Guide to the Human Genome
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Search of human proteins with 148612890

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148612890 serine-arginine repressor protein [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148612890 serine-arginine repressor protein [Homo sapiens]         532   e-151
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso...   241   4e-64
gi|5730079 FUS interacting protein (serine-arginine rich) 1 isof...   218   3e-57
gi|169161980 PREDICTED: similar to FUS interacting protein (seri...   214   6e-56
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]    127   7e-30
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]   121   7e-28
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]    114   9e-26
gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens]      95   5e-20
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      87   1e-17
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]     85   6e-17
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]     85   6e-17
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     82   4e-16
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          73   2e-13
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        71   8e-13
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    70   2e-12
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]     69   3e-12
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           68   9e-12
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           68   9e-12
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     67   2e-11
gi|9558733 transformer-2 alpha [Homo sapiens]                          66   3e-11
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]         66   3e-11
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    65   5e-11
gi|52426743 cisplatin resistance-associated overexpressed protei...    64   2e-10
gi|19923485 cisplatin resistance-associated overexpressed protei...    64   2e-10
gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa...    63   2e-10
gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap...    63   2e-10
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H...    63   3e-10
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom...    63   3e-10
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           63   3e-10
gi|117676384 splicing factor, arginine/serine-rich 2, interactin...    62   5e-10

>gi|148612890 serine-arginine repressor protein [Homo sapiens]
          Length = 261

 Score =  532 bits (1371), Expect = e-151
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60
           MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED
Sbjct: 1   MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60

Query: 61  VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRT 120
           VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRT
Sbjct: 61  VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRT 120

Query: 121 RSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRS 180
           RSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRS
Sbjct: 121 RSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRS 180

Query: 181 RSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT 240
           RSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT
Sbjct: 181 RSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT 240

Query: 241 AKHSHFRSHSRSRSYRHKNSW 261
           AKHSHFRSHSRSRSYRHKNSW
Sbjct: 241 AKHSHFRSHSRSRSYRHKNSW 261


>gi|16905517 FUS interacting protein (serine-arginine rich) 1
           isoform 2 [Homo sapiens]
          Length = 262

 Score =  241 bits (616), Expect = 4e-64
 Identities = 151/276 (54%), Positives = 172/276 (62%), Gaps = 37/276 (13%)

Query: 1   MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60
           MSRY RPPNTSLF+RNVAD TR EDLRREFGRYGPIVDVY+PLDFYTRRPRGFAYVQFED
Sbjct: 1   MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60

Query: 61  VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPS------DHRRSR 113
           VRDAEDAL+NL+RKW+CGRQIEIQFAQGDRKTP QMK+KE R+  S S       +RRSR
Sbjct: 61  VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120

Query: 114 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN 173
           S S  R RSRS S+  N RR            SYS   SR    PRRS    +S +    
Sbjct: 121 SRSYERRRSRSRSFDYNYRR------------SYSPRNSRPTGRPRRS----RSHSDNDR 164

Query: 174 FGSRGRSRSKSLQKRSKSIGKSQS-SSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYT 232
           F  R RS S     RSKS  +S+S S P+K+  + ++SRS   H+ +   S   S   Y 
Sbjct: 165 FKHRNRSFS-----RSKSNSRSRSKSQPKKEMKAKSRSRS-ASHTKTRGTSKTDSKTHYK 218

Query: 233 N-------SETKVQTAKHSHFRSHSRSRSYRHKNSW 261
           +       S  K      S  RS SRSRS     SW
Sbjct: 219 SGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSW 254



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 95  QMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRS 154
           +MK+K R     + H ++R  S+  +++   S  R  + S   +  R +  S SQS+SRS
Sbjct: 190 EMKAKSRS--RSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRS 247

Query: 155 KSLPRRSTSARQS 167
           KS  R  TS + S
Sbjct: 248 KSRSRSWTSPKSS 260


>gi|5730079 FUS interacting protein (serine-arginine rich) 1 isoform
           1 [Homo sapiens]
          Length = 183

 Score =  218 bits (556), Expect = 3e-57
 Identities = 119/184 (64%), Positives = 133/184 (72%), Gaps = 19/184 (10%)

Query: 1   MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60
           MSRY RPPNTSLF+RNVAD TR EDLRREFGRYGPIVDVY+PLDFYTRRPRGFAYVQFED
Sbjct: 1   MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60

Query: 61  VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPS------DHRRSR 113
           VRDAEDAL+NL+RKW+CGRQIEIQFAQGDRKTP QMK+KE R+  S S       +RRSR
Sbjct: 61  VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120

Query: 114 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN 173
           S S  R RSRS S+  N RR            SYS   SR    PRRS S   +  P  +
Sbjct: 121 SRSYERRRSRSRSFDYNYRR------------SYSPRNSRPTGRPRRSRSHSDNDRPNCS 168

Query: 174 FGSR 177
           + ++
Sbjct: 169 WNTQ 172


>gi|169161980 PREDICTED: similar to FUS interacting protein
           (serine-arginine rich) 1, partial [Homo sapiens]
          Length = 181

 Score =  214 bits (545), Expect = 6e-56
 Identities = 117/184 (63%), Positives = 133/184 (72%), Gaps = 20/184 (10%)

Query: 1   MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60
           MSRY RPPNTSLF+RNVAD TR EDLRREFGRYGPIVDVY+PLDFYTRRPRGFAYVQFED
Sbjct: 1   MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60

Query: 61  VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPS------DHRRSR 113
           VRDAEDAL+NL+RKW+CGRQIEIQFAQGDRKTP QMK+KE R+  S S       +RRSR
Sbjct: 61  VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120

Query: 114 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN 173
           S S  R RSRS S+  N RRS S              ++R    PRRS S   +  P  +
Sbjct: 121 SRSYERRRSRSRSFDYNYRRSYS-------------PRNRPTGRPRRSRSHSDNDRPNCS 167

Query: 174 FGSR 177
           + ++
Sbjct: 168 WNTQ 171


>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
          Length = 221

 Score =  127 bits (320), Expect = 7e-30
 Identities = 94/237 (39%), Positives = 131/237 (55%), Gaps = 36/237 (15%)

Query: 4   YTRPPN-----TSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQF 58
           Y RPP      TSL + N+   T P+ LRR F +YG + DVYIP D YT+  RGFA+V+F
Sbjct: 3   YGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62

Query: 59  EDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDH------RRS 112
            D RDAEDA+  ++   + GR++ +Q A+  R  P       R P  P  +      RRS
Sbjct: 63  HDKRDAEDAMDAMDGAVLDGRELRVQMARYGR--PPDSHHSRRGP-PPRRYGGGGYGRRS 119

Query: 113 RSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRR 172
           RSP +RR RSRS S  R+R RS S       R+S S+S+SR++S  R ++ +R +R  + 
Sbjct: 120 RSP-RRRRRSRSRSRSRSRSRSRS-------RYSRSKSRSRTRSRSRSTSKSRSARRSKS 171

Query: 173 NFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPK 229
              S  RSRS     RS+S  +S+S  P  +  S ++SRS         +SP KSP+
Sbjct: 172 KSSSVSRSRS-----RSRSRSRSRSPPPVSKRESKSRSRS---------KSPPKSPE 214


>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
          Length = 282

 Score =  121 bits (303), Expect = 7e-28
 Identities = 97/265 (36%), Positives = 139/265 (52%), Gaps = 21/265 (7%)

Query: 11  SLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYN 70
           +L + N+   T P+ LRR F +YG + DVYIP + +T+ PRGFA+V+F D RDA+DA   
Sbjct: 15  TLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAA 74

Query: 71  LNRKWVCGRQIEIQFAQ-GDRKTPGQMKSKERHPC--------SPSDHRRSRSPSQR-RT 120
           ++   + GR++ +Q A+ G R  P   + + R           S S  RRSRSP +R R+
Sbjct: 75  MDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRS 134

Query: 121 RSRSSSWGRNRRRSDSLKESRHRRFSYSQ---SKSRSKSLPRRSTSARQSRTPRRNFGSR 177
           RSR  S  R+R RS   + SR+ R  YS+   S+SR    P   +  R+SR    ++ S 
Sbjct: 135 RSRGPSCSRSRSRS-RYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSS 193

Query: 178 GRSRSK-SLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKS-PKGYTNSE 235
           G S S+ S    S+S  KS SS+  +  S+   S +    S S++RS  +S     T S 
Sbjct: 194 GYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSP 253

Query: 236 TKVQTAKHSHFRSHSRSRSYRHKNS 260
            +V   K     S SRSRS R   S
Sbjct: 254 PRVSKRK-----SKSRSRSKRPPKS 273


>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
          Length = 238

 Score =  114 bits (285), Expect = 9e-26
 Identities = 92/237 (38%), Positives = 124/237 (52%), Gaps = 31/237 (13%)

Query: 1   MSRYTR-PPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFE 59
           MSRY R    T +++ N+       +L R F  YGP+  V+I      R P GFA+V+FE
Sbjct: 1   MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFE 55

Query: 60  DVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSD----------- 108
           D RDAEDA+  L+ K +CG ++ ++ + G  +     +   R P  P+D           
Sbjct: 56  DPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHY 115

Query: 109 ----HRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRF-SYSQSKSRSKSLPR-RST 162
               HR SR   + R+RSRS S  R RR S S   SR RR  S S  +SRS SL R RS 
Sbjct: 116 AYDCHRYSRR-RRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSA 174

Query: 163 SARQSRT----PRRNF--GSRGRSRSKSLQKRSKSIGKSQSSSPQKQTS-SGTKSRS 212
           S R+SR+      R F   SR RSRS+S+ +   S  KS+S SP++  S SG+  RS
Sbjct: 175 SLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRS 231


>gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens]
          Length = 164

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 60/171 (35%), Positives = 97/171 (56%), Gaps = 18/171 (10%)

Query: 1   MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60
           M R + P +  +++ N+ +     +L R FG YGP+  V++      R P GFA+V+FED
Sbjct: 1   MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED 55

Query: 61  VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTP--GQMKSKERHPCSPSDHRRSRSPSQR 118
            RDA DA+  L+ + +CG ++ ++ + G++++   G   S  R P    D+RR   P +R
Sbjct: 56  PRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRP--RDDYRRRSPPPRR 113

Query: 119 RT-------RSRSSSWGRNRRRSDSLKESRHRR--FSYSQSKSRSKSLPRR 160
           R+       RSRS S  R+RRR  SL   R+ +   S+S+S+SRS+S  R+
Sbjct: 114 RSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK 164


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 71/209 (33%), Positives = 103/209 (49%), Gaps = 23/209 (11%)

Query: 56  VQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSP 115
           ++F    D + AL  L+   + GR I +            ++ K R     + HRRS S 
Sbjct: 151 IEFRSYSDMKRALDKLDGTEINGRNIRL------------IEDKPR-----TSHRRSYSG 193

Query: 116 SQRRTRSRSSSWGRNRR----RSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPR 171
           S+ R+RSR  S  R+RR    RS S+ +SR R  S S+ +SRS+S  R+S S  +S+ P+
Sbjct: 194 SRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSK-PK 252

Query: 172 RNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGY 231
            + GS   SRS+S  +  KS  +S+S SP++      KS+S  R S S + SP   P   
Sbjct: 253 SDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSR-SQSRSNSPLPVPPSK 311

Query: 232 TNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
             S +       S  RS SRS+S     S
Sbjct: 312 ARSVSPPPKRATSRSRSRSRSKSRSRSRS 340



 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 80/290 (27%), Positives = 128/290 (44%), Gaps = 60/290 (20%)

Query: 12  LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
           ++I  ++   R +D++R F  YG +++V +          G+ +V+FED RDA+DA+Y L
Sbjct: 4   VYIGRLSYNVREKDIQRFFSGYGRLLEVDLK--------NGYGFVEFEDSRDADDAVYEL 55

Query: 72  NRKWVCGRQIEIQFAQGDRK-----TPGQMKSKERHPCSPSDHRRSRSPSQR-------R 119
           N K +CG ++ ++ A+G R+     + G       +    +  R    P  R        
Sbjct: 56  NGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVE 115

Query: 120 TRSRSSSW-----------------GRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRST 162
             S   SW                     R ++ + E R    SYS  K     L     
Sbjct: 116 NLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFR----SYSDMKRALDKLDGTEI 171

Query: 163 SARQSR--------TPRRNF-GSRGRSRS---------KSLQKRSKSIGKSQSSSPQKQT 204
           + R  R        + RR++ GSR RSRS         +S + RS+SI KS+S S + ++
Sbjct: 172 NGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRS-RSRS 230

Query: 205 SSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
              ++SRS GR S S ++S  KS +G  +        ++   RS SRSRS
Sbjct: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 27/103 (26%)

Query: 90  RKTPGQMKSKERHPCSPSDHRRSRSPSQ---RRTRSRSSSWGRN-----RRRSDSLKESR 141
           RK+  + KSK +       H RSRS  +    R+RSRS S   N     + +S S  +SR
Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR 300

Query: 142 H-------------------RRFSYSQSKSRSKSLPRRSTSAR 165
                               R  S S+S+SRSKS  R  +S+R
Sbjct: 301 SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343


>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 85.1 bits (209), Expect = 6e-17
 Identities = 84/272 (30%), Positives = 130/272 (47%), Gaps = 41/272 (15%)

Query: 12  LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
           +FI  +  A R +D+ R F  YG I D+ +         RGF +V+FED RDA+DA+Y L
Sbjct: 6   VFIGRLNPAAREKDVERFFKGYGRIRDIDLK--------RGFGFVEFEDPRDADDAVYEL 57

Query: 72  NRKWVCGRQIEIQFAQG-DRKTPGQMKSKERHPC-SPSDHRRSRSPSQRRTR------SR 123
           + K +C  ++ I+ A+   R   G+ +  +R     P + RR+  P +   R      S 
Sbjct: 58  DGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSS 117

Query: 124 SSSW----GRNRRRSDSLKESRHRR---------FSYSQSKSRSKSLPRRSTSARQSRT- 169
             SW       R+  +      HR           SY   K+  + L  +  + R+ +  
Sbjct: 118 RVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLI 177

