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Search of human proteins with 149944613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens]
(1404 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens] 2834 0.0
gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens] 2834 0.0
gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens] 2003 0.0
gi|149944548 neurobeachin-like 2 [Homo sapiens] 1385 0.0
gi|62422577 neurobeachin [Homo sapiens] 498 e-140
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho... 491 e-138
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 395 e-109
gi|31543297 neutral sphingomyelinase (N-SMase) activation associ... 336 8e-92
gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc... 336 8e-92
gi|191252801 WDFY family member 4 [Homo sapiens] 325 2e-88
gi|54292123 lysosomal trafficking regulator [Homo sapiens] 324 3e-88
gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] 102 3e-21
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] 102 3e-21
gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens] 102 3e-21
gi|32189425 WD repeat domain 69 [Homo sapiens] 57 2e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 2e-05
gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens] 50 2e-05
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 49 3e-05
gi|89886480 zinedin isoform 2 [Homo sapiens] 49 3e-05
gi|89886477 zinedin isoform 1 [Homo sapiens] 49 3e-05
gi|157266266 WD repeat domain 86 [Homo sapiens] 49 3e-05
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 49 4e-05
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 49 4e-05
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 49 4e-05
gi|142976686 nuclear autoantigen isoform 1 [Homo sapiens] 48 8e-05
gi|142976675 nuclear autoantigen isoform 2 [Homo sapiens] 48 8e-05
gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [... 47 1e-04
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 47 2e-04
gi|16554629 WD repeat domain 5 [Homo sapiens] 46 2e-04
gi|16554627 WD repeat domain 5 [Homo sapiens] 46 2e-04
>gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens]
Length = 2694
Score = 2834 bits (7346), Expect = 0.0
Identities = 1404/1404 (100%), Positives = 1404/1404 (100%)
Query: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV
Sbjct: 1291 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 1350
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH
Sbjct: 1351 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 1410
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV
Sbjct: 1411 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 1470
Query: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL
Sbjct: 1471 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 1530
Query: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA
Sbjct: 1531 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 1590
Query: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL
Sbjct: 1591 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 1650
Query: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA
Sbjct: 1651 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 1710
Query: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA
Sbjct: 1711 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 1770
Query: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR
Sbjct: 1771 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 1830
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL
Sbjct: 1831 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 1890
Query: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR
Sbjct: 1891 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 1950
Query: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR
Sbjct: 1951 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 2010
Query: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE
Sbjct: 2011 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 2070
Query: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA
Sbjct: 2071 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 2130
Query: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK
Sbjct: 2131 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 2190
Query: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL
Sbjct: 2191 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 2250
Query: 961 DALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPE 1020
DALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPE
Sbjct: 2251 DALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPE 2310
Query: 1021 LKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISN 1080
LKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISN
Sbjct: 2311 LKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISN 2370
Query: 1081 YFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTK 1140
YFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTK
Sbjct: 2371 YFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTK 2430
Query: 1141 GKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYG 1200
GKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYG
Sbjct: 2431 GKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYG 2490
Query: 1201 HTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWE 1260
HTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWE
Sbjct: 2491 HTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWE 2550
Query: 1261 GHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLS 1320
GHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLS
Sbjct: 2551 GHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLS 2610
Query: 1321 IRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRK 1380
IRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRK
Sbjct: 2611 IRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRK 2670
Query: 1381 FWGSSKRLSQISAGETEYNTQDSK 1404
FWGSSKRLSQISAGETEYNTQDSK
Sbjct: 2671 FWGSSKRLSQISAGETEYNTQDSK 2694
>gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens]
Length = 1404
Score = 2834 bits (7346), Expect = 0.0
Identities = 1404/1404 (100%), Positives = 1404/1404 (100%)
Query: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV
Sbjct: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH
Sbjct: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV
Sbjct: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
Query: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL
Sbjct: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
Query: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA
Sbjct: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
Query: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL
Sbjct: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
Query: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA
Sbjct: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
Query: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA
Sbjct: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
Query: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR
Sbjct: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL
Sbjct: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
Query: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR
Sbjct: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
Query: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR
Sbjct: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
Query: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE
Sbjct: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
Query: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA
Sbjct: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
Query: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK
Sbjct: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
Query: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL
Sbjct: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
Query: 961 DALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPE 1020
DALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPE
Sbjct: 961 DALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPE 1020
Query: 1021 LKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISN 1080
LKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISN
Sbjct: 1021 LKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISN 1080
Query: 1081 YFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTK 1140
YFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTK
Sbjct: 1081 YFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTK 1140
Query: 1141 GKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYG 1200
GKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYG
Sbjct: 1141 GKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYG 1200
Query: 1201 HTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWE 1260
HTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWE
Sbjct: 1201 HTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWE 1260
Query: 1261 GHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLS 1320
GHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLS
Sbjct: 1261 GHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLS 1320
Query: 1321 IRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRK 1380
IRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRK
Sbjct: 1321 IRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRK 1380
Query: 1381 FWGSSKRLSQISAGETEYNTQDSK 1404
FWGSSKRLSQISAGETEYNTQDSK
Sbjct: 1381 FWGSSKRLSQISAGETEYNTQDSK 1404
>gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens]
Length = 1335
Score = 2003 bits (5189), Expect = 0.0
Identities = 988/988 (100%), Positives = 988/988 (100%)
Query: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV
Sbjct: 1 MKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSV 60
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH
Sbjct: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV
Sbjct: 121 SDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQV 180
Query: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL
Sbjct: 181 FSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFL 240
Query: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA
Sbjct: 241 QSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCA 300
Query: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL
Sbjct: 301 MASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYEL 360
Query: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA
Sbjct: 361 LFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMA 420
Query: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA
Sbjct: 421 LYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLA 480
Query: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR
Sbjct: 481 TLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALR 540
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL
Sbjct: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVL 600
Query: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR
Sbjct: 601 MEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRR 660
Query: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR
Sbjct: 661 SALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNR 720
Query: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE
Sbjct: 721 EISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNE 780
Query: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA
Sbjct: 781 KNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCA 840
Query: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK
Sbjct: 841 DRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPK 900
Query: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL
Sbjct: 901 WAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDL 960
