Guide to the Human Genome
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Search of human proteins with 148596972

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148596972 zinc finger protein 365 isoform A [Homo sapiens]
         (407 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148596972 zinc finger protein 365 isoform A [Homo sapiens]         808   0.0  
gi|40789306 zinc finger protein 365 isoform C [Homo sapiens]          603   e-173
gi|40789310 zinc finger protein 365 isoform B [Homo sapiens]          603   e-172
gi|122937219 F-box protein 41 [Homo sapiens]                          135   7e-32
gi|5803145 ralA binding protein 1 [Homo sapiens]                       48   2e-05
gi|4758648 kinesin family member 5B [Homo sapiens]                     44   2e-04
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]    44   3e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    44   3e-04
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        44   3e-04
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       44   3e-04
gi|4504063 golgin 97 [Homo sapiens]                                    43   4e-04
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]          43   4e-04
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s...    43   4e-04
gi|122937345 myosin VB [Homo sapiens]                                  42   8e-04
gi|32484977 angiomotin like 2 [Homo sapiens]                           42   8e-04
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            42   0.001
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    41   0.002
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    41   0.002
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    41   0.002
gi|4506751 restin isoform a [Homo sapiens]                             41   0.002
gi|16262452 cingulin [Homo sapiens]                                    41   0.002
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    41   0.002
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    41   0.002
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    41   0.002
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    41   0.002
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    40   0.003
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]         40   0.003
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     40   0.003
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]    40   0.004
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 40   0.004

>gi|148596972 zinc finger protein 365 isoform A [Homo sapiens]
          Length = 407

 Score =  808 bits (2088), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 1   MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT 60
           MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT
Sbjct: 1   MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT 60

Query: 61  KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE 120
           KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE
Sbjct: 61  KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE 120

Query: 121 RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI 180
           RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI
Sbjct: 121 RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI 180

Query: 181 DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE 240
           DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE
Sbjct: 181 DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE 240

Query: 241 EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF 300
           EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF
Sbjct: 241 EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF 300

Query: 301 VRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPA 360
           VRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPA
Sbjct: 301 VRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPA 360

Query: 361 KAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII 407
           KAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII
Sbjct: 361 KAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII 407


>gi|40789306 zinc finger protein 365 isoform C [Homo sapiens]
          Length = 462

 Score =  603 bits (1556), Expect = e-173
 Identities = 317/352 (90%), Positives = 320/352 (90%), Gaps = 11/352 (3%)

Query: 1   MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT 60
           MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT
Sbjct: 1   MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT 60

Query: 61  KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE 120
           KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE
Sbjct: 61  KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE 120

Query: 121 RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI 180
           RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI
Sbjct: 121 RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI 180

Query: 181 DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE 240
           DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE
Sbjct: 181 DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE 240

Query: 241 EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF 300
           EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF
Sbjct: 241 EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF 300

Query: 301 VRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKD 352
           VRDLSGHV               G    VC + DL+        +HL   KD
Sbjct: 301 VRDLSGHV----------SWKGAGEARLVCQN-DLELEIFGHINHHLSGLKD 341


>gi|40789310 zinc finger protein 365 isoform B [Homo sapiens]
          Length = 333

 Score =  603 bits (1554), Expect = e-172
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT 60
           MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT
Sbjct: 1   MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT 60

Query: 61  KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE 120
           KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE
Sbjct: 61  KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE 120

Query: 121 RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI 180
           RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI
Sbjct: 121 RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI 180

Query: 181 DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE 240
           DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE
Sbjct: 181 DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE 240

Query: 241 EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF 300
           EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF
Sbjct: 241 EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF 300

Query: 301 VRDLSGHV 308
           VRDLSGHV
Sbjct: 301 VRDLSGHV 308


>gi|122937219 F-box protein 41 [Homo sapiens]
          Length = 936

 Score =  135 bits (340), Expect = 7e-32
 Identities = 109/347 (31%), Positives = 158/347 (45%), Gaps = 72/347 (20%)

Query: 24  LPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTK-----------------CSLFP 66
           LP RCPRCG+H RFRSLSSLRAHLE+SH+YE   +L+K                  S FP
Sbjct: 67  LPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFP 126

Query: 67  SLKDTDLVTS-----SELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSK------DRKPF 115
              +   + +      E+ +    Q         P+  +L    H H+       D  P 
Sbjct: 127 LAPEPAALLAVPGARREVFESTSFQGKEQAAGPSPAAPHLLHHHHHHAPLAHFPGDLVPA 186

Query: 116 EVVAER---------------------PVSYVQTYTAMDLHADSLDGTRSGPGL---PTS 151
            +  E                      P+  +    ++   A S      GPG    P S
Sbjct: 187 SLPCEELAEPGLVPAAAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCPGPAS 246

Query: 152 DTKAS-------FEAHVREKFNRMVE--AVDRTIEK-----------RIDKLTKELAQKT 191
            + AS       +E  +     R +E   VDR +E+           ++ +L  EL +K 
Sbjct: 247 ASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKA 306

Query: 192 AELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVV 251
           AEL   R    +L ++K+E++ R   L+RQVDV+VE++A L+Q L   E+EL RK++EVV
Sbjct: 307 AELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVV 366

Query: 252 TFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQAS 298
             + FL+  A +E   K RLQ FIE LL+R + AE+QL+   S   S
Sbjct: 367 QIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGS 413


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 58/269 (21%), Positives = 113/269 (42%), Gaps = 30/269 (11%)

Query: 148 LPTSDTKASFEAHVREKFNR---MVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQL 204
           + T  T    +A ++E+  R   ++  + R ++  I  L+KE       L EV+     L
Sbjct: 385 MATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKE-----ERLWEVQRILTAL 439

Query: 205 TQKKQEVQRRERALNRQVDVA-VEMIAVLRQRLTESEE----------ELLRKEEEVVTF 253
            +K +E +R+E       ++A +    V ++ + E+EE          E+L ++EE++  
Sbjct: 440 KRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVINILLAQENEILTEQEELLAM 499

Query: 254 NHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDIS 313
             FL      E +   RL+  I  +  R +    + E Y S+  S    +    ++ +  
Sbjct: 500 EQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSSESESESEDEEELQIILEDL 559

Query: 314 SNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDL 373
             +  +   + +  +   H + +A    + +  L         MQ AKA  +QA+   + 
Sbjct: 560 QRQNEELEIKNNHLNQAIHEEREAIIELRVQLRL-------LQMQRAKA-EQQAQEDEE- 610

Query: 374 CRPPKKGELLGFGRKGNIRPKMAKKKPTA 402
             P  +G  +   R G + PK AK++P A
Sbjct: 611 --PEWRGGAVQPPRDGVLEPKAAKEQPKA 637


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 5/145 (3%)

Query: 153 TKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQ 212
           +K   E     K  + +E+      K++++  KELA     + +  A    LT+  Q V+
Sbjct: 595 SKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVE 654

Query: 213 RRERALNRQVDVAVEMIAVLR--QRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKAR 270
           +++R L   VD   E +  LR  +++ E E+E L K   V T N   +A  ++    +  
Sbjct: 655 QKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNK---VQTANEVKQAVEQQIQSHRET 711

Query: 271 LQDFIENLLQRVELAEKQLEYYQSQ 295
            Q  I +L   VE   K +   Q Q
Sbjct: 712 HQKQISSLRDEVEAKAKLITDLQDQ 736


>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
          Length = 1498

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 25/183 (13%)

Query: 148  LPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQK 207
            L  S+ K   +A  +E   + ++A    ++ R  K ++E+AQ  AEL E RA  +QL QK
Sbjct: 1214 LELSEVKKELQA--KEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQ-LQLLQK 1270

Query: 208  KQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFL---EAAAEKE 264
                         Q+D  +    V  Q +   + E+ +KE E+ +    L   E    KE
Sbjct: 1271 -------------QLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKE 1317

Query: 265  VQGKARLQDFIENLLQRVELAEKQLEYYQSQQ--ASGFVRDLSGHVLTDISSNRKPKC-L 321
            ++G   LQ  ++N+   +E+A++ L   Q  +      V +L  ++ T +  N++ K  L
Sbjct: 1318 LEG---LQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDL 1374