Query: 170 --PRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGR---HSDSIARSP 224
              +R+  SR RSRS++   RS S  +S+S S  +++ S ++SRS  R    S S++RSP
Sbjct: 178 EGSKRHSRSRSRSRSRT---RSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234

Query: 225 C--KSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
              KS K  ++S +K   A     RS SRSRS
Sbjct: 235 VPEKSQKRGSSSRSK-SPASVDRQRSRSRSRS 265



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 53/164 (32%), Positives = 76/164 (46%), Gaps = 42/164 (25%)

Query: 56  VQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSP 115
           V+F    D ++A+  L+ K + GR+I++            ++  +RH         SRS 
Sbjct: 149 VEFASYGDLKNAIEKLSGKEINGRKIKL------------IEGSKRH---------SRSR 187

Query: 116 SQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFG 175
           S+ R+R+RSSS  R+R RS S K       SYS+S+SRS+S  R                
Sbjct: 188 SRSRSRTRSSSRSRSRSRSRSRK-------SYSRSRSRSRSRSRSK-------------- 226

Query: 176 SRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDS 219
           SR  SRS   +K  K    S+S SP       ++SRS  R  DS
Sbjct: 227 SRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDS 270


>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 85.1 bits (209), Expect = 6e-17
 Identities = 84/272 (30%), Positives = 130/272 (47%), Gaps = 41/272 (15%)

Query: 12  LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
           +FI  +  A R +D+ R F  YG I D+ +         RGF +V+FED RDA+DA+Y L
Sbjct: 6   VFIGRLNPAAREKDVERFFKGYGRIRDIDLK--------RGFGFVEFEDPRDADDAVYEL 57

Query: 72  NRKWVCGRQIEIQFAQG-DRKTPGQMKSKERHPC-SPSDHRRSRSPSQRRTR------SR 123
           + K +C  ++ I+ A+   R   G+ +  +R     P + RR+  P +   R      S 
Sbjct: 58  DGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSS 117

Query: 124 SSSW----GRNRRRSDSLKESRHRR---------FSYSQSKSRSKSLPRRSTSARQSRT- 169
             SW       R+  +      HR           SY   K+  + L  +  + R+ +  
Sbjct: 118 RVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLI 177

Query: 170 --PRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGR---HSDSIARSP 224
              +R+  SR RSRS++   RS S  +S+S S  +++ S ++SRS  R    S S++RSP
Sbjct: 178 EGSKRHSRSRSRSRSRT---RSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234

Query: 225 C--KSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
              KS K  ++S +K   A     RS SRSRS
Sbjct: 235 VPEKSQKRGSSSRSK-SPASVDRQRSRSRSRS 265



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 53/164 (32%), Positives = 76/164 (46%), Gaps = 42/164 (25%)

Query: 56  VQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSP 115
           V+F    D ++A+  L+ K + GR+I++            ++  +RH         SRS 
Sbjct: 149 VEFASYGDLKNAIEKLSGKEINGRKIKL------------IEGSKRH---------SRSR 187

Query: 116 SQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFG 175
           S+ R+R+RSSS  R+R RS S K       SYS+S+SRS+S  R                
Sbjct: 188 SRSRSRTRSSSRSRSRSRSRSRK-------SYSRSRSRSRSRSRSK-------------- 226

Query: 176 SRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDS 219
           SR  SRS   +K  K    S+S SP       ++SRS  R  DS
Sbjct: 227 SRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDS 270


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 76/276 (27%), Positives = 127/276 (46%), Gaps = 43/276 (15%)

Query: 12  LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
           ++I  ++   R  D+ R F  YG I++V +          G+ +V+F+D+RDA+DA+Y L
Sbjct: 4   VYIGRLSYQARERDVERFFKGYGKILEVDLK--------NGYGFVEFDDLRDADDAVYEL 55

Query: 72  NRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTR------SRSS 125
           N K +CG ++ ++ A+G R+       +  +    S   +   P++   R      S   
Sbjct: 56  NGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRC 115

Query: 126 SW----GRNRRRSDSLKESRHRR---------FSYSQSKSRSKSLPRRSTSARQSR---- 168
           SW       R+  +      H+           SYS  K   + L     + R+ R    
Sbjct: 116 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175

Query: 169 ----TPRRNFG-----SRGRSRSK-SLQKRSKS-IGKSQSSSPQKQTSSGTKSRSHGRHS 217
                 RR++      SR RSRS+ S + RS+S   KS  S  + ++ SG++SRS  R S
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR-S 234

Query: 218 DSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSR 253
            S +RS  K  K  + S+ K ++  HS  +S S+S+
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270



 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 76/262 (29%), Positives = 120/262 (45%), Gaps = 20/262 (7%)

Query: 3   RYTRPPNTS--LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60
           +Y  P  T   L + N++     +DL+    + G +       D +  R +    ++F  
Sbjct: 95  KYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYA----DAHKGR-KNEGVIEFVS 149

Query: 61  VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRT 120
             D + AL  L+   V GR+I +         PG  + +           RSRS   R++
Sbjct: 150 YSDMKRALEKLDGTEVNGRKIRLV-----EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKS 204

Query: 121 RSRS----SSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFG- 175
           RSRS    SS  ++R RS S   SR +  S SQS+SRSK    RS S  +SR+   + G 
Sbjct: 205 RSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGK 264

Query: 176 SRGRSRSKSLQK--RSKSIGKSQSSSPQKQTS-SGTKSRSHGRHSDSIARSPCKSPKGYT 232
           SR +S+ ++ +K   + ++GK +S SP +  S S ++SRS  R  +   R      +   
Sbjct: 265 SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE 324

Query: 233 NSETKVQTAKHSHFRSHSRSRS 254
            S  + ++   S   S SRSRS
Sbjct: 325 KSLRQSRSRSRSKGGSRSRSRS 346



 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 22/180 (12%)

Query: 91  KTPGQMKSKERHPCSPSDHR------------RSRSPSQRRTRSRSSSWGRNRRRSDSLK 138
           ++P + KSK +      + R            RS+  S R++RSRS S G +R RS S  
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348

Query: 139 ESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSS 198
           +S+ +R    +S+  S+S   RS S  +S   R+    R      S +K+ +   +SQS 
Sbjct: 349 KSKDKRKGRKRSREESRS---RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405

Query: 199 SPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHS----HFRSHSRSRS 254
           SP +  S   K R H +   S      +S    TN ET+ ++  +S    +  S SRSRS
Sbjct: 406 SPSRSVS---KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462



 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 16/195 (8%)

Query: 79  RQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLK 138
           R  E +  +  R +  + +S+E+         RS+  S+ R+RSRS S  + + R  S +
Sbjct: 303 RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362

Query: 139 ESRHRRFSYSQSK-------------SRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSL 185
           ESR R  S S+S+               SK   +  T   QSR+P R+  S+ R  +KS 
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV-SKEREHAKSE 421

Query: 186 QKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSH 245
             + +  G+S+++   ++T S  +SRS+ +   ++        K  + + ++ ++   S 
Sbjct: 422 SSQREGRGESENAGTNQETRS--RSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479

Query: 246 FRSHSRSRSYRHKNS 260
            RS SRSRS  H  S
Sbjct: 480 SRSPSRSRSRSHSRS 494



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 62/196 (31%), Positives = 87/196 (44%), Gaps = 42/196 (21%)

Query: 97  KSKERHPC-SPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKE---------------- 139
           KS+ R    S S   +SRSPS+ ++RSRS S G++R +S    E                
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290

Query: 140 -SRHRRFSYSQSKSRSKSLPRRSTSARQSRTPR--------RNFGSR----------GRS 180
            SRH+    S+SKSRS+S  RR    ++    R        R   SR           RS
Sbjct: 291 PSRHK----SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346

Query: 181 RSKSLQKR-SKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTN-SETKV 238
           RSKS  KR  +   + +S S  +  S   +SR  G   DS A S  K  K  T+ S+++ 
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS 406

Query: 239 QTAKHSHFRSHSRSRS 254
            +   S  R H++S S
Sbjct: 407 PSRSVSKEREHAKSES 422


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 60/171 (35%), Positives = 82/171 (47%), Gaps = 26/171 (15%)

Query: 98  SKERH------PCSPSDHRRSRSPSQRRT--RSRSSSWGRNRRRSDSLKESRHRRFSYSQ 149
           SKER       P    DHRRSRSPS+ R   +SRSSS  R+ RRS S  + R RR S S 
Sbjct: 480 SKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539

Query: 150 SKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTK 209
           +K R +S  R  +  R+ R  R     R R R +S  K  +          ++Q+ S ++
Sbjct: 540 NKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERE----------RRQSRSSSE 589

Query: 210 SRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
            R H R     +RSP K   GY  S  +  + + +H RS + S+   H  S
Sbjct: 590 ERDHSR-----SRSPNKQ-SGY--SRPRASSKEKAHSRSRTPSKEGNHSQS 632



 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 58/166 (34%), Positives = 81/166 (48%), Gaps = 15/166 (9%)

Query: 98  SKERHPCSPSDHRRSRSPSQRRTR--SRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSK 155
           SKER      DHRRSRSPS+ R R  SRS +  R+R +S S  E R  R S S SK R +
Sbjct: 516 SKER------DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR 569

Query: 156 SLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGR 215
              R  +  R+ R  R +   R  SRS+S  K+S    + ++SS +K  S        G 
Sbjct: 570 RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQS-GYSRPRASSKEKAHSRSRTPSKEGN 628

Query: 216 HSDSIARS----PCKS--PKGYTNSETKVQTAKHSHFRSHSRSRSY 255
           HS S   S    P +S  P+      +  +T+  S  R+ S++ S+
Sbjct: 629 HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674



 Score = 67.8 bits (164), Expect = 9e-12
 Identities = 58/182 (31%), Positives = 86/182 (47%), Gaps = 16/182 (8%)

Query: 86  AQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRS--RSSSWGRNRRRSDSLKESRHR 143
           +Q    + G+ +++ R P     H  SR+PS+ R+ S  RSSS  R+ R S S ++   R
Sbjct: 330 SQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR 389

Query: 144 RFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQK- 202
             S S +K R  S  R    AR     R  + +R RSRS+S  K       S+S SP K 
Sbjct: 390 SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDC---SRSRSPYKA 446

Query: 203 ----QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHK 258
               ++ S  K+R H R     +RSP K+ +  + S +  +   HS   S S+ R +R  
Sbjct: 447 RDRSRSRSPNKARDHSR-----SRSPNKA-RDRSRSRSPSKERDHSQLGSPSKERDHRRS 500

Query: 259 NS 260
            S
Sbjct: 501 RS 502



 Score = 67.8 bits (164), Expect = 9e-12
 Identities = 59/161 (36%), Positives = 77/161 (47%), Gaps = 14/161 (8%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRS---DSLKESRHRRFSYSQSKSR 153
           +S+ R P    DH RSRSP++ R RSRS S  + R  S      KE  HRR S S SK R
Sbjct: 449 RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRR-SRSPSKER 507

Query: 154 SKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSH 213
                R S+  R  R  R     R R +S+S    +K   +SQS SP ++     +SRS 
Sbjct: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRS---PNKERDRSQSRSPSEEREH-RQSRSP 563

Query: 214 GRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
            +  D   R   +SP   +    + Q+   S  R HSRSRS
Sbjct: 564 SKERD---RRRWRSP---SKERERRQSRSSSEERDHSRSRS 598



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 59/181 (32%), Positives = 78/181 (43%), Gaps = 18/181 (9%)

Query: 90  RKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSS--WGRNRRRSDSLKESRHRRFSY 147
           RK  G  +S+   P    DH RSRSP++ R RSRS S    R+R RS S  ++R    S 
Sbjct: 384 RKESG--RSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441

Query: 148 SQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKR---------SKSIGKSQSS 198
           S  K+R +S  R    AR     R    +R RSRS+S  K          SK     +S 
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501

Query: 199 SPQK-----QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSR 253
           SP K     Q+ S +K R H R          +  +       + Q+   S  R H +SR
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561

Query: 254 S 254
           S
Sbjct: 562 S 562



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 52/144 (36%), Positives = 73/144 (50%), Gaps = 16/144 (11%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRS--RSSSWGRNRRRSDSLKESRHRRFSYSQSKSRS 154
           +S+ R P    +HR+SRSPS+ R R   RS S  R RR+S S  E R    S S +K   
Sbjct: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604

Query: 155 KSLPRRSTSAR---QSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQ----KQTSSG 207
            S PR S+  +   +SRTP +  G+  +SR+      SK    SQS+ P+    K++ + 
Sbjct: 605 YSRPRASSKEKAHSRSRTPSKE-GNHSQSRTS-----SKESDPSQSTVPRSPDWKRSPTR 658

Query: 208 TKSRSHGR-HSDSIARSPCKSPKG 230
           T S S  R  S + + SP   P G
Sbjct: 659 TSSLSQNRTPSKTSSHSPSTFPSG 682



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 65/174 (37%), Positives = 81/174 (46%), Gaps = 40/174 (22%)

Query: 85  FAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSR--SSSWGRN--RRRSDSLKES 140
           + Q   ++  Q  S+ R P      RRSRS SQ+RT SR  S SW RN  R RS + K  
Sbjct: 269 YNQASTRSRPQSHSQSRSP------RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI 322

Query: 141 RHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSP 200
             +   +SQS+S SK       S  QSRTPRR     GRS + S   R+ S  +S S S 
Sbjct: 323 LSQMGRHSQSRSHSKG-----KSQNQSRTPRR-----GRSHNWS---RNPSKERSHSHS- 368

Query: 201 QKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
                S +K R H R S S  +   +S  G  N +           R HSRSRS
Sbjct: 369 ----RSSSKERDH-RGSSSPRKESGRSQSGSPNKQ-----------RDHSRSRS 406



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 47/152 (30%), Positives = 70/152 (46%), Gaps = 9/152 (5%)

Query: 95  QMKSKERHPCSPSDHRRSRSPSQRR--TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKS 152
           + + + R P    D  +SRSPS+ R   +SRS S  R+RRR  S  + R RR S S S+ 
Sbjct: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590

Query: 153 RSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRS 212
           R  S  R          PR +   +  SRS++  K      +S++SS +   S  T  R 
Sbjct: 591 RDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNH-SQSRTSSKESDPSQSTVPR- 648

