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Search of human proteins with 149944536
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149944536 ichthyin protein [Homo sapiens]
(466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149944536 ichthyin protein [Homo sapiens] 924 0.0
gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 is... 415 e-116
gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 is... 415 e-116
gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 is... 415 e-116
gi|46409302 NIPA-like domain containing 1 [Homo sapiens] 407 e-113
gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 is... 379 e-105
gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1 is... 249 5e-66
gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1 i... 209 3e-54
gi|13376097 NIPA-like domain containing 2 [Homo sapiens] 150 3e-36
gi|10092687 NIPA-like domain containing 3 [Homo sapiens] 125 1e-28
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 37 0.038
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 36 0.085
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 35 0.11
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 35 0.15
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 35 0.15
gi|169164483 PREDICTED: hypothetical protein [Homo sapiens] 34 0.32
gi|169210552 PREDICTED: hypothetical protein [Homo sapiens] 34 0.32
gi|113414226 PREDICTED: hypothetical protein [Homo sapiens] 34 0.32
gi|113413437 PREDICTED: hypothetical protein [Homo sapiens] 34 0.32
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 34 0.32
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 33 0.55
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 33 0.55
gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens] 32 0.94
gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens] 32 0.94
gi|239749916 PREDICTED: hypothetical protein XP_002347212 [Homo ... 32 1.2
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 32 1.2
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 32 1.2
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 32 1.2
gi|13994190 frizzled 8 [Homo sapiens] 32 1.6
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 31 2.1
>gi|149944536 ichthyin protein [Homo sapiens]
Length = 466
Score = 924 bits (2387), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MPGDSSPGTLPLWDASLSPPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAP 60
MPGDSSPGTLPLWDASLSPPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAP
Sbjct: 1 MPGDSSPGTLPLWDASLSPPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAP 60
Query: 61 GPMELRVSNTSCENGSLLHLYCSSQEVLCQIVNDLSPEVPSNATFHSWQERIRQNYGFYI 120
GPMELRVSNTSCENGSLLHLYCSSQEVLCQIVNDLSPEVPSNATFHSWQERIRQNYGFYI
Sbjct: 61 GPMELRVSNTSCENGSLLHLYCSSQEVLCQIVNDLSPEVPSNATFHSWQERIRQNYGFYI 120
Query: 121 GLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVA 180
GLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVA
Sbjct: 121 GLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVA 180
Query: 181 NFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPE 240
NFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPE
Sbjct: 181 NFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPE 240
Query: 241 EEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFS 300
EEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFS
Sbjct: 241 EEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFS 300
Query: 301 VAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIY 360
VAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIY
Sbjct: 301 VAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIY 360
Query: 361 YVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCASLPHM 420
YVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCASLPHM
