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Search of human proteins with 148612882
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148612882 cat eye syndrome chromosome region, candidate 2
[Homo sapiens]
(1484 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 3111 0.0
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 95 6e-19
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 94 1e-18
gi|38788260 bromodomain PHD finger transcription factor isoform ... 89 4e-17
gi|38788274 bromodomain PHD finger transcription factor isoform ... 89 4e-17
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 84 8e-16
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 84 8e-16
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 81 7e-15
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 79 4e-14
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 79 4e-14
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 78 7e-14
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 76 3e-13
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 75 4e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 74 1e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 74 1e-12
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 74 1e-12
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 74 1e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 73 2e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 73 2e-12
gi|164419758 bromodomain containing 2 [Homo sapiens] 72 4e-12
gi|4826806 bromodomain containing 2 [Homo sapiens] 72 4e-12
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 71 7e-12
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 71 9e-12
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 71 9e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 69 3e-11
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 69 4e-11
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 69 4e-11
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 69 4e-11
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 68 8e-11
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 66 3e-10
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 3111 bits (8066), Expect = 0.0
Identities = 1484/1484 (100%), Positives = 1484/1484 (100%)
Query: 1 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI 60
MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
Sbjct: 1 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI 60
Query: 61 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL 120
ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
Sbjct: 61 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL 120
Query: 121 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL 180
CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
Sbjct: 121 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL 180
Query: 181 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ 240
SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
Sbjct: 181 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ 240
Query: 241 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE 300
GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
Sbjct: 241 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE 300
Query: 301 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE 360
LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
Sbjct: 301 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE 360
Query: 361 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP 420
LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP
Sbjct: 361 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP 420
Query: 421 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD 480
NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
Sbjct: 421 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD 480
Query: 481 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP 540
ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
Sbjct: 481 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP 540
Query: 541 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT 600
GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
Sbjct: 541 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT 600
Query: 601 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR 660
RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
Sbjct: 601 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR 660
Query: 661 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS 720
GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
Sbjct: 661 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS 720
Query: 721 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY 780
NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
Sbjct: 721 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY 780
Query: 781 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP 840
RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
Sbjct: 781 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP 840
Query: 841 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM 900
NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
Sbjct: 841 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM 900
Query: 901 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA 960
DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
Sbjct: 901 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA 960
Query: 961 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET 1020
PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
Sbjct: 961 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET 1020
Query: 1021 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE 1080
VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
Sbjct: 1021 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE 1080
Query: 1081 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY 1140
ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
Sbjct: 1081 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY 1140
Query: 1141 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ 1200
MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
Sbjct: 1141 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ 1200
Query: 1201 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK 1260
GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
Sbjct: 1201 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK 1260
Query: 1261 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD 1320
NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
Sbjct: 1261 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD 1320
Query: 1321 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP 1380
NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
Sbjct: 1321 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP 1380
Query: 1381 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE 1440
RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
Sbjct: 1381 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE 1440
Query: 1441 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS 1484
MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
Sbjct: 1441 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS 1484
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 94.7 bits (234), Expect = 6e-19
Identities = 40/106 (37%), Positives = 71/106 (66%)
Query: 427 EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEK 486
++K K+L + D +T + +L +K+H +WPF+EPV +S AP+YY++I+ P+D+ +M +
Sbjct: 721 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE 780
Query: 487 KLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFH 532
+L Y T++ FV D++ + NCR+YN SEY + + LE+ F+
Sbjct: 781 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFY 826
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 94.0 bits (232), Expect = 1e-18
Identities = 39/105 (37%), Positives = 71/105 (67%)
Query: 427 EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEK 486
++K+K+ + D ++ + +L VK+H+ +WPF+EPV + AP YY++I+ PMD+ +M +
Sbjct: 716 KEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSE 775
Query: 487 KLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCF 531
+L Y +K+ F+ D++ +F NC++YN SEY K ++ LE+ F
Sbjct: 776 RLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFF 820
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 88.6 bits (218), Expect = 4e-17
Identities = 67/220 (30%), Positives = 102/220 (46%), Gaps = 30/220 (13%)
Query: 320 TPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK--------RELEEKVKAVEGM 371
TP L QKRK EEE+ + +KK KE +K + ++ K G
Sbjct: 2684 TPTLPAAS-QKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGC 2742
Query: 372 CSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTK 431
+ + G C+ +L EL E ++ P E+ T
Sbjct: 2743 DRCQNWYHGRCVG-------------------ILQSEAELIDE--YVCPQCQSTEDAMTV 2781
Query: 432 DLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGG 491
+ D+ + +VL ++AHK +WPFLEPVD + AP+YY +IK PMD+++ME+++
Sbjct: 2782 LTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRR 2841
Query: 492 LYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCF 531
Y EFV DM +F NCR YN S + + ++ LE F
Sbjct: 2842 YYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2881
Score = 32.3 bits (72), Expect = 3.5
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 5/102 (4%)
Query: 796 GNHGATNQGPLGPD-EKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGV 854
G G + P P E+ P P P T G + R +W +
Sbjct: 3 GRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEV---A 59
Query: 855 PSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGG 896
P + P S+ R PPP PAP S AP + RG GG
Sbjct: 60 PKTRLSSPRGGSSSRRKPPPPPPAPPST-SAPGRGGRGGGGG 100
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 88.6 bits (218), Expect = 4e-17
Identities = 67/220 (30%), Positives = 102/220 (46%), Gaps = 30/220 (13%)
Query: 320 TPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK--------RELEEKVKAVEGM 371
TP L QKRK EEE+ + +KK KE +K + ++ K G
Sbjct: 2701 TPTLPAAS-QKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGC 2759
Query: 372 CSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTK 431
+ + G C+ +L EL E ++ P E+ T
Sbjct: 2760 DRCQNWYHGRCVG-------------------ILQSEAELIDE--YVCPQCQSTEDAMTV 2798
Query: 432 DLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGG 491
+ D+ + +VL ++AHK +WPFLEPVD + AP+YY +IK PMD+++ME+++
Sbjct: 2799 LTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRR 2858
Query: 492 LYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCF 531
Y EFV DM +F NCR YN S + + ++ LE F
Sbjct: 2859 YYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2898
Score = 32.3 bits (72), Expect = 3.5
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 5/102 (4%)
Query: 796 GNHGATNQGPLGPD-EKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGV 854
G G + P P E+ P P P T G + R +W +
Sbjct: 3 GRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEV---A 59
Query: 855 PSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGG 896
P + P S+ R PPP PAP S AP + RG GG
Sbjct: 60 PKTRLSSPRGGSSSRRKPPPPPPAPPST-SAPGRGGRGGGGG 100
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 84.3 bits (207), Expect = 8e-16
Identities = 90/377 (23%), Positives = 143/377 (37%), Gaps = 94/377 (24%)
Query: 412 PPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVD--ESYAP 469
PPE S+ PN P R+ + + L + VL + H+ +WPF +PVD + P
Sbjct: 47 PPETSN--PNKPKRQTNQLQYLLRV---------VLKTLWKHQFAWPFQQPVDAVKLNLP 95
Query: 470 NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLER 529
+YY+IIK PMD+ +++K+L Y +E + D TMF NC YN + M++ LE+
Sbjct: 96 DYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEK 155
Query: 530 CFHRAMMKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQP 589
F + + P E + E I + + R + R G +
Sbjct: 156 LFLQ-KINELPTE----ETEIMIVQAKGRGRGRKETGTA--------------------- 189
Query: 590 MENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPS---QAPFLN 646
+ G ++P T +A + Q+ PP + HP TP Q P +
Sbjct: 190 -KPGVSTVPNTTQASTPPQTQTPQPNPPPVQ-------ATPHPFP-AVTPDLIVQTPVMT 240
Query: 647 QMRPAVPGTFGPLRGSDPATLYGSSGVPEPHP-----GEPVQQRQPFTMQPPVGINSLRG 701
+ P PL+ P P+P P +PVQ P P + + +G
Sbjct: 241 VVPPQ------PLQTPPPVP-------PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG 287
Query: 702 -PRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGG 760
R + ++ P P + +LGQ R
Sbjct: 288 VKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQ----------------------RRESS 325