Query: 213 HGRHSDSIARSPCKSPKGYTNSETKVQTAKHS 244
               S    RSP ++    + + T  +T+ HS
Sbjct: 649 ----SPDWKRSPTRT-SSLSQNRTPSKTSSHS 675



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 62/192 (32%), Positives = 91/192 (47%), Gaps = 23/192 (11%)

Query: 78  GRQIEIQFAQGDRK--TPGQMKSKERHPC-SPSDHRRSRSPSQRRTRSRSSSWG----RN 130
           GR  E+       K  TP  + SKE+    SPS  R+ +S  Q    SR  S+      +
Sbjct: 205 GRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSS 264

Query: 131 RRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSK 190
           R +S +   +R R  S+SQS+S     PRRS S  Q RT      SR RS S    KR+ 
Sbjct: 265 RVKSYNQASTRSRPQSHSQSRS-----PRRSRSGSQKRTH-----SRVRSHS---WKRNH 311

Query: 191 SIGKSQSSSP-QKQTSSGTKSRSHGR-HSDSIARSPCKSPKGYTNSETKVQTAKHSHFRS 248
           S  +S++      Q    ++SRSH +  S + +R+P +  + +  S    +   HSH RS
Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRG-RSHNWSRNPSKERSHSHSRS 370

Query: 249 HSRSRSYRHKNS 260
            S+ R +R  +S
Sbjct: 371 SSKERDHRGSSS 382



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 54/175 (30%), Positives = 84/175 (48%), Gaps = 17/175 (9%)

Query: 90  RKTPGQMKSKERHPCSPSDHRRSRSPSQRRT--RSRSSSWGRNRRRSDSLKESRHRRFSY 147
           R   G +    RH  S S H + +S +Q RT  R RS +W RN         S+ R  S+
Sbjct: 317 RTRKGILSQMGRHSQSRS-HSKGKSQNQSRTPRRGRSHNWSRN--------PSKER--SH 365

Query: 148 SQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKR-SKSIGKSQSSSPQKQTSS 206
           S S+S SK    R +S+ +  + R   GS  + R  S  +  +K+  +S+S SP K    
Sbjct: 366 SHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYK-ARD 424

Query: 207 GTKSRSHGRHSD-SIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
            ++SRS  +  D S +RSP K+ +  + S +  +   HS  RS +++R      S
Sbjct: 425 RSRSRSPNKARDCSRSRSPYKA-RDRSRSRSPNKARDHSRSRSPNKARDRSRSRS 478



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 48/211 (22%)

Query: 91  KTPGQM--KSKERHPCSPSDHRRSRSPSQRRTRSR--SSSWGRNRRRSDSLKE----SRH 142
           K+ GQM   S+E+         R +S +Q  TRSR  S S  R+ RRS S  +    SR 
Sbjct: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRV 302

Query: 143 RRFSYSQSKSRSKSLPR-----------------RSTSARQSRTPRRNFG---------- 175
           R  S+ ++ SR++S  R                 +  S  QSRTPRR             
Sbjct: 303 RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKE 362

Query: 176 ---SRGRSRSKSLQKRS-----KSIGKSQSSSPQKQTSSGTKSRSHGRHSD-SIARSPCK 226
              S  RS SK    R      K  G+SQS SP KQ    ++SRS  +  D S +RSP K
Sbjct: 363 RSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDH-SRSRSPNKARDRSRSRSPYK 421

Query: 227 S-PKGYTNSETKVQTAKHSH--FRSHSRSRS 254
           +  +  + S  K +    S   +++  RSRS
Sbjct: 422 ARDRSRSRSPNKARDCSRSRSPYKARDRSRS 452



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 33/190 (17%)

Query: 92  TPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGR----NRRRSDSLKES------- 140
           TPG++++   H   P    R R+P+ ++  SR  S+GR    NR RSDS   +       
Sbjct: 141 TPGRIRT---HGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYR 197

Query: 141 --------RHRRFSYSQSKSRSKS---LPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRS 189
                   R    + + S ++ ++   +P +  S   S +  R   S G+     +  R 
Sbjct: 198 PPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQ---MIIPSRE 254

Query: 190 KSIGKSQSSSPQKQ-TSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRS 248
           KS   ++ SS  K    + T+SR     S S +RSP +S  G +   T  +   HS  R+
Sbjct: 255 KSYSPTEMSSRVKSYNQASTRSRP---QSHSQSRSPRRSRSG-SQKRTHSRVRSHSWKRN 310

Query: 249 HSRSRSYRHK 258
           HSR+RS   K
Sbjct: 311 HSRARSRTRK 320



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 42/183 (22%), Positives = 72/183 (39%), Gaps = 29/183 (15%)

Query: 107 SDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRR-----------FSYSQSKSRSK 155
           S  +RS  PS     S SS    + +   SLK ++               S +   S S 
Sbjct: 2   SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61

Query: 156 SLPRRSTSARQSRTPRRNFGSRGRSRSK-----SLQKRSKSIGKSQSSSPQKQTSSGTKS 210
           S   +STS +++ + R +  SR RS+++     S   R+    K+      ++  + ++ 
Sbjct: 62  SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121

Query: 211 RSHGRH-SDSIARSPCKS------------PKGYTNSETKVQTAKHSHFRSHSRSRSYRH 257
           R+ GR  S S  RSP ++            P   +   T     K S  +S+ R R+   
Sbjct: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181

Query: 258 KNS 260
           + S
Sbjct: 182 ERS 184


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 71.2 bits (173), Expect = 8e-13
 Identities = 60/177 (33%), Positives = 95/177 (53%), Gaps = 25/177 (14%)

Query: 91  KTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHR-RFSYSQ 149
           +TP + +S+ R P       RSR+P++RR+R+RS    R+R RS + +  R R R    +
Sbjct: 597 RTPTRRRSRSRTPARRG-RSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR 655

Query: 150 SKSRSKSLPRRSTSARQSRTPRRNFG--------SRGRSRSKSLQK---RSKSI---GKS 195
            +SRS++  RR  S  +SRTP R  G         RGRSRS++ ++   RS+S+   G+S
Sbjct: 656 GRSRSRTPARRGRS--RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713

Query: 196 QSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRS 252
            S +PQ++  SG+ S    +   S  RS        +NS  +++ ++ S  RS S S
Sbjct: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRS-------RSNSSPEMKKSRISSRRSRSLS 763



 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 62/171 (36%), Positives = 100/171 (58%), Gaps = 24/171 (14%)

Query: 91  KTPGQM-KSKERHPCSPSDHRRSRSPSQRRTRSRSSSW-GRNRRRSDSLKESRHRRFSYS 148
           +TP +  +S+ R P       RSR+P++RR+RSR+ +  GR+R R+ + + SR R  S  
Sbjct: 576 RTPARRGRSRSRTPARRRS--RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR--SPV 631

Query: 149 QSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGT 208
           + +SRS+S  RRS  +R SRTP R    RGRSRS++  +R    G+S+S +P ++ S  +
Sbjct: 632 RRRSRSRSPARRSGRSR-SRTPAR----RGRSRSRTPARR----GRSRSRTPARR-SGRS 681

Query: 209 KSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKN 259
           +SR+  R   S +R+P    +G + S + V+       RSHSR+   R ++
Sbjct: 682 RSRTPARRGRSRSRTP---RRGRSRSRSLVRRG-----RSHSRTPQRRGRS 724



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 55/172 (31%), Positives = 86/172 (50%), Gaps = 19/172 (11%)

Query: 88  GDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSS-WGRNR---RRSDSLKESRHR 143
           G  ++P   K       +P+    SRS S +  RSRS+  WGR+R   RR  S    R  
Sbjct: 482 GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP- 540

Query: 144 RFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQ 203
                 S+SR+     RS SAR+ R+  R+  +RGRSRS++  +R    G+S+S +P ++
Sbjct: 541 ----GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARR----GRSRSRTPARR 592

Query: 204 TS-SGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
            S S T +R   R     +R+P +  +  + +  + ++   S  R  SRSRS
Sbjct: 593 RSRSRTPTRRRSR-----SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRS 639



 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 62/193 (32%), Positives = 97/193 (50%), Gaps = 36/193 (18%)

Query: 97  KSKERHPCSPSDHRRSRSPS------------QRRTRSRSSSWGRNRRRSDSLKESRHRR 144
           +S +R   S S  RR RS S            QRR RSRS+  GR+  RS + +     R
Sbjct: 517 RSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSR 576

Query: 145 FSYSQSKSRSKSLPRRSTSAR-------QSRTPRRNFGSRGRSRSKS-LQKRSKSIG--- 193
               + +SRS++  RR + +R       +SRTP R    RGRSRS++  ++RS++     
Sbjct: 577 TPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR----RGRSRSRTPARRRSRTRSPVR 632

Query: 194 -KSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRS---- 248
            +S+S SP ++ S  ++SR+  R   S +R+P +  +G + S T  + +  S  R+    
Sbjct: 633 RRSRSRSPARR-SGRSRSRTPARRGRSRSRTPAR--RGRSRSRTPARRSGRSRSRTPARR 689

Query: 249 -HSRSRSYRHKNS 260
             SRSR+ R   S
Sbjct: 690 GRSRSRTPRRGRS 702



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 52/179 (29%), Positives = 84/179 (46%), Gaps = 18/179 (10%)

Query: 91  KTPGQM-KSKERHPCSPSDHRRSRSPSQR-RTRSRSSSWGRNRRRS--------DSLKES 140
           +TP +  +S+ R P   S   RSR+P++R R+RSR+   GR+R RS            + 
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720

Query: 141 RHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRG-------RSRSKSLQKRSKSIG 193
           R R  S S+ K++S++  RRS S       +    SR        RS++KS     +S+ 
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS 780

Query: 194 KSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRS 252
            S     QK  +   +SRS      + +R+P +  +  ++   K Q +K    +SHS S
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK-QKSKTPSRQSHSSS 838



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 25/197 (12%)

Query: 73  RKWVCGRQIEIQFAQGDRKTPGQMKSK--ERHPCSPSDHR---RSRSPSQR-RTRSRSSS 126
           ++W   R  + +      + PG  +S+  +R   S S  R    SRSP+ R R+RSR+ +
Sbjct: 520 QRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA 579

Query: 127 W-GRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGS-----RGRS 180
             GR+R R+ + + SR R  + ++ +SRS++  RR  S  +SRTP R         R RS
Sbjct: 580 RRGRSRSRTPARRRSRSR--TPTRRRSRSRTPARRGRS--RSRTPARRRSRTRSPVRRRS 635

Query: 181 RSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT 240
           RS+S  +RS   G+S+S +P ++  S  +SR+  R   S +R+P +   G + S T  + 
Sbjct: 636 RSRSPARRS---GRSRSRTPARRGRS--RSRTPARRGRSRSRTPARR-SGRSRSRTPARR 689

Query: 241 AK---HSHFRSHSRSRS 254
            +    +  R  SRSRS
Sbjct: 690 GRSRSRTPRRGRSRSRS 706



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 57/178 (32%), Positives = 84/178 (47%), Gaps = 25/178 (14%)

Query: 90   RKTPGQMKSKERHPCSPSDHRRSRS--PSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSY 147
            R +P   K + R   SP+ HRRSRS  P   R RSRS +   +RRRS S      RR   
Sbjct: 1855 RTSPAPWK-RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR--- 1910

Query: 148  SQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKS------IGKSQSSSP- 200
              S+SR+  + RR + +R     RR    R RSR+ + ++RS+S        +S+S +P 
Sbjct: 1911 --SRSRASPVSRRRSRSRTPPVTRR----RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPP 1964

Query: 201  ------QKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRS 252
                  + +TS  T+ RS  R S    R         T   ++ +T+  +  RS SR+
Sbjct: 1965 VTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2022



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 27/198 (13%)

Query: 87   QGDRKTPGQMKSKERHP-------CSPSDHRRSRSPSQRRTRSRSSS-WGRNR-----RR 133
            +G R +P + K+K R P        SP   R++R    RR+RS SSS   R+R     RR
Sbjct: 1670 RGSRSSP-EPKTKSRTPPRRRSSRSSPELTRKARL--SRRSRSASSSPETRSRTPPRHRR 1726

Query: 134  SDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSI- 192
            S S+        S S  + RS S PR  T++R+ R+P        RSRS+S ++++++  
Sbjct: 1727 SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786

Query: 193  -----GKSQSSSPQKQTSSGTKSRSHGRHSDS--IARSPCKSPKGYTNSET---KVQTAK 242
                 G SQS+S ++Q S      +  R   S   +RSP +     T+S     + +T  
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846

Query: 243  HSHFRSHSRSRSYRHKNS 260
             S  RS SR+     K S
Sbjct: 1847 TSRKRSRSRTSPAPWKRS 1864



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 54/176 (30%), Positives = 87/176 (49%), Gaps = 17/176 (9%)

Query: 90  RKTPGQMKSKER-HPCSPSDHRRSRSPSQRRTRSRSSSW---GRNRRRSDSLK-ESRHRR 144
           R+      SK R H  +  D   S +PS+R  RSRS +    GR+R R+ + +  SR R 
Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS 510

Query: 145 FSYSQSKSRSKSLPRRSTSAR-QSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQ 203
             + +S+S  +    RS   R +SR+P+R   SR R+  +  + RS   G+S S SP   
Sbjct: 511 PQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPA-- 568

Query: 204 TSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKN 259
           T   ++SR+  R   S +R+P +       S ++  T +    RS SR+ + R ++
Sbjct: 569 TRGRSRSRTPARRGRSRSRTPARR-----RSRSRTPTRR----RSRSRTPARRGRS 615



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 58/193 (30%), Positives = 79/193 (40%), Gaps = 21/193 (10%)

Query: 86   AQGDRKTPGQMKSKERHPCSPSDHRRS----------RSPSQRRTRSRSSSWGRNRRRSD 135
            A+  R++     S E    +P  HRRS          +S S RR RS SS   +   R  
Sbjct: 1701 ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRG 1760

Query: 136  SLKESRHRRFSYSQSKSR---SKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSI 192
                 + R    S+S+SR   +++  RR  S     T RR   SR RSR   + +R +  
Sbjct: 1761 RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR---VTRRRRGG 1817