Sbjct: 361 YVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCASLPHM 420
Query: 421 HKNPPPSPAPEPTVIRLEDKNVLVDNIELASTSSPEEKPKVFIIHS 466
HKNPPPSPAPEPTVIRLEDKNVLVDNIELASTSSPEEKPKVFIIHS
Sbjct: 421 HKNPPPSPAPEPTVIRLEDKNVLVDNIELASTSSPEEKPKVFIIHS 466
>gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2
isoform a [Homo sapiens]
Length = 360
Score = 415 bits (1066), Expect = e-116
Identities = 207/306 (67%), Positives = 244/306 (79%)
Query: 113 RQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFL 172
R Y FYIGLGLA SS IG S ILKKKGLLRL G+ RA GG YLK+ +WWAG L
Sbjct: 5 RGKYDFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLL 64
Query: 173 TMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGST 232
+M AGEVANF AYAFAPAT+VTPLGALSVL+SAILSSYFL E LNL GK+GC++ + GST
Sbjct: 65 SMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGST 124
Query: 233 VMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIII 292
VMVIHAP+EE++ T+ EM+ K+ D GF+VFA L+++ LILIFV+ PR+GQ NIL+YI I
Sbjct: 125 VMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITI 184
Query: 293 CSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFN 352
CSVIGAFSV+ VKGLGI IK F G PV+RHPL +IL L L + +STQ+N+LNRALDIFN
Sbjct: 185 CSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFN 244
Query: 353 TSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDI 412
TS+V PIYYVFFTT V+T S ILFKEW M D+ GTLSGF TII+G+F+LHAFKD+
Sbjct: 245 TSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSF 304
Query: 413 SCASLP 418
S ASLP
Sbjct: 305 SLASLP 310
>gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2
isoform a [Homo sapiens]
Length = 360
Score = 415 bits (1066), Expect = e-116
Identities = 207/306 (67%), Positives = 244/306 (79%)
Query: 113 RQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFL 172
R Y FYIGLGLA SS IG S ILKKKGLLRL G+ RA GG YLK+ +WWAG L
Sbjct: 5 RGKYDFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLL 64
Query: 173 TMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGST 232
+M AGEVANF AYAFAPAT+VTPLGALSVL+SAILSSYFL E LNL GK+GC++ + GST
Sbjct: 65 SMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGST 124
Query: 233 VMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIII 292
VMVIHAP+EE++ T+ EM+ K+ D GF+VFA L+++ LILIFV+ PR+GQ NIL+YI I
Sbjct: 125 VMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITI 184
Query: 293 CSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFN 352
CSVIGAFSV+ VKGLGI IK F G PV+RHPL +IL L L + +STQ+N+LNRALDIFN
Sbjct: 185 CSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFN 244
Query: 353 TSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDI 412
TS+V PIYYVFFTT V+T S ILFKEW M D+ GTLSGF TII+G+F+LHAFKD+
Sbjct: 245 TSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSF 304
Query: 413 SCASLP 418
S ASLP
Sbjct: 305 SLASLP 310
>gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2
isoform a [Homo sapiens]
Length = 360
Score = 415 bits (1066), Expect = e-116
Identities = 207/306 (67%), Positives = 244/306 (79%)
Query: 113 RQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFL 172
R Y FYIGLGLA SS IG S ILKKKGLLRL G+ RA GG YLK+ +WWAG L
Sbjct: 5 RGKYDFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLL 64
Query: 173 TMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGST 232
+M AGEVANF AYAFAPAT+VTPLGALSVL+SAILSSYFL E LNL GK+GC++ + GST
Sbjct: 65 SMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGST 124
Query: 233 VMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIII 292
VMVIHAP+EE++ T+ EM+ K+ D GF+VFA L+++ LILIFV+ PR+GQ NIL+YI I
Sbjct: 125 VMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITI 184
Query: 293 CSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFN 352
CSVIGAFSV+ VKGLGI IK F G PV+RHPL +IL L L + +STQ+N+LNRALDIFN
