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Search of human proteins with 148612870
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148612870 chromodomain helicase DNA binding protein 1-like
[Homo sapiens]
(897 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148612870 chromodomain helicase DNA binding protein 1-like [H... 1777 0.0
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r... 438 e-123
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re... 432 e-121
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re... 429 e-120
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 410 e-114
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 410 e-114
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 410 e-114
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 410 e-114
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 410 e-114
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 408 e-113
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 405 e-112
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 380 e-105
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 378 e-104
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 368 e-101
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 363 e-100
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 358 1e-98
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 358 2e-98
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 357 3e-98
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 357 4e-98
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 353 4e-97
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 353 4e-97
gi|21914927 helicase, lymphoid-specific [Homo sapiens] 350 3e-96
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 350 4e-96
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 347 2e-95
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 347 2e-95
gi|190358536 SWI/SNF-related, matrix-associated actin-dependent ... 262 9e-70
gi|190358532 SWI/SNF-related, matrix-associated actin-dependent ... 262 9e-70
gi|190358534 SWI/SNF-related, matrix-associated actin-dependent ... 262 1e-69
gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto... 236 7e-62
gi|4557565 excision repair cross-complementing rodent repair def... 229 9e-60
>gi|148612870 chromodomain helicase DNA binding protein 1-like [Homo
sapiens]
Length = 897
Score = 1777 bits (4602), Expect = 0.0
Identities = 897/897 (100%), Positives = 897/897 (100%)
Query: 1 MERAGATSRGGQAPGFLLRLHTEGRAEAARVQEQDLRQWGLTGIHLRSYQLEGVNWLAQR 60
MERAGATSRGGQAPGFLLRLHTEGRAEAARVQEQDLRQWGLTGIHLRSYQLEGVNWLAQR
Sbjct: 1 MERAGATSRGGQAPGFLLRLHTEGRAEAARVQEQDLRQWGLTGIHLRSYQLEGVNWLAQR 60
Query: 61 FHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLSVLSNWKEEMQRFAPG 120
FHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLSVLSNWKEEMQRFAPG
Sbjct: 61 FHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLSVLSNWKEEMQRFAPG 120
Query: 121 LSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLK 180
LSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLK
Sbjct: 121 LSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLK 180
Query: 181 NQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDI 240
NQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDI
Sbjct: 181 NQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDI 240
Query: 241 EKESESASELHKLLQPFLLRRVKAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDA 300
EKESESASELHKLLQPFLLRRVKAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDA
Sbjct: 241 EKESESASELHKLLQPFLLRRVKAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDA 300
Query: 301 FENETAKKVKLQNILSQLRKCVDHPYLFDGVEPEPFEVGDHLTEASGKLHLLDKLLAFLY 360
FENETAKKVKLQNILSQLRKCVDHPYLFDGVEPEPFEVGDHLTEASGKLHLLDKLLAFLY
Sbjct: 301 FENETAKKVKLQNILSQLRKCVDHPYLFDGVEPEPFEVGDHLTEASGKLHLLDKLLAFLY 360
Query: 361 SGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPIFVFLLS 420
SGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPIFVFLLS
Sbjct: 361 SGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPIFVFLLS 420
Query: 421 TRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVY 480
TRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVY
Sbjct: 421 TRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVY 480
Query: 481 RKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLES 540
RKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLES
Sbjct: 481 RKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLES 540
Query: 541 ILGETKDGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQK 600
ILGETKDGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQK
Sbjct: 541 ILGETKDGQWVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQK 600
Query: 601 TLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEE 660
TLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEE
Sbjct: 601 TLLEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEE 660
Query: 661 KKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYV 720
KKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYV
Sbjct: 661 KKRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYV 720
Query: 721 SGDVTHPQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGV 780
SGDVTHPQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGV
Sbjct: 721 SGDVTHPQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGV 780
Query: 781 LLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIKMAALEEGLKKIFLAAKKKKASVHL 840
LLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIKMAALEEGLKKIFLAAKKKKASVHL
Sbjct: 781 LLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIKMAALEEGLKKIFLAAKKKKASVHL 840
Query: 841 PRIGHATKGFNWYGTERLIRKHLAARGIPTYIYYFPRSKSAVLHAQSSSSSSRQLVP 897
PRIGHATKGFNWYGTERLIRKHLAARGIPTYIYYFPRSKSAVLHAQSSSSSSRQLVP
Sbjct: 841 PRIGHATKGFNWYGTERLIRKHLAARGIPTYIYYFPRSKSAVLHAQSSSSSSRQLVP 897
>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform b [Homo sapiens]
Length = 1042
Score = 438 bits (1127), Expect = e-123
Identities = 265/691 (38%), Positives = 394/691 (57%), Gaps = 40/691 (5%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
LR YQ+ G+NWL + IL DEMGLGKT QTIAL YL N GP ++L P S
Sbjct: 183 LRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKS 242
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
L NW E +R+ P L + + GDK+ RA +D + V +T+YE+ +K+ S K
Sbjct: 243 TLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKK 302
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLF 225
F W LV+DEAHR+KN+ S L + + EF LLLTGTP+QN+L EL++LL+F+ PD+F
Sbjct: 303 FHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVF 362
Query: 226 SKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPKKTEVVIYHGMSAL 285
+ + D ++ + + LH +L+PFLLRR+K +V LP K E+ IY G+S +
Sbjct: 363 NSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKM 422
Query: 286 QKKYYKAILMKDLDAFENETAK--KVKLQNILSQLRKCVDHPYLFDGVEP-EPFEVGDHL 342
Q+++Y ILMKD+D N + K K++L NIL QLRKC +HPYLFDG EP P+ +H+
Sbjct: 423 QREWYTKILMKDIDVL-NSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHI 481
Query: 343 TEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEER 402
SGK+ +LDKLLA L G RVL+FSQMT++LDIL+DY +RGY Y R+DG EER
Sbjct: 482 VSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEER 541
Query: 403 HLAIKNFG--QQPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQ 460
AI+ F F+F+LSTRAGG+G+NL +AD VI DSD+NPQ DLQA RAHRIGQ
Sbjct: 542 EEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQ 601
Query: 461 NKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKF 520
K V+V RLI +TVEE + +A KL+L +++I+ G L Q+ A ++ ++++
Sbjct: 602 KKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNKLAKEEMLQMIRH 659
Query: 521 GLDKLLASEGSTMDEIDLESIL--GETKDGQWVSDALPAAEGGSRD-QEEGKNHMYLFEG 577
G + AS+ S + + D+ +IL GE K + E R+ + + + +Y FEG
Sbjct: 660 GATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRMDIEQSLYKFEG 719
Query: 578 KDYSK----------EPSKEDRKS-------FEQLVNLQKTLLEKASQEGRSLRNKGSVL 620
+DY + EP K +RK+ F + + + + + KA + + +
Sbjct: 720 EDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRPPKQPNVQDFQF 779
Query: 621 IPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEEKKR-------QKEEAEHKKK 673
P + +++ + + + + + + EE+K+ EE E K+K
Sbjct: 780 FPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEPLTPEETEEKEK 839
Query: 674 MAW-----WESNNYQSFCLPSEESEPEDLEN 699
+ W ++ F +E+ +D++N
Sbjct: 840 LLTQGFTNWTKRDFNQFIKANEKYGRDDIDN 870
>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform a [Homo sapiens]
Length = 1054
Score = 432 bits (1112), Expect = e-121
Identities = 265/703 (37%), Positives = 396/703 (56%), Gaps = 52/703 (7%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
LR YQ+ G+NWL + IL DEMGLGKT QTIAL YL N GP ++L P S
Sbjct: 183 LRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKS 242
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
L NW E +R+ P L + + GDK+ RA +D + V +T+YE+ +K+ S K
Sbjct: 243 TLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKK 302
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLF 225
F W LV+DEAHR+KN+ S L + + EF LLLTGTP+QN+L EL++LL+F+ PD+F
Sbjct: 303 FHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVF 362
Query: 226 SKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPKKTEVVIYHGMSAL 285
+ + D ++ + + LH +L+PFLLRR+K +V LP K E+ IY G+S +