Query: 193  GKSQSSSPQKQTSSGTKSRSHGRHS----DSIARSPCK-SPKGYTNSETKVQTAKHSHFR 247
                S SP +Q SS T SR     S     S  RS  + SP  +  S ++   A H   R
Sbjct: 1818 SGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877

Query: 248  SHSRSRSYRHKNS 260
            S +   S R   S
Sbjct: 1878 SRTPLISRRRSRS 1890



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 53/174 (30%), Positives = 76/174 (43%), Gaps = 7/174 (4%)

Query: 91  KTPGQM-KSKERHPCSPSDHRRSRSPSQRRTRSRS---SSWGRNRRRSDSLKESRHRRFS 146
           +TP +  +S+ R P       RSR+P++R  RSRS   +  GR+R R+     SR R   
Sbjct: 650 RTPARRGRSRSRTPARRG-RSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL- 707

Query: 147 YSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSS 206
             + +S S++  RR  S   S    ++  S+ RSRS S  +  KS   S+ S       S
Sbjct: 708 VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRS 767

Query: 207 GTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
             KSR   R S S   SPC   K  T        +     +S +  R  R  +S
Sbjct: 768 KAKSRLSLRRSLS-GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 49/151 (32%), Positives = 71/151 (47%), Gaps = 30/151 (19%)

Query: 91  KTPGQMKSKER--------HPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKES-- 140
           +TP + +S+ R        H  +P    RS S S+R+ +SR+S        S  +K+S  
Sbjct: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754

Query: 141 ---RHRRFSYSQSKSRSKSLPRRSTSA------RQSRTPRRNFGSRGRSRSKSLQKRSKS 191
              R R  S  +SK++S+   RRS S       ++S+TP R      RSRS S Q ++KS
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR------RSRSGSSQPKAKS 808

Query: 192 -----IGKSQSSSPQKQTSSGTKSRSHGRHS 217
                  +S SS P KQ S     +SH   S
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSS 839



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 51/167 (30%), Positives = 80/167 (47%), Gaps = 13/167 (7%)

Query: 102  HPCSPSDHRRSRSPSQRR-TRSRSSSWGRNRRRSDS----LKESRHRR--FSYSQSKSRS 154
            H  SP+    SR+ S+RR  RSR+    R R RS +     K SR R    ++ +S+SR+
Sbjct: 1821 HSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT 1880

Query: 155  KSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQS-SSPQKQTSSGTKSRSH 213
              + RR + +R S   RR    R RSR+   ++RS+S     S    + +T   T+ RS 
Sbjct: 1881 PLISRRRSRSRTSPVSRR----RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR 1936

Query: 214  GRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
             R   +  RS  ++P   T   ++ +T   +  RS SR+     + S
Sbjct: 1937 SRTPTTRRRSRSRTPP-VTRRRSRSRTPPVTRRRSRSRTSPITRRRS 1982



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 53/170 (31%), Positives = 85/170 (50%), Gaps = 22/170 (12%)

Query: 97   KSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKS 156
            +S+ R P       RSR+P   R RSRS +    RRRS S      RR    +S+SR+  
Sbjct: 1945 RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRR----RSRSRTSP 2000

Query: 157  LPRRSTSARQSRTPRRNFGSRGRSRS-KSLQKRSKS------IGKSQSSSP---QKQTSS 206
            + RR + +R S   RR    R RSR+  ++++RS+S        +S+S SP   ++++ S
Sbjct: 2001 VTRRRSRSRTSPVTRR----RSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRS 2056

Query: 207  GTKSRSHGRHSDSIARSP--CKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
             T   + G+   S+ RSP   +      +S  + ++A     R+HS SR+
Sbjct: 2057 RTPRTARGKR--SLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRT 2104



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 49/184 (26%), Positives = 79/184 (42%), Gaps = 24/184 (13%)

Query: 92  TPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRF-SYSQS 150
           +P   K       SP   + + +P   R  S SS   +NR    + ++  H    S    
Sbjct: 424 SPQPTKVSRHASSSPESPKPAPAPGSHREIS-SSPTSKNRSHGRAKRDKSHSHTPSRRMG 482

Query: 151 KSRSKSLPRRSTSARQSRTPRRNFGSRGRS----RSKSLQKRSKSIG---KSQSSSPQK- 202
           +SRS +  +R  S  +SRTP +   SR RS    RS+S Q+  +S     + +S SPQ+ 
Sbjct: 483 RSRSPATAKRGRS--RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540

Query: 203 ------------QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHS 250
                       ++ S  + RSH R   +  RS  ++P     S ++    + S  R+ +
Sbjct: 541 GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600

Query: 251 RSRS 254
           R RS
Sbjct: 601 RRRS 604



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 49/178 (27%), Positives = 80/178 (44%), Gaps = 14/178 (7%)

Query: 87   QGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFS 146
            +G  +TP   + + R   SP+  +RSRS +   T  RS    R+R    S + SR R   
Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS----RSRTPLISRRRSRSRTSP 1894

Query: 147  YSQSKSRSKSLPRRSTSARQSRT-PRRNFGSRGRSRSKS---LQKRSKSIGKSQSSSPQK 202
             S+ +SRS+      TS  + R+  R +  SR RSRS++    ++RS+S   +     + 
Sbjct: 1895 VSRRRSRSR------TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS 1948

Query: 203  QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
            +T   T+ RS  R      R         T   ++ +T+  +  RS SR+     + S
Sbjct: 1949 RTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 12/165 (7%)

Query: 67  ALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSS 126
           A + ++  +V G   + Q    + K P     K       S   RS +P Q++ + +   
Sbjct: 137 AAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKD- 195

Query: 127 WGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQ 186
                RRS+S    R R+ S  + K RS+S  ++      +   +R    + R RS+S  
Sbjct: 196 ---RGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT 252

Query: 187 KRSKSIGKSQSSSPQKQTSSGTKSRSHGR------HSDSIA-RSP 224
              KS    +S+S    +SS T SRS  R      H+ ++A RSP
Sbjct: 253 PAPKSRRAHRSTSADSASSSDT-SRSRSRSAAAKTHTTALAGRSP 296



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 52/175 (29%), Positives = 76/175 (43%), Gaps = 17/175 (9%)

Query: 89  DRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYS 148
           DR  P   KS E+ P S S      SP   +    +SS   + + + +     HR  S S
Sbjct: 402 DRSPP---KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA--PGSHREISSS 456

Query: 149 Q-SKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSG 207
             SK+RS    +R  S   S TP R  G   RSRS +  KR    G+S+S +P K+  S 
Sbjct: 457 PTSKNRSHGRAKRDKS--HSHTPSRRMG---RSRSPATAKR----GRSRSRTPTKRGHSR 507

Query: 208 TKSRS--HGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
           ++S      R +    RS     +G + S  +   ++  + +   RSRS R   S
Sbjct: 508 SRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS 562



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 11/149 (7%)

Query: 89   DRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYS 148
            D K     + +     SP    ++R+P ++R+RS SS    ++ R   L   R R  S  
Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR---LSPRRSRSGSSP 1602

Query: 149  QSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGT 208
            + K + ++ PR  + +  S  P+           ++L +RS+S   S+   P  + SS T
Sbjct: 1603 EVKDKPRAAPRAQSGSDSSPEPK-------APAPRALPRRSRSGSSSKGRGPSPEGSSST 1655

Query: 209  KSR-SHGRHSDSIARSPCKSPKGYTNSET 236
            +S   H   S +  R    SP+  T S T
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 48/172 (27%), Positives = 69/172 (40%), Gaps = 19/172 (11%)

Query: 80   QIEIQFAQGDRKTPGQMKS-KERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLK 138
            Q E+   +    TP   ++ +E  P  P+  +R R  S   + S SSS   +   S S  
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630

Query: 139  ESRHRRFSYSQSKSRSKS----------LPRRST------SARQSRTPRRNFGSRGRSRS 182
             S     S S S S S S          LP+ ++        R+SR+PR+   S   SRS
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS 2690

Query: 183  KSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNS 234
             S     +     Q S   +Q+SS  +    G+  DS  RSP    +  T S
Sbjct: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDS--RSPSHKRRRETPS 2740



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 45/162 (27%), Positives = 69/162 (42%), Gaps = 17/162 (10%)

Query: 78  GRQIEIQFAQGDRKTPGQMK-------SKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRN 130
           GR+ E    + +RK   + K       SK+R   SP+   + +S  ++R RSRS++    
Sbjct: 197 GRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPK 256

Query: 131 RRRSDSLKESRHRRFSYSQSKSRSKSLPRRS-TSARQSRTPRRNFGSRGR--------SR 181
            RR+     S     S   S+SRS+S   ++ T+A   R+P    G RG           
Sbjct: 257 SRRAHR-STSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGT 315

Query: 182 SKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARS 223
           + + +  S      Q SSP +      K +S  R S S  RS
Sbjct: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERS 357



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 4/161 (2%)

Query: 98   SKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSL 157
            S E  P S +  R SRS  + +T+SR+    R+ R S  L  +R  R S     + S   
Sbjct: 1658 SPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL--TRKARLSRRSRSASSSPE 1715

Query: 158  PRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHS 217
             R  T  R  R+P  +          S ++RS S  +++++S ++  S   K R   R  
Sbjct: 1716 TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS-RRGRSPSPKPRGLQRSR 1774

Query: 218  DSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHK 258
                R   ++ +    S +   T++    RS SRSR  R +
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQ-RSRSRSRVTRRR 1814



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 60/177 (33%), Positives = 83/177 (46%), Gaps = 33/177 (18%)

Query: 97   KSKERHPCSPSDH----RRSRSPSQR--------RTRSRSS-SWGRNRRRSDSLKESRHR 143
            K+  R   SPS      +RSRS S+R        R RS SS S  R R+RS S      R
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813

Query: 144  RFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRS-KSLQKRSKSIGKSQSSSPQK 202
            R   S   SRS   P R  S+R S   R     RGRSR+  + +KRS+S     S +P K
Sbjct: 1814 RRGGSGYHSRS---PARQESSRTSSRRR-----RGRSRTPPTSRKRSRS---RTSPAPWK 1862

Query: 203  QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKN 259
            ++ S     +H R   S +R+P  S +      ++ +T+  S  RS SR+   R ++
Sbjct: 1863 RSRSRASPATHRR---SRSRTPLISRR-----RSRSRTSPVSRRRSRSRTSVTRRRS 1911



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 38/131 (29%), Positives = 48/131 (36%), Gaps = 16/131 (12%)

Query: 115  PSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRR-------------- 160
            P++ R  S SSS   +   S S   S       S S S   SLP +              
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585

Query: 161  -STSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDS 219
               + R+ R P      R R RS S    S S   S SSS    +SS + S S    S S
Sbjct: 2586 PKEAVREGRPPEPTPAKRKR-RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 220  IARSPCKSPKG 230
             + SP  +  G
Sbjct: 2645 SSSSPSPAKPG 2655



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 21/155 (13%)

Query: 118  RRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSR 177
            RR+RS SSS GR      S         S  +   +S++  R S S+ + +T  R    R
Sbjct: 1634 RRSRSGSSSKGRGPSPEGSSSTE-----SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688

Query: 178  GRSRSK-SLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIA-------------RS 223
              SRS   L ++++   +S+S+S   +T S T  R   R S S++             R 
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH--RRSPSVSSPEPAEKSRSSRRRR 1746

Query: 224  PCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHK 258
               SP+  T S      +        SRSRS R K
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 49/174 (28%), Positives = 68/174 (39%), Gaps = 19/174 (10%)

Query: 2    SRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDV 61
            SR   PP T    R     T P   RR   R  PI          TRR R  +       
Sbjct: 1946 SRSRTPPVTR---RRSRSRTPPVTRRRSRSRTSPI----------TRR-RSRSRTSPVTR 1991

Query: 62   RDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQM--KSKERHPCSPSDHRRSRSP--SQ 117
            R +      + R+    R   +   +   +TP  +  +S+ R P  P    RSRSP   +
Sbjct: 1992 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIR 2051

Query: 118  RRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKS-LPRRSTSARQSRTP 170
            RR+RSR+    R +R       +  RR +   S  RS+S  P  + +   SRTP
Sbjct: 2052 RRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTP 2105



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 17/171 (9%)

Query: 88  GDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSY 147
           G  +TPGQ       P     H+ +    ++  R R++ +G +    D       RR   
Sbjct: 107 GKEETPGQ------RPAVTETHQLAELNEKKNERLRAA-FGISDSYVDGSSFDPQRRAR- 158

Query: 148 SQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIG-KSQSSSPQKQTSS 206
            ++K  +   P+  +  R+S +      SR  +  +  +K+ K  G +S+SSSP+++   
Sbjct: 159 -EAKQPAPEPPKPYSLVRESSS------SRSPTPKQKKKKKKKDRGRRSESSSPRRERKK 211

Query: 207 GTKSRSHGRHSDSIARS-PCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYR 256
            +K + H   S+S  R     +PK    S+ K +    S   +    R++R
Sbjct: 212 SSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHR 262



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 41/141 (29%), Positives = 65/141 (46%), Gaps = 12/141 (8%)

Query: 97   KSKERHPCSPSDHRRSRSPS-QRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSK 155
            ++  RH CS S   R +S +  R++ SRSSS    + +  ++   R R  S S S S S+
Sbjct: 884  RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS---PQPKVKAIISPRQRSHSGSSSPSPSR 940

Query: 156  SLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGT------- 208
               R +    +S +P  N  SR   R  S    S    K +  +P +Q+ SG+       
Sbjct: 941  VTSRTTPRRSRSVSPCSNVESRLLPR-YSHSGSSSPDTKVKPETPPRQSHSGSISPYPKV 999

Query: 209  KSRSHGRHSDSIARSPCKSPK 229
            K+++    S S ++SPC   K
Sbjct: 1000 KAQTPPGPSLSGSKSPCPQEK 1020



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 45/153 (29%), Positives = 64/153 (41%), Gaps = 18/153 (11%)

Query: 105 SPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSA 164
           SP  + +S +P QRR+   SS     + R+ S    RH     S  + +S + PR+S S 
Sbjct: 857 SPQANEQSVTP-QRRSCFESSPDPELKSRTPS----RHSCSGSSPPRVKSSTPPRQSPSR 911

