Search of human proteins with 148727333

Search of human proteins with 148727333

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148727333 adenylate kinase 7 [Homo sapiens]
         (723 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148727333 adenylate kinase 7 [Homo sapiens]                       1435   0.0  
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom...    64   4e-10
gi|14211889 dpy-30-like protein [Homo sapiens]                         54   4e-07
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    53   9e-07
gi|4505413 non-metastatic cells 5, protein expressed in (nucleos...    52   3e-06
gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]                 48   4e-05
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]                 48   4e-05
gi|148746195 trichohyalin [Homo sapiens]                               45   3e-04
gi|4506467 radixin [Homo sapiens]                                      43   0.001
gi|45446749 kinesin family member 5A [Homo sapiens]                    43   0.001
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap...    42   0.003
gi|44890052 stathmin 1 isoform a [Homo sapiens]                        41   0.003
gi|44890050 stathmin 1 isoform a [Homo sapiens]                        41   0.003
gi|5031851 stathmin 1 isoform a [Homo sapiens]                         41   0.003
gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo sa...    41   0.003
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            41   0.003
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            40   0.006
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    40   0.006
gi|13027602 DDRGK domain containing 1 [Homo sapiens]                   40   0.008
gi|14269586 mitochondrial ribosomal protein S26 [Homo sapiens]         40   0.008
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]         40   0.010
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    40   0.010
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    39   0.013
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                39   0.017
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                39   0.017
gi|45439327 periplakin [Homo sapiens]                                  39   0.017
gi|24308223 hypothetical protein LOC57577 [Homo sapiens]               39   0.017
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    39   0.022
gi|56549694 enabled homolog isoform a [Homo sapiens]                   39   0.022
gi|39930375 enabled homolog isoform b [Homo sapiens]                   39   0.022

>gi|148727333 adenylate kinase 7 [Homo sapiens]
          Length = 723

 Score = 1435 bits (3715), Expect = 0.0
 Identities = 723/723 (100%), Positives = 723/723 (100%)

Query: 1   MAEEEETAALTEKVIRTQRVFINLLDSYSSGNIGKFLSNCVVGASLEEITEEEEEEDENK 60
           MAEEEETAALTEKVIRTQRVFINLLDSYSSGNIGKFLSNCVVGASLEEITEEEEEEDENK
Sbjct: 1   MAEEEETAALTEKVIRTQRVFINLLDSYSSGNIGKFLSNCVVGASLEEITEEEEEEDENK 60

Query: 61  SAMLEASSTKVKEGTFQIVGTLSKPDSPRPDFAVETYSAISREDLLMRLLECDVIIYNIT 120
           SAMLEASSTKVKEGTFQIVGTLSKPDSPRPDFAVETYSAISREDLLMRLLECDVIIYNIT
Sbjct: 61  SAMLEASSTKVKEGTFQIVGTLSKPDSPRPDFAVETYSAISREDLLMRLLECDVIIYNIT 120

Query: 121 ESSQQMEEAIWAVSALSEEVSHFEKRKLFILLSTVMTWARSKALDPEDSEVPFTEEDYRR 180
           ESSQQMEEAIWAVSALSEEVSHFEKRKLFILLSTVMTWARSKALDPEDSEVPFTEEDYRR
Sbjct: 121 ESSQQMEEAIWAVSALSEEVSHFEKRKLFILLSTVMTWARSKALDPEDSEVPFTEEDYRR 180

Query: 181 RKSHPNFLDHINAEKMVLKFGKKARKFAAYVVAAGLQYGAEGGMLHTFFKMAWLGEIPAL 240
           RKSHPNFLDHINAEKMVLKFGKKARKFAAYVVAAGLQYGAEGGMLHTFFKMAWLGEIPAL
Sbjct: 181 RKSHPNFLDHINAEKMVLKFGKKARKFAAYVVAAGLQYGAEGGMLHTFFKMAWLGEIPAL 240

Query: 241 PVFGDGTNVIPTIHVLDLAGVIQNVIDHVPKPHYLVAVDESVHTLEDIVKCISKNTGPGK 300
           PVFGDGTNVIPTIHVLDLAGVIQNVIDHVPKPHYLVAVDESVHTLEDIVKCISKNTGPGK
Sbjct: 241 PVFGDGTNVIPTIHVLDLAGVIQNVIDHVPKPHYLVAVDESVHTLEDIVKCISKNTGPGK 300

Query: 301 IQKIPRENAYLTKDLTQDCLDHLLVNLRMEALFVKENFNIRWAAQTGFVENINTILKEYK 360
           IQKIPRENAYLTKDLTQDCLDHLLVNLRMEALFVKENFNIRWAAQTGFVENINTILKEYK
Sbjct: 301 IQKIPRENAYLTKDLTQDCLDHLLVNLRMEALFVKENFNIRWAAQTGFVENINTILKEYK 360

Query: 361 QSRGLMPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGE 420
           QSRGLMPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGE
Sbjct: 361 QSRGLMPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGE 420

Query: 421 GEEEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYIL 480
           GEEEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYIL
Sbjct: 421 GEEEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYIL 480

Query: 481 DGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPE 540
           DGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPE
Sbjct: 481 DGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPE 540

Query: 541 SIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQ 600
           SIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQ
Sbjct: 541 SIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQ 600

Query: 601 LIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNK 660
           LIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNK
Sbjct: 601 LIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNK 660

Query: 661 RLEEVKREERELLEAQSIPLRNYLMTYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKNNP 720
           RLEEVKREERELLEAQSIPLRNYLMTYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKNNP
Sbjct: 661 RLEEVKREERELLEAQSIPLRNYLMTYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKNNP 720

Query: 721 EAQ 723
           EAQ
Sbjct: 721 EAQ 723


>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 1911

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 77/335 (22%), Positives = 132/335 (39%), Gaps = 88/335 (26%)

Query: 367  PIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISE-AIAKLEAIVAPNDVGEGEEE- 424
            P++IC++GP   GK+   ++LA    + HIQ ++V+ E  + K E  V P    + E E 
Sbjct: 991  PLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQ 1050

Query: 425  ----------------VEEEEEEENVEDAQ--ELLDGIKESMEQNAGQLDDQYIIRFMKE 466
                            VEEE  ++ + + Q  E  + IK S+ +N   L  + +   + E
Sbjct: 1051 AAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENE-PLPPEILEVILSE 1109

Query: 467  KLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDA 526
                 P R+ G+ILDGFP+  ++A+                  F  D+   P+    +  
Sbjct: 1110 WWLKEPIRSTGFILDGFPRYPEEAQ------------------FLGDRGFFPDAAVFIQV 1151

Query: 527  SDEFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDV 586
             D+ + +R++                                            P  I+ 
Sbjct: 1152 DDQDIFDRLL--------------------------------------------PAQIEK 1167

Query: 587  GKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAE---EERKAAEERLAREAAEEAEREHQ 643
             KL+  + +L  K+LIK++          + +AE   E  K   E + R+  E +E E +
Sbjct: 1168 WKLKQ-KKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEELE 1226

Query: 644  EAVEMAEKIARWEEWNKRLEEVKREERELLEAQSI 678
            E  +  E I   +E+ K  EE+  EE E  E  +I
Sbjct: 1227 EDNDDIENILE-DEFPKDEEEMSGEEDEEQETDAI 1260



