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Search of human proteins with 148727264
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
(586 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148727264 transcription elongation regulator 1-like [Homo sap... 1202 0.0
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 274 1e-73
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 274 1e-73
gi|151301228 formin binding protein 3 [Homo sapiens] 75 2e-13
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 68 2e-11
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 68 2e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 54 3e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 52 2e-06
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 51 3e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 51 3e-06
gi|33286436 gametogenetin [Homo sapiens] 50 4e-06
gi|160707881 formin 2 [Homo sapiens] 49 2e-05
gi|118402590 myosin XV [Homo sapiens] 48 2e-05
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 47 6e-05
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 46 8e-05
gi|157168329 formin 1 [Homo sapiens] 46 1e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens] 46 1e-04
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 46 1e-04
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 45 1e-04
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 45 1e-04
gi|90903231 huntingtin [Homo sapiens] 45 2e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 45 2e-04
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 45 2e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 45 2e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 45 2e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 45 2e-04
gi|47825361 non-specific cytotoxic cell receptor protein 1 homol... 44 3e-04
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 44 5e-04
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 44 5e-04
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 44 5e-04
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 1202 bits (3110), Expect = 0.0
Identities = 586/586 (100%), Positives = 586/586 (100%)
Query: 1 MQAGARFQRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPP 60
MQAGARFQRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPP
Sbjct: 1 MQAGARFQRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPP 60
Query: 61 VLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGH 120
VLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGH
Sbjct: 61 VLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGH 120
Query: 121 SPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPE 180
SPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPE
Sbjct: 121 SPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPE 180
Query: 181 ESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAI 240
ESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAI
Sbjct: 181 ESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAI 240
Query: 241 ATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPAL 300
ATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPAL
Sbjct: 241 ATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPAL 300
Query: 301 MLRAQKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNP 360
MLRAQKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNP
Sbjct: 301 MLRAQKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNP 360
Query: 361 TMHLSVWEKPMDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNR 420
TMHLSVWEKPMDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNR
Sbjct: 361 TMHLSVWEKPMDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNR 420
Query: 421 TEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIV 480
TEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIV
Sbjct: 421 TEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIV 480
Query: 481 FDPRYLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKE 540
FDPRYLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKE
Sbjct: 481 FDPRYLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKE 540
Query: 541 FAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKRDKENRLRLRKMR 586
FAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKRDKENRLRLRKMR
Sbjct: 541 FAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKRDKENRLRLRKMR 586
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 274 bits (701), Expect = 1e-73
Identities = 128/274 (46%), Positives = 188/274 (68%), Gaps = 20/274 (7%)
Query: 325 EDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDRGDLNRIIE 384
E+ A+ +PVA+ P+PG+PWCVVWTGD+RVFF+NPT LS+W++P DL R D+++II+
Sbjct: 493 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 552
Query: 385 DPPHKRKLE--------------------APATDNSDGSSSEDNREDQDVKTKRNRTEGC 424
+PPHK+ +E + + + E+ ED+ VK K+ + +
Sbjct: 553 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 612
Query: 425 GSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIVFDPR 484
E+ + + + ++PLE R+ F+DMLLERGVSAFSTWEKELHKIVFDPR
Sbjct: 613 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 672
Query: 485 YLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKEFAEK 544
YLLLN +ERKQ+F+Q+VKTR +EE +EKK+K++ AKE+FKK++EE+K +PR TF EFA K
Sbjct: 673 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 732
Query: 545 YGRDQRFRLVQKRKDQEHFFNQFILILKKRDKEN 578
+ +D RF+ ++K KD+E FN+F+ +K++KE+
Sbjct: 733 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKED 766
Score = 55.1 bits (131), Expect = 2e-07
Identities = 100/460 (21%), Positives = 175/460 (38%), Gaps = 143/460 (31%)
Query: 200 VSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGP 259
VS+S PAP + P+ TV PQP P T PA+ P ++ P
Sbjct: 317 VSVSTPAPTATPVQTV---PQPHPQ--------TLPPAV--------------PHSV--P 349
Query: 260 SPSSVQPRHF-LTLAPIKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPP 318
P++ P + + P ++PL P+ G +A P M+ Q + P
Sbjct: 350 QPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPG-MAPPIVPMIHPQVAIAAS------P 402
Query: 319 PMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDRGD 378
L G +T V S W T D + +++N S WEKP +LK++
Sbjct: 403 ATLAG-------------ATAV--SEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEK 447
Query: 379 LNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNRTEGCGSPKPEEAKREDKG 438
L I++P ++ P+ + + E++ +++ +K + PK EE E+K
Sbjct: 448 LEEKIKEP-----IKEPSEEPLPMETEEEDPKEEPIKEIKE------EPKEEEMTEEEKA 496
Query: 439 TRTPPPQILLPL-----------EERVTHFRDMLLERGVSAFSTWEK--------ELHKI 479
+ P P+ +ERV + + S W++ ++ KI
Sbjct: 497 AQKAKPVATAPIPGTPWCVVWTGDERVFFYNP------TTRLSMWDRPDDLIGRADVDKI 550
Query: 480 VFDPRYLLLNSEERKQIFE-----------QFVKTRIKEE------------YKEKKSK- 515
+ +P + EE K++ QF + IKEE K KK K
Sbjct: 551 IQEPPH-KKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKR 609
Query: 516 ----------------------------LLLAKEEFKKLLEESKVSPRTTFKEFAEKYGR 547
L ++FK +L E VS +T+++ K
Sbjct: 610 DDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVF 669
Query: 548 DQRFRLVQKRKDQEHFFNQFILIL---KKRDKENRLRLRK 584
D R+ L+ K+++ F+Q++ ++R+K+N++ K
Sbjct: 670 DPRYLLLNP-KERKQVFDQYVKTRAEEERREKKNKIMQAK 708
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/205 (27%), Positives = 77/205 (37%), Gaps = 41/205 (20%)
Query: 12 RQLQQQQPRRRQPLLWP---MDAEPP---PPPPWVWMVPGSAGLLRLSAGVVVPPVLLAS 65
R QQQ R R P P M PP PPPP+ G++R G PP
Sbjct: 20 RMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPF--------GMMR---GPPPPPRPPFG 68
Query: 66 APP--PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPS 123
PP P P +P G P P P P L P P ++ P P P
Sbjct: 69 RPPFDPNMPPMPPPGGIPPPMGP--PHLQRP--PFMPPPMSSMPPP------------PG 112
Query: 124 LGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESR 183
+ PP P P L P+ + W++ + P+ K+++ N+ +S W P+ +
Sbjct: 113 MMFPPGMPPVTAPGTPALPPTE------EIWVENKTPDGKVYYYNARTRESAWTKPDGVK 166
Query: 184 FFHGHEKPRLLANQVAVSLSRPAPA 208
E +LA Q V A A
Sbjct: 167 VIQQSELTPMLAAQAQVQAQAQAQA 191
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 15/103 (14%)
Query: 456 HFRDMLLERG-VSAFSTWEKELHKIVF-DPRYLLLNSEERKQIFEQFVKTRIKEEYKEKK 513
HFR +L E ++ STW KE+ KI+ DPR + +S +RK K R EEY +
Sbjct: 939 HFRQLLDETSAITLTSTW-KEVKKIIKEDPRCIKFSSSDRK-------KQREFEEY--IR 988
Query: 514 SKLLLAKEEFKKLLEESKVSPRTTFKEFAEKYGRDQRFRLVQK 556
K + AK +F+ LL+E+K + K E DQ + V+K
Sbjct: 989 DKYITAKADFRTLLKETKFITYRSKKLIQES---DQHLKDVEK 1028
Score = 39.3 bits (90), Expect = 0.010
Identities = 57/283 (20%), Positives = 110/283 (38%), Gaps = 69/283 (24%)
Query: 352 DDRVFFFNPTMHLSVWEKPMDLKD----RGDLNRIIEDPPHKRKLEAPATDNSDGSSSED 407
D R NP V+++ + + R N+I++ +K+ A N + SE
Sbjct: 670 DPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEF 729
Query: 408 NREDQDVKTKRNRTEGCGSPKPEEA------------KREDKGTRTPPPQILLPLEERVT 455
+ K +R + K EA ++ED TR E+ +
Sbjct: 730 AAKH----AKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRG---------EKIKS 776
Query: 456 HFRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNSEE-RKQIFEQFV------------- 501
F ++L + + S W K K+ DPRY ++S R+ +F+Q++
Sbjct: 777 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 836
Query: 502 ----KTRIKEEYKEKKSKLLLAKEE--------------------FKKLLEESKVSPRTT 537
+ RI+ +E++ ++ A+ E FK LL + S +
Sbjct: 837 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS 896
Query: 538 FKEFAEKYGRDQRFR--LVQKRKDQEHFFNQFILILKKRDKEN 578