Query: 165 RQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARS- 223
             S  P+             +  R +S   S S SP + TS  T  RS      S   S 
Sbjct: 912 SSSPQPK---------VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962

Query: 224 --PCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
             P  S  G ++ +TKV+       +SHS S S
Sbjct: 963 LLPRYSHSGSSSPDTKVKPETPPR-QSHSGSIS 994



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 48/173 (27%), Positives = 67/173 (38%), Gaps = 24/173 (13%)

Query: 98   SKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSL 157
            S+ER   + S   +   P     RSRS S      R  S   SRH   S S S    K +
Sbjct: 1415 SRERSSSASSPEMKDGLPRTPSRRSRSGS--SPGLRDGSGTPSRH---SLSGSSPGMKDI 1469

Query: 158  PRRSTSAR-------------QSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQK-- 202
            PR  +  R             Q+  PR    S     +K L  + +  G S+SS  QK  
Sbjct: 1470 PRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSG-SESSVDQKTV 1528

Query: 203  -QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
             +T  G +SRS    S  +   P  SP+  + S++   +   +      RSRS
Sbjct: 1529 ARTPLGQRSRSGS--SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 39/154 (25%), Positives = 51/154 (33%), Gaps = 18/154 (11%)

Query: 98   SKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSL 157
            +KER   S S    S S S   + S SSS G +   S+          +  +  S +   
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT--- 2583

Query: 158  PRRSTSARQSRTPRRNFGSRGR---------------SRSKSLQKRSKSIGKSQSSSPQK 202
            P    + R+ R P      R R               S S S    S S   S SSS   
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643

Query: 203  QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSET 236
             +SS       G  +     SP K P G   S +
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS 2677



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 8/80 (10%)

Query: 189  SKSIGKSQSSSPQKQTSS-----GTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTA-- 241
            S  + +S S SP  Q+ S     G +SRS    ++  +RSP +  +G  ++   +++   
Sbjct: 1073 SPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMS 1132

Query: 242  -KHSHFRSHSRSRSYRHKNS 260
             + S F+S S S      NS
Sbjct: 1133 PEQSRFQSDSSSYPTVDSNS 1152


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 70/273 (25%), Positives = 108/273 (39%), Gaps = 38/273 (13%)

Query: 11  SLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYN 70
           +LF+  V   T    LRREF  YGPI  +++     + +PRG+A++++E  RD   A  +
Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163

Query: 71  LNRKWVCGRQIEIQFAQG-------DRKTPG------------QMKSKERHPCSPSDHRR 111
            + K + GR++ +   +G        R+  G             ++   R   S  D R 
Sbjct: 164 ADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERP 223

Query: 112 SRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYS-----QSKSRSKSLPRRSTS-AR 165
             SP   R R R     R R RS    + R RR S S     +S+SR K   RRS   ++
Sbjct: 224 GPSPLPHRDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSK 282

Query: 166 QSRTPRRNFGSRGRSRSKSLQKRSKSI--GKSQSSSPQKQTSSGTKSRSHGRHSDSIARS 223
                R+   SR R R++  ++R + +  G    + P +   +       G         
Sbjct: 283 DKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGE-------- 334

Query: 224 PCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYR 256
               P G    E K +       RSH   R  R
Sbjct: 335 --LGPDGPDGPEEKGRDRDRERRRSHRSERERR 365


>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
          Length = 288

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 61/181 (33%), Positives = 83/181 (45%), Gaps = 13/181 (7%)

Query: 2   SRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDV 61
           +R    PN  L +  ++  T   DLR  F +YGPI DV I  D  +RR RGFA+V FE+V
Sbjct: 110 NRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENV 169

Query: 62  RDAEDALYNLNRKWVCGRQIEIQFAQGDR---KTPGQMKSKERHPCSPS----DHRRSRS 114
            DA++A    N   + GR+I + F+   R    TPG    +  +  S      D    R 
Sbjct: 170 DDAKEAKERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTYGSSRRRDYYDRGYDRG 229

Query: 115 PSQRRTRSRS---SSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPR 171
              R   SRS      G    R+   ++  +RR S S   SR      RS S  +S +PR
Sbjct: 230 YDDRDYYSRSYRGGGGGGGGWRAAQDRDQIYRRRSPSPYYSRG---GYRSRSRSRSYSPR 286

Query: 172 R 172
           R
Sbjct: 287 R 287



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 33/97 (34%), Positives = 52/97 (53%), Gaps = 4/97 (4%)

Query: 167 SRTPRRNFG---SRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARS 223
           S +  +N+G   SR  SRS S     KS   + + S  K+ S  ++S+S  R S+S +RS
Sbjct: 2   SDSGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSR-SESRSRS 60

Query: 224 PCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
              S + YT S ++ ++ + S  RS+SR    RH +S
Sbjct: 61  RRSSRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHS 97



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 37/89 (41%), Positives = 48/89 (53%), Gaps = 9/89 (10%)

Query: 90  RKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQ 149
           R TP + +SKE       D RRSRS S+ R+ SRS S  R+ RR  +   SR R    S+
Sbjct: 31  RHTPARSRSKE-------DSRRSRSKSRSRSESRSRS-RRSSRRHYTRSRSRSRSHRRSR 82

Query: 150 SKSRSKSLPRR-STSARQSRTPRRNFGSR 177
           S+S S+   RR S S     T RR+ G+R
Sbjct: 83  SRSYSRDYRRRHSHSHSPMSTRRRHVGNR 111



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 6/104 (5%)

Query: 122 SRSSSWGRNRRRSDSLKESRH---RRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRG 178
           S   ++G    RS S   S H   +   ++ ++SRSK   RRS S  +SR+  R   SR 
Sbjct: 4   SGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESR---SRS 60

Query: 179 RSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIAR 222
           R  S+    RS+S  +S   S  +  S   + R    HS    R
Sbjct: 61  RRSSRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMSTR 104



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 6/107 (5%)

Query: 112 SRSPSQRRTRSRSSSWGRNRRRSDSLKESRHR----RFSYSQSKSRSKSLPRRSTSARQS 167
           S S  Q      S S  R+     S K +RH     R      +SRSKS  R  + +R  
Sbjct: 2   SDSGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSR 61

Query: 168 RTPRRNFGSRGRSRSKSLQK-RSKSIGKSQSSSPQKQTSSGTKSRSH 213
           R+ RR++ +R RSRS+S ++ RS+S  +          S  +  R H
Sbjct: 62  RSSRRHY-TRSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRRRH 107



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 11/102 (10%)

Query: 105 SPSDHRRSRSPSQRRTRSRSSSWGR-NRRRSDSLKESRHR-----RFSYSQSKSRSKSLP 158
           S S H   +S      RSRS    R +R +S S  ESR R     R  Y++S+SRS+S  
Sbjct: 20  SGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRS-H 78

Query: 159 RRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSP 200
           RRS S   SR  RR    R       +  R + +G   +  P
Sbjct: 79  RRSRSRSYSRDYRR----RHSHSHSPMSTRRRHVGNRANPDP 116


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 67.8 bits (164), Expect = 9e-12
 Identities = 61/178 (34%), Positives = 89/178 (50%), Gaps = 16/178 (8%)

Query: 90   RKTPGQMKSKERHPCSPS-DHR---RSRSPSQRR---TRSRSSSWGRNRRRSDSLKES-R 141
            RK   + +S+ R   S S  HR   RSRS S+RR   +RSRS S GR     +  K S +
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896

Query: 142  HRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQS---S 198
            HR  S  + + RS S   R T   +SRTP R    R RS + S ++RS+S+G+ +S   S
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSR----RSRSHTPSRRRRSRSVGRRRSFSIS 1952

Query: 199  SPQKQTSSGTKSRSHGRHSDSIA-RSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSY 255
              ++  +   +SR+  R S + + RS   S +  T S      ++    RS  R RS+
Sbjct: 1953 PSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSF 2010



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 52/169 (30%), Positives = 86/169 (50%), Gaps = 5/169 (2%)

Query: 89   DRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYS 148
            ++K    ++S+ +   S S+H+  +  S+ R+R+R  S      RS +   SR RR   S
Sbjct: 1815 EKKRDSSLRSRSKRSKS-SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873

Query: 149  QSKSRSKSLPRRSTS-ARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSG 207
             S+SRSKS  RRS S  ++ R+P+    SR R R +S  + ++   +++S +P +++ S 
Sbjct: 1874 -SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH 1932

Query: 208  TKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYR 256
            T SR   R S S+ R    S      S T  + ++    RS + SR  R
Sbjct: 1933 TPSRR--RRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSR 1979



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 10/163 (6%)

Query: 96   MKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSR-- 153
            +K K+ H  S  +  R +   +++   R SS     +RS S +    +R S S+S++R  
Sbjct: 1794 VKVKDTHEKSKKNKNRDKGEKEKK---RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKR 1850

Query: 154  -SKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRS 212
             SKS   RS +  +SR+ RR   SR RS+S+  +  SK   + +S   + ++    + RS
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE-KRKRSPKHRSKSRERKRKRS 1909

Query: 213  HGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSY 255
              R +    R+  ++P   + S T    ++    RS  R RS+
Sbjct: 1910 SSRDNRKTVRARSRTPSRRSRSHT---PSRRRRSRSVGRRRSF 1949



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 53/137 (38%), Positives = 74/137 (54%), Gaps = 16/137 (11%)

Query: 105  SPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSA 164
            +PS   RS +PS+RR RSRS      RRRS S+  SR  R    +S++ S+   R  T +
Sbjct: 1924 TPSRRSRSHTPSRRR-RSRSVG----RRRSFSISPSRRSRTPSRRSRTPSR---RSRTPS 1975

Query: 165  RQSRTP-RRNFGSRGRSRSKSLQKRSKSI--GKSQSSSPQKQTSSGTK-----SRSHGRH 216
            R+SRTP RR+     RSR+ S ++RS+S+   +S S SP +   S T      SRS  R 
Sbjct: 1976 RRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRR 2035

Query: 217  SDSIARSPCKSPKGYTN 233
              S +    +SPK  T+
Sbjct: 2036 KRSRSSERGRSPKRLTD 2052



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 52/180 (28%), Positives = 82/180 (45%), Gaps = 21/180 (11%)

Query: 90   RKTPGQMKSKERHPCSPSDHRRSRSPSQR---RTRSRSSSWGRNRR---RSDSLKESRHR 143
            R+   + +SK R   S S  +R RSP  R   R R R  S  R+ R   R+ S   SR  
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929

Query: 144  RFSYSQSKSRSKSLPRRST----SARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSS 199
            R      + RS+S+ RR +     +R+SRTP R      RSR+ S + R+ S      S 
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR------RSRTPSRRSRTPSRRSRTPSR 1983

Query: 200  PQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKN 259
              +  S  +++ S  R S S+ R      + ++ S  +++ ++    R  SRS   R ++
Sbjct: 1984 RSRTPSRRSRTPSRRRRSRSVVRR-----RSFSISPVRLRRSRTPLRRRFSRSPIRRKRS 2038



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 44/119 (36%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 79   RQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQR-RTRSRSSSWGRNRRRSDSL 137
            R   I  ++  R    + ++  R   +PS  RRSR+PS+R RT SR S     RRRS S+
Sbjct: 1947 RSFSISPSRRSRTPSRRSRTPSRRSRTPS--RRSRTPSRRSRTPSRRSRTPSRRRRSRSV 2004

Query: 138  KESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQ 196
               R R FS S  + R    P R    R SR+P R   SR   R +S  KR   + K+Q
Sbjct: 2005 --VRRRSFSISPVRLRRSRTPLR---RRFSRSPIRRKRSRSSERGRS-PKRLTDLDKAQ 2057



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 14/112 (12%)

Query: 101  RHPCSPSDHRRSRSPSQR-RTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSR-SKSLP 158
            R   S S  RRSR+PS+R RT SR S     R R+ S +     R S + S+ R S+S+ 
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005

Query: 159  RRSTSA------RQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQT 204
            RR + +      R+SRTP R    R  SRS   +KRS+S    +  SP++ T
Sbjct: 2006 RRRSFSISPVRLRRSRTPLR----RRFSRSPIRRKRSRS--SERGRSPKRLT 2051



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 33/144 (22%)

Query: 117  QRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGS 176
            ++  ++++   G   ++ DS   SR +R   S+ KSR ++   RS + ++S         
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS--------- 1851

Query: 177  RGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSET 236
                 SKS   RS++  +S+S S +++ SS ++S+S GR S S               E 
Sbjct: 1852 -----SKSKSHRSQT--RSRSRSRRRRRSSRSRSKSRGRRSVS--------------KEK 1890

Query: 237  KVQTAKHSHFRSHSRSRSYRHKNS 260
            + ++ KH   RS SR R  +  +S
Sbjct: 1891 RKRSPKH---RSKSRERKRKRSSS 1911


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 67.8 bits (164), Expect = 9e-12
 Identities = 61/178 (34%), Positives = 89/178 (50%), Gaps = 16/178 (8%)

Query: 90   RKTPGQMKSKERHPCSPS-DHR---RSRSPSQRR---TRSRSSSWGRNRRRSDSLKES-R 141
            RK   + +S+ R   S S  HR   RSRS S+RR   +RSRS S GR     +  K S +
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896

Query: 142  HRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQS---S 198
            HR  S  + + RS S   R T   +SRTP R    R RS + S ++RS+S+G+ +S   S
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSR----RSRSHTPSRRRRSRSVGRRRSFSIS 1952

Query: 199  SPQKQTSSGTKSRSHGRHSDSIA-RSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSY 255
              ++  +   +SR+  R S + + RS   S +  T S      ++    RS  R RS+
Sbjct: 1953 PSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSF 2010



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 52/169 (30%), Positives = 86/169 (50%), Gaps = 5/169 (2%)

Query: 89   DRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYS 148
            ++K    ++S+ +   S S+H+  +  S+ R+R+R  S      RS +   SR RR   S
Sbjct: 1815 EKKRDSSLRSRSKRSKS-SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873

Query: 149  QSKSRSKSLPRRSTS-ARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSG 207
             S+SRSKS  RRS S  ++ R+P+    SR R R +S  + ++   +++S +P +++ S 
Sbjct: 1874 -SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH 1932