Query: 322  SRG 324
             RG
Sbjct: 1375 RRG 1377



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 12/155 (7%)

Query: 153 TKASFEAHVREKFNRMVEAVDRT--IEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQ- 209
           +  S E+   E    M++ +     +E +++ L+ E +Q   E  E++A    L+ K Q 
Sbjct: 392 SSVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQA 451

Query: 210 ------EVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEK 263
                   Q+R+ +L+ +VD   +    L + +T+ +  L  K   + + N+ L+ A E+
Sbjct: 452 QVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQ 511

Query: 264 EVQGKARLQDFIENLLQR---VELAEKQLEYYQSQ 295
             +  A+++D   ++L +   V    +Q+   QSQ
Sbjct: 512 YQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQ 546



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 49/230 (21%), Positives = 93/230 (40%), Gaps = 35/230 (15%)

Query: 101 LYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLD---GTRSGPGLPTSDT---- 153
           L ++  EH    K   +  E   S  Q+  A+  H D L    G   G      DT    
Sbjct: 712 LEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLL 771

Query: 154 -------KASFEAHVREK------FNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAA 200
                  +A+ +A    K        R+ E  + T E  ++KL +ELA K+ ++  ++  
Sbjct: 772 QNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSET-LEKLREELAIKSGQVEHLQQE 830

Query: 201 FVQLTQKKQEVQRRERALNRQV------------DVAVEMIAVLRQRLTESEEELLRKEE 248
              L  KKQ  + +E+ L ++V            D  +  +   R+RL    +EL ++  
Sbjct: 831 TAAL--KKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELM 888

Query: 249 EVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQAS 298
           +V       EA   +  +  A+++  + +L   ++ A+K+ +  ++   S
Sbjct: 889 QVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQS 938


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 27/115 (23%), Positives = 60/115 (52%), Gaps = 3/115 (2%)

Query: 179 RIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTE 238
           ++ +  +EL  K  ELL+V+    ++  + +E++R+ + L  + ++  E +    +   E
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905

Query: 239 SEE---ELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLE 290
           +EE    L  K++E+    H LE+  E+E +    LQ+  + +   ++  E+QL+
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 32/144 (22%), Positives = 73/144 (50%), Gaps = 9/144 (6%)

Query: 158  EAHVREKFNR---MVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRR 214
            EA  REK  +   +  A++  +E + ++  ++  Q  A++ ++ ++   + +   E+++ 
Sbjct: 1475 EAEAREKETKALSLARALEEALEAK-EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKS 1533

Query: 215  ERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDF 274
            +RAL +QV+     +  L   L  +E+  LR E  +      ++A  E+++Q +    + 
Sbjct: 1534 KRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNM----QAMKAQFERDLQTRDEQNEE 1589

Query: 275  IENLL-QRVELAEKQLEYYQSQQA 297
             + LL ++V   E +LE  + Q+A
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRA 1613



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 15/169 (8%)

Query: 150  TSDTKASFEAHV---REKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVR--AAFVQL 204
            T D K   E ++   + +F R ++  D   E++   L K++ +  AEL + R   A    
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617

Query: 205  TQKKQEVQRRE-----RALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEA 259
            ++KK E+  ++      A N+  D  ++ +  L+ ++ + + EL   EE   + +     
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL---EEARASRDEIFAQ 1674

Query: 260  AAEKEVQGKARLQDF--IENLLQRVELAEKQLEYYQSQQASGFVRDLSG 306
            + E E + K+   +   ++  L   E A +  E  + + A       SG
Sbjct: 1675 SKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG 1723



 Score = 32.7 bits (73), Expect = 0.61
 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 8/95 (8%)

Query: 177  EKRIDKLTKELAQKTAEL---LEVRAAFVQL-TQKKQEVQRRERALNRQVDVAVEMIAVL 232
            EK+   L++EL     EL   L+  AA  +L T+++QEV   ++AL  +       I  +
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDM 1197

Query: 233  RQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQG 267
            RQR   + EEL  + E+   F    +A  EK  QG
Sbjct: 1198 RQRHATALEELSEQLEQAKRF----KANLEKNKQG 1228



 Score = 32.3 bits (72), Expect = 0.79
 Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 14/129 (10%)

Query: 169  VEAVDRT---IEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVA 225
            +EA ++    + K++ KL  ++     EL E RA+  ++  + +E +++ ++L  +    
Sbjct: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE---- 1688

Query: 226  VEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELA 285
               I  L++ L  SE      E+E       L         GK+ L D    L  R+   
Sbjct: 1689 ---ILQLQEELASSERARRHAEQE----RDELADEITNSASGKSALLDEKRRLEARIAQL 1741

Query: 286  EKQLEYYQS 294
            E++LE  QS
Sbjct: 1742 EEELEEEQS 1750



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 12/123 (9%)

Query: 177  EKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRL 236
            E++   L K   ++   + ++     +  + +QE+++ +R L+ +     + IA L+ ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078

Query: 237  TESEEELLRKEEEV-----------VTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELA 285
             E + +L +KEEE+           +  N+ L+   E + Q  A LQ+  E+       A
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQ-IAELQEDFESEKASRNKA 1137

Query: 286  EKQ 288
            EKQ
Sbjct: 1138 EKQ 1140


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 24/163 (14%)

Query: 150 TSDTKASFEAHVREKFN---RMVEAVDRTIEKRIDKLTKELAQKTAELLE-VRAAFVQLT 205
           +S  + + E  +R K     R +   +R + +R++   K+LA+K  E  E  R    QL 
Sbjct: 73  SSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLF 132

Query: 206 QKKQEVQRRERAL--------------NRQVDVAVEMIAVLRQRLTESEEELLRKEEEVV 251
            K +E QR +  L               R +++  + ++  + ++ + EEEL +K+  V 
Sbjct: 133 AKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVD 192

Query: 252 TFNHF------LEAAAEKEVQGKARLQDFIENLLQRVELAEKQ 288
                      L+AA EK  Q + RL+  +E  L+ + + ++Q
Sbjct: 193 KVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQ 235



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 33/116 (28%), Positives = 57/116 (49%), Gaps = 15/116 (12%)

Query: 200 AFVQLTQKKQEVQRRE-RALNRQVDVAVEMIAVLR------QRLTESEEELLRKEEEVVT 252
           A V   Q+  E+   E R L ++++   E +A L+      QR++E+ E L++   +   
Sbjct: 20  AIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSK--- 76

Query: 253 FNHFLEAAAEKEVQGKAR-LQDFIENLLQRVELAEKQL---EYYQSQQASGFVRDL 304
               LE A   +++G+ R + DF  +L +R+E A KQL   EY  S+     +  L
Sbjct: 77  -REALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQL 131


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 24/163 (14%)

Query: 150 TSDTKASFEAHVREKFN---RMVEAVDRTIEKRIDKLTKELAQKTAELLE-VRAAFVQLT 205
           +S  + + E  +R K     R +   +R + +R++   K+LA+K  E  E  R    QL 
Sbjct: 482 SSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLF 541

Query: 206 QKKQEVQRRERAL--------------NRQVDVAVEMIAVLRQRLTESEEELLRKEEEVV 251
            K +E QR +  L               R +++  + ++  + ++ + EEEL +K+  V 
Sbjct: 542 AKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVD 601

Query: 252 TFNHF------LEAAAEKEVQGKARLQDFIENLLQRVELAEKQ 288
                      L+AA EK  Q + RL+  +E  L+ + + ++Q
Sbjct: 602 KVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQ 644



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 33/116 (28%), Positives = 57/116 (49%), Gaps = 15/116 (12%)

Query: 200 AFVQLTQKKQEVQRRE-RALNRQVDVAVEMIAVLR------QRLTESEEELLRKEEEVVT 252
           A V   Q+  E+   E R L ++++   E +A L+      QR++E+ E L++   +   
Sbjct: 429 AIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSK--- 485

Query: 253 FNHFLEAAAEKEVQGKAR-LQDFIENLLQRVELAEKQL---EYYQSQQASGFVRDL 304
               LE A   +++G+ R + DF  +L +R+E A KQL   EY  S+     +  L
Sbjct: 486 -REALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQL 540


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 4/115 (3%)

