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Search of human proteins with 148727368
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
(1205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 2449 0.0
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 1125 0.0
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 1118 0.0
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 948 0.0
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 214 3e-55
gi|117190334 PHD finger protein 16 [Homo sapiens] 210 6e-54
gi|7662006 PHD finger protein 16 [Homo sapiens] 210 6e-54
gi|40556370 PHD finger protein 15 [Homo sapiens] 197 4e-50
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 195 2e-49
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 165 3e-40
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 164 5e-40
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 164 5e-40
gi|45504380 jumonji domain containing 2B [Homo sapiens] 114 7e-25
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 114 7e-25
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 114 7e-25
gi|98986459 jumonji domain containing 2A [Homo sapiens] 108 4e-23
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 105 2e-22
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 105 2e-22
gi|41350212 bromodomain containing 7 [Homo sapiens] 91 9e-18
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 77 1e-13
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 74 8e-13
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 74 8e-13
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens] 69 2e-11
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 69 3e-11
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 68 6e-11
gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens] 65 3e-10
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 64 9e-10
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 64 9e-10
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 64 1e-09
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 62 3e-09
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapiens]
Length = 1205
Score = 2449 bits (6347), Expect = 0.0
Identities = 1205/1205 (100%), Positives = 1205/1205 (100%)
Query: 1 MRKPRRKSRQNAEGRRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKI 60
MRKPRRKSRQNAEGRRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKI
Sbjct: 1 MRKPRRKSRQNAEGRRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKI 60
Query: 61 ITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKHASGTSFHLPQPSFR 120
ITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKHASGTSFHLPQPSFR
Sbjct: 61 ITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKHASGTSFHLPQPSFR 120
Query: 121 MVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVS 180
MVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVS
Sbjct: 121 MVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVS 180
Query: 181 ADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVH 240
ADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVH
Sbjct: 181 ADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVH 240
Query: 241 QECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIWIPEVC 300
QECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIWIPEVC
Sbjct: 241 QECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIWIPEVC 300
Query: 301 FANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFM 360
FANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFM
Sbjct: 301 FANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFM 360
Query: 361 KIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEE 420
KIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEE
Sbjct: 361 KIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEE 420
Query: 421 EEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIP 480
EEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIP
Sbjct: 421 EEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIP 480
Query: 481 SYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDE 540
SYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDE
Sbjct: 481 SYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDE 540
Query: 541 KTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLLRT 600
KTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLLRT
Sbjct: 541 KTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLLRT 600
Query: 601 TLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNL 660
TLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNL
Sbjct: 601 TLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNL 660
Query: 661 IVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLEDFY 720
IVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLEDFY
Sbjct: 661 IVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLEDFY 720
Query: 721 RFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLLRREINALRQ 780
RFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLLRREINALRQ
Sbjct: 721 RFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLLRREINALRQ 780
Query: 781 KLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLEP 840
KLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLEP
Sbjct: 781 KLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLEP 840
Query: 841 TGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRKVEEDELLEKSPLQLGNEPLQRLLS 900
TGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRKVEEDELLEKSPLQLGNEPLQRLLS
Sbjct: 841 TGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRKVEEDELLEKSPLQLGNEPLQRLLS 900
Query: 901 DNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRSPDRVLENGEDHGVAGSP 960
DNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRSPDRVLENGEDHGVAGSP
Sbjct: 901 DNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRSPDRVLENGEDHGVAGSP 960
Query: 961 ASPASIEEERHSRKRPRSRSCSESEGERSPQQEEETGMTNGFGKHTESGSDSECSLGLSG 1020
ASPASIEEERHSRKRPRSRSCSESEGERSPQQEEETGMTNGFGKHTESGSDSECSLGLSG
Sbjct: 961 ASPASIEEERHSRKRPRSRSCSESEGERSPQQEEETGMTNGFGKHTESGSDSECSLGLSG 1020
Query: 1021 GLAFEACSGLTPPKRSRGKPALSRVPFLEGVNGDSDYNGSGRSLLLPFEDRGDLEPLELV 1080
GLAFEACSGLTPPKRSRGKPALSRVPFLEGVNGDSDYNGSGRSLLLPFEDRGDLEPLELV
Sbjct: 1021 GLAFEACSGLTPPKRSRGKPALSRVPFLEGVNGDSDYNGSGRSLLLPFEDRGDLEPLELV 1080
Query: 1081 WAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFD 1140
WAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFD
Sbjct: 1081 WAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFD 1140
Query: 1141 NKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFV 1200
NKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFV
Sbjct: 1141 NKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFV 1200
Query: 1201 TSSYL 1205
TSSYL
Sbjct: 1201 TSSYL 1205
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2
[Homo sapiens]
Length = 1214
Score = 1125 bits (2909), Expect = 0.0
Identities = 620/1236 (50%), Positives = 800/1236 (64%), Gaps = 116/1236 (9%)