Query: 208  TKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYR 256
            T SR   R S S+ R    S      S T  + ++    RS + SR  R
Sbjct: 1933 TPSRR--RRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSR 1979



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 10/163 (6%)

Query: 96   MKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSR-- 153
            +K K+ H  S  +  R +   +++   R SS     +RS S +    +R S S+S++R  
Sbjct: 1794 VKVKDTHEKSKKNKNRDKGEKEKK---RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKR 1850

Query: 154  -SKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRS 212
             SKS   RS +  +SR+ RR   SR RS+S+  +  SK   + +S   + ++    + RS
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE-KRKRSPKHRSKSRERKRKRS 1909

Query: 213  HGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSY 255
              R +    R+  ++P   + S T    ++    RS  R RS+
Sbjct: 1910 SSRDNRKTVRARSRTPSRRSRSHT---PSRRRRSRSVGRRRSF 1949



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 53/137 (38%), Positives = 74/137 (54%), Gaps = 16/137 (11%)

Query: 105  SPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSA 164
            +PS   RS +PS+RR RSRS      RRRS S+  SR  R    +S++ S+   R  T +
Sbjct: 1924 TPSRRSRSHTPSRRR-RSRSVG----RRRSFSISPSRRSRTPSRRSRTPSR---RSRTPS 1975

Query: 165  RQSRTP-RRNFGSRGRSRSKSLQKRSKSI--GKSQSSSPQKQTSSGTK-----SRSHGRH 216
            R+SRTP RR+     RSR+ S ++RS+S+   +S S SP +   S T      SRS  R 
Sbjct: 1976 RRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRR 2035

Query: 217  SDSIARSPCKSPKGYTN 233
              S +    +SPK  T+
Sbjct: 2036 KRSRSSERGRSPKRLTD 2052



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 52/180 (28%), Positives = 82/180 (45%), Gaps = 21/180 (11%)

Query: 90   RKTPGQMKSKERHPCSPSDHRRSRSPSQR---RTRSRSSSWGRNRR---RSDSLKESRHR 143
            R+   + +SK R   S S  +R RSP  R   R R R  S  R+ R   R+ S   SR  
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929

Query: 144  RFSYSQSKSRSKSLPRRST----SARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSS 199
            R      + RS+S+ RR +     +R+SRTP R      RSR+ S + R+ S      S 
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR------RSRTPSRRSRTPSRRSRTPSR 1983

Query: 200  PQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKN 259
              +  S  +++ S  R S S+ R      + ++ S  +++ ++    R  SRS   R ++
Sbjct: 1984 RSRTPSRRSRTPSRRRRSRSVVRR-----RSFSISPVRLRRSRTPLRRRFSRSPIRRKRS 2038



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 44/119 (36%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 79   RQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQR-RTRSRSSSWGRNRRRSDSL 137
            R   I  ++  R    + ++  R   +PS  RRSR+PS+R RT SR S     RRRS S+
Sbjct: 1947 RSFSISPSRRSRTPSRRSRTPSRRSRTPS--RRSRTPSRRSRTPSRRSRTPSRRRRSRSV 2004

Query: 138  KESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQ 196
               R R FS S  + R    P R    R SR+P R   SR   R +S  KR   + K+Q
Sbjct: 2005 --VRRRSFSISPVRLRRSRTPLR---RRFSRSPIRRKRSRSSERGRS-PKRLTDLDKAQ 2057



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 14/112 (12%)

Query: 101  RHPCSPSDHRRSRSPSQR-RTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSR-SKSLP 158
            R   S S  RRSR+PS+R RT SR S     R R+ S +     R S + S+ R S+S+ 
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005

Query: 159  RRSTSA------RQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQT 204
            RR + +      R+SRTP R    R  SRS   +KRS+S    +  SP++ T
Sbjct: 2006 RRRSFSISPVRLRRSRTPLR----RRFSRSPIRRKRSRS--SERGRSPKRLT 2051



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 33/144 (22%)

Query: 117  QRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGS 176
            ++  ++++   G   ++ DS   SR +R   S+ KSR ++   RS + ++S         
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS--------- 1851

Query: 177  RGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSET 236
                 SKS   RS++  +S+S S +++ SS ++S+S GR S S               E 
Sbjct: 1852 -----SKSKSHRSQT--RSRSRSRRRRRSSRSRSKSRGRRSVS--------------KEK 1890

Query: 237  KVQTAKHSHFRSHSRSRSYRHKNS 260
            + ++ KH   RS SR R  +  +S
Sbjct: 1891 RKRSPKH---RSKSRERKRKRSSS 1911


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 59/169 (34%), Positives = 79/169 (46%), Gaps = 27/169 (15%)

Query: 93  PGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKS 152
           P + + K RH  S S  RR R+PS  R R       R+R RS        RR S+S+S+S
Sbjct: 239 PDKKEEKRRHSRSRSRSRRRRTPSSSRHR-------RSRSRS--------RRRSHSKSRS 283

Query: 153 RSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRS 212
           R     RRS S R+ R+  R  G R RS SK+  K+ +   K +S +P K  S+  +SRS
Sbjct: 284 R-----RRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRS 338

Query: 213 -----HGRHSDSIARSPCK--SPKGYTNSETKVQTAKHSHFRSHSRSRS 254
                  R S S  RSP K  SPK   +     +  K    +   + RS
Sbjct: 339 ASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387



 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 53/174 (30%), Positives = 90/174 (51%), Gaps = 21/174 (12%)

Query: 90  RKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESR---HRRFS 146
           R +  + +S+ R   S S HRRSRS S+RR+ S+S    R+RRRS S +  R     R  
Sbjct: 247 RHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKS----RSRRRSKSPRRRRSHSRERGR 302

Query: 147 YSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSS 206
            S+S S+++   +     ++S+TP +++ +  RSRS S ++R +   +S + SP+K  S 
Sbjct: 303 RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRR-SRSGTRSPKKPRSP 361

Query: 207 GTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSH-FRSHSRSRSYRHKN 259
             K          ++RSP  SP+ +   + K +  + S   R  S S+  + K+
Sbjct: 362 KRK----------LSRSP--SPRRHKKEKKKDKDKERSRDERERSTSKKKKSKD 403



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKS 156
           K K+R    P  +  +R       RSRS+S  R RRRS S   S  +  S  +  SRS S
Sbjct: 318 KEKKRSKTPPKSYSTAR-------RSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPS 370

Query: 157 LPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTK 209
             R     ++ +   R+   R RS SK  + + K   + + S   K     T+
Sbjct: 371 PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTR 423



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 7/105 (6%)

Query: 90  RKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQ 149
           +K   + K  +  P S S  RRSRS S+ R R RS S  R+ ++  S K    R+ S S 
Sbjct: 314 KKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPK----RKLSRSP 369

Query: 150 SKSRSKSLPRRSTSARQSRTPRRNFGSR---GRSRSKSLQKRSKS 191
           S  R K   ++     +SR  R    S+    + + K  +++S+S
Sbjct: 370 SPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES 414



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 13/120 (10%)

Query: 154 SKSLPRRSTSARQSRTPRRNFGSRGRSR-------SKSLQKRSKSIGKSQSSSPQKQTSS 206
           ++SL   +    +    RR+  SR RSR       S+  + RS+S  +S S S  ++ S 
Sbjct: 229 AQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSK 288

Query: 207 GTK-----SRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHF-RSHSRSRSYRHKNS 260
             +     SR  GR S S +++  K  +      +K     +S   RS S SR  R + S
Sbjct: 289 SPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRS 348



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 1/80 (1%)

Query: 182 SKSLQKRSKSIGKSQSS-SPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQT 240
           SK +++  K + ++QS  S   +     + R H R      R    S   +  S ++ + 
Sbjct: 216 SKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRR 275

Query: 241 AKHSHFRSHSRSRSYRHKNS 260
             HS  RS  RS+S R + S
Sbjct: 276 RSHSKSRSRRRSKSPRRRRS 295


>gi|9558733 transformer-2 alpha [Homo sapiens]
          Length = 282

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 60/176 (34%), Positives = 82/176 (46%), Gaps = 22/176 (12%)

Query: 2   SRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDV 61
           SR    PNT L +  ++  T   DLR  F RYGP+  V +  D  T R RGFA+V FE +
Sbjct: 111 SRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERI 170

Query: 62  RDAEDALYNLNRKWVCGRQIEIQFA---QGDRKTPGQMKSKERHP----------CSPSD 108
            D+++A+   N   + GR+I + ++   +    TPG    +  H                
Sbjct: 171 DDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGG 230

Query: 109 HRRSRSPSQR---RTRSRSSSWG-RNRRRSDSLKESRHRRFSYSQSKSRSKSLPRR 160
            RR  S   R   R   R   +  R RRRS S   SR+R    S+S+SRS S PRR
Sbjct: 231 GRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYR----SRSRSRSYS-PRR 281



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 36/103 (34%), Positives = 51/103 (49%), Gaps = 3/103 (2%)

Query: 111 RSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTP 170
           RS+S S   T +R  S  R+  RS S         S S+SKSRS+S  RR +  R +R+ 
Sbjct: 15  RSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRS--RRHSHRRYTRSR 72

Query: 171 RRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSH 213
             +   R RSRS+S     +   +S+S SP       T SR++
Sbjct: 73  SHSHSHRRRSRSRSYTPEYRR-RRSRSHSPMSNRRRHTGSRAN 114



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 42/114 (36%), Positives = 55/114 (48%), Gaps = 25/114 (21%)

Query: 92  TPGQMKSKERH----PCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSY 147
           TP ++KS+ R     P   S H  S S S+ ++RSRS      RR S       HRR  Y
Sbjct: 24  TPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRS------RRHS-------HRR--Y 68

Query: 148 SQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKS-LQKRSKSIGKSQSSSP 200
           ++S+S S S  RRS S  +S TP      R RSRS S +  R +  G   +  P
Sbjct: 69  TRSRSHSHSHRRRSRS--RSYTPEYR---RRRSRSHSPMSNRRRHTGSRANPDP 117



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 27/136 (19%)

Query: 134 SDSLKESRHRRFSYSQSKSRSKSLPR-RSTSARQSRTPRR-----NFGSRGRSRSKSLQK 187
           SD  + +   R S SQSKS + +  R +S S   SR+P R        SR RS+S+S   
Sbjct: 2   SDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRS--- 58

Query: 188 RSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKH---S 244
                 +S+  S ++ T S + S SH R S S         + YT    + ++  H   S
Sbjct: 59  ------RSRRHSHRRYTRSRSHSHSHRRRSRS---------RSYTPEYRRRRSRSHSPMS 103

Query: 245 HFRSHSRSRSYRHKNS 260
           + R H+ SR+    N+
Sbjct: 104 NRRRHTGSRANPDPNT 119


>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
          Length = 391

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 66/265 (24%), Positives = 102/265 (38%), Gaps = 23/265 (8%)

Query: 12  LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
           LFI  +   T  + L   FG+YG IV+V +  D  T + RGFA+V FE   DA+DA  ++
Sbjct: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69

Query: 72  NRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWG-RN 130
           N K + G+ I+++ A     T    +S  R P  P    RSR P +     R  S G R 
Sbjct: 70  NGKSLDGKAIKVEQA-----TKPSFESGRRGPPPPP---RSRGPPRGLRGGRGGSGGTRG 121

Query: 131 RRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSK 190
                   +      +++ S SR     +R    R    P +     G  RS S      
Sbjct: 122 PPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVRSSSGMGGRA 181

Query: 191 SIGKSQSS---SPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAK----- 242
            + + + S    P+++     +        D  +     S + Y +S      A      
Sbjct: 182 PVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDY 241

Query: 243 ------HSHFRSHSRSRSYRHKNSW 261
                 HS  R    SR Y  ++ +
Sbjct: 242 TYRDYGHSSSRDDYPSRGYSDRDGY 266


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 64/192 (33%), Positives = 91/192 (47%), Gaps = 37/192 (19%)

Query: 86   AQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRF 145
            A+ +R+   Q  S +    S  D  +SRSPS  R+RS+S +  R+R RS           
Sbjct: 1285 ARLNRRPRNQESSSDEQTPSRDDDSQSRSPS--RSRSKSETKSRHRTRS----------V 1332

Query: 146  SYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKR--------SKSIGKSQS 197
            SYS S+SRS+S      S   SR+  R + SRGR+RS+S   R        S+S  +S S
Sbjct: 1333 SYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSS 1392

Query: 198  SSPQKQTSSGT--------KSRSHGRHSDSIARS-----PCKSPKGY-TNSETKVQTAKH 243
              P  ++ S T        +SRS  + SDS  R        +S + Y ++SE+      +
Sbjct: 1393 YDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSES---DRSY 1449

Query: 244  SHFRSHSRSRSY 255
            SH RS S S  Y
Sbjct: 1450 SHHRSPSESSRY 1461



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 56/166 (33%), Positives = 80/166 (48%), Gaps = 15/166 (9%)

Query: 95   QMKSKER-HPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSR 153
            ++KSK +  P S  D  R  +   RR R++ SS        D   +SR    S S+S+S+
Sbjct: 1265 EIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSR----SPSRSRSK 1320

Query: 154  SKSLPR---RSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKS 210
            S++  R   RS S   SR+  R+  S  RSRS S   RS+S G       + ++SS    
Sbjct: 1321 SETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYS---RSRSRGWYSRGRTRSRSSSYRSY 1377

Query: 211  RSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYR 256
            +SH   S S +RS    P    +S ++  T    + RS SRSRS R
Sbjct: 1378 KSHRTSSRSRSRSSSYDP----HSRSRSYTYDSYYSRSRSRSRSQR 1419



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 45/140 (32%), Positives = 71/140 (50%), Gaps = 15/140 (10%)

Query: 129  RNRRRSDSL-----KESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSK 183
            +N+ R  SL     K +R  R   +Q  S  +  P R   + QSR+P R   SR +S +K
Sbjct: 1269 KNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDS-QSRSPSR---SRSKSETK 1324

Query: 184  SLQKR-----SKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKV 238
            S  +      S S  +S+SS+   ++ S ++SRS G +S    RS   S + Y +  T  
Sbjct: 1325 SRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSS 1384

