Search of human proteins with 109715835

Search of human proteins with 109715835

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109715835 HEAT repeat containing 6 [Homo sapiens]
         (1181 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109715835 HEAT repeat containing 6 [Homo sapiens]                 2330   0.0  
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H...    38   0.050
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H...    38   0.050
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        38   0.050
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         37   0.11 
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    36   0.19 
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]         35   0.32 
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]         35   0.32 
gi|14149696 SEC31 homolog B [Homo sapiens]                             35   0.42 
gi|55741677 SET domain containing 1A [Homo sapiens]                    35   0.55 
gi|45331213 RAN binding protein 6 [Homo sapiens]                       35   0.55 
gi|55749742 HEAT repeat containing 5B [Homo sapiens]                   34   0.72 
gi|150456424 RW1 protein [Homo sapiens]                                34   0.72 
gi|19913414 adaptor-related protein complex 2, alpha 1 subunit i...    33   1.2  
gi|19913416 adaptor-related protein complex 2, alpha 1 subunit i...    33   1.2  
gi|126722969 centromere protein T [Homo sapiens]                       33   1.6  
gi|4504095 motilin receptor [Homo sapiens]                             33   1.6  
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...    33   1.6  
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    33   2.1  
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ...    33   2.1  
gi|39812229 karyopherin alpha 5 [Homo sapiens]                         33   2.1  
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa...    33   2.1  
gi|32528306 replication factor C large subunit [Homo sapiens]          32   2.7  
gi|6912478 karyopherin alpha 6 [Homo sapiens]                          32   2.7  
gi|9966805 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 [Homo sapiens]    32   2.7  
gi|222144293 karyopherin alpha 1 [Homo sapiens]                        32   3.6  
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    32   3.6  
gi|189181750 human immunodeficiency virus type I enhancer bindin...    32   3.6  
gi|116089331 human immunodeficiency virus type I enhancer bindin...    32   3.6  
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    32   4.7  

>gi|109715835 HEAT repeat containing 6 [Homo sapiens]
          Length = 1181

 Score = 2330 bits (6037), Expect = 0.0
 Identities = 1181/1181 (100%), Positives = 1181/1181 (100%)

Query: 1    MAAVQVVGSWPSVQPREAPREAIPERGNGFRLLSARLCALRPDDSSSARTEIHLLFDQLI 60
            MAAVQVVGSWPSVQPREAPREAIPERGNGFRLLSARLCALRPDDSSSARTEIHLLFDQLI
Sbjct: 1    MAAVQVVGSWPSVQPREAPREAIPERGNGFRLLSARLCALRPDDSSSARTEIHLLFDQLI 60

Query: 61   SENYSEGSGVAPEDVSALLVQACRLVPLNQNHLVSKVSQLIHHLLNRLQVIVDEQHLDFL 120
            SENYSEGSGVAPEDVSALLVQACRLVPLNQNHLVSKVSQLIHHLLNRLQVIVDEQHLDFL
Sbjct: 61   SENYSEGSGVAPEDVSALLVQACRLVPLNQNHLVSKVSQLIHHLLNRLQVIVDEQHLDFL 120

Query: 121  LAYTISAIHQCSSWTHREILQALAALVYCNGSKCQKYLPELLGNTGLLMKLSDLAQSDPE 180
            LAYTISAIHQCSSWTHREILQALAALVYCNGSKCQKYLPELLGNTGLLMKLSDLAQSDPE
Sbjct: 121  LAYTISAIHQCSSWTHREILQALAALVYCNGSKCQKYLPELLGNTGLLMKLSDLAQSDPE 180

Query: 181  VRRAAVHCMANLCLSVPGQPYLEEPYQNVCFQAFLTILQSPKSSDMDDITFCMLLQNALK 240
            VRRAAVHCMANLCLSVPGQPYLEEPYQNVCFQAFLTILQSPKSSDMDDITFCMLLQNALK
Sbjct: 181  VRRAAVHCMANLCLSVPGQPYLEEPYQNVCFQAFLTILQSPKSSDMDDITFCMLLQNALK 240