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 62/304 (20%), Positives = 111/304 (36%), Gaps = 77/304 (25%)

Query: 367 PIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVE 426
           P+   + G P VGK+++A+ +   +K   ++   ++ E IA                   
Sbjct: 30  PVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIA------------------- 70

Query: 427 EEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKT 486
             E E  V         + +SM  +   + D+ +I+ M EKL S    + GYI+   P  
Sbjct: 71  -AETESGV---------MLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120

Query: 487 YDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPESIVAGT 546
              A     Q +  +  +++           P+ +  +   D  L +R+    +    G 
Sbjct: 121 SQDAMTTLQQIELIKNLNLK-----------PDVIINIKCPDYDLCQRISGQRQHNNTGY 169

Query: 547 HYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIG 606
            YS+D++            D E + N+              K ++AQ            G
Sbjct: 170 IYSRDQW------------DPEVIENHRK------------KKKEAQK--------DGKG 197

Query: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARW--EEWNKRLEE 664
           E       +EE+ EEE   AE ++  E      +  ++ +E  E I +   E   + LEE
Sbjct: 198 EEEE---EEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEE 254

Query: 665 VKRE 668
           V  E
Sbjct: 255 VMAE 258



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 27/124 (21%)

Query: 366  MPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEV 425
            +PI+I I+GPP  GK+++AK++ + Y L H+ +   +   +                   
Sbjct: 1410 VPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVL------------------- 1450

Query: 426  EEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPK 485
                     E A  L   + + M        D+  I+ ++  L    C   G ++DG+P 
Sbjct: 1451 ---NNHPETELALMLNWHLHKGM-----TAPDELAIQALELSLMESVCNTAGVVIDGYPV 1502

Query: 486  TYDQ 489
            T  Q
Sbjct: 1503 TKHQ 1506



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 17/72 (23%), Positives = 31/72 (43%)

Query: 367 PIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVE 426
           P K+ ILGP   GK+++   LA  YK   +    ++     K    +  N + E      
Sbjct: 391 PCKVFILGPQYSGKTTLCNMLAENYKGKVVDYAQLVQPRFDKARETLVENTIAEATAAAI 450

Query: 427 EEEEEENVEDAQ 438
           +  +E+ + + Q
Sbjct: 451 KVVKEKLLRELQ 462


>gi|14211889 dpy-30-like protein [Homo sapiens]
          Length = 99

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 7/96 (7%)

Query: 628 ERLAREAAEEAEREHQE--AVEMAEKIARWEEWNKRLEEVKREERELLEAQSIPLRNYLM 685
           E++     + AE  H E    +  E+I   E+ N      ++  ++ ++ QS+P R YL 
Sbjct: 4   EQMLEGQTQVAENPHSEYGLTDNVERIVENEKIN-----AEKSSKQKVDLQSLPTRAYLD 58

Query: 686 TYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKNNPE 721
             V+P L+QGL      RP +P++FLA YL KN  +
Sbjct: 59  QTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQ 94


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 76/340 (22%), Positives = 148/340 (43%), Gaps = 82/340 (24%)

Query: 382 SIAKELANYYKLHH--IQLKDVISEAIAKLEAIVAPNDVGEGEEEVEEEEEE-ENVEDAQ 438
           ++   L N  K H   +  +  I E   +LE++    ++   +EE+E+ E E + V  A+
Sbjct: 553 AVTAYLKNSRKEHQRILARRQTIEERKERLESL----NIQREKEELEQREAELQKVRKAE 608

Query: 439 ELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQED 498
           E      E + Q A + + + I++   E++K    R +   L+   KT   AK   + + 
Sbjct: 609 E------ERLRQEAKEREKERILQ-EHEQIKKKTVRER---LEQIKKTELGAKAFKDIDI 658

Query: 499 EEEEDDVRGRMFPFDKLIIPEFVCA-----LDASDEFLKERVINLPESIVAGTHYSQDRF 553
           E+ E+            + P+F+ A     L+   + L+ER+ N  + I    ++ + + 
Sbjct: 659 EDLEE------------LDPDFIMAKQVEQLEKEKKELQERLKNQEKKI---DYFERAKR 703

Query: 554 LRAL----SNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLA------------ 597
           L  +    S Y +  I D  ++   +E  I  + ++  K  + +NR++            
Sbjct: 704 LEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMR 763

Query: 598 ------------IKQLIKEIGEPRNYGLTDE--------------EKAEEERKAAEERLA 631
                       +KQ  + + E R+  L +               EK EEE++ AEE++ 
Sbjct: 764 LKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQML 823

Query: 632 REAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERE 671
           +   E  ERE  E  +  E++  ++E  K+LEEV+R++R+
Sbjct: 824 K---EREERERAERAKREEELREYQERVKKLEEVERKKRQ 860


>gi|4505413 non-metastatic cells 5, protein expressed in
           (nucleoside-diphosphate kinase) [Homo sapiens]
          Length = 212

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 20/40 (50%), Positives = 31/40 (77%)

Query: 681 RNYLMTYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKNNP 720
           ++YL  ++MPTL++GL E C  +P DP+ +LA++L KNNP
Sbjct: 158 KDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNP 197


>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
          Length = 239

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 32/136 (23%)

Query: 368 IKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEE 427
           I+  +LGPP  GK + A  LA  + + H+   D++   +A                    
Sbjct: 16  IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVAS------------------- 56

Query: 428 EEEEENVEDAQELLDGIKESMEQNAGQL-DDQYIIRFMKEKLKSMPCRNQGYILDGFPKT 486
                      EL   +K +M+  AG+L  D+ ++  +++ L++  C+N G++LDGFP+T
Sbjct: 57  ---------GSELGKKLKATMD--AGKLVSDEMVVELIEKNLETPLCKN-GFLLDGFPRT 104

Query: 487 YDQAKDLFNQEDEEEE 502
             QA+ L +  ++ +E
Sbjct: 105 VRQAEMLDDLMEKRKE 120


>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
          Length = 232

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 32/136 (23%)

Query: 368 IKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEE 427
           I+  +LGPP  GK + A  LA  + + H+   D++   +A                    
Sbjct: 16  IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVAS------------------- 56

Query: 428 EEEEENVEDAQELLDGIKESMEQNAGQL-DDQYIIRFMKEKLKSMPCRNQGYILDGFPKT 486
                      EL   +K +M+  AG+L  D+ ++  +++ L++  C+N G++LDGFP+T
Sbjct: 57  ---------GSELGKKLKATMD--AGKLVSDEMVVELIEKNLETPLCKN-GFLLDGFPRT 104

Query: 487 YDQAKDLFNQEDEEEE 502
             QA+ L +  ++ +E
Sbjct: 105 VRQAEMLDDLMEKRKE 120


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 66/306 (21%), Positives = 130/306 (42%), Gaps = 38/306 (12%)

Query: 394  HHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEEEEEEENVEDAQELLDGIKESMEQNAG 453
            H +  K  + E + K + ++      E EEE++ EE E+     QE     ++  E+   
Sbjct: 887  HTLYAKPALQEQLRKEQQLLQ-----EEEEELQREEREKRRRQEQE-----RQYREEEQL 936