Query: 1 MRKPRRKSRQNAEG-RRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLK 59
+RK ++K RQ+ ++SPSP + SP RE ++YAQAQR+VEVD+ GR+HRISI+D L
Sbjct: 58 LRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLD 117
Query: 60 IITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKH----ASGTSFHLP 115
+++EDE ++ E SNKEN+E P KS K +K K+K+S H ++ T+ LP
Sbjct: 118 VVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLP 177
Query: 116 QPSFRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDG 175
+ +R ++ P+APP P +YYRYIEK E+LD EVEYDMDEED WLD++NE+R+ +G
Sbjct: 178 EVVYRELEQDT-PDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEG 236
Query: 176 HSLVSADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDIC 235
S + + FE L+DRLEKESY ES + G +L+DEDA CC+C D EC NSNVILFCD+C
Sbjct: 237 VSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMC 296
Query: 236 NLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIW 295
NLAVHQECYGVPYIPEGQWLCR CLQSPSR VDC LCPNKGGAFKQT DG WAHVVCA+W
Sbjct: 297 NLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALW 356
Query: 296 IPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQR 355
IPEVCFANTVFLEPI+ I++IPPARWKLTCYICKQ+G GA IQCHK NCYTAFHVTCAQ+
Sbjct: 357 IPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQ 416
Query: 356 AGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKE 415
AGL+MK+EP+RET NGT F+VRKTAYC+ H+PPG +ARR L
Sbjct: 417 AGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPG--SARRL-------------PALSH 461
Query: 416 GDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLA 475
+GEE+E +EEE E +G S +K KS++ +K+ K E+ + P+++
Sbjct: 462 SEGEEDE----DEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKR-----AAAPVVS 512
Query: 476 VPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQ 535
VP IP +RL+KI + L+ QRK+QFMQRLH+YW LKRQ+RNGVPL+RRL +HLQSQRN +Q
Sbjct: 513 VPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQ 572
Query: 536 --REQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMP 593
R+ ++K A+KE+LK WQ+LRHDLERARLL+ELIRKREKLKRE +KVQQ AME++L P
Sbjct: 573 VGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTP 632
Query: 594 FNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEE 653
F +LLR TL+ LQEKD +IF+EPV LSEVPDYL+ I KPMDF TM++ LE++ Y ++
Sbjct: 633 FLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDD 692
Query: 654 FEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPES 713
FEEDFNLIV+NC+KYNAKDTIF+RAAVRLR+ GGA+LR ARRQAE +G D E G H+P S
Sbjct: 693 FEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHS 752
Query: 714 PKLEDFYRFSWE--DVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLL 771
++ + + + + +++ EN+ HL E QLK LLE+LD V+A + S R+RR +++
Sbjct: 753 LAGDEATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMI 812
Query: 772 RREINALRQKLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSK 831
++E+ ALR+KLA +T +G GP S
Sbjct: 813 KKEMTALRRKLAHQ--------RETGRDGPERHGPSSRG-------------------SL 845
Query: 832 LPPPPTLEPTGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRK----VEEDELLEKSP 887
P P + G S +E+ S E N S P+ + R +++ P
Sbjct: 846 TPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPP 905
Query: 888 LQLGNEPLQRLLSDNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRSPDRV 947
+ G P NR S M P + G+P+ ++ K G RSP
Sbjct: 906 KRPGRPPK---------NRESQMTP-SHGGSPVGPPQLPIMSSLRQRKRG----RSP--- 948
Query: 948 LENGEDHGVAGSPASPASIEEERHSRKRPRSRSCSESEGERSPQQEEETGMTNGFGKHTE 1007
P+S + + ++ + P + G P ++ N
Sbjct: 949 -----------RPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSL-PR 996
Query: 1008 SGSDSECSLGLSGGLAFEACSGLTPPKRSRGKPALSRVPFLE-------GVNGDSDYNGS 1060
S SDSE S S A + S TP K+ RGKP+ SR F E G ++ G+
Sbjct: 997 SSSDSESSSSSSSSAASDRTS-TTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGT 1055
Query: 1061 GRSL--------------LLPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLH 1106
GR + L ++ L+ L+LVWAKCRGYPSYPALIIDPKMPREG+ H
Sbjct: 1056 GRGVGHSMVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFH 1115
Query: 1107 NGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLK 1166
+GVPIPVPPL+VLKLGEQ EA E L+LVLFFDNKRTWQWLPR K++PLGV +DK K
Sbjct: 1116 HGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEK 1175
Query: 1167 MLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFVTS 1202
MLEGRK++IRKSVQ+AY RA+ H S+V+G S TS
Sbjct: 1176 MLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETS 1211
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1
[Homo sapiens]
Length = 1220
Score = 1118 bits (2892), Expect = 0.0
Identities = 620/1242 (49%), Positives = 800/1242 (64%), Gaps = 122/1242 (9%)
Query: 1 MRKPRRKSRQNAEG-RRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLK 59
+RK ++K RQ+ ++SPSP + SP RE ++YAQAQR+VEVD+ GR+HRISI+D L
Sbjct: 58 LRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLD 117
Query: 60 IITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKH----ASGTSFHLP 115
+++EDE ++ E SNKEN+E P KS K +K K+K+S H ++ T+ LP
Sbjct: 118 VVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLP 177
Query: 116 QPSFRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDG 175
+ +R ++ P+APP P +YYRYIEK E+LD EVEYDMDEED WLD++NE+R+ +G
Sbjct: 178 EVVYRELEQDT-PDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEG 236
Query: 176 HSLVSADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDIC 235
S + + FE L+DRLEKESY ES + G +L+DEDA CC+C D EC NSNVILFCD+C
Sbjct: 237 VSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMC 296
Query: 236 NLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIW 295
NLAVHQECYGVPYIPEGQWLCR CLQSPSR VDC LCPNKGGAFKQT DG WAHVVCA+W
Sbjct: 297 NLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALW 356
Query: 296 IPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQR 355
IPEVCFANTVFLEPI+ I++IPPARWKLTCYICKQ+G GA IQCHK NCYTAFHVTCAQ+
Sbjct: 357 IPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQ 416
Query: 356 AGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKE 415
AGL+MK+EP+RET NGT F+VRKTAYC+ H+PPG +ARR L
Sbjct: 417 AGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPG--SARRL-------------PALSH 461
Query: 416 GDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLA 475
+GEE+E +EEE E +G S +K KS++ +K+ K E+ + P+++
Sbjct: 462 SEGEEDE----DEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKR-----AAAPVVS 512
Query: 476 VPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQ 535
VP IP +RL+KI + L+ QRK+QFMQRLH+YW LKRQ+RNGVPL+RRL +HLQSQRN +Q
Sbjct: 513 VPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQ 572
Query: 536 --REQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMP 593
R+ ++K A+KE+LK WQ+LRHDLERARLL+ELIRKREKLKRE +KVQQ AME++L P
Sbjct: 573 VGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTP 632
Query: 594 FNVLLRTTLDLLQEKDPAHIFAEPVNLS------EVPDYLEFISKPMDFSTMRRKLESHL 647
F +LLR TL+ LQEKD +IF+EPV LS EVPDYL+ I KPMDF TM++ LE++