Query: 176 IEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQR 235
           +E+ ++  T+EL++   EL+        L+QK +E+QR    L  Q D  +        +
Sbjct: 198 MEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESK 257

Query: 236 LTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLE 290
           +T  E+    KE+E+      L    +K        +D I +L ++V   EK+LE
Sbjct: 258 ITALEQ----KEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLE 308



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 50/235 (21%), Positives = 97/235 (41%), Gaps = 13/235 (5%)

Query: 38  RSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPS 97
           ++L   R  L  + S + + + T  +    L+ T L  S E L+    QS G V  Q+  
Sbjct: 329 QNLEDTRQQLLAARSSQAKAINTLETRVRELEQT-LQASEEQLQ----QSKGIVAAQETQ 383

Query: 98  YVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASF 157
              L + + E S  ++    + ++   +++   A++    +L+ TR+        T A  
Sbjct: 384 IQELAAANQESSHVQQQALALEQQ---FLERTQALEAQIVALERTRAA-----DQTTAEQ 435

Query: 158 EAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERA 217
                E+ N  ++      E+ +     EL +   E  +     V + Q  +EV+++   
Sbjct: 436 GMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQREE 495

Query: 218 LNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQ 272
             +Q      +I    Q L E  E LL+KE+E++       +A  +  Q +A L+
Sbjct: 496 FQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELE 550



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 173 DRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEM---- 228
           D+   +++D+L KE    TA+L E++   + L Q++ E+   E    +++     M    
Sbjct: 132 DQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKK 191

Query: 229 ---IAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEK 263
              +  + Q L     EL R +EE++  N      ++K
Sbjct: 192 EESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQK 229


>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
          Length = 1711

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/139 (25%), Positives = 68/139 (48%), Gaps = 10/139 (7%)

Query: 163 EKFNRMVEAVDRTIEKRIDKLTKELAQKTA--ELLEVRAAFVQLTQKKQEVQRRERALNR 220
           E   ++VEA +R   +  +       +K A  E  E+     +L  +KQ+V R+ R    
Sbjct: 544 ELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 603

Query: 221 QVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQ 280
           +++VA + +  +RQ +  +E+  LRKE E    +   EA+ E+      +L++  EN  +
Sbjct: 604 EMEVATQKVDAMRQEMRRAEK--LRKELEAQLDDAVAEASKER------KLREHSENFCK 655

Query: 281 RVELAEKQLEYYQSQQASG 299
           ++E   + L+  Q  + +G
Sbjct: 656 QMESELEALKVKQGGRGAG 674


>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
           sapiens]
          Length = 1719

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 8/134 (5%)

Query: 162 REKFNR-MVEAVDRTIEKRIDKLTKELAQKTA--ELLEVRAAFVQLTQKKQEVQRRERAL 218
           RE  N+ +V+A +R   +  +       +K A  E +E+     +L  +KQ++ R  R  
Sbjct: 544 REDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDK 603

Query: 219 NRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENL 278
             +VD+ ++ +  LRQ L  +E    R ++E+      L A A K+ + + + + + + L
Sbjct: 604 EEEVDLVMQKVESLRQELRRTE----RAKKELEVHTEALAAEASKDRKLREQSEHYSKQL 659

Query: 279 LQRVE-LAEKQLEY 291
              +E L +KQ+ Y
Sbjct: 660 ENELEGLKQKQISY 673


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 63/280 (22%), Positives = 125/280 (44%), Gaps = 38/280 (13%)

Query: 35   TRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPS----LKDTDLVTSSELLKPGKLQSSGN 90
            T  +   S R  LE +HS E+  L  + +        LKD     ++++L   K + + N
Sbjct: 990  TELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQN 1049

Query: 91   VVKQ----------KPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQT--YTAMDLHADS 138
             VK+          +  Y NL     E+S+  + ++ + +      QT  +     +  S
Sbjct: 1050 SVKENLMKKELEEERSRYQNLVK---EYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSS 1106

Query: 139  LDGTRSGPGLPTSDTKASFEAHVR-EKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEV 197
            L+   + P + TS+   + +A  + E+      A+D T+  ++ K  +EL Q+  +L   
Sbjct: 1107 LESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQ-- 1164

Query: 198  RAAFVQLTQKKQEVQRRERALNRQVDVAVEMIA-----VLRQRLTESEEELLRKEEEVVT 252
                VQL +++Q+  ++ +A   Q D+ ++  A      L+++  ESE + L+ +     
Sbjct: 1165 ----VQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKND----- 1215

Query: 253  FNHFLEAAAEKEVQGKAR--LQDFIENLLQRVELAEKQLE 290
             N   +A A++  Q  +     D    LL +++LA ++LE
Sbjct: 1216 LNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELE 1255


>gi|32484977 angiomotin like 2 [Homo sapiens]
          Length = 780

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 24/196 (12%)

Query: 151 SDTKASFEAHVREKFN---RMVEAVDRTIEKRIDKLTKELAQKTAE-------LLEVRAA 200
           S  + + E  +R K +   R ++  +R + +R++   + LA KT E       ++    A
Sbjct: 366 SSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLA 425

Query: 201 FVQLTQKKQEVQRRERAL--------NRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVT 252
                Q++QE   RE AL         R+ ++  + +   + R   +EEEL +K+  V  
Sbjct: 426 QSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEK 485

Query: 253 FNHF------LEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSG 306
                     L+AA EK  Q + RL+  +E  L+ +   ++Q         SG   +LS 
Sbjct: 486 VERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSA 545

Query: 307 HVLTDISSNRKPKCLS 322
             L++    ++ + L+
Sbjct: 546 LRLSEQLREKEEQILA 561



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 31/136 (22%), Positives = 64/136 (47%), Gaps = 6/136 (4%)

Query: 176 IEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVA--VEMIAVLR 233
           +E  +          +A L ++ A   +  + +++ +R +R L    + A  +E +    
Sbjct: 293 VEGPVSAQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEI 352

Query: 234 QRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQ 293
           QRL+E+ E L R   +       +    + E++   RLQDF  +L +R+E A ++L   +
Sbjct: 353 QRLSEAHESLTRASSKREALEKTMRNKMDSEMR---RLQDFNRDLRERLESANRRLA-SK 408

Query: 294 SQQASGFVRDLSGHVL 309
           +Q+A    +D+   +L
Sbjct: 409 TQEAQAGSQDMVAKLL 424


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 30/131 (22%), Positives = 60/131 (45%)

Query: 166 NRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVA 225
           N+M+  ++R  E+R+ +  + L ++   L E      +  ++ +E + R R    ++   
Sbjct: 187 NQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQ 246

Query: 226 VEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELA 285
            E +    +RL E EE L  +EE +      L    E+  + + RL++  E L ++ E  
Sbjct: 247 EERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERL 306

Query: 286 EKQLEYYQSQQ 296
            +Q E    Q+
Sbjct: 307 REQEERLCEQE 317



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 32/139 (23%), Positives = 60/139 (43%), Gaps = 5/139 (3%)

Query: 158 EAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERA 217
           E  +RE+  R+ E      E+R+ +  + L ++   L E      +  ++  E + R R 
Sbjct: 198 EERLREQEERLREQ-----EERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252

Query: 218 LNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIEN 277
              ++    E +    +RL E EE L  +EE +      L    E+  + + RL++  E 
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEER 312

Query: 278 LLQRVELAEKQLEYYQSQQ 296
           L ++ E   +Q E    Q+
Sbjct: 313 LCEQEERLREQEERLCEQE 331



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 19/154 (12%)

Query: 158 EAHVREKFNRMVEAVDRTIEK--RIDKLTKELAQKTAELLE----VRAAFVQLTQKKQEV 211
           E  +RE+  R+ E  +R  E+  R+ +  + L ++   L E    +R    +L ++++ +
Sbjct: 205 EERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERL 264

Query: 212 QRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARL 271
             +E  L  Q +   E      +RL E EE L  +EE +      L    E+  + + RL
Sbjct: 265 CEQEERLREQEERLHEQ----EERLCEQEERLREQEERLCEQEERLREQEERLCEQEERL 320