Query: 454  QLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFD 513
            Q +++ ++R  +EK +    R + Y  D   K   + + L  +E E+     R + +  +
Sbjct: 937  QQEEEQLLREEREKRRRQE-RERQYRKD--KKLQQKEEQLLGEEPEKRRRQEREKKYREE 993

Query: 514  KLIIPEFVCALDASDEFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNY 573
            + +  E    L    E  + +               +++ LR     R +  + E  +  
Sbjct: 994  EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ-ERERQYRE 1052

Query: 574  FDELEIHPIHIDVGKLEDAQNRLAIK--------------QLIKEIGEPRNYGLTDEE-K 618
             +EL+     + +G+  + + R  ++              QL++E  E R     + + +
Sbjct: 1053 EEELQQEEEQL-LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111

Query: 619  AEEERKAAEERLAREAAE-----EAEREHQEAVEM---AEKIARWEEWNKRLEEVKREER 670
             EEE +  EE+L RE  E     E ER+++E  E+    E++ R E   +R +E++R+ R
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171

Query: 671  ELLEAQ 676
            E  E Q
Sbjct: 1172 EEEELQ 1177



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 4/72 (5%)

Query: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAE-EAEREHQEAVEMAEKIARWEE-WNKRLEE 664
           EPR+  L  EE+  + R+   +   RE AE E + E QE +E  ++  R EE W +R E 
Sbjct: 123 EPRDRQL--EEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW 180

Query: 665 VKREERELLEAQ 676
            +REER   E Q
Sbjct: 181 QEREERRAEEEQ 192



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 16/57 (28%), Positives = 34/57 (59%)

Query: 615 DEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERE 671
           +E + + E +  EE+L +   +E  RE QE  +  +++ R ++  ++ EE +RE++E
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 1/88 (1%)

Query: 590 EDAQNRL-AIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEM 648
           E  Q RL + +QL +E  E R   L  EE+   E++  E+RL RE  E  ++  +   E 
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585

Query: 649 AEKIARWEEWNKRLEEVKREERELLEAQ 676
            ++  + E+  +  + +KREE E LE +
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQE 613



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 10/87 (11%)

Query: 599  KQLIKEIGEPRN-YGLTDEEKAEEERKAAEERLAREAAE-----EAEREHQEAVEM---A 649
            +QL++E  E R    L  + + EEE +  EE+L RE  E     E ER+++E  E+    
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180

Query: 650  EKIARWEEWNKRLEEVKREERELLEAQ 676
            E++ R EE  KR +E +R+ RE  E Q
Sbjct: 1181 EQLLR-EEQEKRRQERERQYREEEELQ 1206



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 20/91 (21%)

Query: 599 KQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAE---------EAEREHQEA---- 645
           +QL +E  E R+     E+K E+ER+  E+RL RE  E         E ER  QE     
Sbjct: 423 QQLRREQEEERH-----EQKHEQERR--EQRLKREQEERRDWLKREEETERHEQERRKQQ 475

Query: 646 VEMAEKIARWEEWNKRLEEVKREERELLEAQ 676
           ++  ++  R E W K  EE +RE++E  E Q
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQ 506



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 63/262 (24%), Positives = 106/262 (40%), Gaps = 32/262 (12%)

Query: 422  EEEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILD 481
            E E +  EEEE  ++ ++LL   +E  E+   + + QY     +E+      R Q Y   
Sbjct: 1165 ELERQYREEEELQQEEEQLL---REEQEKRRQERERQY----REEEELQRQKRKQRY--- 1214

Query: 482  GFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPES 541
               +  DQ  DL  Q + E+E+ VR            +F       D  L++R       
Sbjct: 1215 ---RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF---RQLEDSQLRDRQSQQDLQ 1268

Query: 542  IVAGTHYSQDRFL-RALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQ 600
             + G    +DR   R     RD +  +E      ++ E         K  D +++   KQ
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE--------AKRRDRKSQEE-KQ 1319

Query: 601  LIKEIGEPRNYGLTDEEKAEEERKAAEER----LAREAAEEAEREHQEAVEMAEKIARWE 656
            L++E  E +      + K  EE +  +ER    L R+  +   RE  E +   E+  ++ 
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE--EELRHQEQGRKFL 1377

Query: 657  EWNKRLEEVKREERELLEAQSI 678
            E  +RL   +RE + L E Q +
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQL 1399



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMA 649
           ++ + R A ++ ++           DEE+          R  RE  ++  RE Q+ V   
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240

Query: 650 EKIARWEEWNKRLEEVKREERELLEAQ 676
           E+    +EW KR   +++EE +L E +
Sbjct: 241 EEE---KEWRKRETVLRKEEEKLQEEE 264



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 8/70 (11%)

Query: 615 DEEKAEEERKAAEERLAREAAEEAER-----EHQEAVEM---AEKIARWEEWNKRLEEVK 666
           +EE+  E+++  E++L RE  E  E+     E +E ++    +E+  R E+  +R + +K
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551

Query: 667 REERELLEAQ 676
           REE + LE +
Sbjct: 552 REEEKRLEQE 561



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEE--RKAAEERLAREAAEEAEREHQEAVE 647
           E  Q RL  +Q ++   E        EE+ E++  R+  EER  ++   E E   ++ + 
Sbjct: 294 EQQQQRLRREQQLRRKQEEERRE-QQEERREQQERREQQEERREQQLRREQEERREQQLR 352

Query: 648 MAEKIARWEEWNKRLEEVKREERELLEAQSI 678
             ++  R E+  +R +E +R E++L   Q +
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQL 383



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 60/271 (22%), Positives = 105/271 (38%), Gaps = 44/271 (16%)

Query: 423  EEVEEEEEEENVEDAQELLDGIKESMEQNAGQ---LDDQYIIRFMKEKLKSMPCRNQGYI 479
            EE E+ +  E  +  QE  DG++E  E+   Q    D ++  +  +E+ +    R+  Y 
Sbjct: 835  EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR---RHTLYA 891

Query: 480  LDGFPKTYDQAKDLFNQEDEE---EEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVI 536
                 +   + + L  +E+EE   EE + R R                +   ++ +E  +
Sbjct: 892  KPALQEQLRKEQQLLQEEEEELQREEREKRRRQ---------------EQERQYREEEQL 936

Query: 537  NLPESIVAGTHYSQDRFLRALSNYR-DINIDDETVFNYFDELEIHPIHIDVGKL-EDAQN 594
               E  +      + R       YR D  +  +      +E E         K  E+ + 
Sbjct: 937  QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996

Query: 595  RLAIKQLIKEIGEPRN-------YGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVE 647
            +   +QL++E  E R        Y   DE + EEE+   EER  R   +E ER+++E   
Sbjct: 997  QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL-QERERQYREE-- 1053

Query: 648  MAEKIARWEEWNKRLEEVKREERELLEAQSI 678
                    EE  +  E++  EERE    Q +
Sbjct: 1054 --------EELQQEEEQLLGEERETRRRQEL 1076



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/72 (27%), Positives = 33/72 (45%)

Query: 603 KEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRL 662
           +E+ E        E   + +R+  +E L R+  E  ERE + A E   +  +  E  +  
Sbjct: 146 RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205