+ + +D R+ + +R+++E FN+ I L K+ +E+
Sbjct: 897 WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 939
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 274 bits (701), Expect = 1e-73
Identities = 128/274 (46%), Positives = 188/274 (68%), Gaps = 20/274 (7%)
Query: 325 EDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDRGDLNRIIE 384
E+ A+ +PVA+ P+PG+PWCVVWTGD+RVFF+NPT LS+W++P DL R D+++II+
Sbjct: 514 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 573
Query: 385 DPPHKRKLE--------------------APATDNSDGSSSEDNREDQDVKTKRNRTEGC 424
+PPHK+ +E + + + E+ ED+ VK K+ + +
Sbjct: 574 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 633
Query: 425 GSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIVFDPR 484
E+ + + + ++PLE R+ F+DMLLERGVSAFSTWEKELHKIVFDPR
Sbjct: 634 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 693
Query: 485 YLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKEFAEK 544
YLLLN +ERKQ+F+Q+VKTR +EE +EKK+K++ AKE+FKK++EE+K +PR TF EFA K
Sbjct: 694 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 753
Query: 545 YGRDQRFRLVQKRKDQEHFFNQFILILKKRDKEN 578
+ +D RF+ ++K KD+E FN+F+ +K++KE+
Sbjct: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKED 787
Score = 59.7 bits (143), Expect = 7e-09
Identities = 100/462 (21%), Positives = 178/462 (38%), Gaps = 126/462 (27%)
Query: 200 VSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGP 259
VS+S PAP + P+ TV PQP P T PA+ P ++ P
Sbjct: 317 VSVSTPAPTATPVQTV---PQPHPQ--------TLPPAV--------------PHSV--P 349
Query: 260 SPSSVQPRHF-LTLAPIKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPP 318
P++ P + + P ++PL P+ ++ P + A ++ G PP
Sbjct: 350 QPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVAT-TKTGVLPGMAPP 408
Query: 319 --PMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDR 376
PM+ A +T V S W T D + +++N S WEKP +LK++
Sbjct: 409 IVPMIHPQVAIAASPATLAGATAV--SEWTEYKTADGKTYYYNNRTLESTWEKPQELKEK 466
Query: 377 GDLNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNRTEGCGSPKPEEAKRED 436
L I++P ++ P+ + + E++ +++ +K + PK EE E+
Sbjct: 467 EKLEEKIKEP-----IKEPSEEPLPMETEEEDPKEEPIKEIKE------EPKEEEMTEEE 515
Query: 437 KGTRTPPPQILLPL-----------EERVTHFRDMLLERGVSAFSTWEK--------ELH 477
K + P P+ +ERV + + S W++ ++
Sbjct: 516 KAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNP------TTRLSMWDRPDDLIGRADVD 569
Query: 478 KIVFDPRYLLLNSEERKQIFE-----------QFVKTRIKEE------------YKEKKS 514
KI+ +P + EE K++ QF + IKEE K KK
Sbjct: 570 KIIQEPPH-KKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKR 628
Query: 515 K-----------------------------LLLAKEEFKKLLEESKVSPRTTFKEFAEKY 545
K L ++FK +L E VS +T+++ K
Sbjct: 629 KRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKI 688
Query: 546 GRDQRFRLVQKRKDQEHFFNQFILIL---KKRDKENRLRLRK 584
D R+ L+ K+++ F+Q++ ++R+K+N++ K
Sbjct: 689 VFDPRYLLLNP-KERKQVFDQYVKTRAEEERREKKNKIMQAK 729
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/205 (27%), Positives = 77/205 (37%), Gaps = 41/205 (20%)
Query: 12 RQLQQQQPRRRQPLLWP---MDAEPP---PPPPWVWMVPGSAGLLRLSAGVVVPPVLLAS 65
R QQQ R R P P M PP PPPP+ G++R G PP
Sbjct: 20 RMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPF--------GMMR---GPPPPPRPPFG 68
Query: 66 APP--PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPS 123
PP P P +P G P P P P L P P ++ P P P
Sbjct: 69 RPPFDPNMPPMPPPGGIPPPMGP--PHLQRP--PFMPPPMSSMPPP------------PG 112
Query: 124 LGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESR 183
+ PP P P L P+ + W++ + P+ K+++ N+ +S W P+ +
Sbjct: 113 MMFPPGMPPVTAPGTPALPPTE------EIWVENKTPDGKVYYYNARTRESAWTKPDGVK 166
Query: 184 FFHGHEKPRLLANQVAVSLSRPAPA 208
E +LA Q V A A
Sbjct: 167 VIQQSELTPMLAAQAQVQAQAQAQA 191
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 15/103 (14%)
Query: 456 HFRDMLLERG-VSAFSTWEKELHKIVF-DPRYLLLNSEERKQIFEQFVKTRIKEEYKEKK 513
HFR +L E ++ STW KE+ KI+ DPR + +S +RK K R EEY +
Sbjct: 960 HFRQLLDETSAITLTSTW-KEVKKIIKEDPRCIKFSSSDRK-------KQREFEEY--IR 1009
Query: 514 SKLLLAKEEFKKLLEESKVSPRTTFKEFAEKYGRDQRFRLVQK 556
K + AK +F+ LL+E+K + K E DQ + V+K
Sbjct: 1010 DKYITAKADFRTLLKETKFITYRSKKLIQES---DQHLKDVEK 1049
Score = 39.3 bits (90), Expect = 0.010
Identities = 57/283 (20%), Positives = 110/283 (38%), Gaps = 69/283 (24%)
Query: 352 DDRVFFFNPTMHLSVWEKPMDLKD----RGDLNRIIEDPPHKRKLEAPATDNSDGSSSED 407
D R NP V+++ + + R N+I++ +K+ A N + SE
Sbjct: 691 DPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEF 750
Query: 408 NREDQDVKTKRNRTEGCGSPKPEEA------------KREDKGTRTPPPQILLPLEERVT 455
+ K +R + K EA ++ED TR E+ +
Sbjct: 751 AAKH----AKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRG---------EKIKS 797
Query: 456 HFRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNSEE-RKQIFEQFV------------- 501
F ++L + + S W K K+ DPRY ++S R+ +F+Q++
Sbjct: 798 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 857
Query: 502 ----KTRIKEEYKEKKSKLLLAKEE--------------------FKKLLEESKVSPRTT 537
+ RI+ +E++ ++ A+ E FK LL + S +
Sbjct: 858 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS 917
Query: 538 FKEFAEKYGRDQRFR--LVQKRKDQEHFFNQFILILKKRDKEN 578
+ + +D R+ + +R+++E FN+ I L K+ +E+
Sbjct: 918 WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 960
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 74.7 bits (182), Expect = 2e-13
Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 9/173 (5%)
Query: 415 KTKRNRTEGCGSPKPEEAKRED-KGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWE 473
+T + T +PK EE + + K T T + EE F+++L E+ V + ++WE
Sbjct: 335 ETSKQETVADFTPKKEEEESQPAKKTYTWNTK-----EEAKQAFKELLKEKRVPSNASWE 389
Query: 474 KELHKIVFDPRY-LLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLE-ESK 531
+ + I+ DPRY L E+KQ F + KEE +E +SK AKE F++ LE K
Sbjct: 390 QAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEK 449
Query: 532 VSPRTTFKEFAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKRDKENRLRLRK 584
++ T +K+ + +G + + + +R D+ + + L K++KE +LRK
Sbjct: 450 MTSTTRYKKAEQMFGEMEVWNAISER-DRLEIYEDVLFFLSKKEKEQAKQLRK 501
Score = 30.4 bits (67), Expect = 4.7
Identities = 39/196 (19%), Positives = 76/196 (38%), Gaps = 22/196 (11%)
Query: 143 PSALATPIGK-----SWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPRLL--- 194
P L TP + W + + + K ++ NS +S W P+E G++ +
Sbjct: 144 PDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSL 203
Query: 195 ---ANQVAVSLSRPAPASRPLPTVVLAPQP---IPGGCHNSLKVTSSPAIAIATAAAAAM 248
+N A+ + + T AP P IP ++ A+ A AAAAA
Sbjct: 204 ITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAA 263
Query: 249 VSVDPENLRGPSPSSVQ------PRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPALML 302
+ N + ++V P +T + + V+ + E+ ++ PA+
Sbjct: 264 AAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQD 323
Query: 303 RAQK--SRDGDKEDKE 316
++ + S G++ K+
Sbjct: 324 QSVEVSSNTGEETSKQ 339
Score = 30.0 bits (66), Expect = 6.2
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 343 SPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLK 374
S W + D R +++N S WEKP DLK
Sbjct: 117 SMWTEHKSPDGRTYYYNTETKQSTWEKPDDLK 148
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
sapiens]
Length = 858
Score = 68.2 bits (165), Expect = 2e-11
Identities = 78/370 (21%), Positives = 152/370 (41%), Gaps = 60/370 (16%)
Query: 261 PSSVQPRHFLTLAP-IKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDG-----DKED 314
P V P L P + + T+P +DT + PP + + DG + +D
Sbjct: 50 PGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADD 109
Query: 315 K----EPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKP 370
K E P +L + A + PW + + +++N S W +P
Sbjct: 110 KQSVWEKPSVL-----------KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRP 158
Query: 371 MDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDN---------------------- 408
DL D L + ++ K++ + P T + +
Sbjct: 159 KDLDDLEVL--VKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGG 216
Query: 409 REDQDVKTK---------RNRTEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTH--- 456
ED DV + EG S + ++E++ ++ P + L R
Sbjct: 217 SEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQA 276
Query: 457 FRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNS-EERKQIFEQFVKTRIKEEYKEKKSK 515
F+++L ++ V + ++WE+ + +V DPRY L E+KQ F + R KEE +E + +
Sbjct: 277 FKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLR 336
Query: 516 LLLAKEEFKKLLEE-SKVSPRTTFKEFAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKR 574
AK+ + LE+ +++ T ++ + +G + + +V +R D++ ++ + L K+
Sbjct: 337 AKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER-DRKEVYDDVLFFLAKK 395
Query: 575 DKENRLRLRK 584
+KE +LR+
Sbjct: 396 EKEQAKQLRR 405
Score = 38.5 bits (88), Expect = 0.017
Identities = 50/222 (22%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG-----LPGWPA 82
PM PP PP M PG ++PP+L PP +PG +PG
Sbjct: 17 PMSQRPPAIPP---MPPG-----------ILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 62
Query: 83 PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQ---------WLFGGHSPSLGLPPSSTVE 133
P+ PV + S+A A P AL + + S+ PS
Sbjct: 63 PAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKS 122
Query: 134 LVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHP-----------EES 182
+ CP W + + K ++ N+ + +S W P +E+
Sbjct: 123 KAELLLSQCP----------WKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 172
Query: 183 RFFHGHEKPRLLANQVAVSLSRP---APASRPLPTVVLAPQP 221
+ P+ L Q P P P+PT +L P+P