Query: 241  GIQSLLNGGRMKLTQTDELGALLAVLKKFMFHGLPGLNIEMPTVLYPTPLPQYDGRTPIK 300
            GIQSLLNGGRMKLTQTDELGALLAVLKKFMFHGLPGLNIEMPTVLYPTPLPQYDGRTPIK
Sbjct: 241  GIQSLLNGGRMKLTQTDELGALLAVLKKFMFHGLPGLNIEMPTVLYPTPLPQYDGRTPIK 300

Query: 301  PQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWC 360
            PQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWC
Sbjct: 301  PQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWC 360

Query: 361  PSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAKVR 420
            PSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAKVR
Sbjct: 361  PSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAKVR 420

Query: 421  QGALVCFLSTIKSIEKKVLYGYWSAFIPDTPELGSPQSVSLMTLTLKDPSPKTRACALQV 480
            QGALVCFLSTIKSIEKKVLYGYWSAFIPDTPELGSPQSVSLMTLTLKDPSPKTRACALQV
Sbjct: 421  QGALVCFLSTIKSIEKKVLYGYWSAFIPDTPELGSPQSVSLMTLTLKDPSPKTRACALQV 480

Query: 481  LSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQII 540
            LSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQII
Sbjct: 481  LSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQII 540

Query: 541  KCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQ 600
            KCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQ
Sbjct: 541  KCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQ 600

Query: 601  LLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISI 660
            LLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISI
Sbjct: 601  LLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISI 660

Query: 661  VVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKC 720
            VVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKC
Sbjct: 661  VVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKC 720

Query: 721  MGEADPSIQLHGAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRAL 780
            MGEADPSIQLHGAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRAL
Sbjct: 721  MGEADPSIQLHGAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRAL 780

Query: 781  QNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGV 840
            QNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGV
Sbjct: 781  QNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGV 840

Query: 841  YVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQE 900
            YVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQE
Sbjct: 841  YVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQE 900

Query: 901  EFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQAL 960
            EFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQAL
Sbjct: 901  EFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQAL 960

Query: 961  ISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRS 1020
            ISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRS
Sbjct: 961  ISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRS 1020

Query: 1021 AAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLL 1080
            AAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLL
Sbjct: 1021 AAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLL 1080

Query: 1081 SLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMG 1140
            SLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMG
Sbjct: 1081 SLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMG 1140

Query: 1141 SIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ 1181
            SIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ
Sbjct: 1141 SIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ 1181


>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
           sapiens]
          Length = 929

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 10/176 (5%)

Query: 32  LLSARLCALRPDD---SSSARTEIHLLFDQLISENYSEGSGVAPEDVSALLVQACRLVPL 88
           ++SA +C ++ +    +SS R  +  +F  L+ E    G+ VA     AL+  A     +
Sbjct: 629 VVSAMVCMVKTESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDV 688

Query: 89  NQNHLVSKVSQLIHHLLNRLQVIVDEQHLDFLLAYTISAIH-QCSSWTHREILQALAALV 147
            Q      +++L   + +  ++    + +  ++   +S +H  CS   + E L AL  L 
Sbjct: 689 GQTKAAQALAKLT--ITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLA 746

Query: 148 YCNGSKCQKYLPELLGNTGLLMKLSDLAQSDPEVRRAAVHCMANLCLSVPGQPYLE 203
             +    QK L E      + M    + +    +RRAA  CM NL +S   Q   E
Sbjct: 747 GISERLRQKILKE----KAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFE 798


>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
           sapiens]
          Length = 944

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 10/176 (5%)

Query: 32  LLSARLCALRPDD---SSSARTEIHLLFDQLISENYSEGSGVAPEDVSALLVQACRLVPL 88
           ++SA +C ++ +    +SS R  +  +F  L+ E    G+ VA     AL+  A     +
Sbjct: 644 VVSAMVCMVKTESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDV 703

