Guide to the Human Genome
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Search of human proteins with 148839311

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens]       1027   0.0  
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]       1020   0.0  
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]       190   2e-48
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]       138   1e-32
gi|110349719 titin isoform N2-A [Homo sapiens]                         62   9e-10
gi|169167066 PREDICTED: hypothetical protein [Homo sapiens]            54   3e-07
gi|113416187 PREDICTED: hypothetical protein [Homo sapiens]            54   3e-07
gi|113415691 PREDICTED: hypothetical protein [Homo sapiens]            54   3e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    54   3e-07
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    53   7e-07
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    53   7e-07
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    53   7e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         52   1e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    51   3e-06
gi|41152235 ubiquitin specific protease 51 [Homo sapiens]              51   3e-06
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       49   1e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       49   1e-05
gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]            48   2e-05
gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo ...    48   2e-05
gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo ...    48   2e-05
gi|41281612 zinc finger protein 828 [Homo sapiens]                     48   2e-05
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         48   2e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    48   2e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   48   2e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   48   2e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   48   2e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    48   2e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    48   2e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    48   2e-05
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       48   2e-05

>gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens]
          Length = 499

 Score = 1027 bits (2656), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDES 60
           MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDES
Sbjct: 1   MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDES 60

Query: 61  PVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPY 120
           PVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPY
Sbjct: 61  PVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPY 120

Query: 121 FEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEK 180
           FEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEK
Sbjct: 121 FEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEK 180

Query: 181 CKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREED 240
           CKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREED
Sbjct: 181 CKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREED 240

Query: 241 RAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE 300
           RAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE
Sbjct: 241 RAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE 300

Query: 301 SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGY 360
           SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGY
Sbjct: 301 SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGY 360

Query: 361 LRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASE 420
           LRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASE
Sbjct: 361 LRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASE 420

Query: 421 SACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSEC 480
           SACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSEC
Sbjct: 421 SACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSEC 480

Query: 481 ITEDGRTVAVGDIVWGHRR 499
           ITEDGRTVAVGDIVWGHRR
Sbjct: 481 ITEDGRTVAVGDIVWGHRR 499


>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
          Length = 590

 Score = 1020 bits (2638), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDES 60
           MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDES
Sbjct: 1   MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDES 60

Query: 61  PVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPY 120
           PVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPY
Sbjct: 61  PVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPY 120

Query: 121 FEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEK 180
           FEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEK
Sbjct: 121 FEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEK 180

Query: 181 CKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREED 240
           CKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREED
Sbjct: 181 CKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREED 240

Query: 241 RAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE 300
           RAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE
Sbjct: 241 RAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE 300

Query: 301 SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGY 360
           SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGY
Sbjct: 301 SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGY 360

Query: 361 LRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASE 420
           LRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASE
Sbjct: 361 LRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASE 420

Query: 421 SACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSEC 480
           SACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSEC
Sbjct: 421 SACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSEC 480

Query: 481 ITEDGRTVAVGDIVWG 496
           ITEDGRTVAVGDIVWG
Sbjct: 481 ITEDGRTVAVGDIVWG 496


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score =  190 bits (483), Expect = 2e-48
 Identities = 145/524 (27%), Positives = 253/524 (48%), Gaps = 56/524 (10%)

Query: 6   GCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDS 65
           G  + V ++ ++  ALVV+   GE+ F+G+L+D +K+ G  G+P    +    +    D 
Sbjct: 159 GSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIP----VTVFPKREYKDK 214

Query: 66  HGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAP 125
               P + +    Q G+     A G  P + + P P P L       +  P P + EGAP
Sbjct: 215 PEAMPLQSNT--FQEGTEVKCEANGAVPDDPS-PVPHPELSLAESLWTSKPPPLFHEGAP 271

Query: 126 FPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTL 185
           +P PL++RDTY   +PQPPPR IKR +R++ R       I++ I+LRPRQVLC+KCK+++
Sbjct: 272 YPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPTS--IMNAIKLRPRQVLCDKCKNSV 329

Query: 186 SPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAE 245
                      A +   R GS    +  K E+ +    +     ++ K + + + +   E
Sbjct: 330 ----------VAEKKEIRKGSSA-TDSSKYEDKKRRNESVTTVNKKLKTDHKVDGKNQNE 378

Query: 246 QVPRSPVIKISYSTPQGKGEVVKIPSRVHGS---LEPFRPQQAPQDDGSQDPEVL----- 297
              R+ V+K+S +    +G VVK+ ++ + S   L   +  Q+   D ++  EVL     
Sbjct: 379 SQKRNAVVKVS-NIAHSRGRVVKVSAQANTSKAQLSTKKVLQSKNMDHAKAREVLKIAKE 437

Query: 298 DRESRDRPSCAPSASIPKLKLTRPV--PAGADLPPPKIRLKPHRLGDSEHEPVYRAELVG 355
             + +   +     +  K+  TR    P+   L PP++RLKP R  + E++   +  L  
Sbjct: 438 KAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSL-PPRVRLKPQRYRNEENDSSLKTGLEK 496

Query: 356 ELNGYLRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSC----------------PQ--G 397
             +G +     + C    + G A   + S  +  +  S                 PQ  G
Sbjct: 497 MRSGKMAPKPQSRCTSTRSAGEAPSENQSPSKGPEEASSEVQDTNEVHVPGDQDEPQTLG 556

Query: 398 PQG-REGLAFLVSCPEGRADCASESACSSDSLDEARSSGSEGTPADTGDLSPG-----HG 451
            +G +  ++  ++  + ++D +S S CS DS D+ +SS SE + +++ D  PG       
Sbjct: 557 KKGSKNNISVYMTLNQKKSDSSSASVCSIDSTDDLKSSNSECSSSESFDFPPGSMHAPST 616

Query: 452 ASAPSVSREARQTVPPLTVRLHTQSVSECITEDGRTVAVGDIVW 495
           +S  S S+E ++    L +++ +++VS+C+T DGRT+ VGDIVW
Sbjct: 617 SSTSSSSKEEKKLSNSLKMKVFSKNVSKCVTPDGRTICVGDIVW 660


>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
          Length = 560

 Score =  138 bits (347), Expect = 1e-32
 Identities = 105/382 (27%), Positives = 181/382 (47%), Gaps = 32/382 (8%)

Query: 6   GCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDS 65
           G  + V ++ ++  ALVV+   GE+ F+G+L+D +K+ G  G+P    +    +    D 
Sbjct: 159 GSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIP----VTVFPKREYKDK 214

Query: 66  HGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAP 125
               P + +    Q G+     A G  P + + P P P L       +  P P + EGAP
Sbjct: 215 PEAMPLQSNT--FQEGTEVKCEANGAVPDDPS-PVPHPELSLAESLWTSKPPPLFHEGAP 271

Query: 126 FPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTL 185
           +P PL++RDTY   +PQPPPR IKR +R++ R       I++ I+LRPRQVLC+KCK+++
Sbjct: 272 YPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPTS--IMNAIKLRPRQVLCDKCKNSV 329

Query: 186 SPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAE 245
                      A +   R GS    +  K E+ +    +     ++ K + + + +   E
Sbjct: 330 ----------VAEKKEIRKGSSA-TDSSKYEDKKRRNESVTTVNKKLKTDHKVDGKNQNE 378

Query: 246 QVPRSPVIKISYSTPQGKGEVVKIPSRVHGS---LEPFRPQQAPQDDGSQDPEVL----- 297
              R+ V+K+S +    +G VVK+ ++ + S   L   +  Q+   D ++  EVL     
Sbjct: 379 SQKRNAVVKVS-NIAHSRGRVVKVSAQANTSKAQLSTKKVLQSKNMDHAKAREVLKIAKE 437

Query: 298 DRESRDRPSCAPSASIPKLKLTRPV--PAGADLPPPKIRLKPHRLGDSEHEPVYRAELVG 355
             + +   +     +  K+  TR    P+   L PP++RLKP R  + E++   +  L  
Sbjct: 438 KAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSL-PPRVRLKPQRYRNEENDSSLKTGLEK 496

Query: 356 ELNGYLRDSSPAPCADGPAGGL 377
             +G +     + C    + GL
Sbjct: 497 MRSGKMAPKPQSRCTSTRSAGL 518


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 85/359 (23%), Positives = 131/359 (36%), Gaps = 73/359 (20%)

Query: 50    PLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPP----PARGVQPPETTRPEPPPPL 105
             P A +P+V +  V +   R PEE      ++    PP    P + V  P   +PE PPP 
Sbjct: 10465 PPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPK 10524

Query: 106   VPPLPAGSLP----PYPPYFEGAPFPHPLWLRDTYKLWVPQ-------------PPPRTI 148
             VP  P   +P    P PP     P   P  + +  K  VP+             PPP   
Sbjct: 10525 VPEAPKEVVPEKKVPVPP--PKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVP 10582

Query: 149   KRTRRRLSRNRDPG------RLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPA----AP 198
             +  +  +   + P        +    +   P++V+ EK K  + PP+    PP      P
Sbjct: 10583 EAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK-KVPVPPPKKPEVPPTKVPEVP 10641

Query: 199   RARRRLGSGPDRELRKPEEP---------------------ENGEPTAAATARRSKRERR 237
             +        P+    KPE P                     E  EP A        ++  
Sbjct: 10642 KVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPV 10701

Query: 238   EEDRAPA--EQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPE 295
              E +APA   + P  P +K+    P+   EVV  P +    + P +P+  P        E
Sbjct: 10702 PEKKAPAVVAKKPELPPVKV----PEVPKEVV--PEKKVPLVVPKKPEAPPAKVPEVPKE 10755

Query: 296   VLDRESRDRPSC--APSASIPKL--------KLTRPVPAGADLPPPKIRLKPHRLGDSE 344
             V+  +    P     P A +P++        K   PVP  A+ PPP++  +P  +   E
Sbjct: 10756 VVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEE 10814



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 73/316 (23%), Positives = 122/316 (38%), Gaps = 37/316 (11%)

Query: 50    PLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQP--PETTRPEPPPPLVP 107
             P A +P+V +  V +     P++ +    ++      P    +P  P   R E PPP V 
Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVY 10804

Query: 108   PLPAGSLP----------PYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSR 157
               P    P          P P   E  P   P  + +  K  +P+     IK+      +
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPK 10864

Query: 158   NRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARR--RLGSGPDREL-RK 214
               +P ++I    +L+PR            PP   P PP      +  +L + P +++  K
Sbjct: 10865 EPEPEKVIEKP-KLKPR------------PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEK 10911

Query: 215   PEEPENGEPTAAATARRSKRERR---EEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPS 271
             P+ PE  E T        K+ R+   E    P E+V    V++      + K E    P 
Sbjct: 10912 PQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE----PK 10967

Query: 272   RVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPP 331
             ++    +P  P+  P     ++ EV     R+R    P+  +P++K   P+PA    P P
Sbjct: 10968 KLEKVKKPAVPEPPPPKP-VEEVEVPTVTKRERKIPEPT-KVPEIKPAIPLPAPEPKPKP 11025

Query: 332   KIRLKPHRLGDSEHEP 347
             +  +K  +    E EP
Sbjct: 11026 EAEVKTIKPPPVEPEP 11041



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 75/341 (21%), Positives = 127/341 (37%), Gaps = 55/341 (16%)

Query: 49    PPLAPLPQVDESPVNDSHGRAP-----EEGDAEVMQLGSSSPPPARGVQPPETTRPEPPP 103
             PP A +P+V + PV +     P     E   A+V ++    P P + V  P   + E PP
Sbjct: 9999  PPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV-PKKPVPEKKVPVPAPKKVEAPP 10057

Query: 104   PLVPPLPAGSLP------PYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSR 157
               VP +P   +P      P P   E  P   P       K   P P P  + +    L  
Sbjct: 10058 AKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVP-------KKREPVPVPVALPQEEEVLFE 10110

Query: 158   NR-DPGRLIL---STIRLRPRQVLCEK----CKSTLSPPEASPGPPAAPRARRRLGSGPD 209
                 P   +L     +     +VL E+     +    PPE    PP            P+
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170

Query: 210   RELRKPEEPENGEPTAAATARRSKRERR----EEDRAPAEQVPRSP--VIKISYSTPQGK 263
              E+    +P+   P      ++   E++    +++ AP  +VP  P  V +     P+ +
Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPK-E 10229

Query: 264   GEVVKIPSRVHGSLEPFRPQQAPQDDGSQD----------PEVLDRESRDRPSCAP---- 309
              EV+ +        EP   ++ P++  S +          PEV+ +   + P+  P    
Sbjct: 10230 EEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVE 10289

Query: 310   ------SASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSE 344
                   S  IP+ K+  PV    + PP K+   P ++ + +
Sbjct: 10290 APPAKVSKKIPEEKVPVPVQK-KEAPPAKVPEVPKKVPEKK 10329



