+ + + K+ +P Q+TS T
Sbjct: 20375 APTIVLDPTIKDGLTIKAGDTIVLN-AISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 20433
Query: 554 QAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGLIAVVIIGVII 613
+ T + A+++ GEY TA N + + + V V+ P G + + +
Sbjct: 20434 SSMLTIKYATRKDAGEYTITATNPFG-----TKVEHVKVTVLDVPGPPGPVEISNVSAEK 20488
Query: 614 ALLI---------IAAKCYFLRKAKAKQM-------PVEMSRPAVPLLNSNNEKMSDPNM 657
A L K Y L K + ++ ++ R L NE + +
Sbjct: 20489 ATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIF--RV 20546
Query: 658 EANSHYGHNDDVRNHAMKPIN 678
A +HYG + V++ +K ++
Sbjct: 20547 SAVNHYGKGEPVQSEPVKMVD 20567
Score = 30.0 bits (66), Expect = 8.1
Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 14/94 (14%)
Query: 309 SRISKVSSIVVNITELFSKPELESSFTHLD--QGERLNLSCSIPGAPPANFTIQKEDTIV 366
+++++ + + + + P L S ++ +GE + L C I G P T +ED +
Sbjct: 924 AKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI 983
Query: 367 SQTQDF------------TKIASKSDSGTYICTA 388
+ DF + A DSG + C+A
Sbjct: 984 ESSIDFQITFQSGIARLMIREAFAEDSGRFTCSA 1017
Score = 30.0 bits (66), Expect = 8.1
Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 10/107 (9%)
Query: 271 IIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELF----- 325
I + DK + +++ + ++ + V G YTCK + S + + +TE +
Sbjct: 3496 IYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFL 3554
Query: 326 SKPELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQDF 372
S+P+ ++F G+ C++ G P QK+ +S + ++
Sbjct: 3555 SRPKSLTTFV----GKAAKFICTVTGTPVIETIWQKDGAALSPSPNW 3597
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 62.0 bits (149), Expect = 2e-09
Identities = 90/435 (20%), Positives = 177/435 (40%), Gaps = 54/435 (12%)
Query: 230 TESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNR----HG 285
+ + P +SP I + + CT + ++ + + + ++V H R
Sbjct: 64 SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHW----VSNNLSVVFHERMQLSKD 119
Query: 286 NKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKP---ELESSFT-----HL 337
K + ++ E SG Y C+ + +S+ S + + P +LES +
Sbjct: 120 GKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEV 179
Query: 338 DQGERLNLSCSIPGAPPANFTIQKEDTIVSQT-QDFTKIA-SKSDSGTYICTAGIDKVVK 395
+G + PP +T D+I+S T + FT A S+ G Y C
Sbjct: 180 MEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
Query: 396 KS-NTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISY----QLLKTSKV 450
S T+++ V E L+ P++ + V +++++ C++++ ++ + + Q L S+
Sbjct: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
Query: 451 LENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQIS---- 506
L+ S N + + Y C N S A+ SE L + + D+V I+
Sbjct: 300 LQLSADN-RTLIIHGLQRNDTGPYACEVWNWGSRAR--SEPLELTINYGPDQVHITRESA 356
Query: 507 --ILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASK 564
++S+ E + LQC + K G + ++T +Q +
Sbjct: 357 SEMISTIEAELNSSLTLQC------------WAESKPGAEYRWTLEHSTGEHLGEQLIIR 404
Query: 565 ----EQEGEYYCTAFNRANHASSVPRSKILTVRVI---LAPWKKGLIAVVIIGVIIALLI 617
E +G Y CTA +N + + RS + V+V+ + G IA ++IG++ + +
Sbjct: 405 ALTWEHDGIYNCTA---SNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAV 461
Query: 618 IAAKCYFLRKAKAKQ 632
+ YFL A++
Sbjct: 462 ASELGYFLYIRNARR 476
Score = 35.0 bits (79), Expect = 0.25
Identities = 58/234 (24%), Positives = 90/234 (38%), Gaps = 32/234 (13%)
Query: 474 YQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPIT 533
YQC A + + S+ + + V D V+I + S V SGE + V EGS +
Sbjct: 136 YQCEARDALLSQR--SDPIFLDVKYGPDPVEIKLESG--VASGEVV----EVMEGS---S 184
Query: 534 YKFYREKEGKPFYQMT--------SNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVP 585
F E + P T S+ T+ F T S+E EG Y C N A H SS+
Sbjct: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTF-TIHAVSREHEGLYRCLVSNSATHLSSLG 243
Query: 586 RSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLL 645
K+ + + P ++ + L+ A + + + V+ PLL
Sbjct: 244 TLKVRVLETLTMP--------QVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLL 295
Query: 646 NSNNEKMSDPNMEANSHYGHNDDVRNHAMKPIN----DNKEPLNSDVQYTEVQV 695
S + ++S N H +D +A + N EPL + Y QV
Sbjct: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQV 349
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 62.0 bits (149), Expect = 2e-09
Identities = 90/435 (20%), Positives = 177/435 (40%), Gaps = 54/435 (12%)
Query: 230 TESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNR----HG 285
+ + P +SP I + + CT + ++ + + + ++V H R
Sbjct: 64 SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHW----VSNNLSVVFHERMQLSKD 119
Query: 286 NKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKP---ELESSFT-----HL 337
K + ++ E SG Y C+ + +S+ S + + P +LES +
Sbjct: 120 GKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEV 179
Query: 338 DQGERLNLSCSIPGAPPANFTIQKEDTIVSQT-QDFTKIA-SKSDSGTYICTAGIDKVVK 395
+G + PP +T D+I+S T + FT A S+ G Y C
Sbjct: 180 MEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
Query: 396 KS-NTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISY----QLLKTSKV 450
S T+++ V E L+ P++ + V +++++ C++++ ++ + + Q L S+
Sbjct: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
Query: 451 LENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQIS---- 506
L+ S N + + Y C N S A+ SE L + + D+V I+
Sbjct: 300 LQLSADN-RTLIIHGLQRNDTGPYACEVWNWGSRAR--SEPLELTINYGPDQVHITRESA 356
Query: 507 --ILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASK 564
++S+ E + LQC + K G + ++T +Q +
Sbjct: 357 SEMISTIEAELNSSLTLQC------------WAESKPGAEYRWTLEHSTGEHLGEQLIIR 404
Query: 565 ----EQEGEYYCTAFNRANHASSVPRSKILTVRVI---LAPWKKGLIAVVIIGVIIALLI 617
E +G Y CTA +N + + RS + V+V+ + G IA ++IG++ + +
Sbjct: 405 ALTWEHDGIYNCTA---SNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAV 461
Query: 618 IAAKCYFLRKAKAKQ 632
+ YFL A++
Sbjct: 462 ASELGYFLYIRNARR 476
Score = 35.0 bits (79), Expect = 0.25
Identities = 58/234 (24%), Positives = 90/234 (38%), Gaps = 32/234 (13%)
Query: 474 YQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPIT 533
YQC A + + S+ + + V D V+I + S V SGE + V EGS +
Sbjct: 136 YQCEARDALLSQR--SDPIFLDVKYGPDPVEIKLESG--VASGEVV----EVMEGS---S 184
Query: 534 YKFYREKEGKPFYQMT--------SNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVP 585
F E + P T S+ T+ F T S+E EG Y C N A H SS+
Sbjct: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTF-TIHAVSREHEGLYRCLVSNSATHLSSLG 243
Query: 586 RSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLL 645
K+ + + P ++ + L+ A + + + V+ PLL
Sbjct: 244 TLKVRVLETLTMP--------QVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLL 295
Query: 646 NSNNEKMSDPNMEANSHYGHNDDVRNHAMKPIN----DNKEPLNSDVQYTEVQV 695
S + ++S N H +D +A + N EPL + Y QV
Sbjct: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQV 349
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 60.8 bits (146), Expect = 4e-09
Identities = 114/546 (20%), Positives = 200/546 (36%), Gaps = 75/546 (13%)
Query: 96 IPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVP 155
IP ++ D+G Y C V VN + + +Y + V P I+G N +P
Sbjct: 2835 IPRAKVEDAGRYTC-VAVNEAGEDSLQYDVRVLVPP----------IIKG----ANSDLP 2879
Query: 156 EEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIH 215
EE + +E R +D P+ E D F RI+ ++
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQ------PLLEDDH-HKFLSNGRILQILN 2932
Query: 216 MQTSESTKSELVTVTESFSTPKF-----HISPT--GMIMEGAQLHIKCTIQVTHLAQEF- 267
Q ++ + V + S K+ H+ P+ G E + + I +T F
Sbjct: 2933 TQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP 2992
Query: 268 -PEIIIQKDKAIVAHNRH-----GNKAVYSVMAMVEHSGNYTCKV--ESSRISKVSSIVV 319
P++ K++ + N + G + + + A V G YTC ++ K S+ V
Sbjct: 2993 PPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Query: 320 NITELFSKPELES-SFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQD------- 371
+ + ES S ++ +G ++L C PP T K +++++
Sbjct: 3053 YVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG 3112
Query: 372 ---FTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIE 428
K A SD+G Y+C A I+ + + V S + E I +
Sbjct: 3113 QMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPSIEGPEREVIVETI-SNPVT 3170
Query: 429 VRCESISGTLPISYQLLKTSKVLENS-------TKNSNDPAVFKDNPTEDVEYQCVADNC 481
+ C++ +G P + LK K +ENS + + + ++ Y C+A N
Sbjct: 3171 LTCDA-TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNM 3229
Query: 482 HSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKE 541
A+ + + + P I S V GE++ L C N P+ K+
Sbjct: 3230 EGKAQ---KYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWL---KD 3283
Query: 542 GKPF-----YQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVIL 596
GKP ++ +A + A G+Y C A N A +I + V +
Sbjct: 3284 GKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE-----EDRIFNLNVYV 3338
Query: 597 APWKKG 602
P +G
Sbjct: 3339 TPTIRG 3344
Score = 53.1 bits (126), Expect = 9e-07
Identities = 105/476 (22%), Positives = 185/476 (38%), Gaps = 70/476 (14%)
Query: 44 DWTVQNGKNLTLQCFADVSTTSHVKPQH--QMLFYKDDVLFYNISSMKSTESYFIPEVRI 101
D +++ G N+TL C+ +K + M + +IS ++ T + FI +
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR-TGALFILNLWA 859
Query: 102 YDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEA--IQGGIVRVNCSVPEEKA 159
D GTY C N K +E + V G+ +P + + A I+G + + C++ A
Sbjct: 860 SDKGTYICEA-ENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTL---LA 915
Query: 160 PIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTS 219
+ N M+ R + +E V+ QD + C A ++G T+
Sbjct: 916 GNPIPERRWIKNSAMLLQNPYITVRSDGSLHIE-RVQLQDGG-EYTCVASNVAG----TN 969
Query: 220 ESTKSELVTVTESFSTPKFHISPTGMIMEGAQL-----HIKCTIQVTHLAQEFPEIIIQK 274
T S +V H+ PT I G Q+ I T+ P +I K
Sbjct: 970 NKTTSVVV-----------HVLPT--IQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSK 1016
Query: 275 DKAIVA-----HNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPE 329
+++ + + ++Y V E SG Y C ++ + + V +T ++ +P
Sbjct: 1017 KGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNT--AGYAKRKVQLT-VYVRPR 1073
Query: 330 LESSFTHLDQ----------GERLNLSCSIPGAPPANFTIQKEDTIVSQ-TQDFTKIAS- 377
+ L Q GE + L C + PP T KE ++S + T + S
Sbjct: 1074 VFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG 1133
Query: 378 --------KSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQ-FEVIKGQTIE 428
SDSG Y+C A N Q V + P+I + +V GQ ++
Sbjct: 1134 SMKITETRTSDSGMYLCVA----TNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVD 1189
Query: 429 VRCESISGTLPISYQLLKTSKVLENSTKNSNDP----AVFKDNPTEDVEYQCVADN 480
+ C + LP+ S +L + + ++P ++ + P++ Y CVA N
Sbjct: 1190 IPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 49.3 bits (116), Expect = 1e-05
Identities = 82/381 (21%), Positives = 149/381 (39%), Gaps = 63/381 (16%)
Query: 215 HMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQK 274
H +E++++ L V + TP + +++ A L K T A+ + E+I++
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDNVLL--ANLLGKYT------AEPYGELILEN 4228
Query: 275 DKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSF 334
++E SG YTC ++ ++ + + L + EL
Sbjct: 4229 -------------------VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDV 4269
Query: 335 THLDQGERLNLSCSIPGAP-------------PANFTIQKEDTIVSQTQDFTKIASKSDS 381
+ L++GE+L LSC G P PA+F D++ ++ + SK DS
Sbjct: 4270 S-LNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHF-----DSVNGHSELVIERVSKEDS 4323
Query: 382 GTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPIS 441
GTY+CTA + V + V + + Y + + G + CE + G +
Sbjct: 4324 GTYVCTA--ENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCE-VKGDPTPT 4380
Query: 442 YQLLKTSKVLENSTK----NSNDPAVFKDNPTEDVEYQCVADN-CHSHAKMLSEVLRVKV 496
Q + +E S + + A++ + +Y CVA N + +S L+
Sbjct: 4381 IQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Query: 497 IAPVDEVQISILSSKVVESGEDIVLQC-AVNEGSGPITYKFYREKEGKPFYQMTSNATQA 555
I ++ V+ V+ +G I+L C A E IT+ R+ + + +
Sbjct: 4441 IITLEPVE------TVINAGGKIILNCQATGEPQPTITWS--RQGHSISWDDRVNVLSNN 4492
Query: 556 FWTKQKASKEQEGEYYCTAFN 576
A KE E+ C A N
Sbjct: 4493 SLYIADAQKEDTSEFECVARN 4513
Score = 48.1 bits (113), Expect = 3e-05
Identities = 72/318 (22%), Positives = 127/318 (39%), Gaps = 36/318 (11%)
Query: 299 SGNYTCKV--ESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPAN 356
+G+YTC E+ R + ++ V +F + + S ++ G + L C + G P
Sbjct: 767 AGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVS---MEIGSNVTLPCYVQGYPEPT 823
Query: 357 FTIQKEDTIVSQTQDFTKIASK--------------SDSGTYICTAGIDKVVKKSNTVQI 402
++ D + ++ F+ + SD GTYIC A + K +
Sbjct: 824 IKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA--ENQFGKIQSETT 881
Query: 403 VVCEMLSQPRISYDAQF-EVIKGQTIEVRCESISGT-LPISYQLLKTSKVLEN---STKN 457
V L P I VI+GQ + + C ++G +P + ++ +L+N + ++
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS 941
Query: 458 SNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGE 517
+ + + EY CVA N + V+ V V+ + Q ILS+ G
Sbjct: 942 DGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVV-VHVLPTIQHGQ-QILSTI---EGI 996
Query: 518 DIVLQCAVNEGSGP-ITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFN 576
+ L C + P + + E + ++ A + + E+ GEY CTA N
Sbjct: 997 PVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG-EESGEYVCTATN 1055
Query: 577 RANHASSVPRSKILTVRV 594
A +A R LTV V
Sbjct: 1056 TAGYAK---RKVQLTVYV 1070
Score = 47.4 bits (111), Expect = 5e-05
Identities = 91/416 (21%), Positives = 153/416 (36%), Gaps = 73/416 (17%)
Query: 69 PQHQMLFYKDDVLFYNISSM---KSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQL 125
P + +YKD+ L +SM + I +I D+G YKC V +N+ T Y L
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKC-VAINSAGATELFYSL 2006
Query: 126 LVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRD 185
V PS + + + VR+ C AP + LK
Sbjct: 2007 QVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP------------SLTWLKDGS---- 2050
Query: 186 QNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPK-----FHI 240
PV L RI++ Q S++ + V V + + ++
Sbjct: 2051 --------PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV 2102
Query: 241 SPTGM-------IMEGAQLHIKCTIQ------VTHLAQEFPEIIIQKDKAIVAHNRHGNK 287
P M ++ + + C +T L P +++K ++ NR K
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHP--LLKKPGLSISENRSVLK 2160