Query: 239  QT-AKHSHFRSHSRSRSYRH 257
            ++ ++ S +  HSRSRSY +
Sbjct: 1385 RSRSRSSSYDPHSRSRSYTY 1404



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 42/172 (24%), Positives = 66/172 (38%), Gaps = 1/172 (0%)

Query: 86  AQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRF 145
           ++ D+ T  +   +       S  R SRS S  R+ +RS S   +  RS S     H R 
Sbjct: 671 SESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRN 730

Query: 146 SYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTS 205
            YS     S+S    S S+   R  +R   S G+  S S +K S S  K+  S   K   
Sbjct: 731 KYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRD 790

Query: 206 SGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHF-RSHSRSRSYR 256
             +  R +     S+  S          +++  +  K     R+H++    R
Sbjct: 791 RSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR 842



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 53/176 (30%), Positives = 82/176 (46%), Gaps = 33/176 (18%)

Query: 105 SPSDHRRSR-SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRF---SYSQSKSRSKSLPRR 160
           S S H+R + S S + T S+ S      R S+S   SR R     SYS+S +RS+SL   
Sbjct: 661 SSSYHKREKNSESDQSTYSKYSD-----RSSESSPRSRSRSSRSRSYSRSYTRSRSL--- 712

Query: 161 STSARQSRTPRRNFGSRGR-------SRSKS-----------LQKRSKSIGKSQSSSPQK 202
           ++S  +SR+P     SR +       SRS S            ++R +S GK  S S +K
Sbjct: 713 ASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKK 772

Query: 203 QTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHK 258
            +SS  K+  H ++     RS C   + Y+ S + +  +  S   S   ++S + K
Sbjct: 773 HSSSSEKT-LHSKYVKGRDRSSC--VRKYSESRSSLDYSSDSEQSSVQATQSAQEK 825



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 55/196 (28%), Positives = 78/196 (39%), Gaps = 31/196 (15%)

Query: 82  EIQFAQGDRKTPGQMKSKE---RHPCSPSDHRRSRSPSQRR----------TRSRSSSWG 128
           E+Q  +  R   G+  SK      PCS     RS S   R           + +R S   
Sbjct: 368 EMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHH 427

Query: 129 RNRRRSDSLK------ESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRS-R 181
           + RR+   +K      + +H R  + Q+K R   +P    S++ S    ++   R RS R
Sbjct: 428 KKRRKEKKVKHKKKGKKQKHCR-RHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSR 486

Query: 182 SKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGR---HSDSIARSPCKSPKGYTNSETKV 238
           S SL     S      S    Q+S    SR   R   HS S +R       G + S T  
Sbjct: 487 SSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSR-------GSSRSRTAS 539

Query: 239 QTAKHSHFRSHSRSRS 254
           +++ HS  RS SRS S
Sbjct: 540 KSSSHSRSRSKSRSSS 555



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/121 (33%), Positives = 61/121 (50%), Gaps = 15/121 (12%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRR-RSDSLKESRHRRFSYSQS-KSRS 154
           ++K+R    PSD   S+S     TR   SS  R R  RS SL      +  +S+S K   
Sbjct: 453 QTKKRRILIPSDIESSKSS----TRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQ 508

Query: 155 KSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQK---RSKSIGKSQSSSPQKQTSSGTKSR 211
            SL   S  + +S++  +++ SRG SRS++  K    S+S  KS+SSS      SG + R
Sbjct: 509 SSLTHSSRDSYRSKSHSQSY-SRGSSRSRTASKSSSHSRSRSKSRSSS-----KSGHRKR 562

Query: 212 S 212
           +
Sbjct: 563 A 563



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 12/115 (10%)

Query: 105 SPSDHRRSRSPSQRRTRSRSSSWG------RNRRRSDSLKESR--HRRFSYSQSKSRSKS 156
           S S  RR +S   R   SRSSS        R+  +SD   +S   H      +SKS S+S
Sbjct: 468 SKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQS 527

Query: 157 LPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSR 211
             R S+   +SRT  ++  S  RSRSKS         K  S SP+K  S  ++++
Sbjct: 528 YSRGSS---RSRTASKS-SSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENK 578



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 57/233 (24%), Positives = 89/233 (38%), Gaps = 56/233 (24%)

Query: 85  FAQGDRKTPGQMKSKERHPCSPSDHRRS--RSPSQRRTRSRSSSWGRNRRRSDSLKESRH 142
           +++ D+     +    R       H +S  R  S+ RT S+SSS  R+R +S S  +S H
Sbjct: 500 WSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGH 559

Query: 143 R-RFSYSQSKSRS--------KSLPRRSTSARQ------------------SRTPRRNFG 175
           R R S S  K+ S        K+ P R+T A+                   S +P  +  
Sbjct: 560 RKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRW 619

Query: 176 SRGRSRSKSLQKR----------------------SKSIGKSQSSSPQKQTS---SGTKS 210
             G+   K   +R                       K  G S S   +++ S     T S
Sbjct: 620 KPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYS 679

Query: 211 RSHGRHSDSIARSPCKS--PKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNSW 261
           +   R S+S  RS  +S   + Y+ S T+ ++   SH RS S S     +N +
Sbjct: 680 KYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKY 732



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 11/117 (9%)

Query: 148 SQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQ------SSSPQ 201
           S S    +     S  +  S+   R+  S  RSRS+S   RS+S  +S       +SS  
Sbjct: 660 SSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRS--SRSRSYSRSYTRSRSLASSHS 717

Query: 202 KQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHK 258
           +  S  ++S S  ++SD    S C     YT+  +          RS  +  S  HK
Sbjct: 718 RSRSPSSRSHSRNKYSD---HSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHK 771



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 3/120 (2%)

Query: 96  MKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSR-- 153
           +K ++R  C    +  SRS     + S  SS    +   +  K+ +  R    Q K+R  
Sbjct: 786 VKGRDRSSCVRK-YSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGE 844

Query: 154 SKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSH 213
            KS   R     + RT + N     R+ SK  +K          S+ ++  +  +K+ SH
Sbjct: 845 EKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSH 904



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 11/68 (16%)

Query: 194  KSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSR 253
            ++Q SS  +QT S        R  DS +RSP +S    + SETK +    S   SHSRSR
Sbjct: 1292 RNQESSSDEQTPS--------RDDDSQSRSPSRSR---SKSETKSRHRTRSVSYSHSRSR 1340

Query: 254  SYRHKNSW 261
            S    +S+
Sbjct: 1341 SRSSTSSY 1348



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 6/82 (7%)

Query: 138 KESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQS 197
           K+  H   S S S S S S     +     R+ RR    R +       KRSK   K  S
Sbjct: 190 KKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKV------KRSKKRRKEAS 243

Query: 198 SSPQKQTSSGTKSRSHGRHSDS 219
           SS + +       + H   SD+
Sbjct: 244 SSEEPRNKHAMNPKGHSERSDT 265



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 50/196 (25%), Positives = 74/196 (37%), Gaps = 43/196 (21%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRSRSS------------SWGRNRR------------ 132
           +SK R   S S HR+  S S R+T S+ S            +  +N              
Sbjct: 548 RSKSRSS-SKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIP 606

Query: 133 ---RSDSLKESRHR--RFSYSQSKSRSKSLPRRSTSAR--QSRTPRRNFGSRGRSRS-KS 184
               SDS   SR +  +  +  S  R + +  ++T     QS     N    G S S   
Sbjct: 607 VIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHK 666

Query: 185 LQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHS 244
            +K S+S   + S    + + S  +SRS    S S +RS       YT S +   +   S
Sbjct: 667 REKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRS-------YTRSRSLASSHSRS 719

Query: 245 H---FRSHSRSRSYRH 257
                RSHSR++   H
Sbjct: 720 RSPSSRSHSRNKYSDH 735



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 27/132 (20%), Positives = 55/132 (41%), Gaps = 20/132 (15%)

Query: 109 HRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQS- 167
           H++  S S++   S+   + + R RS  +++    R S   S    +S  + + SA++  
Sbjct: 770 HKKHSSSSEKTLHSK---YVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKE 826

Query: 168 ------RTPRRNFGSRGRSRSKSLQ----------KRSKSIGKSQSSSPQKQTSSGTKSR 211
                 RT  +   +RG  +SKS +          K + S      S P+++  +G+K  
Sbjct: 827 KQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWD 886

Query: 212 SHGRHSDSIARS 223
           S       + ++
Sbjct: 887 SESNSERDVTKN 898


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 10/149 (6%)

Query: 89  DRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYS 148
           DR+   + +S+ RH    SD R SRS   +R+RS      R RRRS S    R R    S
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS------RERRRSRSRDRRRSRSHDRS 339

Query: 149 QSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGT 208
           + K RS+S  RR + +R     R+++  R +SR +   ++SK   K  S   +    SG+
Sbjct: 340 ERKHRSRSRDRRRSKSRD----RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395

Query: 209 KSRSHGRHSDSIARSPCKSPKGYTNSETK 237
           + +     +     S  K+    T+ + K
Sbjct: 396 REKQSEDTNTESKESDTKNEVNGTSEDIK 424



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 1/149 (0%)

Query: 95  QMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRS 154
           + + K R      +  R+R   +RR RSRS S   +R        SR  + S S+ + RS
Sbjct: 267 ERERKRRREEEEREKERARD-RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRS 325

Query: 155 KSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHG 214
           +S  RR + +      +    SR R RSKS  ++S           Q + S   + R   
Sbjct: 326 RSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385

Query: 215 RHSDSIARSPCKSPKGYTNSETKVQTAKH 243
               S+     +     TN+E+K    K+
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESDTKN 414



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 29/168 (17%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKS 156
           K ++R      D R  +   +R  R +     R R R +  +E + RR    + K R++ 
Sbjct: 233 KLRKRTEEPDRDERLKKEKQEREEREKE----REREREE--RERKRRREEEEREKERARD 286

Query: 157 LPRRSTSARQSR-----TPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSR 211
             RR  S  +SR     + RR   SR   RS+S ++R     +S+S   ++  S     R
Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR-----RSRSRDRRRSRSHDRSER 341

Query: 212 SHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKN 259
            H   S    RS  +  K Y          KH   RS SR R    K+
Sbjct: 342 KHRSRSRDRRRSKSRDRKSY----------KH---RSKSRDREQDRKS 376



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 13/166 (7%)

Query: 99  KERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLP 158
           KE+      +  R R   +R  + R     R + R+   ++   R+ S S+S+  S++  
Sbjct: 249 KEKQEREEREKEREREREERERKRRREEEEREKERA---RDRERRKRSRSRSRHSSRTSD 305

Query: 159 RRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQ----SSSPQKQTSSGTKSRSHG 214
           RR + +R  +  R     R RSRS+  ++RS+S  +S+    S S  ++ S     +S+ 
Sbjct: 306 RRCSRSRDHKRSRSR--ERRRSRSRD-RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362

Query: 215 RHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
             S S  R   +  K     E +    K S  +S SR +     N+
Sbjct: 363 HRSKSRDREQDRKSK---EKEKRGSDDKKSSVKSGSREKQSEDTNT 405


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 10/149 (6%)

Query: 89  DRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYS 148
           DR+   + +S+ RH    SD R SRS   +R+RS      R RRRS S    R R    S
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS------RERRRSRSRDRRRSRSHDRS 339

Query: 149 QSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGT 208
           + K RS+S  RR + +R     R+++  R +SR +   ++SK   K  S   +    SG+
Sbjct: 340 ERKHRSRSRDRRRSKSRD----RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395

Query: 209 KSRSHGRHSDSIARSPCKSPKGYTNSETK 237
           + +     +     S  K+    T+ + K
Sbjct: 396 REKQSEDTNTESKESDTKNEVNGTSEDIK 424



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 1/149 (0%)

Query: 95  QMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRS 154
           + + K R      +  R+R   +RR RSRS S   +R        SR  + S S+ + RS
Sbjct: 267 ERERKRRREEEEREKERARD-RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRS 325

Query: 155 KSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHG 214
           +S  RR + +      +    SR R RSKS  ++S           Q + S   + R   
Sbjct: 326 RSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385

Query: 215 RHSDSIARSPCKSPKGYTNSETKVQTAKH 243
               S+     +     TN+E+K    K+
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESDTKN 414



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 29/168 (17%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKS 156
           K ++R      D R  +   +R  R +     R R R +  +E + RR    + K R++ 
Sbjct: 233 KLRKRTEEPDRDERLKKEKQEREEREKE----REREREE--RERKRRREEEEREKERARD 286

Query: 157 LPRRSTSARQSR-----TPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSR 211
             RR  S  +SR     + RR   SR   RS+S ++R     +S+S   ++  S     R
Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR-----RSRSRDRRRSRSHDRSER 341

Query: 212 SHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKN 259
            H   S    RS  +  K Y          KH   RS SR R    K+
Sbjct: 342 KHRSRSRDRRRSKSRDRKSY----------KH---RSKSRDREQDRKS 376



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 13/166 (7%)

Query: 99  KERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLP 158
           KE+      +  R R   +R  + R     R + R+   ++   R+ S S+S+  S++  
Sbjct: 249 KEKQEREEREKEREREREERERKRRREEEEREKERA---RDRERRKRSRSRSRHSSRTSD 305

Query: 159 RRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQ----SSSPQKQTSSGTKSRSHG 214
           RR + +R  +  R     R RSRS+  ++RS+S  +S+    S S  ++ S     +S+ 
Sbjct: 306 RRCSRSRDHKRSRSR--ERRRSRSRD-RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362

Query: 215 RHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHKNS 260
             S S  R   +  K     E +    K S  +S SR +     N+
Sbjct: 363 HRSKSRDREQDRKSK---EKEKRGSDDKKSSVKSGSREKQSEDTNT 405


>gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo
           sapiens]
          Length = 390

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 58/200 (29%), Positives = 83/200 (41%), Gaps = 13/200 (6%)

Query: 12  LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
           LFI  +   T  + L   FG+YG IV+V +  D  T + RGFA+V FE   DA+DA  ++
Sbjct: 10  LFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARDM 69

Query: 72  NRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNR 131
           N K + G+ I+++ A           S ER    P    RSR P +     R  S G   
Sbjct: 70  NGKSLDGKAIKVEQA--------TKPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGG--- 118