Query: 961 DALTDEKERKALEGMINNFGQTPCQLLK 988
DALTDEKERKALEGMINNFGQTPCQLLK
Sbjct: 961 DALTDEKERKALEGMINNFGQTPCQLLK 988
Score = 699 bits (1804), Expect = 0.0
Identities = 348/349 (99%), Positives = 348/349 (99%)
Query: 1056 LLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV 1115
L ITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV
Sbjct: 987 LKITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFV 1046
Query: 1116 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1175
VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC
Sbjct: 1047 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1106
Query: 1176 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1235
MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ
Sbjct: 1107 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1166
Query: 1236 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1295
YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI
Sbjct: 1167 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1226
Query: 1296 LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG 1355
LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG
Sbjct: 1227 LKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVG 1286
Query: 1356 LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 1404
LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK
Sbjct: 1287 LEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 1335
>gi|149944548 neurobeachin-like 2 [Homo sapiens]
Length = 2754
Score = 1385 bits (3585), Expect = 0.0
Identities = 733/1418 (51%), Positives = 973/1418 (68%), Gaps = 94/1418 (6%)
Query: 73 FWHS-----NPSHLSLDLSGIDSCEMS----DSGSQVPDSLPSTPSPVESTKSFSV---- 119
F+H+ P L L+ S + S + SG+ P S P TPSP++ + F
Sbjct: 1345 FYHALSPFCTPFDLGLERSSVGSGNTAGGGGSSGTLTPASQPGTPSPLDGPRPFPAAPGR 1404
Query: 120 HSDRESSITND-------MGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDD 172
HS S++ D + D + Q+ EEEL LLT++L V +G+E SD+
Sbjct: 1405 HSSSLSNVLEDGSLPEPTISGDDTSNTSNPQQTSEEELCNLLTNVLFSVTWRGVEGSDEA 1464
Query: 173 TWIERGQVFSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTA--ENAF 230
W ERGQVFS L++ G S+ L+RP D IK +LL+ MLE A+++ +EA + + + A
Sbjct: 1465 AWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPVGVLASLTQQAL 1524
Query: 231 RLVLIIQDFLQSEGLVNSNMWTEKLLEDMMLLFDCLSV---CYSESPVWVKLSQIQIQLL 287
L+ ++QDFL +EG N +W+EKL E + L D L + + +++QI ++L+
Sbjct: 1525 WLLRLLQDFLCAEGHGNQELWSEKLFEGVCSLLDRLGAWPHLANGTADLREMAQIGLRLV 1584
Query: 288 LGFIGRGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQT------- 340
LG+I + Q+ A A +L+ LLQT V ++EACY+L KLE L + + +
Sbjct: 1585 LGYILLEDPQLHAQAYVRLHMLLQTAVPARREEACYVLSKLEAALGRVLNTSSLESATDE 1644
Query: 341 --------------EIYSFLIPLVRTLVSKIYELLFMNLHLPSLPFTNGSSSFFEDFQEY 386
E S+L+PLVRTL+ + YE L + LPSLP TNGS +FFEDFQ +
Sbjct: 1645 AGSPLAAAAAAAAAERCSWLVPLVRTLLDRAYEPLGLQWGLPSLPPTNGSPTFFEDFQAF 1704
Query: 387 CNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMALYWKDCYEALMVNMHKRDREGGESKL 446
C + EW+ +I+K + P M Q+E T+ H+ M+ +W CY+ LM + +R E +S+
Sbjct: 1705 CATPEWRHFIDKQVQPTMSQFEMDTYAKSHDLMSGFWNACYDMLMSSGQRRQWERAQSRR 1764
Query: 447 KFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRWKAIQLYLTCERGPWAKRKQNP 506
FQEL +EP R+AR E LRY +LKQ ++Q L W A+ L G WA R
Sbjct: 1765 AFQELVLEPAQRRARLEGLRYTAVLKQQATQHSMALLHWGALWRQLASPCGAWALRDTPI 1824
Query: 507 IHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDTLL-LEVVKQVKV 565
WKL++ E YSRMRLKLVPN++F H EASALRDNLG P+ + L L V K+ KV
Sbjct: 1825 PRWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEVPLTPTEEASLPLAVTKEAKV 1884
Query: 566 SD----MVEDKLDLPEEDITARVN--VDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEI 619
S + ED+L ED A + ++ E +Q+EKLVL +C+L+T++ V+PG LE+
Sbjct: 1885 STPPELLQEDQLG---EDELAELETPMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEV 1941
Query: 620 TTQHIYFYDGS---IEKEDGVGFDFKWPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLN 676
TTQ++YFYDGS +E E+G+G+DF+ P +Q+RE+HLRR+NLRRSALE+F +DQ+NYFLN
Sbjct: 1942 TTQNVYFYDGSTERVETEEGIGYDFRRPLAQLREVHLRRFNLRRSALELFFIDQANYFLN 2001
Query: 677 FK-------------------------KEVRNKIYSRLLSLHSPNS-YYGSRSPQELFKA 710
F +VRN++YS LL L P+ Y SRSPQE+ +A
Sbjct: 2002 FPCKVGTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPPSQGYLSSRSPQEMLRA 2061
Query: 711 SGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRD 770
SGLTQKWV REISNF+YL+Q+NT+AGRTYNDL+QYPVFPW+LQDY S LDL+NPAVFRD
Sbjct: 2062 SGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRD 2121
Query: 771 LSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHI 830
LSKPIGVVN K+A+ +REKYE+FEDP GTIDKFHYGTHYSN+AGVMHYLIRVEPFT+LH+
Sbjct: 2122 LSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHV 2181
Query: 831 QLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISK 890
QLQSGRFDC+DRQFHS+ A WQA +++P DVKELIPEFFYFP+FLENQN F+LG LQ++
Sbjct: 2182 QLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTN 2241
Query: 891 ELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFY 950
E V DV+LP WA S EDFI +HR+ALESEYVSAHLHEWIDLIFGYKQRGPAA EALNVFY
Sbjct: 2242 EKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFY 2301
Query: 951 YCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTS 1010
YC+YEGAVDLD +TDE+ERKALEG+I+NFGQTPCQLLKEPHP RLSAEEA + ++DT+
Sbjct: 2302 YCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEEAAHRLARLDTN 2361
Query: 1011 TLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHG 1070
+ ++FQHL ELK+FF E +SDG+PL+ A +P Q SF++QGSP+LL+T+S + ++GTH
Sbjct: 2362 SPSIFQHLDELKAFFAEVVSDGVPLVLALVPHRQPHSFITQGSPDLLVTVSASGLLGTHS 2421
Query: 1071 WLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWD 1130
WLPYDRNISNYF+F KD T+ + KTQR ++G + PG ++ + V+ D KLLFS G+WD
Sbjct: 2422 WLPYDRNISNYFSFSKDPTMGSHKTQRLLSGPWVPGSGVSGQALAVAPDGKLLFSGGHWD 2481
Query: 1131 NSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGL 1190
S++V +L +GK++S + H+D+VTCLA D CGI+LISGSRDTTCM+W++ QGG+ VGL
Sbjct: 2482 GSLRVTALPRGKLLSQLSCHLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGL 2541
Query: 1191 ASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFL 1250
A KP Q+LYGH V V ISTELDMAVSGS DGTVIIHT+++GQ++ LRP L
Sbjct: 2542 APKPVQVLYGHGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRP-----LGA 2596
Query: 1251 TIP----NLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICII 1306
T P +LA+ EG IVV SS E+ + +LHL+S+NGK S L EQ + + +
Sbjct: 2597 TFPGPIFHLALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASLPLAEQPTALTVT 2656
Query: 1307 GEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGV 1366
+ ++ G+ Q L I L++L + PL M++ I V VTKE SH+LVGLEDGKLIVV
Sbjct: 2657 EDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERSHVLVGLEDGKLIVVVA 2716
Query: 1367 GKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK 1404
G+P+E+RS Q +RK W SS+R+SQ+S+GETEYN +++
Sbjct: 2717 GQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPTEAR 2754
>gi|62422577 neurobeachin [Homo sapiens]
Length = 2946
Score = 498 bits (1283), Expect = e-140
Identities = 357/1054 (33%), Positives = 530/1054 (50%), Gaps = 89/1054 (8%)
Query: 316 ENQDEACYILGKLEHVLSQSIKEQTEIYSFLIP-LVRTLV-SKIYELLFMNLHLPSLPFT 373
E+ E I KLE L + EI+ P L RTL+ S ELL + L
Sbjct: 1876 EDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELL-----IEGLVCM 1930
Query: 374 NGSSSFFEDFQEYCNSNEWQVYIEKYI-VPYMKQYE-----AHTFYDGHENMALYWKDCY 427
S+S E C S EWQ I+K + +++ H D +A
Sbjct: 1931 KSSTSVVELVMLLC-SQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVA------N 1983
Query: 428 EALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRWKA 487
EA + ++++ E +F+ + + R+E ++++ + T + K
Sbjct: 1984 EAEFI-LNRQRAEDVHKHAEFESQCAQ-YAADRREEEKMCDHLISAAKHRDHVTANQLKQ 2041
Query: 488 -IQLYLTCERGPWAKRKQNPIH--WKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLG 544
I LT + G W + +H W+L E+ R R + V N TH EA
Sbjct: 2042 KILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALL---KAA 2098
Query: 545 IQHSQPSSDTLLLEVVK-QVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVLMED 603
I++ + + Q V+ E +L L +D + + EKE + +VL
Sbjct: 2099 IEYGTEEDVVKSKKTFRSQAIVNQNAETELMLEGDDDAVSL-LQEKEIDNLAGPVVLSTP 2157
Query: 604 CELITIIDVIPGRLEITTQHIYFY----DGSIEKEDGV------GFDFKWPHSQIREIHL 653
+LI + V G L ITT IYF D + +K D G KW S+IR +
Sbjct: 2158 AQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFS 2217
Query: 654 RRYNLRRSALEIFHVDQSNYFLNFKKE--VRNKIYSRLLSLHSPNSYYGS--------RS 703
RRY L+ +ALE+F ++++ NF + V+ +YS L + YG +
Sbjct: 2218 RRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYS--LPRVGVGTSYGLPQARRISLAT 2275
Query: 704 PQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLN 763
P++L+K+S +TQ+W REISNF+YL+ +NT+AGRTYNDL QYPVFPW+L +Y SEELDL
Sbjct: 2276 PRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLT 2335
Query: 764 NPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVE 823
P FRDLSKPIG +N K A E+YE +ED +HY THYS + + +L+R+E
Sbjct: 2336 LPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSP--PYHYNTHYSTATSTLSWLVRIE 2393
Query: 824 PFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNL 883
PFTT + G+FD DR F S+ +W+ + DVKELIPEF+Y PE N N +NL
Sbjct: 2394 PFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNL 2453
Query: 884 GRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAV 943
G ++ + +VNDV LP WAK EDF+ +R ALESE+VS LH+WIDLIFGYKQRGP AV
Sbjct: 2454 G-VREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAV 2512
Query: 944 EALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQK 1003
ALNVF+Y +YEG+V+LD++TD R+A+E I NFGQTP QLL EPHPPR SA
Sbjct: 2513 RALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFL 2572
Query: 1004 PTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKA---TIPKNQYRSFMSQGSPELLITI 1060
P + +F+ + + P+ T+P + ++ L
Sbjct: 2573 P-----QSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVN 2627
Query: 1061 SMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPK--TQRSINGSFAPGLEITSKLFVVSH 1118
+ +G G Y + +++ D + N +R I ++I + FVV+
Sbjct: 2628 RWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTA 2687
Query: 1119 DAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLA--TDYCG--IHLISGSRDTT 1174
D + + G+WD S +V S GK+ + H D+VTCLA Y G +++SGSRD T
Sbjct: 2688 DNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDAT 2747
Query: 1175 CMIWQITQQ----GGVPVGL-ASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIH 1229
++W + + G P P +L GH +EV+ V + EL + +SG+++G ++H
Sbjct: 2748 LLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVH 2807
Query: 1230 TIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGK 1289
TI G +R L P E+ LF + +++S EGH ++Y ++ FSINGK
Sbjct: 2808 TI-TGDLLRALEGP-ENCLFPRL--ISVSSEGHCIIY---------YERGRFSNFSINGK 2854
Query: 1290 YLGSQILKEQVSDICII--GEHIVTGSIQGFLSI 1321
L + + I + G+++VTG G + +
Sbjct: 2855 LLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEV 2888
>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
containing [Homo sapiens]
Length = 2863
Score = 491 bits (1263), Expect = e-138
Identities = 368/1111 (33%), Positives = 562/1111 (50%), Gaps = 130/1111 (11%)
Query: 324 ILGKLEHVLSQSIKEQTEIYSFLIP-LVRTLV-SKIYELLFMNLHLPSLPFTNGSSSFFE 381
I +LEH L ++ EI+ P L RTL+ S ELL SL SSS E
Sbjct: 1796 ITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGT---SLVCMKSSSSVVE 1852
Query: 382 DFQEYCNSNEWQVYIEKYI-VPYMKQYE-----AHTFYDGHENMALYWKDCYEALMVNMH 435
C S EWQ I+K + +++ + T D +A EA +
Sbjct: 1853 LVMLLC-SQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVA------NEAEFILSR 1905
Query: 436 KRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRW--KAIQLYLT 493
+R E +F+ L + ++ R++ +++++ + T + K I + LT
Sbjct: 1906 QR-AEDIHRHAEFESLCAQ-YSADKREDEKMCDHLIRAAKYRDHVTATQLIQKIINI-LT 1962
Query: 494 CERGPWAKRK-QNPIH-WKLANVENYSRMRLKLVPNYNFKTHEEASA-----------LR 540
+ G W P+ W+L E+ R R + V N TH EA+ LR