Query: 288 AVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESS--FTHLD--QGERL 343
A V+ +G YTC+ + + VNI + P + S T L +G +
Sbjct: 2161 IED---AQVQDTGRYTCEATNVAGKTEKNYNVNI---WVPPNIGGSDELTQLTVIEGNLI 2214
Query: 344 NLSCSIPGAPPANFTIQKEDTIV------------SQTQDFTKIASKSDSGTYICTA-GI 390
+L C G PP N +K+ + V Q IA KSD+ Y C A +
Sbjct: 2215 SLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNV 2274
Query: 391 DKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLK 446
KK +Q+ + ++ S+ + V +G++I + CE + G P + +K
Sbjct: 2275 AGTAKKEYNLQVYIRPTITNSG-SHPTEIIVTRGKSISLECE-VQGIPPPTVTWMK 2328
Score = 43.5 bits (101), Expect = 7e-04
Identities = 75/323 (23%), Positives = 121/323 (37%), Gaps = 41/323 (12%)
Query: 299 SGNYTCKVESSRISKVSSIVVNITE--LFSKPELESSFTHLDQGERLNLSCSIPGAPPAN 356
+G Y C V S S +S+ + + E + SFT G +++ CS G P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFT---GGSEVSIMCSATGYPKPK 642
Query: 357 FTIQKEDTIV------SQTQD---FTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEM 407
D + T D F K A+ D+G Y C A K N+
Sbjct: 643 IAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNS----TLRY 698
Query: 408 LSQPRIS-YDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDP--AVF 464
+ P++ ++ V G + C++ SG P + K L ST DP +
Sbjct: 699 IEAPKLMVVQSELLVALGDITVMECKT-SGIPPPQVKWFKGDLELRPSTFLIIDPLLGLL 757
Query: 465 KDNPTEDV---EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVL 521
K T+D+ +Y CVA N A + + + V +P V I + +E G ++ L
Sbjct: 758 KIQETQDLDAGDYTCVAIN---EAGRATGKITLDVGSP--PVFIQEPADVSMEIGSNVTL 812
Query: 522 QCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKAS------KEQEGEYYCTAF 575
C V +G T K +R + P + + + + A +G Y C A
Sbjct: 813 PCYV-QGYPEPTIK-WRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA- 869
Query: 576 NRANHASSVPRSKILTVRVILAP 598
N + +TV ++AP
Sbjct: 870 --ENQFGKIQSETTVTVTGLVAP 890
Score = 43.1 bits (100), Expect = 0.001
Identities = 66/343 (19%), Positives = 138/343 (40%), Gaps = 40/343 (11%)
Query: 285 GNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTH-----LDQ 339
G + + +A + Y+C +S ++ + N+ +++ +P + +S +H + +
Sbjct: 2250 GGRQLQISIAEKSDAALYSCV--ASNVAGTAKKEYNL-QVYIRPTITNSGSHPTEIIVTR 2306
Query: 340 GERLNLSCSIPGAPPANFTIQKEDTIVSQTQDF----------TKIASKSDSGTYICTA- 388
G+ ++L C + G PP T K+ + + + K SD+G Y+C A
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAV 2366
Query: 389 GIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLP-ISYQLLKT 447
+ + K + + + S + V++ ++ + CE+ LP I++
Sbjct: 2367 NVAGMTDKKYDLSVHAPPSIIGNHRSPE-NISVVEKNSVSLTCEASGIPLPSITWFKDGW 2425
Query: 448 SKVLENSTKNSNDPAVFK--DNPTEDV-EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQ 504
L NS + + + + ED +Y CV N + ++ + V+ P V
Sbjct: 2426 PVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER---KIFGLSVLVPPHIVG 2482
Query: 505 ISILSSKVVESGEDIVLQCAVNEGSGP-ITYKFYREKEGKPFYQMTSN---ATQAFWTKQ 560
+ L V+ + + L C V P IT+ K+G+P + ++ + F
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQEDEAHHIISGGRFLQIT 2538
Query: 561 KASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGL 603
G Y C A + A H +S+ ++ V ++P G+
Sbjct: 2539 NVQVPHTGRYTCLASSPAGH-----KSRSFSLNVFVSPTIAGV 2576
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/282 (24%), Positives = 103/282 (36%), Gaps = 35/282 (12%)
Query: 285 GNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPEL--ESSFTHLDQGER 342
G + + A + +G YTC ++ K I + + + P + E + +
Sbjct: 2064 GGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV---YVPPNIMGEEQNVSVLISQA 2120
Query: 343 LNLSCSIPGAPPANFT--------IQKEDTIVSQTQDFTKI--ASKSDSGTYICTA-GID 391
+ L C PP T ++K +S+ + KI A D+G Y C A +
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 392 KVVKKSNTVQIVVCEMLSQPRISYD---AQFEVIKGQTIEVRCESISGTLPISYQLLKTS 448
+K+ V I V P I Q VI+G I + CES P K S
Sbjct: 2181 GKTEKNYNVNIWV-----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235
Query: 449 KVLENS------TKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDE 502
VL +S + ++ Y CVA N AK E I P
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK--KEYNLQVYIRPTIT 2293
Query: 503 VQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKP 544
S + +V G+ I L+C V +G P T + K+G P
Sbjct: 2294 NSGSHPTEIIVTRGKSISLECEV-QGIPPPTVTWM--KDGHP 2332
Score = 38.9 bits (89), Expect = 0.017
Identities = 67/307 (21%), Positives = 119/307 (38%), Gaps = 30/307 (9%)
Query: 294 AMVEHSGNYTCKVESSRISKVSSIVVNI-TELFSKPELESSFTHLDQGERLNLSCSIPGA 352
A+ E +G Y C ++ + + I +N+ P L+ +D+ + LSC G
Sbjct: 4048 AVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKP--ITLSCEADGL 4105
Query: 353 PPANFTIQKEDTIVSQTQDFTKIASKS---------DSGTYICTAGIDKVVKKSNTVQIV 403
PP + T K+ + ++ ++S S D+G Y C A V S+T +
Sbjct: 4106 PPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAA--NVAGSSSTSTKL 4163
Query: 404 VCEMLSQPRI-SYDAQFEVIKGQTIEVRCESISGTLP-ISYQL--LKTSKVLENSTKNSN 459
+ PRI S + + V + + C + P I+++ + + +L T
Sbjct: 4164 TVHV--PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPY 4221
Query: 460 DPAVFKDNPTEDVE-YQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGED 518
+ ++ ED Y CVA+N L V V+ E+ + +K GE
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVS-LTVHVLPTFTELPGDVSLNK----GEQ 4276
Query: 519 IVLQCAVNEGSGP-ITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNR 577
+ L C P +T+ F F + ++ ++ SKE G Y CTA N
Sbjct: 4277 LRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVI---ERVSKEDSGTYVCTAENS 4333
Query: 578 ANHASSV 584
++
Sbjct: 4334 VGFVKAI 4340
Score = 36.6 bits (83), Expect = 0.086
Identities = 123/605 (20%), Positives = 217/605 (35%), Gaps = 81/605 (13%)
Query: 47 VQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGT 106
V G+ LTL C + P+ + + +L +++S S I V++ D G
Sbjct: 901 VIEGQQLTLPC---TLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGE 957
Query: 107 YKCTV--IVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFT 164
Y C + KTT+ ++V +P+ + I+G V + C P
Sbjct: 958 YTCVASNVAGTNNKTTS---VVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIW 1014
Query: 165 IEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKS 224
+K EL + D + ++ EE + + +Q + +
Sbjct: 1015 SKKGELIS--TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRP 1072
Query: 225 ELVTVTESFSTPK-FHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVA--- 280
+ S K IS ++ G ++ + C ++ + P I K+ +++
Sbjct: 1073 RVFGDQRGLSQDKPVEIS----VLAGEEVTLPCEVK----SLPPPIITWAKETQLISPFS 1124
Query: 281 --HNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHL- 337
H + ++ SG Y C + + ++ +N+ P+++ HL
Sbjct: 1125 PRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---HVPPKIQRGPKHLK 1181
Query: 338 -DQGERLNLSCSIPGAPPANFTIQKEDTI--------VSQTQDFTKI--ASKSDSGTYIC 386
G+R+++ C+ G P T K + VS I A+ SD+G Y C
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTC 1241
Query: 387 TA----GIDKVVKKSNTVQIVVCEMLSQPRISYDAQF-EVIKGQTIEVRCESISGTLPIS 441
A G D+ + + E L P Y+ F E + Q IE C + GT +
Sbjct: 1242 VATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVANQRIEFPCPA-KGTPKPT 1297
Query: 442 YQLLKTSKVLENSTKNSNDPAVFKDN---------PTEDVEYQCVADNCHSHAKMLSEVL 492
+ L + L T ++ +D P ++ EY CVA N A
Sbjct: 1298 IKWLHNGREL---TGREPGISILEDGTLLVIASVTPYDNGEYICVAVN---EAGTTERKY 1351
Query: 493 RVKVIAPV---DEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMT 549
+KV P D+ Q++ +S V + L C V PI + K Q+T
Sbjct: 1352 NLKVHVPPVIKDKEQVTNVS---VLLNQLTNLFCEVEGTPSPIIMWY------KDNVQVT 1402
Query: 550 SNATQAFWTKQK------ASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGL 603
++T K A+ E G Y C A N A + +L I+
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 604 IAVVI 608
++VV+
Sbjct: 1463 VSVVL 1467
Score = 35.8 bits (81), Expect = 0.15
Identities = 61/298 (20%), Positives = 114/298 (38%), Gaps = 25/298 (8%)
Query: 300 GNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTI 359
G Y C SS + + +++E ++ ++ T + GER L+C I A N T
Sbjct: 495 GFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLTW 553
Query: 360 QKEDTIVSQTQDF-----------TKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEML 408
Q+ D V + K +D+G Y C + ++ V +
Sbjct: 554 QRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSE----GGSSAASVFLTVQ 609
Query: 409 SQPRISYDAQFEVIK-GQTIEVRCESISGTLP-ISYQLLKTSKVLENSTKNSNDPAVFKD 466
P+++ + + G + + C + P I++ + V + + ++D +F
Sbjct: 610 EPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIK 669
Query: 467 N--PTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCA 524
N P + Y C+A N K S + ++ AP V + S +V G+ V++C
Sbjct: 670 NAAPKDAGIYGCLASNSAGTDKQNSTLRYIE--APKLMV---VQSELLVALGDITVMECK 724
Query: 525 VNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHAS 582
+ P F + E +P + + Q+ G+Y C A N A A+
Sbjct: 725 TSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT 782
Score = 33.9 bits (76), Expect = 0.56
Identities = 82/370 (22%), Positives = 145/370 (39%), Gaps = 55/370 (14%)
Query: 272 IQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELE 331
+Q+D+A H G + + V H+G YTC S K S +N+ + +
Sbjct: 2520 LQEDEA--HHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG 2577
Query: 332 SSFTHLDQGERLN----LSCSIPGAPPANFTIQKEDTIVSQTQDFTKI----------AS 377
S D LN L C PPA T K+ T + ++ + A
Sbjct: 2578 SDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ 2637
Query: 378 KSDSGTYICTAGIDK-VVKKSNTVQIVVCEMLSQ-----PRISYDAQFEVIKGQTIEVRC 431
+ ++G Y C A + + K V++ + ++++ P +S + ++ T+ + C
Sbjct: 2638 EDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS-PKEVKIKVNNTLTLEC 2696
Query: 432 ESIS-GTLPISY----QLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAK 486
E+ + + +S+ Q LK+ + N N + + + ++ Y CVA N +
Sbjct: 2697 EAYAIPSASLSWYKDGQPLKSDDHV-NIAANGHTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Query: 487 MLSEVLRVKVIAPVDEV-QISIL-------SSKVVESGEDIVLQCAVNEGSGPITYKFYR 538
+ +V ++V ++ +I + +K V I L C N + P T +Y
Sbjct: 2756 LDFDV-NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETN-AAPPPTLTWY- 2812
Query: 539 EKEGKPFYQMTSNATQAFWTK------QKASKEQEGEYYCTAFNRANHASSVPRSKILTV 592
K+G P +TS+ +A E G Y C A N A S V
Sbjct: 2813 -KDGHP---LTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ-----YDV 2863
Query: 593 RVILAPWKKG 602
RV++ P KG
Sbjct: 2864 RVLVPPIIKG 2873
Score = 32.7 bits (73), Expect = 1.2
Identities = 88/379 (23%), Positives = 134/379 (35%), Gaps = 68/379 (17%)
Query: 268 PEIIIQKDKAIVAHNRHGNKAVYSVM---------AMVEHSGNYTCKVESSRISKVSSIV 318
P I +KD A++A GN A YS++ A V +G Y C ++ + I
Sbjct: 3742 PRITWRKDGAVLA----GNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRID 3797
Query: 319 VNITELFSKPELESSFTHLDQ--GERLNLSCSIPGAPPANFTIQKEDTI--VSQTQDFTK 374
+ + P + T++ + L+C G P + +K + V Q Q+ +
Sbjct: 3798 LQV---HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 375 IASKS----------DSGTYICT----AGIDKVVKKSNTVQIVVCEMLSQPRISYD-AQF 419
+ S D+ TY CT AG DK TV + V P I+ + F
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDK-----RTVDLTV---QVPPSIADEPTDF 3906
Query: 420 EVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK----NSNDPAVFKDNPTEDVEYQ 475
V K + C + P + ++L +S + Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 476 CVADNC--HSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGP-I 532
CVA N +H + V VI P IL++ I+L C P I
Sbjct: 3967 CVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNP-------ILLPCEATGTPSPFI 4019
Query: 533 TYKFYREKEGKPFYQMTSNATQAFWTK-----QKASKEQEGEYYCTAFNRANHASSVPRS 587
T+ +KEG TS A +A +E G Y C A N A A +
Sbjct: 4020 TW----QKEG--INVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKL 4073
Query: 588 KILTVRVILAPWKKGLIAV 606
+ VI K+ +IAV
Sbjct: 4074 NVQVPPVISPHLKEYVIAV 4092
Score = 32.0 bits (71), Expect = 2.1
Identities = 113/562 (20%), Positives = 194/562 (34%), Gaps = 64/562 (11%)
Query: 69 PQHQMLFYKDDVLFYNISS---MKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQL 125
P + +YKD + S + + IP ++ DS TY C V TAE
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVA---NVAGTAEKSF 1631
Query: 126 LVEGVPSPRV-----TLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKRE 180
V+ P + T K+ + + + C +PI L + V +K
Sbjct: 1632 HVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPI------LTWLKDGVPVKAN 1685
Query: 181 KNSR-DQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFH 239
N R + LE ++ + C A ++G + + E +
Sbjct: 1686 DNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG-EKEIKYEVDVLVPPAIEGGDETSYF 1744
Query: 240 ISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHS 299
I ++E H+ + T + + ++I ++D + N G K V + A V ++
Sbjct: 1745 IVMVNNLLE-LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN--GRKLVIA-QAQVSNT 1800
Query: 300 GNYTCKVESSR--ISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANF 357
G Y C ++ K + V++ L + + + + L C G P +
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERV--VVKYKPVALQCIANGIPNPSI 1858
Query: 358 TIQKEDTIVSQTQDFTKIASK-----------SDSGTYICTAGIDKVVKKSNTVQIVVCE 406
T K+D V+ Q KI S D+G Y C A + + +Q+ V E
Sbjct: 1859 TWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVA-TNAAGETQQHIQLHVHE 1917
Query: 407 MLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK----NSNDPA 462
S V+ +++ C++ +P+ K +++L ST N
Sbjct: 1918 PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPV-ITWYKDNRLLSGSTSMTFLNRGQII 1976
Query: 463 VFKDNPTEDVE-YQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVL 521
+ D Y+CVA N + A L L+V V + + V + L
Sbjct: 1977 DIESAQISDAGIYKCVAIN-SAGATELFYSLQVHVAPSISGSNNMV----AVVVNNPVRL 2031
Query: 522 QCAVNEGSGPITYKFYREKEGKPFYQMTSNATQA-----FWTKQKASKEQEGEYYCTAFN 576
+C E G K+G P SN Q A G Y C A N
Sbjct: 2032 EC---EARGIPAPSLTWLKDGSPVSSF-SNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 577 RANHASSVPRSKILTVRVILAP 598
A + + + +RV + P
Sbjct: 2088 AAGE-----KQRDIDLRVYVPP 2104
Score = 32.0 bits (71), Expect = 2.1
Identities = 65/310 (20%), Positives = 114/310 (36%), Gaps = 38/310 (12%)
Query: 299 SGNYTCKVES--SRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP-PA 355
SGNYTC + + K + + + + E+ S + L GE + L C+ G P P
Sbjct: 3219 SGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVL-LGENVELVCNANGIPTPL 3277