Query: 663 EEVKREERELLE 674
           +E +   RELLE
Sbjct: 206 DEEQLRRRELLE 217



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 6/83 (7%)

Query: 588 KLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVE 647
           KLE+ + R   ++  +++   +        K +EE +  ++RL  E     E+E     E
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE-----E 544

Query: 648 MAEKIARWEEWNKRLEEVKREER 670
             E++ + EE  KRLE+ +RE+R
Sbjct: 545 RREQLLKREE-EKRLEQERREQR 566



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 599  KQLIKEIGEPRN-YGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEE 657
            +QL++E  E R    L  + + EEE +  EE+L RE  E+  +E +      E++ R + 
Sbjct: 1151 EQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210

Query: 658  WNKRLEEVKREE 669
              +  +E +R +
Sbjct: 1211 KQRYRDEDQRSD 1222



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 599 KQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEW 658
           +Q +K   E R   L  EE+ E      +ER  ++   + E E +E     E+  R E+ 
Sbjct: 444 EQRLKREQEERRDWLKREEETERHE---QERRKQQLKRDQEEERRERWLKLEEEERREQQ 500

Query: 659 NKRLEEVKREERELLE 674
            +R ++++RE+ E  E
Sbjct: 501 ERREQQLRREQEERRE 516



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 616 EEKAEEE--RKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERELL 673
           EE+ E++  R+  EER  ++   E E E +E     E+  R E+  +R ++++RE++   
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403

Query: 674 EAQ 676
           E Q
Sbjct: 404 EQQ 406



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 5/80 (6%)

Query: 600 QLIKEIGEPRNYGLT--DEEKAEEERKAAE-ERLAREAAEEA--EREHQEAVEMAEKIAR 654
           QL+K   E R   L    EE+ E+  K  E ERL +E   E   +RE  E     + +  
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636

Query: 655 WEEWNKRLEEVKREERELLE 674
            E+  +R ++++RE++E  E
Sbjct: 637 EEQEERRQQQLRREQQERRE 656



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 9/88 (10%)

Query: 588 KLEDAQNRLAIKQLIKEIGEPRNYGLT---DEEKAEE--ERKAAEERLAREAAEEAEREH 642
           K E+ + R   +QL +E  E R   L    +EE+ E+  +R+  EER  +E AEE + + 
Sbjct: 635 KSEEQEERRQ-QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693

Query: 643 QEAVEMAEKIARWEEWNKRLEEVKREER 670
           +E ++   +I +W +W    E   R+ +
Sbjct: 694 RERIK--SRIPKW-QWQLESEADARQSK 718


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/71 (38%), Positives = 42/71 (59%), Gaps = 6/71 (8%)

Query: 604 EIGEPRNYGLTDEEKAEEERKAAEE---RLAREAAEEAEREHQEAVEMAE---KIARWEE 657
           E+ + R     + E+ E+ER+AAEE    +A++AA++ + + Q A E+AE   KIA  EE
Sbjct: 374 ELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEE 433

Query: 658 WNKRLEEVKRE 668
             K+ EE   E
Sbjct: 434 AKKKKEEEATE 444



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 20/79 (25%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 596 LAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARW 655
           + ++Q+  +  E ++    +  + E E+K  E  +A +  E  ERE +E +E  ++I   
Sbjct: 300 IEVQQMKAQAREEKHQKQLERAQLENEKKKRE--IAEKEKERIEREKEELMERLKQIE-- 355

Query: 656 EEWNKRLEEVKREERELLE 674
           E+  K  +E++ + R+ LE
Sbjct: 356 EQTIKAQKELEEQTRKALE 374


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 68/290 (23%), Positives = 124/290 (42%), Gaps = 51/290 (17%)

Query: 392 KLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEEEEEEENVEDAQELLDGIKESMEQN 451
           K H  +  D +S+ +AKL+A        E   EV  +++E + +DA E+   ++  ME +
Sbjct: 654 KRHLEESYDSLSDELAKLQA-------QETVHEVALKDKEPDTQDADEVKKALELQMESH 706

Query: 452 AGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFP 511
             +   + + R   E             ++   KT D+ KDL NQ+ + E + ++     
Sbjct: 707 R-EAHHRQLARLRDE-------------INEKQKTIDELKDL-NQKLQLELEKLQA---D 748

Query: 512 FDKLIIPEFVCALDASD-EFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETV 570
           ++KL   E   +    +  FL ER     + +  G   +  R L+ L N R + + D T 
Sbjct: 749 YEKLKSEEHEKSTKLQELTFLYERHEQSKQDL-KGLEETVARELQTLHNLRKLFVQDVTT 807

Query: 571 FNYFDELEIHP-----IHIDVGKLEDAQNRL-----AIKQLIKEIGEPRNYGLTDEEKAE 620
                  E+ P     IH    K+   +N L       KQL+++  + R     +  K E
Sbjct: 808 -RVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLR----CELPKLE 862

Query: 621 EERKAAEERL---------AREAAEEAEREHQEAVEMAEKIARWEEWNKR 661
           +  +A  ER+         A+E A + +R +Q+ V+  ++  R++   KR
Sbjct: 863 KRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKR 912


>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo
           sapiens]
          Length = 1503

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 55/224 (24%), Positives = 90/224 (40%), Gaps = 56/224 (25%)

Query: 532 KERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDET---VFNYFDELEIHPIHID--- 585
           KER  NL E  V   H         L +  D+ + ++T   V    DE++   ++++   
Sbjct: 21  KERKWNLTE--VKELH-------ETLQSVPDVPVKEDTNSVVEKAMDEIKSQELNLEGQR 71

Query: 586 ---VGKLED----AQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEA 638
               G ++D    A   +AI++  K I     + L + E   +     ++ L        
Sbjct: 72  KISPGSIKDSKTEASGNIAIRKSAKVI-----FALDETELKSKPEHTWKKNLF------- 119

Query: 639 EREHQEAVEMAEKIARWEEWNKRLEEVKREE-------RELLEAQSIPLRN--YLMTYVM 689
           ER    A  M +KI   E   K LE+   ++       +E     S+ L N  YL+  ++
Sbjct: 120 ERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLDKLL 179

Query: 690 PTLIQG-------------LNECCNVRPEDPVDFLAEYLFKNNP 720
           PTL+ G             L E       DP+++L EYL +NNP
Sbjct: 180 PTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNP 223


>gi|44890052 stathmin 1 isoform a [Homo sapiens]
          Length = 149

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 9/88 (10%)

Query: 588 KLEDAQNRLAIKQ--LIKEIGEPRNYGLTDEEKAEEER----KAAEERLAREAAEEAERE 641
           KLE A+ R    +  ++K++ E R +     +KA EE     K AEE+L  +   EA +E
Sbjct: 53  KLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKM--EANKE 110

Query: 642 HQEAVEMAEKIARWEEWNKRLEEVKREE 669
           ++EA +MA K+ R  E +K +EEV++ +
Sbjct: 111 NREA-QMAAKLERLREKDKHIEEVRKNK 137


>gi|44890050 stathmin 1 isoform a [Homo sapiens]
          Length = 149

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 9/88 (10%)

Query: 588 KLEDAQNRLAIKQ--LIKEIGEPRNYGLTDEEKAEEER----KAAEERLAREAAEEAERE 641
           KLE A+ R    +  ++K++ E R +     +KA EE     K AEE+L  +   EA +E
Sbjct: 53  KLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKM--EANKE 110