Query: 272 QDFIENLLQR---------VELAEKQLEYYQSQQ 296
           ++  E L ++         +E  EK LE  + Q+
Sbjct: 321 REQEERLCEQEKLPGQERLLEEVEKLLEQERRQE 354



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 34/158 (21%), Positives = 63/158 (39%), Gaps = 11/158 (6%)

Query: 150 TSDTKASFEAHVREKFNR-MVEAVDRTIE----------KRIDKLTKELAQKTAELLEVR 198
           TS  +   E H+ +K  R + +  ++T E           ++++L  E      EL  V 
Sbjct: 118 TSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVG 177

Query: 199 AAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLE 258
                  +  Q +    R    ++    E +    +RL E EE L  +EE +      L 
Sbjct: 178 RQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLR 237

Query: 259 AAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQ 296
              E+  + + RL++  E L ++ E   +Q E  + Q+
Sbjct: 238 EQEERLCEQEERLREHEERLCEQEERLCEQEERLREQE 275


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 35/148 (23%), Positives = 70/148 (47%), Gaps = 10/148 (6%)

Query: 150  TSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQ 209
            T + KA  EAH +   +   E      E +++ LTK   +   ++ ++  +  Q  + + 
Sbjct: 993  TKEKKALQEAHQQALDDLQAE------EDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM 1046

Query: 210  EVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKA 269
            +++R +R L   + +  E I  L     + +E L +K+ E+   N    A  E E    +
Sbjct: 1047 DLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN----ARIEDEQALGS 1102

Query: 270  RLQDFIENLLQRVELAEKQLEYYQSQQA 297
            +LQ  ++ L  R+E  E++LE  ++ +A
Sbjct: 1103 QLQKKLKELQARIEELEEELEAERTARA 1130



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 46/213 (21%), Positives = 88/213 (41%), Gaps = 39/213 (18%)

Query: 163  EKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQV 222
            E+    +EA +RT   +++KL  +L+++                  +E+  R        
Sbjct: 1116 EELEEELEA-ERTARAKVEKLRSDLSREL-----------------EEISERLEEAGGAT 1157

Query: 223  DVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAA--EKEVQGKARLQDFIENLLQ 280
             V +EM      +  E+E + +R++ E  T  H   AAA  +K     A L + I+NL +
Sbjct: 1158 SVQIEM-----NKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQR 1212

Query: 281  RVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFH 340
              +  EK+   ++ +             L D++SN +    ++ +   +C   + + + H
Sbjct: 1213 VKQKLEKEKSEFKLE-------------LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259

Query: 341  PKGRNHLKKAKDDRASMQPAKAIHEQAESSRDL 373
                   +++ +D  S Q AK   E  E SR L
Sbjct: 1260 RSKAEETQRSVNDLTS-QRAKLQTENGELSRQL 1291



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 26/138 (18%), Positives = 61/138 (44%), Gaps = 4/138 (2%)

Query: 161  VREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNR 220
            +RE++    EA    +++ + K   E+AQ   +        +Q T++ +E +++     +
Sbjct: 1343 LREQYEEETEA-KAELQRVLSKANSEVAQWRTKY---ETDAIQRTEELEEAKKKLAQRLQ 1398

Query: 221  QVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQ 280
            + + AVE +      L +++  L  + E+++       AAA    + +      +    Q
Sbjct: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458

Query: 281  RVELAEKQLEYYQSQQAS 298
            + E ++ +LE  Q +  S
Sbjct: 1459 KYEESQSELESSQKEARS 1476


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/141 (20%), Positives = 69/141 (48%), Gaps = 12/141 (8%)

Query: 158 EAHVREKFNRMVEAVDRTI--EKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRE 215
           E  +RE+  ++ E  ++    E++I +  +++ ++  E+        +  +K+QE   R+
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411

Query: 216 RALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFI 275
               R+ D          +++ E EEE+ R+EE++      ++   EK  + + ++Q+  
Sbjct: 412 EKKMREQD----------EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461

Query: 276 ENLLQRVELAEKQLEYYQSQQ 296
           E + ++ E  ++Q E  Q Q+
Sbjct: 462 EKMQEQEEKIQRQEEKIQEQE 482



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 48/257 (18%), Positives = 114/257 (44%), Gaps = 23/257 (8%)

Query: 41  SSLRAHLEFSHSYEERTL---LTKCSLFPSLK-DTDLVTSSELL-KPGKLQSSGNVVKQK 95
           S L   L F H+    T    LTK    PSL+   + +T  EL  K  +LQ    +V+ +
Sbjct: 174 SLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESE 233

Query: 96  PSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKA 155
            S + L     +   +R    +  ++          + + AD L     G  L +   K 
Sbjct: 234 KSEIQLNVKDLKRKLERAQLLLPQQQ----------LQVEADRL-----GKELQSVSAKL 278

Query: 156 SFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRE 215
             +    E +N + +  +  + ++ +K+ ++  +   + L++R    ++ ++++++  +E
Sbjct: 279 QAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE 338

Query: 216 RALNRQVDVA---VEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQ 272
             +  Q D      E I    +++ E EE++ R+EE++   +  ++   E+  + + +++
Sbjct: 339 EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398

Query: 273 DFIENLLQRVELAEKQL 289
           +  E   +++   EK++
Sbjct: 399 EQEEKRQEKMWRQEKKM 415



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 25/139 (17%), Positives = 70/139 (50%), Gaps = 1/139 (0%)

Query: 158 EAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERA 217
           E  +RE+ ++M    ++ I ++ +K+ ++  +   +  ++R    ++ ++++E+ R+E  
Sbjct: 338 EEKIREQEDKMWRQEEK-IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396

Query: 218 LNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIEN 277
           +  Q +   E +    +++ E +E++  +EEE+      +    E     + +L++  E 
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456

Query: 278 LLQRVELAEKQLEYYQSQQ 296
           + +  E  ++Q E  Q Q+
Sbjct: 457 MQEEEEKMQEQEEKIQRQE 475



 Score = 36.6 bits (83), Expect = 0.042
 Identities = 31/132 (23%), Positives = 65/132 (49%), Gaps = 7/132 (5%)

Query: 163 EKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQE----VQRRERAL 218
           EK     E + R  E++I +L + +  +  +L EV     +  +K QE    +QR+E  +
Sbjct: 420 EKIREQEEEMWRQ-EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478

Query: 219 NRQVDVAVEMIAVLRQ--RLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIE 276
             Q +       +L+Q  ++ E EE++ R+EE++      ++   EK  + + ++++   
Sbjct: 479 QEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEV 538

Query: 277 NLLQRVELAEKQ 288
            L Q+ E  ++Q
Sbjct: 539 RLWQQEEKMQEQ 550



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 31/129 (24%), Positives = 64/129 (49%), Gaps = 6/129 (4%)

Query: 158 EAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERA 217
           E  +RE   +M E  ++  E+  +K+ ++  +K  E  E      +L ++++++  +E  
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQE-EKIQRQ-EEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504

Query: 218 LNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIEN 277
           + RQ +   E      +++ E EE++ R+EE++      L    EK  + + RLQ+  E 
Sbjct: 505 MWRQEEKMWEQ----EEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560

Query: 278 LLQRVELAE 286
           L +  + AE
Sbjct: 561 LGKLGQKAE 569



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 28/128 (21%), Positives = 63/128 (49%), Gaps = 7/128 (5%)

Query: 176 IEKRIDKLTKELAQKTAEL---LEVRAAFVQLTQKKQE-VQRRERALNRQVDVAVEMIAV 231
           ++   D+L KEL   +A+L   +E    +  L Q+++E + R+E  +  Q +   E    
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319

Query: 232 LRQ---RLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQ 288
           +R+   ++   EE++  +EE++      +    EK  + + ++++  E + ++ E   +Q
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379

Query: 289 LEYYQSQQ 296
            E  Q Q+
Sbjct: 380 DEKIQEQE 387



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 23/136 (16%), Positives = 66/136 (48%), Gaps = 2/136 (1%)

Query: 163 EKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQV 222
           E+  R  E +    EKR +K+ ++  +   +  ++R    ++ +++++++  E  +  Q 
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447

Query: 223 DVAVEMIAVLRQR--LTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQ 280
           +   E+   +++     + +EE ++++EE +          EK ++ + ++ +  E + +
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507