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 70/308 (22%), Positives = 116/308 (37%), Gaps = 49/308 (15%)

Query: 50   PLAP--LPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPE-----TTRPEPP 102
            P AP  +P+V + PV +     P     E     +  P   +GV   E     T R E P
Sbjct: 9338 PAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPP--AKVPEVQKGVVTEEKITIVTQREESP 9395

Query: 103  PPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPG 162
            PP VP +P   +P      E  P P         +  VP PPP+     ++ +   +   
Sbjct: 9396 PPAVPEIPKKKVPE-----ERKPVPRK-------EEEVP-PPPKVPALPKKPVPEEKVAV 9442

Query: 163  RLILSTIRLRPRQVLCEKC----KSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEP 218
             + ++     PR  + +K     K  ++  + S   P      R   S  +      EE 
Sbjct: 9443 PVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE- 9501

Query: 219  ENGEPTAAATARRSKRERREEDRAPAEQVPRSP---VI--KISYSTPQGKGEVVKIPSRV 273
               E  + +  R  +RE  EE      +V   P   V+  K+   + + + E  ++  R 
Sbjct: 9502 ---EGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQ 9558

Query: 274  HGS--LEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPP 331
                 L+P  P +  +   ++ PE            AP   +P+ K+  PVP    +PPP
Sbjct: 9559 EKKIVLKPKIPAKIEEPPPAKVPE------------APKKIVPEKKVPAPVPKKEKVPPP 9606

Query: 332  KIRLKPHR 339
            K+  +P +
Sbjct: 9607 KVPEEPKK 9614



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 59/282 (20%), Positives = 98/282 (34%), Gaps = 36/282 (12%)

Query: 85   PPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPP 144
            PPPA+  + P+   PE   P   P      PP  P     P P         K+  P P 
Sbjct: 9575 PPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPA 9634

Query: 145  PRTIKRTRRRLSRNRDPGRLILST---------IRLRPRQVLCEKCKSTLSPPEASPGPP 195
                K T R +   ++   L+  T         +   P++ + E+    L P      P 
Sbjct: 9635 ----KVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690

Query: 196  AAPRARRRLGSG-------------PDRELRKPEEPENG---EPTAAATARRSKRERREE 239
                 R+R+                P +E+   EE E     E  A +  R  + E  EE
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEE 9750

Query: 240  -DRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLD 298
             D    E+    P  +        + E  +         EP +P   P     ++P  + 
Sbjct: 9751 YDYKEFEEY--EPTEEYDQYEEYEEREYERYEEHEEYITEPEKP--IPVKPVPEEP--VP 9804

Query: 299  RESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRL 340
             + +  P+     ++P+ K+  P+P     PPPK+  +P ++
Sbjct: 9805 TKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKV 9846



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 70/299 (23%), Positives = 108/299 (36%), Gaps = 59/299 (19%)

Query: 97    TRPEPPPPL--VPPLPAGSLPPYPPYF--------EGAPFPHPLWLRDTYKLWVPQPP-- 144
             T PE P P+  VP  P  + P  PP          E  P P P  L+       P PP  
Sbjct: 9787  TEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLK-------PPPPKV 9839

Query: 145   ---PRTIKRTRRRLS---RNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAP 198
                P+ +   + R+S   R ++      + + ++P++V+ E+ K  +   E +P P   P
Sbjct: 9840  PEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEE-KVPVPRKEVAP-PVRVP 9897

Query: 199   RARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERRE----EDRAPA-----EQVPR 249
                + L   P+    + E   + E            E  E    E+  P       +VPR
Sbjct: 9898  EVPKELE--PEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPR 9955

Query: 250   SPVIKISYSTPQGKG---------EVVKIPSRVHGSLEPFR----PQQAPQDDGSQDPEV 296
              PV +     P  K          EV K P      L P +    P + P+      PE 
Sbjct: 9956  KPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEE 10015

Query: 297   LDRESRDRPSCAPSASIPKL--------KLTRPVPAGADLPPPKIRLKPHRLGDSEHEP 347
                    +   AP A +P++        K+  P P   + PP K+   P +L   E +P
Sbjct: 10016 KVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKP 10074



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 55/281 (19%), Positives = 93/281 (33%), Gaps = 43/281 (15%)

Query: 85    PPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQ-- 142
             P P      P   + E PP  VP +P       P        P P  + +  K  VP+  
Sbjct: 9957  PVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEK 10016

Query: 143   ---PPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPR 199
                P P+ ++    ++                 P++ + EK     +P +    P   P 
Sbjct: 10017 VPVPVPKKVEAPPAKVPE--------------VPKKPVPEKKVPVPAPKKVEAPPAKVPE 10062

Query: 200   ARRRLGSGPDR--------ELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSP 251
               ++L     +        E   P+ P+  EP     A   + E   E+    E VP   
Sbjct: 10063 VPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEE----EIVPEEE 10118

Query: 252   VIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQ---APQDDGSQDPEVLDRESRDRPSCA 308
             V+         + EV+     V    E   P++    P+++   + E    E    P   
Sbjct: 10119 VLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVK 10178

Query: 309   PSASIP------KLKLTRP---VPAGADLPPPKIRLKPHRL 340
             P   +P      K K+T     +P   + PP K+   P ++
Sbjct: 10179 PKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKV 10219



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 47/181 (25%), Positives = 67/181 (37%), Gaps = 34/181 (18%)

Query: 187   PPEASPGPPAAPRARRRLGSGPDRELRKPEE------PENGEPTAAATARRSKRERREED 240
             P E  P P   P+ +    +      +KPEE      P+  +P  A      K+      
Sbjct: 9959  PEEKKPVP--VPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKP----- 10011

Query: 241   RAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE 300
               P E+VP  PV K   + P    EV K P  V     P    +  +   ++ PEV    
Sbjct: 10012 -VPEEKVP-VPVPKKVEAPPAKVPEVPKKP--VPEKKVPVPAPKKVEAPPAKVPEV---- 10063

Query: 301   SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLG-----DSEHEPVYRAELVG 355
                     P   IP+ K   PVP   + PPPK+  K   +        E E ++  E+V 
Sbjct: 10064 --------PKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVP 10115

Query: 356   E 356
             E
Sbjct: 10116 E 10116



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 24/140 (17%)

Query: 209   DRELRKPEEPENGEPTAAATARRSKRERREED-RAPAEQVPRSPVIKISYSTPQGKGEVV 267
             + ++R PEEP    PT        K    E+    P  + P +P  K+    P+   EVV
Sbjct: 10479 EEKVRVPEEPRV-PPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKV----PEAPKEVV 10533

Query: 268   KIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGAD 327
               P +      P  P + P+   ++ PEV            P A++P+ K+   +P   +
Sbjct: 10534 --PEKK----VPVPPPKKPEVPPTKVPEV------------PKAAVPEKKVPEAIPPKPE 10575

Query: 328   LPPPKIRLKPHRLGDSEHEP 347
              PPP++   P  +   +  P
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVP 10595



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 40/173 (23%), Positives = 64/173 (36%), Gaps = 42/173 (24%)

Query: 85   PPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPP 144
            P P      P   + EPP P VP +P   +P      E  P P P           P  P
Sbjct: 9295 PAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPE-----EKKPVPVP--------KKEPAAP 9341

Query: 145  PRTIKRTRRRLSRNRDPGRLIL------STIRLRPRQVLCEKCKSTLSPPEASPGPPAAP 198
            P+  +  ++ +   + P  +        + +    + V+ E+  + ++  E SP PPA P
Sbjct: 9342 PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESP-PPAVP 9400

Query: 199  RARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSP 251
                        E+ K + PE  +P            R+EE+  P  +VP  P
Sbjct: 9401 ------------EIPKKKVPEERKPV----------PRKEEEVPPPPKVPALP 9431



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 33/125 (26%), Positives = 44/125 (35%), Gaps = 18/125 (14%)

Query: 178   CEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERR 237
             C+  K  +  P   PGPP  P+   R   G       P     G P           E+R
Sbjct: 15585 CKSDKVVIQDPYRLPGPPGKPKVLART-KGSMLVSWTPPLDNGGSPITGYWL-----EKR 15638

Query: 238   EEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQ------APQDDGS 291
             EE      +V R+P+ K+       KG    +P  + G    FR          P  + S
Sbjct: 15639 EEGSPYWSRVSRAPITKVGL-----KGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPS 15693

Query: 292   QDPEV 296
              DPEV
Sbjct: 15694 -DPEV 15697



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 28/119 (23%), Positives = 47/119 (39%), Gaps = 5/119 (4%)

Query: 215   PEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVH 274
             P+ PE  E         +K   R+E  A   +VP+  V++     P+   E    P++V 
Sbjct: 10440 PKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE---EPRVPPTKVP 10496

Query: 275   GSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKI 333
               L P   +  P+      P         +   AP   +P+ K+  P P   ++PP K+
Sbjct: 10497 EVLPP--KEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKV 10553



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 4/123 (3%)

Query: 37    LDCTKKSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPET 96
             L+  KK  +   PP  P+ +V+   V     + PE      ++     P P    +P   
Sbjct: 10969 LEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAE 11028

Query: 97    TRPEPPPPLVP-PLPAGSLPPYPPYFEGAPFPHPLWLRDTYK---LWVPQPPPRTIKRTR 152
              +   PPP+ P P P  +    P   + A    P       K     VP+  P  I+  R
Sbjct: 11029 VKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAER 11088

Query: 153   RRL 155
             R+L
Sbjct: 11089 RKL 11091


>gi|169167066 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/177 (28%), Positives = 66/177 (37%), Gaps = 28/177 (15%)

Query: 83  SSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQ 142
           S+ PP+     P TT P PPP   PP P    PP PP     P P P  LR    L +P 
Sbjct: 16  SAQPPSSADTVPGTTYPPPPP---PPPPTPRPPPPPP----LPPPGPRLLR-ACSLLLPT 67

Query: 143 PPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPG--------- 193
            P   +   RR  SR+   GR+             C+   S L PP A P          
Sbjct: 68  EPAPDLPPRRRSSSRSLARGRI-----------TQCQVAASPLVPPPAPPHCPRPLLCFL 116

Query: 194 PPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRS 250
           P A P     L + P   +     P  G+ +    A R +R         +E+ PR+
Sbjct: 117 PAAGPAGLPPLRTSPCSGVTFAGRPRLGQESGQGVAARRRRALPRHPPLASERGPRT 173


>gi|113416187 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/177 (28%), Positives = 66/177 (37%), Gaps = 28/177 (15%)

Query: 83  SSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQ 142
           S+ PP+     P TT P PPP   PP P    PP PP     P P P  LR    L +P 
Sbjct: 16  SAQPPSSADTVPGTTYPPPPP---PPPPTPRPPPPPP----LPPPGPRLLR-ACSLLLPT 67

Query: 143 PPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPG--------- 193
            P   +   RR  SR+   GR+             C+   S L PP A P          
Sbjct: 68  EPAPDLPPRRRSSSRSLARGRI-----------TQCQVAASPLVPPPAPPHCPRPLLCFL 116

Query: 194 PPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRS 250
           P A P     L + P   +     P  G+ +    A R +R         +E+ PR+
Sbjct: 117 PAAGPAGLPPLRTSPCSGVTFAGRPRLGQESGQGVAARRRRALPRHPPLASERGPRT 173


>gi|113415691 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/177 (28%), Positives = 66/177 (37%), Gaps = 28/177 (15%)

Query: 83  SSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQ 142
           S+ PP+     P TT P PPP   PP P    PP PP     P P P  LR    L +P 
Sbjct: 16  SAQPPSSADTVPGTTYPPPPP---PPPPTPRPPPPPP----LPPPGPRLLR-ACSLLLPT 67

Query: 143 PPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPG--------- 193
            P   +   RR  SR+   GR+             C+   S L PP A P          
Sbjct: 68  EPAPDLPPRRRSSSRSLARGRI-----------TQCQVAASPLVPPPAPPHCPRPLLCFL 116

Query: 194 PPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRS 250
           P A P     L + P   +     P  G+ +    A R +R         +E+ PR+
Sbjct: 117 PAAGPAGLPPLRTSPCSGVTFAGRPRLGQESGQGVAARRRRALPRHPPLASERGPRT 173


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 102/420 (24%), Positives = 132/420 (31%), Gaps = 74/420 (17%)

Query: 48   LPPL-APLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLV 106
            LPP   P P V   P        P    A  + + SSSP  AR    P+   P  P P  
Sbjct: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI-PASPSPKG 938

Query: 107  PPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLIL 166
             P P  + PP P      P P           W P PP  T        S    P     
Sbjct: 939  APTPPAATPPSPKGGPATPSPK----------WAPTPPAATPP------SPKGGPA---- 978

Query: 167  STIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAA 226
                           K   +PP A+P  P    A       P      P  P+ G P A 
Sbjct: 979  -----------TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK-GSPAAT 1026