Sbjct: 363 NSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKM 422
Query: 286 QKKYYKAILMKDLDAFENETAK--KVKLQNILSQLRKCVDHPYLFDGVEP-EPFEVGDHL 342
Q+++Y ILMKD+D N + K K++L NIL QLRKC +HPYLFDG EP P+ +H+
Sbjct: 423 QREWYTKILMKDIDVL-NSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHI 481
Query: 343 TEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEER 402
SGK+ +LDKLLA L G RVL+FSQMT++LDIL+DY +RGY Y R+DG EER
Sbjct: 482 VSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEER 541
Query: 403 H---LAIKNFGQQPI-----------FVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQND 448
L ++ GQ+ F+F+LSTRAGG+G+NL +AD VI DSD+NPQ D
Sbjct: 542 EDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVD 601
Query: 449 LQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAA 508
LQA RAHRIGQ K V+V RLI +TVEE + +A KL+L +++I+ G L Q+
Sbjct: 602 LQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNK 659
Query: 509 DADLQLSEILKFGLDKLLASEGSTMDEIDLESIL--GETKDGQWVSDALPAAEGGSRD-Q 565
A ++ ++++ G + AS+ S + + D+ +IL GE K + E R+ +
Sbjct: 660 LAKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFR 719
Query: 566 EEGKNHMYLFEGKDYSK----------EPSKEDRKS-------FEQLVNLQKTLLEKASQ 608
+ + +Y FEG+DY + EP K +RK+ F + + + + + KA +
Sbjct: 720 MDIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPR 779
Query: 609 EGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEEKKR----- 663
+ + P + +++ + + + + + + EE+K+
Sbjct: 780 PPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAE 839
Query: 664 --QKEEAEHKKKMAW-----WESNNYQSFCLPSEESEPEDLEN 699
EE E K+K+ W ++ F +E+ +D++N
Sbjct: 840 PLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDN 882
>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a5 [Homo sapiens]
Length = 1052
Score = 429 bits (1104), Expect = e-120
Identities = 271/703 (38%), Positives = 390/703 (55%), Gaps = 52/703 (7%)
Query: 38 QWGLTGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGP 97
+WG LR YQ+ G+NWL + IL DEMGLGKT QTI+L Y+ N GP
Sbjct: 176 KWG----KLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGP 231
Query: 98 FLILCPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICL 157
++L P S L NW E +R+ P L V GDKE+RA +D+ + V +T+YE+ +
Sbjct: 232 HMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLI 291
Query: 158 KDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLL 217
K+ S K F W LV+DEAHR+KN+ S L + + EF LLLTGTP+QN+L EL+SLL
Sbjct: 292 KEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLL 351
Query: 218 SFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPKKTEVV 277
+F+ PD+F+ + D + + + LH +L+PFLLRR+KA+V LP K EV
Sbjct: 352 NFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPFLLRRIKADVEKSLPPKKEVK 411
Query: 278 IYHGMSALQKKYYKAILMKDLDAFENETAK--KVKLQNILSQLRKCVDHPYLFDGVEP-E 334
IY G+S +Q+++Y ILMKD+D N K K++L NIL QLRKC +HPYLFDG EP
Sbjct: 412 IYVGLSKMQREWYTRILMKDIDIL-NSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGP 470
Query: 335 PFEVGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVD 394
P+ HL SGK+ +LDKLL L G RVL+FSQMT++LDIL+DY +R Y Y R+D
Sbjct: 471 PYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLD 530
Query: 395 GSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAA 452
G +ER +I + + FVF+LSTRAGG+G+NL AD VI DSD+NPQ DLQA
Sbjct: 531 GQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAM 590
Query: 453 ARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFT-LGAQKPAADAD 511
RAHRIGQ K+V+V R I +TVEE + +A KL+L +++I+ G K D
Sbjct: 591 DRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEM 650
Query: 512 LQLSEILKFGLDKLLASEGSTMDEIDLESIL--GETKDGQWVSDALPAAEGGSRD-QEEG 568
LQ+ ++ G + AS+ S + + D++ IL G K + E R+ +
Sbjct: 651 LQM---IRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT 707
Query: 569 KNHMYLFEGKDYSK----------EPSKEDRKS-------FEQLVNLQKTLLEKASQEGR 611
++ +Y FEG+DY + EP K +RK+ F + + + + KA + +
Sbjct: 708 ESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPK 767
Query: 612 SLRNKGSVLIPG----------LVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEEK 661
+ P L T +V EL + + ++E ++ ++ E +
Sbjct: 768 QPNVQDFQFFPPRLFELLEKEILFYRKTIGYKVPRNPELPNAAQAQKE---EQLKIDEAE 824
Query: 662 KRQKEEAEHKKKMAW-----WESNNYQSFCLPSEESEPEDLEN 699
EE E K+K+ W ++ F +E+ +D+EN
Sbjct: 825 SLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIEN 867
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 410 bits (1055), Expect = e-114
Identities = 269/707 (38%), Positives = 389/707 (55%), Gaps = 55/707 (7%)
Query: 40 GLTGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFL 99
G G+ LR YQL G+NWLA + N CIL DEMGLGKT QTI+ YL GPFL
Sbjct: 475 GHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFL 534
Query: 100 ILCPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQ-----QDLKQESRFHVLLTTYE 154
++ PLS L++W+ E+Q +A ++ V Y GD R ++ + +F++LLTTYE
Sbjct: 535 LVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYE 594
Query: 155 ICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELY 214
I LKD +FL W+ + VDEAHRLKN SLL+KTL +F LL+TGTP+QNSL+EL+
Sbjct: 595 ILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELW 654
Query: 215 SLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASE-----LHKLLQPFLLRRVKAEVATE 269
SLL F+ P+ FS ++D E+E E LHK L+PFLLRRVK +V
Sbjct: 655 SLLHFIMPEKFSS---------WEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKS 705
Query: 270 LPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVK-LQNILSQLRKCVDHPYLF 328
LP K E ++ MSALQK+YYK IL ++ A + NI+ +L+KC +H YL
Sbjct: 706 LPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLI 765
Query: 329 DGVEPEPF----EVGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMD 384
+ F E HL +SGKL LLDKLL L G+RVL+FSQM +MLDIL +Y+
Sbjct: 766 KPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLK 825
Query: 385 YRGYSYERVDGSVRGEERHLAIKNFGQQ--PIFVFLLSTRAGGVGMNLTAADTVIFVDSD 442
YR + ++R+DGS++GE R A+ +F + F FLLSTRAGG+G+NL +ADTV+ DSD
Sbjct: 826 YRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSD 885
Query: 443 FNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIE-----GG 497
+NPQNDLQA ARAHRIGQ K V + RL+ + +VEE + +A K+ L +++I+ G
Sbjct: 886 WNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGK 945
Query: 498 HFTLGAQKPAADADL---QLSEILKFGLDKLLAS-EGSTMD--EIDLESILGETKDGQWV 551
P++ +LS ILKFG ++L EG + E+D++ IL + +
Sbjct: 946 TVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHE-- 1003
Query: 552 SDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGR 611
++ P G + + + D EP + + E + Q+ LE+ ++
Sbjct: 1004 NEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKE 1063
Query: 612 --------SLRNKGSVLIPGLVEGSTKRKRVLSPEELED-RQKKRQEAAAKRRRLIEEKK 662
+RN + EG R R S + + + KR + + R + E
Sbjct: 1064 LEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENI 1123
Query: 663 RQKEEAEHKKKMAWWESNNYQSFCLPSE--ESEPEDLENGEESSAEL 707
+ +AE ++ + +Y+ F P E ++ D E ++S +L
Sbjct: 1124 KGFSDAEIRRFI-----KSYKKFGGPLERLDAIARDAELVDKSETDL 1165
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 410 bits (1054), Expect = e-114
Identities = 239/568 (42%), Positives = 342/568 (60%), Gaps = 47/568 (8%)
Query: 35 DLRQWGL--TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRL 92
D + W + TG L YQLEG+NWL + IL DEMGLGKT QTI L
Sbjct: 687 DKQPWYIDSTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSLYKEG 746
Query: 93 NDEGPFLILCPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD------------- 139
+ +GP+L+ PLS + NW+ E + +AP VTY GDKE R+ ++++
Sbjct: 747 HSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFEDNAIRSGK 806
Query: 140 ----LKQES--RFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEF 193
+K+E +FHVLLT+YE+ D + L S W+ LVVDEAHRLKN S + L+ +
Sbjct: 807 KVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFRVLNSY 866
Query: 194 SVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKL 253
+ + LLLTGTP+QN+L+EL+ LL+F+ P+ F+ E F++ + DI KE + +LH L
Sbjct: 867 KIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLE--GFLEEFADISKEDQ-IKKLHDL 923
Query: 254 LQPFLLRRVKAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETA-KKVKLQ 312
L P +LRR+KA+V +P KTE+++ +S +QKKYYK IL ++ +A ++ +V L
Sbjct: 924 LGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGGNQVSLL 983
Query: 313 NILSQLRKCVDHPYLFD------GVEPEPFEVGDHLTEASGKLHLLDKLLAFLYSGGHRV 366
NI+ L+KC +HPYLF V P G L ++SGKL LL K+L L GHRV
Sbjct: 984 NIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGSSLVKSSGKLMLLQKMLKKLRDEGHRV 1043
Query: 367 LLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERHLAIKNF---GQQPIFVFLLSTRA 423
L+FSQMT+MLD+L+D+++Y GY YER+DG + G R AI F G Q F FLLSTRA
Sbjct: 1044 LIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQ-FCFLLSTRA 1102
Query: 424 GGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKA 483
GG+G+NL ADTVI DSD+NP ND+QA +RAHRIGQNK V + R + R +VEE + + A
Sbjct: 1103 GGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVA 1162
Query: 484 ASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILG 543
K+ LT++++ G LG+ K + +L +ILKFG ++L D+E ++
Sbjct: 1163 KRKMMLTHLVVRPG---LGS-KSGSMTKQELDDILKFGTEELFKD--------DVEGMMS 1210
Query: 544 ETKDGQWVSDALPAAEGGSRDQEEGKNH 571
+ + + +++GG+ K H
Sbjct: 1211 QGQRPVTPIPDVQSSKGGNLAASAKKKH 1238
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 410 bits (1053), Expect = e-114
Identities = 257/667 (38%), Positives = 376/667 (56%), Gaps = 47/667 (7%)
Query: 42 TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLIL 101