Query: 356 NFTIQKEDTIVSQTQDFTKIASK-----------SDSGTYICTAGIDKVVKKSNTVQIVV 404
++ I S + ++++ SD+G Y C A +I
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA----TNPAGEEDRIFN 3333
Query: 405 CEMLSQPRISYDA----QFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSND 460
+ P I + + + +I + C + +GT P LK L S+
Sbjct: 3334 LNVYVTPTIRGNKDEAEKLMTLVDTSINIECRA-TGTPPPQINWLKNGLPLPLSSHIRLL 3392
Query: 461 PA-----VFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVES 515
A + + ++ Y CVA N A + ++ ++V AP + V
Sbjct: 3393 AAGQVIRIVRAQVSDVAVYTCVASN---RAGVDNKHYNLQVFAPPNMDNSMGTEEITVLK 3449
Query: 516 GEDIVLQCAVNEGSGPITYKFYREKEGKPF---YQMTSNATQAFWTKQKASKEQEGEYYC 572
G + C + +G+ + + R+ G+P +T + KA E G+Y C
Sbjct: 3450 GSSTSMAC-ITDGTPAPSMAWLRD--GQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506
Query: 573 TAFNRANHAS 582
A N A S
Sbjct: 3507 IASNEAGEVS 3516
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 57.4 bits (137), Expect = 5e-08
Identities = 88/387 (22%), Positives = 147/387 (37%), Gaps = 84/387 (21%)
Query: 241 SPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVA----HNRHGNKAVYSVMAMV 296
SPT ++EG L + C + P+ II K + H HG+ M++
Sbjct: 2638 SPT--VVEGQTLDLNCVVA------RQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVA 2689
Query: 297 EHSGNYTCKVESSRISKVSSIVVNITELFSKPE---------LESSFTHLDQGERLNLSC 347
+ SG Y C+ ++ + +SIV++++ P +ESS +H+ +GE L+L+C
Sbjct: 2690 D-SGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC 2748
Query: 348 SIPGAPPANFTIQKE-DTIVSQTQD-----FTKIASKSDSGTYIC---------TAGIDK 392
+PG A T K ++ S Q S +DSG Y+C A +
Sbjct: 2749 VVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV 2808
Query: 393 VVKKSNTVQIVVCEMLSQPRISYD-AQFEVIKGQTIEVRC------------ESISGTLP 439
++ S + + V P I + + V +GQT++++C G LP
Sbjct: 2809 TIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLP 2868
Query: 440 ISYQ----LLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVK 495
+Q LL+ ++V +P + EY C S S ++ ++
Sbjct: 2869 ARHQVHGPLLRLNQV----------------SPADSGEYSCQVTG-SSGTLEASVLVTIE 2911
Query: 496 VIAP--------VDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQ 547
+P + I SS V E G+ + L C V G +Y+ P
Sbjct: 2912 PSSPGPIPAPGLAQPIYIEASSSHVTE-GQTLDLNCVV-PGQAHAQVTWYKRGGSLPARH 2969
Query: 548 MTSNATQAFWTKQKASKEQEGEYYCTA 574
T + S GEY C A
Sbjct: 2970 QTHGSQLRL---HLVSPADSGEYVCRA 2993
Score = 56.2 bits (134), Expect = 1e-07
Identities = 117/543 (21%), Positives = 208/543 (38%), Gaps = 82/543 (15%)
Query: 96 IPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTL--DKKEAIQGGIVRVNCS 153
+P V D Y C ++ + A L V G PRV + ++ + G VR+ C
Sbjct: 1920 LPAVEPTDQAQYLCRAH-SSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCR 1978
Query: 154 VPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISG 213
+ + ++ L + S + L P + C A +G
Sbjct: 1979 AAGVPSAT------ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAG 2032
Query: 214 IHMQTSESTKSELVTVTESFSTPKFHI-SPTGMIMEGAQLHIKCTIQVTHLAQEFPEIII 272
T+++ +V S P I S + + EG L + C + + AQ
Sbjct: 2033 ----TAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQV---TWY 2085
Query: 273 QKDKAIVAHNR-HGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITE-LFSKPE- 329
++ ++ H + HG++ ++ + SG Y C+VE+ K +SI V++ S P
Sbjct: 2086 RRGGSLPPHTQVHGSRLRLPQVSPAD-SGEYVCRVENGSGPKEASITVSVLHGTHSGPSY 2144
Query: 330 -----------LESSFTHLDQGERLNLSCSIPGAPPANFTIQKE-DTIVSQTQDFTKI-- 375
+E S +H+ +G+ L+L+C +PG A T K ++ ++ Q +
Sbjct: 2145 TPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLR 2204
Query: 376 ---ASKSDSGTYIC-TAGIDKVVKKSNTVQI---VVCEMLSQPRISYDAQFEVIKGQTIE 428
+ +DSG Y+C G ++ S V I V+ + RI + V +GQT++
Sbjct: 2205 LHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIE-SSSSTVAEGQTLD 2263
Query: 429 VRC------------ESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQC 476
+ C G+LP +Q ++ S++ +F+ +P + +Y C
Sbjct: 2264 LSCVVAGQAHAQVTWYKRGGSLPARHQ-VRGSRLY-----------IFQASPADAGQYVC 2311
Query: 477 VADNC--HSHAKMLSEVLRVKVIAPVDEVQ---ISILSSKVVESGEDIVLQCAVNEGSGP 531
A N S ++ + P Q I SS+V E G+ + L C V G
Sbjct: 2312 RASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAE-GQTLDLNCVV-PGQSH 2369
Query: 532 ITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILT 591
+++ P T + + +AS GEY C SSVP +
Sbjct: 2370 AQVTWHKRGGSLPVRHQTHGSLLRLY---QASPADSGEYVCRVL-----GSSVPLEASVL 2421
Query: 592 VRV 594
V +
Sbjct: 2422 VTI 2424
Score = 55.5 bits (132), Expect = 2e-07
Identities = 88/388 (22%), Positives = 140/388 (36%), Gaps = 71/388 (18%)
Query: 234 STPKFHISPTG-MIMEGAQLHIKCTIQVTHLAQEFPEIIIQK--DKAIVAHNRHGNKAVY 290
ST I P+ + EG L + C + Q ++ K V H HG+ +
Sbjct: 2339 STQPIRIEPSSSQVAEGQTLDLNCVVP----GQSHAQVTWHKRGGSLPVRHQTHGS-LLR 2393
Query: 291 SVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPEL--------ESSFTHLDQGER 342
A SG Y C+V S + +S++V I S P L ESS + + +G+
Sbjct: 2394 LYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQT 2453
Query: 343 LNLSCSIPGAPPANFTIQKEDTIVSQTQDF------TKIASKSDSGTYICTAGIDKVVKK 396
L+L+C + G A T K + + +DSG Y+C +VV
Sbjct: 2454 LDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVC-----RVVGS 2508
Query: 397 SNTVQIVVCEMLSQ-------PRISYDAQFE-----VIKGQTIEVRCESIS--------- 435
S T + V + Q ++Y + E + G T+++ C S
Sbjct: 2509 SGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWY 2568
Query: 436 ---GTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQC-VADNCHSHAKMLSEV 491
G+LP +Q++ + + T P + EY C V++ S L
Sbjct: 2569 KRGGSLPSRHQIVGSRLRIPQVT------------PADSGEYVCHVSNGAGSRETSLIVT 2616
Query: 492 LRVKVIAPVDEVQISI---LSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQM 548
++ + V V I SS V G+ + L C V I +Y+ P
Sbjct: 2617 IQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAI-ITWYKRGGSLPSRHQ 2675
Query: 549 TSNATQAFWTKQKASKEQEGEYYCTAFN 576
T + + S GEY C A N
Sbjct: 2676 THGSHLRL---HQMSVADSGEYVCRANN 2700
Score = 50.4 bits (119), Expect = 6e-06
Identities = 108/527 (20%), Positives = 196/527 (37%), Gaps = 84/527 (15%)
Query: 96 IPEVRIYDSGTYKCT-VIVNNKEKTTAEYQLLVEG-VPSPRVTLDKKEAI--QGGIVRVN 151
I V++ D+GTY CT + ++ TA + G + +P V++ + G +
Sbjct: 1827 IRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFR 1886
Query: 152 CSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARII 211
CS P T+E + K + + IL P E + C+A
Sbjct: 1887 CSATGSPTP---TLEWTGGPGGQLPAKAQIHGG-----ILRLPAVEPTDQAQYLCRAHSS 1938
Query: 212 SGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEII 271
+G + + V P+ +SP E Q+H T+++ A P
Sbjct: 1939 AGQQV-------ARAVLHVHGGGGPRVQVSP-----ERTQVHAGRTVRLYCRAAGVPSAT 1986
Query: 272 I--QKDKAIVAHNRHGNKAVYSVMAM----VEHSGNYTCKVES---SRISKVSSIVVNIT 322
I +K+ + + + + + +G Y C S + +++ +V++ +
Sbjct: 1987 ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSAS 2046
Query: 323 ELFSKP-ELESSFTHLDQGERLNLSCSIPGAPPANFTIQKE------DTIVSQTQDFTKI 375
+ P ++ESS + +G+ L+L+C + G+ A T + T V ++
Sbjct: 2047 DASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQ 2106
Query: 376 ASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRIS-----------YDAQFEVIKG 424
S +DSG Y+C K+++ V+ S P + + V +G
Sbjct: 2107 VSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEG 2166
Query: 425 QTIEVRC------------ESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDV 472
QT+++ C G+LP +Q + L T P +
Sbjct: 2167 QTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVT------------PADSG 2214
Query: 473 EYQC--VADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSG 530
EY C V + A +L + + P+ V+I SS V E G+ + L C V G
Sbjct: 2215 EYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAE-GQTLDLSCVV-AGQA 2272
Query: 531 PITYKFYREKEGKPF-YQMTSNATQAFWTKQKASKEQEGEYYCTAFN 576
+Y+ P +Q+ + F +AS G+Y C A N
Sbjct: 2273 HAQVTWYKRGGSLPARHQVRGSRLYIF----QASPADAGQYVCRASN 2315
Score = 50.4 bits (119), Expect = 6e-06
Identities = 110/539 (20%), Positives = 199/539 (36%), Gaps = 72/539 (13%)
Query: 96 IPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEG-----VPSP----RVTLDKKEAIQGG 146
IP+V DSG Y C V N + ++G VPS R+ ++G
Sbjct: 2587 IPQVTPADSGEYVCHVS-NGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQ 2645
Query: 147 IVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRC 206
+ +NC V + I + ++ L + + + + V + + C
Sbjct: 2646 TLDLNCVVARQPQAI------ITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYV---C 2696
Query: 207 QAR-----IISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVT 261
+A + + I + S S S + S P S + + EG L + C +
Sbjct: 2697 RANNNIDALEASIVISVSPSAGSPSAPGS---SMPIRIESSSSHVAEGETLDLNCVVPGQ 2753
Query: 262 HLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNI 321
AQ ++ ++ +H++ + SG Y C+V S +S++V I
Sbjct: 2754 AHAQVTWH---KRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI 2810
Query: 322 TELFSKP------------ELESSFTHLDQGERLNLSCSIPGAPPANFTIQKED-TIVSQ 368
S +E S + + +G+ L+L C +PG A T K + ++
Sbjct: 2811 EASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPAR 2870
Query: 369 TQDFTKI-----ASKSDSGTYIC-TAGIDKVVKKSNTVQI-------VVCEMLSQPRISY 415
Q + S +DSG Y C G ++ S V I + L+QP
Sbjct: 2871 HQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIE 2930
Query: 416 DAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLE-NSTKNSNDPAVFKDNPTEDVEY 474
+ V +GQT+++ C + G K L + + + +P + EY
Sbjct: 2931 ASSSHVTEGQTLDLNCV-VPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEY 2989
Query: 475 QCVADNCHSHAKMLSEVLRV--------KVIAPVDEVQISILSSKVVESGEDIVLQCAVN 526
C A + + S + V ++ +PV + S V+ G+D +C ++
Sbjct: 2990 VCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPP---SSTVQQGQDASFKCLIH 3046
Query: 527 EGSGPITYKF-YREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSV 584
+G+ PI+ ++ R +E + ++ N + T G Y C A N A SV
Sbjct: 3047 DGAAPISLEWKTRNQELEDNVHISPNG--SIITIVGTRPSNHGTYRCVASNAYGVAQSV 3103
Score = 46.2 bits (108), Expect = 1e-04
Identities = 50/213 (23%), Positives = 88/213 (41%), Gaps = 16/213 (7%)
Query: 376 ASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRI----SYDAQFEVIKGQTIEVRC 431
A SD+GTY+C A + + V+++V P + +A+ V G T +RC
Sbjct: 3175 AKPSDAGTYVCLAQ-NALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRC 3233
Query: 432 ESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDV-EYQCVADNCHSHAKMLSE 490
+ P + K L + D + +D +Y C A + HA+
Sbjct: 3234 SATGSPAP-TIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE---A 3289
Query: 491 VLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTS 550
+ + V +P + +S V++GE + LQC + G+ P+T+++ R P
Sbjct: 3290 TIILHVESPPYATTVPEHAS--VQAGETVQLQCLAH-GTPPLTFQWSRVGSSLPGRATAR 3346
Query: 551 NATQAFWTKQKASKEQEGEYYCTAFNRANHASS 583
N F ++A+ E G Y C N+ A +
Sbjct: 3347 NELLHF---ERAAPEDSGRYRCRVTNKVGSAEA 3376
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 14/171 (8%)
Query: 283 RHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPEL----ESSFTHLD 338
RH ++ +G Y C + S S + +TE SKP E +
Sbjct: 1725 RHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVR 1784
Query: 339 QGERLNLSCSIPGAPPAN---FTIQKEDTIVSQTQDFTKIAS-----KSDSGTYICT-AG 389
G + C+ PA +T + ++ DF I + SD+GTY+CT +
Sbjct: 1785 PGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSN 1844
Query: 390 IDKVVKKSNTVQIVVCEMLSQPRIS-YDAQFEVIKGQTIEVRCESISGTLP 439
+ + + + T+ + LS P +S + Q V GQ E RC + P
Sbjct: 1845 MFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTP 1895
Score = 34.7 bits (78), Expect = 0.33
Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 16/95 (16%)
Query: 329 ELESSFTHLDQGERLNLSCSIPGAPPANFTIQKED--TIVSQTQD--------FTKIASK 378
E+ + + + QG +L C + G+PP F +ED + S TQ F +
Sbjct: 1680 EVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSV-QP 1738
Query: 379 SDSGTYICTAGIDKVVKKSNT--VQIVVCEMLSQP 411
SD+G YICT + + +SNT +++V E S+P
Sbjct: 1739 SDAGVYICTC---RNLHQSNTSRAELLVTEAPSKP 1770
Score = 32.0 bits (71), Expect = 2.1
Identities = 70/359 (19%), Positives = 134/359 (37%), Gaps = 37/359 (10%)
Query: 43 PDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIY 102
P TVQ G++ + +C P ++ L N+ + I R
Sbjct: 3029 PSSTVQQGQDASFKCLIHDGAA----PISLEWKTRNQELEDNVHISPNGSIITIVGTRPS 3084
Query: 103 DSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQ-GGIVRVNC-SVPEEKAP 160
+ GTY+C V N + L V G P+ V + ++ G V + C S E ++
Sbjct: 3085 NHGTYRC-VASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSS 3143
Query: 161 IHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSE 220
+T ++ KL++ + +L+ + ++ C A+ G +
Sbjct: 3144 ARWT----RISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALG-----TA 3194
Query: 221 STKSELVTVTESFS--TPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAI 278
+ E++ T + + P+ + +E T++ + P I K ++
Sbjct: 3195 QKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHT---ATLRCSATGSPAPTIHWSKLRSP 3251
Query: 279 VA--HNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTH 336
+ H G+ + +A + SG Y C S ++I++++ S P + H
Sbjct: 3252 LPWQHRLEGDTLIIPRVAQ-QDSGQYICNATSPAGHAEATIILHVE---SPPYATTVPEH 3307
Query: 337 --LDQGERLNLSCSIPGAPPANF-------TIQKEDTIVSQTQDFTKIASKSDSGTYIC 386
+ GE + L C G PP F ++ T ++ F + A+ DSG Y C
Sbjct: 3308 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFER-AAPEDSGRYRC 3365
Score = 31.6 bits (70), Expect = 2.8
Identities = 39/170 (22%), Positives = 65/170 (38%), Gaps = 15/170 (8%)
Query: 415 YDAQFEVIKGQTIEVRCESISGTLP-ISYQLLKTSKVLENSTKNSND------PAVFKDN 467
+ A+ V +G + +RC+ +SG+ P Y + + + + T+ + P+V
Sbjct: 1682 HPARSIVPQGGSHSLRCQ-VSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSV---Q 1737
Query: 468 PTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNE 527
P++ Y C N H +E+L + + V + S+ V G D+ C
Sbjct: 1738 PSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKS 1797
Query: 528 GSGPITYKFYREKEGK-PFYQMTSNATQAFWTKQKASKEQEGEYYCTAFN 576
S T + R GK P M N T + G Y CT N
Sbjct: 1798 KSPAYTLVWTRLHNGKLPTRAMDFN---GILTIRNVQLSDAGTYVCTGSN 1844
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 56.6 bits (135), Expect = 8e-08
Identities = 86/403 (21%), Positives = 156/403 (38%), Gaps = 54/403 (13%)
Query: 69 PQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVE 128
P ++++Y+ + S+ IP + D+GTY C VN +AE QL V
Sbjct: 608 PPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRA-VNELGDASAEIQLAVG 666