Sbjct: 173 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 214
>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
sapiens]
Length = 871
Score = 68.2 bits (165), Expect = 2e-11
Identities = 78/370 (21%), Positives = 152/370 (41%), Gaps = 60/370 (16%)
Query: 261 PSSVQPRHFLTLAP-IKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDG-----DKED 314
P V P L P + + T+P +DT + PP + + DG + +D
Sbjct: 56 PGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADD 115
Query: 315 K----EPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKP 370
K E P +L + A + PW + + +++N S W +P
Sbjct: 116 KQSVWEKPSVL-----------KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRP 164
Query: 371 MDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDN---------------------- 408
DL D L + ++ K++ + P T + +
Sbjct: 165 KDLDDLEVL--VKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGG 222
Query: 409 REDQDVKTK---------RNRTEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTH--- 456
ED DV + EG S + ++E++ ++ P + L R
Sbjct: 223 SEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQA 282
Query: 457 FRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNS-EERKQIFEQFVKTRIKEEYKEKKSK 515
F+++L ++ V + ++WE+ + +V DPRY L E+KQ F + R KEE +E + +
Sbjct: 283 FKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLR 342
Query: 516 LLLAKEEFKKLLEE-SKVSPRTTFKEFAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKR 574
AK+ + LE+ +++ T ++ + +G + + +V +R D++ ++ + L K+
Sbjct: 343 AKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER-DRKEVYDDVLFFLAKK 401
Query: 575 DKENRLRLRK 584
+KE +LR+
Sbjct: 402 EKEQAKQLRR 411
Score = 38.5 bits (88), Expect = 0.017
Identities = 50/222 (22%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG-----LPGWPA 82
PM PP PP M PG ++PP+L PP +PG +PG
Sbjct: 23 PMSQRPPAIPP---MPPG-----------ILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 68
Query: 83 PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQ---------WLFGGHSPSLGLPPSSTVE 133
P+ PV + S+A A P AL + + S+ PS
Sbjct: 69 PAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKS 128
Query: 134 LVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHP-----------EES 182
+ CP W + + K ++ N+ + +S W P +E+
Sbjct: 129 KAELLLSQCP----------WKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 178
Query: 183 RFFHGHEKPRLLANQVAVSLSRP---APASRPLPTVVLAPQP 221
+ P+ L Q P P P+PT +L P+P
Sbjct: 179 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 220
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 54.3 bits (129), Expect = 3e-07
Identities = 80/337 (23%), Positives = 116/337 (34%), Gaps = 63/337 (18%)
Query: 3 AGARFQRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVL 62
+GA F+ + Q Q + Q L+ P PPPPPP PGSA + +L P +
Sbjct: 680 SGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA-MAQLKPAPCAPSLP 738
Query: 63 LASAPPP-------------AAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFP 109
SAPPP A P P P PAP P P PL + P + P
Sbjct: 739 QFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP-- 796
Query: 110 ALHGQWLFGGHSPSLGLPPSSTVELVPVFP--HLCPSALATPIGKSWIDKRIPNCKIFFN 167
+ +P PP + P FP ++ PS P+ +P +
Sbjct: 797 ------VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV-------PVPPPTLPKQ 843
Query: 168 NSFALDSTWIHPEESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCH 227
SF P S + +A+Q + PA S+PL +P+P
Sbjct: 844 QSFC-----AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPL-------KPVPA--- 888
Query: 228 NSLKVTSSPAIAIATAAAAAMVSVDPENLRGPSPSS-----VQPRHFLTLAPIKIPLRTS 282
++ S PA+ + + V + P P S P + P P S
Sbjct: 889 -NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS 947
Query: 283 PVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPPP 319
P D G+ + S+ K+PPP
Sbjct: 948 PTPDKSGSPGK-----------KTSKTSSPGGKKPPP 973
Score = 39.3 bits (90), Expect = 0.010
Identities = 77/339 (22%), Positives = 113/339 (33%), Gaps = 28/339 (8%)
Query: 9 RRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPP 68
+R QL++ R + + P + PP P +V P + P
Sbjct: 582 KRGTQLEESSKARMESMNRPYTSLVPPLSP---------------QPKIVTPYTASQPSP 626
Query: 69 PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAH-PFPALHGQWLFGGHSPSLGLP 127
P P P P P P P P LP SAP + +AA + + HS +L P
Sbjct: 627 PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP 686
Query: 128 PSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHG 187
P+ V + P L P G P + L P +F
Sbjct: 687 PTPP---VMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQF--S 741
Query: 188 HEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAA 247
P L +QV +++ AP + P P + P P+P VT + T A
Sbjct: 742 APPPPLKIHQVQ-HITQVAPPTPPPPPPI--PAPLPPQAPPKPLVTIPAPTSTKTVAPVV 798
Query: 248 MVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTR--TERGRVARPPALMLRAQ 305
+ P P+ QP + P P PV ++ A+PP L
Sbjct: 799 TQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV 858
Query: 306 KSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSP 344
S + PPP +S + +PV + P SP
Sbjct: 859 PSVVKQIASQFPPPPTPPAMES--QPLKPVPANVAPQSP 895
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 51.6 bits (122), Expect = 2e-06
Identities = 80/289 (27%), Positives = 114/289 (39%), Gaps = 51/289 (17%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGL-LRLSAGVVVP---PVLLASAPPPAAPLLPGLPGWP-- 81
P+ + P P P SA L + +SA + V P LL S PP AP++P PG P
Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSL 1493
Query: 82 -----APSEPVLPLLPLPSAPD-SAAAAAAHPFPALHGQWLFGGHSPSLG--LPPSSTVE 133
+PS L L L +AP S++ HP H P L + P+ +
Sbjct: 1494 APSGASPSASAL-TLGLATAPSLSSSQTPGHPLLLAP----TSSHVPGLNSTVAPACSPV 1548
Query: 134 LVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESRF-FHGHEKPR 192
LVP SALA+P + N ++ + P S
Sbjct: 1549 LVPA------SALASPFPSA-------------PNPAPAQASLLAPASSASQALATPLAP 1589
Query: 193 LLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVD 252
+ A Q A+ PAP PLP VLAP P S + T P +A ++ ++ S
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLP--VLAPSPGAAPVLASSQ-TPVPVMAPSSTPGTSLASAS 1646
Query: 253 PENLRGPSPSSV-QPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPAL 300
P P+P+ V P T+ P +P + T+T +A PAL
Sbjct: 1647 PV----PAPTPVLAPSSTQTMLPAPVPSPLPSPASTQT----LALAPAL 1687
Score = 40.4 bits (93), Expect = 0.005
Identities = 71/296 (23%), Positives = 110/296 (37%), Gaps = 70/296 (23%)
Query: 24 PLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAP 83
P+L P + P P +P A L+ + P L S+P L G P P P
Sbjct: 1653 PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFP 1712
Query: 84 SEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCP 143
++ L L P A++ P PA Q L P LG P+ T+ L P P L P
Sbjct: 1713 TQ-TLSLTP---------ASSLVPTPA---QTLSLAPGPPLG--PTQTLSLAPA-PPLAP 1756
Query: 144 SALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPRLLANQVAVSLS 203
A+P+G + P + L + S S
Sbjct: 1757 ---ASPVGPA-------------------------PAHT----------LTLAPASSSAS 1778
Query: 204 RPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGPSPSS 263
APAS + T+ L+P P+P +L ++ +A+A A+ + S + S ++
Sbjct: 1779 LLAPAS--VQTLTLSPAPVP-----TLGPAAAQTLALAPASTQSPASQASSLVVSASGAA 1831
Query: 264 VQPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPPP 319
P ++ P+ + DT T R PP+ S G + ++PPP
Sbjct: 1832 PLPVTMVSRLPV-----SKDEPDTLTLRSGPPSPPS----TATSFGGPRPRRQPPP 1878
Score = 36.6 bits (83), Expect = 0.066
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 21/128 (16%)
Query: 26 LWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSE 85
L P+ PPP P SA V+P L+ SA P PL+P S
Sbjct: 1019 LGPVPVRPPPGPEL------SAQPTPGPVPQVLPASLMVSASPAGPPLIPA-------SR 1065
Query: 86 PVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSA 145
P P+L P P+S + P P G PP+ T+ L P P +
Sbjct: 1066 PPGPVLLPPLQPNSGSLPQVLPSPL--------GVLSGTSRPPTPTLSLKPTPPAPVRLS 1117
Query: 146 LATPIGKS 153
A P G S
Sbjct: 1118 PAPPPGSS 1125
Score = 33.1 bits (74), Expect = 0.73
Identities = 72/271 (26%), Positives = 103/271 (38%), Gaps = 61/271 (22%)
Query: 33 PPPPPPWVWMVPGSA-GLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGW---PAPSE--- 85
P P P V ++P S G+ +P L A+ PP G+ AP +
Sbjct: 1265 PTPGPTPVSVLPSSTPSTTPAPTGLSLP--LAANQVPPTMVNNTGVVKIVVRQAPRDGLT 1322
Query: 86 PVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLP--PSSTVELVPVFPHLCP 143
PV PL P P P S A +P P L L +P+LG P T LV
Sbjct: 1323 PVPPLAPAPRPPSSGLPAVLNPRPTLTPGRL---PTPTLGTARAPMPTPTLVR------- 1372
Query: 144 SALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPRLLANQVAVSLS 203
P K+ + S PE S G P +++ + V S
Sbjct: 1373 ----------------PLLKLVHSPS---------PEVSASAPG-AAPLTISSPLHVPSS 1406
Query: 204 RPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIAT---AAAAAMVSVD---PENLR 257
P PAS P+P +P P S+ ++SS I++ T A A+A +++ P +
Sbjct: 1407 LPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVS 1466
Query: 258 GPSP---SSVQPRHFLTLAPIKIPLRTSPVS 285
P +SV P LAP+ +P P S
Sbjct: 1467 ASGPALLTSVTP----PLAPV-VPAAPGPPS 1492
Score = 32.3 bits (72), Expect = 1.2
Identities = 72/272 (26%), Positives = 104/272 (38%), Gaps = 41/272 (15%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPA--------APLLPGLPG 79
P+ P PPPP + P S+ PP A PPPA +PLL G P
Sbjct: 2478 PVHILPSPPPP-SQIPPCSSPACTPPPACTPPP---AHTPPPAQTCLVTPSSPLLLGPPS 2533
Query: 80 WPAPSEPVLPLLPLPSAPDSAAAAAAHPFP-ALHGQWLFGGHSPSLGLPPSS-----TVE 133
P + + LPL P++ A A P +L + + SL L P VE
Sbjct: 2534 VPISAS--VTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVE 2591