Sbjct: 633 FLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLDHIKKPMDFFTMKQNLEAYR 692
Query: 648 YRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERG 707
Y ++FEEDFNLIV+NC+KYNAKDTIF+RAAVRLR+ GGA+LR ARRQAE +G D E G
Sbjct: 693 YLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETG 752
Query: 708 THLPESPKLEDFYRFSWE--DVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGART 765
H+P S ++ + + + + +++ EN+ HL E QLK LLE+LD V+A + S R+
Sbjct: 753 MHIPHSLAGDEATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRS 812
Query: 766 RRVRLLRREINALRQKLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDG 825
RR +++++E+ ALR+KLA +T +G GP
Sbjct: 813 RRAKMIKKEMTALRRKLAHQ--------RETGRDGPERHGPSSRG--------------- 849
Query: 826 DRDDSKLPPPPTLEPTGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRK----VEEDE 881
S P P + G S +E+ S E N S P+ + R +++
Sbjct: 850 ----SLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNP 905
Query: 882 LLEKSPLQLGNEPLQRLLSDNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQ 941
P + G P NR S M P + G+P+ ++ K G
Sbjct: 906 KTAGPPKRPGRPPK---------NRESQMTP-SHGGSPVGPPQLPIMSSLRQRKRG---- 951
Query: 942 RSPDRVLENGEDHGVAGSPASPASIEEERHSRKRPRSRSCSESEGERSPQQEEETGMTNG 1001
RSP P+S + + ++ + P + G P ++ N
Sbjct: 952 RSP--------------RPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRND 997
Query: 1002 FGKHTESGSDSECSLGLSGGLAFEACSGLTPPKRSRGKPALSRVPFLE-------GVNGD 1054
S SDSE S S A + S TP K+ RGKP+ SR F E G +
Sbjct: 998 CSL-PRSSSDSESSSSSSSSAASDRTS-TTPSKQGRGKPSFSRGTFPEDSSEDTSGTENE 1055
Query: 1055 SDYNGSGRSL--------------LLPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMP 1100
+ G+GR + L ++ L+ L+LVWAKCRGYPSYPALIIDPKMP
Sbjct: 1056 AYSVGTGRGVGHSMVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMP 1115
Query: 1101 REGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFDNKRTWQWLPRDKVLPLGVED 1160
REG+ H+GVPIPVPPL+VLKLGEQ EA E L+LVLFFDNKRTWQWLPR K++PLGV
Sbjct: 1116 REGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQ 1175
Query: 1161 TVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFVTS 1202
+DK KMLEGRK++IRKSVQ+AY RA+ H S+V+G S TS
Sbjct: 1176 DLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETS 1217
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 948 bits (2450), Expect = 0.0
Identities = 486/840 (57%), Positives = 607/840 (72%), Gaps = 43/840 (5%)
Query: 5 RRKSR--QNAEGRRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKIIT 62
RRK R + + R SP S+K SPTRETLTYAQAQR+VE++I+GRLHRISI+DPL+II
Sbjct: 2 RRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIIL 61
Query: 63 EDELTAQDITECNSNKENSEQPQFPGKSKK-PSSKGKKKESCSKHASGT---SFHLPQPS 118
ED+LTAQ+++ECNSNKENSE+P ++K+ +++ KKK A GT + LP+P
Sbjct: 62 EDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASALPEPK 121
Query: 119 FRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSL 178
R+V+ P AP P YY++IEK E+LD EVEYDMDEED AWL++VNEKR+ D
Sbjct: 122 VRIVEYS-PPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA 180
Query: 179 VSADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLA 238
VS FE L+DR EKES+ E++ G QQSLIDEDA CC+C+D EC NSNVILFCD+CNLA
Sbjct: 181 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA 240
Query: 239 VHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIWIPE 298
VHQECYGVPYIPEGQWLCR CLQS +RP DC+LCPNKGGAFK+T D W HVVCA+WIPE
Sbjct: 241 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE 300
Query: 299 VCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGL 358
V FANTVF+EPI+G+ NIPPARWKLTCY+CKQKG+GA IQCHK NCYTAFHVTCAQ+AGL
Sbjct: 301 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL 360
Query: 359 FMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDG 418
+MK+EP++E + GT F+VRKTAYC+ H+PPG + R ++ GD E +K G
Sbjct: 361 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGC--------TRRPLNIYGDVE-MKNGVC 411
Query: 419 EEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQ 478
+E S+K V SK+ +K K+ ++A + + LP + P
Sbjct: 412 RKE-----------------SSVKTVRSTSKV---RKKAKKAKKALAEPCAVLPTVCAPY 451
Query: 479 IPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQ 538
IP RLN+I + ++ QRK QF++R H+YWLLKR +RNG PL+RRL S LQSQR+++QRE
Sbjct: 452 IPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRSSQQREN 511
Query: 539 DEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLL 598
DE+ A KE+LKYWQ+LRHDLERARLLIEL+RKREKLKREQVKV+Q AMEL L P VLL
Sbjct: 512 DEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQVAMELRLTPLTVLL 571
Query: 599 RTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDF 658
R+ LD LQ+KDPA IFA+PV+L EVPDYL+ I PMDF+TMR++LE+ Y+ L EFEEDF
Sbjct: 572 RSVLDQLQDKDPARIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDF 631
Query: 659 NLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLED 718
+LI+ NCMKYNA+DT+F+RAAVRLRD GG +LR ARR+ ++IG + G HLPE P
Sbjct: 632 DLIIDNCMKYNARDTVFYRAAVRLRDQGGVVLRQARREVDSIGLEEASGMHLPERPAAAP 691
Query: 719 FYRFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLLRREINAL 778
FSWEDVD +L P NRAHL E QL+ELL+ LDL AM+SSG+R++R +LL++EI L
Sbjct: 692 RRPFSWEDVDRLLDPANRAHLGLEEQLRELLDMLDLTCAMKSSGSRSKRAKLLKKEIALL 751
Query: 779 RQKLAQ---PPPPQPPSLNKTVSNGELPAGPQGDAAV---LEQALQEEPEDDGDRDDSKL 832
R KL+Q P P P L +G GP+ V LE LQ DS++
Sbjct: 752 RNKLSQQHSQPLPTGPGLEGFEEDG-AALGPEAGEEVLPRLETLLQPRKRSRSTCGDSEV 810
Score = 217 bits (553), Expect = 5e-56
Identities = 133/287 (46%), Positives = 170/287 (59%), Gaps = 46/287 (16%)
Query: 948 LENGEDHGVAGSPASPASIEEERHSRKRPRSRS---CSESE-GERSPQQEEETGMTNGFG 1003
LE E+ G A P + + + +PR RS C +SE E SP + + G+TNGFG
Sbjct: 769 LEGFEEDGAALGPEAGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFG 828
Query: 1004 KHTESGSDSECSLGLSGGLAFEAC--------------------SGLTPPKRSRGKPALS 1043
G+ SE G GGL +A S PK RGKPAL
Sbjct: 829 -----GARSEQEPG--GGLGRKATPRRRCASESSISSSNSPLCDSSFNAPKCGRGKPALV 881
Query: 1044 RVPFLEGVNG------DSDYNGSGR--------SLLLPFEDRGD-LEPLELVWAKCRGYP 1088
R LE + + +Y + R S+ + + LEPL++VWAKC GYP
Sbjct: 882 RRHTLEDRSELISCIENGNYAKAARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYP 941
Query: 1089 SYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFDNKRTWQWL 1148
SYPALIIDPKMPR HNGV IP PPLDVLK+GE Q ++ EKLFLVLFFDNKR+WQWL
Sbjct: 942 SYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWL 1001
Query: 1149 PRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRG 1195
P+ K++PLG+++T+DKLKM+EGR +SIRK+V++A+DRAM HLSRV G
Sbjct: 1002 PKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHG 1048
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 214 bits (546), Expect = 3e-55
Identities = 158/511 (30%), Positives = 230/511 (45%), Gaps = 73/511 (14%)
Query: 84 PQFPGKSKKPSSKGKKKESCSKHASGTSFHLPQPSFRMVDSGIQPEAPPLPAAYYRYIEK 143
P PG +P ++ +E S +P +V SG +P P L R +
Sbjct: 87 PVSPGTIPQPVARVVSEEK--------SLMFIRPKKYIVSSGSEP--PELGYVDIRTLA- 135
Query: 144 PPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLE-SRSS 202
D+ YD+++ D AWL++ NE+ + G + T E +++ E+ Y + +
Sbjct: 136 -----DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAI 190