Sbjct: 185 CSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFN 244
Query: 353 TSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDI 412
TS+V PIYYVFFTT V+T S ILFKEW M D+ GTLSGF TII+G+F+LHAFKD+
Sbjct: 245 TSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSF 304
Query: 413 SCASLP 418
S ASLP
Sbjct: 305 SLASLP 310
>gi|46409302 NIPA-like domain containing 1 [Homo sapiens]
Length = 410
Score = 407 bits (1045), Expect = e-113
Identities = 213/390 (54%), Positives = 278/390 (71%), Gaps = 17/390 (4%)
Query: 72 CENGSLLHLYC-SSQEVLCQIVND----LSPEVPSNATFH----SWQERIRQNYGFYIGL 122
C G +L L C +S + C+I N SP + ++ + S + Y Y+GL
Sbjct: 13 CREGYVLSLVCPNSSQAWCEITNVSQLLASPVLYTDLNYSINNLSISANVENKYSLYVGL 72
Query: 123 GLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVANF 182
LA SS IGSS ILKKKGLL+L + G TRA GG YLK+ +WW G L+M AGE ANF
Sbjct: 73 VLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWLWWVGLLSMGAGEAANF 132
Query: 183 GAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPEEE 242
AYAFAPAT+VTPLGALSVLISAILSSYFL E LN+ GK+GC++ + GSTVMVIHAP+EE
Sbjct: 133 AAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVIHAPQEE 192
Query: 243 KVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVA 302
+VT++ EM K++D GFI FAV++ V L+LI ++AP+ GQ NIL+YI ICS+IGAFSV+
Sbjct: 193 EVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQTNILVYISICSLIGAFSVS 252
Query: 303 AVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYV 362
+VKGLGI IK + PV +HPL ++L +L LS++TQ+N+LN+ALD FNTSLV PIYYV
Sbjct: 253 SVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTFNTSLVTPIYYV 312
Query: 363 FFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCASLPHMHK 422
FFT++VVT S ILF+EWY M+A DI GTLSGF TII+G+F+LHAFK+ DI+ + L K
Sbjct: 313 FFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKNTDITWSELTSTAK 372
Query: 423 NPPPSPAPEPTVIRLEDKN-VLVDNIELAS 451
E + + + N VL++N+E ++
Sbjct: 373 K-------EAVSLNVNENNYVLLENLECSA 395
>gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2
isoform b [Homo sapiens]
Length = 341
Score = 379 bits (973), Expect = e-105
Identities = 197/306 (64%), Positives = 231/306 (75%), Gaps = 19/306 (6%)
Query: 113 RQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFL 172
R Y FYIGLGLA SS IG S ILKKKGLLRL G+ RAV
Sbjct: 5 RGKYDFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAV----------------- 47
Query: 173 TMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGST 232
AGEVANF AYAFAPAT+VTPLGALSVL+SAILSSYFL E LNL GK+GC++ + GST
Sbjct: 48 --GAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGST 105
Query: 233 VMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIII 292
VMVIHAP+EE++ T+ EM+ K+ D GF+VFA L+++ LILIFV+ PR+GQ NIL+YI I
Sbjct: 106 VMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITI 165
Query: 293 CSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFN 352
CSVIGAFSV+ VKGLGI IK F G PV+RHPL +IL L L + +STQ+N+LNRALDIFN
Sbjct: 166 CSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFN 225
Query: 353 TSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDI 412
TS+V PIYYVFFTT V+T S ILFKEW M D+ GTLSGF TII+G+F+LHAFKD+
Sbjct: 226 TSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSF 285
Query: 413 SCASLP 418
S ASLP
Sbjct: 286 SLASLP 291
>gi|41406091 non-imprinted in Prader-Willi/Angelman syndrome 1
isoform 1 [Homo sapiens]
Length = 329
Score = 249 bits (635), Expect = 5e-66
Identities = 122/300 (40%), Positives = 193/300 (64%), Gaps = 10/300 (3%)
Query: 120 IGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEV 179
+GLG+A +SS + GS+ +L+KKG++R G + YL D +WWAG + MA G++
Sbjct: 30 LGLGVAVVSSLVNGSTFVLQKKGIVRAKRRGTS--------YLTDIVWWAGTIAMAVGQI 81
Query: 180 ANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAP 239
NF AY P +VTPLGAL V +IL+SY L+E LN+LGKLGC++ AGS V++IH+P