Query: 761 APARPP--DFPESSEIP 775
P +PP D P+S + P
Sbjct: 326 RPVKPPKKDVPDSQQHP 342
Score = 60.1 bits (144), Expect = 2e-08
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 409 KELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYA 468
K++P H P + ++ K + + K + K +WPF +PVD
Sbjct: 333 KDVPDSQQHPAPEKSSKVSEQLKCC-------SGILKEMFAKKHAAYAWPFYKPVDVEAL 385
Query: 469 P--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526
+Y IIK PMD+S+++ KL Y +EF D++ MF NC KYN E M+
Sbjct: 386 GLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK 445
Query: 527 LERCFHRAMMK 537
L+ F K
Sbjct: 446 LQDVFEMRFAK 456
Score = 38.5 bits (88), Expect = 0.049
Identities = 43/186 (23%), Positives = 65/186 (34%), Gaps = 21/186 (11%)
Query: 854 VPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSS 913
VP++ P ++ + PPPV A F A D ++ +P M +
Sbjct: 196 VPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTP--------DLIVQTPVMTVVPPQPL 247
Query: 914 RVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQ 973
+ PP P QP P P P P +HP + + P+P G + D
Sbjct: 248 QTPPPVPP----QPQPPPAPAPQPVQSHP-PIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
Query: 974 AEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESA 1033
P L PP T++ + P P + D P ++ PE S SE
Sbjct: 303 IHEPPSL---PPEPKTTKLGQRRESSRPVKPPKKDV-----PDSQQHPAPEKSSKVSEQL 354
Query: 1034 DNCKAM 1039
C +
Sbjct: 355 KCCSGI 360
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 84.3 bits (207), Expect = 8e-16
Identities = 90/377 (23%), Positives = 143/377 (37%), Gaps = 94/377 (24%)
Query: 412 PPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVD--ESYAP 469
PPE S+ PN P R+ + + L + VL + H+ +WPF +PVD + P
Sbjct: 47 PPETSN--PNKPKRQTNQLQYLLRV---------VLKTLWKHQFAWPFQQPVDAVKLNLP 95
Query: 470 NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLER 529
+YY+IIK PMD+ +++K+L Y +E + D TMF NC YN + M++ LE+
Sbjct: 96 DYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEK 155
Query: 530 CFHRAMMKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQP 589
F + + P E + E I + + R + R G +
Sbjct: 156 LFLQ-KINELPTE----ETEIMIVQAKGRGRGRKETGTA--------------------- 189
Query: 590 MENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPS---QAPFLN 646
+ G ++P T +A + Q+ PP + HP TP Q P +
Sbjct: 190 -KPGVSTVPNTTQASTPPQTQTPQPNPPPVQ-------ATPHPFP-AVTPDLIVQTPVMT 240
Query: 647 QMRPAVPGTFGPLRGSDPATLYGSSGVPEPHP-----GEPVQQRQPFTMQPPVGINSLRG 701
+ P PL+ P P+P P +PVQ P P + + +G
Sbjct: 241 VVPPQ------PLQTPPPVP-------PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG 287
Query: 702 -PRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGG 760
R + ++ P P + +LGQ R
Sbjct: 288 VKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQ----------------------RRESS 325
Query: 761 APARPP--DFPESSEIP 775
P +PP D P+S + P
Sbjct: 326 RPVKPPKKDVPDSQQHP 342
Score = 68.9 bits (167), Expect = 3e-11
Identities = 134/643 (20%), Positives = 224/643 (34%), Gaps = 116/643 (18%)
Query: 409 KELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYA 468
K++P H P + ++ K + + K + K +WPF +PVD
Sbjct: 333 KDVPDSQQHPAPEKSSKVSEQLKCC-------SGILKEMFAKKHAAYAWPFYKPVDVEAL 385
Query: 469 P--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526
+Y IIK PMD+S+++ KL Y +EF D++ MF NC KYN E M+
Sbjct: 386 GLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK 445
Query: 527 LERCFHR--AMMKHFPGE-------------------------DGDTDEEFWIREDEKRE 559
L+ F A M P E D+ + D+ E
Sbjct: 446 LQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEE 505
Query: 560 KRRSRAGR-----SGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSS 614
+R R P+ + K++ + K +R +++ S +
Sbjct: 506 ERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565
Query: 615 TQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVP 674
+PP + N S+ +++ PA P++ P T Y S
Sbjct: 566 KEPPPKKTKKNNSSNSN-------------VSKKEPA------PMKSKPPPT-YESEEED 605
Query: 675 EPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQI 734
+ P ++R Q + IN L G +LG + H+ + SL+
Sbjct: 606 KCKPMSYEEKR-----QLSLDINKLPGEKLGR---------VVHI--IQSREPSLKNSNP 649
Query: 735 SGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVW 794
D P+ + R P + I S + + S+
Sbjct: 650 DEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSES 709
Query: 795 NGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGV 854
+ + ++ + P K PG + + H ++ + P P +P
Sbjct: 710 SSSDSEDSETEMAPKSKKKGHPG--REQKKHHHHHHQQMQQAPAP----------VPQQP 757
Query: 855 PSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQ-QLSS 913
P PP + QPPP P P S+ P QA ++ + ++ ++ QL
Sbjct: 758 PPPPQQPPPPPPPQQQQQPPPPPPPPSM---PQQAAPAMKSSPPPFIATQVPVLEPQLPG 814
Query: 914 RVCPP------GVPYHPHQPAHPRLPGPFPQVAHPMSVTVSA--PKPALGNPGRAPENSE 965
V P + + P P LP P P+ + P + A PAL N+
Sbjct: 815 SVFDPIGHFTQPILHLPQPELPPHLPQP-PEHSTPPHLNQHAVVSPPAL-------HNAL 866
Query: 966 AQEPE--NDQAEPLPGLEEKPPGVGTSEGVYLTQLP-HPTPPL 1005
Q+P +++A LP +PP V + LTQ P P PP+
Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPA----LTQTPLLPQPPM 905
Score = 44.3 bits (103), Expect = 9e-04
Identities = 74/303 (24%), Positives = 101/303 (33%), Gaps = 55/303 (18%)
Query: 746 PAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGP 805
P Q P PP+ P PP P + M S V + P
Sbjct: 760 PPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDP 819
Query: 806 LG-----------PDEKPHLGPGPSHQPRTLGHVMDSRVMRPPV-------PPNQWTEQS 847
+G P+ PHL P H T H+ V+ PP P++ + ++
Sbjct: 820 IGHFTQPILHLPQPELPPHLPQPPEHS--TPPHLNQHAVVSPPALHNALPQQPSRPSNRA 877
Query: 848 GFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIA 907
LP P RPP S Q P +P P P Q L D +P + +
Sbjct: 878 AALP---PKPA--RPPAVSPA-LTQTPLLPQPP--MAQPPQVLLE----DEEPPAPPLTS 925
Query: 908 MQ-----QLSSRVCPPGVPYHPH-----QPAHPRLPGPFPQVAHPMSVTVSAPKPALGNP 957
MQ Q +V PP P P QP P P P P V + P P P
Sbjct: 926 MQMQLYLQQLQKVQPP-TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP--QP 982
Query: 958 GRAPENSEAQEPENDQAEPL---PGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSS 1014
P+ P +P+ +++ PP G Q PHP P Q + +
Sbjct: 983 QPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQG-------QQPPHPPPGQQPPPPQPAK 1035
Query: 1015 PQE 1017
PQ+
Sbjct: 1036 PQQ 1038
Score = 42.4 bits (98), Expect = 0.003
Identities = 75/290 (25%), Positives = 91/290 (31%), Gaps = 67/290 (23%)
Query: 1169 KSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACPQS 1228
++PA PQ PP Q P PPQ + PPP PS + P
Sbjct: 748 QAPAPVPQQPPPPPQQPPPPP--------PPQQQQQPPPPPPPPSMPQQAAPAMKSSPPP 799
Query: 1229 FSDWQRP-LHPQ--GS-----------------PSGPPASQPPPPRSLFSDKNAMASLQG 1268
F Q P L PQ GS P PP PP S N A +
Sbjct: 800 FIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP 859
Query: 1269 CETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPE----SPKEFLDLDNHNA 1324
NA P+R AA +P P L ++ P+ P + L D
Sbjct: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP 919
Query: 1325 A---TKRQSSLSASEYLYGTPP-PLSSGMGFGSSAFPP----------HSVMLQTGPPYT 1370
A T Q L + PP PL + S PP + Q PP
Sbjct: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP 979
Query: 1371 PQ-------------RPASHFQPRAYSS-------PVAALPPHHPGATQP 1400
PQ RP H QP +S+ P PPH P QP
Sbjct: 980 PQPQPPPQQQHQPPPRPV-HLQPMQFSTHIQQPPPPQGQQPPHPPPGQQP 1028
Score = 42.0 bits (97), Expect = 0.004
Identities = 42/152 (27%), Positives = 55/152 (36%), Gaps = 20/152 (13%)
Query: 1119 ATPPSTDPGLTGGTVSQFPPLYMPG-------------LEYPNSAAHYHISPGLQGVGPV 1165
A PP+ P LT + PP+ P L + +Q P+
Sbjct: 885 ARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPL 944
Query: 1166 MGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYAC 1225
+ S P PP HP + +PP PPPQ + R P +
Sbjct: 945 LPSVKVQSQP---PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR-PVHLQ 1000
Query: 1226 PQSFSDW-QRPLHPQGS--PSGPPASQPPPPR 1254
P FS Q+P PQG P PP QPPPP+
Sbjct: 1001 PMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ 1032
Score = 41.6 bits (96), Expect = 0.006
Identities = 107/580 (18%), Positives = 180/580 (31%), Gaps = 28/580 (4%)
Query: 904 EMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPEN 963
E++AM + V P +P P + P V P V + + +
Sbjct: 438 EVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSD 497
Query: 964 SEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGP 1023
S + E ++A+ L L+E+ V E + P P + + ++ +E+
Sbjct: 498 SSTDDSEEERAQRLAELQEQLKAV--HEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKE 555
Query: 1024 ELKSSSSESADNC--KAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEA 1081
E++ + A K K N S+ S PA + E+ +
Sbjct: 556 EVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMK--------SKPPPTYESEEEDKC 607
Query: 1082 SPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYM 1141
P E K S KL G L + + +++P P +
Sbjct: 608 KPMSYEEKRQLSLDINKL---PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTL 664
Query: 1142 PGLE-YPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ 1200
LE Y S P + V + G +S+ S P+
Sbjct: 665 RELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPK 724
Query: 1201 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQ---PPPPRSLF 1257
+ + Q +HH+ P P Q P PP Q PPPP
Sbjct: 725 SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPS 784
Query: 1258 SDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFL 1317
+ A +++ A T++ + ++P +P + + +PE P
Sbjct: 785 MPQQAAPAMKSSPPPFIA----TQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP 840
Query: 1318 DLDNHNAATK-RQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPAS 1376
H+ Q ++ + L+ P S ++A PP P Q P
Sbjct: 841 QPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL 900
Query: 1377 HFQPRAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRG 1436
QP P L P A P S + +Y Q + + ++ + +S
Sbjct: 901 P-QPPMAQPPQVLLEDEEPPA--PPLTSMQMQLYLQQLQKV-QPPTPLLPSVKVQSQPPP 956
Query: 1437 PFQEMYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKP 1476
P PS Q Q P P Q+ PP +P
Sbjct: 957 PLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP 996
Score = 39.3 bits (90), Expect = 0.029
Identities = 134/692 (19%), Positives = 222/692 (32%), Gaps = 127/692 (18%)
Query: 318 EETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVV 377
E+ L++ ++ K K++E++++ +KK++ K +RK E+EE K+
Sbjct: 523 EQLAALSQPQQNKPKKKEKDKK-----EKKKE----KHKRKEEVEENKKSK--------- 564
Query: 378 WRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDL---- 433
+ P + K+ KE P S P EE K K +
Sbjct: 565 ------AKEPPPKKTKKNNSSNSNV----SKKEPAPMKSKPPPTYESEEEDKCKPMSYEE 614
Query: 434 ---FELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNG 490
LD + K+ VV + P L+ + ++ +K P + +E+ +
Sbjct: 615 KRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK-PSTLRELERYVTS 673
Query: 491 GLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFPGEDGDTDEEF 550
L ++ + + + + SSE S E +D E
Sbjct: 674 CLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSS-----------------ESSSSDSED 716
Query: 551 WIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQ 610
E + K++ GR H +Q P + PP ++ P Q
Sbjct: 717 SETEMAPKSKKKGHPGREQKKH-----HHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQ 771
Query: 611 SSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGT-FGPLRGSDPATLYG 669
PP S + + + P A + + P +PG+ F P+ L+
Sbjct: 772 QQQQPPPPPPP-PSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHL 830
Query: 670 SSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSL 729
PH +P + P P + +++ P L N P
Sbjct: 831 PQPELPPHLPQPPEHSTP----PHLNQHAVVSPPA--------------LHNALPQ---- 868
Query: 730 QLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAP-------ARPPDFPESSEIPPSHMYRS 782
Q S PS + P +P + P P A+PP E PP+ S
Sbjct: 869 ---QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTS 925
Query: 783 YK---YLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVP 839
+ YL ++ PL P K P P P V +PP P
Sbjct: 926 MQMQLYLQQLQKV--------QPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPP 977
Query: 840 PNQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSM 899
P + H P P + + H QPPP P G Q
Sbjct: 978 PPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQ-----PPHPPPGQQPPPPQ 1032
Query: 900 MDSPEMIAMQQLSSRVCPPGVPYH---PHQPAHPR-LPGPF----PQVAHPMSVTVSAPK 951
P+ + S R +H P+ H R P P PQ++ S+T +P
Sbjct: 1033 PAKPQQVIQHHHSPR-------HHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPP 1085
Query: 952 PALGNPGRAPENSEAQEPENDQAEPLPGLEEK 983
P+ E + Q +PL ++E+
Sbjct: 1086 ----QQNVQPKKQELRAASVVQPQPLVVVKEE 1113
Score = 38.5 bits (88), Expect = 0.049
Identities = 43/186 (23%), Positives = 65/186 (34%), Gaps = 21/186 (11%)