Query: 227  ATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAP 286
               + +         +P      +P+ K + +TP        +PS   G   P   + AP
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP-----AATLPSPKGGPATP-SLKGAP 1080

Query: 287  QDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPPK--IRLKPHRLGDSE 344
                +  P          P   P+   PK     P+P  A  P PK  +   PH+     
Sbjct: 1081 TPPAATPPS---------PKGGPATPSPK---GAPMPPAATPPSPKGGLATPPHK----- 1123

Query: 345  HEPVYRAELVGELNGYL-------RDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQG 397
              P   A       G L         ++PA     P GGLA  +    G      + P  
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA--TPPPKGAPTTPAATPPS 1181

Query: 398  PQGREGLAFLVSCPEGRADC-ASESACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPS 456
            P+G  GLA     P+G     A+        L      G+  TPA T   SP  G + PS
Sbjct: 1182 PKG--GLA--TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPS 1236



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 107/455 (23%), Positives = 143/455 (31%), Gaps = 75/455 (16%)

Query: 49   PPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPP 108
            PP A  P     P   S   AP       M   ++ P P  G+  P        P   PP
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAP-------MPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134

Query: 109  LPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILST 168
             P G L   PP  +GAP   P     + K  +  PPP+    T      +   G    S 
Sbjct: 1135 SPKGGLATPPP--KGAP-TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS- 1190

Query: 169  IRLRPRQVLCEKCKSTLSPPE--ASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAA 226
                P+        +  SP    A+P P  AP         P   L  P  P+    T A
Sbjct: 1191 ----PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-SPKGAPTTPA 1245

Query: 227  ATARRSK--RERREEDRAPAEQVPRSPVIKISYSTPQGKG---EVVKIPSRVHGSLEPFR 281
            AT    K          AP       P +K   +TP  KG     V  P    G      
Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305

Query: 282  PQQAPQDDGSQDPEVLDRESRDRPSCAPS---------ASIPKLKLTRP-------VPAG 325
            P+ AP    +  P          P  AP+            P L  T P        P+ 
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365

Query: 326  ADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGGLADLSSGSS 385
             + P P      H+ G +   P  +             + P+P  D  +  +  LS    
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKR----------GPAIPSPKGDPTSPAVIPLSP--- 1412

Query: 386  GEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSS----GSEGTPA 441
                  K  P  P  REG A        + D  +  A +  SL +A ++    G   TP+
Sbjct: 1413 ------KKAPATPVTREGAA-----TPSKGD-LTPPAVTPVSLKKAPATSAPKGGPATPS 1460

Query: 442  DTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQS 476
              GD  P   A  P   +E     PP   ++ T S
Sbjct: 1461 SKGD--PTLPAVTPPSPKE-----PPAPKQVATSS 1488



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 79/300 (26%), Positives = 104/300 (34%), Gaps = 37/300 (12%)

Query: 47   GLPPLAPLPQVDESPVNDSHGR-APEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPL 105
            G P   PLP+   +P   +    +P+ G A     G+ +PP A    P     P  P P 
Sbjct: 1045 GSPAATPLPK--GAPTTPAATLPSPKGGPATPSLKGAPTPPAA--TPPSPKGGPATPSPK 1100

Query: 106  VPPLPAGSLPPYP------PYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNR 159
              P+P  + PP P      P  +GAP   P     + K  +  PPP+    T      + 
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAP-TTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159

Query: 160  DPGRLILSTIRLRPRQVLCEKCKSTLSPPE--ASPGPPAAPRARRRLGSGPDRELRKPEE 217
              G   L+T    P+        +  SP    A+P P  AP         P   L  P  
Sbjct: 1160 KGG---LAT--PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-S 1213

Query: 218  PENGEPTAAATARRSK--RERREEDRAPAEQVPRSPVIKISYSTPQGKG---EVVKIPSR 272
            P+    T AAT    K          AP       P  K   +TP  KG        P  
Sbjct: 1214 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPS 1273

Query: 273  VHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPPK 332
            + G L        P   G+ +P V+   S   P   P+ S PK     P P  A  P PK
Sbjct: 1274 LKGGL------ATPPHKGAPNPAVVTPPS---PKGGPATSPPK---GAPTPPAATPPSPK 1321



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 98/442 (22%), Positives = 134/442 (30%), Gaps = 64/442 (14%)

Query: 50   PLAPLPQVDESPVNDSHGRAPEEGDAEVMQL-GSSSPPPARGVQPPETTRPEPP------ 102
            P A  P     P       AP    A    L G  + PP +G   P    P  P      
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303

Query: 103  -PPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDP 161
             PP   P P  + PP P    G P P             P PP  T             P
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPK----------GAPTPPAVT------------PP 1341

Query: 162  GRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAA-PRARRRLGSGPDRELRKPEEPE- 219
                  T+   P      K   T    +  P PPAA P  +      P    R P  P  
Sbjct: 1342 SPKGTPTL---PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398

Query: 220  NGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVK---IPSRVHGS 276
             G+PT+ A    S +           + P +PV +   +TP  KG++      P  +  +
Sbjct: 1399 KGDPTSPAVIPLSPK-----------KAPATPVTREGAATP-SKGDLTPPAVTPVSLKKA 1446

Query: 277  LEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAP------SASIPKLKLTRPVPAGADLPP 330
                 P+  P    S+    L   +   P   P      ++S PK     P P GA   P
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506

Query: 331  PKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPA---GGLADLSSGSSGE 387
              I   P  +  +   P  R + +      L   +PA  A   A     +   S   +  
Sbjct: 1507 AVIPSSPKEVPAT---PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563

Query: 388  DDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGSEGTPADTGDLS 447
                K  P  P  +E  +     P       S           + S     TP      S
Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623

Query: 448  PGHGASAPSVSREARQTVPPLT 469
            P  G + P  + +   T PP+T
Sbjct: 1624 PEKGPATP--APKGTPTSPPVT 1643



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 72/295 (24%), Positives = 108/295 (36%), Gaps = 36/295 (12%)

Query: 86   PPARGVQPPETTRPEPPPPLVPPLPAG---SLPPY--PPYFEGAPFPHPLWLRDTYKL-- 138
            PPA  V  P+ T   P P   P  P+    S PP   P  ++GAP P  L +        
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609

Query: 139  --WVPQPPPRTIKRTRRRLSRNRDPGR-----LILSTIRLRPRQVLCEKCKSTLSPPEAS 191
                P PP  T     +  +     G      +  S+++  P       CK   + P+AS
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQAS 1669

Query: 192  PGPPA--APRARRRLGSGPDRE----LRKP--EEPENGEPTAAATARRSKRERREEDRAP 243
             G PA   P A + +   P  E    +  P  + P+  + +A +         +   + P
Sbjct: 1670 KGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP 1729

Query: 244  AEQV---PRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE 300
               V   P  PV K S  T +GK +    P    G L P   + +     +   +VL + 
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGK-DASHSPK---GPLAPPESKASTPLTAAAFEKVLPKP 1785

Query: 301  SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLG---DSEHEPVYRAE 352
                 S APS  +       PVP      PPK +  P   G   +S  +P+  A+
Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPT----LPPKQQFLPSSPGLVLESPSKPLAPAD 1836



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 71/303 (23%), Positives = 97/303 (32%), Gaps = 35/303 (11%)

Query: 42   KSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEP 101
            K GL   PP         +P +   G A            ++ P P  G+  P       
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 102  PPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDP 161
             P   PP P G L    P  +GAP   P     + K     PPP+    T    +     
Sbjct: 1220 TPAATPPSPKGGLATPSP--KGAP-TTPAATPPSPKGGPATPPPKGAP-TPPAATPPSLK 1275

Query: 162  GRLILSTIRLRPRQVL----CEKCKSTLSPPEASPGPPAA--PRARRRLGSGPDRELRKP 215
            G L     +  P   +      K     SPP+ +P PPAA  P  +   G+ P +    P
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335

Query: 216  ----EEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPS 271
                     G PT  AT   SK          +++ P  P      +TP  KG     P 
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSK---GGPTTPSSKEGPTPPA-----ATPSHKGGPAMTPP 1387

Query: 272  RVHGSLEPFRPQQAPQDDGS-QDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPP 330
                   P R    P   G    P V+    +  P      + P  +     P+  DL P
Sbjct: 1388 ------SPKRGPAIPSPKGDPTSPAVIPLSPKKAP------ATPVTREGAATPSKGDLTP 1435

Query: 331  PKI 333
            P +
Sbjct: 1436 PAV 1438



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 101/458 (22%), Positives = 143/458 (31%), Gaps = 76/458 (16%)

Query: 48   LPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPE------- 100
            L P+A  P+  E P  DS   A       +  L + SP P      P+T RP        
Sbjct: 760  LAPVASSPK--ECPTEDSGASATASSKGTLTYL-ADSPSPLGVSVSPQTKRPPTKKGSAG 816

Query: 101  PPPPL------VPPLPAGSLP------------------PYPPYFEGAPFPHPLWLRDTY 136
            P  P+      V P+ A  LP                  P PP  +GAP P  +      
Sbjct: 817  PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876

Query: 137  KLWVP---QPPPRTI-----KRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPP 188
             + +P    P P  +     K      +  + P   + S+   + R     K       P
Sbjct: 877  GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936

Query: 189  EASPGPPAAPRARRRLGS-------GPDRELRKPEEPENG--EPTAAATARRSKRERREE 239
            + +P PPAA     + G         P      P  P+ G   P+               
Sbjct: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996

Query: 240  DRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDR 299
               PA   P+      + + P  KG     P     S  P     +P+   +  P     
Sbjct: 997  KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP----- 1051

Query: 300  ESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNG 359
              +  P+  P+A++P  K     P+    P P     P   G         A +      
Sbjct: 1052 LPKGAPT-TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM------ 1104

Query: 360  YLRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADC-A 418
                  PA     P GGLA  +    G      + P  P+G  GLA     P+G     A
Sbjct: 1105 -----PPAATPPSPKGGLA--TPPHKGAPTTPAATPPSPKG--GLA--TPPPKGAPTTPA 1153

Query: 419  SESACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPS 456
            +        L      G+  TPA T   SP  G + PS
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPP-SPKGGLATPS 1190


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 51/312 (16%)

Query: 42  KSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEP 101
           + G +G   L P P    +P        P  G        ++ PPP   ++PP      P
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP 188

Query: 102 PPPLV--------------PPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRT 147
           PPP V               P P   +PP PP    AP P P          VP P P  
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP----------VPAPAPPA 238

Query: 148 IKRTRRRLSRNRDPGRLI--LSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLG 205
                   +R   PG +    S + L  RQ      ++T + P  SP  P        LG
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQ-----AEATRASPPRSPAEPKG----SALG 289

Query: 206 SGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGE 265
             P+  L  P   +   PT   T+    +E +E  R       ++P        P     
Sbjct: 290 PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP-----SRLPLPPSF 344

Query: 266 VVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAG 325
            ++  S+V+       P +AP+ D    P  L   +   P    S S    +   P PA 
Sbjct: 345 HIRPASQVY-------PDRAPEPD---CPGELKATAPASPRLGQSQSQADERAGTPPPA- 393

Query: 326 ADLPPPKIRLKP 337
             LPPP   L P
Sbjct: 394 PPLPPPAPPLPP 405



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 106/454 (23%), Positives = 151/454 (33%), Gaps = 67/454 (14%)

Query: 48  LPP---LAPLPQV--DESPVNDSHGRAPEEGDAEVMQLGSS---------SPPPARGVQP 93
           LPP   + P  QV  D +P  D  G       A   +LG S         +PPPA  + P
Sbjct: 340 LPPSFHIRPASQVYPDRAPEPDCPGELKATAPASP-RLGQSQSQADERAGTPPPAPPLPP 398

Query: 94  PETTRPEPPPPL---VPPLPAGSLPPYPPY-FEGAPFPHPLWLRDTYKLWVPQPPPRTIK 149
           P    P P PPL    PPLP      +PP  F   P       + +     P+P P + +
Sbjct: 399 PAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTP-------KSSSPALKPKPNPPSPE 451

Query: 150 RTRRRLSRN-RDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGP 208
            T      + RDP +  +  +R      LC   +         PGP  AP+++     GP
Sbjct: 452 NTASSAPVDWRDPSQ--MEKLRNELAAYLCGSRREDRFLSH-RPGPTVAPQSKEG-KKGP 507

Query: 209 DRELRKPEE------PENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQG 262
               R PE+      P    P              E + AP+  +P    I     TP  
Sbjct: 508 ----RLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTP-- 561

Query: 263 KGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPV 322
              V +I + +   L     ++A    GS  P+      R    C   A   KL      
Sbjct: 562 --SVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGR---ICENGADDDKLS----K 612

Query: 323 PAGADLPP------PKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGG 376
           P   +LPP      P   L+P  +      P    E        L  ++P     GPA  
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672