Query: 129 GVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKL--KREKNSRDQ 186
P L + ++ G + + P T + + ++L R SR
Sbjct: 667 HAPQ-LTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQP 725
Query: 187 NFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHIS-PTGM 245
+ +L F + + C+AR + G ++E + + P+ S PT
Sbjct: 726 DSGVLFFESVAPEDQAPYVCEARNVFG-------KVQAEARLIVTGHAPPQIASSAPTVR 778
Query: 246 IMEGAQLHIKCTIQVTHLAQEFPEIIIQKD-KAIVAHNRHGNKAVYSV---MAMVEHSGN 301
++EG + + C + + PE KD + + +RH +A S+ A+ EH+G
Sbjct: 779 VLEGQPVSLPCIVLA---GRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGR 835
Query: 302 YTCKVESSRISKVSSIVVNITELFSKPELESSFTH--LDQGERLNLSCSIPGAPPANFTI 359
Y+C ++ S+ + + + P + + TH ++G +L C G P T
Sbjct: 836 YSCVATNTAGSQHRDVELVVQ---VPPRIHPTATHHITNEGVPASLPCVASGVPAPTITW 892
Query: 360 QKEDTIVSQTQDFTKIA----------SKSDSGTYICTAGIDKVVKKSNTVQIVVCEML- 408
KE ++ ++ S D+G Y+CTA +NTV EM
Sbjct: 893 TKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTA--------TNTVGFSSQEMRL 944
Query: 409 ---SQPRISYDA--------QFEVIKGQTIEVRCESISGTLPI 440
++PRI + Q G+ + + CE+ P+
Sbjct: 945 SVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPL 987
Score = 48.9 bits (115), Expect = 2e-05
Identities = 63/250 (25%), Positives = 100/250 (40%), Gaps = 28/250 (11%)
Query: 343 LNLSCSIPGAPPANFTIQKEDTIVSQTQDFTKI---------ASKSDSGTYICTAGIDKV 393
L +SCS+ A P +++ + + + + F + ASK++ GTY CTA + +
Sbjct: 327 LLVSCSVHSALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTA-VSRA 385
Query: 394 VKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLEN 453
QIVV + P++ V G+T + C + G P + ++ +VL
Sbjct: 386 GTGRAKAQIVVTD--PPPQLVPAPNVTVSPGETAVLSCR-VLGEAPYNLTWVRDWRVLPA 442
Query: 454 STKNSNDPA-----VFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEV-QISI 507
ST A + PT+ YQCVA N + V R V V E Q+SI
Sbjct: 443 STGRVAQLADLSLEISGIIPTDGGRYQCVASNANG-------VTRASVWLLVREAPQVSI 495
Query: 508 -LSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQ 566
SS+ G ++ + C+ + P + RE + Q Q + E
Sbjct: 496 HTSSQHFSQGVEVKVSCSASGYPTP-HISWSRESQALQEDSRIHVDAQGTLIIQGVAPED 554
Query: 567 EGEYYCTAFN 576
G Y C A N
Sbjct: 555 AGNYSCQATN 564
Score = 47.4 bits (111), Expect = 5e-05
Identities = 108/518 (20%), Positives = 185/518 (35%), Gaps = 62/518 (11%)
Query: 103 DSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAP-I 161
D G Y+C V N T A LLV P + + QG V+V+CS P I
Sbjct: 464 DGGRYQC-VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHI 522
Query: 162 HFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSE- 220
++ E L E + D ++ V +D ++ CQA T+E
Sbjct: 523 SWSRESQALQED------SRIHVDAQGTLIIQGVAPEDAG-NYSCQA---------TNEV 566
Query: 221 STKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKD--KAI 278
T E VT+ + ++ ++ G + + C P +I + + I
Sbjct: 567 GTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEAS----GVPPPRVIWYRGGLEMI 622
Query: 279 VAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLD 338
+A + + A +G YTC+ + + I + + EL T ++
Sbjct: 623 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVT-VE 681
Query: 339 QGERLNLSCSIPGAPPANFTIQKEDTIV------------SQTQD----FTKIASKSDSG 382
G L+C G PP T ++ D S+ D F + + D
Sbjct: 682 LGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQA 741
Query: 383 TYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQ-FEVIKGQTIEVRCESISGTLPIS 441
Y+C A V K ++ + P+I+ A V++GQ + + C ++G
Sbjct: 742 PYVCEAR--NVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPE 799
Query: 442 YQLLKTSKVLENSTKNS--NDPAVFKDNPTEDV--EYQCVADNCHSHAKMLSEVLRVKVI 497
LK + L +++S D ++ D ++ Y CVA N S+ V+++
Sbjct: 800 RHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG-----SQHRDVELV 854
Query: 498 APVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGK----PFYQMTSNAT 553
V + + G L C + P T + +E P Y ++ T
Sbjct: 855 VQVPPRIHPTATHHITNEGVPASLPCVASGVPAP-TITWTKETNALTSRGPHYNVSKEGT 913
Query: 554 QAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILT 591
+ S + G Y CTA N +S R + T
Sbjct: 914 LLI---AQPSAQDAGAYVCTATNTVGFSSQEMRLSVNT 948
Score = 37.4 bits (85), Expect = 0.050
Identities = 77/353 (21%), Positives = 137/353 (38%), Gaps = 41/353 (11%)
Query: 252 LHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRH----GNKAVYSVMAMVEHSGNYTCKVE 307
L + C++ H A F + +++ +A + RH GN + + A G Y C
Sbjct: 327 LLVSCSV---HSALPF-RLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAV 382
Query: 308 SSRISKVSSIVVNITELFSKPEL-ESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTI- 365
S + + + +T+ P+L + + GE LSC + G P N T ++ +
Sbjct: 383 SRAGTGRAKAQIVVTD--PPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVL 440
Query: 366 ------VSQTQDFTKIAS---KSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRIS-Y 415
V+Q D + S +D G Y C A V ++ +V ++V E P++S +
Sbjct: 441 PASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVRE---APQVSIH 496
Query: 416 DAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK---NSNDPAVFKDNPTEDV 472
+ +G ++V C S SG + S+ L+ ++ ++ + + ED
Sbjct: 497 TSSQHFSQGVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDA 555
Query: 473 -EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKV-VESGEDIVLQCAVNEGSG 530
Y C A N + + D +S +++ V V GE+ VL C E SG
Sbjct: 556 GNYSCQATN------EVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVC---EASG 606
Query: 531 PITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASS 583
+ + G ++ A + G Y C A N AS+
Sbjct: 607 VPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASA 659
>gi|18201909 vascular cell adhesion molecule 1 isoform b precursor
[Homo sapiens]
Length = 647
Score = 55.8 bits (133), Expect = 1e-07
Identities = 76/365 (20%), Positives = 145/365 (39%), Gaps = 41/365 (11%)
Query: 43 PDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIY 102
P +Q G ++T+ C S+ P+ +F+ + N+ + + + +R+
Sbjct: 232 PSTKLQEGGSVTMTC----SSEGLPAPE---IFWSKKLDNGNLQHLSGNATLTLIAMRME 284
Query: 103 DSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPE------ 156
DSG Y C VN K E +L+V+ P + G V V+C VP
Sbjct: 285 DSGIYVCEG-VNLIGKNRKEVELIVQAFPRDPEIEMSGGLVNGSSVTVSCKVPSVYPLDR 343
Query: 157 ---EKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARI-IS 212
E +E +E E E S + F+ +E+ + L CQA++ I
Sbjct: 344 LEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPT---IEDTGKALV--CQAKLHID 398
Query: 213 GIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIII 272
+ + + ++ + V + +SP+ ++ EG+ +++ C L+Q FP I
Sbjct: 399 DMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTC------LSQGFPAPKI 452
Query: 273 QKDKAI---VAHNRHGNKAVYSVMAMVEHSGNYTCK--VESSRISKVSSIVVNITELFSK 327
+ + N + + +E SG Y C+ ++ R K +++ +T K
Sbjct: 453 LWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTPKDIK 512
Query: 328 PELESSFTHLDQGERLNLSCSIPGAPPANFTIQKE----DTIVSQTQDFTKI--ASKSDS 381
S + +G+ + +SC+ P ++K+ DT++ I A D+
Sbjct: 513 LTAFPS-ESVKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQLKDA 571
Query: 382 GTYIC 386
G Y C
Sbjct: 572 GVYEC 576
Score = 50.4 bits (119), Expect = 6e-06
Identities = 89/411 (21%), Positives = 151/411 (36%), Gaps = 59/411 (14%)
Query: 218 TSESTKSELVTVTESFSTPK---FHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQK 274
T ES K E E +S PK H+S G + G + +KC++ + EI + K
Sbjct: 98 TCESRKLEKGIQVEIYSFPKDPEIHLS--GPLEAGKPITVKCSVADVYPFDRL-EIDLLK 154
Query: 275 DKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSF 334
++ A + +T +E V ++I E+ S P + +
Sbjct: 155 GDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAV 214
Query: 335 -------------------THLDQGERLNLSCSIPGAP-PANFTIQKEDT----IVSQTQ 370
T L +G + ++CS G P P F +K D +S
Sbjct: 215 KELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSGNA 274
Query: 371 DFTKIASK-SDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEV 429
T IA + DSG Y+C G++ + K V+++V P I ++ G ++ V
Sbjct: 275 TLTLIAMRMEDSGIYVCE-GVNLIGKNRKEVELIVQAFPRDPEIEMSGG--LVNGSSVTV 331
Query: 430 RCE--SISGTLPISYQLLKTSKVLEN----------STKNSNDPAVFKDNPT-EDVEYQC 476
C+ S+ + +LLK +LEN S +N + F PT ED
Sbjct: 332 SCKVPSVYPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTF--IPTIEDTGKAL 389
Query: 477 VA------DNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSG 530
V D+ K + V + + + S ++E G + + C +++G
Sbjct: 390 VCQAKLHIDDMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTC-LSQGFP 448
Query: 531 PITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHA 581
+ R+ ++ NAT T E G Y C N+A +
Sbjct: 449 APKILWSRQLPNGELQPLSENAT---LTLISTKMEDSGVYLCEGINQAGRS 496
>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
Length = 2623
Score = 55.8 bits (133), Expect = 1e-07
Identities = 68/314 (21%), Positives = 127/314 (40%), Gaps = 46/314 (14%)
Query: 300 GNYTCKVESSRISKVSSIVVNITELFSKPELESSF---THLDQGERLNLSCSIPGAP--- 353
G Y C SS S+ +++ + E + P +E++ T ++ G++L L+CS G P
Sbjct: 1913 GTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQ 1972
Query: 354 -----PANFTIQKEDTIVS------QTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQI 402
P+ + ++ + S F ++ DSG Y+C A + + + +
Sbjct: 1973 IMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVA---RNKMGDDLILM 2029
Query: 403 VVCEMLSQPRISYDAQF--EVIKGQTIEVRCESISGTLP-ISYQL-----LKTSKVLENS 454
V L +I + F +V+ G+ +V C++ +P IS+ L + + ++S
Sbjct: 2030 HVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDS 2089
Query: 455 TKNSNDPAVF--------KDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQIS 506
+ +F K E+ +Y C A N +M + + VI ++ S
Sbjct: 2090 GHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEM---KVHLTVITAAPRIRQS 2146
Query: 507 ILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPF----YQMTSNATQAFWTKQKA 562
++K +++G+ VL C V P + + F Y +N + T K
Sbjct: 2147 NKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS---LTINKV 2203
Query: 563 SKEQEGEYYCTAFN 576
GEY C A N
Sbjct: 2204 KLLDSGEYVCVARN 2217
Score = 37.0 bits (84), Expect = 0.066
Identities = 68/332 (20%), Positives = 115/332 (34%), Gaps = 54/332 (16%)
Query: 284 HGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTH---LDQG 340
H N + + S ++ C + V + + + E+ +P + F G
Sbjct: 2293 HKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLG 2352
Query: 341 ERLNLSCSIPGAPP-------------ANFTIQKEDTIVSQTQDFTKIASKSDSGTYICT 387
+ L+CS+ G PP +N + I S ++ D+G Y C
Sbjct: 2353 KSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCA 2412
Query: 388 AGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEV--IKGQTIEVRCES-------ISGTL 438
A K ++V+ E+ +P I A V I G+++ + C S I T+
Sbjct: 2413 AR----NKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTM 2468
Query: 439 PISYQLLKTSKVLENSTKNSNDPAVFKDNPTED-VEYQCVADNCHSHAKMLSEVLRVKVI 497
P Y ++ ++ + N V K+ D Y C A N H + + V ++
Sbjct: 2469 PSGY-VVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLI---TVPVMIV 2524
Query: 498 APVDEVQISILSSKVVESGEDIVLQC-AVNEGSGPITYKFYREKEGKPFYQMTSNAT--- 553
A + S V +G L C A+ IT++ P + + S A+
Sbjct: 2525 AYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEM-------PDHSLLSTASKER 2577
Query: 554 ---------QAFWTKQKASKEQEGEYYCTAFN 576
Q Q G Y CTA N
Sbjct: 2578 THGSEQLHLQGTLVIQNPQTSDSGIYKCTAKN 2609
Score = 33.9 bits (76), Expect = 0.56
Identities = 48/211 (22%), Positives = 82/211 (38%), Gaps = 24/211 (11%)
Query: 380 DSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRI--SYDAQFEVIKGQTIEVRCESISGT 437
D G Y+C+A + ++ + + + + PRI + V G T+E++C +
Sbjct: 1717 DRGQYLCSASN---LFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRP 1773
Query: 438 LPISYQLLKTSKVLENSTKNSNDPAVFKDNPT--------EDVEYQCVADNCHSHAKMLS 489
P +L V+ S++ S V D + Y+CVA N +L
Sbjct: 1774 SPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLL- 1832
Query: 490 EVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYRE-KEGKPFYQM 548
++++VIA + V GE + L C P Y + E KP Q
Sbjct: 1833 --VKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPL-QF 1889
Query: 549 TSNATQAF-----WTKQKASKEQEGEYYCTA 574
T++ F + + AS ++ G Y C A
Sbjct: 1890 TNSKLFLFSNGTLYIRNLASSDR-GTYECIA 1919
>gi|146229333 hypothetical protein LOC284021 [Homo sapiens]
Length = 343
Score = 55.8 bits (133), Expect = 1e-07
Identities = 57/227 (25%), Positives = 98/227 (43%), Gaps = 22/227 (9%)
Query: 421 VIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVE---YQCV 477
V+KGQ + + C + +L I+Y L + L + +PA+F + TE E Y+C
Sbjct: 46 VMKGQNVSMFCSHKNKSLQITYSLFRRKTHL-GTQDGKGEPAIFNLSITEAHESGPYKCK 104
Query: 478 AD--NCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGED--IVLQCAVNEGSGPIT 533
A +C +++ S + VD V +L+ V+++ D I L C GS PI
Sbjct: 105 AQVTSCSKYSRDFSFTI-------VDPVTSPVLNIMVIQTETDRHITLHCLSVNGSLPIN 157
Query: 534 YKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRA------NHASSVPRS 587
Y F+ + A + K + +E EY C A NR +H ++P +
Sbjct: 158 YTFFENHVAISPAISKYDREPAEFNLTKKNPGEEEEYRCEAKNRLPNYATYSHPVTMPST 217
Query: 588 KILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMP 634
+ L GL+ ++++ ++I + K Y RKA +P
Sbjct: 218 GGDSCPFCLKLLLPGLLLLLVVIILILAFWVLPK-YKTRKAMRNNVP 263
Score = 50.4 bits (119), Expect = 6e-06
Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 21/175 (12%)
Query: 322 TELFSKPELESSFTHLDQGERLNLSCSIPGAP-PANFTIQKEDTIVSQTQDFT------- 373
T F P L+S + +G+ +++ CS +++ + T + TQD
Sbjct: 31 TNEFPSPCLDSKTKVVMKGQNVSMFCSHKNKSLQITYSLFRRKTHLG-TQDGKGEPAIFN 89
Query: 374 -KIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQT---IEV 429
I +SG Y C A + K S + + ++ P ++ VI+ +T I +
Sbjct: 90 LSITEAHESGPYKCKAQVTSCSKYSRDFSFTIVDPVTSPVLN----IMVIQTETDRHITL 145
Query: 430 RCESISGTLPISYQLLKTSKVLENS-TKNSNDPAVF---KDNPTEDVEYQCVADN 480
C S++G+LPI+Y + + + +K +PA F K NP E+ EY+C A N
Sbjct: 146 HCLSVNGSLPINYTFFENHVAISPAISKYDREPAEFNLTKKNPGEEEEYRCEAKN 200
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 55.5 bits (132), Expect = 2e-07
Identities = 73/339 (21%), Positives = 134/339 (39%), Gaps = 34/339 (10%)
Query: 69 PQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVE 128
P ++++Y+ + S+ IP + D+GTY C VN +AE QL V
Sbjct: 725 PPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRA-VNELGDASAEIQLAVG 783
Query: 129 GVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKL--KREKNSRDQ 186