Query: 854 VPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSS 913
VP++ P ++ + PPPV A F A D ++ +P M +
Sbjct: 196 VPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTP--------DLIVQTPVMTVVPPQPL 247
Query: 914 RVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQ 973
+ PP P QP P P P P +HP + + P+P G + D
Sbjct: 248 QTPPPVPP----QPQPPPAPAPQPVQSHP-PIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
Query: 974 AEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESA 1033
P L PP T++ + P P + D P ++ PE S SE
Sbjct: 303 IHEPPSL---PPEPKTTKLGQRRESSRPVKPPKKDV-----PDSQQHPAPEKSSKVSEQL 354
Query: 1034 DNCKAM 1039
C +
Sbjct: 355 KCCSGI 360
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 81.3 bits (199), Expect = 7e-15
Identities = 54/194 (27%), Positives = 87/194 (44%), Gaps = 5/194 (2%)
Query: 348 EQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQ 407
E ++ +EE + E EE + R RG S P R+ RR ++ + +Q
Sbjct: 1258 ESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKH-SVIPPAARSGRRPGKKPHSTRRSQ 1316
Query: 408 GKELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESY 467
K P + + +D + + EL ++K++ ++ SWPF EPV
Sbjct: 1317 PKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVK----YRFSWPFREPVTRDE 1372
Query: 468 APNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNL 527
A +YY +I PMD +++ K + G Y + +EF+ DMK +F N YN S
Sbjct: 1373 AEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKT 1432
Query: 528 ERCFHRAMMKHFPG 541
E+C + KH PG
Sbjct: 1433 EQCLVALLHKHLPG 1446
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 78.6 bits (192), Expect = 4e-14
Identities = 39/119 (32%), Positives = 67/119 (56%), Gaps = 6/119 (5%)
Query: 425 REEKKTKDLFELDDDFTAMYKVLDVVKAHK-----DSWPFLEPVDESYAPNYYQIIKAPM 479
R EK L + DDD A +LD + K DSWPF PV++ + P+YY++I PM
Sbjct: 1490 RLEKAINPLLD-DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPM 1548
Query: 480 DISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKH 538
D+ ++ K ++ Y ++E F++D+ + N KYNG S+YTK + + ++ + ++
Sbjct: 1549 DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEY 1607
Score = 55.5 bits (132), Expect = 4e-07
Identities = 46/189 (24%), Positives = 91/189 (48%), Gaps = 11/189 (5%)
Query: 342 LAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREER 401
+A+ ++++E++ K + EE +K VEG V G L S R K L+ +
Sbjct: 1293 VAMTEEQEEELEKTVIHNDNEELIK-VEGTKIVL----GKQLIESADEVRRKSLVLKFPK 1347
Query: 402 AWLLAQGKELPPELSHLDP-NSPMRE--EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWP 458
L + K H D N P + ++T + L + + +++ ++ +++P
Sbjct: 1348 QQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLS---SILESIINDMRDLPNTYP 1404
Query: 459 FLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESS 518
F PV+ +YY+II PMD+ ++ + + LY ++EEF ++ + +N YNG
Sbjct: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464
Query: 519 EYTKMSDNL 527
T++S ++
Sbjct: 1465 SLTQISQSM 1473
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 78.6 bits (192), Expect = 4e-14
Identities = 39/119 (32%), Positives = 67/119 (56%), Gaps = 6/119 (5%)
Query: 425 REEKKTKDLFELDDDFTAMYKVLDVVKAHK-----DSWPFLEPVDESYAPNYYQIIKAPM 479
R EK L + DDD A +LD + K DSWPF PV++ + P+YY++I PM
Sbjct: 1511 RLEKAINPLLD-DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPM 1569
Query: 480 DISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKH 538
D+ ++ K ++ Y ++E F++D+ + N KYNG S+YTK + + ++ + ++
Sbjct: 1570 DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEY 1628
Score = 55.5 bits (132), Expect = 4e-07
Identities = 46/189 (24%), Positives = 91/189 (48%), Gaps = 11/189 (5%)
Query: 342 LAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREER 401
+A+ ++++E++ K + EE +K VEG V G L S R K L+ +
Sbjct: 1314 VAMTEEQEEELEKTVIHNDNEELIK-VEGTKIVL----GKQLIESADEVRRKSLVLKFPK 1368
Query: 402 AWLLAQGKELPPELSHLDP-NSPMRE--EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWP 458
L + K H D N P + ++T + L + + +++ ++ +++P
Sbjct: 1369 QQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLS---SILESIINDMRDLPNTYP 1425
Query: 459 FLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESS 518
F PV+ +YY+II PMD+ ++ + + LY ++EEF ++ + +N YNG
Sbjct: 1426 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1485
Query: 519 EYTKMSDNL 527
T++S ++
Sbjct: 1486 SLTQISQSM 1494
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 77.8 bits (190), Expect = 7e-14
Identities = 45/154 (29%), Positives = 76/154 (49%), Gaps = 19/154 (12%)
Query: 384 STSRPVDRA----KRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFELDDD 439
STS + R K+RK+ E + L++ + S P R++ K D
Sbjct: 2021 STSSSLKRGNKDLKKRKMEENTSINLSKQE------SFTSVKKPKRDDSK---------D 2065
Query: 440 FTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEF 499
+L ++ H+D+WPFL PV+ P Y ++IK PMD S++ +KL+ G Y E F
Sbjct: 2066 LALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETF 2125
Query: 500 VNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHR 533
D++ +F NC +N + S+ + N+ + F +
Sbjct: 2126 ALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEK 2159
Score = 33.5 bits (75), Expect = 1.6
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
Query: 255 QVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRP----QRTKAELHPRWMSDHL 310
+V + + R + Q L ED +P I M ++G+ P QR + E R
Sbjct: 810 RVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRP 869
Query: 311 ----SIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE----LE 362
+ + + + +L +++ Q+ + + ++L +QK+EQ ++ KE +K++ E
Sbjct: 870 PNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAE 929
Query: 363 EKVKAVE 369
EK K E
Sbjct: 930 EKRKQKE 936
Score = 33.5 bits (75), Expect = 1.6
Identities = 59/251 (23%), Positives = 102/251 (40%), Gaps = 42/251 (16%)
Query: 200 RRGRPPK--RKKLQEEILLSEKQ--------------EENSLASEPQTRHGSQGPGQGTW 243
RRGRPP R++ +EE + ++ + L + Q + ++ Q
Sbjct: 844 RRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKL 903
Query: 244 WLLCQTEEEWRQVTESFRERTSL------RERQLYKLLSEDFLPEICNMIAQKGKRPQRT 297
Q +E+ R E+ +++ + ++++ K++ + +K KR Q+
Sbjct: 904 LRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQ----------EKIKRIQQI 953
Query: 298 KAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEER 357
+ E R L K K+EE +E +KR +E+E R+ AV K QE+ ER
Sbjct: 954 RMEKELR-AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRR-QQAVLLKHQER----ER 1007
Query: 358 KRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKEL--PPEL 415
+R+ +KA+E R R R + + E+R L KEL P E
Sbjct: 1008 RRQHMMLMKAMEARKKAEEKER--LKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNED 1065
Query: 416 SHLDPNSPMRE 426
L P+ E
Sbjct: 1066 MCLADQKPLPE 1076
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 75.9 bits (185), Expect = 3e-13
Identities = 38/119 (31%), Positives = 67/119 (56%), Gaps = 6/119 (5%)
Query: 425 REEKKTKDLFELDDDFTAMYKVLDVVKAHK-----DSWPFLEPVDESYAPNYYQIIKAPM 479
R EK L + DDD A +LD + K DSWPF PV++ + P+YY++I P+
Sbjct: 1509 RLEKAINPLLD-DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPV 1567
Query: 480 DISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKH 538
D+ ++ K ++ Y ++E F++D+ + N KYNG S+YTK + + ++ + ++
Sbjct: 1568 DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEY 1626
Score = 53.1 bits (126), Expect = 2e-06
Identities = 44/189 (23%), Positives = 92/189 (48%), Gaps = 11/189 (5%)
Query: 342 LAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREER 401
+A+ ++++E++ K + EE +K VEG ++V+ + V R K L+ +
Sbjct: 1312 VAMTEEQEEELEKTVIHNDNEELIK-VEG---TKIVFGKQLIENVHEV-RRKSLVLKFPK 1366
Query: 402 AWLLAQGKELPPELSHLDP-NSPMRE--EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWP 458
L + K H D N P + ++T + L + + +++ ++ ++ P
Sbjct: 1367 QQLPPKKKRRVGTTVHCDYLNIPHKSIHRRRTDPMVTLS---SILESIINDMRDLPNTHP 1423
Query: 459 FLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESS 518
F PV+ +YY+II PMD+ ++ + + LY ++EEF ++ + +N YNG
Sbjct: 1424 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKH 1483
Query: 519 EYTKMSDNL 527
T++S ++
Sbjct: 1484 SLTQISQSM 1492
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 75.5 bits (184), Expect = 4e-13
Identities = 42/145 (28%), Positives = 69/145 (47%)
Query: 401 RAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFL 460
R +L +G+E P +++ + D T +L +++H +WPFL
Sbjct: 1760 RRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLTFCEIILMEMESHDAAWPFL 1819
Query: 461 EPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEY 520
EPV+ Y +IIK PMD S+M ++L G Y + EEF D +F NC+ +N + SE
Sbjct: 1820 EPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEV 1879
Query: 521 TKMSDNLERCFHRAMMKHFPGEDGD 545
K + R F + + G+ +
Sbjct: 1880 GKAGHIMRRFFESRWEEFYQGKQAN 1904
Score = 35.4 bits (80), Expect = 0.41
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 15/167 (8%)
Query: 269 RQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQEETPVLTRIE- 327
R L KL +++ L E K K+ R K + + + +++ET L + E
Sbjct: 691 RPLKKLEAQETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEA 750
Query: 328 KQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSR 387
K+K K E+E + K +++ LKE+ KRE +EKVK E + + AC +
Sbjct: 751 KKKSKAEKE--------KGKTKQEKLKEKVKREKKEKVKMKEKEEVTKA--KPACKADK- 799
Query: 388 PVDRAKRRKLRE-ERAWLLAQGKELPPELSHLDPNSPMREEKKTKDL 433
A +R+L E +R ++ + + P E L + P+ + + L
Sbjct: 800 --TLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSRVPGL 844
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 73.9 bits (180), Expect = 1e-12
Identities = 197/916 (21%), Positives = 282/916 (30%), Gaps = 183/916 (19%)
Query: 616 QPPREVGTSNGRGFSHPLHCGGTP----SQAPFLNQMRPAVPGTFGPLRG------SDPA 665
QPP+ + G G PL GTP SQ P + +P PGT P++G +D A
Sbjct: 214 QPPKPIPKQQGPG-RDPLQQDGTPKSISSQQPEKIKSQP--PGTGKPIQGPTQTPQTDHA 270
Query: 666 TLYGSSGVPEPHP-------GEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTH 718
L P GE V+ P +PP+ + P G P +Q
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPI-----QQPTPGKPPAQQ------- 318
Query: 719 LSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFI-----------PPRHGGAPARPPD 767
P Q G P+Q + P QPG + PP PA+PP
Sbjct: 319 -----PGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 768 FPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGH 827
SE P S GP + P +G P+ QP
Sbjct: 374 QQTGSEKPSSE-----------------------QPGPKALAQPPGVGKTPAQQP----- 405
Query: 828 VMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPA 887
P PP T+Q G P + ++ P K+ G P P P + PA
Sbjct: 406 -------GPAKPP---TQQVG-TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI---PA 451
Query: 888 QALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTV 947
Q + G S + QL PP P QP + P P A P S
Sbjct: 452 Q--QAGPGKTSAQQTGPTKPPSQLPGPAKPP-----PQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 948 SAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQT 1007
+ KP PG P Q+P + KPP Q P P P
Sbjct: 505 GSTKPPPQQPG--PAKPSPQQPGS----------TKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 1008 DCTRQSS------PQERETVGPELKSSSSESADN-----CKAMKGKNPWPSDSSYPGPAA 1056
T+ S P + TV P K S+ C + P +++
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF----- 607
Query: 1057 QGCVRDLSTVADRGALSENGVIGEASP--CGSEGKGLGSSGSEKLLCPRGRTLQETMPCT 1114
C +TV + N + E C L C R L +
Sbjct: 608 NTCTECQTTVCSLCGFNPNPHLTEVKEWLC--------------LNCQMKRALGGDLAPV 653
Query: 1115 GQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASH 1174
+ T P T VS+ P ++A +S + P K P H
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 1175 PQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACP-----QSF 1229
P P + + PP+ P + P P S
Sbjct: 714 GS---PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
Query: 1230 SDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKV 1289
S +P P + PP S K + + E ++ + A +K+
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830
Query: 1290 PNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGM 1349
+ +PGP E + P KE + A TK A G+P P
Sbjct: 831 IS---HPGPSSESKGQKQVDPVQKKE----EPKKAQTKMSPKPDAKPMPKGSPTPPG--- 880
Query: 1350 GFGSSAFPPHSVMLQTGPPYTPQR-PASHFQPRAYSSPVAAL---PPHHPGATQPNGLSQ 1405
P QT P TPQ+ P Q R +S + ++ P P Q +
Sbjct: 881 --------PRPTAGQTVP--TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE---TV 927
Query: 1406 EGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQASFPKTPTAA 1465
G ++ G G + + +G GP + + M+ P SQ + P +
Sbjct: 928 TGKLF-----GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS 982
Query: 1466 TSQEEVPPHKPPTLPL 1481
T Q PP ++P+
Sbjct: 983 TGQ--APPAPAKSIPV 996
Score = 46.2 bits (108), Expect = 2e-04
Identities = 123/523 (23%), Positives = 178/523 (34%), Gaps = 89/523 (17%)