Query: 377 LADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGS 436
           L      +SG     K+      G    +   + P   +   +E         E  +S  
Sbjct: 673 L----KATSGPTTPLKA----TSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724

Query: 437 EGTPADT-GDLSPGHGASAPSVSREARQTVPPLT 469
             TP+   G+ SP      P+    +    PP T
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT 758



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 61/232 (26%), Positives = 78/232 (33%), Gaps = 43/232 (18%)

Query: 48   LPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVP 107
            LP   PLP+   SP + S+ R  EE +     +    PPP     P  +  PEPP P + 
Sbjct: 954  LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVI----PPP-----PEFSNDPEPPAPALQ 1004

Query: 108  PLPAGSLPPYPPYFE---------GAP-------FPHPLWLRDTYKLWVPQPPPRTIKRT 151
             L   S PP   Y +         GAP       FP          L       R++ + 
Sbjct: 1005 YLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKK 1064

Query: 152  RRRLSR-NRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARR--RLGSGP 208
            R  +   +R PG     T R             +LS P      P  P  RR    G  P
Sbjct: 1065 RLYVGEPHRGPGLPHGGTGR-------------SLSSPNCFGPQPGGPEMRRVNSAGRAP 1111

Query: 209  DRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTP 260
               L  P     G    AA A+       +   APA    RSP     Y +P
Sbjct: 1112 PGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPA--AGRSPYTTTRYGSP 1161


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 51/312 (16%)

Query: 42  KSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEP 101
           + G +G   L P P    +P        P  G        ++ PPP   ++PP      P
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP 188

Query: 102 PPPLV--------------PPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRT 147
           PPP V               P P   +PP PP    AP P P          VP P P  
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP----------VPAPAPPA 238

Query: 148 IKRTRRRLSRNRDPGRLI--LSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLG 205
                   +R   PG +    S + L  RQ      ++T + P  SP  P        LG
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQ-----AEATRASPPRSPAEPKG----SALG 289

Query: 206 SGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGE 265
             P+  L  P   +   PT   T+    +E +E  R       ++P        P     
Sbjct: 290 PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP-----SRLPLPPSF 344

Query: 266 VVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAG 325
            ++  S+V+       P +AP+ D    P  L   +   P    S S    +   P PA 
Sbjct: 345 HIRPASQVY-------PDRAPEPD---CPGELKATAPASPRLGQSQSQADERAGTPPPA- 393

Query: 326 ADLPPPKIRLKP 337
             LPPP   L P
Sbjct: 394 PPLPPPAPPLPP 405



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 106/454 (23%), Positives = 151/454 (33%), Gaps = 67/454 (14%)

Query: 48  LPP---LAPLPQV--DESPVNDSHGRAPEEGDAEVMQLGSS---------SPPPARGVQP 93
           LPP   + P  QV  D +P  D  G       A   +LG S         +PPPA  + P
Sbjct: 340 LPPSFHIRPASQVYPDRAPEPDCPGELKATAPASP-RLGQSQSQADERAGTPPPAPPLPP 398

Query: 94  PETTRPEPPPPL---VPPLPAGSLPPYPPY-FEGAPFPHPLWLRDTYKLWVPQPPPRTIK 149
           P    P P PPL    PPLP      +PP  F   P       + +     P+P P + +
Sbjct: 399 PAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTP-------KSSSPALKPKPNPPSPE 451

Query: 150 RTRRRLSRN-RDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGP 208
            T      + RDP +  +  +R      LC   +         PGP  AP+++     GP
Sbjct: 452 NTASSAPVDWRDPSQ--MEKLRNELAAYLCGSRREDRFLSH-RPGPTVAPQSKEG-KKGP 507

Query: 209 DRELRKPEE------PENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQG 262
               R PE+      P    P              E + AP+  +P    I     TP  
Sbjct: 508 ----RLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTP-- 561

Query: 263 KGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPV 322
              V +I + +   L     ++A    GS  P+      R    C   A   KL      
Sbjct: 562 --SVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGR---ICENGADDDKLS----K 612

Query: 323 PAGADLPP------PKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGG 376
           P   +LPP      P   L+P  +      P    E        L  ++P     GPA  
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672

Query: 377 LADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGS 436
           L      +SG     K+      G    +   + P   +   +E         E  +S  
Sbjct: 673 L----KATSGPTTPLKA----TSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724

Query: 437 EGTPADT-GDLSPGHGASAPSVSREARQTVPPLT 469
             TP+   G+ SP      P+    +    PP T
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT 758



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 61/232 (26%), Positives = 78/232 (33%), Gaps = 43/232 (18%)

Query: 48   LPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVP 107
            LP   PLP+   SP + S+ R  EE +     +    PPP     P  +  PEPP P + 
Sbjct: 954  LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVI----PPP-----PEFSNDPEPPAPALQ 1004

Query: 108  PLPAGSLPPYPPYFE---------GAP-------FPHPLWLRDTYKLWVPQPPPRTIKRT 151
             L   S PP   Y +         GAP       FP          L       R++ + 
Sbjct: 1005 YLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKK 1064

Query: 152  RRRLSR-NRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARR--RLGSGP 208
            R  +   +R PG     T R             +LS P      P  P  RR    G  P
Sbjct: 1065 RLYVGEPHRGPGLPHGGTGR-------------SLSSPNCFGPQPGGPEMRRVNSAGRAP 1111

Query: 209  DRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTP 260
               L  P     G    AA A+       +   APA    RSP     Y +P
Sbjct: 1112 PGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPA--AGRSPYTTTRYGSP 1161


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 51/312 (16%)

Query: 42  KSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEP 101
           + G +G   L P P    +P        P  G        ++ PPP   ++PP      P
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP 188

Query: 102 PPPLV--------------PPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRT 147
           PPP V               P P   +PP PP    AP P P          VP P P  
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP----------VPAPAPPA 238

Query: 148 IKRTRRRLSRNRDPGRLI--LSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLG 205
                   +R   PG +    S + L  RQ      ++T + P  SP  P        LG
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQ-----AEATRASPPRSPAEPKG----SALG 289

Query: 206 SGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGE 265
             P+  L  P   +   PT   T+    +E +E  R       ++P        P     
Sbjct: 290 PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP-----SRLPLPPSF 344

Query: 266 VVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAG 325
            ++  S+V+       P +AP+ D    P  L   +   P    S S    +   P PA 
Sbjct: 345 HIRPASQVY-------PDRAPEPD---CPGELKATAPASPRLGQSQSQADERAGTPPPA- 393

Query: 326 ADLPPPKIRLKP 337
             LPPP   L P
Sbjct: 394 PPLPPPAPPLPP 405



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 106/454 (23%), Positives = 151/454 (33%), Gaps = 67/454 (14%)

Query: 48  LPP---LAPLPQV--DESPVNDSHGRAPEEGDAEVMQLGSS---------SPPPARGVQP 93
           LPP   + P  QV  D +P  D  G       A   +LG S         +PPPA  + P
Sbjct: 340 LPPSFHIRPASQVYPDRAPEPDCPGELKATAPASP-RLGQSQSQADERAGTPPPAPPLPP 398

Query: 94  PETTRPEPPPPL---VPPLPAGSLPPYPPY-FEGAPFPHPLWLRDTYKLWVPQPPPRTIK 149
           P    P P PPL    PPLP      +PP  F   P       + +     P+P P + +
Sbjct: 399 PAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTP-------KSSSPALKPKPNPPSPE 451

Query: 150 RTRRRLSRN-RDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGP 208
            T      + RDP +  +  +R      LC   +         PGP  AP+++     GP
Sbjct: 452 NTASSAPVDWRDPSQ--MEKLRNELAAYLCGSRREDRFLSH-RPGPTVAPQSKEG-KKGP 507

Query: 209 DRELRKPEE------PENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQG 262
               R PE+      P    P              E + AP+  +P    I     TP  
Sbjct: 508 ----RLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTP-- 561

Query: 263 KGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPV 322
              V +I + +   L     ++A    GS  P+      R    C   A   KL      
Sbjct: 562 --SVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGR---ICENGADDDKLS----K 612

Query: 323 PAGADLPP------PKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGG 376
           P   +LPP      P   L+P  +      P    E        L  ++P     GPA  
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672

Query: 377 LADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGS 436
           L      +SG     K+      G    +   + P   +   +E         E  +S  
Sbjct: 673 L----KATSGPTTPLKA----TSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724

Query: 437 EGTPADT-GDLSPGHGASAPSVSREARQTVPPLT 469
             TP+   G+ SP      P+    +    PP T
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT 758



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 61/232 (26%), Positives = 78/232 (33%), Gaps = 43/232 (18%)

Query: 48   LPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVP 107
            LP   PLP+   SP + S+ R  EE +     +    PPP     P  +  PEPP P + 
Sbjct: 954  LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVI----PPP-----PEFSNDPEPPAPALQ 1004

Query: 108  PLPAGSLPPYPPYFE---------GAP-------FPHPLWLRDTYKLWVPQPPPRTIKRT 151
             L   S PP   Y +         GAP       FP          L       R++ + 
Sbjct: 1005 YLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKK 1064

Query: 152  RRRLSR-NRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARR--RLGSGP 208
            R  +   +R PG     T R             +LS P      P  P  RR    G  P
Sbjct: 1065 RLYVGEPHRGPGLPHGGTGR-------------SLSSPNCFGPQPGGPEMRRVNSAGRAP 1111

Query: 209  DRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTP 260
               L  P     G    AA A+       +   APA    RSP     Y +P
Sbjct: 1112 PGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPA--AGRSPYTTTRYGSP 1161


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 67/289 (23%), Positives = 103/289 (35%), Gaps = 39/289 (13%)

Query: 52  APLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPAR---GVQPPETTRPEPPPPLVPP 108
           +P  +  E+       R+P        +  S +PPP R      PP    P PPP    P
Sbjct: 532 SPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSP 591

Query: 109 LPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRT------RRRLSRNRDPG 162
            P    PP    +  +P P         K     PPP   +R       +RR+S +  P 
Sbjct: 592 SPRRYSPPIQRRYSPSPPP---------KRRTASPPPPPKRRASPSPPPKRRVSHSPPPK 642

Query: 163 RLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGE 222
           +      + R   +  +  K   S P  S     +P+  +R    P    R P+   +  
Sbjct: 643 QRSSPVTKRRSPSLSSKHRKG--SSPSRSTREARSPQPNKR--HSPSPRPRAPQTSSSPP 698

Query: 223 PT-AAATARRSKRERREEDRAPAEQVPRSP----VIKISYSTPQGKGEVVKIPSRVHGSL 277
           P    A++   +R+       P  +V R+P    + K +  +PQ    V    S V GS 
Sbjct: 699 PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRS-VSGSP 757

Query: 278 EPF--RPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPA 324
           EP   +P   P    SQ P           + +P+  + K K   P P+
Sbjct: 758 EPAAKKPPAPPSPVQSQSPST---------NWSPAVPVKKAKSPTPSPS 797



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 84/354 (23%), Positives = 126/354 (35%), Gaps = 43/354 (12%)

Query: 52  APLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPP--L 109
           +P P+   SPV     R+         +  S SP P +  + PE   PEP   +  P   
Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPEL--PEPSVKVKEPSVQ 236

Query: 110 PAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTR-RRLSRNRDPGRLILST 168
            A S        +  P P P            +   +T  R+R R  SR+R   R   S 
Sbjct: 237 EATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR---SP 293

Query: 169 IRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLG----SGPDRELRKPEEPENGEPT 224
              RPR+    + +S    P   P P   P  RRR        P R  R          +
Sbjct: 294 SHTRPRR--RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS 351

Query: 225 AAATARRSKRERREEDRAPAEQVPR---SPVIKISYSTPQGKGEVVKIPSRVHGSLEPFR 281
           +A+ +  S        R+P ++ P+   SP  K    +P         P R H    P  
Sbjct: 352 SASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASP-----PRRRHRPSPPAT 406

Query: 282 PQQAPQDDGSQDPEVLDRESRDRPSCAP---SASIPKLKLTRPVPAGADLPPPKIRLKPH 338
           P   P+   S  P+  +R  + R S +P   S  + K K T       + P P  + +  
Sbjct: 407 P--PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEK----RESPSPAPKPRKV 460

Query: 339 RLGDSEHE---PVYRAELVGELNGYLRDSSPAPCADGPAGGLADLSSGSSGEDD 389
            L +SE +    +  A+ V +   Y R +  +          +D  S SS ED+
Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS---------SDSGSSSSSEDE 505



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 64/256 (25%), Positives = 95/256 (37%), Gaps = 60/256 (23%)

Query: 86  PPARGVQPPETTR---PEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQ 142
           PP R   PP  TR   P   PP     P+    P PP    +P               PQ
Sbjct: 374 PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP-PPKTRHSP--------------TPQ 418