Sbjct: 82 GNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLIIHSP 141
Query: 240 EEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAF 299
+ E VTT E+ K+ + F+ + ++L+ L+LIF IAP +G NI++YI ICS++G+F
Sbjct: 142 KSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSF 201
Query: 300 SVAAVKGLGITIKNFFQGLPVVRHPLPYILSL--ILALSLSTQVNFLNRALDIFNTSLVF 357
+V + KG+G+ ++ P + L L L +L S+ Q ++N+AL+ F++S+
Sbjct: 202 TVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFG 261
Query: 358 PIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCASL 417
IYYV FTT+V+ +S ILF+EW ++ VD G GF T+ +G+ ++ FK+ + + +
Sbjct: 262 AIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFNFNLGEM 321
>gi|214010179 non-imprinted in Prader-Willi/Angelman syndrome 1
isoform 2 [Homo sapiens]
Length = 254
Score = 209 bits (533), Expect = 3e-54
Identities = 101/246 (41%), Positives = 160/246 (65%), Gaps = 2/246 (0%)
Query: 174 MAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTV 233
MA G++ NF AY P +VTPLGAL V +IL+SY L+E LN+LGKLGC++ AGS V
Sbjct: 1 MAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVV 60
Query: 234 MVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIIC 293
++IH+P+ E VTT E+ K+ + F+ + ++L+ L+LIF IAP +G NI++YI IC
Sbjct: 61 LIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISIC 120
Query: 294 SVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSL--ILALSLSTQVNFLNRALDIF 351
S++G+F+V + KG+G+ ++ P + L L L +L S+ Q ++N+AL+ F
Sbjct: 121 SLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECF 180
Query: 352 NTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLD 411
++S+ IYYV FTT+V+ +S ILF+EW ++ VD G GF T+ +G+ ++ FK+ +
Sbjct: 181 DSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFN 240
Query: 412 ISCASL 417
+ +
Sbjct: 241 FNLGEM 246
>gi|13376097 NIPA-like domain containing 2 [Homo sapiens]
Length = 368
Score = 150 bits (378), Expect = 3e-36
Identities = 89/293 (30%), Positives = 156/293 (53%), Gaps = 9/293 (3%)
Query: 113 RQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFL 172
R+N G+ LA L + +I S+ ++K L+L R Y K +WW G L
Sbjct: 42 RRNQIHLFGVLLAILGNLVISISLNIQKYSHLQLAQQEHPRP------YFKSVLWWGGVL 95
Query: 173 TMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGST 232
MA GE NF AY FAP T++ PLG +SV SAI+S FL+++L LG + AG+
Sbjct: 96 LMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTY 155
Query: 233 VMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVL-LLVSCLILIFVIAPRYGQRNILIYII 291
++V AP + + + + F+++ +L +L+ C++L F R G ++++I +
Sbjct: 156 LLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFY--KRKGMKHMVILLT 213
Query: 292 ICSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIF 351
+ +++ + +V +VK + I + +P+ YI+ +I+ S QV FLN+A ++
Sbjct: 214 LVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLY 273
Query: 352 NTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFML 404
NT+ V P+ ++FFT + + II ++E+ + + L G LGVF++
Sbjct: 274 NTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLV 326
>gi|10092687 NIPA-like domain containing 3 [Homo sapiens]
Length = 406
Score = 125 bits (313), Expect = 1e-28
Identities = 83/326 (25%), Positives = 162/326 (49%), Gaps = 25/326 (7%)
Query: 88 LCQIVNDLSPEVPSNATFHSWQERIRQNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLV 147
L Q+ S S A+F S++E + IG LA ++ ++ L+K +RL
Sbjct: 11 LQQLPPTSSSSAVSEASF-SYKENL-------IGALLAIFGHLVVSIALNLQKYCHIRLA 62
Query: 148 ATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVANFGAYAFAPATVVTPLGALSVLISAIL 207
+ RA Y K WW G M GE+ F +YAFAP +++ PL A+SV+ SAI+
Sbjct: 63 GSKDPRA------YFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAII 116
Query: 208 SSYFLRESLN--------LLGKLGCVICVAGSTVMVIHAPEEEKVTTIMEMASKMKDTGF 259
F++E +L +GC + V G+ ++V AP + T + + F
Sbjct: 117 GIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPF 176