Query: 642 HQEAVEMAEKIARWEEWNKRLEEVKREE 669
           ++EA +MA K+ R  E +K +EEV++ +
Sbjct: 111 NREA-QMAAKLERLREKDKHIEEVRKNK 137


>gi|5031851 stathmin 1 isoform a [Homo sapiens]
          Length = 149

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 9/88 (10%)

Query: 588 KLEDAQNRLAIKQ--LIKEIGEPRNYGLTDEEKAEEER----KAAEERLAREAAEEAERE 641
           KLE A+ R    +  ++K++ E R +     +KA EE     K AEE+L  +   EA +E
Sbjct: 53  KLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKM--EANKE 110

Query: 642 HQEAVEMAEKIARWEEWNKRLEEVKREE 669
           ++EA +MA K+ R  E +K +EEV++ +
Sbjct: 111 NREA-QMAAKLERLREKDKHIEEVRKNK 137


>gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo
           sapiens]
          Length = 856

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 22/104 (21%)

Query: 639 EREHQEAVEMAEKIARWEEWNKRLEEVKREE-------RELLEAQSIPLRN--YLMTYVM 689
           ER    A  M +KI   E   K LE+   ++       +E     S+ L N  YL+  ++
Sbjct: 64  ERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLDKLL 123

Query: 690 PTLIQG-------------LNECCNVRPEDPVDFLAEYLFKNNP 720
           PTL+ G             L E       DP+++L EYL +NNP
Sbjct: 124 PTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNP 167


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 12/101 (11%)

Query: 588 KLEDA-QNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERL------AREAAEEAER 640
           +LE A Q R A+ + +   G  R     +  +   + +AAEER+       R+  EEAER
Sbjct: 803 ELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERMQVLESEGRQHLEEAER 862

Query: 641 EHQE----AVEMAEKIARWEEWNKRLEEVKRE-ERELLEAQ 676
           E +E      E+ + + R +E   RLE ++RE E+  LE Q
Sbjct: 863 ERREKEALQAELEKAVVRGKELGARLEHLQRELEQAALERQ 903


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 592 AQNRLAIKQLIKEIGEP--RNYGL-TDEEKAEEERKAAEERLAREAAEEAEREHQEAVEM 648
           A NRL++ +    + E      GL  +EE+ EEE +  EE    E  EE E E ++  E 
Sbjct: 93  AGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK 152

Query: 649 AEKIARWEEWNKRLEEVKREERELLEAQ 676
            E     E+  K++EE K EE    E Q
Sbjct: 153 EEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 401 VISEAIAKLEAIVAPNDVGEGEEEVEEEEEEENVEDAQE 439
           V  E  A+    V   +V E EEEVEEEE+EE  E+ +E
Sbjct: 106 VAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEE 144


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%)

Query: 615 DEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREER-ELL 673
           ++EK +EE K A+E   ++  EE E + +E  E  EK  + +   +RL+E +R+ER E L
Sbjct: 356 EKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEAL 415

Query: 674 EAQ 676
           EA+
Sbjct: 416 EAK 418



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 612 GLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERE 671
           G T++ K   +R   +ERL ++    AERE +E ++   K A+ E   K+ EE + +E+E
Sbjct: 328 GSTEKNKLRLQRD--QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKE 385

Query: 672 LLE 674
             E
Sbjct: 386 RRE 388



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMA 649
           E+A+ +   ++ +KE          ++EKAE++R   E R  R+ A EA+ E +   E  
Sbjct: 369 EEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKE-E 427

Query: 650 EKIARWEEWNKRLEEVKREERELLEAQSIP 679
           EK  R EE  KR++  K E     +    P
Sbjct: 428 EKRLREEE--KRIKAEKAEITRFFQKPKTP 455



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 595 RLAIKQLIKEIGEPRNYGLT-DEEKAEEERKAAEERLAREAA-EEAEREHQEAVEMAEKI 652
           R   K+ +K   E     L  D+E+  ++ K   ER  +E   EEA+R  +EA +  E+ 
Sbjct: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378

Query: 653 ARWEEWNKRLEEVKREERELLEAQSI 678
              +E  +R E+ +++E+E  E Q +
Sbjct: 379 KELKE-KERREKREKDEKEKAEKQRL 403


>gi|13027602 DDRGK domain containing 1 [Homo sapiens]
          Length = 314

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 5/86 (5%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEE--RLAREAAEEAEREHQEAVE 647
           E+ +  + + Q  + + +P    L+ +  A++ RK  E+  R A+  AEEAERE ++ +E
Sbjct: 90  ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLE 149

Query: 648 MAEKIARW--EEWNKRLEEVKREERE 671
            +++ A W  EE   RLEE ++EE E
Sbjct: 150 -SQREAEWKKEEERLRLEEEQKEEEE 174



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 8/51 (15%)

Query: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEE 657
           E     L +E+K EEERKA E        E+A+REH+E +++ E     EE
Sbjct: 159 EEERLRLEEEQKEEEERKARE--------EQAQREHEEYLKLKEAFVVEEE 201



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAE----ERLAREAAEEAE-REHQE 644
           E+   + A   L  +IG  +   L +++  + +R+A E    ER   E+  EAE ++ +E
Sbjct: 102 EEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEE 161

Query: 645 AVEMAEKIARWEEWNKRLEEVKREERELLE 674
            + + E+    EE   R E+ +RE  E L+
Sbjct: 162 RLRLEEEQKEEEERKAREEQAQREHEEYLK 191



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 25/95 (26%)

Query: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAE---------------- 650
           EPR  G     +    R  A+ R  R A  EA+   +EAV +A+                
Sbjct: 57  EPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGK 116

Query: 651 ----KIARWEEWNKR-----LEEVKREERELLEAQ 676
               K+ + EE   R      EE +REER+ LE+Q
Sbjct: 117 IGAKKLRKLEEKQARKAQREAEEAEREERKRLESQ 151


>gi|14269586 mitochondrial ribosomal protein S26 [Homo sapiens]
          Length = 205

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 10/89 (11%)

Query: 596 LAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARW 655
           LA ++ +K+  E R     ++    E R+  E R+AR   EE E+E ++A+E A K    
Sbjct: 90  LAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQEQRQALEQARKAEEV 146

Query: 656 EEWNKRLEEVKREERELLEAQSIPLRNYL 684
           + W       +R+ERE+L+ Q   ++N++
Sbjct: 147 QAW------AQRKEREVLQLQE-EVKNFI 168


>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
          Length = 439

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 55/243 (22%), Positives = 104/243 (42%), Gaps = 30/243 (12%)

Query: 397 QLKDVISEAIAKLEAIVAPNDVGEGEEEVEEE----EEEENVEDAQELLDGIKESMEQNA 452
           ++ + + E +A+   IV P  VGE + EVE +    E E++ E+ +E +D   E +E+  
Sbjct: 92  RISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEID--DEEIERRR 149

Query: 453 GQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPF 512
           G +  +   R   E+++ M   ++G          +   +   +E  + ED++  R+ P 
Sbjct: 150 GMMRQRAQER-KNEEMEVMEVEDEG------RSGEESESESEYEEYTDSEDEMEPRLKPV 202