TG L YQLEG+NWL + IL DEMGLGKT QTI L + +GPFL+
Sbjct: 732 TGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVS 791
Query: 102 CPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD-----------------LKQES 144
PLS + NW+ E Q +AP VTY GDK+ RA ++++ +K+E+
Sbjct: 792 APLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREA 851
Query: 145 --RFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLT 202
+FHVLLT+YE+ D + L S W+ LVVDEAHRLKN S + L+ + + LLLT
Sbjct: 852 QVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLT 911
Query: 203 GTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRV 262
GTP+QN+L+EL+ LL+F+ P+ F+ E F++ + DI KE + +LH LL P +LRR+
Sbjct: 912 GTPLQNNLEELFHLLNFLTPERFNNLE--GFLEEFADISKEDQ-IKKLHDLLGPHMLRRL 968
Query: 263 KAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETA-KKVKLQNILSQLRKC 321
KA+V +P KTE+++ +S +QKKYYK IL ++ +A + +V L NI+ L+KC
Sbjct: 969 KADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLKKC 1028
Query: 322 VDHPYLFDGVEPEPFEV------GDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQM 375
+HPYLF E ++ G L ++SGKL LL K+L L GHRVL+FSQMT+M
Sbjct: 1029 CNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKM 1088
Query: 376 LDILQDYMDYRGYSYERVDGSVRGEERHLAIKNF---GQQPIFVFLLSTRAGGVGMNLTA 432
LD+L+D++DY GY YER+DG + G R AI F G Q F FLLSTRAGG+G+NL
Sbjct: 1089 LDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQ-FCFLLSTRAGGLGINLAT 1147
Query: 433 ADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNM 492
ADTVI DSD+NP ND+QA +RAHRIGQ V + R + R +VEE + + A K+ LT++
Sbjct: 1148 ADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHL 1207
Query: 493 IIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETKDGQWVS 552
++ G LG+ K + + +L +ILKFG ++L E ++ + S++ D + ++
Sbjct: 1208 VVRPG---LGS-KAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVI--HYDNEAIA 1261
Query: 553 DALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKED------RKSFEQLVNLQKTLLEKA 606
L + + D + + YL K +ED R+ +Q N+ EK
Sbjct: 1262 RLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKL 1321
Query: 607 SQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEEKKRQKE 666
+ + + L L +G RK+V + ++ Q + E + E+ + E
Sbjct: 1322 LRHHYEQQQED--LARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPE 1379
Query: 667 EAEHKKK 673
K+
Sbjct: 1380 GRRQSKR 1386
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 410 bits (1053), Expect = e-114
Identities = 257/667 (38%), Positives = 376/667 (56%), Gaps = 47/667 (7%)
Query: 42 TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLIL 101
TG L YQLEG+NWL + IL DEMGLGKT QTI L + +GPFL+
Sbjct: 732 TGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVS 791
Query: 102 CPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD-----------------LKQES 144
PLS + NW+ E Q +AP VTY GDK+ RA ++++ +K+E+
Sbjct: 792 APLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREA 851
Query: 145 --RFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLT 202
+FHVLLT+YE+ D + L S W+ LVVDEAHRLKN S + L+ + + LLLT
Sbjct: 852 QVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLT 911
Query: 203 GTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRV 262
GTP+QN+L+EL+ LL+F+ P+ F+ E F++ + DI KE + +LH LL P +LRR+
Sbjct: 912 GTPLQNNLEELFHLLNFLTPERFNNLE--GFLEEFADISKEDQ-IKKLHDLLGPHMLRRL 968
Query: 263 KAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETA-KKVKLQNILSQLRKC 321
KA+V +P KTE+++ +S +QKKYYK IL ++ +A + +V L NI+ L+KC
Sbjct: 969 KADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLKKC 1028
Query: 322 VDHPYLFDGVEPEPFEV------GDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQM 375
+HPYLF E ++ G L ++SGKL LL K+L L GHRVL+FSQMT+M
Sbjct: 1029 CNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKM 1088
Query: 376 LDILQDYMDYRGYSYERVDGSVRGEERHLAIKNF---GQQPIFVFLLSTRAGGVGMNLTA 432
LD+L+D++DY GY YER+DG + G R AI F G Q F FLLSTRAGG+G+NL
Sbjct: 1089 LDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQ-FCFLLSTRAGGLGINLAT 1147
Query: 433 ADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNM 492
ADTVI DSD+NP ND+QA +RAHRIGQ V + R + R +VEE + + A K+ LT++
Sbjct: 1148 ADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHL 1207
Query: 493 IIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETKDGQWVS 552
++ G LG+ K + + +L +ILKFG ++L E ++ + S++ D + ++
Sbjct: 1208 VVRPG---LGS-KAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVI--HYDNEAIA 1261
Query: 553 DALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKED------RKSFEQLVNLQKTLLEKA 606
L + + D + + YL K +ED R+ +Q N+ EK
Sbjct: 1262 RLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKL 1321
Query: 607 SQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEEKKRQKE 666
+ + + L L +G RK+V + ++ Q + E + E+ + E
Sbjct: 1322 LRHHYEQQQED--LARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPE 1379
Query: 667 EAEHKKK 673
K+
Sbjct: 1380 GRRQSKR 1386
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 410 bits (1053), Expect = e-114
Identities = 257/667 (38%), Positives = 376/667 (56%), Gaps = 47/667 (7%)
Query: 42 TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLIL 101
TG L YQLEG+NWL + IL DEMGLGKT QTI L + +GPFL+
Sbjct: 791 TGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVS 850
Query: 102 CPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD-----------------LKQES 144
PLS + NW+ E Q +AP VTY GDK+ RA ++++ +K+E+
Sbjct: 851 APLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREA 910
Query: 145 --RFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLT 202
+FHVLLT+YE+ D + L S W+ LVVDEAHRLKN S + L+ + + LLLT
Sbjct: 911 QVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLT 970
Query: 203 GTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRV 262
GTP+QN+L+EL+ LL+F+ P+ F+ E F++ + DI KE + +LH LL P +LRR+
Sbjct: 971 GTPLQNNLEELFHLLNFLTPERFNNLE--GFLEEFADISKEDQ-IKKLHDLLGPHMLRRL 1027
Query: 263 KAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETA-KKVKLQNILSQLRKC 321
KA+V +P KTE+++ +S +QKKYYK IL ++ +A + +V L NI+ L+KC
Sbjct: 1028 KADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLKKC 1087
Query: 322 VDHPYLFDGVEPEPFEV------GDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQM 375
+HPYLF E ++ G L ++SGKL LL K+L L GHRVL+FSQMT+M
Sbjct: 1088 CNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKM 1147
Query: 376 LDILQDYMDYRGYSYERVDGSVRGEERHLAIKNF---GQQPIFVFLLSTRAGGVGMNLTA 432
LD+L+D++DY GY YER+DG + G R AI F G Q F FLLSTRAGG+G+NL
Sbjct: 1148 LDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQ-FCFLLSTRAGGLGINLAT 1206
Query: 433 ADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNM 492
ADTVI DSD+NP ND+QA +RAHRIGQ V + R + R +VEE + + A K+ LT++
Sbjct: 1207 ADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHL 1266
Query: 493 IIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETKDGQWVS 552
++ G LG+ K + + +L +ILKFG ++L E ++ + S++ D + ++
Sbjct: 1267 VVRPG---LGS-KAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVI--HYDNEAIA 1320
Query: 553 DALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKED------RKSFEQLVNLQKTLLEKA 606
L + + D + + YL K +ED R+ +Q N+ EK
Sbjct: 1321 RLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKL 1380
Query: 607 SQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEEKKRQKE 666
+ + + L L +G RK+V + ++ Q + E + E+ + E
Sbjct: 1381 LRHHYEQQQED--LARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPE 1438
Query: 667 EAEHKKK 673
K+
Sbjct: 1439 GRRQSKR 1445
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 408 bits (1049), Expect = e-113
Identities = 229/519 (44%), Positives = 324/519 (62%), Gaps = 37/519 (7%)
Query: 42 TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLIL 101
TG L YQ+EG+NWL + IL DEMGLGKT QT L + +GPFL+
Sbjct: 722 TGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVS 781
Query: 102 CPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD-----------------LKQES 144
PLS + NW+ E + +AP + VTY GDK+ RA ++++ +K+E+
Sbjct: 782 APLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEA 841
Query: 145 --RFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLT 202
+FHVLLT+YE+ D + L S W+ L+VDEAHRLKN S + L+ +S+ LLLT
Sbjct: 842 SVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLLT 901
Query: 203 GTPIQNSLQELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRV 262
GTP+QN+L+EL+ LL+F+ P+ F E F++ + DI KE + +LH +L P +LRR+
Sbjct: 902 GTPLQNNLEELFHLLNFLTPERFHNLE--GFLEEFADIAKEDQ-IKKLHDMLGPHMLRRL 958
Query: 263 KAEVATELPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETA-KKVKLQNILSQLRKC 321
KA+V +P KTE+++ +S +QKKYYK IL ++ +A +V L N++ L+KC
Sbjct: 959 KADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKC 1018
Query: 322 VDHPYLFDGVEPEPFEV------GDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQM 375
+HPYLF E ++ G L ASGKL LL K+L L GGHRVL+FSQMT+M
Sbjct: 1019 CNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKM 1078
Query: 376 LDILQDYMDYRGYSYERVDGSVRGEERHLAIKNF---GQQPIFVFLLSTRAGGVGMNLTA 432
LD+L+D++++ GY YER+DG + G R AI F G Q F FLLSTRAGG+G+NL
Sbjct: 1079 LDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQ-FCFLLSTRAGGLGINLAT 1137
Query: 433 ADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNM 492
ADTVI DSD+NP ND+QA +RAHRIGQNK V + R + R +VEE + + A K+ LT++
Sbjct: 1138 ADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHL 1197