Query: 589 PMENGGKSLPPTRR-APSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQ 647
P++ G + PP + P+ Q + S +P E + + P G TP+Q P +
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE--QPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 648 MRPAVPGTFGPLRGS----DPATLYGSSGVP--EPHPGE-PVQQRQPFTMQ-----PPVG 695
GT PL PA G + P +P PG+ P QQ P P
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 696 INSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFI- 754
+ L GP P++ PG + P Q GS P+Q QPG
Sbjct: 470 PSQLPGPAKPPPQQ----------------PGPAK----PPPQQPGSAKPPSQ-QPGSTK 508
Query: 755 PPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHS----AVWNGNHGATNQGPLGPDE 810
PP PA+P S PPS S K + S + + G P +
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 811 KPHLGPG---PSHQ--PRTLGHVMDSRVMRPPVPP----NQWTE-------QSGF--LPH 852
P + P P Q P+T+ + ++ + VP N TE GF PH
Sbjct: 569 PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPH 628
Query: 853 GVPSSGYMRPPC---KSAGHRLQPPPVPAPSSLFGAPAQALRGV--QGGDSMMDSPEM-I 906
++ C ++ G L P P L AP V SP+
Sbjct: 629 LTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA 688
Query: 907 AMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEA 966
A +Q S+ P P P P L G A S KPA P +
Sbjct: 689 APKQDLSKAPEPKKP--PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Query: 967 QEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLP----------HPTPPLQTDCTR--QSS 1014
+D+ + ++ V +S +P TPPL+TD + QS
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 1015 PQERETVGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQ 1057
P E V P + A + K + S+PGP+++
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKII----------SHPGPSSE 839
Score = 37.7 bits (86), Expect = 0.083
Identities = 61/284 (21%), Positives = 94/284 (33%), Gaps = 56/284 (19%)
Query: 1239 QGSPSG---PPASQPPP---PRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPND 1292
QG P G PP Q PP P+ ++ + +++++ + P
Sbjct: 200 QGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ 259
Query: 1293 GQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFG 1352
G P+ + ++R S + D + + S S S+ PP+
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK------PPIQQPTPGK 313
Query: 1353 SSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQP------------ 1400
A P Q GP P +P+ +P A P PG T+P
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 1401 -------NGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHP-V 1452
Q GP Q G+G A +Q G + P Q++ P + P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPA---QQPGP---AKPPTQQVGTPKPLAQQPGL 427
Query: 1453 QSQASFP---KTPT---------------AATSQEEVPPHKPPT 1478
QS A P KTP TS ++ P KPP+
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Score = 33.1 bits (74), Expect = 2.0
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 15/120 (12%)
Query: 316 KQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVR 375
K PV T QK + + + K+QEQ +K E ++ + EKVK M +
Sbjct: 1133 KASPMPVPTESSSQKTAVPPQVKLV------KKQEQEVKTEAEKVILEKVKETLSMEKIP 1186
Query: 376 VVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFE 435
+ ++T + + + KL +++A L + K LP E + +R E+K K L E
Sbjct: 1187 PM-----VTTDQ---KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK-KPLLE 1237
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 73.9 bits (180), Expect = 1e-12
Identities = 197/916 (21%), Positives = 282/916 (30%), Gaps = 183/916 (19%)
Query: 616 QPPREVGTSNGRGFSHPLHCGGTP----SQAPFLNQMRPAVPGTFGPLRG------SDPA 665
QPP+ + G G PL GTP SQ P + +P PGT P++G +D A
Sbjct: 214 QPPKPIPKQQGPG-RDPLQQDGTPKSISSQQPEKIKSQP--PGTGKPIQGPTQTPQTDHA 270
Query: 666 TLYGSSGVPEPHP-------GEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTH 718
L P GE V+ P +PP+ + P G P +Q
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPI-----QQPTPGKPPAQQ------- 318
Query: 719 LSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFI-----------PPRHGGAPARPPD 767
P Q G P+Q + P QPG + PP PA+PP
Sbjct: 319 -----PGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 768 FPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGH 827
SE P S GP + P +G P+ QP
Sbjct: 374 QQTGSEKPSSE-----------------------QPGPKALAQPPGVGKTPAQQP----- 405
Query: 828 VMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPA 887
P PP T+Q G P + ++ P K+ G P P P + PA
Sbjct: 406 -------GPAKPP---TQQVG-TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI---PA 451
Query: 888 QALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTV 947
Q + G S + QL PP P QP + P P A P S
Sbjct: 452 Q--QAGPGKTSAQQTGPTKPPSQLPGPAKPP-----PQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 948 SAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQT 1007
+ KP PG P Q+P + KPP Q P P P
Sbjct: 505 GSTKPPPQQPG--PAKPSPQQPGS----------TKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 1008 DCTRQSS------PQERETVGPELKSSSSESADN-----CKAMKGKNPWPSDSSYPGPAA 1056
T+ S P + TV P K S+ C + P +++
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF----- 607
Query: 1057 QGCVRDLSTVADRGALSENGVIGEASP--CGSEGKGLGSSGSEKLLCPRGRTLQETMPCT 1114
C +TV + N + E C L C R L +
Sbjct: 608 NTCTECQTTVCSLCGFNPNPHLTEVKEWLC--------------LNCQMKRALGGDLAPV 653
Query: 1115 GQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASH 1174
+ T P T VS+ P ++A +S + P K P H
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 1175 PQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACP-----QSF 1229
P P + + PP+ P + P P S
Sbjct: 714 GS---PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
Query: 1230 SDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKV 1289
S +P P + PP S K + + E ++ + A +K+
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830
Query: 1290 PNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGM 1349
+ +PGP E + P KE + A TK A G+P P
Sbjct: 831 IS---HPGPSSESKGQKQVDPVQKKE----EPKKAQTKMSPKPDAKPMPKGSPTPPG--- 880
Query: 1350 GFGSSAFPPHSVMLQTGPPYTPQR-PASHFQPRAYSSPVAAL---PPHHPGATQPNGLSQ 1405
P QT P TPQ+ P Q R +S + ++ P P Q +
Sbjct: 881 --------PRPTAGQTVP--TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE---TV 927
Query: 1406 EGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQASFPKTPTAA 1465
G ++ G G + + +G GP + + M+ P SQ + P +
Sbjct: 928 TGKLF-----GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS 982
Query: 1466 TSQEEVPPHKPPTLPL 1481
T Q PP ++P+
Sbjct: 983 TGQ--APPAPAKSIPV 996
Score = 46.2 bits (108), Expect = 2e-04
Identities = 123/523 (23%), Positives = 178/523 (34%), Gaps = 89/523 (17%)
Query: 589 PMENGGKSLPPTRR-APSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQ 647
P++ G + PP + P+ Q + S +P E + + P G TP+Q P +
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE--QPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 648 MRPAVPGTFGPLRGS----DPATLYGSSGVP--EPHPGE-PVQQRQPFTMQ-----PPVG 695
GT PL PA G + P +P PG+ P QQ P P
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 696 INSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFI- 754
+ L GP P++ PG + P Q GS P+Q QPG
Sbjct: 470 PSQLPGPAKPPPQQ----------------PGPAK----PPPQQPGSAKPPSQ-QPGSTK 508
Query: 755 PPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHS----AVWNGNHGATNQGPLGPDE 810
PP PA+P S PPS S K + S + + G P +
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 811 KPHLGPG---PSHQ--PRTLGHVMDSRVMRPPVPP----NQWTE-------QSGF--LPH 852
P + P P Q P+T+ + ++ + VP N TE GF PH
Sbjct: 569 PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPH 628
Query: 853 GVPSSGYMRPPC---KSAGHRLQPPPVPAPSSLFGAPAQALRGV--QGGDSMMDSPEM-I 906
++ C ++ G L P P L AP V SP+
Sbjct: 629 LTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA 688
Query: 907 AMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEA 966
A +Q S+ P P P P L G A S KPA P +
Sbjct: 689 APKQDLSKAPEPKKP--PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Query: 967 QEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLP----------HPTPPLQTDCTR--QSS 1014
+D+ + ++ V +S +P TPPL+TD + QS
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 1015 PQERETVGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQ 1057
P E V P + A + K + S+PGP+++
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKII----------SHPGPSSE 839
Score = 37.7 bits (86), Expect = 0.083
Identities = 61/284 (21%), Positives = 94/284 (33%), Gaps = 56/284 (19%)
Query: 1239 QGSPSG---PPASQPPP---PRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPND 1292
QG P G PP Q PP P+ ++ + +++++ + P
Sbjct: 200 QGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ 259
Query: 1293 GQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFG 1352
G P+ + ++R S + D + + S S S+ PP+
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK------PPIQQPTPGK 313
Query: 1353 SSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQP------------ 1400
A P Q GP P +P+ +P A P PG T+P
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 1401 -------NGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHP-V 1452
Q GP Q G+G A +Q G + P Q++ P + P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPA---QQPGP---AKPPTQQVGTPKPLAQQPGL 427
Query: 1453 QSQASFP---KTPT---------------AATSQEEVPPHKPPT 1478
QS A P KTP TS ++ P KPP+
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Score = 33.1 bits (74), Expect = 2.0
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 15/120 (12%)
Query: 316 KQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVR 375
K PV T QK + + + K+QEQ +K E ++ + EKVK M +
Sbjct: 1133 KASPMPVPTESSSQKTAVPPQVKLV------KKQEQEVKTEAEKVILEKVKETLSMEKIP 1186
Query: 376 VVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFE 435
+ ++T + + + KL +++A L + K LP E + +R E+K K L E
Sbjct: 1187 PM-----VTTDQ---KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK-KPLLE 1237
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 73.6 bits (179), Expect = 1e-12
Identities = 45/125 (36%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Query: 411 LPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVL--DVVKAHKDSWPFLEPVD--ES 466
LP + + N P E TK L + + KV+ D+ K H SWPF PVD +
Sbjct: 3 LPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWK-HSFSWPFQRPVDAVKL 61
Query: 467 YAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526
P+YY IIK PMD+++++K+L Y E + D TMF NC YN + M+
Sbjct: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
Query: 527 LERCF 531
LE+ F
Sbjct: 122 LEKLF 126
Score = 59.7 bits (143), Expect = 2e-08
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 456 SWPFLEPVDESYAP--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKY 513
+WPF PVD + NYY ++K PMD+ ++++K++ Y +F D++ MF NC KY
Sbjct: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
Query: 514 NGESSEYTKMSDNLERCFHRAMMK 537
N E M+ L+ F K
Sbjct: 352 NPPDHEVVTMARMLQDVFETHFSK 375
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 73.6 bits (179), Expect = 1e-12
Identities = 45/125 (36%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Query: 411 LPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVL--DVVKAHKDSWPFLEPVD--ES 466
LP + + N P E TK L + + KV+ D+ K H SWPF PVD +
Sbjct: 3 LPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWK-HSFSWPFQRPVDAVKL 61
Query: 467 YAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526
P+YY IIK PMD+++++K+L Y E + D TMF NC YN + M+
Sbjct: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121
Query: 527 LERCF 531
LE+ F
Sbjct: 122 LEKLF 126
Score = 59.7 bits (143), Expect = 2e-08
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 456 SWPFLEPVDESYAP--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKY 513
+WPF PVD + NYY ++K PMD+ ++++K++ Y +F D++ MF NC KY
Sbjct: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
Query: 514 NGESSEYTKMSDNLERCFHRAMMK 537
N E M+ L+ F K
Sbjct: 352 NPPDHEVVTMARMLQDVFETHFSK 375
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 73.2 bits (178), Expect = 2e-12
Identities = 145/587 (24%), Positives = 188/587 (32%), Gaps = 106/587 (18%)
Query: 579 DPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGF-SHPLHCGG 637
+P ++R++ P GG P +R SS SS + P GT S P G
Sbjct: 219 EPSPAARRR-PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 638 TPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGIN 697
+ P + R GPL S AT P P +Q + P T+
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLAT---------PSPSAALQSQAPPTLP------ 322
Query: 698 SLRGPRLGTPEEKQM-CGGLTHLSNMGPHPGS------LQLGQISGPSQ-DGSMYAPA-Q 748
TP + C T L P P + L + PSQ S+ +P Q
Sbjct: 323 -------ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 375