Query: 203 GAQQSL---IDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCC 259
++ L DED C VC + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 191 ETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC 250
Query: 260 LQSPSRPVDCILCPNKGGAFKQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPP 318
C+LCP KGGA K T G W HV CA+WIPEV + +EPI + +IP
Sbjct: 251 ALGVQ--PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPS 308
Query: 319 ARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVR 378
+RW L C +C +K GA+IQC NC TAFHVTCA GL MK ++ V+
Sbjct: 309 SRWALVCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMK-------TILAENDEVK 360
Query: 379 KTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVS 438
+YC HS S EE L +G +E E
Sbjct: 361 FKSYCPKHS-----------------SHRKPEESLGKGAAQENGAPECSPRN-------- 395
Query: 439 GSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQ 498
P + SL+Q EEA + + + + +N + + + +
Sbjct: 396 ------PLEPFASLEQ----NREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEE 445
Query: 499 FMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHD 558
+ L+ YW LKR+ PLI + N +REQD + L+ + LR D
Sbjct: 446 VVDFLYQYWKLKRKVNFNKPLIT---PKKDEEDNLAKREQD----VLFRRLQLFTHLRQD 498
Query: 559 LERARLLIELIRKREKLKREQVKVQQAAMEL 589
LER R L ++ +REK+KR KVQ+ L
Sbjct: 499 LERVRNLTYMVTRREKIKRSVCKVQEQIFNL 529
>gi|117190334 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 210 bits (535), Expect = 6e-54
Identities = 158/519 (30%), Positives = 228/519 (43%), Gaps = 85/519 (16%)
Query: 114 LPQPSFRMVDSGIQPEAPPLPAAYYRYIEKPPE---------DLDAEV-EYDMDEEDLAW 163
+PQPS R++ ++ P Y + P +L A V YD+D+ D+ W
Sbjct: 89 VPQPSLRIIAEKVKDVLFIRPRKYI-HCSSPDTTEPGYINIMELAASVCRYDLDDMDIFW 147
Query: 164 LDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLE-SRSSGAQQSL---IDEDAFCCVCL 219
L +NE G V + E V+ LE+ + + + ++ L DED C VC
Sbjct: 148 LQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCR 207
Query: 220 DDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAF 279
+ N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C+LCP KGGA
Sbjct: 208 SPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLGIY--PQCVLCPKKGGAL 265
Query: 280 KQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQ 338
K T G WAHV CA+WIPEV A +EPI I +IPP+RW L C +CK K GA IQ
Sbjct: 266 KTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLK-TGACIQ 324
Query: 339 CHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKG 398
C +C TAFHVTCA GL MK ++ V+ +YC HS
Sbjct: 325 CSIKSCITAFHVTCAFEHGLEMK-------TILDEGDEVKFKSYCLKHSQN--------- 368
Query: 399 DSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKK 458
++ GE E +E+ +A K K SL+ + +
Sbjct: 369 ---------------RQKLGEAEYPHHRAKEQSQA------------KSEKTSLRAQKLR 401
Query: 459 EPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVP 518
E EE + A +P+ ++ I +NYW LKR++ P
Sbjct: 402 ELEEEFYSLVRVEDVAAELGMPTLAVDFI----------------YNYWKLKRKSNFNKP 445
Query: 519 LIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKRE 578
L + + E K ++ ++ + LR DLER R L +I +REKLK
Sbjct: 446 L-------FPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLS 498
Query: 579 QVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEP 617
K+Q+ L++ N + L L + + + P
Sbjct: 499 HNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPP 537
>gi|7662006 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 210 bits (535), Expect = 6e-54
Identities = 158/519 (30%), Positives = 228/519 (43%), Gaps = 85/519 (16%)
Query: 114 LPQPSFRMVDSGIQPEAPPLPAAYYRYIEKPPE---------DLDAEV-EYDMDEEDLAW 163
+PQPS R++ ++ P Y + P +L A V YD+D+ D+ W
Sbjct: 89 VPQPSLRIIAEKVKDVLFIRPRKYI-HCSSPDTTEPGYINIMELAASVCRYDLDDMDIFW 147
Query: 164 LDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLE-SRSSGAQQSL---IDEDAFCCVCL 219
L +NE G V + E V+ LE+ + + + ++ L DED C VC
Sbjct: 148 LQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCR 207
Query: 220 DDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAF 279
+ N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C+LCP KGGA
Sbjct: 208 SPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLGIY--PQCVLCPKKGGAL 265
Query: 280 KQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQ 338
K T G WAHV CA+WIPEV A +EPI I +IPP+RW L C +CK K GA IQ
Sbjct: 266 KTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLK-TGACIQ 324
Query: 339 CHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKG 398
C +C TAFHVTCA GL MK ++ V+ +YC HS
Sbjct: 325 CSIKSCITAFHVTCAFEHGLEMK-------TILDEGDEVKFKSYCLKHSQN--------- 368
Query: 399 DSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKK 458
++ GE E +E+ +A K K SL+ + +
Sbjct: 369 ---------------RQKLGEAEYPHHRAKEQSQA------------KSEKTSLRAQKLR 401
Query: 459 EPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVP 518
E EE + A +P+ ++ I +NYW LKR++ P
Sbjct: 402 ELEEEFYSLVRVEDVAAELGMPTLAVDFI----------------YNYWKLKRKSNFNKP 445
Query: 519 LIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKRE 578
L + + E K ++ ++ + LR DLER R L +I +REKLK
Sbjct: 446 L-------FPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLS 498
Query: 579 QVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEP 617
K+Q+ L++ N + L L + + + P
Sbjct: 499 HNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPP 537
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 197 bits (502), Expect = 4e-50
Identities = 146/483 (30%), Positives = 220/483 (45%), Gaps = 77/483 (15%)
Query: 114 LPQPSFRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRV 173
+P+P R++ P A P++ P D YD+DE D WL+++N + +
Sbjct: 98 IPEPVVRILPPLEGPPAQASPSSTMLGEGSQP-DWPGGSRYDLDEIDAYWLELINSELKE 156
Query: 174 DGHSLVSADTFELLVDRLEKESYLE-SRSSGAQQSL---IDEDAFCCVCLDDECHNSNVI 229
+ T E +++ LE + +R+ Q+ L DED C VC E + N +
Sbjct: 157 MERPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEM 216
Query: 230 LFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDG-HWA 288
+FCD CN+ VHQ CYG+ +P G WLCR C C+LCP +GGA K T G W
Sbjct: 217 VFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQ--PKCLLCPKRGGALKPTRSGTKWV 274
Query: 289 HVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAF 348
HV CA+WIPEV +EPI I +IP +RW L+C +CK+ G IQC +C TAF
Sbjct: 275 HVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKE-CTGTCIQCSMPSCVTAF 333
Query: 349 HVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETG 408
HVTCA GL M+ ++ V+ ++C+ HS G PR+
Sbjct: 334 HVTCAFDHGLEMR-------TILADNDEVKFKSFCQEHSDGG----------PRN----- 371
Query: 409 DEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTP 468
E E + +Q G K++L+++ ++ EE +
Sbjct: 372 ---------------EPTSEPTEPSQAG--------EDLEKVTLRKQRLQQLEEDFYE-- 406
Query: 469 STLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQ 528
L P + RL+ + + F ++ YW LKR+A PL+ +
Sbjct: 407 -----LVEPAEVAERLDLAEALVDF---------IYQYWKLKRKANANQPLLTPKTDEVD 452
Query: 529 SQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAME 588
N Q+EQD + LK + LR DLER R L ++ +RE+ K K+Q+