Sbjct: 1963 DKHGAWGNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHVCIFKLR 2022
Query: 541 DNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLD---LPEEDITARVNVDEKEEQDQKEK 597
+N S+ + + +L + + ++ + + L E D +VDEK+ ++
Sbjct: 2023 EN-----SKATDEDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEKDLENLAGP 2077
Query: 598 LVLMEDCELITIIDVIPGRLEITTQHIYFY----DGSIEKEDGV------GFDFKWPHSQ 647
+ L +L+ V+ G L +T+ +YF D + +K D G KW ++
Sbjct: 2078 VSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTE 2137
Query: 648 IREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGS------ 701
IR I RRY L+ +ALEIF ++ NF K L + +G
Sbjct: 2138 IRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRI 2197
Query: 702 --RSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEE 759
SP++LFKAS +TQ+W +REISNF+YL+ +NT+AGR+YNDL QYPVFPW++ +Y SEE
Sbjct: 2198 SLASPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEE 2257
Query: 760 LDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYL 819
LDL P FRDLSKPIG +N K A E+YE++ED + KFHYGTHYS ++ V+ +L
Sbjct: 2258 LDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQ--VPKFHYGTHYSTASFVLAWL 2315
Query: 820 IRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQN 879
+R+EPFTT + LQ G+FD ADR F SI W+ + D+KELIPEF+Y PE N N
Sbjct: 2316 LRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFN 2375
Query: 880 QFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRG 939
+NLG + +V+DV LP WAK++E+F++ +R ALESE+VS LH+WIDLIFGYKQ+G
Sbjct: 2376 NYNLGVMD-DGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQG 2434
Query: 940 PAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEE 999
P AV ALNVFYY +YEGAV+L+++TD R+A+E I +FGQTP QLL EPHPPR SA
Sbjct: 2435 PEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSA-- 2492
Query: 1000 AVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFMSQGS-PEL-- 1056
+ S L F + D I +LK P N + ++ + P L
Sbjct: 2493 -------MQVSPL----------MFTDKAQQDVIMVLK--FPSNSPVTHVAANTQPGLAT 2533
Query: 1057 --LITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKT------------QRSINGS 1102
+IT++ N + + W N+ + ++DQ P +R I
Sbjct: 2534 PAVITVTANRLFAVNKW----HNLPAHQGAVQDQPYQLPVEIDPLIASNTGMHRRQITDL 2589
Query: 1103 FAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLA--TD 1160
+++ S+ FV++ D + + G+WD S +V S G++I + H D+VTCLA
Sbjct: 2590 LDQSIQVHSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSES 2649
Query: 1161 YCG--IHLISGSRDTTCMIW----QITQQGGVPVGLASKPFQILYGHTNEVLSVGISTEL 1214
Y G +++SGSRD T ++W + + G P + P IL GH EV + EL
Sbjct: 2650 YIGGNCYILSGSRDATLLLWYWNGKCSGIGDNPGSETAAPRAILTGHDYEVTCAAVCAEL 2709
Query: 1215 DMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTT 1274
+ +SGS++G +IH++ G +RTL P E+ L + + S EGH V++
Sbjct: 2710 GLVLSGSQEGPCLIHSM-NGDLLRTLEGP-ENCLKPKL--IQASREGHCVIF-------- 2757
Query: 1275 LKDKNALHLFSINGKYLGSQILKEQVSDICII--GEHIVTGSIQGFLSIRDLHSLNLSIN 1332
+ FS+NGK + + + I + G++++TG +G + +R + L
Sbjct: 2758 -YENGLFCTFSVNGKLQATMETDDNIRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFA 2816
Query: 1333 PLAMRLPIHCVCVTKEYSHILVGLEDGKLIV 1363
I + ++ + I+ G+ G +++
Sbjct: 2817 YPGCDAGIRAMALSYDQRCIISGMASGSIVL 2847
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 395 bits (1015), Expect = e-109
Identities = 251/682 (36%), Positives = 347/682 (50%), Gaps = 91/682 (13%)
Query: 570 EDKLDLPEEDITARVNVDEKEEQDQKEKLVLMED---------CELITIIDVIPGRLEIT 620
E+ + ++ I +++E+E+ D L L+E+ C + +D G L
Sbjct: 2499 EENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFG 2558
Query: 621 TQHIYFYDGSIEKEDGVGFDFK----------------------------WPHSQIREIH 652
+H Y DG D + + + I+E+H
Sbjct: 2559 KEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVH 2618
Query: 653 LRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKIYSRLLSL-----HSPNSYYGSRSPQEL 707
RRY L+ A+E+F D NY L F+K +RNK+Y R L++ S S G R +
Sbjct: 2619 KRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSV 2678
Query: 708 FKASGL----------TQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTS 757
+ SGL TQ+W EISNF YL+ +NT+AGR+YNDL QYPVFPWIL DY S
Sbjct: 2679 EQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDS 2738
Query: 758 EELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMH 817
EE+DL NP FR+L+KP+G ++ +++Y+++EDP G +HYGTHYS++ V
Sbjct: 2739 EEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVAS 2798
Query: 818 YLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATW-QALMDNPYDVKELIPEFFYFPEFLE 876
YL+R+EPFT + ++LQ G FD ADR FHS+ W A N DVKELIPEFFY PEFL
Sbjct: 2799 YLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLF 2858
Query: 877 NQNQFNLGRLQISKELVNDVILPKWAK-SAEDFIYKHRKALESEYVSAHLHEWIDLIFGY 935
N N F+LG Q +L DVILP WAK +FI HR+ALE +YVSAHLHEWIDLIFGY
Sbjct: 2859 NSNNFDLGCKQNGTKL-GDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGY 2917
Query: 936 KQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPP-- 993
KQ+GPAAVEA+NVF++ YEG VD+ + D + A G INNFGQ P QL K+PHPP
Sbjct: 2918 KQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKR 2977
Query: 994 ---RLSAEEAVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQY----R 1046
RL+ + A TS F HL L+ P+ + P Q +
Sbjct: 2978 VRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSL-------TPVKELKEPVGQIVCTDK 3030
Query: 1047 SFMSQGSPELLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPG 1106
++ ++LI + N T W Y T+ D+ +T +
Sbjct: 3031 GILAVEQNKVLIPPTWN---KTFAW-GYADLSCRLGTYESDKAMT----------VYECL 3076
Query: 1107 LEITSKLFVVSHDAKLLFSAG------YWDNSIQVMSLTKGKIISHIIRHMDIVTCLATD 1160
E L + + KL+ + G W+ + ++ H D VTC
Sbjct: 3077 SEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATAS 3136
Query: 1161 YCGIHLISGSRDTTCMIWQITQ 1182
++SGSRD TC+IW + +
Sbjct: 3137 LAYHIIVSGSRDRTCIIWDLNK 3158
>gi|31543297 neutral sphingomyelinase (N-SMase) activation associated
factor isoform 1 [Homo sapiens]
Length = 917
Score = 336 bits (862), Expect = 8e-92
Identities = 255/794 (32%), Positives = 396/794 (49%), Gaps = 73/794 (9%)
Query: 582 ARVNVDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDF 641
AR + D+ Q+ EKL + E++T + PG + IT ++YF + + V
Sbjct: 178 ARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITL 237
Query: 642 KWPHSQIREIHLRRYNLRRSALEIFHVDQ---SNYFLNF-KKEVRNKIYSRLLSLHSPNS 697
+ +R I+ RR+ L LE+F + S+ +L F + + R+ +Y + +
Sbjct: 238 Q----DVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIAT------ 287
Query: 698 YYGSRSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTS 757
Y E S + Q W +SN+ YL+ +N +A R+ NDL+QYPVFPWI+ DY+S
Sbjct: 288 -YLEHHVAEHTAESYMLQ-WQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSS 345
Query: 758 EELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMH 817
ELDL+NP FRDLSKP+G +N++ + + +Y+ +P KF YG+HYS+ V+
Sbjct: 346 SELDLSNPGTFRDLSKPVGALNKERLERLLTRYQEMPEP-----KFMYGSHYSSPGYVLF 400
Query: 818 YLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFP-EFLE 876
YL+R+ P L LQ+GRFD ADR F+SI TW+ +D D KELIPEF+ FL
Sbjct: 401 YLVRIAPEYMLC--LQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYGDDVSFLV 458
Query: 877 NQNQFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYK 936
N + +LG+ Q ++V+DV LP WA S EDF+ K + ALES YVS HLHEWIDLIFGYK
Sbjct: 459 NSLKLDLGKRQ-GGQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYK 517
Query: 937 QRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLS 996
Q+G AV A NVF+ +YEG VDL+++ D E+ A+ I FGQTP QL PHP R++
Sbjct: 518 QKGSDAVGAHNVFHPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRIT 577
Query: 997 AEEAVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPEL 1056
+ + TS+ N + F + + L I K Q
Sbjct: 578 P----KFKSLSQTSSYNASMADSPGEESFEDLTEESKTLAWNNITKLQLHEHYK------ 627
Query: 1057 LITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTN-PKTQRSINGSFAPGLEITSKLFV 1115
I V G + RN S+ FT +D T+ K + + S + S +
Sbjct: 628 ---IHKEAVTG----ITVSRNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLL 680
Query: 1116 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1175
+ DA ++ S+ WDN++ S+ G+ ++ H D V+ + + L S S D+T
Sbjct: 681 LPGDATVITSS--WDNNVYFYSIAFGRRQDTLMGHDDAVSKIC--WHDNRLYSASWDSTV 736
Query: 1176 MIWQITQQGGVPV---GLASKPFQIL--YGHTNEVLSVGISTELDMAVSGSRDGTVIIHT 1230
+W GVP G F +L H V ++ ++ + VSG+++GTV I
Sbjct: 737 KVW-----SGVPAEMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWD 791
Query: 1231 IQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKY 1290
+ M + PC S + + + A S + V+ + T+ L++ +
Sbjct: 792 LTTATLMHQI--PCHSGI---VCDTAFSPDSRHVLSTGTD--------GCLNVIDVQTGM 838
Query: 1291 LGSQILKEQVSDICII--GEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKE 1348
L S + ++ C + G +++GS G L + DL +S + C+ + ++
Sbjct: 839 LISSMTSDE-PQRCFVWDGNSVLSGSQSGELLVWDLLGAKISERIQGHTGAVTCIWMNEQ 897
Query: 1349 YSHILVGLEDGKLI 1362
S I+ G ED ++I
Sbjct: 898 CSSIITGGEDRQII 911
>gi|221625547 neutral sphingomyelinase (N-SMase) activation associated
factor isoform 2 [Homo sapiens]
Length = 948
Score = 336 bits (862), Expect = 8e-92
Identities = 255/794 (32%), Positives = 396/794 (49%), Gaps = 73/794 (9%)
Query: 582 ARVNVDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDF 641
AR + D+ Q+ EKL + E++T + PG + IT ++YF + + V
Sbjct: 209 ARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITL 268
Query: 642 KWPHSQIREIHLRRYNLRRSALEIFHVDQ---SNYFLNF-KKEVRNKIYSRLLSLHSPNS 697
+ +R I+ RR+ L LE+F + S+ +L F + + R+ +Y + +
Sbjct: 269 Q----DVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIAT------ 318
Query: 698 YYGSRSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTS 757
Y E S + Q W +SN+ YL+ +N +A R+ NDL+QYPVFPWI+ DY+S
Sbjct: 319 -YLEHHVAEHTAESYMLQ-WQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSS 376
Query: 758 EELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMH 817
ELDL+NP FRDLSKP+G +N++ + + +Y+ +P KF YG+HYS+ V+
Sbjct: 377 SELDLSNPGTFRDLSKPVGALNKERLERLLTRYQEMPEP-----KFMYGSHYSSPGYVLF 431
Query: 818 YLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFP-EFLE 876
YL+R+ P L LQ+GRFD ADR F+SI TW+ +D D KELIPEF+ FL
Sbjct: 432 YLVRIAPEYMLC--LQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYGDDVSFLV 489
Query: 877 NQNQFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYK 936
N + +LG+ Q ++V+DV LP WA S EDF+ K + ALES YVS HLHEWIDLIFGYK
Sbjct: 490 NSLKLDLGKRQ-GGQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYK 548
Query: 937 QRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLS 996
Q+G AV A NVF+ +YEG VDL+++ D E+ A+ I FGQTP QL PHP R++
Sbjct: 549 QKGSDAVGAHNVFHPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRIT 608
Query: 997 AEEAVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPEL 1056
+ + TS+ N + F + + L I K Q
Sbjct: 609 P----KFKSLSQTSSYNASMADSPGEESFEDLTEESKTLAWNNITKLQLHEHYK------ 658
Query: 1057 LITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTN-PKTQRSINGSFAPGLEITSKLFV 1115
I V G + RN S+ FT +D T+ K + + S + S +
Sbjct: 659 ---IHKEAVTG----ITVSRNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLL 711
Query: 1116 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1175
+ DA ++ S+ WDN++ S+ G+ ++ H D V+ + + L S S D+T
Sbjct: 712 LPGDATVITSS--WDNNVYFYSIAFGRRQDTLMGHDDAVSKIC--WHDNRLYSASWDSTV 767
Query: 1176 MIWQITQQGGVPV---GLASKPFQIL--YGHTNEVLSVGISTELDMAVSGSRDGTVIIHT 1230
+W GVP G F +L H V ++ ++ + VSG+++GTV I
Sbjct: 768 KVW-----SGVPAEMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWD 822
Query: 1231 IQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKY 1290
+ M + PC S + + + A S + V+ + T+ L++ +
Sbjct: 823 LTTATLMHQI--PCHSGI---VCDTAFSPDSRHVLSTGTD--------GCLNVIDVQTGM 869
Query: 1291 LGSQILKEQVSDICII--GEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKE 1348
L S + ++ C + G +++GS G L + DL +S + C+ + ++
Sbjct: 870 LISSMTSDE-PQRCFVWDGNSVLSGSQSGELLVWDLLGAKISERIQGHTGAVTCIWMNEQ 928
Query: 1349 YSHILVGLEDGKLI 1362
S I+ G ED ++I
Sbjct: 929 CSSIITGGEDRQII 942
>gi|191252801 WDFY family member 4 [Homo sapiens]