Query: 134 LVPVFP---HLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDST-WIHPEESRFFHGHE 189
++PV L PSA + + IPN + A +T + PE G E
Sbjct: 2592 ILPVSEKNLSLTPSAPSLTLEAG----SIPNGQEQEAPDSAEGTTLTVLPE------GEE 2641
Query: 190 KPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSP----AIAIATAAA 245
P ++ + L A + PL + A + + TSSP + A AA
Sbjct: 2642 LPLCVSESNGLELPPSAASDEPLQEPLEADR-TSEELTEAKTPTSSPEKPQELVTAEVAA 2700
Query: 246 AAMVSVDPENLRGPSPSSVQPRHFLTLAPIKI 277
+ S + GPSP+ +P T A ++I
Sbjct: 2701 PSTSSSATSSPEGPSPA--RPPRRRTSADVEI 2730
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 50.8 bits (120), Expect = 3e-06
Identities = 53/173 (30%), Positives = 64/173 (36%), Gaps = 32/173 (18%)
Query: 30 DAEPPPPPPWVWMVPGSAGL---LRLSAGVVVPPV--LLASAP-PPAAPLLPGLPGWPAP 83
DA PPPPP +P G+ L G +PP L SA PP P LPG G P P
Sbjct: 639 DATIPPPPP----LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 694
Query: 84 SEPV-----LPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVF 138
P+ +P P P P PFP G P +G+PP P F
Sbjct: 695 PPPLPGEAGMP-PPPPPLPGGPGIPPPPPFPGGPG---IPPPPPGMGMPPP------PPF 744
Query: 139 PHLCPSALATPIG-------KSWIDKRIPNCKIFFNNSFALDSTWIHPEESRF 184
P+A P G K + R PN + D W +E RF
Sbjct: 745 GFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRF 797
Score = 37.4 bits (85), Expect = 0.039
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 26/123 (21%)
Query: 53 SAGVVVPPVLLASAPPPAAPLLPG-----LPGWPAPSEPVLPLLPLP------------- 94
+A + VPP + + AP P AP LPG +P PAP + P P P
Sbjct: 558 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 617
Query: 95 --SAPDSAAAAAAHPFPALHGQWLFGGHSP---SLGLPPSSTV---ELVPVFPHLCPSAL 146
S P A P P L G P +G+P S++ +P P L SA
Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 677
Query: 147 ATP 149
P
Sbjct: 678 IPP 680
Score = 33.9 bits (76), Expect = 0.43
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 7/63 (11%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLP-GWPAPSEP 86
P +A PPPPP + PG G +PP PPP + P P G+ P+ P
Sbjct: 699 PGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP------PPPGMGMPPPPPFGFGVPAAP 752
Query: 87 VLP 89
VLP
Sbjct: 753 VLP 755
Score = 30.8 bits (68), Expect = 3.6
Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 16/116 (13%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASA-----PPPAAPLLPGLPGWPAPSEPVL 88
PP P VP + L S ++ PP + PPP P P LPG S P
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP-- 621
Query: 89 PLLP-----LPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFP 139
P LP P P S A P P G G SPS LP + + P P
Sbjct: 622 PSLPGGTAISPPPPLSGDATIPPPPPLPEG---VGIPSPS-SLPGGTAIPPPPPLP 673
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 50.8 bits (120), Expect = 3e-06
Identities = 53/173 (30%), Positives = 64/173 (36%), Gaps = 32/173 (18%)
Query: 30 DAEPPPPPPWVWMVPGSAGL---LRLSAGVVVPPV--LLASAP-PPAAPLLPGLPGWPAP 83
DA PPPPP +P G+ L G +PP L SA PP P LPG G P P
Sbjct: 648 DATIPPPPP----LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 703
Query: 84 SEPV-----LPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVF 138
P+ +P P P P PFP G P +G+PP P F
Sbjct: 704 PPPLPGEAGMP-PPPPPLPGGPGIPPPPPFPGGPG---IPPPPPGMGMPPP------PPF 753
Query: 139 PHLCPSALATPIG-------KSWIDKRIPNCKIFFNNSFALDSTWIHPEESRF 184
P+A P G K + R PN + D W +E RF
Sbjct: 754 GFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRF 806
Score = 37.4 bits (85), Expect = 0.039
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 26/123 (21%)
Query: 53 SAGVVVPPVLLASAPPPAAPLLPG-----LPGWPAPSEPVLPLLPLP------------- 94
+A + VPP + + AP P AP LPG +P PAP + P P P
Sbjct: 567 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 626
Query: 95 --SAPDSAAAAAAHPFPALHGQWLFGGHSP---SLGLPPSSTV---ELVPVFPHLCPSAL 146
S P A P P L G P +G+P S++ +P P L SA
Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686
Query: 147 ATP 149
P
Sbjct: 687 IPP 689
Score = 33.9 bits (76), Expect = 0.43
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 7/63 (11%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLP-GWPAPSEP 86
P +A PPPPP + PG G +PP PPP + P P G+ P+ P
Sbjct: 708 PGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP------PPPGMGMPPPPPFGFGVPAAP 761
Query: 87 VLP 89
VLP
Sbjct: 762 VLP 764
Score = 30.8 bits (68), Expect = 3.6
Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 16/116 (13%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASA-----PPPAAPLLPGLPGWPAPSEPVL 88
PP P VP + L S ++ PP + PPP P P LPG S P
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP-- 630
Query: 89 PLLP-----LPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFP 139
P LP P P S A P P G G SPS LP + + P P
Sbjct: 631 PSLPGGTAISPPPPLSGDATIPPPPPLPEG---VGIPSPS-SLPGGTAIPPPPPLP 682
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 50.4 bits (119), Expect = 4e-06
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 15/129 (11%)
Query: 19 PRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLP 78
PRRR L PPPPP + PG R + ++ PP + AP P+ PG P
Sbjct: 376 PRRRAAALSGPWGSPPPPPEQIHSAPGPR---RPAPALLAPPTFIFPAPTNGEPMRPGPP 432
Query: 79 GWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVF 138
G LP LP P+ P + A P P L +P LG S+ L P
Sbjct: 433 GLQE-----LPPLPPPTPPPTLQPPALQPTPLPVAPPL----TPGLGHKESA---LAPTA 480
Query: 139 PHLCPSALA 147
P ALA
Sbjct: 481 APALPPALA 489
Score = 33.9 bits (76), Expect = 0.43
Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 16/99 (16%)
Query: 12 RQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPG---SAGLLRLSAGVVVPPVLLASAPP 68
++L P P L P +P P P + PG L +A +PP L A
Sbjct: 435 QELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQA- 493
Query: 69 PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHP 107
PAPS P + PS P SA A AA P
Sbjct: 494 ------------PAPSPAPAPTVAEPSPPVSAPAPAAAP 520
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/105 (37%), Positives = 45/105 (42%), Gaps = 13/105 (12%)
Query: 33 PPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAP-PPAAPLLPGL---PGWPAPSEPVL 88
PPPPPP +PG S + PP L + PP P LPG P P P +L
Sbjct: 877 PPPPPP----LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL 932
Query: 89 PLLPLPSA----PDSAAAAAAHPFPALHGQWL-FGGHSPSLGLPP 128
PL PLP A P AA P P L G + P G+PP
Sbjct: 933 PLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/126 (32%), Positives = 49/126 (38%), Gaps = 36/126 (28%)
Query: 24 PLLWPMDAEPPPPPPWVWMVPGS----------AGLLRL----SAGVVVPPVLLASAPPP 69
P L + PPPPPP +PG+ AG+L L AG+ PP L +A PP
Sbjct: 900 PPLQGTEMLPPPPPP----LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP 955
Query: 70 -------AAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSP 122
PL P LPG P P LP +P P A P P P
Sbjct: 956 PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-----------P 1004
Query: 123 SLGLPP 128
G+PP
Sbjct: 1005 GAGIPP 1010
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/132 (32%), Positives = 56/132 (42%), Gaps = 19/132 (14%)
Query: 33 PPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG--------LPGWPAPS 84
PPPPP +P L R+ G+ PP L + PP P LPG LPG P
Sbjct: 1130 PPPPPLPGAGIPPPPPLPRV--GIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGIPP 1186
Query: 85 EPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSL-----GLPPSSTVEL--VPV 137
P LP + +P P A P P L G + +P L G+PP + + P+
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPP-PPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPL 1245
Query: 138 FPHLCPSALATP 149
P + S L TP
Sbjct: 1246 LPQVGSSTLPTP 1257
Score = 40.0 bits (92), Expect = 0.006
Identities = 39/117 (33%), Positives = 45/117 (38%), Gaps = 38/117 (32%)
Query: 34 PPPPPWVWMVPGSAGLLRL----SAGVVVPPVLLASAPPPAA----------PLLPG--- 76
PPPPP +PG AG+L L AG+ PP L +A PP P LPG
Sbjct: 921 PPPPP----LPG-AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975
Query: 77 -----LPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPP 128
LPG P P LP +P P A P P P G+PP
Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-----------PGAGIPP 1021
Score = 39.7 bits (91), Expect = 0.008
Identities = 36/114 (31%), Positives = 43/114 (37%), Gaps = 32/114 (28%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG--------LPGWPAPSE 85
PPPPP +PG AG+ PP L + PP P LPG LPG P
Sbjct: 1064 PPPPP----LPG--------AGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGIPPP 1110
Query: 86 PVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFP 139
P LP +P P A P P P G+PP + V + P
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPL-----------PGAGIPPPPPLPRVGIPP 1153
Score = 38.5 bits (88), Expect = 0.017
Identities = 34/103 (33%), Positives = 39/103 (37%), Gaps = 32/103 (31%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG--------LPGWPAPSE 85
PPPPP +PG AG+ PP L + PP P LPG LPG P
Sbjct: 976 PPPPP----LPG--------AGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPP 1022
Query: 86 PVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPP 128
P LP +P P A P P P G+PP
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPL-----------PGAGIPP 1054
Score = 38.5 bits (88), Expect = 0.017
Identities = 34/103 (33%), Positives = 39/103 (37%), Gaps = 32/103 (31%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG--------LPGWPAPSE 85
PPPPP +PG AG+ PP L + PP P LPG LPG P
Sbjct: 1009 PPPPP----LPG--------AGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPP 1055
Query: 86 PVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPP 128