Sbjct: 453 ---NLAQQEQD----VLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFH 505
Query: 589 LEL 591
L++
Sbjct: 506 LQM 508
Score = 32.0 bits (71), Expect = 3.6
Identities = 55/225 (24%), Positives = 79/225 (35%), Gaps = 23/225 (10%)
Query: 733 PENRAHL---SPEVQLKELLEKLD-LVSAMRSSGARTRRVRLLRREINALRQKLAQPPPP 788
P N H +P + +ELL+ + L+S MR R R L K PPPP
Sbjct: 551 PLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPP 610
Query: 789 QPPSLNKTVSNGELPAGPQGDAAVLEQALQEEP-EDDGDRDDSKLPPPPTLEPTGPAPSL 847
+ + P G A + Q P R S LP P G P L
Sbjct: 611 PQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPA---AGDCPIL 667
Query: 848 SEQESPPEPPTLKPINDSKPPSRFLKPRKVEEDELLEKSPLQLGNEPLQRLLSDNGINRL 907
+ ESPP P+ P + V D ++ +PL RL R
Sbjct: 668 ATPESPP------PLAPETPD----EAASVAADSDVQVPGPAASPKPLGRLRPP----RE 713
Query: 908 SLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRSPDRVLENGE 952
S + P P +G+G ++V ++ K + D +GE
Sbjct: 714 SKVTRRLPGARPDAGMGPPSAVA-ERPKVSLHFDTETDGYFSDGE 757
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 195 bits (496), Expect = 2e-49
Identities = 147/486 (30%), Positives = 215/486 (44%), Gaps = 73/486 (15%)
Query: 84 PQFPGKSKKPSSKGKKKESCSKHASGTSFHLPQPSFRMVDSGIQPEAPPLPAAYYRYIEK 143
P PG +P ++ +E S +P +V SG +P P L R +
Sbjct: 87 PVSPGTIPQPVARVVSEEK--------SLMFIRPKKYIVSSGSEP--PELGYVDIRTLA- 135
Query: 144 PPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLE-SRSS 202
D+ YD+++ D AWL++ NE+ + G + T E +++ E+ Y + +
Sbjct: 136 -----DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAI 190
Query: 203 GAQQSL---IDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCC 259
++ L DED C VC + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 191 ETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC 250
Query: 260 LQSPSRPVDCILCPNKGGAFKQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPP 318
C+LCP KGGA K T G W HV CA+WIPEV + +EPI + +IP
Sbjct: 251 ALGVQ--PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPS 308
Query: 319 ARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVR 378
+RW L C +C +K GA+IQC NC TAFHVTCA GL MK ++ V+
Sbjct: 309 SRWALVCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMK-------TILAENDEVK 360
Query: 379 KTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVS 438
+YC HS S EE L +G +E E
Sbjct: 361 FKSYCPKHS-----------------SHRKPEESLGKGAAQENGAPECSPRN-------- 395
Query: 439 GSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQ 498
P + SL+Q EEA + + + + +N + + + +
Sbjct: 396 ------PLEPFASLEQ----NREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEE 445
Query: 499 FMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHD 558
+ L+ YW LKR+ PLI + N +REQD + L+ + LR D
Sbjct: 446 VVDFLYQYWKLKRKVNFNKPLIT---PKKDEEDNLAKREQD----VLFRRLQLFTHLRQD 498
Query: 559 LERARL 564
LER +
Sbjct: 499 LERVMI 504
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 165 bits (417), Expect = 3e-40
Identities = 103/281 (36%), Positives = 138/281 (49%), Gaps = 37/281 (13%)
Query: 215 CCVCLDDECHNSNVILFCD--ICNLAVHQECYGVPYIPEGQWLCRCC-LQSPSRPVDCIL 271
CCVC D+ N +++CD C++AVHQ CYG+ +P G W CR C Q + V C L
Sbjct: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
Query: 272 CPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQK 331
CP+K GA K+T +G WAHVVCA++IPEV FAN + +EPI + +P R+ TCYIC+++
Sbjct: 68 CPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEEQ 126
Query: 332 G------LGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCE- 384
G GA + C++ C AFHVTCAQ AGL + E + + V+ YC+
Sbjct: 127 GRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLE-------VDNVKYCGYCKY 179
Query: 385 --------AHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGG 436
HS G G +G G + ++E E
Sbjct: 180 HFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHE---- 235
Query: 437 VSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVP 477
G K +K K LKQK KK PE PS L VP
Sbjct: 236 -RGQKKS--RKDKERLKQKHKKRPE----SPPSILTPPVVP 269
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 164 bits (415), Expect = 5e-40
Identities = 102/277 (36%), Positives = 144/277 (51%), Gaps = 43/277 (15%)
Query: 215 CCVCLDDECHNSNVILFCDI--CNLAVHQECYGVPYIPEGQWLCRCC-LQSPSRPVDCIL 271
CCVC D+ N +++CD C++AVHQ CYG+ +P G W CR C Q + V C L
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
Query: 272 CPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQK 331
CP+K GA K+T +G WAHVVCA++IPEV FAN +EPI + ++P R+ TCYIC ++
Sbjct: 85 CPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDEQ 143
Query: 332 G------LGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEA 385
G GA + C+K C AFHVTCAQ AGL + E NG V+ YC+
Sbjct: 144 GRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEG------NGA-DNVQYCGYCKY 196
Query: 386 HSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVP 445
H + + K S RS ++ + D E+E++ +E+ +
Sbjct: 197 HF---SKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKH------------ 241
Query: 446 KKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIPSY 482
KQK KK+PE +P+ +P L V +Y
Sbjct: 242 -------KQKHKKQPE----PSPALVPSLTVTTEKTY 267
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 164 bits (415), Expect = 5e-40
Identities = 102/277 (36%), Positives = 144/277 (51%), Gaps = 43/277 (15%)
Query: 215 CCVCLDDECHNSNVILFCDI--CNLAVHQECYGVPYIPEGQWLCRCC-LQSPSRPVDCIL 271
CCVC D+ N +++CD C++AVHQ CYG+ +P G W CR C Q + V C L
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
Query: 272 CPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQK 331
CP+K GA K+T +G WAHVVCA++IPEV FAN +EPI + ++P R+ TCYIC ++
Sbjct: 85 CPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDEQ 143
Query: 332 G------LGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEA 385
G GA + C+K C AFHVTCAQ AGL + E NG V+ YC+
Sbjct: 144 GRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEG------NGA-DNVQYCGYCKY 196
Query: 386 HSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVP 445
H + + K S RS ++ + D E+E++ +E+ +
Sbjct: 197 HF---SKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKH------------ 241
Query: 446 KKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIPSY 482
KQK KK+PE +P+ +P L V +Y
Sbjct: 242 -------KQKHKKQPE----PSPALVPSLTVTTEKTY 267
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 114 bits (284), Expect = 7e-25
Identities = 57/137 (41%), Positives = 78/137 (56%), Gaps = 6/137 (4%)
Query: 229 ILFCDICNLAVHQECYGV-PYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHW 287
++ C C L VH CYG+ P + W C C + + +C LC +GGA + T+D W
Sbjct: 757 LIACGKCCLQVHASCYGIRPELVNEGWTCSRCA-AHAWTAECCLCNLRGGALQMTTDRRW 815
Query: 288 AHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICK---QKGLGAAIQCHKVNC 344
HV+CAI +PE F N + P++ I IP RWKL C C+ +K GA IQC +C
Sbjct: 816 IHVICAIAVPEARFLNVIERHPVD-ISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHC 874
Query: 345 YTAFHVTCAQRAGLFMK 361
T+FHVTCA AG+ M+
Sbjct: 875 STSFHVTCAHAAGVLME 891
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 114 bits (284), Expect = 7e-25