Query: 493 IIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLASEGS 531
++ G LG+ K + + +L +ILKFG ++L E +
Sbjct: 1198 VVRPG---LGS-KTGSMSKQELDDILKFGTEELFKDEAT 1232
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 405 bits (1040), Expect = e-112
Identities = 258/657 (39%), Positives = 375/657 (57%), Gaps = 50/657 (7%)
Query: 40 GLTGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFL 99
G + LR YQLEG+NWLA + N IL DEMGLGKT QTI+ YL + GPFL
Sbjct: 478 GGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFL 537
Query: 100 ILCPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQ-----DLKQESRFHVLLTTYE 154
I+ PLS L++W+ E + +AP ++ V Y GD R +++ + +F+ L+TTYE
Sbjct: 538 IVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYE 597
Query: 155 ICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELY 214
I LKD + L S W+ L VDEAHRLKN SLL+KTL +F LL+TGTP+QNSL+EL+
Sbjct: 598 ILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELW 657
Query: 215 SLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASE-----LHKLLQPFLLRRVKAEVATE 269
SLL F+ P+ F + ++D E++ E LHK+L+PFLLRRVK +V
Sbjct: 658 SLLHFIMPEKF---------EFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKS 708
Query: 270 LPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVK-LQNILSQLRKCVDHPYLF 328
LP K E ++ MSALQK+YYK IL ++ A T NI+ +L+KC +H YL
Sbjct: 709 LPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLI 768
Query: 329 DGVEPEPFEVGDH----LTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMD 384
E E G L +SGKL LLDKLL L G+RVL+FSQM +MLDIL +Y+
Sbjct: 769 KPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLT 828
Query: 385 YRGYSYERVDGSVRGEERHLAIKNFGQQPI--FVFLLSTRAGGVGMNLTAADTVIFVDSD 442
+ Y ++R+DGS++GE R A+ +F F FLLSTRAGG+G+NL +ADTV+ DSD
Sbjct: 829 IKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSD 888
Query: 443 FNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIE----GGH 498
+NPQNDLQA ARAHRIGQ K V + RL+ + TVEE + +A K+ L +++I+ G
Sbjct: 889 WNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGR 948
Query: 499 FTLGAQKPAADAD----LQLSEILKFGLDKL---LASEGSTMDEIDLESI--LGETKDGQ 549
L ++++ +L+ ILKFG + L L E S E+D++ I L ET++ +
Sbjct: 949 TILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENE 1008
Query: 550 WVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQE 609
+ A D+ + + F + +E + K +++++ ++ +K +E
Sbjct: 1009 VSTSA--------TDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQR--KKVEEE 1058
Query: 610 GRSLRNKGSVLIPGLVEGSTKRKRVLSPEELED-RQKKRQEAAAKRRRLIEEKKRQK 665
R + ++P + + K + S + E RQ +R A+ ++ K+ K
Sbjct: 1059 ERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPK 1115
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 380 bits (975), Expect = e-105
Identities = 229/535 (42%), Positives = 318/535 (59%), Gaps = 49/535 (9%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALF--IYLAGRLNDEGPFLILCP 103
LR YQLEGVNWL ++ CIL DEMGLGKT Q+I IYL G GPFL++ P
Sbjct: 968 LREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGI---HGPFLVIAP 1024
Query: 104 LSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQ-----------QDLKQESRFHVLLTT 152
LS + NW+ E + + L+ V Y G + R +Q + +K +FH ++TT
Sbjct: 1025 LSTIPNWEREFRTWTE-LNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITT 1083
Query: 153 YEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQE 212
+E+ L D L++ PW +V+DEAHRLKN++ L + L + +LLTGTP+QN+++E
Sbjct: 1084 FEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEE 1143
Query: 213 LYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPK 272
L+SLL F+EP F E F+Q + D++ E E +L +L+P +LRR+K +V L
Sbjct: 1144 LFSLLHFLEPSRFPSETT--FMQEFGDLKTE-EQVQKLQAILKPMMLRRLKEDVEKNLAP 1200
Query: 273 KTEVVIYHGMSALQKKYYKAILMKDLDAFENE--TAKKVKLQNILSQLRKCVDHPYLFDG 330
K E +I ++ +QKKYY+AIL K+ A L N + +LRKC +HPYL +G
Sbjct: 1201 KEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVPNLLNTMMELRKCCNHPYLING 1260
Query: 331 VEPEPFEVGDH-------------LTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLD 377
E + E + +A+GKL L+DKLL L +GGHRVL+FSQM + LD
Sbjct: 1261 AEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLD 1320
Query: 378 ILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPI--FVFLLSTRAGGVGMNLTAADT 435
IL+DY+ R Y YER+DG VRG R AI F + FVFLL TRAGG+G+NLTAADT
Sbjct: 1321 ILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADT 1380
Query: 436 VIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIE 495
I DSD+NPQNDLQA AR HRIGQ+KSVK+ RLI R++ E ++ KA+ KL L +++
Sbjct: 1381 CIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQ 1440
Query: 496 GGHFTLGAQKPAADADLQLS-----EILKFGLDKLL---ASEGSTMDEIDLESIL 542
++ ++ A + QLS ++L+ G L EGS E D++ IL
Sbjct: 1441 ----SMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQIL 1491
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 378 bits (971), Expect = e-104
Identities = 224/531 (42%), Positives = 325/531 (61%), Gaps = 42/531 (7%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALF--IYLAGRLNDEGPFLILCP 103
LR YQLEG+NWL ++ + CIL DEMGLGKT Q+I I+L G GPFLI+ P
Sbjct: 461 LREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLSEIFLRGI---HGPFLIIAP 517
Query: 104 LSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQ-----------DLKQESRFHVLLTT 152
LS ++NW+ E + + ++ + Y G + R +QQ L +FHV++TT
Sbjct: 518 LSTITNWEREFRTWTE-MNAIVYHGSQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITT 576
Query: 153 YEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQE 212
+E+ L D LK WS +++DEAHRLKN++ L + L ++ +LLTGTP+QNS++E
Sbjct: 577 FEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEE 636
Query: 213 LYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPK 272
L+SLL+F+EP F E F++ + D++ E E +L +L+P +LRR+K +V L
Sbjct: 637 LFSLLNFLEPSQFPSETA--FLEEFGDLKTE-EQVKKLQSILKPMMLRRLKDDVEKNLAP 693
Query: 273 KTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILS---QLRKCVDHPYLFD 329
K E +I ++ +QKKYY+AIL K+ +F + A + + N+++ +LRKC +HPYL +
Sbjct: 694 KQETIIEVELTNIQKKYYRAILEKNF-SFLTKGANQHNMPNLINTMMELRKCCNHPYLIN 752
Query: 330 GVEPEPFEVG-------------DHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQML 376
G E + E + +A+GKL L+DKLL L +GGH+VL+FSQM + L
Sbjct: 753 GAEEKILEDFRKTHSPDAPDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCL 812
Query: 377 DILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPI--FVFLLSTRAGGVGMNLTAAD 434
DIL+DY+ R Y+YER+DG VRG R AI F + FVFLL TRAGG+G+NLTAAD
Sbjct: 813 DILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAAD 872
Query: 435 TVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMII 494
T I DSD+NPQNDLQA AR HRIGQ+K+VKV RLI R++ E ++ KA+ KL L ++
Sbjct: 873 TCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVL 932
Query: 495 EGGHFTLGAQKPAADADLQLSEILKFGLDKLL---ASEGSTMDEIDLESIL 542
+ + G + +++ ++L+ G L EGS E D++ IL
Sbjct: 933 QDINRKGGTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQIL 983
Score = 30.8 bits (68), Expect = 5.9
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 603 LEKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRLIEEKK 662
+E + G ++ K PG EG+ K + P+ ++KR+ K R +E K
Sbjct: 82 MEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKP----KRKREPKEPKEPRKAKEPK 137
Query: 663 RQKEEAEHKKK 673
+ KE E K+K
Sbjct: 138 KAKEHKEPKQK 148
>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
sapiens]
Length = 2302
Score = 368 bits (944), Expect = e-101
Identities = 221/535 (41%), Positives = 321/535 (60%), Gaps = 49/535 (9%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
LR YQLEGVNWL ++ + CIL DEMGLGKT Q+IA F+ + GPFL++ PLS
Sbjct: 532 LREYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIA-FLQEVYNVGIHGPFLVIAPLS 590
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD-----------LKQESRFHVLLTTYE 154
++NW+ E + ++ + Y G R +QQ + +F L+TT+E
Sbjct: 591 TITNWEREFNTWTE-MNTIVYHGSLASRQMIQQYEMYCKDSRGRLIPGAYKFDALITTFE 649
Query: 155 ICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELY 214
+ L D L+ W +++DEAHRLKN++ L +L + +LLTGTP+QN+++EL+
Sbjct: 650 MILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELF 709
Query: 215 SLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELPKKT 274
SLL F+EP F E +F++ + D++ E E +L +L+P +LRR+K +V L K
Sbjct: 710 SLLHFLEPSQFPSES--EFLKDFGDLKTE-EQVQKLQAILKPMMLRRLKEDVEKNLAPKQ 766
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILS---QLRKCVDHPYLFDGV 331
E +I ++ +QKKYY+AIL K+ +F ++ A + N+L+ +LRKC +HPYL +G
Sbjct: 767 ETIIEVELTNIQKKYYRAILEKNF-SFLSKGAGHTNMPNLLNTMMELRKCCNHPYLINGA 825
Query: 332 E--------------PEPFEVGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLD 377
E P F + + ++GKL L+DKLL L +GGH+VL+FSQM + LD
Sbjct: 826 EEKILTEFREACHIIPHDFHL-QAMVRSAGKLVLIDKLLPKLKAGGHKVLIFSQMVRCLD 884
Query: 378 ILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPI--FVFLLSTRAGGVGMNLTAADT 435
IL+DY+ R Y YER+DG VRG R AI F + FVFLL TRAGG+G+NLTAADT
Sbjct: 885 ILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADT 944
Query: 436 VIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIE 495
I DSD+NPQNDLQA AR HRIGQ+K+VKV RLI R++ E ++ KA+ KL L +++
Sbjct: 945 CIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQ 1004
Query: 496 G-----GHFTLGAQKPAADADLQLSEILKFGLDKLLA---SEGSTMDEIDLESIL 542
G+ T G Q+ + ++ ++L+ G + EGS E D++ IL
Sbjct: 1005 SMSGRDGNIT-GIQQ---FSKKEIEDLLRKGAYAAIMEEDDEGSKFCEEDIDQIL 1055
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 363 bits (933), Expect = e-100