P LP +P P A P P P G+PP
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPL-----------PGAGIPP 1087
Score = 37.7 bits (86), Expect = 0.030
Identities = 35/106 (33%), Positives = 43/106 (40%), Gaps = 27/106 (25%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPL 93
PPPPP +PG AG+ PP L + PP P LPG G P P P LP + +
Sbjct: 1108 PPPPP----LPG--------AGIPPPPPLPGAGIPPP-PPLPG-AGIPPP--PPLPRVGI 1151
Query: 94 PSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFP 139
P P A P P P G+PP + V + P
Sbjct: 1152 PPPPPLPGAGIPPPPPL-----------PGAGIPPPPPLPGVGIPP 1186
Score = 37.0 bits (84), Expect = 0.050
Identities = 33/103 (32%), Positives = 38/103 (36%), Gaps = 32/103 (31%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG--------LPGWPAPSE 85
PPPPP +PG AG+ PP L + PP P LPG LPG P
Sbjct: 1042 PPPPP----LPG--------AGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPP 1088
Query: 86 PVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPP 128
P LP +P P P P P G+PP
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPL-----------PGAGIPP 1120
Score = 35.0 bits (79), Expect = 0.19
Identities = 37/137 (27%), Positives = 46/137 (33%), Gaps = 39/137 (28%)
Query: 31 AEPPPPPPWVWMV----PGS------------------AGLLRLSAGVVVPPVL------ 62
++PPPPP +W PGS + + S + PP L
Sbjct: 808 SQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESS 867
Query: 63 -----LASAPPPAAPL----LPGLPGWPAPSEPVLP-LLPLPSAPDSAAAAAAHPFPALH 112
L PPP PL +P LP P P L LP P A P P L
Sbjct: 868 SSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP 927
Query: 113 GQWLFG-GHSPSLGLPP 128
G + P G+PP
Sbjct: 928 GAGILPLPPLPGAGIPP 944
Score = 33.5 bits (75), Expect = 0.56
Identities = 39/124 (31%), Positives = 51/124 (41%), Gaps = 26/124 (20%)
Query: 8 QRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGS-AGLLR--------------- 51
Q++++QLQ Q +++Q EP PP V PG+ GL R
Sbjct: 207 QQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGS 266
Query: 52 ------LSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAA 105
LSA +P L A P P PG G P P LP P+A DS ++ A
Sbjct: 267 PDTEQALSALSDLPESLAAEPREPQQPPSPG--GLPVSEAPSLPAAQ-PAAKDS-PSSTA 322
Query: 106 HPFP 109
PFP
Sbjct: 323 FPFP 326
Score = 32.3 bits (72), Expect = 1.2
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 33 PPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLP 92
PPPP P + + P A L + PP LL + P PLLP + P+ V LP
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGP---PLLPQVGSSTLPTPQVCGFLP 1264
Query: 93 LP 94
P
Sbjct: 1265 PP 1266
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 48.1 bits (113), Expect = 2e-05
Identities = 100/364 (27%), Positives = 124/364 (34%), Gaps = 59/364 (16%)
Query: 14 LQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSA--GVVVPPVLLASAPPPAA 71
L++ QPR R DA PP P P L SA VPP +S PPPA
Sbjct: 628 LRRAQPRARSS----NDARRPPAPQ-----PAPRTLSHWSALLSPPVPPRPPSSGPPPAP 678
Query: 72 PLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLG--LPPS 129
PL P L G P P+ P L P AA AH PA W P++ +PP
Sbjct: 679 PLSPALSGLPRPASPYGSLRRHP----PPWAAPAHVPPAPQASWWAFVEPPAVSPEVPPD 734
Query: 130 STVELVP--------------VFPHLCP--------SALATPIGKSWIDKRIPNCKIFFN 167
P FP P S LA+P + C
Sbjct: 735 LLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAP 794
Query: 168 NSFALDSTWIHPEESRFFHGHEKPRLLANQVAV--SLSRPAPASRPLPTVVLAPQPIPGG 225
S L S P + F +PR L A + R P PLP P P G
Sbjct: 795 PSPQL-SLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGL 853
Query: 226 CHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGPS---PSSVQPRHFLTLAPIKIPLRTS 282
CH+ + SS + +S P P P PR AP++ R S
Sbjct: 854 CHSPRR--SSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLE--HRES 909
Query: 283 PVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPPPMLGGGEDSTARG-NRPVASTPVP 341
P +E P A S D D + PP G + RG +RP PVP
Sbjct: 910 PREPEDSETPWTVPPLA------PSWDVDMPPTQRPPSPWPGGAGSRRGFSRP---PPVP 960
Query: 342 GSPW 345
+P+
Sbjct: 961 ENPF 964
Score = 37.0 bits (84), Expect = 0.050
Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 9/101 (8%)
Query: 11 RRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPA 70
R Q ++QPL + + P PP P S G G PVLL + P P
Sbjct: 2467 REMTLQATALQQQPLSAALRSLPAEKPPAPEAQPTSVG-----TGPPAKPVLLRATPKPL 2521
Query: 71 APLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPAL 111
AP P AP P+ P+ A D A+ P P L
Sbjct: 2522 AP----APLAKAPRLPIKPVAAPVLAQDQASPETTSPSPEL 2558
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 46.6 bits (109), Expect = 6e-05
Identities = 42/124 (33%), Positives = 56/124 (45%), Gaps = 7/124 (5%)
Query: 19 PRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPP-PAAPLLPGL 77
P QP+L + + P P GS LL A + PP L + +PP P P+ P L
Sbjct: 402 PEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSL 461
Query: 78 PGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALH--GQWLFGGHSPSLGLPPSSTVELV 135
PG + S +P P AP +A+ A P P L + L G P+ LPP + E
Sbjct: 462 PGTTSGSLSSVPGAP---APPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAF 518
Query: 136 PVFP 139
P FP
Sbjct: 519 P-FP 521
Score = 38.1 bits (87), Expect = 0.023
Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 19/92 (20%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAP----------PPAAPLLPGL 77
P +PP P ++ G GL L G PP+ AS+P PP P P L
Sbjct: 759 PSLLQPPGP-----LLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCL 813
Query: 78 PGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFP 109
P P P L P P+ P +A A H P
Sbjct: 814 P----PESPASALEPEPARPPLSALAPPHGSP 841
Score = 37.7 bits (86), Expect = 0.030
Identities = 41/126 (32%), Positives = 49/126 (38%), Gaps = 14/126 (11%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPA----- 82
P+ PPP P + G+L G P LL P PL PG P P+
Sbjct: 544 PLSLGQPPPSPL--LNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVAS 601
Query: 83 -PSEPVLPLLPLPSAPDSAAAAAAHPFPAL-----HGQWLFGGHSPSLGLPPSSTVELVP 136
P LLP PSAP S A+ P AL G+ G G P S +L P
Sbjct: 602 LLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSP 661
Query: 137 -VFPHL 141
+FP L
Sbjct: 662 LLFPPL 667
Score = 34.3 bits (77), Expect = 0.33
Identities = 74/286 (25%), Positives = 100/286 (34%), Gaps = 53/286 (18%)
Query: 68 PPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSA-AAAAAHPFPA---LHGQWLFGGHSPS 123
PP PL G P V P + P A P P+ ++L G++PS
Sbjct: 152 PPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPS 211
Query: 124 LGLPPSSTVEL--------VPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDST 175
PP + L + L PS L +P P+ F+ S AL
Sbjct: 212 PAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPH-ASSSPPSDPPLFHCSDALTPP 270
Query: 176 WIHPEESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSS 235
+ P + H P A+Q VS A+ LP +VL P GG +
Sbjct: 271 PLPPSNN--LPAHPGP---ASQPPVS-----SATMHLP-LVLGPL---GGAPTVEGPGAP 316
Query: 236 PAIAIATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTERGRVA 295
P +A + +AAA P P PS++Q R AP S S R + R
Sbjct: 317 PFLASSLLSAAAKAQHPPL----PPPSTLQGRRPRAQAP-----SASHSSSLRPSQRRPR 367
Query: 296 RPPALMLRAQKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVP 341
RPP + +L G T R +RP A PVP
Sbjct: 368 RPPTVFR-----------------LLEGRGPQTPRRSRPRAPAPVP 396
Score = 34.3 bits (77), Expect = 0.33
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 14/123 (11%)
Query: 33 PPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLP 92
PPP P + PG L ++PP PPP+AP PS + LP
Sbjct: 578 PPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP----------PSNLLASFLP 627
Query: 93 L----PSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALAT 148
L P+A D +A P+ G SP L P S+ L+ + L + L
Sbjct: 628 LLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDP 687
Query: 149 PIG 151
P G
Sbjct: 688 PSG 690
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 46.2 bits (108), Expect = 8e-05
Identities = 44/135 (32%), Positives = 52/135 (38%), Gaps = 31/135 (22%)
Query: 16 QQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVV----------PPVLLAS 65
+Q+ RR++PL PPPPPP S G +L +V PPV L
Sbjct: 304 RQEMRRQEPL-------PPPPPP-------SRGGNQLPRPPIVGGNKGRSGPLPPVPLGI 349
Query: 66 APPPAAPLLPGLPGWPAPSEPVLPLL----PLPSAPDSAAAAAAHPFPALHGQWLFGGHS 121
APPP P P PG P P P PLP P A P P G+
Sbjct: 350 APPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNG 409
Query: 122 PSLGLPPSSTVELVP 136
P+ PP LVP
Sbjct: 410 PA---PPPLPPALVP 421
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/94 (36%), Positives = 39/94 (41%), Gaps = 10/94 (10%)
Query: 22 RQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVL----LASAPPPAAPLLPGL 77
+Q L P A PPPPP +GL LS +PPV L PPP PL P
Sbjct: 641 QQKALPPPPASIPPPPPL------PSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPS 694
Query: 78 PGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPAL 111
P P P PL P+ P+ A P P L
Sbjct: 695 SAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGL 728
Score = 35.8 bits (81), Expect = 0.11
Identities = 26/67 (38%), Positives = 27/67 (40%), Gaps = 21/67 (31%)
Query: 33 PPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLP-----GWPAPSEPV 87
PPPPPP P SAG PP PPP P LP P G P P+ P
Sbjct: 682 PPPPPPPPLPPPSSAG----------PP------PPPPPPPLPNSPAPPNPGGPPPAPPP 725
Query: 88 LPLLPLP 94
L P P
Sbjct: 726 PGLAPPP 732
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/93 (39%), Positives = 43/93 (46%), Gaps = 13/93 (13%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAG-------VVVPPVLLASAP--PPAAPLLPGLP 78