Identities = 69/222 (31%), Positives = 97/222 (43%), Gaps = 27/222 (12%)
Query: 182 DTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQ 241
D+ L + ++S + +S +D CCVCL D +++ I+ CD C + VH+
Sbjct: 289 DSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHE 348
Query: 242 ECYGVPYIPEG-----------QWLCRCCL--QSPSRPVDCILCPNKGGAFKQTSDGHWA 288
CYGV + W C C SPS C LCPN+ G FK+T G W
Sbjct: 349 GCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPS----CELCPNQDGIFKETDAGRWV 404
Query: 289 HVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGL---GAAIQCHKVNCY 345
H+VCA+++P V F + L P+ + C C+ G I C C
Sbjct: 405 HIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCR 464
Query: 346 TAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEAHS 387
FHVTCAQ+ GL E E + F AYC+ H+
Sbjct: 465 AYFHVTCAQKEGLLS--EAAAEEDIADPFF-----AYCKQHA 499
Score = 35.0 bits (79), Expect = 0.43
Identities = 35/132 (26%), Positives = 55/132 (41%), Gaps = 17/132 (12%)
Query: 152 VEYDMDEEDLAWLDMVNEKRRVDGH---SLVSADTFELL----VDRLEKESYLESRSSGA 204
VEY+ E L L +N K R +G +L+ T + L + R KE + G
Sbjct: 656 VEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGT 715
Query: 205 QQ-SLIDEDAFCC-VCLDDECHNSNVILFCDICNLAVHQECYGVPY------IPEGQWLC 256
Q+ S + + C +C + H+ +++L CD C L H C P W C
Sbjct: 716 QKTSTLPAVLYSCGICKKN--HDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQC 773
Query: 257 RCCLQSPSRPVD 268
C Q+ S ++
Sbjct: 774 SECDQAGSSDME 785
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 114 bits (284), Expect = 7e-25
Identities = 69/222 (31%), Positives = 97/222 (43%), Gaps = 27/222 (12%)
Query: 182 DTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQ 241
D+ L + ++S + +S +D CCVCL D +++ I+ CD C + VH+
Sbjct: 289 DSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHE 348
Query: 242 ECYGVPYIPEG-----------QWLCRCCL--QSPSRPVDCILCPNKGGAFKQTSDGHWA 288
CYGV + W C C SPS C LCPN+ G FK+T G W
Sbjct: 349 GCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPS----CELCPNQDGIFKETDAGRWV 404
Query: 289 HVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGL---GAAIQCHKVNCY 345
H+VCA+++P V F + L P+ + C C+ G I C C
Sbjct: 405 HIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCR 464
Query: 346 TAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEAHS 387
FHVTCAQ+ GL E E + F AYC+ H+
Sbjct: 465 AYFHVTCAQKEGLLS--EAAAEEDIADPFF-----AYCKQHA 499
Score = 35.0 bits (79), Expect = 0.43
Identities = 35/132 (26%), Positives = 55/132 (41%), Gaps = 17/132 (12%)
Query: 152 VEYDMDEEDLAWLDMVNEKRRVDGH---SLVSADTFELL----VDRLEKESYLESRSSGA 204
VEY+ E L L +N K R +G +L+ T + L + R KE + G
Sbjct: 656 VEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGT 715
Query: 205 QQ-SLIDEDAFCC-VCLDDECHNSNVILFCDICNLAVHQECYGVPY------IPEGQWLC 256
Q+ S + + C +C + H+ +++L CD C L H C P W C
Sbjct: 716 QKTSTLPAVLYSCGICKKN--HDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQC 773
Query: 257 RCCLQSPSRPVD 268
C Q+ S ++
Sbjct: 774 SECDQAGSSDME 785
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 108 bits (269), Expect = 4e-23
Identities = 53/140 (37%), Positives = 79/140 (56%), Gaps = 6/140 (4%)
Query: 226 SNVILFCDICNLAVHQECYGVPYIPEGQ-WLCRCCLQSPSRPVDCILCPNKGGAFKQTSD 284
+++++ C C++ VH CYGVP + W+C C + + DC LC +GGA ++ +D
Sbjct: 732 TSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRC-SANALEEDCCLCSLRGGALQRAND 790
Query: 285 GHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICK---QKGLGAAIQCHK 341
W HV CA+ I E F N P++ + IP R+KL C CK ++ G +QC
Sbjct: 791 DRWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSH 849
Query: 342 VNCYTAFHVTCAQRAGLFMK 361
C TAFHV+CAQ AG+ M+
Sbjct: 850 GRCPTAFHVSCAQAAGVMMQ 869
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 105 bits (263), Expect = 2e-22
Identities = 57/141 (40%), Positives = 82/141 (58%), Gaps = 8/141 (5%)
Query: 226 SNVILFCDICNLAVHQECYGVPY--IPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTS 283
+++++ C C + VH CYG+P I +G WLC C ++ + +C LC +GGA KQT
Sbjct: 712 TSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRN-AWTAECCLCNLRGGALKQTK 769
Query: 284 DGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICK---QKGLGAAIQCH 340
+ WAHV+CA+ +PEV F N I+ + IP R KL C C+ ++ GA IQC
Sbjct: 770 NNKWAHVMCAVAVPEVRFTNVPERTQID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCS 828
Query: 341 KVNCYTAFHVTCAQRAGLFMK 361
C +FHVTCA AG+ M+
Sbjct: 829 YGRCPASFHVTCAHAAGVLME 849
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 105 bits (263), Expect = 2e-22
Identities = 57/141 (40%), Positives = 82/141 (58%), Gaps = 8/141 (5%)
Query: 226 SNVILFCDICNLAVHQECYGVPY--IPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTS 283
+++++ C C + VH CYG+P I +G WLC C ++ + +C LC +GGA KQT
Sbjct: 712 TSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRN-AWTAECCLCNLRGGALKQTK 769
Query: 284 DGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICK---QKGLGAAIQCH 340
+ WAHV+CA+ +PEV F N I+ + IP R KL C C+ ++ GA IQC
Sbjct: 770 NNKWAHVMCAVAVPEVRFTNVPERTQID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCS 828
Query: 341 KVNCYTAFHVTCAQRAGLFMK 361
C +FHVTCA AG+ M+
Sbjct: 829 YGRCPASFHVTCAHAAGVLME 849
>gi|41350212 bromodomain containing 7 [Homo sapiens]
Length = 651
Score = 90.5 bits (223), Expect = 9e-18
Identities = 63/232 (27%), Positives = 118/232 (50%), Gaps = 20/232 (8%)
Query: 472 PMLAVPQIPSYRLNKICSGLS------FQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHS 525
P+ V ++ + ++ +G S F+ KN + +++ +P +
Sbjct: 22 PLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKDRKRKKRKKGEKQIPGEEKGRK 81
Query: 526 HLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQA 585
+ + + ++R++D + +++L+ +R DL + L + K+E++ EQ +Q+A
Sbjct: 82 RRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKPLTSSLAKQEEV--EQTPLQEA 139
Query: 586 AMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLES 645
N L+R LQ KDP+ F+ PV P Y I PMDFSTM+ K+++
Sbjct: 140 --------LNQLMRQ----LQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKN 187
Query: 646 HLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQA 697
+ Y+++EE +++F L+ TN M YN +TI+++AA +L G IL R Q+
Sbjct: 188 NDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQS 239
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 77.0 bits (188), Expect = 1e-13
Identities = 55/185 (29%), Positives = 85/185 (45%), Gaps = 23/185 (12%)
Query: 525 SHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKL--------- 575
S R+ +RE+ ++ K++ +K D ER + E RKRE+
Sbjct: 49 SSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEAD 108
Query: 576 -----KREQVK---------VQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLS 621
K+ +V+ + E E P LL L LQ KDP FA PV +
Sbjct: 109 DFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDA 168
Query: 622 EVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVR 681
P Y I PMDF TM+ K+ ++ Y+++ EF+ DF L+ N M YN DT++++ A +
Sbjct: 169 IAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKK 228
Query: 682 LRDLG 686