Query: 260 IVFAVL-LLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKNFFQGL 318
+++ ++ +++ CL+L F NI++ +++ +++G+ +V VK + + QG
Sbjct: 177 LLYMLVEIILFCLLLYFY--KEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGN 234
Query: 319 PVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKE 378
+ +P+ Y++ + + + Q FL++A ++++SL+ + Y+ TT+ +T+ I + +
Sbjct: 235 LQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLD 294
Query: 379 WYSMSAVDIAGTLSGFVTIILGVFML 404
+ + I G + LGVF++
Sbjct: 295 FIGEDVLHICMFALGCLIAFLGVFLI 320
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 37.0 bits (84), Expect = 0.038
Identities = 44/191 (23%), Positives = 88/191 (46%), Gaps = 12/191 (6%)
Query: 116 YGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDA----MWWAGF 171
Y F++ + L FLSSF +++ + G R ++ + G + A + A
Sbjct: 308 YTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIGASR 367
Query: 172 LTMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGS 231
+ A FG APA VV+ G +A+L S+ L + + L GKL + V
Sbjct: 368 ILHALARDDLFGVI-LAPAKVVSRGGNPW---AAVLYSWGLVQLVLLAGKLNTLAAVVTV 423
Query: 232 TVMVIHAPEEEKVTTIMEMASKMKDTGFIVFA----VLLLVSCLILIFVIAPRYGQRNIL 287
+V +A + ++ ++ F +F+ +L + SCL+++F+I+P ++L
Sbjct: 424 FYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLL 483
Query: 288 IYIIICSVIGA 298
+ ++ +++ A
Sbjct: 484 LMGLLAALLTA 494
Score = 29.3 bits (64), Expect = 8.0
Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 326 PYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTS------SIILFKEW 379
P +L I A +LS ++ L A I + ++ V V S + +L+ W
Sbjct: 344 PLVLIGIYATALSASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS-W 402
Query: 380 YSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCASL 417
+ V +AG L+ ++ VF L A+ +D+SC SL
Sbjct: 403 GLVQLVLLAGKLNTLAAVVT-VFYLVAYAAVDLSCLSL 439
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 35.8 bits (81), Expect = 0.085
Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 5 SSPGTLPLWDASLSPPL-GPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVG---SCAP 60
S PG+ PL +L PPL GP R + P+PE G PG + P G S P
Sbjct: 316 SGPGSTPL--GALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGP 373
Query: 61 GPMELRVSNTSCENGSLLH 79
P +S TS +G L H
Sbjct: 374 SP-PFPMSGTSGYSGPLSH 391
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 35.4 bits (80), Expect = 0.11
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 9/60 (15%)
Query: 403 MLHAFKDLDISCASLPHMHKNPPPSPAPEPTVIRLEDKNVLVDNIELASTSSPEEKPKVF 462
++H + D S +P P SP P PT + LE K +TSS +EK K F
Sbjct: 2169 VVHVIRSYDPSAGDVPQTQPEEPVSPKPSPTFMELEPK---------PTTSSIKEKVKAF 2219
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 35.0 bits (79), Expect = 0.15
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 143 LLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEV------ANFGAYAFAPATVVTPL 196
L+ + ++G R +DG G+ M A + ++ A V FGA+AF P V L
Sbjct: 28 LVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTL 87
Query: 197 GALSVLISAIL 207
GA V ++ +L
Sbjct: 88 GAAFVYLADLL 98
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 35.0 bits (79), Expect = 0.15
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 143 LLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEV------ANFGAYAFAPATVVTPL 196
L+ + ++G R +DG G+ M A + ++ A V FGA+AF P V L
Sbjct: 28 LVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTL 87
Query: 197 GALSVLISAIL 207
GA V ++ +L
Sbjct: 88 GAAFVYLADLL 98
>gi|169164483 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 33.9 bits (76), Expect = 0.32
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 6/55 (10%)
Query: 18 SPPLGPDPGGFSRASHAGD---KSRPPAPELGSPGAVRPRVGSC-APGPMELRVS 68
+PP P P R+ H+G +RPP+P G+P A+RP + AP P+ L S
Sbjct: 208 TPP--PGPRRPLRSPHSGSGWTPARPPSPPAGAPEALRPPASTTRAPAPLTLSFS 260