Length = 3184
Score = 325 bits (833), Expect = 2e-88
Identities = 280/982 (28%), Positives = 444/982 (45%), Gaps = 129/982 (13%)
Query: 416 HENMALYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLR-YNNMLKQL 474
H + W + M M R + E K + +E + R+ ++ Y + +++
Sbjct: 2190 HHSKVTLWSGSLSSAMKLMPGRQAKDPECKTEDFVSCIENYRRRGQELYASLYKDHVQRR 2249
Query: 475 SSQQLATLRRWKAIQLYLTCERGPWAKRKQNP--IHWKLANVENYSRMRLKL-----VPN 527
+ W IQ L E G W++ ++ W+L E +RMR ++ +
Sbjct: 2250 KCGNIKAANAWARIQEQLFGELGLWSQGEETKPCSPWELDWREGPARMRKRIKRLSPLEA 2309
Query: 528 YNFKTHEEASALRDNLGIQHSQPSSDTLLLEVVKQ----------------VKVSDMVED 571
+ H+E+ D++ +++ + L E + + S ED
Sbjct: 2310 LSSGRHKESQDKNDHISQTNAENQDELTLREAEGEPDEVGVDCTQLTFFPALHESLHSED 2369
Query: 572 KLDLPEEDITARVNVDEKEEQDQKEKLVLMED-----------------CELITII---D 611
L+L E + +KE+ QK LV+++ CE T+ D
Sbjct: 2370 FLELCRERQVILQELLDKEKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGD 2429
Query: 612 VIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHS--QIREIHLRRYNLRRSALEIFHVD 669
V R ++ F K+ HS +RE+ R+ L+ ALEIF +
Sbjct: 2430 VYCTRHCLSNISDPFIFNLCSKDRSTDHYSCQCHSYADMRELRQARFLLQDIALEIFFHN 2489
Query: 670 QSNYFLNFKKEVRNKIYSRLLSLH-SPNSYYGSRSPQELFKASG----LTQKWVNREISN 724
+ FL F R+K + S S S L + G + QKW R+ISN
Sbjct: 2490 GYSKFLVFYNNDRSKAFKSFCSFQPSLKGKATSEDTLSLRRYPGSDRIMLQKWQKRDISN 2549
Query: 725 FDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNEKNAK 784
F+YL+ +NT AGRT ND QYPVFPW+L DYTSE L+L NP +FRDLSKP+G ++
Sbjct: 2550 FEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRDLSKPMGAQTKERKL 2609
Query: 785 AMREKYENFEDPMGTID-KFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQ 843
++++ E G + + HY THYS++ V YL+R+ PFT LQ G FD ADR
Sbjct: 2610 KFIQRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCALQGGSFDVADRM 2669
Query: 844 FHSIPATWQ-ALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPKWA 902
FHS+ +TW+ A +N DV+EL PEFFY PEFL N N G +Q ++ DV LP WA
Sbjct: 2670 FHSVKSTWESASRENMSDVRELTPEFFYLPEFLTNCNGVEFGCMQ-DGTVLGDVQLPPWA 2728
Query: 903 KS-AEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLD 961
FI HRKALES++VSA+LH WIDLIFGYKQ+GPAAV+A+N+F+ Y +DL
Sbjct: 2729 DGDPRKFISLHRKALESDFVSANLHHWIDLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLS 2788
Query: 962 ALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPEL 1021
++TD + + G ++NFGQ P QL +PHP R +A + + P K ++ ++L H P+
Sbjct: 2789 SITDPLIKSTILGFVSNFGQVPKQLFTKPHPARTAAGKPL--PGKDVSTPVSLPGH-PQP 2845
Query: 1022 KSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISNY 1081
+ ++ + + T+ K+ Y + SP+ I +++ T
Sbjct: 2846 FFYSLQSLRPS----QVTV-KDMYLFSLGSESPKGAI----GHIVSTE---------KTI 2887
Query: 1082 FTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKG 1141
+++ + P R+ FS G+ D S + S
Sbjct: 2888 LAVERNKVLLPPLWNRT-------------------------FSWGFDDFSCCLGSYGSD 2922
Query: 1142 KIISHIIRHMDIVTCL-ATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYG 1200
K++ CL A +++ T +W+++ G P GL + Q LYG
Sbjct: 2923 KVLMTFENLAAWGRCLCAVCPSPTTIVTSGTSTVVCVWELSMTKGRPRGLRLR--QALYG 2980
Query: 1201 HTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWE 1260
HT V + S + VSGS+D T I+ + ++ L E +TI +++
Sbjct: 2981 HTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVS---- 3036
Query: 1261 GHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQIL----KEQVSDICII-------GEH 1309
G IV + L L+++NG+ L S + ++ C++ +
Sbjct: 3037 GTIVSCAGAH----------LSLWNVNGQPLASITTAWGPEGAITCCCLMEGPAWDTSQI 3086
Query: 1310 IVTGSIQGFLSIRDLHSLNLSI 1331
I+TGS G + + + +S+
Sbjct: 3087 IITGSQDGMVRVWKTEDVKMSV 3108
>gi|54292123 lysosomal trafficking regulator [Homo sapiens]
Length = 3801
Score = 324 bits (831), Expect = 3e-88
Identities = 248/790 (31%), Positives = 382/790 (48%), Gaps = 80/790 (10%)
Query: 479 LATLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASA 538
L+ R W+ + LT +R W P W+L E +R R +L Y T
Sbjct: 2917 LSASRHWQELIQQLTHDRAVWYDPIYYPTSWQLDPTEGPNRERRRLQRCY--LTIPNKYL 2974
Query: 539 LRDNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITAR-VNVDEKEEQDQKEK 597
LRD + + L E S V+DK + R ++V E +
Sbjct: 2975 LRDRQKSEDVVKPPLSYLFEDKTHSSFSSTVKDKAASESIRVNRRCISVAPSRETAGE-- 3032
Query: 598 LVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYN 657
+L+ C + + D +E ++ G +E F W + +I+E+H R +
Sbjct: 3033 -LLLGKCGMYFVEDNASDTVESSS-----LQGELEPAS-----FSWTYEEIKEVHKRWWQ 3081
Query: 658 LRRSALEIFHVDQSNYFLNFKK-EVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQK 716
LR +A+EIF + L F +VR+ +Y +L+ + PN E + LT
Sbjct: 3082 LRDNAVEIFLTNGRTLLLAFDNTKVRDDVYHNILTNNLPNLL-------EYGNITALTNL 3134
Query: 717 WVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIG 776
W +I+NF+YL +N AGR++NDL QYPVFP+IL DY SE LDLN+ ++R+LSKPI
Sbjct: 3135 WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIA 3194
Query: 777 VVNEKNAKAMREKYENFE----------DPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFT 826
V ++ + Y+ E DPM + +HYG+HYSNS V+H+L+R+ PFT
Sbjct: 3195 VQYKEKEDRYVDTYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFT 3254
Query: 827 TLHIQLQSGRFDCADRQFHSIPATWQ-ALMDNPYDVKELIPEFFYFPEFLENQNQFNLGR 885
+ + Q FD DR FHS TW+ + ++ DVKELIPEFFY PEFL N+ F+ G
Sbjct: 3255 KMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGV 3314
Query: 886 LQISKELVNDVILPKWAKS-AEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVE 944
Q + E VN V LP WA++ FI HR+ALES+YVS ++ +WIDL+FGYKQ+G A+V+
Sbjct: 3315 RQ-NGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQ 3373
Query: 945 ALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV--Q 1002
A+NVF+ +Y G +D+ A+ D +R+ALE MI +GQTP QL H R A+ + +
Sbjct: 3374 AINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSRPGAKLNIEGE 3432
Query: 1003 KPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFM-SQGSPELLITIS 1061
P + F+ E ++ I+ PL + I ++ ++ S +P ++ S
Sbjct: 3433 LPAAVGLLVQFAFRETREQ----VKEITYPSPL--SWIKGLKWGEYVGSPSAPVPVVCFS 3486
Query: 1062 MNY--------VIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKL 1113
+ + T RN T+ K+Q V RS+N +
Sbjct: 3487 QPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGV------RSMNST----------- 3529
Query: 1114 FVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHI--IRHMDIVTCL-ATDYCGIHLISGS 1170
+ S GY DN +++ S ++ I + + +C D C L +GS
Sbjct: 3530 ---DIQWSAILSWGYADNILRLKSKQSEPPVNFIQSSQQYQVTSCAWVPDSC--QLFTGS 3584
Query: 1171 RDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHT 1230
+ + P + + LYGHT E+ S+ + + +S SRDGT II
Sbjct: 3585 KCGVITAYTNRFTSSTPSEIEMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWD 3644
Query: 1231 IQKGQYMRTL 1240
+ + Y+++L
Sbjct: 3645 LNRLCYVQSL 3654
>gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 102 bits (254), Expect = 3e-21
Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
Query: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
K +N K K + YE G + H H S+ + Y + T
Sbjct: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
Query: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
Query: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
Query: 948 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 1001
V + L D A G++ QL +PHP RL+ A+
Sbjct: 564 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598
Score = 31.2 bits (69), Expect = 7.3
Identities = 49/208 (23%), Positives = 75/208 (36%), Gaps = 25/208 (12%)
Query: 1128 YWDNSIQVMSLTKGKIISHIIR------HMDIVTCLATDYCGIHLISGSRDTTCMIWQIT 1181
YW I V S H IR H V C+A +SGS+D T +W +
Sbjct: 1620 YWQYEIGV-SQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLY 1678
Query: 1182 QQGGVPVGLASKPFQILY-GHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
G G + +++Y H V VG V S DG V + G+ +RT+
Sbjct: 1679 NYGD---GTSETAPRLVYTQHRKSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTV 1733
Query: 1241 RP-----PCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1295
P P + + P+ +I+ + ST + H F + G +
Sbjct: 1734 EPLDSRVPLTAVAVMPAPHTSIT----MASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLV 1789
Query: 1296 LKEQVSDICIIGEHIVTGSIQGFLSIRD 1323
+S G +V G GF+ + D
Sbjct: 1790 RALAISP---SGRSVVAGFSSGFMVLLD 1814
>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 2240
Score = 102 bits (254), Expect = 3e-21
Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 647 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 699
Query: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
K +N K K + YE G + H H S+ + Y + T
Sbjct: 700 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 758
Query: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 759 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 807
Query: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 808 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 862
Query: 948 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 1001
V + L D A G++ QL +PHP RL+ A+
Sbjct: 863 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 897
Score = 31.2 bits (69), Expect = 7.3
Identities = 49/208 (23%), Positives = 75/208 (36%), Gaps = 25/208 (12%)
Query: 1128 YWDNSIQVMSLTKGKIISHIIR------HMDIVTCLATDYCGIHLISGSRDTTCMIWQIT 1181
YW I V S H IR H V C+A +SGS+D T +W +
Sbjct: 1919 YWQYEIGV-SQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLY 1977
Query: 1182 QQGGVPVGLASKPFQILY-GHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
G G + +++Y H V VG V S DG V + G+ +RT+
Sbjct: 1978 NYGD---GTSETAPRLVYTQHRKSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTV 2032
Query: 1241 RP-----PCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1295
P P + + P+ +I+ + ST + H F + G +
Sbjct: 2033 EPLDSRVPLTAVAVMPAPHTSIT----MASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLV 2088
Query: 1296 LKEQVSDICIIGEHIVTGSIQGFLSIRD 1323
+S G +V G GF+ + D
Sbjct: 2089 RALAISP---SGRSVVAGFSSGFMVLLD 2113
>gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 102 bits (254), Expect = 3e-21
Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
Query: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
K +N K K + YE G + H H S+ + Y + T
Sbjct: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
Query: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
Query: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
Query: 948 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 1001
V + L D A G++ QL +PHP RL+ A+
Sbjct: 564 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598
Score = 31.2 bits (69), Expect = 7.3
Identities = 49/208 (23%), Positives = 75/208 (36%), Gaps = 25/208 (12%)
Query: 1128 YWDNSIQVMSLTKGKIISHIIR------HMDIVTCLATDYCGIHLISGSRDTTCMIWQIT 1181
YW I V S H IR H V C+A +SGS+D T +W +
Sbjct: 1620 YWQYEIGV-SQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLY 1678
Query: 1182 QQGGVPVGLASKPFQILY-GHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
G G + +++Y H V VG V S DG V + G+ +RT+
Sbjct: 1679 NYGD---GTSETAPRLVYTQHRKSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTV 1733
Query: 1241 RP-----PCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI 1295
P P + + P+ +I+ + ST + H F + G +
Sbjct: 1734 EPLDSRVPLTAVAVMPAPHTSIT----MASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLV 1789
Query: 1296 LKEQVSDICIIGEHIVTGSIQGFLSIRD 1323
+S G +V G GF+ + D
Sbjct: 1790 RALAISP---SGRSVVAGFSSGFMVLLD 1814
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/196 (24%), Positives = 87/196 (44%), Gaps = 24/196 (12%)
Query: 1125 SAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQG 1184
+ G +D + ++ S+ GK H + CL+ + + +GS DTT +W I Q
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI--QN 208
Query: 1185 GVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPC 1244
G V L GH+ E++S+ +T D ++GS D TV++ G+ + L C
Sbjct: 209 GEEV-------YTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHC 261
Query: 1245 ESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQI-LKEQVSDI 1303
I + + +W+ +++ S ++ L D + NGK + + +++ D