Query: 143 PPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARR 202
              RT +++R  +S  R  G++               K K T    E    P  AP+ R+
Sbjct: 419 QSNRT-RKSRVSVSPGRTSGKV--------------TKHKGT----EKRESPSPAPKPRK 459

Query: 203 RLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQG 262
                   EL + EE + G+  AA + ++ ++ RR+  ++ ++          S S+   
Sbjct: 460 -------VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD----------SGSSSSS 502

Query: 263 KGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTR-P 321
           + E  K  S V       R + +P    S  P    +E+  R     S S P  +  R P
Sbjct: 503 EDERPK-RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP 561

Query: 322 VPAGADLPPPKIRLKP 337
            PA    PPP+ R  P
Sbjct: 562 SPA----PPPRRRRTP 573



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 33/144 (22%), Positives = 50/144 (34%), Gaps = 5/144 (3%)

Query: 191 SPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRS 250
           SP PP   R R    + P R  R P  P      +    RRS   RR          P  
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSP 608

Query: 251 PVIKISYS--TPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCA 308
           P  + + S   P  +      P +   S  P   Q++      + P +    S+ R   +
Sbjct: 609 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL---SSKHRKGSS 665

Query: 309 PSASIPKLKLTRPVPAGADLPPPK 332
           PS S  + +  +P    +  P P+
Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPR 689


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 88/340 (25%), Positives = 120/340 (35%), Gaps = 44/340 (12%)

Query: 59  ESPVNDSHGRAPEE-GDAEVMQLGSSS-----PPPARGVQPPETTRPEPPPPLVPPLPAG 112
           E    D  G   EE   AE M   +       PPP      P    P PPP   PP P  
Sbjct: 370 EEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLC 429

Query: 113 SLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLR 172
             PP P      P P P   ++  +   P   P T  R R         GR  L+  +  
Sbjct: 430 PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKR---------GRPPLTPSQRA 480

Query: 173 PRQVLCEKCKSTLSPPEASP-----GPP-----AAPRARRRLGSGPDRELRKPEEPENGE 222
            R+      + T SPP  +P     GPP      AP++   L     + +R+   P    
Sbjct: 481 EREAARAGPEGT-SPPTPTPSTATGGPPEDSPTVAPKSTTFL-----KNIRQFIMP---- 530

Query: 223 PTAAATARRSKRERR--EEDRAPAEQVPRSPVIKISYST-PQGKGEVVKIPSRVHGSLEP 279
             +A ++R  K  RR  +ED     +V  SPV++   +T P    E   +PS       P
Sbjct: 531 VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP 590

Query: 280 FRPQQAPQDDGSQDPEVLDR---ESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLK 336
             P   P+   S   E   R    +R+ P   P+   P      P PA +   P  +R  
Sbjct: 591 STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLR-A 649

Query: 337 PHRLGDSEHEPVYRAELVGELNG--YLRDSSPAPCADGPA 374
           P       H  +Y + L     G     +  P P  D PA
Sbjct: 650 PQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPA 689



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 86/402 (21%), Positives = 126/402 (31%), Gaps = 80/402 (19%)

Query: 49  PPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPP----- 103
           PP AP P     P+ +       E       L    PPP     PP    P P P     
Sbjct: 583 PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSR 642

Query: 104 -PLV----------------------PPLPAGSLP-PYPPYFEGAPF-PHPLWLRDTYKL 138
            PL+                      PPL A   P P PP  + +P  P P  +  T  L
Sbjct: 643 RPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHL 702

Query: 139 WVPQPPPRTIKRTRRRLSRNRDP----GRLILSTIRLRPRQVL-CEKCKSTLSPPEASPG 193
            +P+  P      +  +S +  P    G    + + L+P Q L  +     L PP+    
Sbjct: 703 SLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL-LQPLQALQTQLLPQALPPPQPQLQ 761

Query: 194 PPAAPR-----ARRRLGSGPDRELRKPEE----------------PENGEPTAAATARRS 232
           PP +P+      + R+       L   EE                 +  +   AA+   S
Sbjct: 762 PPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLS 821

Query: 233 KRERREEDRAPAEQV-PRSPV------IKISYSTPQGKGEVVKIPSRVH---------GS 276
              + EE     +Q+  R PV      ++     P G    V+ P   H         G 
Sbjct: 822 PGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQ 881

Query: 277 LEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIP----KLKLTRPVPAGADLPPPK 332
                P+  P+       +  D  + D  S + + S+P    + K+    P G   P   
Sbjct: 882 ARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGS 941

Query: 333 ---IRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCAD 371
              +   P R   S H    R    G   G LR      C +
Sbjct: 942 GGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVN 983



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 72/274 (26%), Positives = 92/274 (33%), Gaps = 37/274 (13%)

Query: 85   PPPARGVQPPETTRPE---PPP------------PLVPPLPAGSLPP---YPPYFEGAPF 126
            PPP+R   PP  T P+   PPP             L PP PA S PP     P FE    
Sbjct: 1923 PPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEV 1982

Query: 127  PHPLWLRD---TYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKS 183
               L   D      L   +P    I       S +  PG    S     P         +
Sbjct: 1983 VSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGD--SSEEESSPTSRYIHFPVT 2040

Query: 184  TLSPPEASP-GPPAAPRARRRLG--SGPDRELRKPEEPE-NGEPTAAATARRSKRERREE 239
             +S P  +P   P APR  +  G   G D E    ++P   G P +     R+       
Sbjct: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100

Query: 240  DRA-PAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLD 298
            DRA P E +P S ++        G G+         G  E   P   P  +GSQ  + L 
Sbjct: 2101 DRARPPEDLP-SEIVDFVLKNLGGPGD------GGAGPREESLPPAPPLANGSQPSQGLT 2153

Query: 299  RESRDRPSCAPSASIPKLKLTRPVPAGADLPPPK 332
                D       A +P     R +  G    PPK
Sbjct: 2154 ASPAD--PTRTFAWLPGAPGVRVLSLGPAPEPPK 2185



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 69/252 (27%), Positives = 85/252 (33%), Gaps = 67/252 (26%)

Query: 49   PPLA----PLPQVDESPVNDSHGRA--PEEGDAEVMQLGSSSPPPARG------------ 90
            PPLA    P   +  SP + +   A  P      V+ LG +  PP               
Sbjct: 2140 PPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQ 2199

Query: 91   --VQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTI 148
              V+      P PPP   PPLP    P  P  +   P P  L +     +  P PPP   
Sbjct: 2200 VFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGP-LLGVLPVVGVVRPAPPPPP- 2257

Query: 149  KRTRRRLSRNRDPGRLILST-IRLRPRQVLCEKCKSTL---SPPEASPGPPAAPRARR-- 202
                        P  L+LS+     PRQ +  K  ST    SPP  +P P  APR     
Sbjct: 2258 -----------PPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP--APPPYKAPRLDEDG 2304

Query: 203  ----------RLGSGPDRELR-------------KPEEPENGEPTAAATARRSKRERREE 239
                       LGSG    +R             +P EP  GE +      RS      E
Sbjct: 2305 EASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPA-GEESPGPLQERSPLLPLPE 2363

Query: 240  DRAPAEQVPRSP 251
            D  P  QVP  P
Sbjct: 2364 DGPP--QVPDGP 2373



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 5/55 (9%)

Query: 188  PEASPGPPAAPRARRRLGSGPDRE--LRKPEEPENGEPTAAATARRSKRERREED 240
            PEASPGPP     RR  G+G  RE  +  P   E        +ARR  ++R   D
Sbjct: 1036 PEASPGPPG---PRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYD 1087


>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
          Length = 711

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 48/176 (27%), Positives = 69/176 (39%), Gaps = 19/176 (10%)

Query: 205 GSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKG 264
           G+ P+  + K  + E  E  A AT   S+RE  E    P ++   +P   +++S+  G  
Sbjct: 24  GASPEEAVEKAGKME--EAAAGATKASSRREAEEMKLEPLQEREPAPEENLTWSSSGGDE 81

Query: 265 EVV-KIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVP 323
           +V+  IP R H S  P  P++ P+            + R R    P  S P     RP P
Sbjct: 82  KVLPSIPLRCHSSSSPVCPRRKPRP---------RPQPRARSRSQPGLSAPPPPPARPPP 132

Query: 324 AGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGGLAD 379
                PPP  R +  R       P  R +     +G L  S       G  GGL D
Sbjct: 133 PPPPPPPPAPRPRAWRGSRRRSRPGSRPQTRRSCSGDLDGS-------GDPGGLGD 181



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 36/115 (31%), Positives = 46/115 (40%), Gaps = 21/115 (18%)

Query: 69  APEE--------GDAEVM-----QLGSSSPP------PARGVQPPETTRPEPPPPLVPPL 109
           APEE        GD +V+     +  SSS P      P    QP   +R +P     PP 
Sbjct: 67  APEENLTWSSSGGDEKVLPSIPLRCHSSSSPVCPRRKPRPRPQPRARSRSQPGLSAPPPP 126

Query: 110 PAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRL 164
           PA   PP PP     P P P   R + +   P   P+T +     L  + DPG L
Sbjct: 127 PA--RPPPPPPPPPPPAPRPRAWRGSRRRSRPGSRPQTRRSCSGDLDGSGDPGGL 179



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 5/76 (6%)

Query: 180 KCKSTLSP--PEASPGPPAAPRARRRLGSG---PDRELRKPEEPENGEPTAAATARRSKR 234
           +C S+ SP  P   P P   PRAR R   G   P     +P  P    P  A   R  + 
Sbjct: 90  RCHSSSSPVCPRRKPRPRPQPRARSRSQPGLSAPPPPPARPPPPPPPPPPPAPRPRAWRG 149

Query: 235 ERREEDRAPAEQVPRS 250
            RR        Q  RS
Sbjct: 150 SRRRSRPGSRPQTRRS 165


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 127/500 (25%), Positives = 158/500 (31%), Gaps = 95/500 (19%)

Query: 47   GLPPLAPLPQVDESPVNDSHGRAP------EEGDAEVMQLGSSSPPPARGVQPPETTRPE 100
            G P   PLP    SP  +S G         +E  A     G  SPP  R +  PE T  E
Sbjct: 601  GGPEPLPLPPA-RSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNL--PEGT--E 655

Query: 101  PPPPLVPPLPAGSLPPY----PPYFEGAPFPHPL----WLRDTYKLWVPQPPPRTIKRTR 152
             PP L   LP    PPY    P     +P P P     W   +Y    P  PP   +  R
Sbjct: 656  RPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAF-SYLAGPPATPPDPPRPKR 714

Query: 153  RRLSRNRDPGRL-----------------ILSTIRLRP-RQVLCEKCKS-TLSPPEASP- 192
            R  S +R PG                     +T+  RP R  L     S T +P   +P 
Sbjct: 715  RSHSLSR-PGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPR 773

Query: 193  -----------GPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDR 241
                       GPP  P  R    SGP  E    +E    +  A    RR+  E      
Sbjct: 774  SQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSE 833

Query: 242  APAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRES 301
             P    P  P        P  +G                 P +    +G    E  +   
Sbjct: 834  PPGPPAPAGPASDTEEEEPGPEGT---------------PPSRGSSGEGLPFAEEGNLTI 878

Query: 302  RDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYL 361
            + RP   P+   P+     PVP G D    +      R    E EP+  A L        
Sbjct: 879  KQRPK--PAGPPPR---ETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLA------- 926

Query: 362  RDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASES 421
                 A    GPA   A L S + GE     S PQ P+     A  V  P   +      
Sbjct: 927  --FGVASATPGPA---APLPSPTPGESPPASSLPQ-PEPSSLPAQGVPTPLAPSPAMQPP 980

Query: 422  A--CSSDSLDEARSS---GSEGTPADTGDL--SPGHGASAPSVSREARQTV---PPLTVR 471
               C    L+ + +S   G    PA    L   PG G +   VS    Q     P L  R
Sbjct: 981  VPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPR 1040

Query: 472  LHTQSVSECITEDGRTVAVG 491
            L  + V     E   TV  G
Sbjct: 1041 LGPRPVPPPRPESTGTVGPG 1060



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 35/168 (20%), Positives = 55/168 (32%), Gaps = 31/168 (18%)

Query: 85   PPPARGVQPPETTRPEPPPPLVP----PLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWV 140
            P P  G  PP ++ P+P P  +P    P P    P   P     P P             
Sbjct: 941  PSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQP-----PVP------------- 982

Query: 141  PQPPPRTIKRTRRRLSRNRDPGRLILSTIRL-------RPRQVLCEKC--KSTLSPPEAS 191
            P P P        R +   +P     + +++       +P  V C +         P   
Sbjct: 983  PCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLG 1042

Query: 192  PGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREE 239
            P P   PR       GP +  ++ E+  +    A   A +S   + +E
Sbjct: 1043 PRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQE 1090