P+ +PPPPP V AGL SAG PP LA P PP+ P P
Sbjct: 1269 PVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKP 1328
Query: 79 GWPAPSEPVL--PLLPLPSAPDSAAAAAAHPFP 109
P+P P L P P +A +AAAAAA P P
Sbjct: 1329 --PSPGAPALHVPAKPPRAAAAAAAAAAAPPAP 1359
Score = 44.7 bits (104), Expect = 2e-04
Identities = 76/288 (26%), Positives = 96/288 (33%), Gaps = 57/288 (19%)
Query: 1 MQAGARFQRRRRQLQQQQPR-----------RRQPLLWPMDAEPPPPPPWVWMVPGSAGL 49
++A A +RR R Q QQ +R+P +A P PPPP G+ +
Sbjct: 1118 VEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTV 1177
Query: 50 LRLSAGVVVPPVLLASAPPPAAPL---LPGLPGWPAPSEPVL-----PLLPLPSAPDSAA 101
R A P L PPPA P L LP P P P+ P P
Sbjct: 1178 RRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVP 1237
Query: 102 AAAAHPFPALHGQWLFGGHSPSL----GLPPSSTVELVPVFPHLCPSALATPIGKSWIDK 157
P P L G SP + G PP V P P P + G
Sbjct: 1238 KLQGSPTPTSKKVPLPGPGSPEVKRAHGTPP--PVSPKPPPPPTAPKPVKAVAG------ 1289
Query: 158 RIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVL 217
+P+ S P S A Q +L++P P + P
Sbjct: 1290 -LPS-----------GSAGPSPAPSP-----------ARQPPAALAKP-PGTPPSLGASP 1325
Query: 218 APQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGPSPSSVQ 265
A P PG +L V + P A A AAAAA P P S+ Q
Sbjct: 1326 AKPPSPGA--PALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQ 1371
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 45.8 bits (107), Expect = 1e-04
Identities = 61/219 (27%), Positives = 84/219 (38%), Gaps = 42/219 (19%)
Query: 64 ASAPPPAAPLLPGLPGWPA-PSEPVLPLLP-LPSAPDSAAAAAAHPFPALHGQWLFGGHS 121
A+ P PA P P LP P P +P LP P LP P P P L Q
Sbjct: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQ------- 989
Query: 122 PSLGLPPSSTVELVPVFPHLCPSAL--ATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHP 179
P L P+ V P+ PHL A ATP + + P +A+D
Sbjct: 990 PVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAP---------YAVD------ 1034
Query: 180 EESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVL--APQPIPGGCHNSLKVTSSPA 237
+ A V + A S PLP V+L AP+ +P +SL S+
Sbjct: 1035 -------------VAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQ-FPSSLATVSASV 1080
Query: 238 IAIATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIK 276
++ T A + +P GP +S P LT+ P++
Sbjct: 1081 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQ 1119
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 19/137 (13%)
Query: 23 QPLLWPMDAEPPPP--PPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGW 80
QP L P PP P PP + P R V+ P +L P P P P LP
Sbjct: 947 QPTLPPQPVLPPQPTLPPQPVLPPQPT---RPPQPVLPPQPMLP--PQPVLPPQPALPVR 1001
Query: 81 PAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVE------L 134
P P +P LP P+A + HP P P++ +PP++ + L
Sbjct: 1002 PEPLQPHLPEQAAPAATPGSQILLGHPAPYAVD---VAAQVPTVPVPPAAVLSPPLPEVL 1058
Query: 135 VPVFPHLC---PSALAT 148
+P P L PS+LAT
Sbjct: 1059 LPAAPELLPQFPSSLAT 1075
Score = 33.5 bits (75), Expect = 0.56
Identities = 31/94 (32%), Positives = 36/94 (38%), Gaps = 20/94 (21%)
Query: 59 PPVLLASAPPPAAPLLPGLPG-WPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLF 117
P + + S P PA P P L +P P+ P+LP PS P P P
Sbjct: 679 PGLPVGSVPAPACP--PSLQQHFPDPAMSFAPVLPPPSTP--MPTGPGQPAPP------- 727
Query: 118 GGHSPSLGLP--------PSSTVELVPVFPHLCP 143
G P L P P V L PV PHL P
Sbjct: 728 GQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPP 761
Score = 33.5 bits (75), Expect = 0.56
Identities = 42/145 (28%), Positives = 55/145 (37%), Gaps = 36/145 (24%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPL-------LPGLPGW 80
P PP PPP + S V++P LA+ PPA+P LP PG
Sbjct: 821 PTATVPPVPPPQYF-----------SPAVILPS--LAAPLPPASPALPLQAVKLPHPPGA 867
Query: 81 P--APSEPVLPLLP-----LPSAPDSAAAAAAHPFPA-LHGQWLFGGHSPSLG---LPPS 129
P P ++P P L AP AA + H A L GQ ++ P + +PPS
Sbjct: 868 PLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPS 927
Query: 130 -----STVELVPVFPHLCPSALATP 149
+ P P L P P
Sbjct: 928 PHHTVQNMRATPPQPALPPQPTLPP 952
Score = 33.1 bits (74), Expect = 0.73
Identities = 70/273 (25%), Positives = 101/273 (36%), Gaps = 64/273 (23%)
Query: 67 PPPAAPLLPGLPGWPAP-------------------SEPVLPLLPLPS------APDSAA 101
PPP+ P+ G PG PAP +PV+PL P+P AP S
Sbjct: 711 PPPSTPMPTG-PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQV 769
Query: 102 AAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPN 161
A A P Q P +PP + +PV P + P A G + +P+
Sbjct: 770 GAPAQLKPLQMPQ---APLQPLAQVPPQ--MPPIPVVPPITPLA-----GIDGLPPALPD 819
Query: 162 CKIFFNNSFALDSTWIHP-EESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVL--- 217
L + + P ++F P ++ +A L PA + PL V L
Sbjct: 820 ----------LPTATVPPVPPPQYF----SPAVILPSLAAPLP-PASPALPLQAVKLPHP 864
Query: 218 --APQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPI 275
AP +P + P +A+A AA+ S+ + P V P F +AP
Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAAL-SIHSAVAQLPG-QPVYPAAFPQMAPT 922
Query: 276 KIPLRTSP---VSDTRTERGRVARPPALMLRAQ 305
+P SP V + R + A PP L Q
Sbjct: 923 DVP--PSPHHTVQNMRATPPQPALPPQPTLPPQ 953
Score = 31.2 bits (69), Expect = 2.8
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 34 PPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPL 93
P P + P S L +SA V P A+ PPA P LPG PG +P P + L
Sbjct: 1060 PAAPELLPQFPSS--LATVSASVQSVPTQTATLLPPANPPLPGGPGIASPC-PTVQLTVE 1116
Query: 94 PSAPDSAA 101
P + A+
Sbjct: 1117 PVQEEQAS 1124
Score = 30.4 bits (67), Expect = 4.7
Identities = 30/97 (30%), Positives = 37/97 (38%), Gaps = 11/97 (11%)
Query: 54 AGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPS----APDSAAAAAAHPFP 109
A + V P+++ AP AP AP EP+ P P PS P A A P
Sbjct: 1442 APLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLP 1501
Query: 110 ALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSAL 146
A G + SL + L P P PSAL
Sbjct: 1502 AAVG-------AVSLATSQLPSPPLGPTVPPQPPSAL 1531
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 45.4 bits (106), Expect = 1e-04
Identities = 38/94 (40%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
Query: 12 RQLQQQQ----PRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVL-LASA 66
R L+QQ P PLL AEPPPPPP + S G L PP+ L +
Sbjct: 412 RALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPL--PSVGAKALPTAPPPPPLPGLGAM 469
Query: 67 PPPAAPLLPGLPG---WPAPSEPVLPLLPLPSAP 97
PPA PL P LPG + P P LP L P P
Sbjct: 470 APPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPP 503
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/77 (40%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 24 PLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAP 83
P L + A PP PP +PGS L PP+ PPP PLLPG+ GW P
Sbjct: 461 PPLPGLGAMAPPAPPLPPPLPGSCEFLPPPP----PPLPGLGCPPPPPPLLPGM-GW-GP 514
Query: 84 SEPVLPLLPLPSAPDSA 100
P PLLP +P A
Sbjct: 515 PPPPPPLLPCTCSPPVA 531
Score = 40.4 bits (93), Expect = 0.005
Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 23/102 (22%)
Query: 23 QPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPP----------VLLASAPPPAAP 72
QP A PPPPP ++PGS SA PP L +APPP P
Sbjct: 410 QPRALEQQASTPPPPPPPPLLPGS------SAEPPPPPPPPPLPSVGAKALPTAPPP--P 461
Query: 73 LLPGLPGWPAPSEPVLPLLP-----LPSAPDSAAAAAAHPFP 109
LPGL P+ P+ P LP LP P P P
Sbjct: 462 PLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPP 503
Score = 38.5 bits (88), Expect = 0.017
Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 4/104 (3%)
Query: 46 SAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAA 105
S +L++S + PPP PLLPG P P P PLPS + A A
Sbjct: 402 SESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPP---PPLPSV-GAKALPTA 457
Query: 106 HPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATP 149
P P L G +P L P + E +P P P P
Sbjct: 458 PPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPP 501
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 45.4 bits (106), Expect = 1e-04
Identities = 38/94 (40%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
Query: 12 RQLQQQQ----PRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVL-LASA 66
R L+QQ P PLL AEPPPPPP + S G L PP+ L +
Sbjct: 412 RALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPL--PSVGAKALPTAPPPPPLPGLGAM 469
Query: 67 PPPAAPLLPGLPG---WPAPSEPVLPLLPLPSAP 97
PPA PL P LPG + P P LP L P P
Sbjct: 470 APPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPP 503
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/77 (40%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 24 PLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAP 83
P L + A PP PP +PGS L PP+ PPP PLLPG+ GW P
Sbjct: 461 PPLPGLGAMAPPAPPLPPPLPGSCEFLPPPP----PPLPGLGCPPPPPPLLPGM-GW-GP 514
Query: 84 SEPVLPLLPLPSAPDSA 100
P PLLP +P A
Sbjct: 515 PPPPPPLLPCTCSPPVA 531
Score = 40.4 bits (93), Expect = 0.005
Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 23/102 (22%)
Query: 23 QPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPP----------VLLASAPPPAAP 72
QP A PPPPP ++PGS SA PP L +APPP P
Sbjct: 410 QPRALEQQASTPPPPPPPPLLPGS------SAEPPPPPPPPPLPSVGAKALPTAPPP--P 461
Query: 73 LLPGLPGWPAPSEPVLPLLP-----LPSAPDSAAAAAAHPFP 109
LPGL P+ P+ P LP LP P P P
Sbjct: 462 PLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPP 503
Score = 38.5 bits (88), Expect = 0.017
Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 4/104 (3%)
Query: 46 SAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAA 105
S +L++S + PPP PLLPG P P P PLPS + A A