Query: 281 RVELAEKQLEYYQSQQ 296
           + E   +Q E  Q Q+
Sbjct: 508 QEEKMWEQEEKMQEQE 523


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/141 (20%), Positives = 69/141 (48%), Gaps = 12/141 (8%)

Query: 158 EAHVREKFNRMVEAVDRTI--EKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRE 215
           E  +RE+  ++ E  ++    E++I +  +++ ++  E+        +  +K+QE   R+
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411

Query: 216 RALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFI 275
               R+ D          +++ E EEE+ R+EE++      ++   EK  + + ++Q+  
Sbjct: 412 EKKMREQD----------EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461

Query: 276 ENLLQRVELAEKQLEYYQSQQ 296
           E + ++ E  ++Q E  Q Q+
Sbjct: 462 EKMQEQEEKIQRQEEKIQEQE 482



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 25/139 (17%), Positives = 70/139 (50%), Gaps = 1/139 (0%)

Query: 158 EAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERA 217
           E  +RE+ ++M    ++ I ++ +K+ ++  +   +  ++R    ++ ++++E+ R+E  
Sbjct: 338 EEKIREQEDKMWRQEEK-IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396

Query: 218 LNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIEN 277
           +  Q +   E +    +++ E +E++  +EEE+      +    E     + +L++  E 
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456

Query: 278 LLQRVELAEKQLEYYQSQQ 296
           + +  E  ++Q E  Q Q+
Sbjct: 457 MQEEEEKMQEQEEKIQRQE 475



 Score = 36.6 bits (83), Expect = 0.042
 Identities = 31/132 (23%), Positives = 65/132 (49%), Gaps = 7/132 (5%)

Query: 163 EKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQE----VQRRERAL 218
           EK     E + R  E++I +L + +  +  +L EV     +  +K QE    +QR+E  +
Sbjct: 420 EKIREQEEEMWRQ-EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478

Query: 219 NRQVDVAVEMIAVLRQ--RLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIE 276
             Q +       +L+Q  ++ E EE++ R+EE++      ++   EK  + + ++++   
Sbjct: 479 QEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEV 538

Query: 277 NLLQRVELAEKQ 288
            L Q+ E  ++Q
Sbjct: 539 RLWQQEEKMQEQ 550



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 24/154 (15%), Positives = 76/154 (49%), Gaps = 3/154 (1%)

Query: 139 LDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVR 198
           ++  R G  L +   K   +    E +N + +  +  + ++ +K+ ++  +   + L++R
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321

Query: 199 AAFVQLTQKKQEVQRRERALNRQVDVA---VEMIAVLRQRLTESEEELLRKEEEVVTFNH 255
               ++ ++++++  +E  +  Q D      E I    +++ E EE++ R+EE++   + 
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381

Query: 256 FLEAAAEKEVQGKARLQDFIENLLQRVELAEKQL 289
            ++   E+  + + ++++  E   +++   EK++
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 31/129 (24%), Positives = 64/129 (49%), Gaps = 6/129 (4%)

Query: 158 EAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERA 217
           E  +RE   +M E  ++  E+  +K+ ++  +K  E  E      +L ++++++  +E  
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQE-EKIQRQ-EEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504

Query: 218 LNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIEN 277
           + RQ +   E      +++ E EE++ R+EE++      L    EK  + + RLQ+  E 
Sbjct: 505 MWRQEEKMWEQ----EEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560

Query: 278 LLQRVELAE 286
           L +  + AE
Sbjct: 561 LGKLGQKAE 569



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 28/128 (21%), Positives = 63/128 (49%), Gaps = 7/128 (5%)

Query: 176 IEKRIDKLTKELAQKTAEL---LEVRAAFVQLTQKKQE-VQRRERALNRQVDVAVEMIAV 231
           ++   D+L KEL   +A+L   +E    +  L Q+++E + R+E  +  Q +   E    
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319

Query: 232 LRQ---RLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQ 288
           +R+   ++   EE++  +EE++      +    EK  + + ++++  E + ++ E   +Q
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379

Query: 289 LEYYQSQQ 296
            E  Q Q+
Sbjct: 380 DEKIQEQE 387



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 23/136 (16%), Positives = 66/136 (48%), Gaps = 2/136 (1%)

Query: 163 EKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQV 222
           E+  R  E +    EKR +K+ ++  +   +  ++R    ++ +++++++  E  +  Q 
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447

Query: 223 DVAVEMIAVLRQR--LTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQ 280
           +   E+   +++     + +EE ++++EE +          EK ++ + ++ +  E + +
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507

Query: 281 RVELAEKQLEYYQSQQ 296
           + E   +Q E  Q Q+
Sbjct: 508 QEEKMWEQEEKMQEQE 523


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 45/190 (23%), Positives = 82/190 (43%), Gaps = 23/190 (12%)

Query: 163 EKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQV 222
           ++   MVEA DR   + +++L +E  ++  E L+ R     +T+   E Q +        
Sbjct: 411 DQLRTMVEAADREKVELLNQLEEE--KRKVEDLQFRVEEESITKGDLETQTK-------- 460

Query: 223 DVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRV 282
                   +   R+ E E+ LL ++ +       LE      V  K+R+ +  ++L  RV
Sbjct: 461 --------LEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRV 512

Query: 283 ELAEKQLEYYQSQQASGFVRDLSGHVLTDISS-NRKPKCLSRGHPHSVCNHPDLKAHFHP 341
           +   +     +S + +G V D+S  +L +ISS   K +     H   + +   LK HF  
Sbjct: 513 QEVAELRRRLESNKPAGDV-DMSLSLLQEISSLQEKLEVTRTDHQREITS---LKEHFGA 568

Query: 342 KGRNHLKKAK 351
           +   H K+ K
Sbjct: 569 REETHQKEIK 578



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 21/112 (18%), Positives = 50/112 (44%), Gaps = 18/112 (16%)

Query: 169 VEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEM 228
           V  V  T+EK +  L ++ A+ + E + V+ +  +   K  + + +   L+  ++     
Sbjct: 831 VSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEK---- 886

Query: 229 IAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQ 280
              LR+ L + E +   K+E             E+ ++ K +L++ I  +++
Sbjct: 887 ---LRENLADMEAKFREKDER-----------EEQLIKAKEKLENDIAEIMK 924


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/148 (23%), Positives = 68/148 (45%), Gaps = 5/148 (3%)

Query: 152 DTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEV 211
           D   + EA +R+K  R+ EA  + +E+ ++   +E     A    + A   +  +    +
Sbjct: 754 DGGEAVEARLRDKLQRL-EAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARL 812

Query: 212 QRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQG---- 267
            + ++ LNR ++   +   VLR+   E EE+    +  V   N  LE   E   Q     
Sbjct: 813 GQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQL 872

Query: 268 KARLQDFIENLLQRVELAEKQLEYYQSQ 295
           +A+L+D+ E   + V  A++Q + + S+
Sbjct: 873 QAQLEDYKEKARREVADAQRQAKDWASE 900



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 35/147 (23%), Positives = 70/147 (47%), Gaps = 14/147 (9%)

Query: 162 REKFNRMVEAVDRTIEKRIDKLT--KELAQKTAELLEVRAAFVQLTQKKQEVQRRERALN 219
           R+K + +V  + R +E+  ++    + + QK  E  ++RA   +L Q + E +  E  L 
Sbjct: 547 RQKMSALVRGLQRELEETSEETGHWQSMFQKNKE--DLRATKQELLQLRMEKEEMEEELG 604

Query: 220 RQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEK---EVQGKARLQDFIE 276
            +++V    +   R    ++ +  + K+E + T     E  AE+   EV G+ R ++  +
Sbjct: 605 EKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEK 664

Query: 277 NL-LQRV------ELAEKQLEYYQSQQ 296
            L + RV      EL E+ L+  ++ Q
Sbjct: 665 QLAVLRVEADRGRELEEQNLQLQKTLQ 691



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 31/136 (22%), Positives = 63/136 (46%), Gaps = 18/136 (13%)

Query: 171 AVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQ-------LTQKKQEVQRRERALNRQVD 223
           A  R +E R+++  + LA+   E   +  A  +       L + K E++ ++R L+R VD
Sbjct: 793 AAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVD 852