P L + ++ G + + P T + + ++L R SR
Sbjct: 784 HAPQ-LTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQP 842
Query: 187 NFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHIS-PTGM 245
+ +L F + + C+AR + G ++E + + P+ S PT
Sbjct: 843 DSGVLFFESVAPEDQAPYVCEARNVFG-------KVQAEARLIVTGHAPPQIASSAPTVR 895
Query: 246 IMEGAQLHIKCTIQVTHLAQEFPEIIIQKD-KAIVAHNRHGNKAVYSV---MAMVEHSGN 301
++EG + + C + + PE KD + + +RH +A S+ A+ EH+G
Sbjct: 896 VLEGQPVSLPCIVLA---GRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGR 952
Query: 302 YTCKVESSRISKVSSIVVNITELFSKPELESSFTH--LDQGERLNLSCSIPGAPPANFTI 359
Y+C ++ S+ + + + P + + TH ++G +L C G P T
Sbjct: 953 YSCVATNTAGSQHRDVELVVQ---VPPRIHPTATHHITNEGVPASLPCVASGVPAPTITW 1009
Query: 360 QKEDTIVSQTQDFTKIA----------SKSDSGTYICTA 388
KE ++ ++ S D+G Y+CTA
Sbjct: 1010 TKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTA 1048
Score = 51.2 bits (121), Expect = 3e-06
Identities = 114/556 (20%), Positives = 204/556 (36%), Gaps = 75/556 (13%)
Query: 66 HVKPQHQMLFYKDDV---LFYNISSMKSTESYFIPEVRIYDSGTYKCTVI-VNNKEKTTA 121
H P ++ +YKD L + + T + + R+ DSG Y C + +++
Sbjct: 2962 HAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLV 3021
Query: 122 EYQLLVEGV--PSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKR 179
+ +LV +PR D G ++C P T+ + + +V +R
Sbjct: 3022 QLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEP---TVTWYKDGQPLVLAQR 3078
Query: 180 EKNSRD-QNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKF 238
+ R Q I E V ++ + C+ ++G ++T T V V +F PK
Sbjct: 3079 TQALRGGQRLEIQEAQVSDKGL---YSCKVSNVAGEAVRTFTLT----VQVPPTFENPK- 3130
Query: 239 HISPTGMIMEGAQLHIKCTIQ------VTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSV 292
+ T + G+ L + C + VT L P + A+ G + S
Sbjct: 3131 --TETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPV----ESSAVHGVVSRGGRLQLSR 3184
Query: 293 MAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFT----HLDQGERLNLSCS 348
+ + +G YTC E+++ VV + P + SS H+ +G+ + L C
Sbjct: 3185 LQPAQ-AGTYTCVAENTQAEARKDFVVAV---LVAPRIRSSGVAREHHVLEGQEVRLDCE 3240
Query: 349 IPGAPPANFTIQKEDTIVSQTQD------------FTKIASKSDSGTYICT----AGIDK 392
G PP + K+ + + Q K SD+G Y C AG D
Sbjct: 3241 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGED- 3299
Query: 393 VVKKSNTVQIVVCEMLSQPRISYDAQFEVIK--GQTIEVRCESISGTLPISYQLLKTSKV 450
+ +TV ++V + Q D ++ G+ + + C + G+ PI LK
Sbjct: 3300 --ARLHTVNVLVPPTIKQ---GADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLP 3353
Query: 451 LENSTK-----NSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQI 505
L S + + + + K + + CVA S A + ++V P +
Sbjct: 3354 LPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA---ASPAGVADRNFTLQVQVPPVLEPV 3410
Query: 506 SILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKE 565
+ VV G + L C P+ K+G+P + + + + +
Sbjct: 3411 EFQNDVVVVRGSLVELPCEARGVPLPLVSWM---KDGEPLLSQSLEQGPSLQLEAVGAGD 3467
Query: 566 QEGEYYCTAFNRANHA 581
G Y C A + A A
Sbjct: 3468 -SGTYSCVAVSEAGEA 3482
Score = 48.9 bits (115), Expect = 2e-05
Identities = 63/250 (25%), Positives = 100/250 (40%), Gaps = 28/250 (11%)
Query: 343 LNLSCSIPGAPPANFTIQKEDTIVSQTQDFTKI---------ASKSDSGTYICTAGIDKV 393
L +SCS+ A P +++ + + + + F + ASK++ GTY CTA + +
Sbjct: 444 LLVSCSVHSALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTA-VSRA 502
Query: 394 VKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLEN 453
QIVV + P++ V G+T + C + G P + ++ +VL
Sbjct: 503 GTGRAKAQIVVTD--PPPQLVPAPNVTVSPGETAVLSCR-VLGEAPYNLTWVRDWRVLPA 559
Query: 454 STKNSNDPA-----VFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEV-QISI 507
ST A + PT+ YQCVA N + V R V V E Q+SI
Sbjct: 560 STGRVAQLADLSLEISGIIPTDGGRYQCVASNANG-------VTRASVWLLVREAPQVSI 612
Query: 508 -LSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQ 566
SS+ G ++ + C+ + P + RE + Q Q + E
Sbjct: 613 HTSSQHFSQGVEVKVSCSASGYPTP-HISWSRESQALQEDSRIHVDAQGTLIIQGVAPED 671
Query: 567 EGEYYCTAFN 576
G Y C A N
Sbjct: 672 AGNYSCQATN 681
Score = 47.4 bits (111), Expect = 5e-05
Identities = 108/528 (20%), Positives = 189/528 (35%), Gaps = 62/528 (11%)
Query: 103 DSGTYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAP-I 161
D G Y+C V N T A LLV P + + QG V+V+CS P I
Sbjct: 581 DGGRYQC-VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHI 639
Query: 162 HFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSE- 220
++ E L E + D ++ V +D ++ CQA T+E
Sbjct: 640 SWSRESQALQED------SRIHVDAQGTLIIQGVAPEDAG-NYSCQA---------TNEV 683
Query: 221 STKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKD--KAI 278
T E VT+ + ++ ++ G + + C P +I + + I
Sbjct: 684 GTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEAS----GVPPPRVIWYRGGLEMI 739
Query: 279 VAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLD 338
+A + + A +G YTC+ + + I + + EL T ++
Sbjct: 740 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVT-VE 798
Query: 339 QGERLNLSCSIPGAPPANFTIQKEDTIV------------SQTQD----FTKIASKSDSG 382
G L+C G PP T ++ D S+ D F + + D
Sbjct: 799 LGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQA 858
Query: 383 TYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQ-FEVIKGQTIEVRCESISGTLPIS 441
Y+C A V K ++ + P+I+ A V++GQ + + C ++G
Sbjct: 859 PYVCEAR--NVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPE 916
Query: 442 YQLLKTSKVLENSTKNS--NDPAVFKDNPTEDV--EYQCVADNCHSHAKMLSEVLRVKVI 497
LK + L +++S D ++ D ++ Y CVA N S+ V+++
Sbjct: 917 RHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG-----SQHRDVELV 971
Query: 498 APVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGK----PFYQMTSNAT 553
V + + G L C + P T + +E P Y ++ T
Sbjct: 972 VQVPPRIHPTATHHITNEGVPASLPCVASGVPAP-TITWTKETNALTSRGPHYNVSKEGT 1030
Query: 554 QAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKK 601
+ S + G Y CTA N +S R + + + W++
Sbjct: 1031 LLI---AQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEE 1075
Score = 47.0 bits (110), Expect = 6e-05
Identities = 71/306 (23%), Positives = 130/306 (42%), Gaps = 36/306 (11%)
Query: 297 EHSGNYTCKVESS--RISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPP 354
+ +G YTC E++ R + + + + +F+ + S L G+RL L C+ G+P
Sbjct: 4101 QDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRS---LRLGDRLWLRCAARGSPT 4157
Query: 355 ANFTIQKEDTIVSQ---TQDFTKI-----ASKSDSGTYICTAGIDKVVKKSNTVQIVVCE 406
D V++ QD S+ DSGTY+C A + V ++ V V
Sbjct: 4158 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWA--ENRVGRTQAVSFV--H 4213
Query: 407 MLSQPRISYDAQFEVIK--GQTIEVRCESISGTLP----ISYQLLKTSKVLENSTKNSND 460
+ P + +A +++ G +I++ C +P I L L + +N +
Sbjct: 4214 VKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGS- 4272
Query: 461 PAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIV 520
+ + + YQC+A+N AK + V+ V APV +V+ ++ V SG+D+
Sbjct: 4273 LTIHRTERDDAGRYQCLAENEMGVAKKV--VILVLQSAPVFQVEPQDMT---VRSGDDVA 4327
Query: 521 LQCAVNEGSGPITYKFYREKEGKPF---YQMTSNATQAFWTKQKASKEQEGEYYCTAFNR 577
L+C + +G T + G+P ++ + + W + G Y C A N
Sbjct: 4328 LRC---QATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWL-ENVETGDAGTYDCVAHNL 4383
Query: 578 ANHASS 583
A++
Sbjct: 4384 LGSATA 4389
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/266 (23%), Positives = 101/266 (37%), Gaps = 19/266 (7%)
Query: 339 QGERLNLSCSIPGAP-PANFTIQKEDTIVSQTQDF-----TKIASKSDSGTYICTAGIDK 392
+G + L C G P P ++ + ++SQ+ + + DSGTY C A + +
Sbjct: 3420 RGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA-VSE 3478
Query: 393 VVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLE 452
+ Q+ V E + + G +E+ C++ GT + K + L
Sbjct: 3479 AGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDA-QGTPQPNITWHKDGQALT 3537
Query: 453 NSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKV 512
NS V + Y C+A+ S A + + RV+V AP + V V
Sbjct: 3538 RLENNSRATRVLRVRDAG--LYTCLAE---SPAGAIEKSFRVRVQAPPNIVGPRGPRFVV 3592
Query: 513 VESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQA---FWTKQKASKEQEGE 569
+ +VL+C+V P K ++G + F Q S G+
Sbjct: 3593 GLAPGQLVLECSVEAEPAP---KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGD 3649
Query: 570 YYCTAFNRANHASSVPRSKILTVRVI 595
Y CTA N A S R +I TV I
Sbjct: 3650 YSCTARNAAGSTSVAFRVEIHTVPTI 3675
Score = 42.7 bits (99), Expect = 0.001
Identities = 70/309 (22%), Positives = 112/309 (36%), Gaps = 33/309 (10%)
Query: 294 AMVEHSGNYTCKVESSRISKVSS--IVVNITELFSK--PELESSFTHLDQGERLNLSCSI 349
A E +GNY C ++S S + +VV + + P+L ++ +G L C
Sbjct: 4007 ASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTT-----EGSHAFLPCKA 4061
Query: 350 PGAPPANFTIQKEDTIVSQTQD----------FTKIASKSDSGTYICTAGIDKVVKKSNT 399
G+P N T K+ VS + K D+GTY CTA + V +
Sbjct: 4062 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAE-NAVGRARRR 4120
Query: 400 VQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSN 459
V + + + + D + G + +RC + P + V E ++
Sbjct: 4121 VHLTILVLPVFTTLPGDRSLRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDG 4178
Query: 460 DPAVFKD--NPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGE 517
+ + + + Y C A+N + +S V VK APV +Q S V G
Sbjct: 4179 GSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFV-HVKE-APV--LQGEAFSYLVEPVGG 4234
Query: 518 DIVLQCAVNEGSGPITYKFYREKEGKPF--YQMTSNATQAFWTKQKASKEQEGEYYCTAF 575
I L C V P + K+G P + T + ++ G Y C A
Sbjct: 4235 SIQLDCVVRGDPVP---DIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAE 4291
Query: 576 NRANHASSV 584
N A V
Sbjct: 4292 NEMGVAKKV 4300
Score = 37.4 bits (85), Expect = 0.050
Identities = 77/353 (21%), Positives = 137/353 (38%), Gaps = 41/353 (11%)
Query: 252 LHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRH----GNKAVYSVMAMVEHSGNYTCKVE 307
L + C++ H A F + +++ +A + RH GN + + A G Y C
Sbjct: 444 LLVSCSV---HSALPF-RLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAV 499
Query: 308 SSRISKVSSIVVNITELFSKPEL-ESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTI- 365
S + + + +T+ P+L + + GE LSC + G P N T ++ +
Sbjct: 500 SRAGTGRAKAQIVVTD--PPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVL 557
Query: 366 ------VSQTQDFTKIAS---KSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRIS-Y 415
V+Q D + S +D G Y C A V ++ +V ++V E P++S +
Sbjct: 558 PASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVRE---APQVSIH 613
Query: 416 DAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK---NSNDPAVFKDNPTEDV 472
+ +G ++V C S SG + S+ L+ ++ ++ + + ED
Sbjct: 614 TSSQHFSQGVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDA 672
Query: 473 -EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKV-VESGEDIVLQCAVNEGSG 530
Y C A N + + D +S +++ V V GE+ VL C E SG
Sbjct: 673 GNYSCQATN------EVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVC---EASG 723
Query: 531 PITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASS 583
+ + G ++ A + G Y C A N AS+
Sbjct: 724 VPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASA 776
Score = 33.1 bits (74), Expect = 0.95
Identities = 66/306 (21%), Positives = 110/306 (35%), Gaps = 28/306 (9%)
Query: 294 AMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP 353
A+ H+G YTC +S + + + L S + + E L L C G P
Sbjct: 3917 ALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL-LPCEASGIP 3975
Query: 354 PANFTIQKEDTIVSQTQDFTKI----------ASKSDSGTYICTAGIDKVVKKSNTVQIV 403
T QKE V+ T T++ AS D+G Y+C A T +V
Sbjct: 3976 RPTITWQKEGLNVA-TGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 4034
Query: 404 VCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLP-ISYQL--LKTSKVLENSTKNSND 460
+ + + +G + C++ P I++ S T +
Sbjct: 4035 QVPPVIENGL---PDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG 4091
Query: 461 PAVFKDNPTEDV-EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDI 519
+ K+ +D Y C A+N A+ RV + V V ++ + + G+ +
Sbjct: 4092 ELLVKNLEGQDAGTYTCTAENAVGRARR-----RVHLTILVLPVFTTLPGDRSLRLGDRL 4146
Query: 520 VLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKA-SKEQEGEYYCTAFNRA 578
L+CA G T + +P + S ++ A S+E G Y C A NR
Sbjct: 4147 WLRCAAR---GSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRV 4203
Query: 579 NHASSV 584
+V
Sbjct: 4204 GRTQAV 4209
Score = 31.2 bits (69), Expect = 3.6
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 11/122 (9%)
Query: 299 SGNYTCKVESSRISKVSSIVVNITELFSKPELESSFT----HLDQGERLNLSCSIPGAPP 354
SG Y+C S + + E P +E S L G + L C G P
Sbjct: 3468 SGTYSCVAVSEAGEARRHFQLTVME---PPHIEDSGQPTELSLTPGAPMELLCDAQGTPQ 3524
Query: 355 ANFTIQKEDTIVSQTQD---FTKIASKSDSGTYICTAGIDK-VVKKSNTVQIVVCEMLSQ 410
N T K+ +++ ++ T++ D+G Y C A ++KS V++ +
Sbjct: 3525 PNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG 3584
Query: 411 PR 412
PR
Sbjct: 3585 PR 3586
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/265 (21%), Positives = 113/265 (42%), Gaps = 15/265 (5%)
Query: 375 IASKSDSGTYICTAGIDKVVKKSNTVQIVV------CEMLSQPRISYDAQFEVIKGQTIE 428
I + DSGTY C A + ++S+ + + V E+ + ++ EV++G ++
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
Query: 429 VRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKML 488
E+ S P +Y +L ++T+ AV +++ + Y+C+ N +H L
Sbjct: 187 FLAETKSHP-PCAYTWFLLDSILSHTTRTFTIHAVSREH---EGLYRCLVSNSATHLSSL 242
Query: 489 SEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQM 548
L+V+V+ + Q+ S +VE+ + L C S + + F + P +
Sbjct: 243 G-TLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQW-FLSGQPLLPSEHL 300
Query: 549 TSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAP-WKKGLIAVV 607
+A + G Y C +N + A S P LT+ + G IA +
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE--LTINCPQSSSLSSGAIAGI 358
Query: 608 IIGVIIALLIIAAKCYFLRKAKAKQ 632
+IG++ + + + YFL A++
Sbjct: 359 VIGILAVIAVASELGYFLYIRNARR 383
Score = 43.9 bits (102), Expect = 5e-04
Identities = 74/356 (20%), Positives = 142/356 (39%), Gaps = 34/356 (9%)
Query: 230 TESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNR----HG 285
+ + P +SP I + + CT + ++ + + + ++V H R
Sbjct: 64 SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHW----VSNNLSVVFHERMQLSKD 119
Query: 286 NKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKP---ELESSFT-----HL 337
K + ++ E SG Y C+ + +S+ S + + P +LES +