Identities = 218/535 (40%), Positives = 324/535 (60%), Gaps = 43/535 (8%)
Query: 43 GIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILC 102
G LR YQLEG+NWL ++ + CIL DEMGLGKT Q+I F+Y GPFLI+
Sbjct: 857 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSIT-FLYEILLTGIRGPFLIIA 915
Query: 103 PLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQD-----------LKQESRFHVLLT 151
PLS ++NW+ E + + ++ V Y G R +QQ ++ RF ++T
Sbjct: 916 PLSTIANWEREFRTWTD-INVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIIT 974
Query: 152 TYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQ 211
T+E+ L L + W +++DEAHRLKN++ L + L ++ +LLTGTP+QN+++
Sbjct: 975 TFEMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVE 1034
Query: 212 ELYSLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASELHKLLQPFLLRRVKAEVATELP 271
EL+SLL F+EP F E F+Q + D++ E E +L +L+P +LRR+K +V +L
Sbjct: 1035 ELFSLLHFLEPLRFPSEST--FMQEFGDLKTE-EQVQKLQAILKPMMLRRLKEDVEKKLA 1091
Query: 272 KKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILS---QLRKCVDHPYLF 328
K E +I ++ +QKKYY+AIL K+ +F ++ A + + N+++ +LRKC +HPYL
Sbjct: 1092 PKEETIIEVELTNIQKKYYRAILEKNF-SFLSKGAGQTNVPNLVNTMMELRKCCNHPYLI 1150
Query: 329 DGVEPE----------PFEVGDHLT---EASGKLHLLDKLLAFLYSGGHRVLLFSQMTQM 375
G E + P HL +++GKL L+DKLL + +GGH+VL+FSQM +
Sbjct: 1151 KGAEEKILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRC 1210
Query: 376 LDILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPI--FVFLLSTRAGGVGMNLTAA 433
LDIL+DY+ ++ Y YER+DG VRG R AI F + FVFLL TRAGG+G+NLTAA
Sbjct: 1211 LDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAA 1270
Query: 434 DTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMI 493
DT I DSD+NPQNDLQA AR HRIGQNK+VKV RL+ R++ E ++ +A+ KL L +
Sbjct: 1271 DTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAV 1330
Query: 494 IE---GGHFTLGAQKPAADADLQLSEILK---FGLDKLLASEGSTMDEIDLESIL 542
++ G +G + + +++ ++L+ +G EGS E D++ IL
Sbjct: 1331 LQSMSGRESNVGGIQQLSKKEIE--DLLRRGAYGAIMEEEDEGSKFCEEDIDQIL 1383
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 358 bits (919), Expect = 1e-98
Identities = 267/761 (35%), Positives = 383/761 (50%), Gaps = 70/761 (9%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
L+ YQ++G+ WL ++ IL DEMGLGKT QTIAL YL GPFLI+ PLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
LSNW E ++AP + V+Y G R L+ +F+VLLTTYE +KD L
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRS-GKFNVLLTTYEYIIKDKHILAK 872
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDL 224
W ++VDE HR+KN L + L+ V LLLTGTP+QN L EL++LL+F+ P +
Sbjct: 873 IRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTI 932
Query: 225 FSKEEVGD------FIQRYQDIEKESESA----SELHKLLQPFLLRRVKAEVATELPKKT 274
F + F + ++ E LHK+L+PFLLRR+K EV +LP+K
Sbjct: 933 FKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKV 992
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLF 328
E VI MSALQ+ Y+ + K + + +E KK K L N + QLRK +HPY+F
Sbjct: 993 EYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMF 1052
Query: 329 DGVEPEPFE---------VGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDIL 379
+E E G L ASGK LLD++L L + H+VLLF QMT ++ I+
Sbjct: 1053 QHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIM 1112
Query: 380 QDYMDYRGYSYERVDGSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVI 437
+DY YRG+ Y R+DG+ + E+R + +K F + F+FLLSTRAGG+G+NL +ADTVI
Sbjct: 1113 EDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1172
Query: 438 FVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGG 497
DSD+NP DLQA RAHRIGQ V+V+RL ++VEE + A KL + +I+ G
Sbjct: 1173 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAG 1232
Query: 498 HFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETKDGQWVSDALPA 557
F + A LQ +L E +E E D + V+ +
Sbjct: 1233 MFDQKSSSHERRAFLQ----------AILEHEEQDEEE-------DEVPDDETVNQMI-- 1273
Query: 558 AEGGSRDQEEGK--NHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRN 615
+R +EE M L ++ ++ P ++ R E L +++ ++ R
Sbjct: 1274 ----ARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEED--ELPSWIIKDDAEVERLTCE 1327
Query: 616 KGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRL--IEEKKRQKEEAEHKKK 673
+ + G GS RK V + L ++Q + A + L IEE+ RQK+ + +K+
Sbjct: 1328 EEEEKMFG--RGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSSRKRKR 1385
Query: 674 MAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTHPQAGAED 733
+S+ S S S +D +ES + P A L ++T D
Sbjct: 1386 ----DSDAGSSTPTTSTRSRDKD----DESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVD 1437
Query: 734 ALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKD 774
A+I + SG +F L R P + YEL K D
Sbjct: 1438 AVIKYKDSSSGR-QLSEVFIQLPSRKELP-EYYELIRKPVD 1476
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 358 bits (918), Expect = 2e-98
Identities = 267/761 (35%), Positives = 383/761 (50%), Gaps = 71/761 (9%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
L+ YQ++G+ WL ++ IL DEMGLGKT QTIAL YL GPFLI+ PLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
LSNW E ++AP + V+Y G R L+ +F+VLLTTYE +KD L
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRS-GKFNVLLTTYEYIIKDKHILAK 872
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDL 224
W ++VDE HR+KN L + L+ V LLLTGTP+QN L EL++LL+F+ P +
Sbjct: 873 IRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTI 932
Query: 225 FSKEEVGD------FIQRYQDIEKESESA----SELHKLLQPFLLRRVKAEVATELPKKT 274
F + F + ++ E LHK+L+PFLLRR+K EV +LP+K
Sbjct: 933 FKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKV 992
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLF 328
E VI MSALQ+ Y+ + K + + +E KK K L N + QLRK +HPY+F
Sbjct: 993 EYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMF 1052
Query: 329 DGVEPEPFE---------VGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDIL 379
+E E G L ASGK LLD++L L + H+VLLF QMT ++ I+
Sbjct: 1053 QHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIM 1112
Query: 380 QDYMDYRGYSYERVDGSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVI 437
+DY YRG+ Y R+DG+ + E+R + +K F + F+FLLSTRAGG+G+NL +ADTVI
Sbjct: 1113 EDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1172
Query: 438 FVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGG 497
DSD+NP DLQA RAHRIGQ V+V+RL ++VEE + A KL + +I+ G
Sbjct: 1173 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAG 1232
Query: 498 HFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETKDGQWVSDALPA 557
F + A LQ +L E +E E D + V+ +
Sbjct: 1233 MFDQKSSSHERRAFLQ----------AILEHEEQDEEE-------DEVPDDETVNQMI-- 1273
Query: 558 AEGGSRDQEEGK--NHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRN 615
+R +EE M L ++ ++ P ++ R E L +++ ++ R
Sbjct: 1274 ----ARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEED--ELPSWIIKDDAEVERLTCE 1327
Query: 616 KGSVLIPGLVEGSTKRKRVLSPEELEDRQKKRQEAAAKRRRL--IEEKKRQKEEAEHKKK 673
+ + G GS RK V + L ++Q + A + L IEE+ RQK+ + +K+
Sbjct: 1328 EEEEKMFG--RGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSSRKRKR 1385
Query: 674 MAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTHPQAGAED 733
+S+ S S S +D +ES + P A L ++T D
Sbjct: 1386 ----DSDAGSSTPTTSTRSRDKD----DESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVD 1437
Query: 734 ALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKD 774
A+I + DS +F L R P + YEL K D
Sbjct: 1438 AVIKY--KDSSGRQLSEVFIQLPSRKELP-EYYELIRKPVD 1475
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 357 bits (916), Expect = 3e-98
Identities = 267/761 (35%), Positives = 383/761 (50%), Gaps = 73/761 (9%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
L+ YQ++G+ WL ++ IL DEMGLGKT QTIAL YL GPFLI+ PLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
LSNW E ++AP + V+Y G R L+ +F+VLLTTYE +KD L
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRS-GKFNVLLTTYEYIIKDKHILAK 872
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDL 224
W ++VDE HR+KN L + L+ V LLLTGTP+QN L EL++LL+F+ P +
Sbjct: 873 IRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTI 932
Query: 225 FSKEEVGD------FIQRYQDIEKESESA----SELHKLLQPFLLRRVKAEVATELPKKT 274
F + F + ++ E LHK+L+PFLLRR+K EV +LP+K
Sbjct: 933 FKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKV 992
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLF 328
E VI MSALQ+ Y+ + K + + +E KK K L N + QLRK +HPY+F
Sbjct: 993 EYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMF 1052
Query: 329 DGVEPEPFE---------VGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDIL 379
+E E G L ASGK LLD++L L + H+VLLF QMT ++ I+
Sbjct: 1053 QHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIM 1112
Query: 380 QDYMDYRGYSYERVDGSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVI 437
+DY YRG+ Y R+DG+ + E+R + +K F + F+FLLSTRAGG+G+NL +ADTVI
Sbjct: 1113 EDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1172
Query: 438 FVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGG 497
DSD+NP DLQA RAHRIGQ V+V+RL ++VEE + A KL + +I+ G
Sbjct: 1173 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAG 1232
Query: 498 HFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETKDGQWVSDALPA 557
F + A LQ +L E +E E D + V+ +
Sbjct: 1233 MFDQKSSSHERRAFLQ----------AILEHEEQDEEE-------DEVPDDETVNQMI-- 1273
Query: 558 AEGGSRDQEEGK--NHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRN 615
+R +EE M L ++ ++ P ++ R E L +++ ++ R
Sbjct: 1274 ----ARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEED--ELPSWIIKDDAEVERLTCE 1327