Query: 224 V-----------AVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQ 272
                       + + +  L+ +L + +E+  R+  +         + AEK   G +RLQ
Sbjct: 853 RLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQ 912

Query: 273 DFIENLLQRVELAEKQ 288
           D I+ L Q ++ ++ +
Sbjct: 913 DEIQRLRQALQASQAE 928



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 36/181 (19%), Positives = 76/181 (41%), Gaps = 30/181 (16%)

Query: 140 DGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKL----------TKELA- 188
           D   + P       KA+    +RE  +    +V R +   ++K+          TK +A 
Sbjct: 301 DQQEAAPPGSVDHMKATIYGILREGSSESETSVRRKVSLVLEKMQPLVMVSSGSTKAVAG 360

Query: 189 --QKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRK 246
             + T ++ E++    +  +K+Q+++  +  L RQ++   E  + L++ L   + E  + 
Sbjct: 361 QGELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQS 420

Query: 247 EEEVVTFNHFLEAAAE----------------KEVQGKARLQD-FIENLLQRVELAEKQL 289
            +E+      L+   +                K VQG    ++  +++LL+  EL E+ L
Sbjct: 421 NKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVL 480

Query: 290 E 290
           E
Sbjct: 481 E 481



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 33/148 (22%), Positives = 63/148 (42%), Gaps = 15/148 (10%)

Query: 152 DTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEV-----RAAFVQLTQ 206
           D +   E  V E  N++         K +  L K+L + T ELLE      +    QL  
Sbjct: 436 DLRHGLETQVMELQNKLKHVQGPEPAKEV--LLKDLLE-TRELLEEVLEGKQRVEEQLRL 492

Query: 207 KKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQ 266
           +++E+   + AL  +V    + +  +RQ+     E+L R  ++    +  LEA  +K   
Sbjct: 493 RERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQK--- 549

Query: 267 GKARLQDFIENLLQRVELAEKQLEYYQS 294
               +   +  L + +E   ++  ++QS
Sbjct: 550 ----MSALVRGLQRELEETSEETGHWQS 573



 Score = 29.3 bits (64), Expect = 6.7
 Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 25/160 (15%)

Query: 133  DLHADSLDGTRSGPGLPTSDTKASFEAHVREKFN-RMVEAVDRTIEKRI--DKLTKELAQ 189
            DL  D +   R    L T    AS E   +   +   +E+ ++ +++R+  ++  K + Q
Sbjct: 1015 DLECDKISLERQNKDLKTR--LASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQ 1072

Query: 190  KTAELLE--VRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKE 247
             T   LE  V+   +Q+  ++Q V       N Q D     +  L++++ E+EEE+ R +
Sbjct: 1073 STNRKLERKVKELSIQIEDERQHV-------NDQKDQLSLRVKALKRQVDEAEEEIERLD 1125

Query: 248  EEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEK 287
                     L   A++EV+ +  +    E L  R++  EK
Sbjct: 1126 G--------LRKKAQREVEEQHEVN---EQLQARIKSLEK 1154



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 37/135 (27%), Positives = 56/135 (41%), Gaps = 22/135 (16%)

Query: 185 KELAQKTAELLEVRAAFVQLT-----QKKQEVQRRERALNRQ-------VDVAVEMIAVL 232
           K +A+  A +L  R A V+ T     ++  E +RR   L +Q       VD    + A L
Sbjct: 704 KMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARL 763

Query: 233 RQRLTESEEELLRKEE----------EVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRV 282
           R +L   E E  + EE           +      LEA  E+  +G ARL    + L + +
Sbjct: 764 RDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRAL 823

Query: 283 ELAEKQLEYYQSQQA 297
           E   KQ E  +  +A
Sbjct: 824 EEEGKQREVLRRGKA 838


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/254 (21%), Positives = 111/254 (43%), Gaps = 17/254 (6%)

Query: 133  DLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIE--KRIDKLTKELAQK 190
            +L +   DG R+   L  +D     +  V      + EA  + I+  K +  L+ +L Q 
Sbjct: 1263 ELQSKCSDGERARAEL--NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL-QD 1319

Query: 191  TAELL-EVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEE 249
            T ELL E     + ++ K ++++    +L  Q+D  +E    L + ++    +L   +++
Sbjct: 1320 TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK 1379

Query: 250  VVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVL 309
            +  F   +EA  E    GK R Q  IENL Q+ E  EK   Y + ++    ++     ++
Sbjct: 1380 LQDFASTVEALEE----GKKRFQKEIENLTQQYE--EKAAAYDKLEKTKNRLQQELDDLV 1433

Query: 310  TDISSNRK----PKCLSRGHPHSVCNHPDLKAHF-HPKGRNHLKKAKDDRASMQPAKAIH 364
             D+ + R+     +   R     +    ++ + +   + R   +  + +  ++  A+A+ 
Sbjct: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493

Query: 365  EQAESSRDLCRPPK 378
            E  E+  +L R  K
Sbjct: 1494 EALEAKEELERTNK 1507



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 50/227 (22%), Positives = 90/227 (39%), Gaps = 48/227 (21%)

Query: 154  KASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAE--------------LLEVRA 199
            K   E  V +  N  +    + +E+RI  LT  LA++  +              + E+  
Sbjct: 982  KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1041

Query: 200  AFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEA 259
               +  + +QE+++ +R L        E IA L+ ++ E + +L +KEEE       L+A
Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE-------LQA 1094

Query: 260  AAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPK 319
            A        ARL D         E+A+K     + ++  G + DL   + ++ ++  K +
Sbjct: 1095 AL-------ARLDD---------EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138

Query: 320  CLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQ 366
               R          DL        +  L+   D  A+ Q  +A  EQ
Sbjct: 1139 KQKR----------DLGEELEAL-KTELEDTLDSTATQQELRAKREQ 1174



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 48/229 (20%), Positives = 97/229 (42%), Gaps = 34/229 (14%)

Query: 151  SDTKASFEAHVREKFNR---MVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQK 207
            +D +   EA  REK  +   +  A++  +E + ++L +      AE+ ++ ++   + + 
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKN 1526

Query: 208  KQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQG 267
              E+++ +RAL  Q++     +  L   L  +E+  LR E  +      L+   E+++Q 
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM----QALKGQFERDLQA 1582

Query: 268  KARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPH 327
            +    +     LQR      QL  Y+                T++   RK + L+     
Sbjct: 1583 RDEQNEEKRRQLQR------QLHEYE----------------TELEDERKQRALAAAAKK 1620

Query: 328  SV---CNHPDLKAHFHPKGRNH-LKKAKDDRASMQPAKAIHEQAESSRD 372
             +       +L+A    KGR   +K+ +  +A M+  +   E A +SRD
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1669



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 12/108 (11%)

Query: 184 TKELAQKTA-ELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEE 242
           TKE  QK   EL E+     QLT++K  +Q + +A       A EM    R RL   ++E
Sbjct: 864 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM----RVRLAAKKQE 919

Query: 243 LLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLE 290
           L    EE++   H +EA  E+E     +LQ   + + Q++   E+QLE
Sbjct: 920 L----EEIL---HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 29/122 (23%), Positives = 63/122 (51%), Gaps = 12/122 (9%)

Query: 178  KRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLT 237
            K+I +L   ++    +L   RAA  +  ++K+++     AL  +++  ++         T
Sbjct: 1111 KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS--------T 1162

Query: 238  ESEEELLRKEEEVVTFNHFLEAAAEKEVQG-KARLQDFIENLLQRVELAEKQLEYYQSQQ 296
             +++EL  K E+ VT    L+ A ++E +  +A++Q+  +   Q VE   +QLE ++  +
Sbjct: 1163 ATQQELRAKREQEVT---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219

Query: 297  AS 298
            A+
Sbjct: 1220 AN 1221


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/254 (21%), Positives = 111/254 (43%), Gaps = 17/254 (6%)

Query: 133  DLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIE--KRIDKLTKELAQK 190
            +L +   DG R+   L  +D     +  V      + EA  + I+  K +  L+ +L Q 
Sbjct: 1270 ELQSKCSDGERARAEL--NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL-QD 1326