Query: 513 -----DKLIIPEFVCAL-------DASDEFLKERVINLPESIVAGTHYSQDRFLRALSNY 560
                D++ + E              +    +ER     + +   T    +   R+L+  
Sbjct: 203 FIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAAL 262

Query: 561 RDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAE 620
             +N DDE   N  +E E   +        D ++R A+++   EI   RN  LT+EE+  
Sbjct: 263 DALNTDDE---NDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRN--LTEEERRA 317

Query: 621 EER 623
           E R
Sbjct: 318 ELR 320



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 11/87 (12%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMA 649
           ED + RLA     ++I EP   G +D E         E    R   E++  E +E ++  
Sbjct: 95  EDVEERLARH---RKIVEPEVVGESDSE--------VEGDAWRMEREDSSEEEEEEIDDE 143

Query: 650 EKIARWEEWNKRLEEVKREERELLEAQ 676
           E   R     +R +E K EE E++E +
Sbjct: 144 EIERRRGMMRQRAQERKNEEMEVMEVE 170


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 4/87 (4%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMA 649
           ++ Q+RL  ++L ++  E R     +  K EEERK  EE   ++  EE  +  +EA   A
Sbjct: 425 KEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKA 484

Query: 650 EKIARWEEWNKRLEEVKREERELLEAQ 676
           E+    E   K  +E +++E+ ++E Q
Sbjct: 485 EE----ELLLKEKQEQEKQEKAMIEKQ 507



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 20/67 (29%), Positives = 34/67 (50%)

Query: 603 KEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRL 662
           K + E R      +E+ E+ER   EE+   E  E   +  +E + + E+  + EE  KR 
Sbjct: 402 KILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQ 461

Query: 663 EEVKREE 669
           EE K+++
Sbjct: 462 EEEKKKQ 468



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 5/71 (7%)

Query: 605 IGEPRNYGLTDEEKAE----EERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNK 660
           +G+P   G TD  +A     E+R+ A  +  +E  E  E+E Q+ +E  E   + EE   
Sbjct: 387 LGKP-TAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERL 445

Query: 661 RLEEVKREERE 671
           RLEE  R++ E
Sbjct: 446 RLEEEARKQEE 456



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 18/130 (13%)

Query: 590 EDAQNRLAIKQLIKEIGEPRNYGLTDEEKAE-EERKAAEERLAREAAEEAEREHQEAV-- 646
           E+A+ +   + L+KE  E        +EKA  E++K A E  ARE AE+   E ++ +  
Sbjct: 478 EEAKRKAEEELLLKEKQEQEK-----QEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQ 532

Query: 647 ---EMAEKIARWEEWNKRLE------EVKREERELLEAQSIPLRNYLMTYVMPTL-IQGL 696
              E  E+  R +E  KR        +VK+E+ ++    ++ +       V   + I GL
Sbjct: 533 IEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPKVGVQPAVCVEKKTKLVVPNKMEINGL 592

Query: 697 NECCNVRPED 706
           N C  V   D
Sbjct: 593 NTCQEVNGVD 602



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 2/89 (2%)

Query: 588 KLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVE 647
           +LE+   +   ++  +E  + +  G    +  EE ++ AEE L  +  +E E++ +  +E
Sbjct: 446 RLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIE 505

Query: 648 MAEKIARWEEWNKRLEEVKREERELLEAQ 676
             ++ A  E   + + E  R ERE +  Q
Sbjct: 506 KQKEAA--ETKAREVAEQMRLEREQIMLQ 532


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 9/99 (9%)

Query: 588 KLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAV- 646
           K+ + + ++  ++ I+E  E R     +EEK  E+ K  E+       EE  RE +E + 
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQ----EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494

Query: 647 EMAEKIARWE----EWNKRLEEVKREERELLEAQSIPLR 681
           E  EK+ R E    E  K  EE KR+E+E +  Q   +R
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 533



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 37/295 (12%)

Query: 418 VGEGEEEVEEEEE-----EENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKE----KL 468
           + E EE+++E+EE     EE + + +E +   +E M +   ++  Q  + + KE    + 
Sbjct: 370 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 429

Query: 469 KSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVR---------GRMFPFDKLIIPE 519
           + M    +  I +   K ++Q K    +E  +EE+ +R          +M+  ++ I  +
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489

Query: 520 FVCALDASDEFLK-ERVINLPESI-VAGTHYSQDRFLRALSNYRDINIDDETVFNYFDEL 577
                +  ++  + E  I+  E I        Q+   R     R+     E ++   ++ 
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE----QEEIWRQKEK- 544

Query: 578 EIHPIHIDVGKLEDAQNRLAIKQLIKE--IGEPRNYGLTDEEKA---------EEERKAA 626
            IH     + K E+   R   K   +E  I E        EEK          +EE+   
Sbjct: 545 -IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603

Query: 627 EERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERELLEAQSIPLR 681
           +E + +E  E+   + ++  E  EK+   EE  +R EE  RE+ + +  Q   +R
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 57/266 (21%), Positives = 109/266 (40%), Gaps = 41/266 (15%)

Query: 418 VGEGEEEVEEEEEEENVEDAQELLDGIKES---MEQNAGQLDDQYIIRFMKEKLKSMPCR 474
           + E EE++ E+E+    E+ ++  + I+E     EQ A     +  IR  +EK++     
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE-- 497

Query: 475 NQGYILDGFPKTYDQAKDLFNQED--EEEEDDVRGRMFPFDKLIIPEFVCALDASDEFL- 531
                     K + Q + +  QE   EEE+   +  M+  ++ I  +        +E   
Sbjct: 498 ---------EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ--------EEIWR 540

Query: 532 -KERVINLPESIVAGTHYSQDRFLRALSNYRD----INIDDETVFNYFDELEIHPIHIDV 586
            KE++    E I       +++  R      D    I   +E V+   ++     I    
Sbjct: 541 QKEKIHEQEEKI----RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK-----IREQE 591

Query: 587 GKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAV 646
            K+ + + ++  ++ + +  E +  G  +E+  E+E K  E+       EE  RE ++ +
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEK-MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKI 650

Query: 647 -EMAEKIARWEEWNKRLEEVKREERE 671
            E  EKI   EE  +  EE   E+ E
Sbjct: 651 REQEEKIREQEEMMQEQEEKMWEQEE 676



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 594 NRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAE-ERLAREAAEEAEREHQEAVEMAEKI 652
           NRL  +Q  K   +       +E+  E+E K  E E   RE  E+  R+ +   E  EK+
Sbjct: 353 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412

Query: 653 ARWEE--WNKRLEEVKREERELLEAQ 676
            R EE  W K  E+++R+E  + E +
Sbjct: 413 RRQEEMMWEKE-EKMRRQEEMMWEKE 437



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 25/132 (18%), Positives = 60/132 (45%), Gaps = 7/132 (5%)

Query: 554 LRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLA-----IKQLIKEIGEP 608
           L+++S      +++  ++N  ++ +   +     K+++ + ++      I++  ++I E 
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394

Query: 609 RNYGLTDEEKA--EEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVK 666
                  EE    +EE+   +E +  E  E+  R+ +   E  EKI   EE     E+++
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454