Query: 89  NQNHLVSKVSQLIHHLLNRLQVIVDEQHLDFLLAYTISAIH-QCSSWTHREILQALAALV 147
            Q      +++L   + +  ++    + +  ++   +S +H  CS   + E L AL  L 
Sbjct: 704 GQTKAAQALAKLT--ITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLA 761

Query: 148 YCNGSKCQKYLPELLGNTGLLMKLSDLAQSDPEVRRAAVHCMANLCLSVPGQPYLE 203
             +    QK L E      + M    + +    +RRAA  CM NL +S   Q   E
Sbjct: 762 GISERLRQKILKE----KAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFE 813


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 49/200 (24%), Positives = 69/200 (34%), Gaps = 12/200 (6%)

Query: 219  QSPKSSDMDDITFCMLLQNA-LKGIQSLLNGGRMKLTQT--DELGALLAVLKKFMFHGLP 275
            +SP  S   D + C++ Q   + G QSL +G     T +  D  G L          G+P
Sbjct: 2448 RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP-----GVP 2502

Query: 276  GLNIEMPTVLYPTPLPQ-YDGRTPIKPQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEK 334
              ++  P        P       P K ++S SS+S  + +    S         G     
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562

Query: 335  ESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRV 394
                 +   P     RV      T  P     +  P + + A  K   SSS SSSS    
Sbjct: 2563 SEGSSLPVQPEVALKRV---PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSS 2619

Query: 395  SSSESDFSDAEGGMQSKMRS 414
            SSS S  S +     S   S
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSS 2639


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 32/113 (28%), Positives = 43/113 (38%), Gaps = 4/113 (3%)

Query: 302  QQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWCP 361
            ++SESS+S  + +    S         G E E E  G+       GTG  N    ++   
Sbjct: 2555 EESESSSSSSSGSSSSSSSSS----SSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610

Query: 362  SSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRS 414
            S     S     S ++     SSS SSSS    SSS S  S +     S   S
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 36.2 bits (82), Expect = 0.19
 Identities = 32/134 (23%), Positives = 54/134 (40%), Gaps = 11/134 (8%)

Query: 287 PTPLPQYDGRTPIKPQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEI-EAAPV 345
           P P P+   + P     + + + +P+  K+KKS  K  +   G      SS    +  P 
Sbjct: 276 PPPPPRASSKRP-----ATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPA 330

Query: 346 -----TGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESD 400
                T   +V           +L V+    +   + + +   SS S+SS    SSS+SD
Sbjct: 331 KDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSD 390

Query: 401 FSDAEGGMQSKMRS 414
           F  ++   Q  +RS
Sbjct: 391 FEPSQNHSQGPLRS 404


>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
          Length = 1251

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 15/154 (9%)

Query: 274 LPGLN-IEMPTVLYPT--PLPQYDGRTPIK----PQQSESSASRPTLNKKKKSKVKPKKI 326
           LP L+ I+ P  + PT  P P  D +        P++ ++    P       S ++    
Sbjct: 337 LPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLK 396

Query: 327 QQGEEEEKESSGEIEAA--PVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSS 384
              +EEE E       A   ++ +  V      T  PSS G  S    GS ++  D  SS
Sbjct: 397 LSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESS 456

Query: 385 SFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAK 418
           S S       S +ES  S++EG       S +A+
Sbjct: 457 SGSD------SETESSSSESEGSKPPHFSSPEAE 484


>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
          Length = 1226

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 15/154 (9%)

Query: 274 LPGLN-IEMPTVLYPT--PLPQYDGRTPIK----PQQSESSASRPTLNKKKKSKVKPKKI 326
           LP L+ I+ P  + PT  P P  D +        P++ ++    P       S ++    
Sbjct: 312 LPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLK 371

Query: 327 QQGEEEEKESSGEIEAA--PVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSS 384
              +EEE E       A   ++ +  V      T  PSS G  S    GS ++  D  SS
Sbjct: 372 LSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESS 431

Query: 385 SFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAK 418
           S S       S +ES  S++EG       S +A+
Sbjct: 432 SGSD------SETESSSSESEGSKPPHFSSPEAE 459