Sbjct: 120 GKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEV 179
Query: 338 DQGERLNLSCSIPGAPPANFTIQKEDTIVSQT-QDFTKIA-SKSDSGTYICTAGIDKVVK 395
+G + PP +T D+I+S T + FT A S+ G Y C
Sbjct: 180 MEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
Query: 396 KS-NTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISY----QLLKTSKV 450
S T+++ V E L+ P++ + V +++++ C++++ ++ + + Q L S+
Sbjct: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
Query: 451 LENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSS 510
L+ S N + + Y C N S A+ SE L + + P Q S LSS
Sbjct: 300 LQLSADN-RTLIIHGLQRNDTGPYACEVWNWGSRAR--SEPLELTINCP----QSSSLSS 352
Query: 511 KVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQ 566
+ ++ AV + + Y Y +P + T + + T Q KE+
Sbjct: 353 GAIAG--IVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHE--TSQPIPKEE 404
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/265 (21%), Positives = 113/265 (42%), Gaps = 15/265 (5%)
Query: 375 IASKSDSGTYICTAGIDKVVKKSNTVQIVV------CEMLSQPRISYDAQFEVIKGQTIE 428
I + DSGTY C A + ++S+ + + V E+ + ++ EV++G ++
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
Query: 429 VRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKML 488
E+ S P +Y +L ++T+ AV +++ + Y+C+ N +H L
Sbjct: 187 FLAETKSHP-PCAYTWFLLDSILSHTTRTFTIHAVSREH---EGLYRCLVSNSATHLSSL 242
Query: 489 SEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQM 548
L+V+V+ + Q+ S +VE+ + L C S + + F + P +
Sbjct: 243 G-TLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQW-FLSGQPLLPSEHL 300
Query: 549 TSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAP-WKKGLIAVV 607
+A + G Y C +N + A S P LT+ + G IA +
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE--LTINCPQSSSLSSGAIAGI 358
Query: 608 IIGVIIALLIIAAKCYFLRKAKAKQ 632
+IG++ + + + YFL A++
Sbjct: 359 VIGILAVIAVASELGYFLYIRNARR 383
Score = 43.9 bits (102), Expect = 5e-04
Identities = 74/356 (20%), Positives = 142/356 (39%), Gaps = 34/356 (9%)
Query: 230 TESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNR----HG 285
+ + P +SP I + + CT + ++ + + + ++V H R
Sbjct: 64 SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHW----VSNNLSVVFHERMQLSKD 119
Query: 286 NKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKP---ELESSFT-----HL 337
K + ++ E SG Y C+ + +S+ S + + P +LES +
Sbjct: 120 GKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEV 179
Query: 338 DQGERLNLSCSIPGAPPANFTIQKEDTIVSQT-QDFTKIA-SKSDSGTYICTAGIDKVVK 395
+G + PP +T D+I+S T + FT A S+ G Y C
Sbjct: 180 MEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
Query: 396 KS-NTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISY----QLLKTSKV 450
S T+++ V E L+ P++ + V +++++ C++++ ++ + + Q L S+
Sbjct: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
Query: 451 LENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSS 510
L+ S N + + Y C N S A+ SE L + + P Q S LSS
Sbjct: 300 LQLSADN-RTLIIHGLQRNDTGPYACEVWNWGSRAR--SEPLELTINCP----QSSSLSS 352
Query: 511 KVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQ 566
+ ++ AV + + Y Y +P + T + + T Q KE+
Sbjct: 353 GAIAG--IVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHE--TSQPIPKEE 404
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 55.1 bits (131), Expect = 2e-07
Identities = 75/325 (23%), Positives = 128/325 (39%), Gaps = 23/325 (7%)
Query: 300 GNYTCKVESS-RISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFT 358
G Y C +++ + +++N+ P + S+T+ G L+LSC PPA ++
Sbjct: 389 GPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYS 448
Query: 359 IQKEDTIVSQTQD-FTKIASKSDSGTYICTAGIDKVVKKSNTVQ-IVVCEMLSQPRISYD 416
+ I TQ+ F ++ +SG Y C A TV+ I V L +P IS +
Sbjct: 449 WLIDGNIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSN 508
Query: 417 AQFEVIKGQTIEVRCESISGTLP----ISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDV 472
V + CE + ++ Q L S L+ S N +F +
Sbjct: 509 NSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGN-RTLTLFNVTRNDAR 567
Query: 473 EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPI 532
Y C N S + S+ + + V+ D IS S + SG ++ L C + S P
Sbjct: 568 AYVCGIQNSVSANR--SDPVTLDVLYGPDTPIISPPDSSYL-SGANLNLSC--HSASNPS 622
Query: 533 TYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTV 592
+R + TQ + K + G Y C N A ++ S + ++
Sbjct: 623 PQYSWR------INGIPQQHTQVLFI-AKITPNNNGTYACFVSNLATGRNN---SIVKSI 672
Query: 593 RVILAPWKKGLIAVVIIGVIIALLI 617
V + GL A +G++I +L+
Sbjct: 673 TVSASGTSPGLSAGATVGIMIGVLV 697
Score = 46.2 bits (108), Expect = 1e-04
Identities = 36/152 (23%), Positives = 66/152 (43%), Gaps = 3/152 (1%)
Query: 284 HGNKAVYSVMAMVEHSGNYTCKVESSRISKVS-SIVVNITELFSKPELESSFTHLDQGER 342
+GN+ + + +Y C+ ++ ++ S S+++N+ P + T GE
Sbjct: 195 NGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGEN 254
Query: 343 LNLSCSIPGAPPANFTIQKEDTIVSQTQD-FTKIASKSDSGTYICTA-GIDKVVKKSNTV 400
LNLSC PPA ++ T TQ+ F + ++SG+Y C A D + ++
Sbjct: 255 LNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVT 314
Query: 401 QIVVCEMLSQPRISYDAQFEVIKGQTIEVRCE 432
I V +P I+ + V + + CE
Sbjct: 315 TITVYAEPPKPFITSNNSNPVEDEDAVALTCE 346
Score = 35.0 bits (79), Expect = 0.25
Identities = 81/409 (19%), Positives = 152/409 (37%), Gaps = 52/409 (12%)
Query: 48 QNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTY 107
++G+NL L C A S+ Q+ F N + +ST+ FIP + + +SG+Y
Sbjct: 250 RSGENLNLSCHA----ASNPPAQYSW--------FVNGTFQQSTQELFIPNITVNNSGSY 297
Query: 108 KCTVIVNNK--EKTTAEYQLLVEGVPSPRVTLDKKEAIQG-GIVRVNCSVPEEKAPIHFT 164
C ++ +TT + P P +T + ++ V + C PE I T
Sbjct: 298 TCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCE-PE----IQNT 352
Query: 165 IEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKS 224
+N + + + + N + V D V + C GI + S S
Sbjct: 353 TYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRND-VGPYEC------GIQNKLSVD-HS 404
Query: 225 ELVTVTESFSTPKFHISPT-GMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNR 283
+ V + + ISP+ G L + C H A P Q I + +
Sbjct: 405 DPVILNVLYGPDDPTISPSYTYYRPGVNLSLSC-----HAASNPP---AQYSWLIDGNIQ 456
Query: 284 HGNKAVYSVMAMVEHSGNYTCKVESSRI--SKVSSIVVNITELFSKPELESSFTH-LDQG 340
+ ++ ++SG YTC+ +S S+ + + ++ KP + S+ + ++
Sbjct: 457 QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDK 516
Query: 341 ERLNLSCSIPGAPPANFT--IQKEDTIVSQTQDFTK--------IASKSDSGTYICTAGI 390
+ + +C P A + + + VS + +++D+ Y+C
Sbjct: 517 DAVAFTCE-PEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQN 575
Query: 391 DKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLP 439
+S+ V + V P IS + G + + C S S P
Sbjct: 576 SVSANRSDPVTLDVLYGPDTPIIS-PPDSSYLSGANLNLSCHSASNPSP 623
>gi|157057547 Fc receptor-like 6 [Homo sapiens]
Length = 434
Score = 54.7 bits (130), Expect = 3e-07
Identities = 76/362 (20%), Positives = 140/362 (38%), Gaps = 33/362 (9%)
Query: 376 ASKSDSGTYICTAGIDKV----VKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRC 431
A+ G Y C+ + + + S T + V E+ P +S E +G + +RC
Sbjct: 73 ATVQSRGQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRC 132
Query: 432 ES----ISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKM 487
++ + L + + K L++ + + + + Y C +
Sbjct: 133 QTKLHPLRSALRLLFSFHKDGHTLQDRGPHP-ELCIPGAKEGDSGLYWCEVAPEGGQVQK 191
Query: 488 LSEVLRVKVIAPVDEVQISILSSKVVESGEDIV-LQCAVNEGSGPITYKFYREKEGKPFY 546
S L V+V APV +++ + D+V L C GS PI Y FY +++ +
Sbjct: 192 QSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNH 251
Query: 547 QMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILT-VRVILAPWKKGLIA 605
T + K S++ G Y C A N + S P+ L +V+ P L+
Sbjct: 252 SAPCGGTTSLLFPVK-SEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVP 310
Query: 606 VVIIGVIIALLIIAAKCYFLRK-AKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYG 664
+ ++ ++I AA ++R KA +P + +P E+ + AN H+
Sbjct: 311 WLPASLLGLMVIAAALLVYVRSWRKAGPLPSQ-----IPPTAPGGEQCP---LYANVHHQ 362
Query: 665 HNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAVPDAV 724
D + + S V T + + + +G+KD+ + +EVR P V
Sbjct: 363 KGKD------------EGVVYSVVHRTSKRSEARSAEFTVGRKDSSIICAEVRCLQPSEV 410
Query: 725 ES 726
S
Sbjct: 411 SS 412
Score = 37.4 bits (85), Expect = 0.050
Identities = 52/239 (21%), Positives = 92/239 (38%), Gaps = 26/239 (10%)
Query: 173 KMVKLKREKNSRDQNFVILEFPVEEQDRVLS---------FRCQARIISGIHMQTSESTK 223
K L + K RD F L F E Q + + C +++ I +++++
Sbjct: 43 KNTPLSQVKFYRDGKF--LHFSKENQTLSMGAATVQSRGQYSCSGQVMY-IPQTFTQTSE 99
Query: 224 SELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNR 283
+ +V V E F P P+ EG+ + ++C ++ L + +R
Sbjct: 100 TAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTKLHPLRSALRLLFSFHKDGHTLQDR 159
Query: 284 HGNKAVYSVMAMVEHSGNYTCKV--ESSRISKVS-SIVVNITELFSKPELESSFTHLDQ- 339
+ + A SG Y C+V E ++ K S + V + S+P L D
Sbjct: 160 GPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLEVRVQAPVSRPVLTLHHGPADPA 219
Query: 340 -GERLNLSCSIP-GAPPANFTIQKEDTIVSQ--------TQDFTKIASKSDSGTYICTA 388
G+ + L C G+PP ++ ++ IV T + S+ D+G Y C A
Sbjct: 220 VGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAPCGGTTSLLFPVKSEQDAGNYSCEA 278
>gi|71274107 melanoma cell adhesion molecule [Homo sapiens]
Length = 646
Score = 52.8 bits (125), Expect = 1e-06
Identities = 95/460 (20%), Positives = 168/460 (36%), Gaps = 104/460 (22%)
Query: 190 ILEFPVEEQDRVLSFRCQA--RIISGIHMQTSESTKSELVTVTESFSTPK--FHISPTGM 245
IL+ + ++D+ F C+ R+ SG HM+ S VTV + T K + P GM
Sbjct: 207 ILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE-----VTVPVFYPTEKVWLEVEPVGM 261
Query: 246 IMEGAQLHIKCTIQVTHLAQEFPEIIIQKD----KAIVAHNRHGNKAVYSVMAMVEHSGN 301
+ EG ++ I+C P I K + + N + A EHSG
Sbjct: 262 LKEGDRVEIRCLAD----GNPPPHFSISKQNPSTREAEEETTNDNGVLVLEPARKEHSGR 317
Query: 302 YTCK-----VESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPAN 356
Y C+ S +S+ ++VN S + + +G L L+C +
Sbjct: 318 YECQGLDLDTMISLLSEPQELLVNYV---SDVRVSPAAPERQEGSSLTLTCEAESSQDLE 374
Query: 357 FTIQKEDT-------IVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLS 409
F +E+T V Q D + A G Y C A + + N Q+V +
Sbjct: 375 FQWLREETGQVLERGPVLQLHDLKREA----GGGYRCVASVPS-IPGLNRTQLVNVAIFG 429
Query: 410 QPRISY-DAQFEVIKGQTIEVRCESISGTLP-ISYQLLKTSKVLENSTKNSNDPAVFKDN 467
P +++ + + V + + + CE+ P IS+ + T +++ DP
Sbjct: 430 PPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGT------ASEQDQDPQ----- 478
Query: 468 PTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNE 527
+V++ ++ +++ +++E+G ++C +
Sbjct: 479 ---------------------------RVLSTLN----VLVTPELLETG----VECTASN 503
Query: 528 GSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRS 587
G T + E SN T T + RAN S
Sbjct: 504 DLGKNTSILFLELVNLTTLTPDSNTTTGLSTST-----------ASPHTRANSTS----- 547
Query: 588 KILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRK 627
T R + P +G++ V +I I+ L ++ A YFL K
Sbjct: 548 ---TERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYK 584
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 52.4 bits (124), Expect = 2e-06
Identities = 80/354 (22%), Positives = 139/354 (39%), Gaps = 46/354 (12%)
Query: 377 SKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISG 436
+++D+G Y C +S+ V + V P IS + G + + C + S
Sbjct: 206 TRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTY-YRPGANLSLSCYAASN 264
Query: 437 TLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLS-EVLRVK 495
P Y L + + ST+ P + +N Y C A+N + + + + V
Sbjct: 265 P-PAQYSWL-INGTFQQSTQELFIPNITVNNSGS---YTCHANNSVTGCNRTTVKTIIVT 319
Query: 496 VIAPV-DEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQ 554
++PV + QI + V + + L C+ N+ I + F++ + +M +
Sbjct: 320 ELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRW-FFKNQSLPSSERMKLSQGN 378
Query: 555 AFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGL----IAVVIIG 610
+ +E G Y+C FN + S P +L V P + GL IA ++IG
Sbjct: 379 TTLSINPVKREDAGTYWCEVFNPISKNQSDP--IMLNVNYNALPQENGLSPGAIAGIVIG 436
Query: 611 VI--IALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDD 668
V+ +AL+ +A C FL K + S+ +++ H
Sbjct: 437 VVALVALIAVALAC-FLHFGKTGRA-------------SDQRDLTE----------HKPS 472
Query: 669 VRNHAMKPINDNKEPLNSDVQYT----EVQVSSAESHKDLGKKDTETVYSEVRK 718
V NH ND +N +V Y+ E Q + + TE +YSEV+K
Sbjct: 473 VSNHTQDHSNDPPNKMN-EVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKK 525
Score = 47.0 bits (110), Expect = 6e-05
Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 2/128 (1%)
Query: 284 HGNKAVYSVMAMVEHSGNYTCKVESS-RISKVSSIVVNITELFSKPELESSFTHLDQGER 342
+GN+ + + +G Y C++++ ++ + +N+T P + S T+ G
Sbjct: 195 NGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGAN 254
Query: 343 LNLSCSIPGAPPANFTIQKEDTIVSQTQD-FTKIASKSDSGTYICTAGIDKVVKKSNTVQ 401
L+LSC PPA ++ T TQ+ F + ++SG+Y C A TV+
Sbjct: 255 LSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
Query: 402 IVVCEMLS 409
++ LS
Sbjct: 315 TIIVTELS 322
Score = 34.7 bits (78), Expect = 0.33
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 23/156 (14%)
Query: 50 GKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKC 109
G NL+L C+A S+ Q+ L N + +ST+ FIP + + +SG+Y C
Sbjct: 252 GANLSLSCYA----ASNPPAQYSWLI--------NGTFQQSTQELFIPNITVNNSGSYTC 299
Query: 110 TV--IVNNKEKTTAEYQLLVEGVP---SPRVTLDKKEAI-QGGIVRVNCSVPEEKAPIHF 163
V +TT + ++ E P P++ K V + CS + I +
Sbjct: 300 HANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRW 359
Query: 164 TIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQD 199
+ N+ + +R K S+ + + PV+ +D
Sbjct: 360 FFK----NQSLPSSERMKLSQGNTTLSIN-PVKRED 390
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 24/172 (13%)
Query: 514 ESGEDIVLQCAVNEGSGPITYKFYREKEGKPF-YQMTSNATQAFWTKQKASKEQEGEYYC 572
E G D ++C EGS P+ Y++ + + + + T + + + AS E G Y C
Sbjct: 153 EIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSC 212
Query: 573 TAFNRANHASSVPRSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQ 632
T NR +L + V+ K GLIA IIG ++AL +I + RK + ++
Sbjct: 213 TVRNRVGSDQC-----LLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREE 267
Query: 633 M---------------PVEMSRPAVPLLNSNNE---KMSDPNMEANSHYGHN 666
P + A + SN+ MS NME S +N
Sbjct: 268 KYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN 319
Score = 32.7 bits (73), Expect = 1.2