Query: 749 FQPGFIP-PRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGPLG 807
F+P P PP P + +PP A P
Sbjct: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQ---------------------APPSPPAS 414
Query: 808 PDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSA 867
P P P P H++ + PP PP Q+ F P P P A
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP----VQAPFSPPASPPVSPSATPPSQA 470
Query: 868 GHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVP---YHP 924
L PP+ P S +P + +P +A L PP P P
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMS----PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526
Query: 925 HQPAHPRLPGPFPQVAHPMSVTVSAP-KPALGNPGRAPENSEA---QEPENDQAEPLPGL 980
A P P FP A P S + S P P P +AP A Q P + A P
Sbjct: 527 PLQALPSPPASFPGQA-PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
Query: 981 EEKPPGVGTSEGV-----YLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADN 1035
+PP G V L P P PP S GP+L SS +
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPP-------PSRSPSSTLSGPDLAGHSSSATST 638
Query: 1036 CKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGL---- 1091
+ ++G DS G AA D A A G + G+ G L
Sbjct: 639 PEELRG-----YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 693
Query: 1092 -GSSGSEKLLCPRGRTLQETMPCTGQNAATP------PSTDPGLTGG 1131
GS LC T+ ET G +ATP P PG +GG
Sbjct: 694 ATGPGSADGLC----TIYET---EGPESATPAPGALDPGPSPGTSGG 733
Score = 53.5 bits (127), Expect = 1e-06
Identities = 116/526 (22%), Positives = 166/526 (31%), Gaps = 56/526 (10%)
Query: 746 PAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGP 805
PA PG + PR G+P PP ++ + + + R A G G G
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAA----LRVLGAAGAVGRKPLAERAGGIG----GA 68
Query: 806 LGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCK 865
P+ P GP R+ G + RPP SG P+ P
Sbjct: 69 TIPESAPRAGP-----TRSAGTSSRNPASRPPA--------SGRGERAPPAKNTSPGPVS 115
Query: 866 SAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPH 925
S G R P P G A V G + ++P+ A+ + R P P
Sbjct: 116 SPG-RASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSAGARRDTSGPTPGTPS 173
Query: 926 QPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPP 985
R +V P + P+P P P S + E+ EP P +P
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRP----PTEGPRKSVSSASEHSTTEPSPAARRRPS 229
Query: 986 GVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNCKAMKGKNPW 1045
G + L PL + +S P R T ++ + S K ++ P
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPA--RSGPSARGTP----RAPAHPSQPKPKGLQALRPP 283
Query: 1046 ----PSDSSYP--GPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGSSGSEKL 1099
P + P GP + L+T + AL P L + L
Sbjct: 284 QVTPPRKDAAPALGPLSSS---PLATPSPSAALQSQAP--PTLPATPHSSSLTCQLATPL 338
Query: 1100 -LCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPG 1158
L P + ++ ATPPS G Q ++P A +P
Sbjct: 339 PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 398
Query: 1159 LQGVGPVMGGKSPASHPQHFP-----PRGFQSNHPHSGGFPRYRPPQG-MRYSYHPPPQP 1212
+ P+ SP + P P P+ + H P PP ++ + PP P
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
Query: 1213 SYHHY-----QRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPP 1253
Q P A P P P SPS P Q PPP
Sbjct: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 72.8 bits (177), Expect = 2e-12
Identities = 149/610 (24%), Positives = 196/610 (32%), Gaps = 124/610 (20%)
Query: 563 SRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVG 622
+R R+ G+ V P S+R + P E KS+ SS + S++ P
Sbjct: 168 ARRSRAAGTEVGLPR--PAPSARPRPPTEGPRKSV-------SSASEHSTTEPSPAARRR 218
Query: 623 TSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPV 682
S G G P + S P + P GP P HP +P
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSS------PARSGPSARGTPRA--------PAHPSQP- 263
Query: 683 QQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMG---------PHPGS----- 728
P G+ +LR P++ TP K L LS+ P P +
Sbjct: 264 ---------KPKGLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Query: 729 -LQLGQISGPSQ-DGSMYAPA-QFQPGFIP-PRHGGAPARPPDFPESSEIPPSHMYRSYK 784
L + PSQ S+ +P Q F+P P PP P + +PP
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ------ 367
Query: 785 YLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWT 844
A P P P P P H++ + PP PP
Sbjct: 368 ---------------APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP---- 408
Query: 845 EQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPE 904
Q+ F P P P A L PP+ P S +P + +P
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS----PSATPPPQAPP 464
Query: 905 MIAMQQLSSRVCPPGVP---YHPHQPAHPRLPGPFPQVAHPMSVTVSAP-KPALGNPGRA 960
+A L PP P P A P P FP A P S + S P P P +A
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA-PFSPSASLPMSPLATPPPQA 523
Query: 961 PENSEA---QEPENDQAEPLPGLEEKPPGVGTSEGV-----YLTQLPHPTPPLQTDCTRQ 1012
P A Q P + A P +PP G V L P P PP
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP-------P 576
Query: 1013 SSPQERETVGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGAL 1072
S GP+L SS + + ++G DS G AA D A A
Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRG-----YDSGPEGGAAASPPPDAELAACHPAA 631
Query: 1073 SENGVIGEASPCGSEGKGL-----GSSGSEKLLCPRGRTLQETMPCTGQNAATP------ 1121
G + G+ G L GS LC T+ ET G +ATP
Sbjct: 632 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC----TIYET---EGPESATPAPGALD 684
Query: 1122 PSTDPGLTGG 1131
P PG +GG
Sbjct: 685 PGPSPGTSGG 694
Score = 51.2 bits (121), Expect = 7e-06
Identities = 121/529 (22%), Positives = 165/529 (31%), Gaps = 101/529 (19%)
Query: 746 PAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGP 805
PA PG + PR G+P PP + P+ + RV A GA + P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPP------VTPAAL--------RVLGAA-----GAVGRKP 57
Query: 806 LGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCK 865
L G G + P + +R RPP SG P+ P
Sbjct: 58 LAERAG---GIGGATIPESAPRAGPTRTSRPPA--------SGRGERAPPAKNTSPGPVS 106
Query: 866 SAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPH 925
S G R P P G A V G + ++P+ A+ + R P P
Sbjct: 107 SPG-RASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSAGARRDTSGPTPGTPS 164
Query: 926 QPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPP 985
R +V P + P+P P P S + E+ EP P +P
Sbjct: 165 PAMARRSRAAGTEVGLPRPAPSARPRP----PTEGPRKSVSSASEHSTTEPSPAARRRPS 220
Query: 986 GVGTSEGVYLTQLPHPTPPLQTDCTR---------------QSSPQERETVGPELKSSSS 1030
G + L PL + Q P+ + + P +
Sbjct: 221 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 280
Query: 1031 ESADNCKAMKGKNPW--PSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEG 1088
+ A +P PS S+ P P+A ++ L + A+P
Sbjct: 281 KDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP-------------ATPPSQAT 327
Query: 1089 KGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPP-LYMPGLEYP 1147
LGS TLQ T +P +T P Q PP L +P L+ P
Sbjct: 328 TSLGSP-----------TLQATHSFLPSPPLSPLATPP-------PQAPPALALPPLQAP 369
Query: 1148 NSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYS-- 1205
S SP L SP + P P + + P PP +S
Sbjct: 370 PSPP---ASPPL----------SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416
Query: 1206 YHPPPQPSYHH-YQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPP 1253
PP PS Q P A P P P SPS P Q PPP
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465
Score = 43.5 bits (101), Expect = 0.002
Identities = 115/535 (21%), Positives = 167/535 (31%), Gaps = 107/535 (20%)
Query: 924 PHQPAHPRLPGPFPQVAHPMSVTVSAP--KPALGNPG-----RAPENSEAQEPENDQAEP 976
P P PR P P A + A KP G PE++ P P
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86
Query: 977 LPGLEEK-PPGVGTSEGVYLTQLPHPTPPLQTDCTRQ----------------------- 1012
G E+ PP TS G P +P + TR
Sbjct: 87 ASGRGERAPPAKNTSPG------PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140
Query: 1013 -------SSPQERETVGPELKSSSSESADNCKAMKGKN--PWPSDSSYPGPAAQGCVRDL 1063
S+ R+T GP + S A +A + P P+ S+ P P +G + +
Sbjct: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200
Query: 1064 STVADRGALSENGVIGEASPCGSEGKGLGSSGSEKLLCPRGRTLQETM-PCTGQNAATPP 1122
S+ ++ E SP G L P R+L + P + + P
Sbjct: 201 SSASEHSTT-------EPSPAARRRPSAGGG----LQRPASRSLSSSATPLSSPARSGPS 249
Query: 1123 STDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMG--GKSPASHPQ-HFP 1179
+ SQ P + L P ++P + P +G SP + P P
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALRPPQ------VTPPRKDAAPALGPLSSSPLATPSPSAP 303
Query: 1180 PRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRP---- 1235
P + P PP S P + H + +P + P + Q P
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS-PLATPPPQAPPALA 362
Query: 1236 LHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQN 1295
L P +P PPAS P P A SP +A+A + +
Sbjct: 363 LPPLQAPPSPPASPPLSP--------------------LATPSPQAPNALAVHLLQAPFS 402
Query: 1296 PGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSA 1355
P P + P SP + ++ SL+A PP S M S+
Sbjct: 403 P-PPSPPVQAPFSPPASPPVS---PSATPPSQAPPSLAAPPLQVPPSPPASPPMS-PSAT 457
Query: 1356 FPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALP----------PHHPGATQP 1400
PP + PP +P P + P+ ALP P P A+ P
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 72.0 bits (175), Expect = 4e-12
Identities = 46/138 (33%), Positives = 70/138 (50%), Gaps = 12/138 (8%)
Query: 404 LLAQGKELP-----PELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKA---HKD 455
LL +G E P P L N P E K + + ++KV V+KA H+
Sbjct: 38 LLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKV--VMKALWKHQF 95
Query: 456 SWPFLEPVD--ESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKY 513
+WPF +PVD + P+Y++IIK PMD+ +++++L Y E + D TMF NC Y
Sbjct: 96 AWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIY 155
Query: 514 NGESSEYTKMSDNLERCF 531
N + + M+ LE+ F
Sbjct: 156 NKPTDDIVLMAQTLEKIF 173
Score = 71.2 bits (173), Expect = 7e-12
Identities = 81/358 (22%), Positives = 128/358 (35%), Gaps = 75/358 (20%)
Query: 408 GKELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESY 467
G+ + P L + + K L E + K L K +WPF +PVD S
Sbjct: 321 GRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASA 380
Query: 468 AP--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSE------ 519
+Y+ IIK PMD+S++++K+ Y +EF D++ MF NC KYN +
Sbjct: 381 LGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMAR 440
Query: 520 ---------YTKMSD----------------NLERCFHRAMMKHFPGEDGDTDEEFWIRE 554
Y KM D L + + + E +EE E
Sbjct: 441 KLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEE 500
Query: 555 DEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTR------------- 601
DE+ E+ S +H ++ + +Q + G P R
Sbjct: 501 DEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKA 560
Query: 602 -----RAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTF 656
RA + DD+ + +PP+ + G GG+ + P F
Sbjct: 561 EKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSG-----GGSAALG----------PSGF 605
Query: 657 GPLRGS-----DPATLYGSSGVPEPHPGEPVQQRQPFT----MQPPVGINSLRGPRLG 705
GP GS AT +P + E ++ +P + Q + IN L G +LG
Sbjct: 606 GPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLG 663
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 72.0 bits (175), Expect = 4e-12
Identities = 46/138 (33%), Positives = 70/138 (50%), Gaps = 12/138 (8%)
Query: 404 LLAQGKELP-----PELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKA---HKD 455
LL +G E P P L N P E K + + ++KV V+KA H+
Sbjct: 38 LLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKV--VMKALWKHQF 95
Query: 456 SWPFLEPVD--ESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKY 513
+WPF +PVD + P+Y++IIK PMD+ +++++L Y E + D TMF NC Y
Sbjct: 96 AWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIY 155
Query: 514 NGESSEYTKMSDNLERCF 531
N + + M+ LE+ F
Sbjct: 156 NKPTDDIVLMAQTLEKIF 173
Score = 71.2 bits (173), Expect = 7e-12
Identities = 81/358 (22%), Positives = 128/358 (35%), Gaps = 75/358 (20%)
Query: 408 GKELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESY 467
G+ + P L + + K L E + K L K +WPF +PVD S
Sbjct: 321 GRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASA 380
Query: 468 AP--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSE------ 519
+Y+ IIK PMD+S++++K+ Y +EF D++ MF NC KYN +
Sbjct: 381 LGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMAR 440
Query: 520 ---------YTKMSD----------------NLERCFHRAMMKHFPGEDGDTDEEFWIRE 554
Y KM D L + + + E +EE E
Sbjct: 441 KLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEE 500
Query: 555 DEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTR------------- 601
DE+ E+ S +H ++ + +Q + G P R
Sbjct: 501 DEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKA 560