>gi|14149696 SEC31 homolog B [Homo sapiens]
          Length = 1179

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 15/27 (55%), Positives = 17/27 (62%)

Query: 606 PCSSGLGNSNSATPHLSPPDWWKKAPA 632
           PCSS L  +   TPH  P D WK+APA
Sbjct: 973 PCSSVLPTTGILTPHPGPQDSWKEAPA 999


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 34.7 bits (78), Expect = 0.55
 Identities = 36/142 (25%), Positives = 54/142 (38%), Gaps = 14/142 (9%)

Query: 295  GRTPIKPQQSESSASRPTLNKKKKS------------KVKPKKIQQGEEEEKESSGEIEA 342
            GR   KP + +    + T  K +KS            +   +K ++ +EE++E     EA
Sbjct: 935  GRPGTKPPKRDEERGK-TQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEA 993

Query: 343  APVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESDFS 402
               T      + +G      S    SL  D  G  +    S S SSSS    SSS S  S
Sbjct: 994  VDTTKK-ETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSS 1052

Query: 403  DAEGGMQSKMRSYQAKVRQGAL 424
             +    +S     + + R  AL
Sbjct: 1053 SSSSSSESSSEDEEEEERPAAL 1074


>gi|45331213 RAN binding protein 6 [Homo sapiens]
          Length = 1105

 Score = 34.7 bits (78), Expect = 0.55
 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 9/87 (10%)

Query: 846 CLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGL 905
           C +Q    + +  N++L+ L+D    VRA A  +LG +            P+FQ++F   
Sbjct: 397 CHQQMESILDETVNSVLLFLQDPHPRVRAAACTTLGQMATDFA-------PNFQKKFHET 449

Query: 906 LLLKMLRSAIEASKDKDKVKSNAVRAL 932
           ++  +LR+    ++   +V+S+A  AL
Sbjct: 450 VIAALLRTM--ENQGNQRVQSHAASAL 474


>gi|55749742 HEAT repeat containing 5B [Homo sapiens]
          Length = 2071

 Score = 34.3 bits (77), Expect = 0.72
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 16/107 (14%)

Query: 128  IHQCSSWTHREILQALAALVYCNGSKCQKYLPELLGNTGLLMKLSDL-----------AQ 176
            +H  +SW    IL A+A  +   G  C +   E    +GL  + + +           A+
Sbjct: 1522 LHYRNSWA--PILHAVALWLNSTGFTCSEST-EAAAISGLQKRSTSVNLNQASGAVGSAK 1578

Query: 177  SDPEVRRAAVHCMANLCLSVPGQPYLEEPYQNV--CFQAFLTILQSP 221
            S PE+ +  +H +  + +     P  EEP ++V  C QA  T+L SP
Sbjct: 1579 SLPEINKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLDSP 1625


>gi|150456424 RW1 protein [Homo sapiens]
          Length = 1883

 Score = 34.3 bits (77), Expect = 0.72
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 13/102 (12%)

Query: 247  NGGRMKLTQTDELGALLAVLKKFMFHGLPGLNI--EMPTVLYPTPLPQYDGRTPIKPQQS 304
            +  R     +D    + A+ K F  H  P L +  E P    P+PLP+  G+   KP Q 
Sbjct: 1336 SSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQP----PSPLPKSKGKG--KPLQR 1389

Query: 305  ESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVT 346
            +    +    K+KK K KP+     E+E K+S  + +++  T
Sbjct: 1390 KVKPPKKQEEKEKKGKGKPQ-----EDELKDSLADDDSSSTT 1426


>gi|19913414 adaptor-related protein complex 2, alpha 1 subunit
           isoform 1 [Homo sapiens]
          Length = 977

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 40/204 (19%), Positives = 81/204 (39%), Gaps = 38/204 (18%)

Query: 419 VRQGALVCFLSTIKSIEKKVLYGYWSAFIP---DTPELGS-PQSVSLMTLTLKDPSPKTR 474
           V+Q A +C L   K+    V  G W+A +    +   +G    +VSL+T   K      +
Sbjct: 164 VKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFK 223