Sbjct: 402 SESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPP---PPLPSV-GAKALPTA 457
Query: 106 HPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATP 149
P P L G +P L P + E +P P P P
Sbjct: 458 PPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPP 501
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 24/92 (26%)
Query: 7 FQRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASA 66
FQ++++Q QQQQ +++Q PPPPPP PP L
Sbjct: 17 FQQQQQQQQQQQQQQQQQQQQQQQPPPPPPPP--------------------PPPQLPQP 56
Query: 67 PPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPD 98
PP A PLLP P P P P P P+ +
Sbjct: 57 PPQAQPLLP----QPQPPPPPPPPPPGPAVAE 84
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 13/80 (16%)
Query: 8 QRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAP 67
Q++++Q QQQQ +++Q P PPPPPP + P A P+L P
Sbjct: 21 QQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQPPPQA-----------QPLLPQPQP 69
Query: 68 PPAAPLLPGLPGWPAPSEPV 87
PP P P PG EP+
Sbjct: 70 PPPPP--PPPPGPAVAEEPL 87
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/240 (26%), Positives = 88/240 (36%), Gaps = 50/240 (20%)
Query: 19 PRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLP 78
P+ PL P PP PP M P + R+ + PP+ + +PP + P+ P L
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP-LA 782
Query: 79 GWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVF 138
P + P L PL + P A+ FP GQ F SPS LP S +
Sbjct: 783 KPPPQAPPALATPPLQALPSPPAS-----FP---GQAPF---SPSASLPMSP----LATP 827
Query: 139 PHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPRLLANQV 198
P P LA P+ ++P P S +P
Sbjct: 828 PPQAPPVLAAPL------LQVPP----------------SPPASPTLQAPRRPPTPGPDT 865
Query: 199 AVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRG 258
+V S P T+ LAP P P + S P +A +++A + PE LRG
Sbjct: 866 SV--------SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS----TPEELRG 913
Score = 41.2 bits (95), Expect = 0.003
Identities = 78/294 (26%), Positives = 97/294 (32%), Gaps = 42/294 (14%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRL-SAGVVVPPVLLASAPPPAAPLLPGLPGWPAP--- 83
P++ + PP + P S L + + PP L ++ P P L P PAP
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE-TPPCPAPCPL 569
Query: 84 SEPVLPL-LPLPSAPDSAAAAAAHPFPALHGQWLFGGHS--------------PSLGLPP 128
P PL P P P S A PAL L G S P L LPP
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629
Query: 129 SSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGH 188
P P L P LATP + PN P ++ F
Sbjct: 630 LQAPPSPPASPPLSP--LATP------SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 189 EKPRLLANQVAVSLSRP--APASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAA 246
P V+ S + P AP S P + + P P P S T P AA
Sbjct: 682 SPP------VSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPP 734
Query: 247 AMVSVDPENLRGPSPSSVQPRHF--LTLAPIKIPLRTSPVSDTRTERGRVARPP 298
V P SPS+ P L AP PL+ P +A+PP
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAP---PLQVPPSPPASLPMSPLAKPP 785
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/132 (30%), Positives = 48/132 (36%), Gaps = 22/132 (16%)
Query: 24 PLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAP-----LLPGLP 78
P L P+ PP PP + + P L + PP+ + P P AP L P
Sbjct: 609 PPLSPLATPPPQAPPXLALPP----LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664
Query: 79 GWPAPSEPV-LPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPV 137
P PS PV P P S P S +A P PSL PP P
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAP------------PSLAAPPLQVPPSPPA 712
Query: 138 FPHLCPSALATP 149
P + PSA P
Sbjct: 713 SPPMSPSATPPP 724
Score = 31.6 bits (70), Expect = 2.1
Identities = 76/340 (22%), Positives = 99/340 (29%), Gaps = 67/340 (19%)
Query: 64 ASAPPPAAP--LLPGLPGWPAPSEPVLPLL-------------PLPSAPDSAAAAAAHPF 108
A P AP L P PG P P PV P PL A
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 109 PALHGQWLFGGHS---PSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIP----N 161
G G S P+ P S E P + P +++P S + P
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 162 CKIFFNNSFALDSTWIHPEESRFFHGHEKP---------------RLLANQVAVSLSRPA 206
+I + A P+ S G + R A V L RPA
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 207 PASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENL---------- 256
P++RP P P+ SPA +A + +L
Sbjct: 194 PSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 257 --RGPS----------PSSVQPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPALMLRA 304
GPS PS +P+ L P P T P D G ++ P A
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRP---PQVTPPRKDAAPALGPLSSSPL----A 305
Query: 305 QKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSP 344
S G K PPP P +TP+P +P
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
Score = 30.4 bits (67), Expect = 4.7
Identities = 29/102 (28%), Positives = 35/102 (34%), Gaps = 22/102 (21%)
Query: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPV 87
P+ A PP PP +P + PP + + PP+ LP P P P
Sbjct: 326 PLPATLPPSPPLATPLP------------LAPP---SPSAPPSLQTLPSPPATPPSQAPP 370
Query: 88 LPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPS 129
P AP S P H SPSL PPS
Sbjct: 371 SMTTPPMQAPPSLQTIP--PIQVPHSL-----TSPSLQAPPS 405
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/118 (32%), Positives = 43/118 (36%), Gaps = 19/118 (16%)
Query: 23 QPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPA 82
QP L P+ PPPP P PG PP PPP P P PG
Sbjct: 286 QPPLGPLPPGPPPPVPGYGPPPG-------------PPPPQQGPPPPPGPFPPRPPG--- 329
Query: 83 PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPH 140
P P L L P P P A P PA H F + G+P S + P P+
Sbjct: 330 PLGPPLTLAPPPHLPGPPPGA---PPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPY 384
Score = 37.7 bits (86), Expect = 0.030
Identities = 42/133 (31%), Positives = 47/133 (35%), Gaps = 10/133 (7%)
Query: 22 RQPLLWPMDAEPP-PPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGW 80
R PL P PP PPPP + P AG + G PP +L P P L LP
Sbjct: 238 RPPLGPPGPPGPPGPPPPGQVLPPPLAG--PPNRGDRPPPPVLFPGQPFGQPPLGPLPPG 295
Query: 81 PAPSEPVLPLLPLPSAPDSAAAAAAHPFPALH----GQWLFGGHSPSLGLPPSSTVELVP 136
P P P P P P PFP G L P L PP P
Sbjct: 296 PPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGA---PP 352
Query: 137 VFPHLCPSALATP 149
PH+ P+ P
Sbjct: 353 PAPHVNPAFFPPP 365
Score = 30.4 bits (67), Expect = 4.7
Identities = 31/74 (41%), Positives = 32/74 (43%), Gaps = 10/74 (13%)
Query: 59 PPVLLASAPPPAAPL-LPGLPGWPAPSEP--VLPLLPLPSAPDSAAAAAAHPFPALHGQW 115
PP A PP PL PG PG P P P VLP PL P+ P P L
Sbjct: 227 PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLP-PPLAGPPNRGDRP---PPPVLFPGQ 282
Query: 116 LFGGHSPSLG-LPP 128
FG P LG LPP
Sbjct: 283 PFG--QPPLGPLPP 294
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 44.7 bits (104), Expect = 2e-04
Identities = 81/328 (24%), Positives = 106/328 (32%), Gaps = 71/328 (21%)
Query: 10 RRRQLQQQQPRRRQPL-LWPMDAEPPP---------PPPWVWMVPGSAGLLRLSAG---- 55
+++ LQ Q P + P + P + PP P P VP A
Sbjct: 176 QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ 235
Query: 56 ---VVVPPVLLASAPP--PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPA 110
VP + AP P P P P P+P P+ PL P +A +H P
Sbjct: 236 APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP----SAPSHAQPP 291
Query: 111 LHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSF 170
LHGQ G HS G P+ H P P G +P
Sbjct: 292 LHGQGPPGPHSLQAG----------PLLQHPGP---PQPFG-------LPPQASQGQAPL 331
Query: 171 ALDSTWIHPEESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSL 230
+P H +L A+Q A+ +P P +PLP LA I
Sbjct: 332 GTSPAAAYP--------HTSLQLPASQSALQSQQP-PREQPLPPAPLAMPHI-------- 374
Query: 231 KVTSSPAIAIATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTE 290
P A P +L GPSP S+ A + P P+S T
Sbjct: 375 ---KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN-------ANLPPPPALKPLSSLSTH 424
Query: 291 RGRVARPPALMLRAQKSRDGDKEDKEPP 318
A PP L L Q S+ +PP
Sbjct: 425 HPPSAHPPPLQLMPQ-SQPLPSSPAQPP 451
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/165 (30%), Positives = 59/165 (35%), Gaps = 37/165 (22%)
Query: 14 LQQQQPRRRQPL----LWPMDAEPPP-------PPPWVWMVP---GSAGLLRLSAGVVVP 59
LQ QQP R QPL L +PPP P P P ++A + P
Sbjct: 353 LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP 412
Query: 60 PVLL----------ASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFP 109
P L SA PP L+P P PS P P L + + A+HP
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMP--QSQPLPSSPAQP-PGLTQSQNLPPPPASHPPT 469
Query: 110 ALH---GQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIG 151
LH Q F H G PP P+ P CPS P G
Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPP-------PITPPTCPSTSTPPAG 507
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 44.7 bits (104), Expect = 2e-04
Identities = 81/328 (24%), Positives = 106/328 (32%), Gaps = 71/328 (21%)
Query: 10 RRRQLQQQQPRRRQPL-LWPMDAEPPP---------PPPWVWMVPGSAGLLRLSAG---- 55
+++ LQ Q P + P + P + PP P P VP A
Sbjct: 730 QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ 789
Query: 56 ---VVVPPVLLASAPP--PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPA 110
VP + AP P P P P P+P P+ PL P +A +H P
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP----SAPSHAQPP 845
Query: 111 LHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSF 170
LHGQ G HS G P+ H P P G +P
Sbjct: 846 LHGQGPPGPHSLQAG----------PLLQHPGP---PQPFG-------LPPQASQGQAPL 885
Query: 171 ALDSTWIHPEESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSL 230