Query: 667 REERELLEAQSI 678
            +E +  E + I
Sbjct: 455 EQEEKRQEEEKI 466



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 4/87 (4%)

Query: 615 DEEKAEEERKAAEERLAREAAEEAEREHQEAV-EMAEKIARWEE--WNKRLEEVKREERE 671
           +E+   +E K  E     +  EE  RE +E + E  EK+ R EE  W K  E+++R+E  
Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE-EKMRRQEEM 418

Query: 672 LLEAQSIPLRNYLMTYVMPTLIQGLNE 698
           + E +    R   M +     I+ L E
Sbjct: 419 MWEKEEKMRRQEEMMWEKEEKIRELEE 445



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 3/69 (4%)

Query: 615 DEEKAEEERKAAE-ERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEE-VKREEREL 672
           +E+  E+E+K  E E   RE  E  + + ++  E  EK+   EE  +  EE ++R+E ++
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699

Query: 673 LEAQSIPLR 681
            E Q + LR
Sbjct: 700 WE-QEVRLR 707



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 32/158 (20%), Positives = 67/158 (42%), Gaps = 18/158 (11%)

Query: 541 SIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIH------IDVGKLEDAQN 594
           S VA      DR++  L+  RD  +  E   N   + E+   +      + + + E ++ 
Sbjct: 243 SAVATQKKKADRYIEELTKERDA-LSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 301

Query: 595 RLAIKQLIKEIGE-----PRNYGLTDEEKAEEERKAAEERLAREAAEEA------EREHQ 643
           +L +K+L +++       P+     + +   +E ++   +L  +  E        +++ +
Sbjct: 302 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 361

Query: 644 EAVEMAEKIARWEEWNKRLEEVKREERELLEAQSIPLR 681
           +     EKI  WEE  +  EE  RE+ E +  Q   +R
Sbjct: 362 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 399


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%)

Query: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEA--EREHQEAVEMAEKIARWEEWNKRLEE 664
           E R   L ++++ E+ER A  ER  +E  E    E+E +  +E+ +++ +  E  ++ EE
Sbjct: 366 EKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREE 425

Query: 665 VKREERELLEA 675
            +R+E E  EA
Sbjct: 426 ERRKEIERREA 436


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%)

Query: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEA--EREHQEAVEMAEKIARWEEWNKRLEE 664
           E R   L ++++ E+ER A  ER  +E  E    E+E +  +E+ +++ +  E  ++ EE
Sbjct: 366 EKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREE 425

Query: 665 VKREERELLEA 675
            +R+E E  EA
Sbjct: 426 ERRKEIERREA 436


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 13/109 (11%)

Query: 576  ELEIHPIHIDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAA 635
            +LEI+ +  ++  L+D + ++  K++++EI + +    T EE A    K +EE+  ++  
Sbjct: 1266 DLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQ-KKQVD 1324

Query: 636  EEAEREHQEAVEMAEKIARWEEWNKRLEE-------VKREERELLEAQS 677
             E ER  QE     E+IAR EE   R++E       V+ EE   L A++
Sbjct: 1325 LERERASQE-----EQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEA 1368


>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
          Length = 936

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 21/53 (39%), Positives = 36/53 (67%), Gaps = 1/53 (1%)

Query: 619 AEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERE 671
           AE+++K  EE+LA+  A+E ER+ +EA E   ++ R  E  KRL+++K  E++
Sbjct: 676 AEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKRE-EKRLKKMKELEKQ 727



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 14/80 (17%)

Query: 613 LTDEEKAEEERKAA------EERLAREAAE-EAEREHQEAVEMAEKIARWEEW-----NK 660
           L +++K +EE K A      EER  REA E EA+ E +   +  +K+   E+      N+
Sbjct: 675 LAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQ 734

Query: 661 RLEEVKRE--ERELLEAQSI 678
           +LE + +E  ER LL  + +
Sbjct: 735 QLEAIAKEHYERVLLRKKGL 754


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 21/67 (31%), Positives = 36/67 (53%)

Query: 615 DEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERELLE 674
           +EEK  E+ K  EE   +E  ++  R+ ++  E  EK+ R EE  +  EE ++E+ E + 
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608

Query: 675 AQSIPLR 681
            Q   +R
Sbjct: 609 KQEEKIR 615



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 9/89 (10%)

Query: 588 KLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAV- 646
           K+ + + ++  ++ I+E  E R     +EEK  E+ K  E+       EE  RE +E + 
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQ----EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447

Query: 647 EMAEKIARWEE----WNKRLEEVKREERE 671
           E  +K+ R EE      K  EE KR+E+E
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQE 476



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 61/289 (21%), Positives = 123/289 (42%), Gaps = 25/289 (8%)

Query: 407 AKLEAIVAPNDVGEGEEEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKE 466
           AKL+A V  N++     + +EE+     E  QE  + I+E  E+   Q +    IR  +E
Sbjct: 279 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK---IREQEE 335

Query: 467 KLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDE---------EEEDDVRGR--MFPFDKL 515
           K++    R +  + +   K   Q + ++ +E++         E+E+ +R +  M    + 
Sbjct: 336 KMR----RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391

Query: 516 IIPEFVCALDASDEFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFD 575
            I E    +   ++  ++      E  +      Q++  +       I   +E +     
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451

Query: 576 EL--EIHPIHIDVGKLEDAQNRLAIKQLIKE---IGEPRNYGLTDEEKAEEERKAAEERL 630
           ++  +   IH +  K+ + + R   +++ ++   I E        E+  E+E K  ++  
Sbjct: 452 KMWRQEEKIH-EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510

Query: 631 AREAAEEAEREHQEAV-EMAEKIARWEEWNKRLEEVKREERELLEAQSI 678
                EE  RE +E + E  EK+ R EE  +  EE+ REE ++ E + I
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 4/108 (3%)

Query: 594 NRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAE-ERLAREAAEEAEREHQEAVEMAEKI 652
           NRL  +Q  K   +       +E+  E+E K  E E   RE  E+  R+ +   E  EK+
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351

Query: 653 ARWEE--WNKRLEEVKREERELLEAQSIPLRNYLMTYVMPTLIQGLNE 698
            R EE  W K  E+++R+E  + E +    R   M +     I+ L E
Sbjct: 352 RRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 398



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 54/260 (20%), Positives = 112/260 (43%), Gaps = 22/260 (8%)

Query: 422 EEEVEEEEEEENVEDAQELLDGIKESME---QNAGQLDDQYIIRFMKEKLKSMPCRNQGY 478
           +E++ EEE+ +  E+     + I E  E   Q     + +  IR  +EK+     R +  
Sbjct: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV----WRQEEK 518

Query: 479 ILDGFPKTYDQAKDLFNQEDE--EEEDDVRGRMFPFDKLIIPEFVCALDASDEFLK--ER 534
           I +   K  +Q + ++ QE++  E+E+  R      ++  I E     +  D+  +  E+
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK 578

Query: 535 VINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDEL--EIHPIHIDVGKLEDA 592
           +    E +     + Q+  +R     R     +E ++   +++  +   I     K+ + 
Sbjct: 579 IREQEEKV-----WRQEEKIREQEEKRQEQ--EEKMWKQEEKIREQEEKIQEQEEKIREQ 631