Query: 475 ACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQ 534
            C    +S +   S+   S + D  D+   F P   +    +R     LL        + 
Sbjct: 224 TCVSLAVSRL---SRIVSSASTDLQDYTYYFVPAPWLSVKLLR-----LLQCYPPPEDAA 275

Query: 535 TVTQIIKCLANLVSNAP------------------YDRLKL--------SLLTKVWNQIK 568
              ++++CL  +++ A                   ++ + L        +LL +  NQ+ 
Sbjct: 276 VKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLG 335

Query: 569 PYIRHKDVNVRVSSLTLLGAIVST 592
            +++H++ N+R  +L  +  + S+
Sbjct: 336 QFLQHRETNLRYLALESMCTLASS 359


>gi|19913416 adaptor-related protein complex 2, alpha 1 subunit
           isoform 2 [Homo sapiens]
          Length = 955

 Score = 33.5 bits (75), Expect = 1.2
 Identities = 40/204 (19%), Positives = 81/204 (39%), Gaps = 38/204 (18%)

Query: 419 VRQGALVCFLSTIKSIEKKVLYGYWSAFIP---DTPELGS-PQSVSLMTLTLKDPSPKTR 474
           V+Q A +C L   K+    V  G W+A +    +   +G    +VSL+T   K      +
Sbjct: 164 VKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFK 223

Query: 475 ACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQ 534
            C    +S +   S+   S + D  D+   F P   +    +R     LL        + 
Sbjct: 224 TCVSLAVSRL---SRIVSSASTDLQDYTYYFVPAPWLSVKLLR-----LLQCYPPPEDAA 275

Query: 535 TVTQIIKCLANLVSNAP------------------YDRLKL--------SLLTKVWNQIK 568
              ++++CL  +++ A                   ++ + L        +LL +  NQ+ 
Sbjct: 276 VKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLG 335

Query: 569 PYIRHKDVNVRVSSLTLLGAIVST 592
            +++H++ N+R  +L  +  + S+
Sbjct: 336 QFLQHRETNLRYLALESMCTLASS 359


>gi|126722969 centromere protein T [Homo sapiens]
          Length = 561

 Score = 33.1 bits (74), Expect = 1.6
 Identities = 25/70 (35%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 331 EEEKESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQ-SLPLDGSGAAEKDGVSSSFSSS 389
           EEE  S  E+EA    G  RV   EG+T    + G Q +   DG GA+  D  +S  ++S
Sbjct: 338 EEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAAS 397

Query: 390 SWKRVSSSES 399
                S+ ES
Sbjct: 398 PESASSTPES 407


>gi|4504095 motilin receptor [Homo sapiens]
          Length = 412

 Score = 33.1 bits (74), Expect = 1.6
 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 12/75 (16%)

Query: 634 PSLEETS--VSSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAG---STYEPSPMR 688
           P L  T+   SSP  SS P WL R        P     SG +   AA        PSP +
Sbjct: 189 PGLNGTARIASSPLASSPPLWLSRA-------PPPSPPSGPETAEAAALFSRECRPSPAQ 241

Query: 689 LEALQVLTLLARGYF 703
           L AL+V+  +   YF
Sbjct: 242 LGALRVMLWVTTAYF 256


>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo
           sapiens]
          Length = 1555

 Score = 33.1 bits (74), Expect = 1.6
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 19/97 (19%)

Query: 554 RLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGN 613
           R  L  L   W++I P  +   ++VRV+SL     I     PLP               N
Sbjct: 112 RKSLFKLRSTWDEIFPLKKLYALDVRVNSLDPAWPI----KPLPP--------------N 153

Query: 614 SNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEP 650
            N+++ H++P  +  K+P  PS   T VSSP  S+ P
Sbjct: 154 VNTSSIHVNPK-FLNKSPEEPSTPGTVVSSPSISTPP 189


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 9/121 (7%)

Query: 372 DGSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAKVRQG--ALVCFLS 429
           + +      G    FSS   K     +   S+ +      M+     + +G  A   F +
Sbjct: 23  EATSTISPSGAFGLFSSDLKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPA 82