+P H +L A+Q A+ +P P +PLP LA I
Sbjct: 886 GTSPAAAYP--------HTSLQLPASQSALQSQQP-PREQPLPPAPLAMPHI-------- 928
Query: 231 KVTSSPAIAIATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTE 290
P A P +L GPSP S+ A + P P+S T
Sbjct: 929 ---KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN-------ANLPPPPALKPLSSLSTH 978
Query: 291 RGRVARPPALMLRAQKSRDGDKEDKEPP 318
A PP L L Q S+ +PP
Sbjct: 979 HPPSAHPPPLQLMPQ-SQPLPSSPAQPP 1005
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/165 (30%), Positives = 59/165 (35%), Gaps = 37/165 (22%)
Query: 14 LQQQQPRRRQPL----LWPMDAEPPP-------PPPWVWMVP---GSAGLLRLSAGVVVP 59
LQ QQP R QPL L +PPP P P P ++A + P
Sbjct: 907 LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP 966
Query: 60 PVLL----------ASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFP 109
P L SA PP L+P P PS P P L + + A+HP
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMP--QSQPLPSSPAQP-PGLTQSQNLPPPPASHPPT 1023
Query: 110 ALH---GQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIG 151
LH Q F H G PP P+ P CPS P G
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPP-------PITPPTCPSTSTPPAG 1061
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 44.7 bits (104), Expect = 2e-04
Identities = 81/328 (24%), Positives = 106/328 (32%), Gaps = 71/328 (21%)
Query: 10 RRRQLQQQQPRRRQPL-LWPMDAEPPP---------PPPWVWMVPGSAGLLRLSAG---- 55
+++ LQ Q P + P + P + PP P P VP A
Sbjct: 730 QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ 789
Query: 56 ---VVVPPVLLASAPP--PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPA 110
VP + AP P P P P P+P P+ PL P +A +H P
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP----SAPSHAQPP 845
Query: 111 LHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSF 170
LHGQ G HS G P+ H P P G +P
Sbjct: 846 LHGQGPPGPHSLQAG----------PLLQHPGP---PQPFG-------LPPQASQGQAPL 885
Query: 171 ALDSTWIHPEESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSL 230
+P H +L A+Q A+ +P P +PLP LA I
Sbjct: 886 GTSPAAAYP--------HTSLQLPASQSALQSQQP-PREQPLPPAPLAMPHI-------- 928
Query: 231 KVTSSPAIAIATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTE 290
P A P +L GPSP S+ A + P P+S T
Sbjct: 929 ---KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN-------ANLPPPPALKPLSSLSTH 978
Query: 291 RGRVARPPALMLRAQKSRDGDKEDKEPP 318
A PP L L Q S+ +PP
Sbjct: 979 HPPSAHPPPLQLMPQ-SQPLPSSPAQPP 1005
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/165 (30%), Positives = 59/165 (35%), Gaps = 37/165 (22%)
Query: 14 LQQQQPRRRQPL----LWPMDAEPPP-------PPPWVWMVP---GSAGLLRLSAGVVVP 59
LQ QQP R QPL L +PPP P P P ++A + P
Sbjct: 907 LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP 966
Query: 60 PVLL----------ASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFP 109
P L SA PP L+P P PS P P L + + A+HP
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMP--QSQPLPSSPAQP-PGLTQSQNLPPPPASHPPT 1023
Query: 110 ALH---GQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIG 151
LH Q F H G PP P+ P CPS P G
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPP-------PITPPTCPSTSTPPAG 1061
>gi|47825361 non-specific cytotoxic cell receptor protein 1 homolog
[Homo sapiens]
Length = 275
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Query: 58 VPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLF 117
+PP + +PPP+ P LP P P+P+ P P LP P+ P + AH L +W
Sbjct: 25 LPPSPRSPSPPPSPPPLPSPPSLPSPAAPEAPELPEPAQP-----SEAHARQLLLEEW-- 77
Query: 118 GGHSPSLGLPPSSTVELVPVFPHLCPSALATP 149
G S L LP T +L+ + L + L +P
Sbjct: 78 GPLSGGLELPQRLTWKLLLLRRPLYRNLLRSP 109
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 43.5 bits (101), Expect = 5e-04
Identities = 45/149 (30%), Positives = 57/149 (38%), Gaps = 30/149 (20%)
Query: 17 QQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPL-LP 75
Q P + ++ PPPPPP + S LR S PP + PPPA L P
Sbjct: 309 QSPATGRTPVFVSPTPPPPPPPLPSAL--STSSLRASMTSTPPPPVPPPPPPPATALQAP 366
Query: 76 GLPGWPAPSE-----------PVLPLLPLPSAPDSAAA-----AAAHPFPALHGQWLFGG 119
+P PAP + P+ P L PS P + AA HP P Q
Sbjct: 367 AVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQ----- 421
Query: 120 HSPSLGLPPSSTVELVPVFPHLCPSALAT 148
GLPP +P P + PS+ T
Sbjct: 422 -----GLPPPPPPPPLPP-PGIRPSSPVT 444
Score = 42.4 bits (98), Expect = 0.001
Identities = 63/286 (22%), Positives = 95/286 (33%), Gaps = 57/286 (19%)
Query: 32 EPPPPPPW---------VWMVPGSAGLLR---LSAGVVVPPVLLASAPPPAAPLLPGLPG 79
EPPPPPP + + GL+ S PV ++ PPP P LP
Sbjct: 277 EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALS 336
Query: 80 WPA-----PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVEL 134
+ S P P+ P P P +A A A P PP + +++
Sbjct: 337 TSSLRASMTSTPPPPVPPPPPPPATALQAPAVP-------------------PPPAPLQI 377
Query: 135 VPVFPHLCPSALATPIGKSW--IDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPR 192
P H P +A P+ + + + P C ++ +HP G P
Sbjct: 378 APGVLHPAPPPIAPPLVQPSPPVARAAPVC----------ETVPVHPLPQGEVQGLPPP- 426
Query: 193 LLANQVAVSLSRPAPASRP-LPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSV 251
P P RP P V A P G H + P + + + + V
Sbjct: 427 ------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
Query: 252 DPENLRGPSPSSV-QPRHFLTLAPIKIPLRTSPVSDTRTERGRVAR 296
E R PS V + L I+ ++ V + R + + R
Sbjct: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHER 526
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 43.5 bits (101), Expect = 5e-04
Identities = 45/149 (30%), Positives = 57/149 (38%), Gaps = 30/149 (20%)
Query: 17 QQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPL-LP 75
Q P + ++ PPPPPP + S LR S PP + PPPA L P
Sbjct: 309 QSPATGRTPVFVSPTPPPPPPPLPSAL--STSSLRASMTSTPPPPVPPPPPPPATALQAP 366
Query: 76 GLPGWPAPSE-----------PVLPLLPLPSAPDSAAA-----AAAHPFPALHGQWLFGG 119
+P PAP + P+ P L PS P + AA HP P Q
Sbjct: 367 AVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQ----- 421
Query: 120 HSPSLGLPPSSTVELVPVFPHLCPSALAT 148
GLPP +P P + PS+ T
Sbjct: 422 -----GLPPPPPPPPLPP-PGIRPSSPVT 444
Score = 42.4 bits (98), Expect = 0.001
Identities = 63/286 (22%), Positives = 95/286 (33%), Gaps = 57/286 (19%)
Query: 32 EPPPPPPW---------VWMVPGSAGLLR---LSAGVVVPPVLLASAPPPAAPLLPGLPG 79
EPPPPPP + + GL+ S PV ++ PPP P LP
Sbjct: 277 EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALS 336
Query: 80 WPA-----PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVEL 134
+ S P P+ P P P +A A A P PP + +++
Sbjct: 337 TSSLRASMTSTPPPPVPPPPPPPATALQAPAVP-------------------PPPAPLQI 377
Query: 135 VPVFPHLCPSALATPIGKSW--IDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPR 192
P H P +A P+ + + + P C ++ +HP G P
Sbjct: 378 APGVLHPAPPPIAPPLVQPSPPVARAAPVC----------ETVPVHPLPQGEVQGLPPP- 426
Query: 193 LLANQVAVSLSRPAPASRP-LPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSV 251
P P RP P V A P G H + P + + + + V
Sbjct: 427 ------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
Query: 252 DPENLRGPSPSSV-QPRHFLTLAPIKIPLRTSPVSDTRTERGRVAR 296
E R PS V + L I+ ++ V + R + + R
Sbjct: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHER 526
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 43.5 bits (101), Expect = 5e-04
Identities = 45/149 (30%), Positives = 57/149 (38%), Gaps = 30/149 (20%)
Query: 17 QQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPL-LP 75
Q P + ++ PPPPPP + S LR S PP + PPPA L P
Sbjct: 309 QSPATGRTPVFVSPTPPPPPPPLPSAL--STSSLRASMTSTPPPPVPPPPPPPATALQAP 366
Query: 76 GLPGWPAPSE-----------PVLPLLPLPSAPDSAAA-----AAAHPFPALHGQWLFGG 119
+P PAP + P+ P L PS P + AA HP P Q
Sbjct: 367 AVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQ----- 421
Query: 120 HSPSLGLPPSSTVELVPVFPHLCPSALAT 148
GLPP +P P + PS+ T
Sbjct: 422 -----GLPPPPPPPPLPP-PGIRPSSPVT 444
Score = 42.4 bits (98), Expect = 0.001
Identities = 63/286 (22%), Positives = 95/286 (33%), Gaps = 57/286 (19%)
Query: 32 EPPPPPPW---------VWMVPGSAGLLR---LSAGVVVPPVLLASAPPPAAPLLPGLPG 79
EPPPPPP + + GL+ S PV ++ PPP P LP
Sbjct: 277 EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALS 336
Query: 80 WPA-----PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVEL 134
+ S P P+ P P P +A A A P PP + +++
Sbjct: 337 TSSLRASMTSTPPPPVPPPPPPPATALQAPAVP-------------------PPPAPLQI 377
Query: 135 VPVFPHLCPSALATPIGKSW--IDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPR 192
P H P +A P+ + + + P C ++ +HP G P
Sbjct: 378 APGVLHPAPPPIAPPLVQPSPPVARAAPVC----------ETVPVHPLPQGEVQGLPPP- 426
Query: 193 LLANQVAVSLSRPAPASRP-LPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSV 251
P P RP P V A P G H + P + + + + V
Sbjct: 427 ------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
Query: 252 DPENLRGPSPSSV-QPRHFLTLAPIKIPLRTSPVSDTRTERGRVAR 296
E R PS V + L I+ ++ V + R + + R
Sbjct: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHER 526
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,859,238
Number of Sequences: 37866
Number of extensions: 1894546
Number of successful extensions: 18854
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 694
Number of HSP's that attempted gapping in prelim test: 13615
Number of HSP's gapped (non-prelim): 4260
length of query: 586
length of database: 18,247,518
effective HSP length: 108
effective length of query: 478
effective length of database: 14,157,990
effective search space: 6767519220
effective search space used: 6767519220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.