Query: 616 KGSVLIPGLVEGSTKRKRVLSPEELEDRQ--KKRQEAAAKRRRLIEEKKRQKEEAEHKKK 673
+ + G GS RK V + L ++Q K +E + IEE+ RQK+ + +K+
Sbjct: 1328 EEEEKMFG--RGSRHRKEVDYSDSLTEKQWLKAIEEGTLEE---IEEEVRQKKSSRKRKR 1382
Query: 674 MAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTHPQAGAED 733
+S+ S S S +D +ES + P A L ++T D
Sbjct: 1383 ----DSDAGSSTPTTSTRSRDKD----DESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVD 1434
Query: 734 ALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKD 774
A+I + SG +F L R P + YEL K D
Sbjct: 1435 AVIKYKDSSSGR-QLSEVFIQLPSRKELP-EYYELIRKPVD 1473
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 357 bits (915), Expect = 4e-98
Identities = 267/761 (35%), Positives = 383/761 (50%), Gaps = 74/761 (9%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
L+ YQ++G+ WL ++ IL DEMGLGKT QTIAL YL GPFLI+ PLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
LSNW E ++AP + V+Y G R L+ +F+VLLTTYE +KD L
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRS-GKFNVLLTTYEYIIKDKHILAK 872
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDL 224
W ++VDE HR+KN L + L+ V LLLTGTP+QN L EL++LL+F+ P +
Sbjct: 873 IRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTI 932
Query: 225 FSKEEVGD------FIQRYQDIEKESESA----SELHKLLQPFLLRRVKAEVATELPKKT 274
F + F + ++ E LHK+L+PFLLRR+K EV +LP+K
Sbjct: 933 FKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKV 992
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLF 328
E VI MSALQ+ Y+ + K + + +E KK K L N + QLRK +HPY+F
Sbjct: 993 EYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMF 1052
Query: 329 DGVEPEPFE---------VGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDIL 379
+E E G L ASGK LLD++L L + H+VLLF QMT ++ I+
Sbjct: 1053 QHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIM 1112
Query: 380 QDYMDYRGYSYERVDGSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVI 437
+DY YRG+ Y R+DG+ + E+R + +K F + F+FLLSTRAGG+G+NL +ADTVI
Sbjct: 1113 EDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1172
Query: 438 FVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGG 497
DSD+NP DLQA RAHRIGQ V+V+RL ++VEE + A KL + +I+ G
Sbjct: 1173 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAG 1232
Query: 498 HFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEIDLESILGETKDGQWVSDALPA 557
F + A LQ +L E +E E D + V+ +
Sbjct: 1233 MFDQKSSSHERRAFLQ----------AILEHEEQDEEE-------DEVPDDETVNQMI-- 1273
Query: 558 AEGGSRDQEEGK--NHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGRSLRN 615
+R +EE M L ++ ++ P ++ R E L +++ ++ R
Sbjct: 1274 ----ARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEED--ELPSWIIKDDAEVERLTCE 1327
Query: 616 KGSVLIPGLVEGSTKRKRVLSPEELEDRQ--KKRQEAAAKRRRLIEEKKRQKEEAEHKKK 673
+ + G GS RK V + L ++Q K +E + IEE+ RQK+ + +K+
Sbjct: 1328 EEEEKMFG--RGSRHRKEVDYSDSLTEKQWLKAIEEGTLEE---IEEEVRQKKSSRKRKR 1382
Query: 674 MAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVSGDVTHPQAGAED 733
+S+ S S S +D +ES + P A L ++T D
Sbjct: 1383 ----DSDAGSSTPTTSTRSRDKD----DESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVD 1434
Query: 734 ALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKD 774
A+I + DS +F L R P + YEL K D
Sbjct: 1435 AVIKY--KDSSGRQLSEVFIQLPSRKELP-EYYELIRKPVD 1472
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 353 bits (906), Expect = 4e-97
Identities = 270/773 (34%), Positives = 385/773 (49%), Gaps = 64/773 (8%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
L+ YQ++G+ WL ++ IL DEMGLGKT QTIAL YL GPFLI+ PLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
LSNW E ++AP + V+Y G R L+ +F+VLLTTYE +KD L
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRS-GKFNVLLTTYEYIIKDKHILAK 872
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDL 224
W ++VDE HR+KN L + L+ V LLLTGTP+QN L EL++LL+F+ P +
Sbjct: 873 IRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTI 932
Query: 225 FSKEEVGD------FIQRYQDIEKESESA----SELHKLLQPFLLRRVKAEVATELPKKT 274
F + F + ++ E LHK+L+PFLLRR+K EV +LP+K
Sbjct: 933 FKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKV 992
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLF 328
E VI MSALQ+ Y+ + K + + +E KK K L N + QLRK +HPY+F
Sbjct: 993 EYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMF 1052
Query: 329 DGVEPEPFE---------VGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDIL 379
+E E G L ASGK LLD++L L + H+VLLF QMT ++ I+
Sbjct: 1053 QHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIM 1112
Query: 380 QDYMDYRGYSYERVDGSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVI 437
+DY YRG+ Y R+DG+ + E+R + +K F + F+FLLSTRAGG+G+NL +ADTVI
Sbjct: 1113 EDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1172
Query: 438 FVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGG 497
DSD+NP DLQA RAHRIGQ V+V+RL ++VEE + A KL + +I+ G
Sbjct: 1173 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAG 1232
Query: 498 HFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEI------------DLESILGET 545
F + A LQ + + S GS DLE
Sbjct: 1233 MFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE--PPL 1290
Query: 546 KDGQWVSDALPAAEGGSRDQEEGK--NHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLL 603
K+ V D + +R +EE M L ++ ++ P ++ R E L ++
Sbjct: 1291 KEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEED--ELPSWII 1348
Query: 604 EKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQ--KKRQEAAAKRRRLIEEK 661
+ ++ R + + G GS RK V + L ++Q K +E + IEE+
Sbjct: 1349 KDDAEVERLTCEEEEEKMFG--RGSRHRKEVDYSDSLTEKQWLKAIEEGTLEE---IEEE 1403
Query: 662 KRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVS 721
RQK+ + +K+ +S+ S S S +D +ES + P A L
Sbjct: 1404 VRQKKSSRKRKR----DSDAGSSTPTTSTRSRDKD----DESKKQKKRGRPPAEKLSPNP 1455
Query: 722 GDVTHPQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKD 774
++T DA+I + SG +F L R P + YEL K D
Sbjct: 1456 PNLTKKMKKIVDAVIKYKDSSSGR-QLSEVFIQLPSRKELP-EYYELIRKPVD 1506
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 353 bits (906), Expect = 4e-97
Identities = 270/773 (34%), Positives = 385/773 (49%), Gaps = 64/773 (8%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
L+ YQ++G+ WL ++ IL DEMGLGKT QTIAL YL GPFLI+ PLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
LSNW E ++AP + V+Y G R L+ +F+VLLTTYE +KD L
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRS-GKFNVLLTTYEYIIKDKHILAK 872
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDL 224
W ++VDE HR+KN L + L+ V LLLTGTP+QN L EL++LL+F+ P +
Sbjct: 873 IRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTI 932
Query: 225 FSKEEVGD------FIQRYQDIEKESESA----SELHKLLQPFLLRRVKAEVATELPKKT 274
F + F + ++ E LHK+L+PFLLRR+K EV +LP+K
Sbjct: 933 FKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKV 992
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLF 328
E VI MSALQ+ Y+ + K + + +E KK K L N + QLRK +HPY+F
Sbjct: 993 EYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMF 1052
Query: 329 DGVEPEPFE---------VGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDIL 379
+E E G L ASGK LLD++L L + H+VLLF QMT ++ I+
Sbjct: 1053 QHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIM 1112
Query: 380 QDYMDYRGYSYERVDGSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVI 437
+DY YRG+ Y R+DG+ + E+R + +K F + F+FLLSTRAGG+G+NL +ADTVI
Sbjct: 1113 EDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1172
Query: 438 FVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGG 497
DSD+NP DLQA RAHRIGQ V+V+RL ++VEE + A KL + +I+ G
Sbjct: 1173 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAG 1232
Query: 498 HFTLGAQKPAADADLQLSEILKFGLDKLLASEGSTMDEI------------DLESILGET 545
F + A LQ + + S GS DLE
Sbjct: 1233 MFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE--PPL 1290
Query: 546 KDGQWVSDALPAAEGGSRDQEEGK--NHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLL 603
K+ V D + +R +EE M L ++ ++ P ++ R E L ++
Sbjct: 1291 KEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEED--ELPSWII 1348
Query: 604 EKASQEGRSLRNKGSVLIPGLVEGSTKRKRVLSPEELEDRQ--KKRQEAAAKRRRLIEEK 661
+ ++ R + + G GS RK V + L ++Q K +E + IEE+
Sbjct: 1349 KDDAEVERLTCEEEEEKMFG--RGSRHRKEVDYSDSLTEKQWLKAIEEGTLEE---IEEE 1403
Query: 662 KRQKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDLENGEESSAELDYQDPDATSLKYVS 721
RQK+ + +K+ +S+ S S S +D +ES + P A L
Sbjct: 1404 VRQKKSSRKRKR----DSDAGSSTPTTSTRSRDKD----DESKKQKKRGRPPAEKLSPNP 1455
Query: 722 GDVTHPQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKD 774
++T DA+I + SG +F L R P + YEL K D
Sbjct: 1456 PNLTKKMKKIVDAVIKYKDSSSGR-QLSEVFIQLPSRKELP-EYYELIRKPVD 1506
>gi|21914927 helicase, lymphoid-specific [Homo sapiens]
Length = 838
Score = 350 bits (898), Expect = 3e-96
Identities = 215/538 (39%), Positives = 303/538 (56%), Gaps = 78/538 (14%)
Query: 42 TGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLIL 101
TG +R YQ+EG+ WL + IL DEMGLGKT Q IA + R GPFL+
Sbjct: 219 TGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQR-GVPGPFLVC 277
Query: 102 CPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDL---KQESRFH-VLLTTYEICL 157
PLS L NW E +RF P + + Y G +EER L +++ K + H V++T++EI +
Sbjct: 278 GPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAM 337
Query: 158 KDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLL 217
+D + L+ W L+VDE HR+KN L + L F+ LLLTGTP+QN+L EL+SLL