Query: 430 TIKSIE------KKVLYGYWSAFIPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSA 483
            +K++       KK++Y Y   +  +  +L    S+S     LKDP+   RA AL+VLS+
Sbjct: 83  VVKNVASKNIEIKKLVYVYLVRYAEEQQDLAL-LSISTFQRALKDPNQLIRASALRVLSS 141

Query: 484 I 484
           I
Sbjct: 142 I 142


>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
           sapiens]
          Length = 817

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 8/68 (11%)

Query: 287 PTPLPQYDG-----RTPI--KPQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESS-G 338
           P P P  D      R P   +P Q   + +RP    ++  K+KP ++++  E E ES+ G
Sbjct: 257 PPPAPSGDAPAEKERCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPG 316

Query: 339 EIEAAPVT 346
           E+  A VT
Sbjct: 317 EVIQAEVT 324


>gi|39812229 karyopherin alpha 5 [Homo sapiens]
          Length = 539

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 783 SEHPTLQASACDALSSILPEAFSNLPNDRQMLCI--------TVLLGLNDSKNRLVKAAT 834
           S  P + A  C ALS +     S+ PND+    I          LL  ND K   V +  
Sbjct: 266 SSDPDVLADVCWALSYL-----SDGPNDKIQAVIDSGVCRRLVELLMHNDYK---VVSPA 317

Query: 835 SRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLT 884
            RA+G  V    ++  VI    A   +L  L     ++R +A W++ N+T
Sbjct: 318 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNIT 367


>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
            sapiens]
          Length = 2881

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 3/109 (2%)

Query: 322  KPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDG 381
            KP+  ++G E   +S  + E +  +   R +    ++ C  S    S     S ++    
Sbjct: 2120 KPRVHKRGSESSSDSDSDSERSSCSS--RSSSSSSSSSCSHSRSGSSSSSSSSCSSASSS 2177

Query: 382  VSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAKVRQGALVCFLST 430
             SSS SSSS    SSSE   SD E   Q +  +   K      V  LST
Sbjct: 2178 SSSSTSSSSSSSSSSSEESDSDEEEA-QKRESTTHMKAYDEESVASLST 2225


>gi|32528306 replication factor C large subunit [Homo sapiens]
          Length = 1147

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 9/81 (11%)

Query: 288 TPLPQYDGRTPIKP--QQSESSASRPTLNK-------KKKSKVKPKKIQQGEEEEKESSG 338
           TP     G+  I P  ++SES  SRPT  +       KK++ V  K +   E+  +E+SG
Sbjct: 506 TPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAKTIKKETDVFWKSLDFKEQVAEETSG 565

Query: 339 EIEAAPVTGTGRVNLHEGNTW 359
           + +A  +      N  E   W
Sbjct: 566 DSKARNLADDSSENKVENLLW 586


>gi|6912478 karyopherin alpha 6 [Homo sapiens]
          Length = 536

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 775 PLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCI--------TVLLGLNDSK 826
           P+   L  S    L A AC ALS +     S+ PN++    I          LL  ND K
Sbjct: 255 PVLSRLLFSSDSDLLADACWALSYL-----SDGPNEKIQAVIDSGVCRRLVELLMHNDYK 309

Query: 827 NRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLT 884
              V +   RA+G  V    ++  VI    A   +L  L     ++R +A W++ N+T
Sbjct: 310 ---VASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT 364


>gi|9966805 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 [Homo sapiens]
          Length = 859

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 10/99 (10%)

Query: 243 QSLLNGGRMKLTQTDELGALLAVLKKFMFHGLPG-LNIEMPTVLYPTPLPQYDGRTPI-- 299
           + +  GG+    +       + VLKK + H L   L  E     YPT      G+ P+  
Sbjct: 765 EDMYKGGKADQQEERRRQKQMKVLKKELRHLLSQPLFTESQKTKYPTQ----SGKPPLLV 820