Sbjct: 262 AE-----ISSASFNWDCSLILTGSMDKTCKLWD-------ATNGKCVATLTGHDDEILDS 309
Query: 1304 CI--IGEHIVTGSIQG 1317
C G+ I T S G
Sbjct: 310 CFDYTGKLIATASADG 325
Score = 49.7 bits (117), Expect = 2e-05
Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 1124 FSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLA-TDYCGIHLISGSRDTTCMIWQITQ 1182
F G +D + ++ G+ ++ + H ++V +A + G + +GS D TC +W +
Sbjct: 107 FITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVE- 165
Query: 1183 QGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLR 1241
K + GHT E++ + + + + +GS D T + IQ G+ + TLR
Sbjct: 166 --------TGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLR 216
Score = 48.9 bits (115), Expect = 3e-05
Identities = 57/231 (24%), Positives = 98/231 (42%), Gaps = 31/231 (13%)
Query: 1042 KNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVT--NPKTQRSI 1099
+N + +G +I++S N T G DR I+ F D TV + T R +
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFN----TSG----DRIITGSF----DHTVVVWDADTGRKV 254
Query: 1100 NGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLAT 1159
N EI+S F + D L+ + G D + ++ T GK ++ + H D +
Sbjct: 255 NILIGHCAEISSASF--NWDCSLILT-GSMDKTCKLWDATNGKCVATLTGHDDEILDSCF 311
Query: 1160 DYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVS 1219
DY G + + S D T I+ + K L GH E+ + + + + ++
Sbjct: 312 DYTGKLIATASADGTARIFSAATR---------KCIAKLEGHEGEISKISFNPQGNHLLT 362
Query: 1220 GSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTE 1270
GS D T I Q GQ ++ L + I + A +++G+IV+ S +
Sbjct: 363 GSSDKTARIWDAQTGQCLQVLEGHTDE-----IFSCAFNYKGNIVITGSKD 408
Score = 46.6 bits (109), Expect = 2e-04
Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 10/108 (9%)
Query: 1118 HDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMI 1177
+ KL+ +A D + ++ S K I+ + H ++ ++ + G HL++GS D T I
Sbjct: 313 YTGKLIATASA-DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARI 371
Query: 1178 WQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGT 1225
W Q G + Q+L GHT+E+ S + + ++ ++GS+D T
Sbjct: 372 WD-AQTG--------QCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNT 410
Score = 40.4 bits (93), Expect = 0.012
Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 1123 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQ 1182
L + G D + ++ + G+ + + H + L+ + G +I+GS D T ++W
Sbjct: 191 LVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD- 249
Query: 1183 QGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
+ IL GH E+ S + + + ++GS D T + G+ + TL
Sbjct: 250 --------TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATL 299
Score = 37.0 bits (84), Expect = 0.13
Identities = 40/176 (22%), Positives = 71/176 (40%), Gaps = 21/176 (11%)
Query: 1150 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG 1209
H+ +T +A + G I+GS D TC +W + + L GH N V ++
Sbjct: 91 HILPLTNVALNKSGSCFITGSYDRTCKLWDTA---------SGEELNTLEGHRNVVYAIA 141
Query: 1210 ISTEL-DMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSS 1268
+ D +GS D T + +++ G+ T R I L+ + + +V S
Sbjct: 142 FNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAE-----IVCLSFNPQSTLVATGS 196
Query: 1269 TEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLSIRD 1323
+ L D +N ++++ G L S G+ I+TGS + + D
Sbjct: 197 MDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTS-----GDRIITGSFDHTVVVWD 247
Score = 34.7 bits (78), Expect = 0.66
Identities = 16/53 (30%), Positives = 28/53 (52%)
Query: 1127 GYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQ 1179
G D + ++ G+ + + H D + A +Y G +I+GS+D TC IW+
Sbjct: 363 GSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 50.1 bits (118), Expect = 2e-05
Identities = 40/136 (29%), Positives = 57/136 (41%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N + +S+ S S D S DS SDS + S S S + S SD
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 123 RESSITNDMGFSDDFS 138
+SS +D S D S
Sbjct: 853 SDSSNRSDSSNSSDSS 868
Score = 46.6 bits (109), Expect = 2e-04
Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 1/136 (0%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D ++++ SSD + D S DS+ DSS
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 64 SFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S +S N + +S+ S S D S DS SDS + S S S S+ S +
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 983 SDSSDSSDSSDSSDSS 998
Score = 45.4 bits (106), Expect = 4e-04
Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 3/141 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S NS + +D + + ++ SSD S + DS+ DSS
Sbjct: 588 SDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS 647
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S+N + SN S+ S DS + SDS S S S S + + S SD
Sbjct: 648 SDSSDNSDSSDSSNSSNSS---DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S +D S D S S +
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSD 725
Score = 44.3 bits (103), Expect = 8e-04
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 2/143 (1%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + + D+ +SD S S+N S + S + +S DS+ +SS
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVHS 121
S S N + SN S S + DS + SDS S DS S+ S S S S +S
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 122 DRESSITNDMGFSDDFSLLESQE 144
S+ ++ SD +S +
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSD 1041
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/135 (32%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D S S+N S S + S DS+ DSS
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S N + +S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSS--DSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSS- 1067
Query: 124 ESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1068 DSSDSSDSSDSSDSS 1082
Score = 43.1 bits (100), Expect = 0.002
Identities = 36/141 (25%), Positives = 60/141 (42%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
++ + S D+K +S + + + S++ S+ S + S DS+ DSS
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + S+ S S D DS + S+S S DS S+ S S S S S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S+ ++ SD + +S +
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSD 769
Score = 43.1 bits (100), Expect = 0.002
Identities = 41/138 (29%), Positives = 58/138 (42%), Gaps = 2/138 (1%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S N + S+ S S D S DS + SDS + S S S + + S S
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 122 D-RESSITNDMGFSDDFS 138
D ESS ++D S D S
Sbjct: 1146 DSSESSDSSDSSDSSDSS 1163
Score = 43.1 bits (100), Expect = 0.002
Identities = 44/138 (31%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD E S S+N S S + S DS+ DSS
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS E SDS S DS S+ S S S S +
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSS--DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1180 SS-DSSDSSDSSDSSDSS 1196
Score = 42.0 bits (97), Expect = 0.004
Identities = 45/150 (30%), Positives = 67/150 (44%), Gaps = 10/150 (6%)
Query: 3 DNDKNMSTEDTKKNSDEK-------TDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFP 55
++D + ST DT NSD D +K S + SSD S + +S DS+
Sbjct: 511 EDDDSDSTSDTN-NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569
Query: 56 EDSSVGELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTK 115
+ S S + + S+ S S + DS + SDS S DS S+ S +S+K
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS-SDSSDSSDSSDSKSDSSK 628
Query: 116 SFSVHSDRES-SITNDMGFSDDFSLLESQE 144
S S SD +S S ++D SD +S +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Score = 41.6 bits (96), Expect = 0.005
Identities = 43/142 (30%), Positives = 58/142 (40%), Gaps = 11/142 (7%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD K+D K S + SSD S D S DSN+ DSS
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSK-----SESDSSDSDSKSD--SSDSNS----SDSSDNS 654
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N S+ S S D S S S DS S+ S S S S SD
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S ++ SD + +S +
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSD 736
Score = 41.2 bits (95), Expect = 0.007
Identities = 42/141 (29%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D + + ++ SSD S + +S DS+ DSS
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSDSSD 1074
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + E S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSS--DSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD ES +
Sbjct: 1132 SSDSSDSSNSSDSSDSSESSD 1152
Score = 41.2 bits (95), Expect = 0.007
Identities = 44/139 (31%), Positives = 59/139 (42%), Gaps = 4/139 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S+N S S E S DS+ DSS
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSV 119
S S + S+ S S D S DS + SDS S DS S+ S S S S
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 120 HSDRESSITNDMGFSDDFS 138
S+ ESS ++D S D S
Sbjct: 1230 DSN-ESSDSSDSSDSSDSS 1247
Score = 40.8 bits (94), Expect = 0.009
Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 2/136 (1%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ ++ ++ D +SD + S S+N S S + +S DS+ + S
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ + S+ S S DS + SDS S DS S+ S S S S S
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS-SNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1041 -DSSDSSDSSDSSDSS 1055
Score = 40.8 bits (94), Expect = 0.009
Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 3/142 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S +S + SDS S DS S+ S S S S S
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSS--ESSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSS 1115
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSD 1137
Score = 40.8 bits (94), Expect = 0.009
Identities = 36/145 (24%), Positives = 57/145 (39%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S + S S DS S+ S S S S +S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 123 RESSITNDMGFSDDFSLLESQERCE 147
S ++ SD + +S + E
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSE 1149
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/136 (30%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ ++ + D+ +SD + S S++ S S + +S DS+ DSS
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + E S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSS--DSSDSSDS-SDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1197 -DSSDSSDSSDSSDSS 1211
Score = 40.4 bits (93), Expect = 0.012
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 1/137 (0%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+D + S++ + NS + S S+N S S + +S DS+ +SS
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S + + +S+ S+ S + S DS SDS + S S S +S+ S +
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 122 DRESSITNDMGFSDDFS 138
+SS +++ S D S
Sbjct: 829 SSDSSDSSNSSDSSDSS 845
Score = 40.4 bits (93), Expect = 0.012
Identities = 40/145 (27%), Positives = 61/145 (42%), Gaps = 3/145 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S++ S S + +S DS+ DSS
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSV 119
S S + + +S+ S S D S DS SDS S+ DS S+ S S S S
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 120 HSDRESSITNDMGFSDDFSLLESQE 144
S S +N SD +S +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSD 1194
Score = 40.4 bits (93), Expect = 0.012
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ ++SD + S S++ S S + +S DS+ DSS
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS + SDS ++ DS S+ S S S S
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254
Query: 121 SDRESSITNDMGFSDD 136
S S T+D D
Sbjct: 1255 SSDSSDSTSDSNDESD 1270
Score = 40.0 bits (92), Expect = 0.016
Identities = 36/147 (24%), Positives = 56/147 (38%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + S+ D+ +SD + S S++ S S S SN+ DSS