Query: 191  TAELL-EVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEE 249
            T ELL E     + ++ K ++++    +L  Q+D  +E    L + ++    +L   +++
Sbjct: 1327 TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK 1386

Query: 250  VVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVL 309
            +  F   +EA  E    GK R Q  IENL Q+ E  EK   Y + ++    ++     ++
Sbjct: 1387 LQDFASTVEALEE----GKKRFQKEIENLTQQYE--EKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 310  TDISSNRK----PKCLSRGHPHSVCNHPDLKAHF-HPKGRNHLKKAKDDRASMQPAKAIH 364
             D+ + R+     +   R     +    ++ + +   + R   +  + +  ++  A+A+ 
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500

Query: 365  EQAESSRDLCRPPK 378
            E  E+  +L R  K
Sbjct: 1501 EALEAKEELERTNK 1514



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 50/227 (22%), Positives = 90/227 (39%), Gaps = 48/227 (21%)

Query: 154  KASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAE--------------LLEVRA 199
            K   E  V +  N  +    + +E+RI  LT  LA++  +              + E+  
Sbjct: 989  KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1048

Query: 200  AFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEA 259
               +  + +QE+++ +R L        E IA L+ ++ E + +L +KEEE       L+A
Sbjct: 1049 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE-------LQA 1101

Query: 260  AAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPK 319
            A        ARL D         E+A+K     + ++  G + DL   + ++ ++  K +
Sbjct: 1102 AL-------ARLDD---------EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145

Query: 320  CLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQ 366
               R          DL        +  L+   D  A+ Q  +A  EQ
Sbjct: 1146 KQKR----------DLGEELEAL-KTELEDTLDSTATQQELRAKREQ 1181



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 48/229 (20%), Positives = 97/229 (42%), Gaps = 34/229 (14%)

Query: 151  SDTKASFEAHVREKFNR---MVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQK 207
            +D +   EA  REK  +   +  A++  +E + ++L +      AE+ ++ ++   + + 
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKN 1533

Query: 208  KQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQG 267
              E+++ +RAL  Q++     +  L   L  +E+  LR E  +      L+   E+++Q 
Sbjct: 1534 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM----QALKGQFERDLQA 1589

Query: 268  KARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPH 327
            +    +     LQR      QL  Y+                T++   RK + L+     
Sbjct: 1590 RDEQNEEKRRQLQR------QLHEYE----------------TELEDERKQRALAAAAKK 1627

Query: 328  SV---CNHPDLKAHFHPKGRNH-LKKAKDDRASMQPAKAIHEQAESSRD 372
             +       +L+A    KGR   +K+ +  +A M+  +   E A +SRD
Sbjct: 1628 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1676



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 12/108 (11%)

Query: 184 TKELAQKTA-ELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEE 242
           TKE  QK   EL E+     QLT++K  +Q + +A       A EM    R RL   ++E
Sbjct: 871 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM----RVRLAAKKQE 926

Query: 243 LLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLE 290
           L    EE++   H +EA  E+E     +LQ   + + Q++   E+QLE
Sbjct: 927 L----EEIL---HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 29/122 (23%), Positives = 63/122 (51%), Gaps = 12/122 (9%)

Query: 178  KRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLT 237
            K+I +L   ++    +L   RAA  +  ++K+++     AL  +++  ++         T
Sbjct: 1118 KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS--------T 1169

Query: 238  ESEEELLRKEEEVVTFNHFLEAAAEKEVQG-KARLQDFIENLLQRVELAEKQLEYYQSQQ 296
             +++EL  K E+ VT    L+ A ++E +  +A++Q+  +   Q VE   +QLE ++  +
Sbjct: 1170 ATQQELRAKREQEVT---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 297  AS 298
            A+
Sbjct: 1227 AN 1228


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/254 (21%), Positives = 111/254 (43%), Gaps = 17/254 (6%)

Query: 133  DLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIE--KRIDKLTKELAQK 190
            +L +   DG R+   L  +D     +  V      + EA  + I+  K +  L+ +L Q 
Sbjct: 1270 ELQSKCSDGERARAEL--NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL-QD 1326

Query: 191  TAELL-EVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEE 249
            T ELL E     + ++ K ++++    +L  Q+D  +E    L + ++    +L   +++
Sbjct: 1327 TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK 1386

Query: 250  VVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVL 309
            +  F   +EA  E    GK R Q  IENL Q+ E  EK   Y + ++    ++     ++
Sbjct: 1387 LQDFASTVEALEE----GKKRFQKEIENLTQQYE--EKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 310  TDISSNRK----PKCLSRGHPHSVCNHPDLKAHF-HPKGRNHLKKAKDDRASMQPAKAIH 364
             D+ + R+     +   R     +    ++ + +   + R   +  + +  ++  A+A+ 
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500

Query: 365  EQAESSRDLCRPPK 378
            E  E+  +L R  K
Sbjct: 1501 EALEAKEELERTNK 1514



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 50/227 (22%), Positives = 90/227 (39%), Gaps = 48/227 (21%)

Query: 154  KASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAE--------------LLEVRA 199
            K   E  V +  N  +    + +E+RI  LT  LA++  +              + E+  
Sbjct: 989  KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1048

Query: 200  AFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEA 259
               +  + +QE+++ +R L        E IA L+ ++ E + +L +KEEE       L+A
Sbjct: 1049 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE-------LQA 1101

Query: 260  AAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPK 319
            A        ARL D         E+A+K     + ++  G + DL   + ++ ++  K +
Sbjct: 1102 AL-------ARLDD---------EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145

Query: 320  CLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQ 366
               R          DL        +  L+   D  A+ Q  +A  EQ
Sbjct: 1146 KQKR----------DLGEELEAL-KTELEDTLDSTATQQELRAKREQ 1181



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 48/229 (20%), Positives = 97/229 (42%), Gaps = 34/229 (14%)

Query: 151  SDTKASFEAHVREKFNR---MVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQK 207
            +D +   EA  REK  +   +  A++  +E + ++L +      AE+ ++ ++   + + 
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKN 1533

Query: 208  KQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQG 267
              E+++ +RAL  Q++     +  L   L  +E+  LR E  +      L+   E+++Q 
Sbjct: 1534 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM----QALKGQFERDLQA 1589

Query: 268  KARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPH 327
            +    +     LQR      QL  Y+                T++   RK + L+     
Sbjct: 1590 RDEQNEEKRRQLQR------QLHEYE----------------TELEDERKQRALAAAAKK 1627

Query: 328  SV---CNHPDLKAHFHPKGRNH-LKKAKDDRASMQPAKAIHEQAESSRD 372
             +       +L+A    KGR   +K+ +  +A M+  +   E A +SRD
Sbjct: 1628 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1676



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 12/108 (11%)

Query: 184 TKELAQKTA-ELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEE 242
           TKE  QK   EL E+     QLT++K  +Q + +A       A EM    R RL   ++E
Sbjct: 871 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM----RVRLAAKKQE 926

Query: 243 LLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLE 290
           L    EE++   H +EA  E+E     +LQ   + + Q++   E+QLE
Sbjct: 927 L----EEIL---HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 29/122 (23%), Positives = 63/122 (51%), Gaps = 12/122 (9%)

Query: 178  KRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLT 237
            K+I +L   ++    +L   RAA  +  ++K+++     AL  +++  ++         T
Sbjct: 1118 KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS--------T 1169

Query: 238  ESEEELLRKEEEVVTFNHFLEAAAEKEVQG-KARLQDFIENLLQRVELAEKQLEYYQSQQ 296
             +++EL  K E+ VT    L+ A ++E +  +A++Q+  +   Q VE   +QLE ++  +
Sbjct: 1170 ATQQELRAKREQEVT---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 297  AS 298
            A+
Sbjct: 1227 AN 1228


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/254 (21%), Positives = 111/254 (43%), Gaps = 17/254 (6%)

Query: 133  DLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIE--KRIDKLTKELAQK 190
            +L +   DG R+   L  +D     +  V      + EA  + I+  K +  L+ +L Q 
Sbjct: 1263 ELQSKCSDGERARAEL--NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL-QD 1319

Query: 191  TAELL-EVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEE 249
            T ELL E     + ++ K ++++    +L  Q+D  +E    L + ++    +L   +++
Sbjct: 1320 TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK 1379