Query: 300 -KPQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESS 337
             P +SES+ S   L+K+KK K K  K  Q E+ +  +S
Sbjct: 821 SAPSKSESALS--CLSKQKKKKTKKPKEPQPEQPQPSTS 857


>gi|222144293 karyopherin alpha 1 [Homo sapiens]
          Length = 538

 Score = 32.0 bits (71), Expect = 3.6
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 16/103 (15%)

Query: 790 ASACDALSSILPEAFSNLPNDRQMLCITV--------LLGLNDSKNRLVKAATSRALGVY 841
           A AC ALS +     S+ PND+    I          LL  ND K   V +   RA+G  
Sbjct: 272 ADACWALSYL-----SDGPNDKIQAVIDAGVCRRLVELLMHNDYK---VVSPALRAVGNI 323

Query: 842 VLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLT 884
           V    ++  VI    A  ++L  L     +++ +A W++ N+T
Sbjct: 324 VTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT 366


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 32.0 bits (71), Expect = 3.6
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%)

Query: 380 DGVSSSFSSSSWKRVSSSESDFSDAEGGMQSK-MRSYQAKVRQG--ALVCFLSTIKSIE- 435
           D  S    SS +KR    +      +  ++ + M+   A + +G  A   F + +K++  
Sbjct: 25  DPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVAC 84

Query: 436 -----KKVLYGYWSAFIPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAI 484
                KK++Y Y   +  +  +L    S+S     LKDP+   RA AL+VLS+I
Sbjct: 85  KNIEVKKLVYVYLVRYAEEQQDLAL-LSISTFQRGLKDPNQLIRASALRVLSSI 137


>gi|189181750 human immunodeficiency virus type I enhancer binding
           protein 3 b [Homo sapiens]
          Length = 2405

 Score = 32.0 bits (71), Expect = 3.6
 Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 6/113 (5%)

Query: 278 NIEMPTVLY------PTPLPQYDGRTPIKPQQSESSASRPTLNKKKKSKVKPKKIQQGEE 331
           NI++P +L       P   P+   + P K ++ +      TL +    K+ PKK +    
Sbjct: 852 NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLA 911

Query: 332 EEKESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSS 384
           E  +SSGE          R    E N     S    S   D  G AE    SS
Sbjct: 912 EMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSS 964


>gi|116089331 human immunodeficiency virus type I enhancer binding
           protein 3 [Homo sapiens]
          Length = 2406

 Score = 32.0 bits (71), Expect = 3.6
 Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 6/113 (5%)

Query: 278 NIEMPTVLY------PTPLPQYDGRTPIKPQQSESSASRPTLNKKKKSKVKPKKIQQGEE 331
           NI++P +L       P   P+   + P K ++ +      TL +    K+ PKK +    
Sbjct: 852 NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLA 911

Query: 332 EEKESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSS 384
           E  +SSGE          R    E N     S    S   D  G AE    SS
Sbjct: 912 EMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSS 964


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 31.6 bits (70), Expect = 4.7
 Identities = 39/153 (25%), Positives = 59/153 (38%), Gaps = 8/153 (5%)

Query: 254 TQTDELGALLAVLKKFMFHGLPGLN-IEMPTVLYPTPLPQYDGRTPIKPQQSESSASRPT 312
           T ++E+  +  +LK+      P L  I  P+   P+  P      P K  Q  SS ++  
Sbjct: 348 TYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFP-----FPTKDSQHVSSVTQNQ 402

Query: 313 LNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQSLPLD 372
                 SK      QQG     E   ++  +  + + +      ++  P S   QSLP  
Sbjct: 403 KQYDTSSKTHSNS-QQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS-APQSLPEP 460

Query: 373 GSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAE 405
            + A      S S S S     S SES  SD+E
Sbjct: 461 VASAHSSSAESESTSDSDSSSDSESESSSSDSE 493


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,528,123
Number of Sequences: 37866
Number of extensions: 2036651
Number of successful extensions: 8090
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 7883
Number of HSP's gapped (non-prelim): 155
length of query: 1181
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1068
effective length of database: 13,968,660
effective search space: 14918528880
effective search space used: 14918528880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.