+ G
Sbjct: 229 ILHAG 233
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 73.9 bits (180), Expect = 8e-13
Identities = 40/100 (40%), Positives = 59/100 (59%), Gaps = 5/100 (5%)
Query: 226 SNVILFCDICNLAVHQECYGVPY--IPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTS 283
+++++ C C + VH CYG+P I +G WLC C ++ + +C LC +GGA KQT
Sbjct: 712 TSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRN-AWTAECCLCNLRGGALKQTK 769
Query: 284 DGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKL 323
+ WAHV+CA+ +PEV F N I+ + IP R KL
Sbjct: 770 NNKWAHVMCAVAVPEVRFTNVPERTQID-VGRIPLQRLKL 808
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 73.9 bits (180), Expect = 8e-13
Identities = 40/100 (40%), Positives = 59/100 (59%), Gaps = 5/100 (5%)
Query: 226 SNVILFCDICNLAVHQECYGVPY--IPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTS 283
+++++ C C + VH CYG+P I +G WLC C ++ + +C LC +GGA KQT
Sbjct: 734 TSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRN-AWTAECCLCNLRGGALKQTK 791
Query: 284 DGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKL 323
+ WAHV+CA+ +PEV F N I+ + IP R KL
Sbjct: 792 NNKWAHVMCAVAVPEVRFTNVPERTQID-VGRIPLQRLKL 830
>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
Length = 1458
Score = 69.3 bits (168), Expect = 2e-11
Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 588 ELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHL 647
E L + LR L +IF++PV++ EV DYLE I +PMD ST+ K++ H
Sbjct: 957 ENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHN 1016
Query: 648 YRTLEEFEEDFNLIVTNCMKYNAK----DTIFHRAAVRLRDLGGAIL 690
Y T ++F +D +LI +N ++YN D I A L+D AI+
Sbjct: 1017 YLTAKDFLKDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAII 1063
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 68.9 bits (167), Expect = 3e-11
Identities = 56/289 (19%), Positives = 123/289 (42%), Gaps = 30/289 (10%)
Query: 417 DGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAV 476
D E E EEEE++ G S K V ++ KQ +KK + DT S+
Sbjct: 1350 DDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKKITGKDIHDTASS------ 1403
Query: 477 PQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQR 536
+ GL FQR QF R + G + + ++ ++++ +R
Sbjct: 1404 ----------VARGLQFQRGLQFCTRA------SKAIEEGT--LEEIEEEVRQKKSSRKR 1445
Query: 537 EQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNV 596
++D + + + D + + +KR + E++ + ++
Sbjct: 1446 KRDSDAGSSTPTTSTRSRDKDDESKKQ------KKRGRPPAEKLSPNPPNLTKKMKKIVD 1499
Query: 597 LLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEE 656
+ D + + +F + + E+P+Y E I KP+DF ++ ++ +H YR+L + E+
Sbjct: 1500 AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEK 1559
Query: 657 DFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPE 705
D L+ N +N + ++ + ++ L+ + ++ + ++ ++ G + E
Sbjct: 1560 DVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESE 1608
Score = 31.2 bits (69), Expect = 6.2
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%)
Query: 414 KEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPS 469
KE D E EE EE EE E+E S S+K K K+ K+K ++ + G+ PS
Sbjct: 1598 KEDDSEGEESEEEEEGEEEGSESESRSVK---VKIKLGRKEK-AQDRLKGGRRRPS 1649
Score = 30.8 bits (68), Expect = 8.1
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 5/48 (10%)
Query: 419 EEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQD 466
E+E++ E EE E+E +G GS + S+K KIK +E QD
Sbjct: 1597 EKEDDSEGEESEEEEEGEEEGS-----ESESRSVKVKIKLGRKEKAQD 1639
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 67.8 bits (164), Expect = 6e-11
Identities = 39/123 (31%), Positives = 66/123 (53%), Gaps = 9/123 (7%)
Query: 573 EKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISK 632
E++KR + + + EL + NV R +D +F +PV+ EVPDY+ I +
Sbjct: 973 EEVKRLEEQEEDTFRELRIFLRNVTHRLAID-----KRFRVFTKPVDPDEVPDYVTVIKQ 1027
Query: 633 PMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAK----DTIFHRAAVRLRDLGGA 688
PMD S++ K++ H Y T++++ D +LI +N ++YN D + A LRD A
Sbjct: 1028 PMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYA 1087
Query: 689 ILR 691
I++
Sbjct: 1088 IIK 1090
>gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens]
Length = 544
Score = 65.5 bits (158), Expect = 3e-10
Identities = 30/79 (37%), Positives = 47/79 (59%)
Query: 608 KDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMK 667
+DP FA PV + P Y I PMDF TM+ K+ ++ Y+++ EF+ DF L+ N M
Sbjct: 102 RDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMT 161
Query: 668 YNAKDTIFHRAAVRLRDLG 686
YN DT++++ A ++ G
Sbjct: 162 YNRPDTVYYKLAKKILHAG 180
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 63.9 bits (154), Expect = 9e-10
Identities = 74/295 (25%), Positives = 120/295 (40%), Gaps = 45/295 (15%)
Query: 614 FAEPVNLSEVP--DYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAK 671
F +PV++ + DY + I PMD ST++ KLE+ YR +EF D L+ +NC KYN
Sbjct: 376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPP 435
Query: 672 DTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLEDFYRFSWEDVDNIL 731
D A +L+D+ +R A+ E PE SP + ++
Sbjct: 436 DHEVVAMARKLQDV--FEMRFAKMPDE-----PEEPVVAVSSPAV--------PPPTKVV 480
Query: 732 IPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLLRREINALRQKLAQPPPPQPP 791
P + + S + D S R +R+ L+ ++ A+ ++LA PQ
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDD------SEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534
Query: 792 SLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLEPTGPAPSLSEQE 851
K + + E+ ++E ++ + +K PPP + T S +
Sbjct: 535 KPKKKEKDKK--------EKKKEKHKRKEEVEENKKSKAKEPPP---KKTKKNNSSNSNV 583
Query: 852 SPPEPPTLKPINDSKPPSRF-------LKPRKVEEDELLEKSPLQLGNEPLQRLL 899
S EP +K SKPP + KP EE L +L E L R++
Sbjct: 584 SKKEPAPMK----SKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVV 634
Score = 55.8 bits (133), Expect = 2e-07
Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 2/75 (2%)
Query: 597 LLRTTLDLLQEKDPAHIFAEPVNLSEV--PDYLEFISKPMDFSTMRRKLESHLYRTLEEF 654
LLR L L + A F +PV+ ++ PDY + I PMD T++++LE++ Y +E
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQEC 125
Query: 655 EEDFNLIVTNCMKYN 669
+DFN + TNC YN
Sbjct: 126 IQDFNTMFTNCYIYN 140
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 63.9 bits (154), Expect = 9e-10
Identities = 74/295 (25%), Positives = 120/295 (40%), Gaps = 45/295 (15%)
Query: 614 FAEPVNLSEVP--DYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAK 671
F +PV++ + DY + I PMD ST++ KLE+ YR +EF D L+ +NC KYN
Sbjct: 376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPP 435
Query: 672 DTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKLEDFYRFSWEDVDNIL 731
D A +L+D+ +R A+ E PE SP + ++
Sbjct: 436 DHEVVAMARKLQDV--FEMRFAKMPDE-----PEEPVVAVSSPAV--------PPPTKVV 480
Query: 732 IPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLLRREINALRQKLAQPPPPQPP 791
P + + S + D S R +R+ L+ ++ A+ ++LA PQ
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDD------SEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534