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N + S+ S S D S S S DS S+ S S + S +S
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 123 RESSITNDMGFSDDFSLLESQERCEEE 149
S +N S+ +S + + +
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Score = 39.7 bits (91), Expect = 0.021
Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S NS + +D ++ + ++ SSD S E +S DS+ DS +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD--SNESSNSSDSSDSSNSSDSDSSDS 908
Query: 64 SFKSENQEEFWHSN---PSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVH 120
S S++ + S+ S+ S + + DS SDS S S S + + S
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 121 SDRESSITNDMGFSDDFS 138
SD SS ++D S D S
Sbjct: 969 SDSNSSDSSDSSNSSDSS 986
Score = 39.7 bits (91), Expect = 0.021
Identities = 34/141 (24%), Positives = 58/141 (41%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
++ N S +S + +D + ++++ SS+ D +S DS+ DSS
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + +S+ S S D S + S + S +S S+ S S S S S
Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSD 1071
Score = 39.7 bits (91), Expect = 0.021
Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S E S DS+ DSS
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS + SDS S DS S+ S S S S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSS--DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1162 SS-DSSDSSDSSDSSDSS 1178
Score = 39.7 bits (91), Expect = 0.021
Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD E S S++ S S + S DS+ DSS
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S DS + SDS S DS S+ S ES+ S
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDS-SDSSDSSDSSDSN-ESSDSSDSSDS 1243
Query: 123 RESSITNDMGFSDDFSLLESQERCEEE 149
+SS ++D S D S S E +
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESD 1270
Score = 39.3 bits (90), Expect = 0.027
Identities = 40/135 (29%), Positives = 58/135 (42%), Gaps = 3/135 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N N + ++ K +S + + + + ++ SSD D S DSN+ DSS +
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS-SDSDSSDSDS 587
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S++ SN S S DS + SDS DS S S + S S SD
Sbjct: 588 SDSSDSDSSD-SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDS 645
Query: 124 ESSITNDMGFSDDFS 138
SS ++D S D S
Sbjct: 646 NSSDSSDNSDSSDSS 660
Score = 39.3 bits (90), Expect = 0.027
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 5/146 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
DN + + ++ +SD + S +S++ S+ S + S +S+ DSS +
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711
Query: 63 LSFKSE----NQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFS 118
S S+ N + SN S S + DS + SDS S DS S+ S S S S
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSSNSSDSSDS 770
Query: 119 VHSDRESSITNDMGFSDDFSLLESQE 144
S S +N +D + +S +
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSD 796
Score = 39.3 bits (90), Expect = 0.027
Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 1/132 (0%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S NS + +D + + ++ SSD + + DS+ DSS
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S S D S + SDS S DS S+ S S S S +
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS-SNSSDSSDSSNSSDSSESSNSSDNSN 934
Query: 124 ESSITNDMGFSD 135
S +N SD
Sbjct: 935 SSDSSNSSDSSD 946
Score = 39.3 bits (90), Expect = 0.027
Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDR-HSLDSNTPLFPEDSSVGE 62
+D + S++ + NS + +D + + ++ SSD D +S DS+ DSS
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 63 LSFKSENQEEFWHSNPSHLSLDLS-GIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S + S+ S S D S DS + SDS + S S S + S S
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 122 D-RESSITNDMGFSDDFS 138
D ESS ++D S D S
Sbjct: 1080 DSSESSDSSDSSNSSDSS 1097
Score = 39.3 bits (90), Expect = 0.027
Identities = 37/141 (26%), Positives = 54/141 (38%), Gaps = 2/141 (1%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D N S NS + +D + + ++ SS+ S + S DS+ DSS
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSNSSDSSNSSD 1026
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S S D S S S DS S+ S S S S S
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSD 1107
Score = 38.9 bits (89), Expect = 0.035
Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 3/143 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S +SD + + +S + ++ SSD S + +S DS+ DSS
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 64 S--FKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S KS++ + S+ S D S +S + SD+ S DS S+ S S S S S
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN-SDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 122 DRESSITNDMGFSDDFSLLESQE 144
S +N SD S E
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSE 700
Score = 38.9 bits (89), Expect = 0.035
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLED---RHSLDSNTPLFPEDSSV 60
+ N S + NS + +D + ++++ SSD D +S DS+ DSS
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837
Query: 61 GELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFS 118
S S + + S+ S+ S + DS + SDS S DS S S S S S
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 119 VH-SDRESSITNDMGFSDDFS 138
+ SD +SS +++ S D S
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSS 918
Score = 38.9 bits (89), Expect = 0.035
Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 4/138 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
++ + + D+ +SD + + +S +S + +S S E +S D++ +SS
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD-SSESSNSSDNSNSSDSSNSSDSS 945
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS- 121
S S N + +S+ S S D S +S + SDS S DS S+ S S S S +S
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 122 -DRESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1005 DSSDSSDSSDSSNSSDSS 1022
Score = 38.9 bits (89), Expect = 0.035
Identities = 41/136 (30%), Positives = 59/136 (43%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + ++ +SD + S S++ S S + S DS+ DSS
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S N + S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSS--DSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1191 -DSSDSSDSSDSSDSS 1205
Score = 38.9 bits (89), Expect = 0.035
Identities = 36/142 (25%), Positives = 54/142 (38%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
++ + + D+ +SD + S S+N S S + S DS+ DSS
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S + S S DS S+ S S S S S
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S ++ SD +S E
Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNE 1233
Score = 38.5 bits (88), Expect = 0.046
Identities = 33/136 (24%), Positives = 55/136 (40%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD S S+N S S S +S+ DSS +
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ S+ S+ S DS + SDS S ++ +S+ S +
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 123 RESSITNDMGFSDDFS 138
+SS +N+ S D S
Sbjct: 880 SDSSDSNESSNSSDSS 895
Score = 38.5 bits (88), Expect = 0.046
Identities = 34/144 (23%), Positives = 56/144 (38%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + ++ ++ + ++ S+ S + +S DS+ DSS
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S S D S S S DS S+ S S S S +S
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 124 ESSITNDMGFSDDFSLLESQERCE 147
S ++ SD +S + E
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSE 1083
Score = 38.5 bits (88), Expect = 0.046
Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 1/136 (0%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S S S DS S+ S S S S S
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1152 -DSSDSSDSSDSSDSS 1166
Score = 38.5 bits (88), Expect = 0.046
Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 1/136 (0%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S+ S + S DS+ DSS
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + S+ S S D S S S DS S+ S S S S S
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1209 -DSSDSSDSSDSSDSS 1223
Score = 38.1 bits (87), Expect = 0.060
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 2/136 (1%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S++ S+ S + S +S+ DSS
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + + SN S S DS + SDS S DS S+ S S S S +S
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1026 -DSSNSSDSSDSSDSS 1040
Score = 38.1 bits (87), Expect = 0.060
Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 3/142 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + +S DS+ DSS +
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS--D 1155
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ + S+ S S + DS + SDS S DS S+ S S S S S
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSS 1214
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S ++ SD ES +
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSD 1236
Score = 37.7 bits (86), Expect = 0.078
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 7/137 (5%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S++ + +S ++D + + ++ SS+ S + S DSN DSS
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN--SSDSSDSSDSNESSNSSDSSDSSN 899
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVHS 121
S S++ + SN S S + DS E S+S S DS S+ S S S S S
Sbjct: 900 SSDSDSSDS---SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 122 DRESSITNDMGFSDDFS 138
S +N SD S
Sbjct: 957 SNSSDSSNSSDSSDSNS 973
Score = 37.7 bits (86), Expect = 0.078
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +S+ + S S+N S S + +S DS+ DSS
Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + S+ S S D S DS + SDS S+ DS S+ S S S S
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1105 SS-DSSDSSDSSDSSDSS 1121
Score = 37.7 bits (86), Expect = 0.078
Identities = 38/142 (26%), Positives = 57/142 (40%), Gaps = 6/142 (4%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + ++ +SD + S S++ S S + S DS+ DSS +
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS--D 1077
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S SE+ + SN S S DS + SDS DS S+ S S S S S
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS----DSSDSSDSSNSSDSSDSSDSS 1133
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S +N SD +S +
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSD 1155
Score = 37.7 bits (86), Expect = 0.078
Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ ++SD S S++ S S + S DS+ DSS
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S + S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSS--DSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1188 -DSSDSSDSSDSSDSS 1202
Score = 37.4 bits (85), Expect = 0.10
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 5/138 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S++ S S + +S DS+ + S+ +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS--SDSSNSSD 1032
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S++ + S+ S S + DS + SDS S DS S+ S S S S +
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 121 SDRESSITNDMGFSDDFS 138
S +SS ++D S D S
Sbjct: 1093 SS-DSSDSSDSSDSSDSS 1109
Score = 37.0 bits (84), Expect = 0.13
Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 4/141 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S NS + +D + + ++ SSD S + +S DS+ DSS
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD--SNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + SN S S DS SDS S DS + S S +S S +S
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS-SDSSDSSDGSDSD-SSNRSDSSNSSD 866
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD +S E
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNE 887
Score = 37.0 bits (84), Expect = 0.13