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 127/500 (25%), Positives = 158/500 (31%), Gaps = 95/500 (19%)

Query: 47   GLPPLAPLPQVDESPVNDSHGRAP------EEGDAEVMQLGSSSPPPARGVQPPETTRPE 100
            G P   PLP    SP  +S G         +E  A     G  SPP  R +  PE T  E
Sbjct: 683  GGPEPLPLPPA-RSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNL--PEGT--E 737

Query: 101  PPPPLVPPLPAGSLPPY----PPYFEGAPFPHPL----WLRDTYKLWVPQPPPRTIKRTR 152
             PP L   LP    PPY    P     +P P P     W   +Y    P  PP   +  R
Sbjct: 738  RPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAF-SYLAGPPATPPDPPRPKR 796

Query: 153  RRLSRNRDPGRL-----------------ILSTIRLRP-RQVLCEKCKS-TLSPPEASP- 192
            R  S +R PG                     +T+  RP R  L     S T +P   +P 
Sbjct: 797  RSHSLSR-PGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPR 855

Query: 193  -----------GPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDR 241
                       GPP  P  R    SGP  E    +E    +  A    RR+  E      
Sbjct: 856  SQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSE 915

Query: 242  APAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRES 301
             P    P  P        P  +G                 P +    +G    E  +   
Sbjct: 916  PPGPPAPAGPASDTEEEEPGPEGT---------------PPSRGSSGEGLPFAEEGNLTI 960

Query: 302  RDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYL 361
            + RP   P+   P+     PVP G D    +      R    E EP+  A L        
Sbjct: 961  KQRPK--PAGPPPR---ETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLA------- 1008

Query: 362  RDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASES 421
                 A    GPA   A L S + GE     S PQ P+     A  V  P   +      
Sbjct: 1009 --FGVASATPGPA---APLPSPTPGESPPASSLPQ-PEPSSLPAQGVPTPLAPSPAMQPP 1062

Query: 422  A--CSSDSLDEARSS---GSEGTPADTGDL--SPGHGASAPSVSREARQTV---PPLTVR 471
               C    L+ + +S   G    PA    L   PG G +   VS    Q     P L  R
Sbjct: 1063 VPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPR 1122

Query: 472  LHTQSVSECITEDGRTVAVG 491
            L  + V     E   TV  G
Sbjct: 1123 LGPRPVPPPRPESTGTVGPG 1142



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 35/168 (20%), Positives = 55/168 (32%), Gaps = 31/168 (18%)

Query: 85   PPPARGVQPPETTRPEPPPPLVP----PLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWV 140
            P P  G  PP ++ P+P P  +P    P P    P   P     P P             
Sbjct: 1023 PSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQP-----PVP------------- 1064

Query: 141  PQPPPRTIKRTRRRLSRNRDPGRLILSTIRL-------RPRQVLCEKC--KSTLSPPEAS 191
            P P P        R +   +P     + +++       +P  V C +         P   
Sbjct: 1065 PCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLG 1124

Query: 192  PGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREE 239
            P P   PR       GP +  ++ E+  +    A   A +S   + +E
Sbjct: 1125 PRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQE 1172


>gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 180

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 53/170 (31%), Positives = 63/170 (37%), Gaps = 11/170 (6%)

Query: 81  GSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWV 140
           GS  PP ARG  P ET  P P    +PPL     PP  P   G P P     R   + W 
Sbjct: 15  GSHFPPAARGRLPGETLSPSPRAAALPPLQ--QRPPGAPGALGRPKPVSRGPRAGLREWP 72

Query: 141 PQP--PPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAP 198
            QP  P       + R      PG     T    P +       +T+S    SPG PA  
Sbjct: 73  QQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGL 132

Query: 199 RARR--RLGSGPDRELRKPEEPENGEPTAAATAR---RSKRERREEDRAP 243
              R  R   G    +  P  P    P  A T R    S+R R+E+ R P
Sbjct: 133 HRSREPRPQDGTPPPVDTP--PRTARPRPAFTPRPVVGSERPRQEQLRGP 180


>gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo
           sapiens]
          Length = 180

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 53/170 (31%), Positives = 63/170 (37%), Gaps = 11/170 (6%)

Query: 81  GSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWV 140
           GS  PP ARG  P ET  P P    +PPL     PP  P   G P P     R   + W 
Sbjct: 15  GSHFPPAARGRLPGETLSPSPRAAALPPLQ--QRPPGAPGALGRPKPVSRGPRAGLREWP 72

Query: 141 PQP--PPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAP 198
            QP  P       + R      PG     T    P +       +T+S    SPG PA  
Sbjct: 73  QQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGL 132

Query: 199 RARR--RLGSGPDRELRKPEEPENGEPTAAATAR---RSKRERREEDRAP 243
              R  R   G    +  P  P    P  A T R    S+R R+E+ R P
Sbjct: 133 HRSREPRPQDGTPPPVDTP--PRTARPRPAFTPRPVVGSERPRQEQLRGP 180


>gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo
           sapiens]
          Length = 180

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 53/170 (31%), Positives = 63/170 (37%), Gaps = 11/170 (6%)

Query: 81  GSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWV 140
           GS  PP ARG  P ET  P P    +PPL     PP  P   G P P     R   + W 
Sbjct: 15  GSHFPPAARGRLPGETLSPSPRAAALPPLQ--QRPPGAPGALGRPKPVSRGPRAGLREWP 72

Query: 141 PQP--PPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAP 198
            QP  P       + R      PG     T    P +       +T+S    SPG PA  
Sbjct: 73  QQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGL 132

Query: 199 RARR--RLGSGPDRELRKPEEPENGEPTAAATAR---RSKRERREEDRAP 243
              R  R   G    +  P  P    P  A T R    S+R R+E+ R P
Sbjct: 133 HRSREPRPQDGTPPPVDTP--PRTARPRPAFTPRPVVGSERPRQEQLRGP 180


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 100/435 (22%), Positives = 143/435 (32%), Gaps = 117/435 (26%)

Query: 53  PLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAG 112
           PLP+  + P N +  ++      E  +LGS        V  PE+ +P P  PL P  P  
Sbjct: 110 PLPEHQKIPCNSAEPKSIPALSMETQKLGS--------VLSPESPKPTPLTPLEPQKPGS 161

Query: 113 SLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLR 172
            + P        P P P   +    +  P+PP        ++L+    P          +
Sbjct: 162 VVSPELQ----TPLPSPEPSKPA-SVSSPEPPKSVPVCESQKLAPVPSPEPQ-------K 209

Query: 173 PRQVLCEKCKSTLSPPEASP--------GPPAAPRARRRLGSGPDRE-LRKPEEPENGEP 223
           P  V  E  K+TLS P+           GPP+A        S P+   L    EP    P
Sbjct: 210 PAPVSPESVKATLSNPKPQKQSHFPETLGPPSA--------SSPESPVLAASPEPWGPSP 261

Query: 224 TAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQ 283
            A+  +R+S R    E R P+      P       +P+ +      P+   GS +P  P 
Sbjct: 262 AASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPA---PAVSPGSWKPGPP- 317

Query: 284 QAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDS 343
                 GS  P   +          PSAS    K  +P P+ +  P      KP      
Sbjct: 318 ------GSPRPWKSN----------PSASSGPWKPAKPAPSVSPGP-----WKP------ 350

Query: 344 EHEPVYRAELVGELNGYLRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREG 403
                            +   SP P    P+   A   S SS     +KS P  P     
Sbjct: 351 -----------------IPSVSPGPWKPTPSVSSASWKS-SSVSPSSWKSPPASP----- 387

Query: 404 LAFLVSCPEGRADCASESACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQ 463
                                     E+  SG          LSP H  + P VS E R+
Sbjct: 388 --------------------------ESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRK 421

Query: 464 TVPPLTVRLHTQSVS 478
             PPL+  + + + S
Sbjct: 422 PGPPLSPEIRSPAGS 436


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 29/62 (46%), Positives = 29/62 (46%), Gaps = 6/62 (9%)

Query: 86  PPARGVQPPETTRPEPPPPLVPPLPAGSLPP-YPPYFEGAPFPHPLWLRDTYKLWVPQPP 144
           PPA     P    P PPPP VPP PA   PP  PP   G P P P     TY    P PP
Sbjct: 467 PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPP-----TYNPNFPPPP 521

Query: 145 PR 146
           PR
Sbjct: 522 PR 523



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 23/51 (45%), Positives = 27/51 (52%), Gaps = 8/51 (15%)

Query: 85  PPPARGVQPPETT-RPE--PPPPLVPPLPAGSLPPYPPYFEGAP---FPHP 129
           PPP  G  PP  T  P   PPPP +PP  A  +PP+PP   G P   +P P
Sbjct: 500 PPPTPGYPPPPPTYNPNFPPPPPRLPPTHA--VPPHPPPGLGLPPASYPPP 548



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 25/62 (40%), Positives = 30/62 (48%), Gaps = 6/62 (9%)

Query: 84  SPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQP 143
           +PPP     PP +    PPP + PP P G  PP P Y    P P P  L  T+ +  P P
Sbjct: 481 NPPPPPVPPPPASF---PPPAIPPPTP-GYPPPPPTYNPNFP-PPPPRLPPTHAV-PPHP 534

Query: 144 PP 145
           PP
Sbjct: 535 PP 536



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 37/126 (29%), Positives = 48/126 (38%), Gaps = 30/126 (23%)

Query: 48  LPPLAPLPQVDES-PVNDSHGRAPEEGDAE--------VMQLGSSSPPPARG-------- 90
           L P   +PQV +S P   S    P++ D +          Q    SP P+          
Sbjct: 279 LQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVV 338

Query: 91  VQPPETTR-PEPPPPLV-------PPLPAGSLPP--YPPYFEG---APFPHPLWLRDTYK 137
           V P E  +  EPPPP +       PPLP    PP   PP       A  P P+   D  K
Sbjct: 339 VSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPK 398

Query: 138 LWVPQP 143
           + +P P
Sbjct: 399 VQIPPP 404



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 19/53 (35%), Positives = 21/53 (39%), Gaps = 13/53 (24%)

Query: 85  PPPARGVQPPETTRPEPPPPL--------VPPLPAGSLPPYPPYFEGAPFPHP 129
           PPP   + P     P PPP L         P +P G  PP PP     P P P
Sbjct: 518 PPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPP-----PIPPP 565



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 4/36 (11%)

Query: 85  PPPARGV----QPPETTRPEPPPPLVPPLPAGSLPP 116
           PPP  G+     PP    P   PP+ PP+P   +PP
Sbjct: 534 PPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 4/74 (5%)

Query: 49  PPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPP-PARGVQPPETTRPEP--PPPL 105
           PP  P  +    P+  +H   P+        LG + PP P      P+   P P  P P+
Sbjct: 352 PPKIPKIETTHPPLPPAHP-PPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPV 410

Query: 106 VPPLPAGSLPPYPP 119
             P P    PP PP
Sbjct: 411 HQPPPLPHRPPPPP 424



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 48  LPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSS-PPPARGVQ----PPETTRPEPP 102
           LPP  P P   + P+  + G A   G  +   L     PPPA        PP   RP PP
Sbjct: 365 LPPAHPPPD-RKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPP 423

Query: 103 PP 104
           PP
Sbjct: 424 PP 425


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 34/85 (40%), Positives = 35/85 (41%), Gaps = 14/85 (16%)

Query: 46  FGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETT-RPEPPPP 104
           FG PPL PLP     PV    G  P  G           PPP +G  PP     P PP P
Sbjct: 284 FGQPPLGPLPPGPPPPVP---GYGPPPGP----------PPPQQGPPPPPGPFPPRPPGP 330

Query: 105 LVPPLPAGSLPPYPPYFEGAPFPHP 129
           L PPL     P  P    GAP P P
Sbjct: 331 LGPPLTLAPPPHLPGPPPGAPPPAP 355



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 21/50 (42%), Positives = 21/50 (42%), Gaps = 3/50 (6%)

Query: 80  LGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHP 129
           LG   PP   G  PP    P   PPL  P   G  PP P  F G PF  P
Sbjct: 241 LGPPGPPGPPGPPPPGQVLP---PPLAGPPNRGDRPPPPVLFPGQPFGQP 287



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 36/120 (30%), Positives = 40/120 (33%), Gaps = 25/120 (20%)

Query: 81  GSSSPPPARGVQPPETTRP-----EPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDT 135
           G   PPP   V PP    P      PPPP++ P      PP  P   G P P P      
Sbjct: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVP-----G 302

Query: 136 YKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPP 195
           Y      PPP+            R PG L                   TL+PP   PGPP
Sbjct: 303 YGPPPGPPPPQQGPPPPPGPFPPRPPGPL---------------GPPLTLAPPPHLPGPP 347



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 20/52 (38%), Positives = 20/52 (38%), Gaps = 15/52 (28%)