Sbjct: 338 RDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLL 397
Query: 218 SFVEPDLF-------SKEEVGDFIQRYQDI---EKESESASELHKLLQPFLLRRVKAEVA 267
+F+ PD+F S ++ + +DI E+E LH++L PFLLRR+K++VA
Sbjct: 398 NFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVA 457
Query: 268 TELPKKTEVVIYHGMSALQKKYYKAILMKDL----------------------------- 298
E+P K EVV+Y +S Q+ +Y AI+ + +
Sbjct: 458 LEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSIN 517
Query: 299 ----DAFENETAKKV--------------------------KLQNILSQLRKCVDHPYLF 328
D F NE K + KLQNI+ LRKC +HPYL
Sbjct: 518 YSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLI 577
Query: 329 D-GVEP--EPFEVGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDY 385
+ ++P + F++ + L SGK +LD++L L GH+VLLFSQMT MLDIL DY
Sbjct: 578 EYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHL 637
Query: 386 RGYSYERVDGSVRGEERHLAIKNFGQQP-IFVFLLSTRAGGVGMNLTAADTVIFVDSDFN 444
R +++ R+DGS+ ER + +F P +F+FL+STRAGG+G+NLTAADTVI DSD+N
Sbjct: 638 RDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWN 697
Query: 445 PQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLG 502
PQ+DLQA R HRIGQ K V V RL+ +T+++ + +AA+K +L +II HF G
Sbjct: 698 PQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGG 755
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 350 bits (897), Expect = 4e-96
Identities = 206/482 (42%), Positives = 280/482 (58%), Gaps = 29/482 (6%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLS 105
L+ YQ++G+ WL ++ IL DEMGLGKT QTIAL YL GPFLI+ PLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 106 VLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKS 165
LSNW E ++AP + V+Y G R L+ +F+VLLTTYE +KD L
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRS-GKFNVLLTTYEYIIKDKHILAK 872
Query: 166 FPWSVLVVDEAHRLKNQSSLLHKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDL 224
W ++VDE HR+KN L + L+ V LLLTGTP+QN L EL++LL+F+ P +
Sbjct: 873 IRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTI 932
Query: 225 FSKEEVGD------FIQRYQDIEKESESA----SELHKLLQPFLLRRVKAEVATELPKKT 274
F + F + ++ E LHK+L+PFLLRR+K EV +LP+K
Sbjct: 933 FKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKV 992
Query: 275 EVVIYHGMSALQKKYYKAILMKDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLF 328
E VI MSALQ+ Y+ + K + + +E KK K L N + QLRK +HPY+F
Sbjct: 993 EYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMF 1052
Query: 329 DGVEPEPFE---------VGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDIL 379
+E E G L ASGK LLD++L L + H+VLLF QMT ++ I+
Sbjct: 1053 QHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIM 1112
Query: 380 QDYMDYRGYSYERVDGSVRGEERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVI 437
+DY YRG+ Y R+DG+ + E+R + +K F + F+FLLSTRAGG+G+NL +ADTVI
Sbjct: 1113 EDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1172
Query: 438 FVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGG 497
DSD+NP DLQA RAHRIGQ V+V+RL ++VEE + A KL + +I+ G
Sbjct: 1173 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAG 1232
Query: 498 HF 499
F
Sbjct: 1233 MF 1234
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 347 bits (891), Expect = 2e-95
Identities = 249/702 (35%), Positives = 363/702 (51%), Gaps = 64/702 (9%)
Query: 7 TSRGGQAPGFLLRLHTEGRAEAARVQEQDLRQWGLTGIHLRSYQLEGVNWLAQRFHCQNG 66
++RG Q+ +T A + RV++Q L L+ YQL+G+ W+ ++
Sbjct: 694 SARGSQS------YYTVAHAISERVEKQSAL---LINGTLKHYQLQGLEWMVSLYNNNLN 744
Query: 67 CILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLSVLSNWKEEMQRFAPGLSCVTY 126
IL DEMGLGKT QTIAL YL GP+LI+ PLS LSNW E ++AP + ++Y
Sbjct: 745 GILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISY 804
Query: 127 AGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLL 186
G R L L+ +F+VLLTTYE +KD L W ++VDE HR+KN L
Sbjct: 805 KGTPAMRRSLVPQLRS-GKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKL 863
Query: 187 HKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGD------FIQRYQD 239
+ L+ V +LLTGTP+QN L EL++LL+F+ P +F + F +
Sbjct: 864 TQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGER 923
Query: 240 IEKESESA----SELHKLLQPFLLRRVKAEVATELPKKTEVVIYHGMSALQKKYYKAILM 295
++ E LHK+L+PFLLRR+K EV ++LP+K E VI MSALQK Y+ +
Sbjct: 924 VDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQA 983
Query: 296 KDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLFDGVEPEPFEV---------GD 340
K + + +E KK K L N + QLRK +HPY+F +E E G
Sbjct: 984 KGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGA 1043
Query: 341 HLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGE 400
L ASGK LLD++L L + HRVLLF QMT ++ I++DY +R + Y R+DG+ + E
Sbjct: 1044 ELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSE 1103
Query: 401 ERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRI 458
+R +K F + F+FLLSTRAGG+G+NL AADTV+ DSD+NP DLQA RAHRI
Sbjct: 1104 DRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRI 1163
Query: 459 GQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEIL 518
GQ V+V+RL ++VEE + A KL + +I+ G F + A LQ IL
Sbjct: 1164 GQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQ--AIL 1221
Query: 519 KFGLDKLLASEGSTMDEIDLESILGETKDGQWVSDALPAAEGGSRDQEEGKN---HMYLF 575
+ E DE+ + L + + L R +E+ +N L
Sbjct: 1222 EH------EEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLM 1275
Query: 576 EGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQE--GRSLRNKGSVLIPGLVEGSTKRK- 632
E + K+D +++ E+ ++ GR R + V + T+++
Sbjct: 1276 EEDELPSWIIKDD-------AEVERLTCEEEEEKIFGRGSRQRRDV---DYSDALTEKQW 1325
Query: 633 -RVLSPEELEDRQKKRQEAAAKRRRLIEEKKRQKEEAEHKKK 673
R + LE+ +++ + KRRR + +K KE+ E KK
Sbjct: 1326 LRAIEDGNLEEMEEEVRLKKRKRRRNV-DKDPAKEDVEKAKK 1366
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 347 bits (891), Expect = 2e-95
Identities = 249/702 (35%), Positives = 363/702 (51%), Gaps = 64/702 (9%)
Query: 7 TSRGGQAPGFLLRLHTEGRAEAARVQEQDLRQWGLTGIHLRSYQLEGVNWLAQRFHCQNG 66
++RG Q+ +T A + RV++Q L L+ YQL+G+ W+ ++
Sbjct: 694 SARGSQS------YYTVAHAISERVEKQSAL---LINGTLKHYQLQGLEWMVSLYNNNLN 744
Query: 67 CILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLSVLSNWKEEMQRFAPGLSCVTY 126
IL DEMGLGKT QTIAL YL GP+LI+ PLS LSNW E ++AP + ++Y
Sbjct: 745 GILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISY 804
Query: 127 AGDKEERACLQQDLKQESRFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLL 186
G R L L+ +F+VLLTTYE +KD L W ++VDE HR+KN L
Sbjct: 805 KGTPAMRRSLVPQLRS-GKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKL 863
Query: 187 HKTLSEFSVV-FSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEEVGD------FIQRYQD 239
+ L+ V +LLTGTP+QN L EL++LL+F+ P +F + F +
Sbjct: 864 TQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGER 923
Query: 240 IEKESESA----SELHKLLQPFLLRRVKAEVATELPKKTEVVIYHGMSALQKKYYKAILM 295
++ E LHK+L+PFLLRR+K EV ++LP+K E VI MSALQK Y+ +
Sbjct: 924 VDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQA 983
Query: 296 KDLDAFE-NETAKKVK-----LQNILSQLRKCVDHPYLFDGVEPEPFEV---------GD 340
K + + +E KK K L N + QLRK +HPY+F +E E G
Sbjct: 984 KGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGA 1043
Query: 341 HLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGE 400
L ASGK LLD++L L + HRVLLF QMT ++ I++DY +R + Y R+DG+ + E
Sbjct: 1044 ELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSE 1103
Query: 401 ERHLAIKNFGQ--QPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRI 458
+R +K F + F+FLLSTRAGG+G+NL AADTV+ DSD+NP DLQA RAHRI
Sbjct: 1104 DRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRI 1163
Query: 459 GQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLSEIL 518
GQ V+V+RL ++VEE + A KL + +I+ G F + A LQ IL
Sbjct: 1164 GQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQ--AIL 1221
Query: 519 KFGLDKLLASEGSTMDEIDLESILGETKDGQWVSDALPAAEGGSRDQEEGKN---HMYLF 575
+ E DE+ + L + + L R +E+ +N L
Sbjct: 1222 EH------EEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLM 1275
Query: 576 EGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQE--GRSLRNKGSVLIPGLVEGSTKRK- 632
E + K+D +++ E+ ++ GR R + V + T+++
Sbjct: 1276 EEDELPSWIIKDD-------AEVERLTCEEEEEKIFGRGSRQRRDV---DYSDALTEKQW 1325
Query: 633 -RVLSPEELEDRQKKRQEAAAKRRRLIEEKKRQKEEAEHKKK 673
R + LE+ +++ + KRRR + +K KE+ E KK
Sbjct: 1326 LRAIEDGNLEEMEEEVRLKKRKRRRNV-DKDPAKEDVEKAKK 1366
>gi|190358536 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 262 bits (670), Expect = 9e-70
Identities = 182/507 (35%), Positives = 262/507 (51%), Gaps = 63/507 (12%)
Query: 44 IHLRSYQLEGVNWLAQ-RFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILC 102
+ L+ YQ G+NWLA H NG IL DEMGLGKT Q IA YL N+ GP LI+
Sbjct: 495 LSLKPYQKVGLNWLALVHKHGLNG-ILADEMGLGKTIQAIAFLAYLYQEGNN-GPHLIVV 552
Query: 103 PLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESR-FHVLLTTYEICLK--- 158
P S + NW E+ + P L + Y G +EER ++ ++ ++V++TTY +
Sbjct: 553 PASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSD 612
Query: 159 DASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLS 218
D S + + + DE H LKN S+ ++ L + LLLTGTP+QN+L EL SLL+
Sbjct: 613 DRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLN 672
Query: 219 FVEPDLFS---KEEVGDFIQRYQDIEKES----ESASELHKLLQPFLLRRVKAEVATELP 271
FV P +FS E F + + +++S E + ++++PF+LRRVK EV +LP
Sbjct: 673 FVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLP 732
Query: 272 KKTEVVIYHGMSALQKKYYKAILMKDLDAFEN-ETAKKVKLQNILSQLRKCVDHPYL--- 327
K + + MS Q++ Y + + + N T K ++ N++ QLRK +HP L