>gi|169210552 PREDICTED: hypothetical protein [Homo sapiens]
Length = 220
Score = 33.9 bits (76), Expect = 0.32
Identities = 16/44 (36%), Positives = 22/44 (50%)
Query: 19 PPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAPGP 62
PP+ P+ G AG ++ P + G GA+RP V C P P
Sbjct: 68 PPVDPEKEGALPPVDAGKEAALPPVDPGKEGALRPVVPGCVPSP 111
>gi|113414226 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 33.9 bits (76), Expect = 0.32
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 6/55 (10%)
Query: 18 SPPLGPDPGGFSRASHAGD---KSRPPAPELGSPGAVRPRVGSC-APGPMELRVS 68
+PP P P R+ H+G +RPP+P G+P A+RP + AP P+ L S
Sbjct: 208 TPP--PGPRRPLRSPHSGSGWTPARPPSPPAGAPEALRPPASTTRAPAPLTLSFS 260
>gi|113413437 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 33.9 bits (76), Expect = 0.32
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 6/55 (10%)
Query: 18 SPPLGPDPGGFSRASHAGD---KSRPPAPELGSPGAVRPRVGSC-APGPMELRVS 68
+PP P P R+ H+G +RPP+P G+P A+RP + AP P+ L S
Sbjct: 208 TPP--PGPRRPLRSPHSGSGWTPARPPSPPAGAPEALRPPASTTRAPAPLTLSFS 260
>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit
16A [Homo sapiens]
Length = 528
Score = 33.9 bits (76), Expect = 0.32
Identities = 16/45 (35%), Positives = 21/45 (46%)
Query: 19 PPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAPGPM 63
PP P+P + G + RPP PE +P VRP G P+
Sbjct: 376 PPTSPEPPEDNDDRQTGAELRPPPPEEDNPEVVRPHNGRVGGSPV 420
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 33.1 bits (74), Expect = 0.55
Identities = 51/249 (20%), Positives = 109/249 (43%), Gaps = 40/249 (16%)
Query: 247 IMEMASKMKDTGFIVFAVLLLVSCLILIF---VIAPRYGQRNILIYIII-------CSVI 296
I+ ++ M +TG I+F ++LL ++ ++ ++ + LIY + I
Sbjct: 93 ILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKI 152
Query: 297 GAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLN-RALDIF-NTS 354
GAF ++ +G F ++++ LP ++ + L +T +LN L IF +
Sbjct: 153 GAFVSITMQNIGAMSSYLF----IIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVG 208
Query: 355 LVFPIY------YVFFTT------VVVTSSIILFKEWYSMSAVDI----AGTLSGFVTII 398
++ P+ Y+ +T+ +V S++++K++ + + G LS T+
Sbjct: 209 IILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLP 268
Query: 399 LGVFMLHAFKDLDISCASLPHMHKNPPPSPAPEPTVIRLEDKNVLVDN-IELASTSSPEE 457
+ V ML + + + H+NP + + K L D+ +E + S +
Sbjct: 269 MHVVMLPNNSESSDVNFMMDYTHRNP-------AGLDENQAKGSLHDSGVEYEAHSDDKC 321
Query: 458 KPKVFIIHS 466
+PK F+ +S
Sbjct: 322 EPKYFVFNS 330
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 33.1 bits (74), Expect = 0.55
Identities = 51/249 (20%), Positives = 109/249 (43%), Gaps = 40/249 (16%)
Query: 247 IMEMASKMKDTGFIVFAVLLLVSCLILIF---VIAPRYGQRNILIYIII-------CSVI 296
I+ ++ M +TG I+F ++LL ++ ++ ++ + LIY + I
Sbjct: 93 ILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKI 152
Query: 297 GAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLN-RALDIF-NTS 354
GAF ++ +G F ++++ LP ++ + L +T +LN L IF +
Sbjct: 153 GAFVSITMQNIGAMSSYLF----IIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVG 208
Query: 355 LVFPIY------YVFFTT------VVVTSSIILFKEWYSMSAVDI----AGTLSGFVTII 398
++ P+ Y+ +T+ +V S++++K++ + + G LS T+
Sbjct: 209 IILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLP 268
Query: 399 LGVFMLHAFKDLDISCASLPHMHKNPPPSPAPEPTVIRLEDKNVLVDN-IELASTSSPEE 457
+ V ML + + + H+NP + + K L D+ +E + S +
Sbjct: 269 MHVVMLPNNSESSDVNFMMDYTHRNP-------AGLDENQAKGSLHDSGVEYEAHSDDKC 321
Query: 458 KPKVFIIHS 466
+PK F+ +S
Sbjct: 322 EPKYFVFNS 330
>gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens]
Length = 365
Score = 32.3 bits (72), Expect = 0.94
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 19 PPLGPDPGGFSRASHAGDKS---RPPAPELGSPGAVRP 53
PP G DP G A A + RP AP+ G PG V P
Sbjct: 148 PPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHP 185
>gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens]
Length = 368
Score = 32.3 bits (72), Expect = 0.94
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 19 PPLGPDPGGFSRASHAGDKS---RPPAPELGSPGAVRP 53
PP G DP G A A + RP AP+ G PG V P
Sbjct: 148 PPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHP 185
>gi|239749916 PREDICTED: hypothetical protein XP_002347212 [Homo
sapiens]
Length = 391
Score = 32.0 bits (71), Expect = 1.2
Identities = 40/201 (19%), Positives = 93/201 (46%), Gaps = 31/201 (15%)
Query: 184 AYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPEEEK 243
++ ++V + +L V+I++I + L+ L ++ V S VMVI P
Sbjct: 26 SFVVVTTSLVVVITSLVVVITSIAIAI-----ATLVVVLTSLVVVTTSLVMVITPP---- 76
Query: 244 VTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFS--V 301
+ + G ++ +++++++CL+L+ G + +++ S++ + V
Sbjct: 77 -------FAVITSLGVVITSLVVIITCLVLVIT---ALGVVITSLGVVVTSLVMVITPLV 126
Query: 302 AAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLS----TQVNFLNRALDIFNTSL-- 355
A + LG+ I + + V+ + I SL + ++ S T + + +L + TSL
Sbjct: 127 AVITPLGVVITSL---VVVITSLVMVITSLTVVITSSIVVITPLVMVITSLTVIITSLFV 183
Query: 356 -VFPIYYVFFTTVVVTSSIIL 375
+ P+ V +VV +S+++
Sbjct: 184 VITPLVMVITFLIVVNTSLVV 204
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 32.0 bits (71), Expect = 1.2
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)
Query: 1 MPGDSSPGTLPLWDASLSPPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAP 60
+PG S T WD S+ P G G + G K P P G PG P C P
Sbjct: 728 LPGSDSVST---WDGSVRTPGGRVKEGGLK----GQKGEPGVP--GPPGRAGPPGSPCLP 778
Query: 61 GP 62
GP
Sbjct: 779 GP 780
>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
sapiens]
Length = 1336
Score = 32.0 bits (71), Expect = 1.2
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)
Query: 1 MPGDSSPGTLPLWDASLSPPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAP 60
+PG S T WD S+ P G G + G K P P G PG P C P
Sbjct: 313 LPGSDSVST---WDGSVRTPGGRVKEGGLK----GQKGEPGVP--GPPGRAGPPGSPCLP 363
Query: 61 GP 62
GP
Sbjct: 364 GP 365
>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
sapiens]
Length = 1516
Score = 32.0 bits (71), Expect = 1.2
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)
Query: 1 MPGDSSPGTLPLWDASLSPPLGPDPGGFSRASHAGDKSRPPAPELGSPGAVRPRVGSCAP 60
+PG S T WD S+ P G G + G K P P G PG P C P
Sbjct: 493 LPGSDSVST---WDGSVRTPGGRVKEGGLK----GQKGEPGVP--GPPGRAGPPGSPCLP 543
Query: 61 GP 62
GP
Sbjct: 544 GP 545
>gi|13994190 frizzled 8 [Homo sapiens]
Length = 694
Score = 31.6 bits (70), Expect = 1.6
Identities = 40/140 (28%), Positives = 54/140 (38%), Gaps = 18/140 (12%)
Query: 7 PGTLPLWDASLSPPLGPDPG--GFSRASHAGDKSRPPAPELGSPGAVRPRVGS---CAPG 61
PG P + P G P G R GD + PPA G G RP G C PG
Sbjct: 172 PGEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPG 231
Query: 62 -PMELRVSNTSCENGSLLHLYCSSQEVLCQIVNDLSPEVPSNATFHSWQERIRQNYGFYI 120
+ + S E L + + Q C + P + F S ER F+I
Sbjct: 232 CQCRAPMVSVSSERHPLYNRVKTGQIANCAL--------PCHNPFFSQDERAFT--VFWI 281
Query: 121 GLG--LAFLSSFLIGSSVIL 138
GL L F+S+F S+ ++
Sbjct: 282 GLWSVLCFVSTFATVSTFLI 301
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 31.2 bits (69), Expect = 2.1
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 38 SRPPAPELGSPGAVRPRVGSCAPGPMELRVSNTSCENGSLLHLYCSSQEVLCQIVNDLSP 97
S PP P+L S + P G P ++L NT + LL SQ + Q+V LSP
Sbjct: 425 SPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELL----VSQHTV-QLVGGLSP 479
Query: 98 -EVPSNATFHSWQERI 112
PS+ S E++
Sbjct: 480 LSSPSDTKAESPAEKV 495
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,997,638
Number of Sequences: 37866
Number of extensions: 958272
Number of successful extensions: 4850
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 4754
Number of HSP's gapped (non-prelim): 141
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.