Query: 792 SLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLEPTGPAPSLSEQE 851
K + + E+ ++E ++ + +K PPP + T S +
Sbjct: 535 KPKKKEKDKK--------EKKKEKHKRKEEVEENKKSKAKEPPP---KKTKKNNSSNSNV 583
Query: 852 SPPEPPTLKPINDSKPPSRF-------LKPRKVEEDELLEKSPLQLGNEPLQRLL 899
S EP +K SKPP + KP EE L +L E L R++
Sbjct: 584 SKKEPAPMK----SKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVV 634
Score = 55.8 bits (133), Expect = 2e-07
Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 2/75 (2%)
Query: 597 LLRTTLDLLQEKDPAHIFAEPVNLSEV--PDYLEFISKPMDFSTMRRKLESHLYRTLEEF 654
LLR L L + A F +PV+ ++ PDY + I PMD T++++LE++ Y +E
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQEC 125
Query: 655 EEDFNLIVTNCMKYN 669
+DFN + TNC YN
Sbjct: 126 IQDFNTMFTNCYIYN 140
Score = 38.5 bits (88), Expect = 0.039
Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 11/122 (9%)
Query: 782 LAQPPPPQPPSLNKTVSNGELPAGPQGDAAV---LEQALQEEPEDD--GDRDDSKLPPPP 836
L QPP QPP + + + E PA P + L+Q + +P PPPP
Sbjct: 900 LPQPPMAQPPQV--LLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957
Query: 837 TLEPTGPAPSLSEQESPPEPPTLK----PINDSKPPSRFLKPRKVEEDELLEKSPLQLGN 892
P P+ Q+ PP PP + P +PP R + + ++ +++ P G
Sbjct: 958 LPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQ 1017
Query: 893 EP 894
+P
Sbjct: 1018 QP 1019
Score = 35.4 bits (80), Expect = 0.33
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 785 PPPPQPPSLNKTVSNGELPAGPQGDAA---VLEQALQEEPEDDGDRDDSKLPPPPTLEPT 841
P P PP L + + P Q L AL ++P +R + LPP P P
Sbjct: 831 PQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRA-AALPPKPA-RPP 888
Query: 842 GPAPSLSEQESPPEPPTLKP----INDSKPPS 869
+P+L++ P+PP +P + D +PP+
Sbjct: 889 AVSPALTQTPLLPQPPMAQPPQVLLEDEEPPA 920
Score = 34.3 bits (77), Expect = 0.73
Identities = 16/42 (38%), Positives = 19/42 (45%), Gaps = 6/42 (14%)
Query: 833 PPPPTLEPTGPAPSLSEQESPPEPP------TLKPINDSKPP 868
PPPP +P P P +Q+ PP PP P S PP
Sbjct: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP 798
Score = 34.3 bits (77), Expect = 0.73
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 13/86 (15%)
Query: 780 QKLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLE 839
Q+L + PP P + V + P P ++Q LQ++P PPPP +
Sbjct: 933 QQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP-----------PPPPPPQ 981
Query: 840 PTGPAPSLSEQESPPEPPTLKPINDS 865
P P + + PP P L+P+ S
Sbjct: 982 P--QPPPQQQHQPPPRPVHLQPMQFS 1005
Score = 33.9 bits (76), Expect = 0.96
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 13/134 (9%)
Query: 777 ALRQKLAQPPPPQPPSLNKTVSNGELPAGPQG---DAAVLEQALQEEPEDDGDR----DD 829
+++Q+L Q PPP PP + + P+ +Q+ P G +
Sbjct: 965 SVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024
Query: 830 SKLPPPPTLEPTGPAPSLSEQESP----PEPPTLKPINDSKPPSRFLKPRKVEEDELLEK 885
+ PPPP +P P + SP +P + + ++ P P+ + L +
Sbjct: 1025 GQQPPPP--QPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQ 1082
Query: 886 SPLQLGNEPLQRLL 899
SP Q +P ++ L
Sbjct: 1083 SPPQQNVQPKKQEL 1096
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 63.5 bits (153), Expect = 1e-09
Identities = 34/79 (43%), Positives = 43/79 (54%)
Query: 605 LQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTN 664
++ + A F PVNL VP Y + I KPMDFST+R KL S Y LE F D L+ N
Sbjct: 2076 METHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDN 2135
Query: 665 CMKYNAKDTIFHRAAVRLR 683
C +N D+ RA +R
Sbjct: 2136 CETFNEDDSDIGRAGHNMR 2154
Score = 40.8 bits (94), Expect = 0.008
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 27/125 (21%)
Query: 147 DLDAEVEYDMDEEDLA-----WLDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLESRS 201
DL+ +E + EED+A W ++E R SA L + +L+K S
Sbjct: 1879 DLERNIERRI-EEDIAPGLRVWRRALSEAR--------SAAQVALCIQQLQK-------S 1922
Query: 202 SGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYG--VPYIPEGQWLCRCC 259
++S++ +C +C + N ++L CD C+ H C+ + IP+G W C C
Sbjct: 1923 IAWEKSIMK--VYCQICRKGD--NEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC 1978
Query: 260 LQSPS 264
+ S
Sbjct: 1979 IAKAS 1983
Score = 32.7 bits (73), Expect = 2.1
Identities = 36/163 (22%), Positives = 70/163 (42%), Gaps = 22/163 (13%)
Query: 389 PGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKS 448
PG R+ GDS + D++ +GD ++E+EE+ E+++ + +G S
Sbjct: 1286 PGRKRRRKGGDS--DYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
Query: 449 KMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWL 508
L+++I+K ++ Q S+ L + G R+ YW+
Sbjct: 1344 VEELEKQIEKLSKQQSQYRRKLFD-------ASHSLRSVMFGQDRYRR--------RYWI 1388
Query: 509 LKRQARNGVPLIRRLHSHLQSQRNAEQREQDEKTSAV--KEEL 549
L + G + + S + A++RE+ +K +V KEE+
Sbjct: 1389 L---PQCGGIFVEGMESGEGLEEIAKEREKLKKAESVQIKEEM 1428
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 62.4 bits (150), Expect = 3e-09
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Query: 567 ELIRKREKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDP-AHIFAEPVNLSEVPD 625
+L K +KL R + + + + + F+ +L + P + F PVN VPD
Sbjct: 1480 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1539
Query: 626 YLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAA 679
Y + I PMD T+R+ + H Y++ E F +D NLI+ N +KYN ++ + + A
Sbjct: 1540 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTA 1593
Score = 57.4 bits (137), Expect = 8e-08
Identities = 60/284 (21%), Positives = 115/284 (40%), Gaps = 38/284 (13%)
Query: 404 ISETGDEEGLKE-GDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEE 462
I T DEE +++ +E+ EE+ +E + Q + + + + K+K+K PE+
Sbjct: 1197 IRTTKDEEFIRKFALFDEQHREEMRKERRRIQ-------EQLRRLKRNQEKEKLKGPPEK 1249
Query: 463 AGQDTPSTLPMLAVPQIPSYRLN-KICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIR 521
+ + + P +L C + R N+F Y+ N V +
Sbjct: 1250 KPKK---------MKERPDLKLKCGACGAIGHMRTNKFCPL---YYQTNAPPSNPVAMTE 1297
Query: 522 RLHSHLQSQRNAEQREQDEKTSAVKEEL-KYWQKLRHDLERARLLIELIRKR-------- 572
L+ E+ K K L K + ++ R L+++ +++
Sbjct: 1298 EQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRR 1357
Query: 573 -------EKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPD 625
+ L R + + + ++ + +L + ++ +++ + F PVN V D
Sbjct: 1358 VGTTVHCDYLNRPHKSIHRRRTD-PMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKD 1416
Query: 626 YLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYN 669
Y + I++PMD T+R + LY + EEF E LIV N YN
Sbjct: 1417 YYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYN 1460
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,560,608
Number of Sequences: 37866
Number of extensions: 3164187
Number of successful extensions: 32024
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 393
Number of HSP's successfully gapped in prelim test: 828
Number of HSP's that attempted gapping in prelim test: 19696
Number of HSP's gapped (non-prelim): 8822
length of query: 1205
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1091
effective length of database: 13,930,794
effective search space: 15198496254
effective search space used: 15198496254
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.