Query: 132 RRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKS 191
            R    +        YS + + S S  R     ++   PR    S  RS    L + S  
Sbjct: 119 TRGPPSRGGHMDDGGYSMNFNMSSS--RGPLPVKRGPPPRSGGPSPKRSAPSGLVRSSSG 176

Query: 192 IGKSQSSSPQKQTSSGTKSR 211
           +G     S  + +  G   R
Sbjct: 177 MGGRAPLSRGRDSYGGPPRR 196


>gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo
           sapiens]
          Length = 390

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 58/200 (29%), Positives = 83/200 (41%), Gaps = 13/200 (6%)

Query: 12  LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
           LFI  +   T  + L   FG+YG IV+V +  D  T + RGFA+V FE   DA+DA  ++
Sbjct: 10  LFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARDM 69

Query: 72  NRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNR 131
           N K + G+ I+++ A           S ER    P    RSR P +     R  S G   
Sbjct: 70  NGKSLDGKAIKVEQA--------TKPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGG--- 118

Query: 132 RRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKS 191
            R    +        YS + + S S  R     ++   PR    S  RS    L + S  
Sbjct: 119 TRGPPSRGGHMDDGGYSMNFNMSSS--RGPLPVKRGPPPRSGGPSPKRSAPSGLVRSSSG 176

Query: 192 IGKSQSSSPQKQTSSGTKSR 211
           +G     S  + +  G   R
Sbjct: 177 MGGRAPLSRGRDSYGGPPRR 196


>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
           sapiens]
          Length = 747

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 52/157 (33%), Positives = 73/157 (46%), Gaps = 24/157 (15%)

Query: 105 SPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRR-STS 163
           S S   RS+S SQ  +RSRS S  R +R S     SR R  +YS+S+SR +   R     
Sbjct: 6   SRSHSSRSKSRSQSSSRSRSRSHSRKKRYS-----SRSRSRTYSRSRSRDRMYSRDYRRD 60

Query: 164 ARQSRTPRRNFGSRGRSRS------------------KSLQKRSKSIGKSQSSSPQKQTS 205
            R +R  RR +G RGR R                        RS   G+S+S SP++++ 
Sbjct: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120

Query: 206 SGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAK 242
           S  +SRS  R S   +RSP  S    ++  +K   +K
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSK 157



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 13/128 (10%)

Query: 109 HRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSR 168
           HR    P   R  SRS   GR+R RS        +R S S  +SRS+S  RR  S R SR
Sbjct: 89  HRGGYRPVWNRRHSRSPRRGRSRSRSP-------KRRSVSSQRSRSRS--RR--SYRSSR 137

Query: 169 TPRRNFGSRGRSRSKS--LQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCK 226
           +PR +        SKS   ++R     +++ +  + Q  S  KS+S     D+    P +
Sbjct: 138 SPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSE 197

Query: 227 SPKGYTNS 234
           S   +  S
Sbjct: 198 SIDEFNKS 205



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 53/177 (29%), Positives = 70/177 (39%), Gaps = 27/177 (15%)

Query: 101 RHPCSPSDHR-RSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLP- 158
           RH  SP   R RSRSP +RR+ S   S  R+RR   S + SR  R S S+S S     P 
Sbjct: 100 RHSRSPRRGRSRSRSP-KRRSVSSQRSRSRSRR---SYRSSRSPRSSSSRSSSPYSKSPV 155

Query: 159 --RRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKS------ 210
             RR +  +Q++            +SKS ++   +     S S  +   S   S      
Sbjct: 156 SKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPG 215

Query: 211 ------RSHGRHSDS-IARSPCKS------PKGYTNSETKVQTAKHSHFRSHSRSRS 254
                      HS S IA  P +S      P   T    K   ++HSH   HS  RS
Sbjct: 216 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS 272



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 17/163 (10%)

Query: 97  KSKERHPC---SPSDHRR-SRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKS 152
           K+ E H     SP  HRR   SPS  R  +R +   R  +  +   + + R  S      
Sbjct: 464 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 523

Query: 153 RSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRS 212
             +    RS     S+  R + GSR + ++    K  KS          K  S   + + 
Sbjct: 524 IDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY---------KDDSKHKREQD 574

Query: 213 HGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSY 255
           H R S S A SP  SP      E+K +  +   F++H   + Y
Sbjct: 575 HSRSSSSSA-SP-SSPSSREEKESKKE--REEEFKTHHEMKEY 613



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 12/79 (15%)

Query: 178 GRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETK 237
           GRS S+S   RSKS         + Q+SS ++SRSH R     +RS  ++   Y+ S ++
Sbjct: 2   GRSNSRSHSSRSKS---------RSQSSSRSRSRSHSRKKRYSSRSRSRT---YSRSRSR 49

Query: 238 VQTAKHSHFRSHSRSRSYR 256
            +     + R +  +R  R
Sbjct: 50  DRMYSRDYRRDYRNNRGMR 68


>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 920

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 52/157 (33%), Positives = 73/157 (46%), Gaps = 24/157 (15%)

Query: 105 SPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRR-STS 163
           S S   RS+S SQ  +RSRS S  R +R S     SR R  +YS+S+SR +   R     
Sbjct: 6   SRSHSSRSKSRSQSSSRSRSRSHSRKKRYS-----SRSRSRTYSRSRSRDRMYSRDYRRD 60

Query: 164 ARQSRTPRRNFGSRGRSRS------------------KSLQKRSKSIGKSQSSSPQKQTS 205
            R +R  RR +G RGR R                        RS   G+S+S SP++++ 
Sbjct: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120

Query: 206 SGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAK 242
           S  +SRS  R S   +RSP  S    ++  +K   +K
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSK 157



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 13/128 (10%)

Query: 109 HRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSR 168
           HR    P   R  SRS   GR+R RS        +R S S  +SRS+S  RR  S R SR
Sbjct: 89  HRGGYRPVWNRRHSRSPRRGRSRSRSP-------KRRSVSSQRSRSRS--RR--SYRSSR 137

Query: 169 TPRRNFGSRGRSRSKS--LQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCK 226
           +PR +        SKS   ++R     +++ +  + Q  S  KS+S     D+    P +
Sbjct: 138 SPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSE 197

Query: 227 SPKGYTNS 234
           S   +  S
Sbjct: 198 SIDEFNKS 205



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 53/177 (29%), Positives = 70/177 (39%), Gaps = 27/177 (15%)

Query: 101 RHPCSPSDHR-RSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLP- 158
           RH  SP   R RSRSP +RR+ S   S  R+RR   S + SR  R S S+S S     P 
Sbjct: 100 RHSRSPRRGRSRSRSP-KRRSVSSQRSRSRSRR---SYRSSRSPRSSSSRSSSPYSKSPV 155

Query: 159 --RRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKS------ 210
             RR +  +Q++            +SKS ++   +     S S  +   S   S      
Sbjct: 156 SKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPG 215

Query: 211 ------RSHGRHSDS-IARSPCKS------PKGYTNSETKVQTAKHSHFRSHSRSRS 254
                      HS S IA  P +S      P   T    K   ++HSH   HS  RS
Sbjct: 216 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS 272



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 17/163 (10%)

Query: 97  KSKERHPC---SPSDHRR-SRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKS 152
           K+ E H     SP  HRR   SPS  R  +R +   R  +  +   + + R  S      
Sbjct: 637 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 696

Query: 153 RSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRS 212
             +    RS     S+  R + GSR + ++    K  KS          K  S   + + 
Sbjct: 697 IDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY---------KDDSKHKREQD 747

Query: 213 HGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSY 255
           H R S S A SP  SP      E+K +  +   F++H   + Y
Sbjct: 748 HSRSSSSSA-SP-SSPSSREEKESKKE--REEEFKTHHEMKEY 786



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 12/79 (15%)

Query: 178 GRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETK 237
           GRS S+S   RSKS         + Q+SS ++SRSH R     +RS  ++   Y+ S ++
Sbjct: 2   GRSNSRSHSSRSKS---------RSQSSSRSRSRSHSRKKRYSSRSRSRT---YSRSRSR 49

Query: 238 VQTAKHSHFRSHSRSRSYR 256
            +     + R +  +R  R
Sbjct: 50  DRMYSRDYRRDYRNNRGMR 68


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 53/161 (32%), Positives = 77/161 (47%), Gaps = 15/161 (9%)

Query: 59  EDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQR 118
           ED  DA+ + YNL+       + +    + +R++  + KS+  H  S S   RS SPS  
Sbjct: 173 EDEDDADLSKYNLD----ASEEEDSNKKKSNRRS--RSKSRSSHSRSSS---RSSSPSSS 223

Query: 119 RTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRG 178
           R+RSRS      R RS S  +SR R  S  +S+SR       S S R S +PR+   S  
Sbjct: 224 RSRSRS------RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSS 277

Query: 179 RSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDS 219
            S  +  +KRS+S   S     +++T S +  R H   S S
Sbjct: 278 SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 60/161 (37%), Positives = 75/161 (46%), Gaps = 19/161 (11%)

Query: 98  SKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSL 157
           S+E        +RRSRS S R + SRSSS   +   S S   SR R  S SQS+SRS S 
Sbjct: 188 SEEEDSNKKKSNRRSRSKS-RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246

Query: 158 PRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHS 217
            R  +   +SR+      SR    S S +KRS S   S SSSP++      + RS  R S
Sbjct: 247 ERSRSRGSKSRS-----SSRSHRGSSSPRKRSYS---SSSSSPER-----NRKRSRSRSS 293

Query: 218 DSIARSPCKSPKGYTNSETKVQTAKHSHFRSHSRSRSYRHK 258
            S  R      K  T S +  +  + S   SHS SRS   K
Sbjct: 294 SSGDRK-----KRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 9/107 (8%)

Query: 97  KSKERHPCSPSDHRRSRSPSQRRTRSR-----SSSWGRNRRRSDSLKESRHRRFSYSQSK 151
           +S+ R   S S   RSRS S+ R+RSR     SSS  R+ R S S ++  +   S S  +
Sbjct: 226 RSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS--RSHRGSSSPRKRSYSSSSSSPER 283

Query: 152 SRSKSLPRRSTSA--RQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQ 196
           +R +S  R S+S   ++ RT  R+   R RS S S    S+S  K +
Sbjct: 284 NRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 42/126 (33%), Positives = 63/126 (50%), Gaps = 13/126 (10%)

Query: 135 DSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN------FGSRGRSRSKSLQKR 188
           D    S++   +  +  S  K   RRS S  +S   R +        SR RSRS+S +  
Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS-RSS 234

Query: 189 SKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKHSHFRS 248
           S S  +S+SSS ++  S G+KSRS  R S   + SP K  + Y++S +   + + +  RS
Sbjct: 235 SSSQSRSRSSSRERSRSRGSKSRSSSR-SHRGSSSPRK--RSYSSSSS---SPERNRKRS 288

Query: 249 HSRSRS 254
            SRS S
Sbjct: 289 RSRSSS 294



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 9/100 (9%)

Query: 163 SARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSI-A 221
           ++ +  + ++    R RS+S+S   RS     S+SSSP   +SS ++SRS  R S S  +
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRS----SSRSSSP---SSSRSRSRSRSRSSSSSQS 239

Query: 222 RSPCKSPKGYTNSETKVQTAKHSHFRSHS-RSRSYRHKNS 260
           RS   S +   +  +K +++  SH  S S R RSY   +S
Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS 279


>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
           protein [Homo sapiens]
          Length = 1463

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 50/151 (33%), Positives = 79/151 (52%), Gaps = 15/151 (9%)

Query: 105 SPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSA 164
           +P + +R +SPS RR   + S   +++  S   + +R R+ S SQS  +  +  RR +  
Sbjct: 807 TPQEKKRPQSPSPRRETGKESR--KSQSPSPKNESARGRKKSRSQSPKKDIARERRQS-- 862

Query: 165 RQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQ-KQTSSGTKSRSHGRHSDSIARS 223
            QSR+P+R+     R RS+SL  R ++  +++ S P+ K +S G KSRS  R  +     
Sbjct: 863 -QSRSPKRDTTRESR-RSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERE----- 915

Query: 224 PCKSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
              S +     E + +T K S  RSHSRS S
Sbjct: 916 ---SDRDGQRRERERRTRKWSRSRSHSRSPS 943



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 45/142 (31%), Positives = 60/142 (42%), Gaps = 16/142 (11%)

Query: 94  GQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQS--- 150
           G+ KS+ + P    D  R R  SQ R+  R ++  R  RRS+SL   R       +S   
Sbjct: 842 GRKKSRSQSP--KKDIARERRQSQSRSPKRDTT--RESRRSESLSPRRETSRENKRSQPR 897

Query: 151 --------KSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQK 202
                   KSRS+S  R S    Q R   R      RSRS S +  S+   KS+SSS  +
Sbjct: 898 VKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHS-RSPSRCRTKSKSSSFGR 956

Query: 203 QTSSGTKSRSHGRHSDSIARSP 224
                   R  GR ++   R P
Sbjct: 957 IDRDSYSPRWKGRWANDGWRCP 978



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 10/125 (8%)

Query: 90   RKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQ 149
            R+T  + K  +      S   +SRS S+ R   R    G+ R R     E R R++S S+
Sbjct: 885  RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRD---GQRRER-----ERRTRKWSRSR 936

Query: 150  SKSRSKSLPR-RSTSARQSRTPRRNFGSRGRSR-SKSLQKRSKSIGKSQSSSPQKQTSSG 207
            S SRS S  R +S S+   R  R ++  R + R +    +  +   + + + P+KQ  + 
Sbjct: 937  SHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENT 996

Query: 208  TKSRS 212
             K ++
Sbjct: 997  RKEKN 1001



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 1/60 (1%)

Query: 78  GRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHR-RSRSPSQRRTRSRSSSWGRNRRRSDS 136
           G +   Q  + +    GQ + +ER     S  R  SRSPS+ RT+S+SSS+GR  R S S
Sbjct: 904 GEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYS 963


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.126    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,215,413
Number of Sequences: 37866
Number of extensions: 454541
Number of successful extensions: 8385
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 354
Number of HSP's successfully gapped in prelim test: 390
Number of HSP's that attempted gapping in prelim test: 2986
Number of HSP's gapped (non-prelim): 2515
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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