Sbjct: 733 PKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQ 792
Query: 328 ----------------------------FDGVEP----------------EPFEVGDHLT 343
F+ +E F++ L
Sbjct: 793 YYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLI 852
Query: 344 EASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERH 403
SGK +L +L+ L G RV+LFSQ T MLDIL+ + + + Y R+DG + ER
Sbjct: 853 LDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERI 912
Query: 404 LAIKNFG-QQPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNK 462
I F IFVFLLST+AGG+G+NLT+A+ VI D D NP ND QA R HR+GQ K
Sbjct: 913 HLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTK 972
Query: 463 SVKVIRLIGRDTVEEIVYRKAASKLQL 489
V VI+LI + T+EE + + KL+L
Sbjct: 973 EVLVIKLISQGTIEESMLKINQQKLKL 999
>gi|190358532 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 262 bits (670), Expect = 9e-70
Identities = 182/507 (35%), Positives = 262/507 (51%), Gaps = 63/507 (12%)
Query: 44 IHLRSYQLEGVNWLAQ-RFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILC 102
+ L+ YQ G+NWLA H NG IL DEMGLGKT Q IA YL N+ GP LI+
Sbjct: 495 LSLKPYQKVGLNWLALVHKHGLNG-ILADEMGLGKTIQAIAFLAYLYQEGNN-GPHLIVV 552
Query: 103 PLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESR-FHVLLTTYEICLK--- 158
P S + NW E+ + P L + Y G +EER ++ ++ ++V++TTY +
Sbjct: 553 PASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSD 612
Query: 159 DASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLS 218
D S + + + DE H LKN S+ ++ L + LLLTGTP+QN+L EL SLL+
Sbjct: 613 DRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLN 672
Query: 219 FVEPDLFS---KEEVGDFIQRYQDIEKES----ESASELHKLLQPFLLRRVKAEVATELP 271
FV P +FS E F + + +++S E + ++++PF+LRRVK EV +LP
Sbjct: 673 FVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLP 732
Query: 272 KKTEVVIYHGMSALQKKYYKAILMKDLDAFEN-ETAKKVKLQNILSQLRKCVDHPYL--- 327
K + + MS Q++ Y + + + N T K ++ N++ QLRK +HP L
Sbjct: 733 PKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQ 792
Query: 328 ----------------------------FDGVEP----------------EPFEVGDHLT 343
F+ +E F++ L
Sbjct: 793 YYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLI 852
Query: 344 EASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERH 403
SGK +L +L+ L G RV+LFSQ T MLDIL+ + + + Y R+DG + ER
Sbjct: 853 LDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERI 912
Query: 404 LAIKNFG-QQPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNK 462
I F IFVFLLST+AGG+G+NLT+A+ VI D D NP ND QA R HR+GQ K
Sbjct: 913 HLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTK 972
Query: 463 SVKVIRLIGRDTVEEIVYRKAASKLQL 489
V VI+LI + T+EE + + KL+L
Sbjct: 973 EVLVIKLISQGTIEESMLKINQQKLKL 999
>gi|190358534 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform b [Homo sapiens]
Length = 1026
Score = 262 bits (669), Expect = 1e-69
Identities = 183/506 (36%), Positives = 260/506 (51%), Gaps = 63/506 (12%)
Query: 44 IHLRSYQLEGVNWLAQ-RFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILC 102
+ L+ YQ G+NWLA H NG IL DEMGLGKT Q IA YL N+ GP LI+
Sbjct: 495 LSLKPYQKVGLNWLALVHKHGLNG-ILADEMGLGKTIQAIAFLAYLYQEGNN-GPHLIVV 552
Query: 103 PLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESR-FHVLLTTYEICLK--- 158
P S + NW E+ + P L + Y G +EER ++ ++ ++V++TTY +
Sbjct: 553 PASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSD 612
Query: 159 DASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLS 218
D S + + + DE H LKN S+ ++ L + LLLTGTP+QN+L EL SLL+
Sbjct: 613 DRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLN 672
Query: 219 FVEPDLFS---KEEVGDFIQRYQDIEKES----ESASELHKLLQPFLLRRVKAEVATELP 271
FV P +FS E F + + +++S E + ++++PF+LRRVK EV +LP
Sbjct: 673 FVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLP 732
Query: 272 KKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNILSQLRKCVDHPYL---- 327
K + + MS Q++ Y L L N K ++ N++ QLRK +HP L
Sbjct: 733 PKKDRIELCAMSEKQEQLYLG-LFNRLKKSINNLEKNTEMCNVMMQLRKMANHPLLHRQY 791
Query: 328 ---------------------------FDGVEP----------------EPFEVGDHLTE 344
F+ +E F++ L
Sbjct: 792 YTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLIL 851
Query: 345 ASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERHL 404
SGK +L +L+ L G RV+LFSQ T MLDIL+ + + + Y R+DG + ER
Sbjct: 852 DSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIH 911
Query: 405 AIKNFG-QQPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNKS 463
I F IFVFLLST+AGG+G+NLT+A+ VI D D NP ND QA R HR+GQ K
Sbjct: 912 LIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKE 971
Query: 464 VKVIRLIGRDTVEEIVYRKAASKLQL 489
V VI+LI + T+EE + + KL+L
Sbjct: 972 VLVIKLISQGTIEESMLKINQQKLKL 997
>gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription
factor-associated, 170kDa [Homo sapiens]
Length = 1849
Score = 236 bits (602), Expect = 7e-62
Identities = 185/572 (32%), Positives = 278/572 (48%), Gaps = 79/572 (13%)
Query: 46 LRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFI---------YLAGRLNDEG 96
LR YQ +GVNWLA + IL D+MGLGKT Q+I + Y +L +
Sbjct: 1266 LRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECM 1325
Query: 97 PF--LILCPLSVLSNWKEEMQRFAPG--LSCVTYAGDKEERACLQQDLKQESRFHVLLTT 152
P L++CP ++ +W +E+ +F L+ + Y G ER LQ +K R ++++ +
Sbjct: 1326 PLPSLVVCPPTLTGHWVDEVGKFCSREYLNPLHYTGPPTERIRLQHQVK---RHNLIVAS 1382
Query: 153 YEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQE 212
Y++ D F ++ ++ ++DE H +KN + L K + + + + ++L+GTPIQN++ E
Sbjct: 1383 YDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLE 1442
Query: 213 LYSLLSFVEPDLFSKEEVGDFIQRY----------QDIEKESESA----SELHKLLQPFL 258
L+SL F+ P E F RY + +E E+ LH+ + PFL
Sbjct: 1443 LWSLFDFLMPGFLGTER--QFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFL 1500
Query: 259 LRRVKAEVATELPKKTEVVIYHGMSALQKKYY----KAILMKDLD-----AFENETAKKV 309
LRR+K +V +LP K Y +S LQ + Y K+ D+D A +E +K
Sbjct: 1501 LRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKP 1560
Query: 310 KLQ------NILSQLRKCVDHPYL-FDGVEPEPFEVGDHLTEASGKLH------LLDKLL 356
KL+ L LRK +HP L PE + L + LH L L
Sbjct: 1561 KLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALK 1620
Query: 357 AFLYSGG-----------------HRVLLFSQMTQMLDILQDYM---DYRGYSYERVDGS 396
L G HR+L+F Q+ MLDI++ + +Y R+DGS
Sbjct: 1621 QLLLDCGLGNGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGS 1680
Query: 397 VRGEERHLAIKNFGQQP-IFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARA 455
+ +RH + F P I V LL+T GG+G+NLT ADTV+FV+ D+NP DLQA RA
Sbjct: 1681 IPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRA 1740
Query: 456 HRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQLS 515
HRIGQ + V V RLI R T+EE + K+ + N +I + +L Q D L L
Sbjct: 1741 HRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSL--QSMGTDQLLDLF 1798
Query: 516 EILKFGLDKLLASEGSTMDEIDLESILGETKD 547
+ K G K ++ ST + ++SIL D
Sbjct: 1799 TLDKDG--KAEKADTSTSGKASMKSILENLSD 1828
>gi|4557565 excision repair cross-complementing rodent repair
deficiency, complementation group 6 [Homo sapiens]
Length = 1493
Score = 229 bits (584), Expect = 9e-60
Identities = 158/490 (32%), Positives = 249/490 (50%), Gaps = 48/490 (9%)
Query: 46 LRSYQLEGVNWLAQRFHCQN-GCILGDEMGLGKTCQTIALFIYLAG-------------R 91
L YQ GV WL + HCQ G ILGDEMGLGKT Q IA +LAG R
Sbjct: 507 LFKYQQTGVRWLWE-LHCQQAGGILGDEMGLGKTIQIIA---FLAGLSYSKIRTRGSNYR 562
Query: 92 LNDEGPFLILCPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQDLKQESRFH-VLL 150
GP +I+CP +V+ W +E + P ++ ++ + H +L+
Sbjct: 563 FEGLGPTVIVCPTTVMHQWVKEFHTWWPPFRVAILHETGSYTHKKEKLIRDVAHCHGILI 622
Query: 151 TTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSL 210
T+Y + + W +++DE H+++N ++ + +F ++L+G+P+QN+L
Sbjct: 623 TSYSYIRLMQDDISRYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNL 682
Query: 211 QELYSLLSFVEPDLFSKEEVGDFIQRYQ--------------DIEKESESASELHKLLQP 256
+EL+SL F+ P V F++++ ++ + A L + P
Sbjct: 683 RELWSLFDFIFPGKLGTLPV--FMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINP 740
Query: 257 FLLRRVKAEV--ATELPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNI 314
+LLRR+K++V + LP K E V++ ++ Q K Y+ + D ++++ +
Sbjct: 741 YLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFV--DSKEVYRILNGEMQIFSG 798
Query: 315 LSQLRKCVDHPYLFDGVEPEPFEVGDHLTEA--------SGKLHLLDKLLAFLYSGGHRV 366
L LRK +HP LF G + D E SGK+ +++ LL + G RV
Sbjct: 799 LIALRKICNHPDLFSGGPKNLKGLPDDELEEDQFGYWKRSGKMIVVESLLKIWHKQGQRV 858
Query: 367 LLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQP-IFVFLLSTRAGG 425
LLFSQ QMLDIL+ ++ + Y+Y ++DG+ R I + + IFVFLL+TR GG
Sbjct: 859 LLFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYNEDTSIFVFLLTTRVGG 918
Query: 426 VGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAAS 485
+G+NLT A+ V+ D D+NP D QA RA RIGQ K V V RL+ T+EE +Y +
Sbjct: 919 LGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIF 978
Query: 486 KLQLTNMIIE 495
K LTN +++
Sbjct: 979 KQFLTNRVLK 988
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,914,444
Number of Sequences: 37866
Number of extensions: 1511580
Number of successful extensions: 10342
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 7337
Number of HSP's gapped (non-prelim): 1997
length of query: 897
length of database: 18,247,518
effective HSP length: 111
effective length of query: 786
effective length of database: 14,044,392
effective search space: 11038892112
effective search space used: 11038892112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.