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 379 SDSGTYICTAGIDKVVKKSNT-VQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGT 437
SD GTY C + K +N + +VV S R D E+ G +++CE G+
Sbjct: 113 SDIGTYQCK--VKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI--GSDFKIKCEPKEGS 168
Query: 438 LPISYQLLKTS 448
LP+ Y+ K S
Sbjct: 169 LPLQYEWQKLS 179
Score = 30.0 bits (66), Expect = 8.1
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 26/133 (19%)
Query: 61 VSTTSHVKPQHQMLFYKDDVLF------------YNISSMKSTE-SYFIPEVRIYDSGTY 107
+S + K ++ Y D ++ + + +KS + S + +++ D GTY
Sbjct: 59 ISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTY 118
Query: 108 KCTV-----IVNNKEKTTAEYQLLVEGVPS-PRVTLDKKEAIQGGIVRVNCSVPEEKAPI 161
+C V + N K L+V PS R +D E I G ++ C E P+
Sbjct: 119 QCKVKKAPGVANKK------IHLVVLVKPSGARCYVDGSEEI-GSDFKIKCEPKEGSLPL 171
Query: 162 HFTIEKLELNEKM 174
+ +KL ++KM
Sbjct: 172 QYEWQKLSDSQKM 184
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 52.0 bits (123), Expect = 2e-06
Identities = 72/307 (23%), Positives = 132/307 (42%), Gaps = 43/307 (14%)
Query: 131 PSPRVTL--DKKEAIQGGIVRVNCSVPEEK-APIHFTIEKLELNEKMVKLKREKNSRDQN 187
P P++T+ + + AI+G + CS +P+ F +K +++ + R Q
Sbjct: 497 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 556
Query: 188 FVILEFPVEEQDRVLSFRCQAR---IISGIHMQTSESTKSEL-VTVTESFSTPKFHISPT 243
++E+ + R + F + + +IS H +S S K++L V + SF+ ++
Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISN-HFGSSYSVKAKLTVNMLPSFTKTPMDLT-- 613
Query: 244 GMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKD--------KAIVAHNRHGNKAVYSVMAM 295
I GA ++C V H A P+I QKD + H + + V
Sbjct: 614 --IRAGAMARLECAA-VGHPA---PQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVK 667
Query: 296 VEHSGNYTCKVESSR--ISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP 353
+E G Y+C ++S IS +++ V T F +P L+ + T +GE L C G+P
Sbjct: 668 IEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVT---KGETAVLQCIAGGSP 724
Query: 354 PANFTIQKEDT--IVSQTQDFTK--------IASKSDSGTYIC----TAGIDKVVKKSNT 399
P K+D+ +V++ F + SD+G Y C T G ++ + +
Sbjct: 725 PPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 784
Query: 400 VQIVVCE 406
+ C+
Sbjct: 785 IPTPTCD 791
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 52.0 bits (123), Expect = 2e-06
Identities = 72/307 (23%), Positives = 132/307 (42%), Gaps = 43/307 (14%)
Query: 131 PSPRVTL--DKKEAIQGGIVRVNCSVPEEK-APIHFTIEKLELNEKMVKLKREKNSRDQN 187
P P++T+ + + AI+G + CS +P+ F +K +++ + R Q
Sbjct: 437 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 496
Query: 188 FVILEFPVEEQDRVLSFRCQAR---IISGIHMQTSESTKSEL-VTVTESFSTPKFHISPT 243
++E+ + R + F + + +IS H +S S K++L V + SF+ ++
Sbjct: 497 GEVMEYTTILRLREVEFASEGKYQCVISN-HFGSSYSVKAKLTVNMLPSFTKTPMDLT-- 553
Query: 244 GMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKD--------KAIVAHNRHGNKAVYSVMAM 295
I GA ++C V H A P+I QKD + H + + V
Sbjct: 554 --IRAGAMARLECAA-VGHPA---PQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVK 607
Query: 296 VEHSGNYTCKVESSR--ISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP 353
+E G Y+C ++S IS +++ V T F +P L+ + T +GE L C G+P
Sbjct: 608 IEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVT---KGETAVLQCIAGGSP 664
Query: 354 PANFTIQKEDT--IVSQTQDFTK--------IASKSDSGTYIC----TAGIDKVVKKSNT 399
P K+D+ +V++ F + SD+G Y C T G ++ + +
Sbjct: 665 PPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 724
Query: 400 VQIVVCE 406
+ C+
Sbjct: 725 IPTPTCD 731
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 51.2 bits (121), Expect = 3e-06
Identities = 114/556 (20%), Positives = 204/556 (36%), Gaps = 75/556 (13%)
Query: 66 HVKPQHQMLFYKDDV---LFYNISSMKSTESYFIPEVRIYDSGTYKCTVI-VNNKEKTTA 121
H P ++ +YKD L + + T + + R+ DSG Y C + +++
Sbjct: 1771 HAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLV 1830
Query: 122 EYQLLVEGV--PSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKR 179
+ +LV +PR D G ++C P T+ + + +V +R
Sbjct: 1831 QLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEP---TVTWYKDGQPLVLAQR 1887
Query: 180 EKNSRD-QNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKF 238
+ R Q I E V ++ + C+ ++G ++T T V V +F PK
Sbjct: 1888 TQALRGGQRLEIQEAQVSDKGL---YSCKVSNVAGEAVRTFTLT----VQVPPTFENPK- 1939
Query: 239 HISPTGMIMEGAQLHIKCTIQ------VTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSV 292
+ T + G+ L + C + VT L P + A+ G + S
Sbjct: 1940 --TETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPV----ESSAVHGVVSRGGRLQLSR 1993
Query: 293 MAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFT----HLDQGERLNLSCS 348
+ + +G YTC E+++ VV + P + SS H+ +G+ + L C
Sbjct: 1994 LQPAQ-AGTYTCVAENTQAEARKDFVVAV---LVAPRIRSSGVAREHHVLEGQEVRLDCE 2049
Query: 349 IPGAPPANFTIQKEDTIVSQTQD------------FTKIASKSDSGTYICT----AGIDK 392
G PP + K+ + + Q K SD+G Y C AG D
Sbjct: 2050 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGED- 2108
Query: 393 VVKKSNTVQIVVCEMLSQPRISYDAQFEVIK--GQTIEVRCESISGTLPISYQLLKTSKV 450
+ +TV ++V + Q D ++ G+ + + C + G+ PI LK
Sbjct: 2109 --ARLHTVNVLVPPTIKQ---GADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLP 2162
Query: 451 LENSTK-----NSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQI 505
L S + + + + K + + CVA S A + ++V P +
Sbjct: 2163 LPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA---ASPAGVADRNFTLQVQVPPVLEPV 2219
Query: 506 SILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKE 565
+ VV G + L C P+ K+G+P + + + + +
Sbjct: 2220 EFQNDVVVVRGSLVELPCEARGVPLPLVSWM---KDGEPLLSQSLEQGPSLQLEAVGAGD 2276
Query: 566 QEGEYYCTAFNRANHA 581
G Y C A + A A
Sbjct: 2277 -SGTYSCVAVSEAGEA 2291
Score = 47.0 bits (110), Expect = 6e-05
Identities = 71/306 (23%), Positives = 130/306 (42%), Gaps = 36/306 (11%)
Query: 297 EHSGNYTCKVESS--RISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPP 354
+ +G YTC E++ R + + + + +F+ + S L G+RL L C+ G+P
Sbjct: 2910 QDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRS---LRLGDRLWLRCAARGSPT 2966
Query: 355 ANFTIQKEDTIVSQ---TQDFTKI-----ASKSDSGTYICTAGIDKVVKKSNTVQIVVCE 406
D V++ QD S+ DSGTY+C A + V ++ V V
Sbjct: 2967 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWA--ENRVGRTQAVSFV--H 3022
Query: 407 MLSQPRISYDAQFEVIK--GQTIEVRCESISGTLP----ISYQLLKTSKVLENSTKNSND 460
+ P + +A +++ G +I++ C +P I L L + +N +
Sbjct: 3023 VKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGS- 3081
Query: 461 PAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIV 520
+ + + YQC+A+N AK + V+ V APV +V+ ++ V SG+D+
Sbjct: 3082 LTIHRTERDDAGRYQCLAENEMGVAKKV--VILVLQSAPVFQVEPQDMT---VRSGDDVA 3136
Query: 521 LQCAVNEGSGPITYKFYREKEGKPF---YQMTSNATQAFWTKQKASKEQEGEYYCTAFNR 577
L+C + +G T + G+P ++ + + W + G Y C A N
Sbjct: 3137 LRC---QATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWL-ENVETGDAGTYDCVAHNL 3192
Query: 578 ANHASS 583
A++
Sbjct: 3193 LGSATA 3198
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/266 (23%), Positives = 101/266 (37%), Gaps = 19/266 (7%)
Query: 339 QGERLNLSCSIPGAP-PANFTIQKEDTIVSQTQDF-----TKIASKSDSGTYICTAGIDK 392
+G + L C G P P ++ + ++SQ+ + + DSGTY C A + +
Sbjct: 2229 RGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA-VSE 2287
Query: 393 VVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLE 452
+ Q+ V E + + G +E+ C++ GT + K + L
Sbjct: 2288 AGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDA-QGTPQPNITWHKDGQALT 2346
Query: 453 NSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKV 512
NS V + Y C+A+ S A + + RV+V AP + V V
Sbjct: 2347 RLENNSRATRVLRVRDAG--LYTCLAE---SPAGAIEKSFRVRVQAPPNIVGPRGPRFVV 2401
Query: 513 VESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQA---FWTKQKASKEQEGE 569
+ +VL+C+V P K ++G + F Q S G+
Sbjct: 2402 GLAPGQLVLECSVEAEPAP---KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGD 2458
Query: 570 YYCTAFNRANHASSVPRSKILTVRVI 595
Y CTA N A S R +I TV I
Sbjct: 2459 YSCTARNAAGSTSVAFRVEIHTVPTI 2484
Score = 42.7 bits (99), Expect = 0.001
Identities = 70/309 (22%), Positives = 112/309 (36%), Gaps = 33/309 (10%)
Query: 294 AMVEHSGNYTCKVESSRISKVSS--IVVNITELFSK--PELESSFTHLDQGERLNLSCSI 349
A E +GNY C ++S S + +VV + + P+L ++ +G L C
Sbjct: 2816 ASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTT-----EGSHAFLPCKA 2870
Query: 350 PGAPPANFTIQKEDTIVSQTQD----------FTKIASKSDSGTYICTAGIDKVVKKSNT 399
G+P N T K+ VS + K D+GTY CTA + V +
Sbjct: 2871 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAE-NAVGRARRR 2929
Query: 400 VQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSN 459
V + + + + D + G + +RC + P + V E ++
Sbjct: 2930 VHLTILVLPVFTTLPGDRSLRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDG 2987
Query: 460 DPAVFKD--NPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGE 517
+ + + + Y C A+N + +S V VK APV +Q S V G
Sbjct: 2988 GSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFV-HVKE-APV--LQGEAFSYLVEPVGG 3043
Query: 518 DIVLQCAVNEGSGPITYKFYREKEGKPF--YQMTSNATQAFWTKQKASKEQEGEYYCTAF 575
I L C V P + K+G P + T + ++ G Y C A
Sbjct: 3044 SIQLDCVVRGDPVP---DIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAE 3100
Query: 576 NRANHASSV 584
N A V
Sbjct: 3101 NEMGVAKKV 3109
Score = 33.1 bits (74), Expect = 0.95
Identities = 66/306 (21%), Positives = 110/306 (35%), Gaps = 28/306 (9%)
Query: 294 AMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP 353
A+ H+G YTC +S + + + L S + + E L L C G P
Sbjct: 2726 ALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL-LPCEASGIP 2784
Query: 354 PANFTIQKEDTIVSQTQDFTKI----------ASKSDSGTYICTAGIDKVVKKSNTVQIV 403
T QKE V+ T T++ AS D+G Y+C A T +V
Sbjct: 2785 RPTITWQKEGLNVA-TGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 2843
Query: 404 VCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLP-ISYQL--LKTSKVLENSTKNSND 460
+ + + +G + C++ P I++ S T +
Sbjct: 2844 QVPPVIENGL---PDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG 2900
Query: 461 PAVFKDNPTEDV-EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDI 519
+ K+ +D Y C A+N A+ RV + V V ++ + + G+ +
Sbjct: 2901 ELLVKNLEGQDAGTYTCTAENAVGRARR-----RVHLTILVLPVFTTLPGDRSLRLGDRL 2955
Query: 520 VLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKA-SKEQEGEYYCTAFNRA 578
L+CA G T + +P + S ++ A S+E G Y C A NR
Sbjct: 2956 WLRCAAR---GSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRV 3012
Query: 579 NHASSV 584
+V
Sbjct: 3013 GRTQAV 3018
Score = 31.2 bits (69), Expect = 3.6
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 11/122 (9%)
Query: 299 SGNYTCKVESSRISKVSSIVVNITELFSKPELESSFT----HLDQGERLNLSCSIPGAPP 354
SG Y+C S + + E P +E S L G + L C G P
Sbjct: 2277 SGTYSCVAVSEAGEARRHFQLTVME---PPHIEDSGQPTELSLTPGAPMELLCDAQGTPQ 2333
Query: 355 ANFTIQKEDTIVSQTQD---FTKIASKSDSGTYICTAGIDK-VVKKSNTVQIVVCEMLSQ 410
N T K+ +++ ++ T++ D+G Y C A ++KS V++ +
Sbjct: 2334 PNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG 2393
Query: 411 PR 412
PR
Sbjct: 2394 PR 2395
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 51.2 bits (121), Expect = 3e-06
Identities = 114/556 (20%), Positives = 204/556 (36%), Gaps = 75/556 (13%)
Query: 66 HVKPQHQMLFYKDDV---LFYNISSMKSTESYFIPEVRIYDSGTYKCTVI-VNNKEKTTA 121
H P ++ +YKD L + + T + + R+ DSG Y C + +++
Sbjct: 1680 HAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLV 1739
Query: 122 EYQLLVEGV--PSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKR 179
+ +LV +PR D G ++C P T+ + + +V +R
Sbjct: 1740 QLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEP---TVTWYKDGQPLVLAQR 1796
Query: 180 EKNSRD-QNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKF 238
+ R Q I E V ++ + C+ ++G ++T T V V +F PK
Sbjct: 1797 TQALRGGQRLEIQEAQVSDKGL---YSCKVSNVAGEAVRTFTLT----VQVPPTFENPK- 1848
Query: 239 HISPTGMIMEGAQLHIKCTIQ------VTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSV 292
+ T + G+ L + C + VT L P + A+ G + S
Sbjct: 1849 --TETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPV----ESSAVHGVVSRGGRLQLSR 1902
Query: 293 MAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFT----HLDQGERLNLSCS 348
+ + +G YTC E+++ VV + P + SS H+ +G+ + L C
Sbjct: 1903 LQPAQ-AGTYTCVAENTQAEARKDFVVAV---LVAPRIRSSGVAREHHVLEGQEVRLDCE 1958
Query: 349 IPGAPPANFTIQKEDTIVSQTQD------------FTKIASKSDSGTYICT----AGIDK 392
G PP + K+ + + Q K SD+G Y C AG D
Sbjct: 1959 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGED- 2017
Query: 393 VVKKSNTVQIVVCEMLSQPRISYDAQFEVIK--GQTIEVRCESISGTLPISYQLLKTSKV 450
+ +TV ++V + Q D ++ G+ + + C + G+ PI LK
Sbjct: 2018 --ARLHTVNVLVPPTIKQ---GADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLP 2071
Query: 451 LENSTK-----NSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQI 505
L S + + + + K + + CVA S A + ++V P +
Sbjct: 2072 LPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA---ASPAGVADRNFTLQVQVPPVLEPV 2128
Query: 506 SILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKE 565
+ VV G + L C P+ K+G+P + + + + +
Sbjct: 2129 EFQNDVVVVRGSLVELPCEARGVPLPLVSWM---KDGEPLLSQSLEQGPSLQLEAVGAGD 2185
Query: 566 QEGEYYCTAFNRANHA 581
G Y C A + A A
Sbjct: 2186 -SGTYSCVAVSEAGEA 2200
Score = 47.4 bits (111), Expect = 5e-05
Identities = 72/306 (23%), Positives = 129/306 (42%), Gaps = 36/306 (11%)
Query: 297 EHSGNYTCKVESS--RISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPP 354
+ +G YTC E++ R + + + + +F+ + S L G+RL L C+ G+P
Sbjct: 2819 QDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRS---LRLGDRLWLRCAARGSPT 2875
Query: 355 ANFTIQKEDTIVSQ---TQDFTKI-----ASKSDSGTYICTAGIDKVVKKSNTVQIVVCE 406
D V++ QD S+ DSGTY+C A + V ++ V V
Sbjct: 2876 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWA--ENRVGRTQAVSFV--H 2931
Query: 407 MLSQPRISYDAQFEVIK--GQTIEVRCESISGTLPISYQLLKTSKVLENS---TKNSNDP 461
+ P + +A +++ G +I++ C +P +K L S + N
Sbjct: 2932 VKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVP-DIHWIKDGLPLRGSHLRHQLQNGS 2990
Query: 462 AVFKDNPTEDV-EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIV 520
+ +D YQC+A+N AK + V+ V APV +V+ ++ V SG+D+
Sbjct: 2991 LTIRRTERDDAGRYQCLAENEMGVAKKV--VILVLQSAPVFQVEPQDMT---VRSGDDVA 3045
Query: 521 LQCAVNEGSGPITYKFYREKEGKPF---YQMTSNATQAFWTKQKASKEQEGEYYCTAFNR 577
L+C + +G T + G+P ++ + + W + G Y C A N