Identities = 34/141 (24%), Positives = 55/141 (39%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+ N S +S +D + ++++ SSD S + S +S+ DSS
Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S N + S+ S S + S + S + S DS S+ S S S S S
Sbjct: 997 SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD +S +
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSD 1077
Score = 37.0 bits (84), Expect = 0.13
Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + ++ D+ +SD + S S++ S S + S DS+ +SS
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S +S + + S+ S S D S DS + SDS S DS S+ S S S S S
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSS--DSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1203 -DSSDSSDSSDSSDSS 1217
Score = 37.0 bits (84), Expect = 0.13
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 4/149 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
++ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDS--GSQVPDSLPSTPSPVESTKSFSVH 120
S S + + S+ S S D S DS + SDS S DS S+ S + S S
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Query: 121 SDRESSITNDMGFSDDFSLLESQERCEEE 149
S S +N SD +S +E
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268
Score = 36.6 bits (83), Expect = 0.17
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 3/142 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +SD + S S++ S S + +S DS+ DSS
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN-SSDSSNSSDSSDSSNSSDSSDSS 845
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S + + S+ S+ S DS SDS S DS S+ S S S S SD
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 123 RESSITNDMGFSDDFSLLESQE 144
S +N SD + +S E
Sbjct: 905 SSDS-SNSSDSSDSSNSSDSSE 925
Score = 36.6 bits (83), Expect = 0.17
Identities = 33/135 (24%), Positives = 50/135 (37%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S +S + +D + S S+N S S S DS+ DS
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S+ S+ S DS E S+S S S +S+ S
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 124 ESSITNDMGFSDDFS 138
SS +++ S D S
Sbjct: 919 NSSDSSESSNSSDNS 933
Score = 36.6 bits (83), Expect = 0.17
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 4/141 (2%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S++ NS + ++ + ++++ SSD D DS+ +SS
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S N + S+ S+ S + S DS + S+S DS S+ S S S S S
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSS--DSSDSSNSSDS--DSSDSSNSSDSSDSSNSSDSSE 925
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S+ +++ SD + +S +
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSD 946
Score = 36.6 bits (83), Expect = 0.17
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 5/135 (3%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
N + S +S + +D + S+N S S + S DS+ DSS
Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + +S+ S S + DS + S+S DS S+ S S S S +S
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS----DSSESSNSSDNSNSSDSSNSS- 942
Query: 124 ESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 943 DSSDSSDSSNSSDSS 957
Score = 36.6 bits (83), Expect = 0.17
Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 3/137 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSS-VG 61
++ + + D+ +SD S S++ S S + +S DS+ DSS
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 62 ELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
+ S S++ + SN S S DS + SDS S DS S+ S S S S S
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 122 DRESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1100 S-DSSDSSDSSDSSDSS 1115
Score = 35.8 bits (81), Expect = 0.30
Identities = 34/141 (24%), Positives = 52/141 (36%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+ + S NS + ++ + S++ S S + S DS+ DSS
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + +S+ S S D S S S DS S+ S S S S S
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Query: 124 ESSITNDMGFSDDFSLLESQE 144
S ++ SD ES +
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSD 1086
Score = 35.4 bits (80), Expect = 0.39
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 4/127 (3%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSS--- 59
D+ + + D+ +SD + S S++ S S + S DS+ DSS
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 60 -VGELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFS 118
+ S S++ E S+ S S + DS + SDS DS + S +S +
Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280
Query: 119 VHSDRES 125
SD +S
Sbjct: 1281 NGSDSDS 1287
Score = 34.7 bits (78), Expect = 0.66
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 4/136 (2%)
Query: 3 DNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGE 62
D+ + + D+ +S+ + S S++ S S + S DS+ DSS +
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS--D 1098
Query: 63 LSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSD 122
S S++ + S+ S S + DS + SDS S S S +S++S
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS--DSSESSDSSDS 1156
Query: 123 RESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 1157 SDSSDSSDSSDSSDSS 1172
Score = 34.3 bits (77), Expect = 0.87
Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
Query: 2 KDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVG 61
K + + + D+ +SD + +S ++++ SD + S DS++ DSS
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS----SDSSNS 601
Query: 62 ELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHS 121
S S + + S+ S S S + SDS S+ S ++ +++ S +
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 122 DRESSITNDMGFSDDFS 138
SS ++D S D S
Sbjct: 662 SSNSSDSSDSSDSSDSS 678
Score = 34.3 bits (77), Expect = 0.87
Identities = 29/135 (21%), Positives = 48/135 (35%)
Query: 4 NDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGEL 63
+D + S +S + +D + S +S++ S D DS+ DSS
Sbjct: 550 SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD 609
Query: 64 SFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDR 123
S S + + S + DS SDS +S+ S +
Sbjct: 610 SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669
Query: 124 ESSITNDMGFSDDFS 138
+SS ++D S D S
Sbjct: 670 DSSDSSDSSSSSDSS 684
>gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]
Length = 454
Score = 50.1 bits (118), Expect = 2e-05
Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 13/118 (11%)
Query: 1123 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQ 1182
L G D S ++ ++ G+ + I H TC A + L++GS D T W+ +
Sbjct: 160 LLCTGSDDLSAKLWDVSTGQCVYGIQTH----TCAAVKFDEQKLVTGSFDNTVACWEWSS 215
Query: 1183 QGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
G ++ F+ GHT V SV + ELD+ VSGS D TV + + G + TL
Sbjct: 216 ------GARTQHFR---GHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTL 264
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 49.3 bits (116), Expect = 3e-05
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 9/120 (7%)
Query: 1122 LLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCG-IHLISGSRDTTCMIWQI 1180
L+ + G D I++ + G ++ ++ H D+V L+ G + L+S SRD T IW +
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183
Query: 1181 TQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
+ G K Q+L GH V IS + M S + + +V + +++ +R L
Sbjct: 184 NKHG--------KQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKL 235
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1115 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1174
VVSH + L + D I+ + GK + ++ H+D VTCLA D G L+SGS D +
Sbjct: 650 VVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHDCS 709
Query: 1175 CMIWQI 1180
+W +
Sbjct: 710 LRLWSL 715
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1115 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1174
VVSH + L + D I+ + GK + ++ H+D VTCLA D G L+SGS D +
Sbjct: 643 VVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHDCS 702
Query: 1175 CMIWQI 1180
+W +
Sbjct: 703 LRLWSL 708
>gi|157266266 WD repeat domain 86 [Homo sapiens]
Length = 376
Score = 48.9 bits (115), Expect = 3e-05
Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 35/179 (19%)
Query: 1109 ITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDY------- 1161
I +++ V ++ LFS+ Y D + +V S+ KG++ H + V LA
Sbjct: 99 IVNRILVANNQ---LFSSSY-DRTARVWSVDKGQMSREFRGHRNCVLTLAYSAPWDLPST 154
Query: 1162 -------CGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTEL 1214
G L++GS D T +WQ+ + Q L GHT VL + + T
Sbjct: 155 PCAEEAAAGGLLVTGSTDGTAKVWQVA---------SGCCHQTLRGHTGAVLCLVLDTPG 205
Query: 1215 DMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKT 1273
A +GS D T+ I G+ +R R S + L + N +VYS + ++T
Sbjct: 206 HTAFTGSTDATIRAWDILSGEQLRVFREHRGSVICLELVNR--------LVYSGSADRT 256
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 48.5 bits (114), Expect = 4e-05
Identities = 43/162 (26%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 1116 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1175
V +D + + S Y D ++V + + H + V L D GIH++SGS DT+
Sbjct: 389 VQYDGRRVVSGAY-DFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSI 445
Query: 1176 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1235
+W + + L GH + L+ G+ + ++ VSG+ D TV I I+ GQ
Sbjct: 446 RVWDVETGNCI---------HTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQ 494
Query: 1236 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD 1277
++TL+ P + +T + + + V+ SS + L D
Sbjct: 495 CLQTLQGPNKHQSAVT----CLQFNKNFVITSSDDGTVKLWD 532
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/273 (21%), Positives = 110/273 (40%), Gaps = 46/273 (16%)
Query: 1126 AGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGG 1185
+G DN+++V S GK + ++ H V ++ +ISGS D T +W
Sbjct: 278 SGSDDNTLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAE---- 331
Query: 1186 VPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCE 1245
+ LYGHT+ V + + + VSGSRD T+ + I+ GQ + L
Sbjct: 332 -----TGECIHTLYGHTSTVRCMHLHEK--RVVSGSRDATLRVWDIETGQCLHVLMGHVA 384
Query: 1246 SSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDIC 1304
+ + ++G VV + + + D + L ++ G +V +
Sbjct: 385 AV-------RCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGH-------TNRVYSLQ 430
Query: 1305 IIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVV 1364
G H+V+GS+ + + D+ + N C+ + + G+E I+V
Sbjct: 431 FDGIHVVSGSLDTSIRVWDVETGN-------------CIHTLTGHQSLTSGMELKDNILV 477
Query: 1365 -----GVGKPAEMRSGQLSRKFWGSSKRLSQIS 1392
K ++++GQ + G +K S ++
Sbjct: 478 SGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 510
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 13/88 (14%)
Query: 1153 IVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGIST 1212
++TCL +CG ++SGS D T +W + K + L GHT V S +
Sbjct: 265 VITCL--QFCGNRIVSGSDDNTLKVWS---------AVTGKCLRTLVGHTGGVWSSQMRD 313
Query: 1213 ELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
++ +SGS D T+ + + G+ + TL
Sbjct: 314 --NIIISGSTDRTLKVWNAETGECIHTL 339
Score = 35.4 bits (80), Expect = 0.39
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 1110 TSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISG 1169
T++++ + D + S G D SI+V + G I + H + + + + L+SG
Sbjct: 423 TNRVYSLQFDGIHVVS-GSLDTSIRVWDVETGNCIHTLTGHQSLTSGM--ELKDNILVSG 479
Query: 1170 SRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG-ISTELDMAVSGSRDGTVII 1228
+ D+T IW I + Q L G +V + + ++ S DGTV +
Sbjct: 480 NADSTVKIWDIK---------TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKL 530
Query: 1229 HTIQKGQYMRTL 1240
++ G+++R L
Sbjct: 531 WDLKTGEFIRNL 542
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 48.5 bits (114), Expect = 4e-05
Identities = 43/162 (26%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 1116 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1175
V +D + + S Y D ++V + + H + V L D GIH++SGS DT+
Sbjct: 507 VQYDGRRVVSGAY-DFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSI 563
Query: 1176 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1235