Query: 602 -----RAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTF 656
RA + DD+ + +PP+ + G GG+ + P F
Sbjct: 561 EKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSG-----GGSAALG----------PSGF 605
Query: 657 GPLRGS-----DPATLYGSSGVPEPHPGEPVQQRQPFT----MQPPVGINSLRGPRLG 705
GP GS AT +P + E ++ +P + Q + IN L G +LG
Sbjct: 606 GPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLG 663
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 71.2 bits (173), Expect = 7e-12
Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 13/122 (10%)
Query: 412 PPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVD--ESYAP 469
PPE+S+ P + +KT L + + V+ + H+ +WPF +PVD + P
Sbjct: 23 PPEVSN-----PSKPGRKTNQLQYMQN------VVVKTLWKHQFAWPFYQPVDAIKLNLP 71
Query: 470 NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLER 529
+Y++IIK PMD+ +++K+L Y + E + D TMF NC YN + + M+ LE+
Sbjct: 72 DYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEK 131
Query: 530 CF 531
F
Sbjct: 132 IF 133
Score = 63.5 bits (153), Expect = 1e-09
Identities = 41/131 (31%), Positives = 62/131 (47%), Gaps = 9/131 (6%)
Query: 412 PPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDS---WPFLEPVDESYA 468
PP+ D P KK K L + +L + + K + WPF +PVD
Sbjct: 288 PPKKDLEDGEVPQHAGKKGK----LSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEAL 343
Query: 469 P--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526
+Y+ IIK PMD+S++++K++G Y + F D++ MF NC KYN E M+
Sbjct: 344 ELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARK 403
Query: 527 LERCFHRAMMK 537
L+ F K
Sbjct: 404 LQDVFEMRFAK 414
Score = 32.7 bits (73), Expect = 2.7
Identities = 41/195 (21%), Positives = 88/195 (45%), Gaps = 19/195 (9%)
Query: 182 RESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQG 241
++ E +K + + K+ P K+ Q++ ++K + A + G Q
Sbjct: 502 KDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASAS- 560
Query: 242 TWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAEL 301
+EEE + S+ E+ L + +L E L + ++I + + + +
Sbjct: 561 -----YDSEEEEEGLPMSYDEKRQL-SLDINRLPGEK-LGRVVHIIQSR----EPSLRDS 609
Query: 302 HPRWMS-DHLSIKP--VKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK 358
+P + D ++KP +++ E V + ++K++RK + A K+E L +E+K
Sbjct: 610 NPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEE----LAQEKK 665
Query: 359 RELEEKVKAVEGMCS 373
+ELE++++ V G S
Sbjct: 666 KELEKRLQDVSGQLS 680
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 70.9 bits (172), Expect = 9e-12
Identities = 33/87 (37%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 446 VLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKT 505
V+++V+ H DSWPFL+ V + P+YY IIK P+ ++ + +K+N Y EF++D++
Sbjct: 1410 VVELVR-HDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL 1468
Query: 506 MFRNCRKYNGESSEYTKMSDNLERCFH 532
MF NC +YN ++ K L+ FH
Sbjct: 1469 MFSNCFEYNPRNTSEAKAGTRLQAFFH 1495
Score = 35.8 bits (81), Expect = 0.32
Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 46/160 (28%)
Query: 199 KRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEWRQVTE 258
+RRGRPPKR + +E ++ KQ S S+
Sbjct: 274 RRRGRPPKRIHISQEDNVANKQTLASYRSK------------------------------ 303
Query: 259 SFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQE 318
+ +ER L +++ K L+ + K KR + E + D K K+E
Sbjct: 304 ATKERDKLLKQEEMKSLAFE---------KAKLKREKADALEAKKKEKED----KEKKRE 350
Query: 319 ETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK 358
E + E+ K+KEE+E ++ ++KE+E++ +E+RK
Sbjct: 351 ELKKIVEEERLKKKEEKERLKV---EREKEREKLREEKRK 387
Score = 32.0 bits (71), Expect = 4.6
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 9/64 (14%)
Query: 315 VKQEETPVLTRIEKQKRKEEEEERQILLAVQ-----KKEQEQMLKEERKRE----LEEKV 365
+K+E+ L +K+K +E++ ++ V+ KKE+++ LK ER++E EEK
Sbjct: 327 LKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKR 386
Query: 366 KAVE 369
K VE
Sbjct: 387 KYVE 390
Score = 31.2 bits (69), Expect = 7.8
Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 18/84 (21%)
Query: 276 SEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEE 335
+ DF+ + +++ Q + + KAE H ++E RI K+K ++ +
Sbjct: 598 TRDFIEDYVDILRQAKQEFRELKAEQH-------------RKEREEAAARIRKRKEEKLK 644
Query: 336 EERQILLAVQKKEQEQMLKEERKR 359
E+ Q + KE+++ LKE+ +R
Sbjct: 645 EQEQ-----KMKEKQEKLKEDEQR 663
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 70.9 bits (172), Expect = 9e-12
Identities = 33/87 (37%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 446 VLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKT 505
V+++V+ H DSWPFL+ V + P+YY IIK P+ ++ + +K+N Y EF++D++
Sbjct: 1442 VVELVR-HDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL 1500
Query: 506 MFRNCRKYNGESSEYTKMSDNLERCFH 532
MF NC +YN ++ K L+ FH
Sbjct: 1501 MFSNCFEYNPRNTSEAKAGTRLQAFFH 1527
Score = 35.8 bits (81), Expect = 0.32
Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 46/160 (28%)
Query: 199 KRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEWRQVTE 258
+RRGRPPKR + +E ++ KQ S S+
Sbjct: 274 RRRGRPPKRIHISQEDNVANKQTLASYRSK------------------------------ 303
Query: 259 SFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQE 318
+ +ER L +++ K L+ + K KR + E + D K K+E
Sbjct: 304 ATKERDKLLKQEEMKSLAFE---------KAKLKREKADALEAKKKEKED----KEKKRE 350
Query: 319 ETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK 358
E + E+ K+KEE+E ++ ++KE+E++ +E+RK
Sbjct: 351 ELKKIVEEERLKKKEEKERLKV---EREKEREKLREEKRK 387
Score = 32.0 bits (71), Expect = 4.6
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 9/64 (14%)
Query: 315 VKQEETPVLTRIEKQKRKEEEEERQILLAVQ-----KKEQEQMLKEERKRE----LEEKV 365
+K+E+ L +K+K +E++ ++ V+ KKE+++ LK ER++E EEK
Sbjct: 327 LKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKR 386
Query: 366 KAVE 369
K VE
Sbjct: 387 KYVE 390
Score = 31.2 bits (69), Expect = 7.8
Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 18/84 (21%)
Query: 276 SEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEE 335
+ DF+ + +++ Q + + KAE H ++E RI K+K ++ +
Sbjct: 630 TRDFIEDYVDILRQAKQEFRELKAEQH-------------RKEREEAAARIRKRKEEKLK 676
Query: 336 EERQILLAVQKKEQEQMLKEERKR 359
E+ Q + KE+++ LKE+ +R
Sbjct: 677 EQEQ-----KMKEKQEKLKEDEQR 695
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 69.3 bits (168), Expect = 3e-11
Identities = 197/882 (22%), Positives = 283/882 (32%), Gaps = 129/882 (14%)
Query: 558 REKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQ-----SS 612
R+ RAG GG+ + PE + R G S P R P+SG + +
Sbjct: 55 RKPLAERAGGIGGATI------PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN 108
Query: 613 SSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSG 672
+S P G ++G PL G A + T P R + A +
Sbjct: 109 TSPGPVSSPGRASGTTRPGPLGQKGLRISA---EETVARGKATEAPKRSALSAGARRDTS 165
Query: 673 VPEPHPGEPVQQRQPFTMQPPVGIN----SLRGPRLGTPEEKQMCGGLTHLSNMGPHPGS 728
P P P R+ VG+ S R PR T ++ + S P P +
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAA 224
Query: 729 LQLGQISGPSQDGSMYAPAQFQ------PGFIPPRHGGAPARPPDFPESSEIPPSHMYRS 782
+ PS G + PA P P R G + P P P ++
Sbjct: 225 RRR-----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 783 YKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQ 842
+ P D P LGP S P ++ P P N
Sbjct: 280 LR---------------PPQVTPPRKDAAPALGP-LSSSPLATPSPSGTKARPVPPPDNA 323
Query: 843 WTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDS 902
T LP +P S + P L PP AP SL P+ M +
Sbjct: 324 ATP----LPATLPPSPPLATPLP-----LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374
Query: 903 PEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPG-RAP 961
P M A L + PP PH P L P P++++ +LG+P +A
Sbjct: 375 PPMQAPPSLQT--IPP--IQVPHSLTSPSLQAP----PSPLALSSLQATTSLGSPTLQAT 426
Query: 962 ENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHP-TPPLQTDCTRQSSPQERET 1020
+ P QA +P L P +PPLQT + SP
Sbjct: 427 HSFLTMSPRQTQASLTS--PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL 484
Query: 1021 VGPELKSSSSESADNCKAMKGK---NPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGV 1077
L++ SS ++ + +A P + SS P+ Q L+T EN
Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP-----LENLP 539
Query: 1078 IGEASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFP 1137
P + L + E CP PC Q +P +T P T +++ P
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPA--------PCPLQAPPSPLTTPPPETPSSIATPP 591
Query: 1138 PLYMPGLEYPNS-----------AAHYHISPGLQGVGPVMGGKSPASHPQHFP-----PR 1181
P P L P A +P + P+ SP + P P P+
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
Query: 1182 GFQSNHPHSGGFPRYRPPQG-MRYSYHPPPQPSYHHY-----QRTPYYACPQSFSDWQRP 1235
+ H P PP ++ + PP P Q P A P P
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711
Query: 1236 LHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQN 1295
P SPS P Q PPP + S ++ + T P R+ + A P
Sbjct: 712 ASPPMSPSATPPPQAPPPLAA-PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP----- 765
Query: 1296 PGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSA 1355
++ P SP L + + A+ L P P +S G +
Sbjct: 766 -----------LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP--GQAP 812
Query: 1356 FPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGA 1397
F P S L P TP A P ++P+ +PP P +
Sbjct: 813 FSP-SASLPMSPLATPPPQA----PPVLAAPLLQVPPSPPAS 849
Score = 63.2 bits (152), Expect = 2e-09
Identities = 153/641 (23%), Positives = 200/641 (31%), Gaps = 88/641 (13%)
Query: 580 PEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSS-TQPPREVGTSNGRGFSHPLHCG-G 637
P S Q G +L T + Q+ +S T P R T S PL
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD---SPPLQAPLS 462
Query: 638 TPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGIN 697
P+ P + PAV PL S P T++ + P M P +
Sbjct: 463 LPASPPLQTSLSPAV----SPL--SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS 516
Query: 698 SLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMY---APAQFQPGFI 754
SL P L TP L +L ++ P P ++ P + P Q P +
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576
Query: 755 ---PPRHGGAPARPP-DFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATN--QGPLGP 808
PP + A PP P + PP S A Q P P
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636
Query: 809 DEKPHLGP--GPSHQ-PRTLG-HVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPC 864
P L P PS Q P L H++ + PP PP Q+ F P P P
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP----VQAPFSPPASPPVSPSATPP 692
Query: 865 KSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPP-GVPYH 923
A L PP+ P S +P + +P +A L PP P
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMS----PSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
Query: 924 PHQPAHPRLP----------GPFPQVAHPMSVTVSAP---KPALGNP-----GRAPENSE 965
P PR+P P P + PMS P PAL P P +
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808
Query: 966 AQEPENDQAE-PLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPE 1024
Q P + A P+ L PP L Q+P P+PP +P+ T GP+
Sbjct: 809 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPASPTL---QAPRRPPTPGPD 864
Query: 1025 LKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPC 1084
+S S P P S P G L+ + ++P
Sbjct: 865 ----TSVSGPRLTLALAPGPPPPPSRSPSSTLSG-----------PDLAGHSSSATSTPE 909
Query: 1085 GSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPG- 1143
G G G P L P PP G G + +PP PG
Sbjct: 910 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL-PWPPATGPGS 968
Query: 1144 ---------LEYPNSAAHYHISPGLQGVGP---VMGGKSPA 1172
E P SA +PG GP GGK+ A
Sbjct: 969 ADGLCTIYETEGPESATP---APGALDPGPSPGTSGGKAAA 1006
Score = 55.1 bits (131), Expect = 5e-07
Identities = 162/746 (21%), Positives = 226/746 (30%), Gaps = 145/746 (19%)
Query: 746 PAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGP 805
PA PG + PR G+P PP ++ + + + R A G G G
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAA----LRVLGAAGAVGRKPLAERAGGIG----GA 68
Query: 806 LGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCK 865
P+ P GP R+ G + RPP G PP K
Sbjct: 69 TIPESAPRAGP-----TRSAGTSSRNPASRPP----------------ASGRGERAPPAK 107
Query: 866 SAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPH 925
+ P PV +P G G +G I+ ++ +R P
Sbjct: 108 NT----SPGPVSSPGRASGTTRPGPLGQKG--------LRISAEETVARGKATEAPKRSA 155
Query: 926 QPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPP 985
A R S P P +P A S A E P P +PP
Sbjct: 156 LSAGARR-------------DTSGPTPGTPSPAMA-RRSRAAGTEVGLPRPAPSARPRPP 201
Query: 986 GVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNCKAMKGKNPW 1045
G + V T P + + R + G L+ +S S +
Sbjct: 202 TEGPRKSVSSASEHSTTEP-------SPAARRRPSAGGGLQRPASRSLSSSATPL----- 249
Query: 1046 PSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGSSGSEKLLCPRGR 1105
S + GP+A+G R A P + KGL + ++ PR
Sbjct: 250 -SSPARSGPSARGTPR-----------------APAHPSQPKPKGLQALRPPQVTPPR-- 289
Query: 1106 TLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPV 1165
++ P G +++P +T P +G PP P++AA P P
Sbjct: 290 --KDAAPALGPLSSSPLAT-PSPSGTKARPVPP--------PDNAA--TPLPATLPPSPP 336
Query: 1166 MGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYAC 1225
+ P + P P Q+ P PP S PP + Q P
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP-----SMTTPPMQAPPSLQTIPPIQV 391
Query: 1226 PQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAA---LTSPTRM 1282
P S + P+ Q PP S A SL G TL A LT R
Sbjct: 392 PHSLTS--------------PSLQAPPSPLALSSLQATTSL-GSPTLQATHSFLTMSPRQ 436
Query: 1283 DAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLS-------AS 1335
+ P+ + P+ L + P SP L A + S L+ +S
Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASPP--LQTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 1336 EYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHP 1395
+ PLS S PP PP PAS P + P A PP
Sbjct: 495 LASHSPQAPLS------SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 1396 GATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQ 1455
+ E P + T S I P + P + P+Q
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ--APPALASPPLQGL 606
Query: 1456 ASFPKTPTAATSQEEVPPHKPPTLPL 1481
S P +P A PP PP L L
Sbjct: 607 PSPPLSPLATP-----PPQAPPXLAL 627
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 68.6 bits (166), Expect = 4e-11
Identities = 110/419 (26%), Positives = 140/419 (33%), Gaps = 57/419 (13%)
Query: 580 PEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREV------GTSNGRGFSHPL 633
P+G ++ Q P GK P P G +Q PP + G + +G P
Sbjct: 41 PQGGNKPQGPPSPPGKPQGP----PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 96
Query: 634 HCGGTPSQAPFLNQMR--PAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQ 691
G P Q R P P P G+ P P P PG+P
Sbjct: 97 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG-------PPPPPGKPQGP------- 142
Query: 692 PPVGINSLRGPRL-GTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQ 750
PP G N +GP G P+ G S+ P PG Q G +Q P +
Sbjct: 143 PPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP-PGKPQGPPPQGGNQPQGP-PPPPGK 200
Query: 751 PGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATN-QGPLGPD 809
P PP+ G P PP + PP +S + G QGP P
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPP 260
Query: 810 EKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGH 869
KP GP P + G + PP P +S P G P P G+
Sbjct: 261 GKPQ-GPPPQGGNKPQGPPPPGKPQGPP-PQGGSKSRSSRSPPGKPQG-----PPPQGGN 313
Query: 870 RLQPPPVPAPSSLFGAPAQALRGVQGGD---SMMDSPEMIAMQQLSSRVCPPGVPYHPHQ 926
+ Q PP P P G P Q QG P + S+R PPG P P Q
Sbjct: 314 QPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR-SPPGKPQGPPQ 371
Query: 927 PAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPP 985
GP P PA GNP + P+ A +P+ P G +PP
Sbjct: 372 QEGNNPQGP--------------PPPAGGNP-QQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 63.5 bits (153), Expect = 1e-09
Identities = 107/430 (24%), Positives = 142/430 (33%), Gaps = 84/430 (19%)
Query: 851 PHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQ 910
P G P G G++ Q PP P P G P Q GG+ P
Sbjct: 36 PQGAPPQG---------GNKPQGPPSP-PGKPQGPPPQ------GGNQPQGPPP------ 73
Query: 911 LSSRVCPPGVPYHP-----HQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSE 965
PPG P P ++P P PG PQ P +P+ G P + P
Sbjct: 74 ------PPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGDKSRSPRSPPGKP-QGPPPQG 125
Query: 966 AQEPENDQAEPLPGLEEKPPGVGTS--EGVYLTQLPHPTPPLQTDCTRQSSPQERETVGP 1023
+P+ P PG + PP G + +G P PP + +R S + GP
Sbjct: 126 GNQPQGPP--PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 1024 ELKSSSSESADNCKAMKGKNPWPSDSSYP----------GPAAQGCVRDLSTVADRGALS 1073
+ + K + P P + P GP QG + S + G
Sbjct: 184 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243
Query: 1074 ENGVIGEASPCGSE---GKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTG 1130
G P G GK G P+G + P G+ PP G +
Sbjct: 244 GPPPQGGNQPQGPPPPPGKPQGPP-------PQGGNKPQGPPPPGKPQGPPPQ---GGSK 293
Query: 1131 GTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNH-PH 1189
S+ PP G P QG G P PQ PP+G P
Sbjct: 294 SRSSRSPPGKPQG-------------PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340
Query: 1190 SGGFPRYRPPQG---MRYSYHPPPQPSYHHYQR--TPYYACPQSFSDWQRPLHPQGSPSG 1244
G P+ PPQG R + PP +P Q P P + + P PQ P+G
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGN---PQQPQAPPAG 397
Query: 1245 PPASQPPPPR 1254
P P PP+
Sbjct: 398 QPQGPPRPPQ 407
Score = 57.0 bits (136), Expect = 1e-07
Identities = 81/318 (25%), Positives = 101/318 (31%), Gaps = 49/318 (15%)
Query: 751 PGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGPLGPDE 810
P PP+ G P PP P + PP G QGP P
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPP-------------------QGGNQPQGPPPPPG 76
Query: 811 KPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHR 870
KP GP P + G + P PP +S P G P P G++
Sbjct: 77 KPQ-GPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQG-----PPPQGGNQ 128
Query: 871 LQPPPVPAPSSLFGAPAQALRGVQG--GDSMMDSPEMIAMQQLSSRVCPPGVPYHP---- 924
Q PP P P G P Q QG P + S PPG P P
Sbjct: 129 PQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG 187
Query: 925 -HQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEK 983
+QP P P PQ P P G P P + ++ A PG +
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG---DNKSQSARSPPGKPQG 244
Query: 984 PPGVGTSEGVYLTQLPHPT------PPLQTDCTRQSSPQERETVGPELKSSSSESADNCK 1037
PP G ++ Q P P PP Q Q P + GP + S +
Sbjct: 245 PPPQGGNQ----PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 1038 AMKGKNPWPSDSSYP-GP 1054
K + P P + P GP
Sbjct: 301 PGKPQGPPPQGGNQPQGP 318
Score = 53.1 bits (126), Expect = 2e-06
Identities = 85/303 (28%), Positives = 98/303 (32%), Gaps = 58/303 (19%)
Query: 1112 PCTGQNAATPPSTDPGLT------GGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPV 1165
P G N P + PG GG Q PP P P P QG G
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPP---PPPGKPQG-------PPPQG-GNK 88
Query: 1166 MGGKSPASHPQHFPPRGFQSNHPHS-GGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYA 1224
G P PQ PP+G +S P S G P+ PPQG PPP P P
Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG------KPQGP 142
Query: 1225 CPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFS--DKNAMASLQGCETLNAALTSPTRM 1282
PQ + Q P P G P GPP RS S K QG P +
Sbjct: 143 PPQGGNKPQGP-PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201
Query: 1283 DAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTP 1342
+ N Q P P +P+ P D K QS+ S G P
Sbjct: 202 QGPPPQGGNKPQGPPPP--------GKPQGPPPQGD-------NKSQSARSPPGKPQGPP 246
Query: 1343 PPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQPNG 1402
P G PP PP PQ P P+ + P PP P P G
Sbjct: 247 P-----QGGNQPQGPP-------PPPGKPQGP----PPQGGNKPQGPPPPGKPQGPPPQG 290
Query: 1403 LSQ 1405
S+
Sbjct: 291 GSK 293
Score = 51.6 bits (122), Expect = 6e-06
Identities = 88/359 (24%), Positives = 109/359 (30%), Gaps = 78/359 (21%)
Query: 1135 QFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNH-PHSGGF 1193
Q PP P S P QG G P PQ PP+G P G
Sbjct: 99 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158
Query: 1194 PRYRPPQG---MRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQ- 1249
P+ PPQG R S PP +P Q P PQ + Q P P G P GPP
Sbjct: 159 PQGPPPQGDNKSRSSRSPPGKP-----QGPP----PQGGNQPQGPPPPPGKPQGPPPQGG 209
Query: 1250 -----PPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLD 1304
PPPP K QG +A + P + + N Q P P K
Sbjct: 210 NKPQGPPPP-----GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 264
Query: 1305 ----ESMERPESPKEFLDLDNH--NAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPP 1358
+ +P+ P +K +SS S G PP G PP
Sbjct: 265 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP-----QGGNQPQGPP 319
Query: 1359 HSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLG 1418
PP PQ P P+ + P PP P P G
Sbjct: 320 P-------PPGKPQGPP----PQGGNKPQGPPPPGKPQGPPPQG---------------- 352
Query: 1419 HFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPP 1477
G++S + P G P Q + + P+ P P PP
Sbjct: 353 ----------GSKS------RSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Score = 38.9 bits (89), Expect = 0.037
Identities = 55/225 (24%), Positives = 65/225 (28%), Gaps = 44/225 (19%)
Query: 1192 GFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPP----- 1246
G P+ PPQG PP P P PQ + Q P P G P GPP
Sbjct: 34 GNPQGAPPQGGNKPQGPPSPPG------KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 87
Query: 1247 -ASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQN--------PG 1297
PPPP QG SP P G N PG
Sbjct: 88 KPQGPPPP----------GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 137
Query: 1298 PEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFP 1357
+ + +P+ P +S S S PP G P
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRS------PPGKPQGP-------P 184
Query: 1358 PHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQPNG 1402
P GPP P +P P+ + P PP P P G
Sbjct: 185 PQGGNQPQGPPPPPGKPQGP-PPQGGNKPQGPPPPGKPQGPPPQG 228
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 68.6 bits (166), Expect = 4e-11
Identities = 46/143 (32%), Positives = 76/143 (53%), Gaps = 6/143 (4%)
Query: 403 WLLAQGKELP-PELSH-LDPNSPMREEKKTKDLFELDD-DFTAMYKVLDVVKAHKDSWPF 459
W+ ++L PE+ + D S E+KKT+ L +L D ++L + H+ S F
Sbjct: 865 WICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAF 924
Query: 460 LEPVDESYAPNYYQIIKAPMDISSMEKKLNG--GLYCTKEEFVNDMKTMFRNCRKYNGES 517
+PV + P+YY+IIK PMD+S+++K+L +Y E+FV D + +F+NC ++N
Sbjct: 925 QDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD 983
Query: 518 SEYTKMSDNLERCFHRAMMKHFP 540
SE LE F + +P
Sbjct: 984 SEVANAGIKLENYFEELLKNLYP 1006
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 68.6 bits (166), Expect = 4e-11
Identities = 46/143 (32%), Positives = 76/143 (53%), Gaps = 6/143 (4%)
Query: 403 WLLAQGKELP-PELSH-LDPNSPMREEKKTKDLFELDD-DFTAMYKVLDVVKAHKDSWPF 459
W+ ++L PE+ + D S E+KKT+ L +L D ++L + H+ S F
Sbjct: 831 WICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAF 890
Query: 460 LEPVDESYAPNYYQIIKAPMDISSMEKKLNG--GLYCTKEEFVNDMKTMFRNCRKYNGES 517
+PV + P+YY+IIK PMD+S+++K+L +Y E+FV D + +F+NC ++N
Sbjct: 891 QDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD 949
Query: 518 SEYTKMSDNLERCFHRAMMKHFP 540
SE LE F + +P
Sbjct: 950 SEVANAGIKLENYFEELLKNLYP 972
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 67.8 bits (164), Expect = 8e-11
Identities = 181/761 (23%), Positives = 238/761 (31%), Gaps = 179/761 (23%)
Query: 581 EGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSN--GRGFSHPLHCGGT 638
EG QP + G + PT S+ D +SS+ PP G + G +
Sbjct: 359 EGEENPDQPTDPGAGAEIPT----STADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDE 414
Query: 639 PSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQP------ 692
P+ + + P GP ++ T+Y G P GE Q+ +P ++P
Sbjct: 415 NYYDPYYDPT--SSPSEIGPGMPANQDTIYEGIGGPR---GEKGQKGEPAIIEPGMLIEG 469
Query: 693 ---PVGINSLRGP--------RLGTPEEKQMCG--GLTHLSNMGPHPGSL-----QLGQI 734
P G L GP ++G P E+ G GL + PG++ + G
Sbjct: 470 PPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGG 529
Query: 735 SGPSQDGSMYAPAQFQ------------------------PGFI-PPRHGGAPARP---- 765
G M + + Q PG + PP GG P
Sbjct: 530 GDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVG 589
Query: 766 PDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQ-GPLG----------PDEKPHL 814
P P + PP + R A +G G Q GP G P EK H
Sbjct: 590 PQGPRGVQGPPGPAGKP----GRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645
Query: 815 G-PGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQP 873
G PGPS P PP + + P G+P R G P
Sbjct: 646 GDPGPSGPPG------------PPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKG----P 689
Query: 874 PPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPR-- 931
P P P + G Q G +G V P G P P Q +P
Sbjct: 690 PGPPGPPGVTGMDGQP--GPKGN------------------VGPQGEPGPPGQQGNPGAQ 729
Query: 932 -LPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPPGVGTS 990
LPGP + P K LG PG P A P PG +E PPG
Sbjct: 730 GLPGPQGAIGPP------GEKGPLGKPG-LPGMPGADGPPGH-----PG-KEGPPGEKGG 776
Query: 991 EGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNCKAMKGKNPWPSDSS 1050
+G P P P+ P R G AD + +KG +
Sbjct: 777 QGP-----PGPQGPI-------GYPGPRGVKG----------ADGIRGLKGTKGEKGEDG 814
Query: 1051 YPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGSSGSEKLLCPRGRTLQET 1110
+PG D+ DRG + G GE P G +G+G G +G L P G +