Query: 94  PETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPP 145
           P    P  PPP   P PAG  PP PP     P P P           P PPP
Sbjct: 218 PGPAGPGGPPP---PFPAGQTPPRPPLGPPGP-PGP-----------PGPPP 254


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 77/395 (19%), Positives = 123/395 (31%), Gaps = 32/395 (8%)

Query: 85  PPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPF----PHPLWLRDTYKLWV 140
           P P    +P  TT  EP P  +   P     P P   + AP     P P   ++      
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275

Query: 141 PQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRA 200
            +P P T K      +++         T    P     +K   T +P E +P  P  P  
Sbjct: 276 KEPAPTTTKEPAPTTTKS-------APTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPTP 327

Query: 201 RRRLGSGPDRELRKPEEPENGEPTA----AATARRSKRERREEDRAPAEQVPRSPVI--K 254
                  P  +   P  P+   PTA    A T  +       ++ AP      SP    +
Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387

Query: 255 ISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIP 314
            + +T +      K P+       P  P++       +      +E        P+ + P
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447

Query: 315 KLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSP---APCAD 371
           K     P P     P P    KP      E  P    E        L  ++P   AP   
Sbjct: 448 K----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503

Query: 372 GPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEA 431
                        +  ++   + P+ P      A   + P+  A    +    +   + A
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563

Query: 432 RSSGSEGTPADTGDLSPGHGASAPSVSREARQTVP 466
            +     TP +T   +P    +AP+  +E   T P
Sbjct: 564 PT-----TPKETAPTTP--KGTAPTTLKEPAPTTP 591



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 59/287 (20%), Positives = 85/287 (29%), Gaps = 17/287 (5%)

Query: 53  PLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAG 112
           P P   + P   +  +       E        P P    +P  TT  EP P      P  
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399

Query: 113 SLPPYPPYFEGAPF----PHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILST 168
           +  P P   + AP     P P   ++       +P P T K+      +   P      T
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP------T 453

Query: 169 IRLRPRQVLCEKCKSTLSPPEASPGPP--AAPRARRRLGSGPDRELRKPEEPENGEPTAA 226
               P     +K   T +P E +P  P   AP   ++L      +L  P  PE   PT  
Sbjct: 454 TPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTP 511

Query: 227 ATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPS-RVHGSLEPFRPQQ- 284
                +  E       P E  P +P      +  +      K P+        P  P++ 
Sbjct: 512 EELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570

Query: 285 APQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPP 331
           AP       P  L   +   P       +       P     D P P
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 61/286 (21%), Positives = 88/286 (30%), Gaps = 40/286 (13%)

Query: 50  PLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPP------ 103
           P  P P   E P   +   A      E        P P    +P  TT  E  P      
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 578

Query: 104 -PLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPG 162
            P     PA + P  P   E A    P   ++       +P P T K T     +   P 
Sbjct: 579 APTTLKEPAPTTPKKPAPKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP- 633

Query: 163 RLILSTIRLRPRQVLCEKCKSTL-----SPPEASPGPPAAPRARRRLGSGPDRELRKPEE 217
                     P++      K T       P   +P  PA          GP         
Sbjct: 634 --------TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 685

Query: 218 PENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKIS-YSTPQGKGEVVKIPSRVHGS 276
           P   + TA  T    K       + PA   P +P    S  STP       K P+ +H S
Sbjct: 686 PTTPKETAPTT---PKEPAPTTPKKPAPTTPETPPPTTSEVSTP----TTTKEPTTIHKS 738

Query: 277 LEPFRPQQAPQDDGSQDPEVLDRESRD---RPSCAPSASIPKLKLT 319
            +    +  P+      P+ L+   ++     +  P+A+ P++  T
Sbjct: 739 PD----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 77/395 (19%), Positives = 123/395 (31%), Gaps = 32/395 (8%)

Query: 85  PPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPF----PHPLWLRDTYKLWV 140
           P P    +P  TT  EP P  +   P     P P   + AP     P P   ++      
Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 316

Query: 141 PQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRA 200
            +P P T K      +++         T    P     +K   T +P E +P  P  P  
Sbjct: 317 KEPAPTTTKEPAPTTTKS-------APTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPTP 368

Query: 201 RRRLGSGPDRELRKPEEPENGEPTA----AATARRSKRERREEDRAPAEQVPRSPVI--K 254
                  P  +   P  P+   PTA    A T  +       ++ AP      SP    +
Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428

Query: 255 ISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIP 314
            + +T +      K P+       P  P++       +      +E        P+ + P
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488

Query: 315 KLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSP---APCAD 371
           K     P P     P P    KP      E  P    E        L  ++P   AP   
Sbjct: 489 K----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 544

Query: 372 GPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEA 431
                        +  ++   + P+ P      A   + P+  A    +    +   + A
Sbjct: 545 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604

Query: 432 RSSGSEGTPADTGDLSPGHGASAPSVSREARQTVP 466
            +     TP +T   +P    +AP+  +E   T P
Sbjct: 605 PT-----TPKETAPTTP--KGTAPTTLKEPAPTTP 632



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 59/287 (20%), Positives = 85/287 (29%), Gaps = 17/287 (5%)

Query: 53  PLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAG 112
           P P   + P   +  +       E        P P    +P  TT  EP P      P  
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440

Query: 113 SLPPYPPYFEGAPF----PHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILST 168
           +  P P   + AP     P P   ++       +P P T K+      +   P      T
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP------T 494

Query: 169 IRLRPRQVLCEKCKSTLSPPEASPGPP--AAPRARRRLGSGPDRELRKPEEPENGEPTAA 226
               P     +K   T +P E +P  P   AP   ++L      +L  P  PE   PT  
Sbjct: 495 TPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTP 552

Query: 227 ATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPS-RVHGSLEPFRPQQ- 284
                +  E       P E  P +P      +  +      K P+        P  P++ 
Sbjct: 553 EELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611

Query: 285 APQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPP 331
           AP       P  L   +   P       +       P     D P P
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 61/286 (21%), Positives = 88/286 (30%), Gaps = 40/286 (13%)

Query: 50  PLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPP------ 103
           P  P P   E P   +   A      E        P P    +P  TT  E  P      
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619

Query: 104 -PLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPG 162
            P     PA + P  P   E A    P   ++       +P P T K T     +   P 
Sbjct: 620 APTTLKEPAPTTPKKPAPKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP- 674

Query: 163 RLILSTIRLRPRQVLCEKCKSTL-----SPPEASPGPPAAPRARRRLGSGPDRELRKPEE 217
                     P++      K T       P   +P  PA          GP         
Sbjct: 675 --------TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 726

Query: 218 PENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKIS-YSTPQGKGEVVKIPSRVHGS 276
           P   + TA  T    K       + PA   P +P    S  STP       K P+ +H S
Sbjct: 727 PTTPKETAPTT---PKEPAPTTPKKPAPTTPETPPPTTSEVSTP----TTTKEPTTIHKS 779

Query: 277 LEPFRPQQAPQDDGSQDPEVLDRESRD---RPSCAPSASIPKLKLT 319
            +    +  P+      P+ L+   ++     +  P+A+ P++  T
Sbjct: 780 PD----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 77/395 (19%), Positives = 123/395 (31%), Gaps = 32/395 (8%)

Query: 85  PPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPF----PHPLWLRDTYKLWV 140
           P P    +P  TT  EP P  +   P     P P   + AP     P P   ++      
Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368

Query: 141 PQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRA 200
            +P P T K      +++         T    P     +K   T +P E +P  P  P  
Sbjct: 369 KEPAPTTTKEPAPTTTKS-------APTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPTP 420

Query: 201 RRRLGSGPDRELRKPEEPENGEPTA----AATARRSKRERREEDRAPAEQVPRSPVI--K 254
                  P  +   P  P+   PTA    A T  +       ++ AP      SP    +
Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480

Query: 255 ISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIP 314
            + +T +      K P+       P  P++       +      +E        P+ + P
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540

Query: 315 KLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSP---APCAD 371
           K     P P     P P    KP      E  P    E        L  ++P   AP   
Sbjct: 541 K----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 596

Query: 372 GPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEA 431
                        +  ++   + P+ P      A   + P+  A    +    +   + A
Sbjct: 597 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656

Query: 432 RSSGSEGTPADTGDLSPGHGASAPSVSREARQTVP 466
            +     TP +T   +P    +AP+  +E   T P
Sbjct: 657 PT-----TPKETAPTTP--KGTAPTTLKEPAPTTP 684



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 59/287 (20%), Positives = 85/287 (29%), Gaps = 17/287 (5%)

Query: 53  PLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAG 112
           P P   + P   +  +       E        P P    +P  TT  EP P      P  
Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492

Query: 113 SLPPYPPYFEGAPF----PHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILST 168
           +  P P   + AP     P P   ++       +P P T K+      +   P      T
Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP------T 546

Query: 169 IRLRPRQVLCEKCKSTLSPPEASPGPP--AAPRARRRLGSGPDRELRKPEEPENGEPTAA 226
               P     +K   T +P E +P  P   AP   ++L      +L  P  PE   PT  
Sbjct: 547 TPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTP 604

Query: 227 ATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPS-RVHGSLEPFRPQQ- 284
                +  E       P E  P +P      +  +      K P+        P  P++ 
Sbjct: 605 EELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663

Query: 285 APQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPP 331
           AP       P  L   +   P       +       P     D P P
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 61/286 (21%), Positives = 88/286 (30%), Gaps = 40/286 (13%)

Query: 50  PLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPP------ 103
           P  P P   E P   +   A      E        P P    +P  TT  E  P      
Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671

Query: 104 -PLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPG 162
            P     PA + P  P   E A    P   ++       +P P T K T     +   P 
Sbjct: 672 APTTLKEPAPTTPKKPAPKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP- 726

Query: 163 RLILSTIRLRPRQVLCEKCKSTL-----SPPEASPGPPAAPRARRRLGSGPDRELRKPEE 217
                     P++      K T       P   +P  PA          GP         
Sbjct: 727 --------TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 778

Query: 218 PENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKIS-YSTPQGKGEVVKIPSRVHGS 276
           P   + TA  T    K       + PA   P +P    S  STP       K P+ +H S
Sbjct: 779 PTTPKETAPTT---PKEPAPTTPKKPAPTTPETPPPTTSEVSTP----TTTKEPTTIHKS 831

Query: 277 LEPFRPQQAPQDDGSQDPEVLDRESRD---RPSCAPSASIPKLKLT 319
            +    +  P+      P+ L+   ++     +  P+A+ P++  T
Sbjct: 832 PD----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 77/395 (19%), Positives = 123/395 (31%), Gaps = 32/395 (8%)

Query: 85  PPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPF----PHPLWLRDTYKLWV 140
           P P    +P  TT  EP P  +   P     P P   + AP     P P   ++      
Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409

Query: 141 PQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRA 200
            +P P T K      +++         T    P     +K   T +P E +P  P  P  
Sbjct: 410 KEPAPTTTKEPAPTTTKS-------APTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPTP 461

Query: 201 RRRLGSGPDRELRKPEEPENGEPTA----AATARRSKRERREEDRAPAEQVPRSPVI--K 254
                  P  +   P  P+   PTA    A T  +       ++ AP      SP    +
Sbjct: 462 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 521

Query: 255 ISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIP 314
            + +T +      K P+       P  P++       +      +E        P+ + P
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581

Query: 315 KLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSP---APCAD 371
           K     P P     P P    KP      E  P    E        L  ++P   AP   
Sbjct: 582 K----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 637

Query: 372 GPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEA 431
                        +  ++   + P+ P      A   + P+  A    +    +   + A
Sbjct: 638 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697

Query: 432 RSSGSEGTPADTGDLSPGHGASAPSVSREARQTVP 466
            +     TP +T   +P    +AP+  +E   T P
Sbjct: 698 PT-----TPKETAPTTP--KGTAPTTLKEPAPTTP 725



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 59/287 (20%), Positives = 85/287 (29%), Gaps = 17/287 (5%)

Query: 53  PLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAG 112
           P P   + P   +  +       E        P P    +P  TT  EP P      P  
Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533

Query: 113 SLPPYPPYFEGAPF----PHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILST 168
           +  P P   + AP     P P   ++       +P P T K+      +   P      T
Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP------T 587

Query: 169 IRLRPRQVLCEKCKSTLSPPEASPGPP--AAPRARRRLGSGPDRELRKPEEPENGEPTAA 226
               P     +K   T +P E +P  P   AP   ++L      +L  P  PE   PT  
Sbjct: 588 TPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTP 645

Query: 227 ATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPS-RVHGSLEPFRPQQ- 284
                +  E       P E  P +P      +  +      K P+        P  P++ 
Sbjct: 646 EELAPTTPE-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704

Query: 285 APQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPP 331
           AP       P  L   +   P       +       P     D P P
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 61/286 (21%), Positives = 88/286 (30%), Gaps = 40/286 (13%)