+W + + L GH + L+ G+ + ++ VSG+ D TV I I+ GQ
Sbjct: 564 RVWDVETGNCI---------HTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQ 612
Query: 1236 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD 1277
++TL+ P + +T + + + V+ SS + L D
Sbjct: 613 CLQTLQGPNKHQSAVT----CLQFNKNFVITSSDDGTVKLWD 650
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/273 (21%), Positives = 110/273 (40%), Gaps = 46/273 (16%)
Query: 1126 AGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGG 1185
+G DN+++V S GK + ++ H V ++ +ISGS D T +W
Sbjct: 396 SGSDDNTLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAE---- 449
Query: 1186 VPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCE 1245
+ LYGHT+ V + + + VSGSRD T+ + I+ GQ + L
Sbjct: 450 -----TGECIHTLYGHTSTVRCMHLHEK--RVVSGSRDATLRVWDIETGQCLHVLMGHVA 502
Query: 1246 SSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDIC 1304
+ + ++G VV + + + D + L ++ G +V +
Sbjct: 503 AV-------RCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGH-------TNRVYSLQ 548
Query: 1305 IIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVV 1364
G H+V+GS+ + + D+ + N C+ + + G+E I+V
Sbjct: 549 FDGIHVVSGSLDTSIRVWDVETGN-------------CIHTLTGHQSLTSGMELKDNILV 595
Query: 1365 -----GVGKPAEMRSGQLSRKFWGSSKRLSQIS 1392
K ++++GQ + G +K S ++
Sbjct: 596 SGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 628
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 13/88 (14%)
Query: 1153 IVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGIST 1212
++TCL +CG ++SGS D T +W + K + L GHT V S +
Sbjct: 383 VITCL--QFCGNRIVSGSDDNTLKVWS---------AVTGKCLRTLVGHTGGVWSSQMRD 431
Query: 1213 ELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
++ +SGS D T+ + + G+ + TL
Sbjct: 432 --NIIISGSTDRTLKVWNAETGECIHTL 457
Score = 35.4 bits (80), Expect = 0.39
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 1110 TSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISG 1169
T++++ + D + S G D SI+V + G I + H + + + + L+SG
Sbjct: 541 TNRVYSLQFDGIHVVS-GSLDTSIRVWDVETGNCIHTLTGHQSLTSGM--ELKDNILVSG 597
Query: 1170 SRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG-ISTELDMAVSGSRDGTVII 1228
+ D+T IW I + Q L G +V + + ++ S DGTV +
Sbjct: 598 NADSTVKIWDIK---------TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKL 648
Query: 1229 HTIQKGQYMRTL 1240
++ G+++R L
Sbjct: 649 WDLKTGEFIRNL 660
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 48.5 bits (114), Expect = 4e-05
Identities = 43/162 (26%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 1116 VSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTC 1175
V +D + + S Y D ++V + + H + V L D GIH++SGS DT+
Sbjct: 427 VQYDGRRVVSGAY-DFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSI 483
Query: 1176 MIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQ 1235
+W + + L GH + L+ G+ + ++ VSG+ D TV I I+ GQ
Sbjct: 484 RVWDVETGNCI---------HTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQ 532
Query: 1236 YMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD 1277
++TL+ P + +T + + + V+ SS + L D
Sbjct: 533 CLQTLQGPNKHQSAVT----CLQFNKNFVITSSDDGTVKLWD 570
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/273 (21%), Positives = 110/273 (40%), Gaps = 46/273 (16%)
Query: 1126 AGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGG 1185
+G DN+++V S GK + ++ H V ++ +ISGS D T +W
Sbjct: 316 SGSDDNTLKVWSAVTGKCLRTLVGHTGGVW--SSQMRDNIIISGSTDRTLKVWNAE---- 369
Query: 1186 VPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCE 1245
+ LYGHT+ V + + + VSGSRD T+ + I+ GQ + L
Sbjct: 370 -----TGECIHTLYGHTSTVRCMHLHEK--RVVSGSRDATLRVWDIETGQCLHVLMGHVA 422
Query: 1246 SSLFLTIPNLAISWEGHIVVYSSTEEKTTLKD-KNALHLFSINGKYLGSQILKEQVSDIC 1304
+ + ++G VV + + + D + L ++ G +V +
Sbjct: 423 AV-------RCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGH-------TNRVYSLQ 468
Query: 1305 IIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVV 1364
G H+V+GS+ + + D+ + N C+ + + G+E I+V
Sbjct: 469 FDGIHVVSGSLDTSIRVWDVETGN-------------CIHTLTGHQSLTSGMELKDNILV 515
Query: 1365 -----GVGKPAEMRSGQLSRKFWGSSKRLSQIS 1392
K ++++GQ + G +K S ++
Sbjct: 516 SGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 548
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 13/88 (14%)
Query: 1153 IVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGIST 1212
++TCL +CG ++SGS D T +W + K + L GHT V S +
Sbjct: 303 VITCL--QFCGNRIVSGSDDNTLKVWS---------AVTGKCLRTLVGHTGGVWSSQMRD 351
Query: 1213 ELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
++ +SGS D T+ + + G+ + TL
Sbjct: 352 --NIIISGSTDRTLKVWNAETGECIHTL 377
Score = 35.4 bits (80), Expect = 0.39
Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 1110 TSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISG 1169
T++++ + D + S G D SI+V + G I + H + + + + L+SG
Sbjct: 461 TNRVYSLQFDGIHVVS-GSLDTSIRVWDVETGNCIHTLTGHQSLTSGM--ELKDNILVSG 517
Query: 1170 SRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVG-ISTELDMAVSGSRDGTVII 1228
+ D+T IW I + Q L G +V + + ++ S DGTV +
Sbjct: 518 NADSTVKIWDIK---------TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKL 568
Query: 1229 HTIQKGQYMRTL 1240
++ G+++R L
Sbjct: 569 WDLKTGEFIRNL 580
>gi|142976686 nuclear autoantigen isoform 1 [Homo sapiens]
Length = 797
Score = 47.8 bits (112), Expect = 8e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1115 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1174
VVSH + + D I+ GK+I ++ H+D VT LA D GI+L+SGS D +
Sbjct: 687 VVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCS 746
Query: 1175 CMIWQI 1180
+W +
Sbjct: 747 IRLWNL 752
Score = 33.1 bits (74), Expect = 1.9
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
Query: 1150 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPV----GLASKPFQILYGHTNEV 1205
H D V LA L++ S D T +W + Q VP L +P H V
Sbjct: 479 HFDGVRALAFHPVEPVLVTASEDHTLKLWNL--QKTVPAKKSASLDVEPIYTFRAHIGPV 536
Query: 1206 LSVGISTELDMAVSGSRDGTV 1226
LS+ IS+ + SG D T+
Sbjct: 537 LSLAISSNGEQCFSGGIDATI 557
>gi|142976675 nuclear autoantigen isoform 2 [Homo sapiens]
Length = 713
Score = 47.8 bits (112), Expect = 8e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Query: 1115 VVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTT 1174
VVSH + + D I+ GK+I ++ H+D VT LA D GI+L+SGS D +
Sbjct: 603 VVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCS 662
Query: 1175 CMIWQI 1180
+W +
Sbjct: 663 IRLWNL 668
Score = 33.1 bits (74), Expect = 1.9
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
Query: 1150 HMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPV----GLASKPFQILYGHTNEV 1205
H D V LA L++ S D T +W + Q VP L +P H V
Sbjct: 395 HFDGVRALAFHPVEPVLVTASEDHTLKLWNL--QKTVPAKKSASLDVEPIYTFRAHIGPV 452
Query: 1206 LSVGISTELDMAVSGSRDGTV 1226
LS+ IS+ + SG D T+
Sbjct: 453 LSLAISSNGEQCFSGGIDATI 473
>gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [Homo
sapiens]
Length = 514
Score = 47.4 bits (111), Expect = 1e-04
Identities = 42/156 (26%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 1085 IKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKII 1144
IK + + K + S+ G + T + +VS + LFS G D ++ L K+I
Sbjct: 228 IKIWDLASGKLKLSLTGHIS-----TVRGVIVSTRSPYLFSCGE-DKQVKCWDLEYNKVI 281
Query: 1145 SHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNE 1204
H H+ V L L++ SRD+T IW + + V L GHTN
Sbjct: 282 RHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASV---------HTLSGHTNA 332
Query: 1205 VLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
V +V ++GS D T+ + + G+ TL
Sbjct: 333 VATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL 368
Score = 36.2 bits (82), Expect = 0.23
Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 9/117 (7%)
Query: 1124 FSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQ 1183
F G D +I++ L GK+ + H+ V + +L S D W +
Sbjct: 219 FVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEY- 277
Query: 1184 GGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTL 1240
+K + +GH + V + + +D+ V+ SRD T I ++ + TL
Sbjct: 278 --------NKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTL 326
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 46.6 bits (109), Expect = 2e-04
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 1121 KLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCG-IHLISGSRDTTCMIWQ 1179
+LL + G + I++ + GK++ +++ H ++V L G + L+S SRD T +W
Sbjct: 140 QLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWD 199
Query: 1180 ITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRT 1239
+ G + ++L GH N V S S + M S V + + K +R
Sbjct: 200 LKDDGNM--------MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRK 251
Query: 1240 L 1240
L
Sbjct: 252 L 252
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 46.2 bits (108), Expect = 2e-04
Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 30/178 (16%)
Query: 1130 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVG 1189
D I++ GK I H ++ +A L+S S D T IW ++
Sbjct: 66 DKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVS-------- 117
Query: 1190 LASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLF 1249
+ K + L GH+N V + + ++ VSGS D +V I ++ G+ ++TL P S
Sbjct: 118 -SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL--PAHSD-- 172
Query: 1250 LTIPNLAISWEGHIVVYSSTEE-------------KTTLKDKN---ALHLFSINGKYL 1291
+ + + +G ++V SS + KT + D N + FS NGKY+
Sbjct: 173 -PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229
Score = 34.3 bits (77), Expect = 0.87
Identities = 16/56 (28%), Positives = 29/56 (51%)
Query: 1123 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIW 1178
L +G +D S+++ + GK + + H D V+ + + G ++S S D C IW
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 12/81 (14%)
Query: 1130 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYC---GIHLISGSRDTTCMIWQITQQGGV 1186
DN++++ +KGK + H + C+ ++ G ++SGS D IW + + V
Sbjct: 235 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV 294
Query: 1187 PVGLASKPFQILYGHTNEVLS 1207
Q L GHT+ V+S
Sbjct: 295 ---------QKLQGHTDVVIS 306
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 46.2 bits (108), Expect = 2e-04
Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 30/178 (16%)
Query: 1130 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVG 1189
D I++ GK I H ++ +A L+S S D T IW ++
Sbjct: 66 DKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVS-------- 117
Query: 1190 LASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLF 1249
+ K + L GH+N V + + ++ VSGS D +V I ++ G+ ++TL P S
Sbjct: 118 -SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL--PAHSD-- 172
Query: 1250 LTIPNLAISWEGHIVVYSSTEE-------------KTTLKDKN---ALHLFSINGKYL 1291
+ + + +G ++V SS + KT + D N + FS NGKY+
Sbjct: 173 -PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229
Score = 34.3 bits (77), Expect = 0.87
Identities = 16/56 (28%), Positives = 29/56 (51%)
Query: 1123 LFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIW 1178
L +G +D S+++ + GK + + H D V+ + + G ++S S D C IW
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 12/81 (14%)
Query: 1130 DNSIQVMSLTKGKIISHIIRHMDIVTCLATDYC---GIHLISGSRDTTCMIWQITQQGGV 1186
DN++++ +KGK + H + C+ ++ G ++SGS D IW + + V
Sbjct: 235 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV 294
Query: 1187 PVGLASKPFQILYGHTNEVLS 1207
Q L GHT+ V+S
Sbjct: 295 ---------QKLQGHTDVVIS 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,498,594
Number of Sequences: 37866
Number of extensions: 2369706
Number of successful extensions: 7902
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 7146
Number of HSP's gapped (non-prelim): 651
length of query: 1404
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1289
effective length of database: 13,892,928
effective search space: 17907984192
effective search space used: 17907984192
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.