Sbjct: 815 FPGFKG-----DMGIKGDRGEIGPPGPRGEDGPEGPKGRG-GPNGDPGPLGPPGEKGKLG 868
Query: 1111 MP-CTGQNAATPPSTDPGLTG-----------GTVSQFPPLYMPGLEYPNSAAHYHISPG 1158
+P G P G G GT + P G P G
Sbjct: 869 VPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITG 928
Query: 1159 LQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQ 1218
G GG PA P P G Q G PP HP +
Sbjct: 929 KPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 988
Query: 1219 RT-----PYYACPQSFSDWQRPLHPQG--SPSGPPASQPPP 1252
+T P PQ + P+ +G P GPP Q P
Sbjct: 989 KTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029
Score = 62.0 bits (149), Expect = 4e-09
Identities = 184/724 (25%), Positives = 224/724 (30%), Gaps = 124/724 (17%)
Query: 578 RDPEGSSRKQQPMENGG---KSLPPTRRAPSS--GDDQSSSSTQPPREVGTSNGRGFSHP 632
R P G + K P N G + PP R P+ G PP G G HP
Sbjct: 921 RGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPG--HP 978
Query: 633 LHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQP 692
G T Q P PG GP + G G P P PG P +Q P
Sbjct: 979 GQRGETGFQG---KTGPPGPPGVVGPQGPTGETGPMGERGHPGP-PGPPGEQGLPGLAGK 1034
Query: 693 --------PVGINSLRGPR--LGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGS 742
P G+ GP G P ++ + G + L G G P + G
Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094
Query: 743 MYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATN 802
A P IP R G P PP P+ G GA
Sbjct: 1095 AGAAG---PIGIPGRPG--PQGPPG--------PA------------------GEKGAPG 1123
Query: 803 Q-GPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSS---- 857
+ GP GP + L GP P G P PP + ++ G S
Sbjct: 1124 EKGPQGPAGRDGL-QGPVGLPGPAG---------PVGPPGEDGDKGEIGEPGQKGSKGDK 1173
Query: 858 GYMRPPCKSAGHRLQPPPVPAPSSLFGAPA----QALRGVQGGDSMMDSPEMIAMQQLSS 913
G PP + P P PS G P Q L G +G + P L
Sbjct: 1174 GEQGPPGPTGPQG--PIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQG 1231
Query: 914 RVCPPGVPYHPH---QPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPE 970
PPG Q P PGP P + P +GNPG E E E
Sbjct: 1232 LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGE-- 1289
Query: 971 NDQAEP-LPGLEEKPPG-------VGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVG 1022
EP LPG E PPG G S P P P D + S
Sbjct: 1290 --AGEPGLPG-EGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD 1346
Query: 1023 PELKSSSSESA-DNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEA 1081
P + D KG + P + PGP + G + G G A
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE--------PGPSGPPGKRGPPGPA 1398
Query: 1082 SPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTG--GTVSQFPPL 1139
P G +G+ G+ G L P G+ T P Q A P D GL G G V +
Sbjct: 1399 GPEGRQGE-KGAKGEAGLEGPPGK----TGPIGPQGAPGKPGPD-GLRGIPGPVGE---Q 1449
Query: 1140 YMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHP---QHFPPRGFQSNH-----PHSG 1191
+PG P+ PGL G+ G K HP P G Q P
Sbjct: 1450 GLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1509
Query: 1192 GFPRYRPPQGMRYSYHP--PPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQ 1249
G + QG+ P PP P P P+ P P+G P
Sbjct: 1510 GSSGPKGEQGITGPSGPIGPPGP-----PGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPG 1564
Query: 1250 PPPP 1253
PP P
Sbjct: 1565 PPGP 1568
Score = 33.1 bits (74), Expect = 2.0
Identities = 90/390 (23%), Positives = 110/390 (28%), Gaps = 105/390 (26%)
Query: 579 DPEGSSRKQQPMENGGKSLP-------PTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSH 631
+P K +P E G LP P G+ S + PP G G
Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK- 1335
Query: 632 PLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVP----------EPHPGEP 681
G+P F P PG GP P G G P EP P P
Sbjct: 1336 -----GSPGPVGFPGD--PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP 1388
Query: 682 VQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDG 741
+R P P G +G + G E + G +GP G P DG
Sbjct: 1389 PGKRGP---PGPAGPEGRQGEK-GAKGEAGLEGPPGKTGPIGPQ------GAPGKPGPDG 1438
Query: 742 SMYAPAQFQPGFIPPRHGGAPARP-PDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGA 800
P P G P P PD P
Sbjct: 1439 LRGIPG-------PVGEQGLPGSPGPDGPP------------------------------ 1461
Query: 801 TNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYM 860
GP+GP P L G S GH ++ PP EQ G+P
Sbjct: 1462 ---GPMGPPGLPGL-KGDSGPKGEKGHPGLIGLIGPP------GEQGEKGDRGLPGPQGS 1511
Query: 861 RPPCKSAGHRLQPPPV--PAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPP 918
P G P+ P P L G P +G +G S P
Sbjct: 1512 SGPKGEQGITGPSGPIGPPGPPGLPGPPGP--KGAKGS---------------SGPTGPK 1554
Query: 919 GVPYHPHQPAHPRLPGPFPQVAHPMSVTVS 948
G HP P P PG +V P+ + S
Sbjct: 1555 GEAGHPGPPGPPGPPG---EVIQPLPIQAS 1581
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 65.9 bits (159), Expect = 3e-10
Identities = 129/502 (25%), Positives = 167/502 (33%), Gaps = 96/502 (19%)
Query: 595 KSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPG 654
K + + PSSG P + + +GF P PSQ +N + PG
Sbjct: 567 KQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQP-----HPSQQMPMNMAQMGPPG 621
Query: 655 TFGPLRGSDPATLYGSSGVP--------------EPHPGEPVQQRQPFTMQPPVGINSLR 700
G R P G G P + G P +P M P G+
Sbjct: 622 PQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHP 681
Query: 701 GPR-----LGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIP 755
GP G P + G H+ GP +G P G + P
Sbjct: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG-------P 734
Query: 756 PRHGGAPARPPDFPESSEIPPS-HMYRSYKYLNRVHSAVWNGNHGATN----QGPLGPDE 810
P G + P P + PP H + + V G N QGP GP E
Sbjct: 735 P--GTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRE 792
Query: 811 KPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHR 870
GP+ Q +GH + MR P PP G L HG MR P + G
Sbjct: 793 NQ----GPAPQGMIMGH--PPQEMRGPHPPG------GLLGHGPQE---MRGPQEIRG-- 835
Query: 871 LQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPE-MIAMQQLSSRVCPPGVPYHPHQPA- 928
+Q PP P P Q LRG G S P+ + PPG P PA
Sbjct: 836 MQGPP---PQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPG-PQGQQNPAR 891
Query: 929 --HPRL-PGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEK-- 983
HP P PF Q P+ LG+ RAP N E Q +PGL ++
Sbjct: 892 GPHPSQGPIPFQQQKTPL----------LGDGPRAPFNQEGQ--STGPPPLIPGLGQQGA 939
Query: 984 ----PP-----GVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESAD 1034
PP G G ++G H P+ QS E GPE
Sbjct: 940 QGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEH---GPE--RGPFRGGQ 994
Query: 1035 NCKA---MKGKNP-WPSDSSYP 1052
+C+ +G +P +P D S P
Sbjct: 995 DCRGPPDRRGPHPDFPDDFSRP 1016
Score = 45.8 bits (107), Expect = 3e-04
Identities = 151/643 (23%), Positives = 190/643 (29%), Gaps = 155/643 (24%)
Query: 580 PEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTP 639
P+G R P G PP + SSG PP G +G P G
Sbjct: 674 PQGMQRHPGPHGPLGPQGPPGPQG-SSGPQGHMGPQGPPGPQGHIGPQGPPGPQ--GHLG 730
Query: 640 SQAPFLNQMRPAVPGTFGPLRGSDPATLYG---SSGVPEPHPGEPVQQRQPFTMQPPVGI 696
Q P Q PG G P + G S G+ P P+ P MQ P G
Sbjct: 731 PQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGP 790
Query: 697 NSLRGPRLGTPEEKQMCGGLTHLSNMGPHP-------------GSLQLGQISGPSQDGSM 743
+G P + M G GPHP G ++ + GP GSM
Sbjct: 791 RENQG-----PAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSM 845
Query: 744 YAPAQF--------------QPGFIPPRHGG--------APARPPDFPESSEIPPSHMYR 781
P Q Q PP GG P P S+ P +
Sbjct: 846 LGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQ 905
Query: 782 SYKYLNRVHSAVWNGNHGATNQGPLGP--------DEKPHLGPGPSHQPRTLGHVMDSRV 833
L A +N +T PL P P L PG P + DSR
Sbjct: 906 KTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGP----NKGDSR- 960
Query: 834 MRPPVPPNQWT--------EQSGFLPHGVPSSGYMR-------PPCKSAGHRLQP----- 873
PPN EQSG HG P G R PP + H P
Sbjct: 961 ----GPPNHHMGPMSERRHEQSGGPEHG-PERGPFRGGQDCRGPPDRRGPHPDFPDDFSR 1015
Query: 874 PPVPAPSSLFGAPAQALRG-----------VQGGDSMMDSPEMIAMQQLSSRVCP----- 917
P P FG + G +GG P+ + R
Sbjct: 1016 PDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG 1075
Query: 918 ------PGVPYHPHQPAHPRLPG----PFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQ 967
PG P P PR G F + A P + P+ G PG PE+ +
Sbjct: 1076 AWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPG--PEDFGPE 1133
Query: 968 EPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHP---------TPPLQTDCTRQSSPQE- 1017
E + E G + + G GT G LP P P D R+ P
Sbjct: 1134 ENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHE 1193
Query: 1018 --RETVGPE------------LKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDL 1063
R+T P+ +SSS + D K PW + GP G
Sbjct: 1194 HFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPW-----HDGP---GTSEHR 1245
Query: 1064 STVADRGALSENGVIGEASPCGSEGKGLGSSGSEKLLCPRGRT 1106
A G + G GKG G G + + GR+
Sbjct: 1246 EMEAPGGPSEDRG-----------GKGRGGPGPAQRVPKSGRS 1277
Score = 40.8 bits (94), Expect = 0.010
Identities = 55/204 (26%), Positives = 75/204 (36%), Gaps = 16/204 (7%)
Query: 1285 VAAKVPNDGQNPGPEEEKLDESME-RPESPKEFLDLDNHNAATKRQSSLS--ASEYLYGT 1341
V PN+ N E+ KL+E + + E +E L N Q + A + +
Sbjct: 513 VPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQI 572
Query: 1342 PPPLSSGMGF-GSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQP 1400
PP SSG G FP M Q + P+ PP G +P
Sbjct: 573 QPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMG----PPGPQGQFRP 628
Query: 1401 NG-LSQEGPIYRCQEEGLGHFQAVMMEQ--IGTRSGIRGPFQEMYRPSGMQMHPVQSQAS 1457
G Q GP +G G Q M Q G G+ P Q+M+ P GMQ HP
Sbjct: 629 PGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRP-QDMHGPQGMQRHPGPHGPL 687
Query: 1458 FPKTPT----AATSQEEVPPHKPP 1477
P+ P ++ Q + P PP
Sbjct: 688 GPQGPPGPQGSSGPQGHMGPQGPP 711
Score = 38.1 bits (87), Expect = 0.064
Identities = 80/343 (23%), Positives = 106/343 (30%), Gaps = 77/343 (22%)
Query: 1159 LQGVGPVMGGKSPASHPQHFP--------PRGFQSNHPHSGGFP---RYRPPQGMRYSYH 1207
++ + P +P PQ FP P+GFQ HP S P P G + +
Sbjct: 569 VEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHP-SQQMPMNMAQMGPPGPQGQFR 627
Query: 1208 PPPQPSYHHYQRTPYY---ACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMA 1264
PP Q P + PQ F + PQG P GPP P P D +
Sbjct: 628 PPGPQGQMGPQGPPLHQGGGGPQGF------MGPQG-PQGPPQGLPRP-----QDMHGPQ 675
Query: 1265 SLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNA 1324
+Q P + + P PGP+ + P+ P
Sbjct: 676 GMQ---------RHPGPHGPLGPQGP-----PGPQGSSGPQGHMGPQGP------PGPQG 715
Query: 1325 ATKRQSSLSASEYLYGTPPPLSSGM----GFGSSAFPPHSVMLQTGPPY------TPQRP 1374
Q +L PP + GM G PPH +Q GP Q P
Sbjct: 716 HIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGP 775
Query: 1375 ASHFQPRAYSSP--------------VAALPPHH-PGATQPNGLSQEGPIYRCQEEGLGH 1419
PR P + PP G P GL GP +E G
Sbjct: 776 LMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGP-----QEMRGP 830
Query: 1420 FQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQASFPKTP 1462
+ M+ + + GP QE+ P G Q Q S P
Sbjct: 831 QEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPP 873
Score = 35.8 bits (81), Expect = 0.32
Identities = 80/327 (24%), Positives = 102/327 (31%), Gaps = 69/327 (21%)
Query: 1126 PGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFP------ 1179
PG G Q PPL+ G G QG MG + P PQ P
Sbjct: 629 PGPQGQMGPQGPPLHQGG-------------GGPQGF---MGPQGPQGPPQGLPRPQDMH 672
Query: 1180 -PRGFQSNHPHSGGFPRYRPPQGMRYSYHP--------PPQPSYHHYQRTPYYACPQSFS 1230
P+G Q HP G + P G + S P PP P H PQ
Sbjct: 673 GPQGMQ-RHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGH--------IGPQGPP 723
Query: 1231 DWQRPLHPQGSP-----SGPPASQ----PPPPRSLFSDKNAMASLQGCETLNAAL-TSPT 1280
Q L PQG P GPP + PP P + + +QG + + +P
Sbjct: 724 GPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQ-GIQGPVSQGPLMGLNPR 782
Query: 1281 RMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYG 1340
M P + Q P P+ + + P L H R + + G
Sbjct: 783 GMQGPPG--PRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMR-----GPQEIRG 835
Query: 1341 T--PPPLSSGMGFGSSAFPPHSVMLQTGPPY----TPQRPASHFQPRAYSSPVAALPPHH 1394
PPP S +G P Q GPP P + P A PH
Sbjct: 836 MQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHP 895
Query: 1395 -----PGATQPNGLSQEGPIYRCQEEG 1416
P Q L +GP +EG
Sbjct: 896 SQGPIPFQQQKTPLLGDGPRAPFNQEG 922
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,916,801
Number of Sequences: 37866
Number of extensions: 5171658
Number of successful extensions: 34546
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 1239
Number of HSP's that attempted gapping in prelim test: 22714
Number of HSP's gapped (non-prelim): 8946
length of query: 1484
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1369
effective length of database: 13,892,928
effective search space: 19019418432
effective search space used: 19019418432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.