Sbjct: 3046 LRC---QATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWL-ENVETGDAGTYDCVAHNL 3101
Query: 578 ANHASS 583
A++
Sbjct: 3102 LGSATA 3107
Score = 43.1 bits (100), Expect = 0.001
Identities = 70/309 (22%), Positives = 113/309 (36%), Gaps = 33/309 (10%)
Query: 294 AMVEHSGNYTCKVESSRISKVSS--IVVNITELFSK--PELESSFTHLDQGERLNLSCSI 349
A E +GNY C ++S S + +VV + + P+L ++ +G L C
Sbjct: 2725 ASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTT-----EGSHAFLPCKA 2779
Query: 350 PGAPPANFTIQKEDTIVSQTQD----------FTKIASKSDSGTYICTAGIDKVVKKSNT 399
G+P N T K+ VS + K D+GTY CTA + V +
Sbjct: 2780 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAE-NAVGRARRR 2838
Query: 400 VQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSN 459
V + + + + D + G + +RC + P + V E ++
Sbjct: 2839 VHLTILVLPVFTTLPGDRSLRL--GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDG 2896
Query: 460 DPAVFKD--NPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGE 517
+ + + + Y C A+N + +S V VK APV +Q S V G
Sbjct: 2897 GSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFV-HVKE-APV--LQGEAFSYLVEPVGG 2952
Query: 518 DIVLQCAVNEGSGPITYKFYREKEGKPF--YQMTSNATQAFWTKQKASKEQEGEYYCTAF 575
I L C V P + K+G P + T ++ ++ G Y C A
Sbjct: 2953 SIQLDCVVRGDPVP---DIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAE 3009
Query: 576 NRANHASSV 584
N A V
Sbjct: 3010 NEMGVAKKV 3018
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/266 (23%), Positives = 101/266 (37%), Gaps = 19/266 (7%)
Query: 339 QGERLNLSCSIPGAP-PANFTIQKEDTIVSQTQDF-----TKIASKSDSGTYICTAGIDK 392
+G + L C G P P ++ + ++SQ+ + + DSGTY C A + +
Sbjct: 2138 RGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA-VSE 2196
Query: 393 VVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLE 452
+ Q+ V E + + G +E+ C++ GT + K + L
Sbjct: 2197 AGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDA-QGTPQPNITWHKDGQALT 2255
Query: 453 NSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKV 512
NS V + Y C+A+ S A + + RV+V AP + V V
Sbjct: 2256 RLENNSRATRVLRVRDAG--LYTCLAE---SPAGAIEKSFRVRVQAPPNIVGPRGPRFVV 2310
Query: 513 VESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQA---FWTKQKASKEQEGE 569
+ +VL+C+V P K ++G + F Q S G+
Sbjct: 2311 GLAPGQLVLECSVEAEPAP---KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGD 2367
Query: 570 YYCTAFNRANHASSVPRSKILTVRVI 595
Y CTA N A S R +I TV I
Sbjct: 2368 YSCTARNAAGSTSVAFRVEIHTVPTI 2393
Score = 33.1 bits (74), Expect = 0.95
Identities = 66/306 (21%), Positives = 110/306 (35%), Gaps = 28/306 (9%)
Query: 294 AMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP 353
A+ H+G YTC +S + + + L S + + E L L C G P
Sbjct: 2635 ALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL-LPCEASGIP 2693
Query: 354 PANFTIQKEDTIVSQTQDFTKI----------ASKSDSGTYICTAGIDKVVKKSNTVQIV 403
T QKE V+ T T++ AS D+G Y+C A T +V
Sbjct: 2694 RPTITWQKEGLNVA-TGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 2752
Query: 404 VCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLP-ISYQL--LKTSKVLENSTKNSND 460
+ + + +G + C++ P I++ S T +
Sbjct: 2753 QVPPVIENGL---PDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG 2809
Query: 461 PAVFKDNPTEDV-EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDI 519
+ K+ +D Y C A+N A+ RV + V V ++ + + G+ +
Sbjct: 2810 ELLVKNLEGQDAGTYTCTAENAVGRARR-----RVHLTILVLPVFTTLPGDRSLRLGDRL 2864
Query: 520 VLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKA-SKEQEGEYYCTAFNRA 578
L+CA G T + +P + S ++ A S+E G Y C A NR
Sbjct: 2865 WLRCAAR---GSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRV 2921
Query: 579 NHASSV 584
+V
Sbjct: 2922 GRTQAV 2927
Score = 31.2 bits (69), Expect = 3.6
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 11/122 (9%)
Query: 299 SGNYTCKVESSRISKVSSIVVNITELFSKPELESSFT----HLDQGERLNLSCSIPGAPP 354
SG Y+C S + + E P +E S L G + L C G P
Sbjct: 2186 SGTYSCVAVSEAGEARRHFQLTVME---PPHIEDSGQPTELSLTPGAPMELLCDAQGTPQ 2242
Query: 355 ANFTIQKEDTIVSQTQD---FTKIASKSDSGTYICTAGIDK-VVKKSNTVQIVVCEMLSQ 410
N T K+ +++ ++ T++ D+G Y C A ++KS V++ +
Sbjct: 2243 PNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG 2302
Query: 411 PR 412
PR
Sbjct: 2303 PR 2304
>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
Length = 373
Score = 50.8 bits (120), Expect = 4e-06
Identities = 51/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 468 PTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNE 527
P+++ Y C N S + S V+ +KV+ + + L ++ E G D+ LQC +
Sbjct: 103 PSDEGRYTCKVKN--SGRYVWSHVI-LKVLVRPSKPKCE-LEGELTE-GSDLTLQCESSS 157
Query: 528 GSGPITYKF--YREKEGK-----PFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANH 580
G+ PI Y + REKEG+ P ++ N Q + G Y CTA N A
Sbjct: 158 GTEPIVYYWQRIREKEGEDERLPPKSRIDYNHPGRV-LLQNLTMSYSGLYQCTAGNEAGK 216
Query: 581 ASSVPRSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRP 640
S V R + V+ I G++A + G++ L+I + L + K K+ E RP
Sbjct: 217 ESCVVRVTVQYVQSI------GMVAGAVTGIVAGALLIFLLVWLLIRRKDKERYEEEERP 270
Score = 33.1 bits (74), Expect = 0.95
Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 18/121 (14%)
Query: 300 GNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSC-SIPGAPPANFT 358
G YTCKV++S S +++ + SKP+ E L +G L L C S G P +
Sbjct: 107 GRYTCKVKNSGRYVWSHVILKVLVRPSKPKCELE-GELTEGSDLTLQCESSSGTEPIVYY 165
Query: 359 IQK------EDTIVSQTQ--DFT-------KIASKSDSGTYICTAGIDKVVKKSNTVQIV 403
Q+ ED + D+ + + S SG Y CTAG ++ K+S V++
Sbjct: 166 WQRIREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAG-NEAGKESCVVRVT 224
Query: 404 V 404
V
Sbjct: 225 V 225
Score = 31.6 bits (70), Expect = 2.8
Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 20/130 (15%)
Query: 379 SDSGTYICTAGIDKVVKKSNTV-QIVVCEMLSQP-RISYDAQFEVIKGQTIEVRCESISG 436
SD G Y C KV V V+ ++L +P + + + E+ +G + ++CES SG
Sbjct: 104 SDEGRYTC-----KVKNSGRYVWSHVILKVLVRPSKPKCELEGELTEGSDLTLQCESSSG 158
Query: 437 TLPISYQLLK-------TSKVLENSTKNSNDPA-VFKDNPTEDVE--YQCVADNCHSHAK 486
T PI Y + ++ S + N P V N T YQC A N A
Sbjct: 159 TEPIVYYWQRIREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGN---EAG 215
Query: 487 MLSEVLRVKV 496
S V+RV V
Sbjct: 216 KESCVVRVTV 225
>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
Length = 428
Score = 50.4 bits (119), Expect = 6e-06
Identities = 90/420 (21%), Positives = 165/420 (39%), Gaps = 53/420 (12%)
Query: 330 LESSFTHLDQGERLNLSCSIPGAPPANFTIQK---EDTIVS----QTQDFTKIAS--KSD 380
L +S +H +G + L+C +P ++ Q DT + +IA+ K D
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKED 80
Query: 381 SGTYICTAG-IDKVVKKSNTVQIVVCEMLSQPRISYDAQ---FEVIKGQTIEVRCESISG 436
+G+Y C A + V +S QI V + +S + Q +V++G + + C G
Sbjct: 81 TGSYWCEAQTMASKVLRSRRSQINV-HRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
Query: 437 TLPISYQLLKTSKVLENSTKNSNDPAVFKDNPT----EDVEYQCVADNCHSHAKMLSEVL 492
T I++ K + L +K + P+ + +Y CVA+N + + S ++
Sbjct: 140 TGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSP--SGLV 197
Query: 493 RVKVIAPVDEVQISILSSKVVESGEDIV-LQCAVNEGSGPITYKFYREKEGKPFYQMTSN 551
+ V PV + + + + + ED++ L C GS PI Y FY E S
Sbjct: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
Query: 552 ATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKG--LIAVVII 609
+F ++E G Y C AN+ RS+ +T+ + + L + VI
Sbjct: 258 GGASF--NLSLTEEHSGNYSC----EANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIE 311
Query: 610 GVIIAL---LIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHN 666
G++ L + CY L++ ++ + R L ++ P
Sbjct: 312 GLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSPT---------- 361
Query: 667 DDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHK-------DLGKKDTETVYSEVRKA 719
++PI +N ++ D Y+ + E + K + +YS +RKA
Sbjct: 362 ----PGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAETLGTHMEDKVSLDIYSRLRKA 417
Score = 40.0 bits (92), Expect = 0.008
Identities = 49/206 (23%), Positives = 86/206 (41%), Gaps = 26/206 (12%)
Query: 297 EHSGNYTC-------KVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSI 349
E +G+Y C KV SR S+++ V + ++ E + + +G+RL L CS+
Sbjct: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADV--SLETQPPGGQVMEGDRLVLICSV 136
Query: 350 P------------GAPPANFTIQKEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKS 397
GA N + + ++ ++ + +SD+ Y C A S
Sbjct: 137 AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYE--IPSVRESDAEQYYCVAENGYGPSPS 194
Query: 398 NTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK 456
V I V +S+P + A + + +E+ CE++ G+ PI Y L + +
Sbjct: 195 GLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSA 254
Query: 457 NSNDPAVFKDNPTED--VEYQCVADN 480
S A F + TE+ Y C A+N
Sbjct: 255 PSGGGASFNLSLTEEHSGNYSCEANN 280
>gi|11225258 myelin associated glycoprotein isoform a precursor
[Homo sapiens]
Length = 626
Score = 50.4 bits (119), Expect = 6e-06
Identities = 86/415 (20%), Positives = 160/415 (38%), Gaps = 75/415 (18%)
Query: 329 ELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQDFTKI-----ASKSDSGT 383
E+ SS ++ G ++L C PP T ++ T++ + + + + ++ G
Sbjct: 244 EMNSSVEAIE-GSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGV 302
Query: 384 YICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPI--- 440
Y C A + + + TV + V +P ++ ++G+T+ + C + S PI
Sbjct: 303 YACLAE-NAYGQDNRTVGLSVMYAPWKPTVN--GTMVAVEGETVSILCSTQSNPDPILTI 359
Query: 441 --SYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIA 498
Q+L T V+ S PAV +P +D EY CVA+N + +
Sbjct: 360 FKEKQILST--VIYESELQLELPAV---SPEDDGEYWCVAENQYGQRATAFNL------- 407
Query: 499 PVDEVQISILSSKVVESGEDIVLQCAVNEGSGP-ITYKFYREKEGKPFYQMTSNATQAFW 557
V+ + +L S + + + C V P + ++ P +T N ++
Sbjct: 408 SVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFEL-------PSRNVTVNESE--- 457
Query: 558 TKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAP--------------WKKGL 603
++ E+ G + A + PR I T R + W K
Sbjct: 458 -REFVYSERSGLVLTSILTLRGQAQAPPRV-ICTARNLYGAKSLELPFQGAHRLMWAK-- 513
Query: 604 IAVVIIGVIIAL-LIIAAKCYFL---RKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEA 659
+ +G ++A ++IA CY RK + P + P+L S++ ++S +
Sbjct: 514 --IGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKY 571
Query: 660 NSHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYS 714
S + R ++ EP D+ Y SH DLGK+ T+ Y+
Sbjct: 572 ESERRLGSERRLLGLRG-----EPPELDLSY---------SHSDLGKRPTKDSYT 612
Score = 36.6 bits (83), Expect = 0.086
Identities = 33/165 (20%), Positives = 65/165 (39%), Gaps = 10/165 (6%)
Query: 413 ISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDV 472
+ ++ E I+G + + C + S P+ ++ VL + S + + P ED
Sbjct: 243 VEMNSSVEAIEGSHVSLLCGADSNPPPL-LTWMRDGTVLREAVAESLLLELEEVTPAEDG 301
Query: 473 EYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPI 532
Y C+A+N + V + + ++ + V GE + + C+ PI
Sbjct: 302 VYACLAENAYGQDNRT-----VGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPI 356
Query: 533 TYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNR 577
++EK+ ++ S E +GEY+C A N+
Sbjct: 357 L-TIFKEKQ---ILSTVIYESELQLELPAVSPEDDGEYWCVAENQ 397
Score = 30.0 bits (66), Expect = 8.1
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query: 300 GNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAPPANFTI 359
G Y C E++ ++ +++ KP + + ++ GE +++ CS P TI
Sbjct: 301 GVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVE-GETVSILCSTQSNPDPILTI 359
Query: 360 QKEDTIV------SQTQDFTKIASKSDSGTYICTA 388
KE I+ S+ Q S D G Y C A
Sbjct: 360 FKEKQILSTVIYESELQLELPAVSPEDDGEYWCVA 394
>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
Length = 429
Score = 50.1 bits (118), Expect = 8e-06
Identities = 75/321 (23%), Positives = 134/321 (41%), Gaps = 32/321 (9%)
Query: 330 LESSFTHLDQGERLNLSCSIPGAPPANFTIQK---EDTIVS----QTQDFTKIAS--KSD 380
L +S +H +G + L+C +P ++ Q DT + +IA+ K D
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKED 80
Query: 381 SGTYICTAG-IDKVVKKSNTVQIVVCEMLSQPRISYDAQ---FEVIKGQTIEVRCESISG 436
+G+Y C A + V +S QI V + +S + Q +V++G + + C G
Sbjct: 81 TGSYWCEAQTMASKVLRSRRSQINV-HRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
Query: 437 TLPISYQLLKTSKVLENSTKNSNDPAVFKDNPT----EDVEYQCVADNCHSHAKMLSEVL 492
T I++ K + L +K + P+ + +Y CVA+N + + S ++
Sbjct: 140 TGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSP--SGLV 197
Query: 493 RVKVIAPVDEVQISILSSKVVESGEDIV-LQCAVNEGSGPITYKFYREKEGKPFYQMTSN 551
+ V PV + + + + + ED++ L C GS PI Y FY E S
Sbjct: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
Query: 552 ATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKG--LIAVVII 609
+F ++E G Y C AN+ RS+ +T+ + + L + VI
Sbjct: 258 GGASF--NLSLTEEHSGNYSC----EANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIE 311
Query: 610 GVIIAL---LIIAAKCYFLRK 627
G++ L + CY L++
Sbjct: 312 GLLSTLGPATVALLFCYGLKR 332
Score = 40.0 bits (92), Expect = 0.008
Identities = 49/206 (23%), Positives = 86/206 (41%), Gaps = 26/206 (12%)
Query: 297 EHSGNYTC-------KVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSI 349
E +G+Y C KV SR S+++ V + ++ E + + +G+RL L CS+
Sbjct: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADV--SLETQPPGGQVMEGDRLVLICSV 136
Query: 350 P------------GAPPANFTIQKEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKS 397
GA N + + ++ ++ + +SD+ Y C A S
Sbjct: 137 AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYE--IPSVRESDAEQYYCVAENGYGPSPS 194
Query: 398 NTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTK 456
V I V +S+P + A + + +E+ CE++ G+ PI Y L + +
Sbjct: 195 GLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSA 254
Query: 457 NSNDPAVFKDNPTED--VEYQCVADN 480
S A F + TE+ Y C A+N
Sbjct: 255 PSGGGASFNLSLTEEHSGNYSCEANN 280
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,078,248
Number of Sequences: 37866
Number of extensions: 1107225
Number of successful extensions: 4748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 3700
Number of HSP's gapped (non-prelim): 1080
length of query: 738
length of database: 18,247,518
effective HSP length: 110
effective length of query: 628
effective length of database: 14,082,258
effective search space: 8843658024
effective search space used: 8843658024
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.