Query: 50  PLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPP------ 103
           P  P P   E P   +   A      E        P P    +P  TT  E  P      
Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712

Query: 104 -PLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPG 162
            P     PA + P  P   E A    P   ++       +P P T K T     +   P 
Sbjct: 713 APTTLKEPAPTTPKKPAPKELA----PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP- 767

Query: 163 RLILSTIRLRPRQVLCEKCKSTL-----SPPEASPGPPAAPRARRRLGSGPDRELRKPEE 217
                     P++      K T       P   +P  PA          GP         
Sbjct: 768 --------TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 819

Query: 218 PENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKIS-YSTPQGKGEVVKIPSRVHGS 276
           P   + TA  T    K       + PA   P +P    S  STP       K P+ +H S
Sbjct: 820 PTTPKETAPTT---PKEPAPTTPKKPAPTTPETPPPTTSEVSTP----TTTKEPTTIHKS 872

Query: 277 LEPFRPQQAPQDDGSQDPEVLDRESRD---RPSCAPSASIPKLKLT 319
            +    +  P+      P+ L+   ++     +  P+A+ P++  T
Sbjct: 873 PD----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 59/295 (20%), Positives = 110/295 (37%), Gaps = 37/295 (12%)

Query: 188 PEASPGPPAAPRARRRLGSGPDRELRKPEEP-ENGEPTAAATARRSKRERREEDRAPAEQ 246
           P +S  PP+AP  ++ LG+ P ++  + ++P E+ E ++  +   S+ E++   +A   +
Sbjct: 288 PYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSK 347

Query: 247 VPRSP------VIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRE 300
               P          S S+     E  + PS+  G+ +          + S  P V  + 
Sbjct: 348 ATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTK----------NSSNKPAVTTKS 397

Query: 301 SRDRPSCAPSASIPKLKLTRPVPAGADLPPPKI--RLKPHRLGDSEHEPVYRAELVGELN 358
              +P+ AP          +PV  G  L   K            SE E   +     +  
Sbjct: 398 PAVKPAAAPK---------QPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPK 448

Query: 359 GYLRDSSPAPCADGPAG---GLADLSSGSSGEDDD------FKSCPQGPQGREGLAFLVS 409
              + +   P    P G     +D  S SS E+++       K  PQ   G    +   S
Sbjct: 449 ATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPAS 508

Query: 410 CPEGRADCASESACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQT 464
             +G+A+ ++ S+    S +E      +G+P      + G  A      + A+ +
Sbjct: 509 AKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNS 563



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 54/270 (20%), Positives = 86/270 (31%), Gaps = 28/270 (10%)

Query: 214 KPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRV 273
           KP+      P   A +  S  +   ED  P  Q P+   + +   T          P   
Sbjct: 151 KPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIA 210

Query: 274 HGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKI 333
           +G       + A     S      D    ++ +  P  ++PK ++    P  A   P + 
Sbjct: 211 NG-------KAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTR- 262

Query: 334 RLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGGL--------------AD 379
           +        S+ E   +  +  +   Y   S P P A  P   L               +
Sbjct: 263 KSSSSEDSSSDEEEEQKKPMKNKPGPY--SSVPPPSAPPPKKSLGTQPPKKAVEKQQPVE 320

Query: 380 LSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGSEGT 439
            S  SS E D      + P  +  ++   + P      A  S+ SSDS D +    +   
Sbjct: 321 SSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDS-DSSEDDEAPSK 379

Query: 440 PADTGDLS---PGHGASAPSVSREARQTVP 466
           PA T   S   P     +P+V   A    P
Sbjct: 380 PAGTTKNSSNKPAVTTKSPAVKPAAAPKQP 409



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 5/91 (5%)

Query: 370 ADGPAGGLADLSSGSSGEDDDFKSCP--QGPQGREGL--AFLVSCPEGRADC-ASESACS 424
           A+GP    A   + SS  +D  +     QGP  ++    A  V  P G+A   ASES+ S
Sbjct: 70  ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSS 129

Query: 425 SDSLDEARSSGSEGTPADTGDLSPGHGASAP 455
            +S D+      +  P   G       A AP
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAP 160


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 62/248 (25%), Positives = 83/248 (33%), Gaps = 34/248 (13%)

Query: 93  PPETTRPEPPP---PLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIK 149
           PPE +   PPP   P  PP  A  L P P     +P P  L L    +     PPP    
Sbjct: 443 PPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESP 502

Query: 150 RTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPD 209
            +    S    P                    +S LSPPE SP  PA       L   P+
Sbjct: 503 LSPPPESSPFSPLE------------------ESPLSPPEESPPSPA---LETPLSPPPE 541

Query: 210 RELRKP---EEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEV 266
                P   E P +  P    T+   +  R      P E+ P SP  + S  +P  +   
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLS---PPPEESPMSPPPEESPMSPPPEASR 598

Query: 267 VKIPSRVHGSLEP---FRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVP 323
           +  P      L P     P   P +     P   D      P  +P +  P++    P+P
Sbjct: 599 L-FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657

Query: 324 AGADLPPP 331
             + L PP
Sbjct: 658 VVSRLSPP 665



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 71/276 (25%), Positives = 96/276 (34%), Gaps = 55/276 (19%)

Query: 50  PLAPLPQ-------VDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPP 102
           P +PLP+       ++ESP++      PEE           SPPP      P    P  P
Sbjct: 475 PASPLPEALHLSRPLEESPLSPP----PEESPL--------SPPPESSPFSPLEESPLSP 522

Query: 103 PPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPG 162
           P   PP PA   P  PP  E +P   P      ++     PPP  +            P 
Sbjct: 523 PEESPPSPALETPLSPPP-EASPLSPP------FEESPLSPPPEEL------------PT 563

Query: 163 RLILSTIRLRPRQVLCEKCKSTLS-PPEASPGPPAAPRARRRLGSGPDRELRKPEEPENG 221
                  RL P        +S +S PPE SP  P  P A R      +  L  P E    
Sbjct: 564 SPPPEASRLSPPPE-----ESPMSPPPEESPMSP-PPEASRLFPPFEESPLSPPPEESPL 617

Query: 222 EPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFR 281
            P   A +R S          P E+ P SP  ++S  +P      + + SR+    E   
Sbjct: 618 SPPPEA-SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP------LPVVSRLSPPPEESP 670

Query: 282 PQQAPQDDGSQDPEVLDRES---RDRPSCAPSASIP 314
               P++  +  P    R S    D P+  P    P
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 52/178 (29%), Positives = 68/178 (38%), Gaps = 49/178 (27%)

Query: 47   GLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPP-L 105
            GL P  P P    +P   SH         ++ + GS + P A   QPP T RP+PPPP  
Sbjct: 2346 GLRPQEPPPAQALAPSPPSH--------PDIFRPGSYTDPYA---QPPLTPRPQPPPPES 2394

Query: 106  VPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLI 165
               LP  SLP         PF             VP  P        +  S ++ P    
Sbjct: 2395 CCALPPRSLP-------SDPFSR-----------VPASP--------QSQSSSQSP---- 2424

Query: 166  LSTIRLRPRQVLCEK-CKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGE 222
                 L PR +  E  C S ++P   SP P + P +R +    P   L KP  P+  E
Sbjct: 2425 -----LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ-SRDPFAPLHKPPRPQPPE 2476



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 36/117 (30%), Positives = 44/117 (37%), Gaps = 8/117 (6%)

Query: 30   RSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPAR 89
            + F  +L   T KS L  L  L       E P    H       + +V QL  S+PPP  
Sbjct: 4858 KQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQ--HSYTYNVSNLDVRQL--SAPPPEE 4913

Query: 90   GVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPR 146
               PP    P P  P  P  P   LP  P      P P PL L  + +   P+P  R
Sbjct: 4914 PSPPPSPLAPSPASP--PTEPLVELPTEP--LAEPPVPSPLPLASSPESARPKPRAR 4966



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 39/144 (27%), Positives = 54/144 (37%), Gaps = 15/144 (10%)

Query: 36   LLDCTKKSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDA----EVMQLGSSSPPPARGV 91
            LL C  + G F  P   PL ++   P      R P    A     V+     +PPP+   
Sbjct: 4256 LLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQ 4315

Query: 92   QPPETTR-PEPPPPL-----VPPLPAGSLPPYPPYFEGAP---FPHPLWLRDTY--KLWV 140
            +P   ++ P P   L     +PP   G+  P  P  E  P    P    L DT   K   
Sbjct: 4316 EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLG 4375

Query: 141  PQPPPRTIKRTRRRLSRNRDPGRL 164
            P  PP  +  T++    +  PG L
Sbjct: 4376 PWDPPDNLAETQKPEQSSLVPGHL 4399



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 75/307 (24%), Positives = 108/307 (35%), Gaps = 46/307 (14%)

Query: 50  PLAPLPQVDES---PVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQ--PPETTRPEPPPP 104
           P++P P+V      PV       PEE           SPPP       PPE +R  PPP 
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPL--------SPPPEESPTSPPPEASRLSPPPE 694

Query: 105 LVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRD---- 160
             P  P     P  P  E +    P  L ++  L +P+ P    +     LS   +    
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLP--LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752

Query: 161 ---PGRLILSTIRLRP-------RQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDR 210
              P    LS     P          LC   +     P+A  GP  +P+    L   P  
Sbjct: 753 SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQP-EELHLSPQT 810

Query: 211 E----LRKPEEP-ENGEPTAAATARRSKR---ERREEDRAPAEQVPRSPVIKISYSTPQG 262
           E       PEEP  + +P  +  + +S+      R E+   + ++ + P+       P+ 
Sbjct: 811 EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870

Query: 263 KG------EVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKL 316
            G      E+   P     SL P   + A  + G      L  E    PS  PS S P+L
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLS-PQL 929

Query: 317 KLTRPVP 323
               P+P
Sbjct: 930 MPPDPLP 936



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 49   PPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLV-P 107
            P L+PL ++ E P        PE   A  +     SPPP         T PEP PP++ P
Sbjct: 949  PALSPLGEL-EYPFGAKGDSDPESPLAAPILETPISPPPEANC-----TDPEPVPPMILP 1002

Query: 108  PLPAGSLPPYPP 119
            P P   + P  P
Sbjct: 1003 PSPGSPVGPASP 1014


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 70/292 (23%), Positives = 107/292 (36%), Gaps = 55/292 (18%)

Query: 56  QVDESPVNDSHGRAPEEGDAEVMQLGSSSP--PPARGVQPPETTRPEP---PPPLVPPLP 110
           Q D SP   SHG+ P  G   + +  S  P  PPA+   PP+   P+P   P    PPL 
Sbjct: 423 QRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQ 482

Query: 111 AGSLPPYPPYFE--GAPFPHPLWLRDTYKLWVPQPP-----PRTIKRTRRRLSRNRDPGR 163
               P    +    G P   PL  R       PQ P     P T  + R+       PG 
Sbjct: 483 QRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG- 541

Query: 164 LILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEP 223
                                 +PP A   PPA+P  +R+  +GP +  R+        P
Sbjct: 542 ----------------------APPAAR--PPASPSPQRQ--AGPPQATRQTSVSGPAPP 575

Query: 224 TAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQ 283
            A+      ++ +    + P    P  P  + S + P        +P     + +  RP 
Sbjct: 576 KASGAPPGGQQRQGPPQKPPG---PAGPTRQASQAGP--------VPRTGPPTTQQPRP- 623

Query: 284 QAPQDDGSQDPEVLDRESRDRPSCAPSAS----IPKLKLTRPVPAGADLPPP 331
             P   G   P++  + S+D P  A +A+     P+L  ++ +    +LP P
Sbjct: 624 SGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEP 675



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 50/172 (29%), Positives = 65/172 (37%), Gaps = 28/172 (16%)

Query: 43  SGLFGLPPLAPLPQVDESPVN-----DSHGRAPEEGD------------AEVMQLGSSSP 85
           SGL G P  +PLPQ   SP +      S    P +G             A       +SP
Sbjct: 494 SGL-GPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552

Query: 86  PPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPP 145
            P R   PP+ TR        PP  +G+ PP     +G P   P     T +     P P
Sbjct: 553 SPQRQAGPPQATRQTSVSGPAPPKASGA-PPGGQQRQGPPQKPPGPAGPTRQASQAGPVP 611

Query: 146 RTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPP--EASPGPP 195
           RT   T ++  R   PG         RP+  L +K    + PP   A+ GPP
Sbjct: 612 RTGPPTTQQ-PRPSGPGP------AGRPKPQLAQKPSQDVPPPATAAAGGPP 656


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.134    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,545,403
Number of Sequences: 37866
Number of extensions: 2009491
Number of successful extensions: 21516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 332
Number of HSP's successfully gapped in prelim test: 1062
Number of HSP's that attempted gapping in prelim test: 11439
Number of HSP's gapped (non-prelim): 6365
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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