Query: 593 QNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAV-EMAEK 651
           + ++  ++ + +  E +  G  +E+  E+E K  E+       EE  RE ++ + E  EK
Sbjct: 632 EEKIREQEEMTQEQEEK-MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690

Query: 652 IARWEEWNKRLEEVKREERE 671
           I   EE  +  EE   E+ E
Sbjct: 691 IREQEEMMQEQEEKMWEQEE 710



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 3/58 (5%)

Query: 620 EEERKAAEERLAREAAEEAEREHQEAV-EMAEKIARWEEWNKRLEEVKREERELLEAQ 676
           EE+R+  EE++ ++  EE  RE +E + E  EKI   EE  +  EE+ +E+ E +  Q
Sbjct: 597 EEKRQEQEEKMWKQ--EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 616 EEKA--EEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERELL 673
           EEK   +EE+   +E   +E  E+  ++ ++  E  EKI   EE  +  EE  RE+ E+ 
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642

Query: 674 EAQ 676
           + Q
Sbjct: 643 QEQ 645



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 17/64 (26%), Positives = 32/64 (50%)

Query: 618 KAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERELLEAQS 677
           + +EE+   +E + +E  E+   + ++  E  EK+   EE   R EE  RE+ + +  Q 
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688

Query: 678 IPLR 681
             +R
Sbjct: 689 EKIR 692



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 24/273 (8%)

Query: 420 EGEEEVEEEEE-----EENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMK-EKLKSMPC 473
           E EE++  +EE     EE + + +E +   ++  EQ   + +++ I    K ++ ++   
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433

Query: 474 RNQGYILDGFPKTYDQAKDLFNQED---------EEEEDDVRGRMFPFDKLIIPEFVCAL 524
           R +  I +   K  +Q K ++ QE+         EEE+   +  M+  ++ I  +     
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493

Query: 525 DASDEFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDEL-EIHPIH 583
                  +E  I   E  V    + Q+  +R       I   +E ++   +++ E   + 
Sbjct: 494 QKEKMHEQEEKIRKQEEKV----WRQEEKIR--EQEEKIREQEEKMWRQEEKIREQEEMW 547

Query: 584 IDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQ 643
            +  K+ + Q ++  ++  +E  E + +   ++ + +EE+   +E   RE  E+ + + +
Sbjct: 548 REEEKMHE-QEKIWEEEKRQE-QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605

Query: 644 EAVEMAEKIARWEEWNKRLEEVKREERELLEAQ 676
           +  +  EKI   EE  +  EE  RE+ E +  Q
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 27/134 (20%), Positives = 63/134 (47%), Gaps = 10/134 (7%)

Query: 554 LRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLA-----IKQLIKEIGEP 608
           L+++S      +++  ++N  ++ +   +     K+++ + ++      I++  ++I E 
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333

Query: 609 RNYGLTDEEKA--EEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEE--WNKRLEE 664
                  EE    +EE+   +E +  E  E+  R+ +   E  EK+ R EE  W K  E+
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EK 392

Query: 665 VKREERELLEAQSI 678
           ++  E ++ E + I
Sbjct: 393 IRELEEKMHEQEKI 406



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 3/69 (4%)

Query: 615 DEEKAEEERKAAE-ERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEE-VKREEREL 672
           +E+  E+E+K  E E   RE  E  + + ++  E  EK+   EE  +  EE ++R+E ++
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733

Query: 673 LEAQSIPLR 681
            E Q + LR
Sbjct: 734 WE-QEVRLR 741



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 588 KLEDAQNRLAIKQLIKEIGE--PRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEA 645
           KLE A+  L  +QL  E          ++ + +A+ E      RL ++  E+  R+ ++ 
Sbjct: 250 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI 309

Query: 646 VEMAEKIARWEEWNKRLEEVKREERELLEAQ 676
            E  EKI   EE  +  EE  RE+ E +  Q
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 18/75 (24%), Positives = 34/75 (45%)

Query: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVK 666
           E + +   ++ + +EE+   +E   RE  E+   + +   E  EK+   EE     EE  
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 663

Query: 667 REERELLEAQSIPLR 681
           +E+ E +  Q   +R
Sbjct: 664 QEQEETMWRQEEKIR 678


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 34/98 (34%), Positives = 48/98 (48%), Gaps = 11/98 (11%)

Query: 588 KLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEE-------AER 640
           +LE  + +L  +Q  KE+   R      E +  E  +   ERL RE  E+        ER
Sbjct: 139 ELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQER 198

Query: 641 EHQEAVEMAEKIARWE--EWNKRL--EEVKREERELLE 674
           E QE +E  E++ R E  E  +RL  E  +R+ERE LE
Sbjct: 199 ERQERLERQERLERQERLERQERLDRERQERQERERLE 236



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 4/79 (5%)

Query: 593 QNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKI 652
           + RL  +QL +E  E        E    +ER   +ERL R+   + ER+ ++  E  E++
Sbjct: 183 RERLEQEQLERERQERER----QERLERQERLERQERLERQERLDRERQERQERERLERL 238

Query: 653 ARWEEWNKRLEEVKREERE 671
            R  +  +R E+++RE+ E
Sbjct: 239 ERERQERERQEQLEREQLE 257



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 593 QNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAR----EAAEEAEREHQEAVEM 648
           + RL  ++L +E  E        +E+  +ER   +ERL R    E  E  +RE QE  E 
Sbjct: 173 RERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQE- 231

Query: 649 AEKIARWEEWNKRLEEVKREERELLE 674
            E++ R E   +  E  ++ ERE LE
Sbjct: 232 RERLERLERERQERERQEQLEREQLE 257


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 34/98 (34%), Positives = 48/98 (48%), Gaps = 11/98 (11%)

Query: 588 KLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEE-------AER 640
           +LE  + +L  +Q  KE+   R      E +  E  +   ERL RE  E+        ER
Sbjct: 139 ELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQER 198

Query: 641 EHQEAVEMAEKIARWE--EWNKRL--EEVKREERELLE 674
           E QE +E  E++ R E  E  +RL  E  +R+ERE LE
Sbjct: 199 ERQERLERQERLERQERLERQERLDRERQERQERERLE 236



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 4/79 (5%)

Query: 593 QNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKI 652
           + RL  +QL +E  E        E    +ER   +ERL R+   + ER+ ++  E  E++
Sbjct: 183 RERLEQEQLERERQERER----QERLERQERLERQERLERQERLDRERQERQERERLERL 238

Query: 653 ARWEEWNKRLEEVKREERE 671
            R  +  +R E+++RE+ E
Sbjct: 239 ERERQERERQEQLEREQLE 257



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 593 QNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAR----EAAEEAEREHQEAVEM 648
           + RL  ++L +E  E        +E+  +ER   +ERL R    E  E  +RE QE  E 
Sbjct: 173 RERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQE- 231

Query: 649 AEKIARWEEWNKRLEEVKREERELLE 674
            E++ R E   +  E  ++ ERE LE
Sbjct: 232 RERLERLERERQERERQEQLEREQLE 257


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,412,569
Number of Sequences: 37866
Number of extensions: 1302227
Number of successful extensions: 20233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 320
Number of HSP's that attempted gapping in prelim test: 12960
Number of HSP's gapped (non-prelim): 5681
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.