Query: 250  VVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVL 309
            +  F   +EA  E    GK R Q  IENL Q+ E  EK   Y + ++    ++     ++
Sbjct: 1380 LQDFASTVEALEE----GKKRFQKEIENLTQQYE--EKAAAYDKLEKTKNRLQQELDDLV 1433

Query: 310  TDISSNRK----PKCLSRGHPHSVCNHPDLKAHF-HPKGRNHLKKAKDDRASMQPAKAIH 364
             D+ + R+     +   R     +    ++ + +   + R   +  + +  ++  A+A+ 
Sbjct: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493

Query: 365  EQAESSRDLCRPPK 378
            E  E+  +L R  K
Sbjct: 1494 EALEAKEELERTNK 1507



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 50/227 (22%), Positives = 90/227 (39%), Gaps = 48/227 (21%)

Query: 154  KASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAE--------------LLEVRA 199
            K   E  V +  N  +    + +E+RI  LT  LA++  +              + E+  
Sbjct: 982  KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1041

Query: 200  AFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEA 259
               +  + +QE+++ +R L        E IA L+ ++ E + +L +KEEE       L+A
Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEE-------LQA 1094

Query: 260  AAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPK 319
            A        ARL D         E+A+K     + ++  G + DL   + ++ ++  K +
Sbjct: 1095 AL-------ARLDD---------EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138

Query: 320  CLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQ 366
               R          DL        +  L+   D  A+ Q  +A  EQ
Sbjct: 1139 KQKR----------DLGEELEAL-KTELEDTLDSTATQQELRAKREQ 1174



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 48/229 (20%), Positives = 97/229 (42%), Gaps = 34/229 (14%)

Query: 151  SDTKASFEAHVREKFNR---MVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQK 207
            +D +   EA  REK  +   +  A++  +E + ++L +      AE+ ++ ++   + + 
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKN 1526

Query: 208  KQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQG 267
              E+++ +RAL  Q++     +  L   L  +E+  LR E  +      L+   E+++Q 
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM----QALKGQFERDLQA 1582

Query: 268  KARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPH 327
            +    +     LQR      QL  Y+                T++   RK + L+     
Sbjct: 1583 RDEQNEEKRRQLQR------QLHEYE----------------TELEDERKQRALAAAAKK 1620

Query: 328  SV---CNHPDLKAHFHPKGRNH-LKKAKDDRASMQPAKAIHEQAESSRD 372
             +       +L+A    KGR   +K+ +  +A M+  +   E A +SRD
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1669



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 12/108 (11%)

Query: 184 TKELAQKTA-ELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEE 242
           TKE  QK   EL E+     QLT++K  +Q + +A       A EM    R RL   ++E
Sbjct: 864 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM----RVRLAAKKQE 919

Query: 243 LLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLE 290
           L    EE++   H +EA  E+E     +LQ   + + Q++   E+QLE
Sbjct: 920 L----EEIL---HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 29/122 (23%), Positives = 63/122 (51%), Gaps = 12/122 (9%)

Query: 178  KRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLT 237
            K+I +L   ++    +L   RAA  +  ++K+++     AL  +++  ++         T
Sbjct: 1111 KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS--------T 1162

Query: 238  ESEEELLRKEEEVVTFNHFLEAAAEKEVQG-KARLQDFIENLLQRVELAEKQLEYYQSQQ 296
             +++EL  K E+ VT    L+ A ++E +  +A++Q+  +   Q VE   +QLE ++  +
Sbjct: 1163 ATQQELRAKREQEVT---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219

Query: 297  AS 298
            A+
Sbjct: 1220 AN 1221


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 30/139 (21%), Positives = 64/139 (46%), Gaps = 9/139 (6%)

Query: 166 NRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVA 225
           N+M+  ++R  E+R+ +  + L ++   L E      +  ++  E + R R    ++   
Sbjct: 187 NQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQ 246

Query: 226 VEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELA 285
            E +    +RL E EE L  +EE +           ++++ G+ RL + +E LL++    
Sbjct: 247 EERLHEQEERLCEQEERLCEQEERL---------CEQEKLPGQERLLEEVEKLLEQERRQ 297

Query: 286 EKQLEYYQSQQASGFVRDL 304
           E+Q    + ++    V +L
Sbjct: 298 EEQERLLERERLLDEVEEL 316



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 34/162 (20%), Positives = 64/162 (39%), Gaps = 12/162 (7%)

Query: 150 TSDTKASFEAHVREKFNR-MVEAVDRTIE----------KRIDKLTKELAQKTAELLEVR 198
           TS  +   E H+ +K  R + +  ++T E           ++++L  E      EL  V 
Sbjct: 118 TSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVG 177

Query: 199 AAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLE 258
                  +  Q +    R    ++    E +    +RL E EE L  +EE +      L 
Sbjct: 178 RQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLR 237

Query: 259 AAAEKEVQGKARLQDFIENLLQRVE-LAEKQLEYYQSQQASG 299
              E+  + + RL +  E L ++ E L E++    + ++  G
Sbjct: 238 EQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPG 279



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 35/159 (22%), Positives = 67/159 (42%), Gaps = 17/159 (10%)

Query: 152 DTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTK------ELAQKTAELLEVR-----AA 200
           D+ ++  + + E  N +V       +  I  + K      +L  +TAE L        + 
Sbjct: 99  DSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSK 158

Query: 201 FVQLTQKKQEVQRRERALNRQVDVAVE---MIAVLRQRLTESEEELLRKEEEVVTFNHFL 257
             QL  +   +++   ++ RQ+   VE   M+++L +R    EE L  +EE +      L
Sbjct: 159 VEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR---QEERLREQEERLHEQEERL 215

Query: 258 EAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQ 296
               E+  + + RL +  E L ++ E   +Q E    Q+
Sbjct: 216 HEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQE 254


>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
          Length = 245

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/147 (25%), Positives = 68/147 (46%), Gaps = 8/147 (5%)

Query: 174 RTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLR 233
           + IE R  K  +++  +  +L E +       +K +EV R+   +   ++ A E   +  
Sbjct: 92  KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE 151

Query: 234 QRLTESEEELLRKEEEVVTFN-HFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYY 292
            +  E EEEL     + VT N   LEA AEK  Q + R ++ I+ L  +++ AE + E+ 
Sbjct: 152 GKCAELEEEL-----KTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 206

Query: 293 QSQ--QASGFVRDLSGHVLTDISSNRK 317
           +    +    + DL   +   +  NR+
Sbjct: 207 ERSVTKLEKSIDDLEDQLYQQLEQNRR 233



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 33/151 (21%)

Query: 155 ASFEAHVREKFNRMVEAVDRTIEKRIDKLTKEL--AQKTAELLEVRAAFVQLTQKKQEVQ 212
           +S EA VR K   + E  D   E+R   L +EL   +K  E  E   A          + 
Sbjct: 5   SSLEA-VRRKIRSLQEQADAA-EERAGTLQRELDHERKLRETAEADVA---------SLN 53

Query: 213 RRERALNRQVDVAVEMIAVLRQRLTESE-------------EELLRKEEEVVTFNHF--- 256
           RR + +  ++D A E +A   Q+L E+E             E   +K+EE +        
Sbjct: 54  RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 113

Query: 257 ----LEAAAEKEVQGKARLQDFIENLLQRVE 283
               +   A+++ +  AR    IE+ L+R E
Sbjct: 114 EAKHIAEDADRKYEEVARKLVIIESDLERAE 144


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 39/161 (24%), Positives = 76/161 (47%), Gaps = 14/161 (8%)

Query: 139  LDGTRSGPGLPTSDTKASFEAH-VREKFNRMVEAVDRTIEKRI-------DKLTKELAQK 190
            +DG      L   +T+   ++H V+ K    +EA    +E ++        KL KE+ + 
Sbjct: 1890 MDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRL 1949

Query: 191  TAELLEVRAAFVQ---LTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKE 247
              +L  +R    Q   + +K+ + +R E+    Q D+ ++  + L+Q + E   +L +KE
Sbjct: 1950 QKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKE 2009

Query: 248  EEV-VTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEK 287
            +E+ +T    +  A E E +     Q+    LL+++  AEK
Sbjct: 2010 QELEMTIKETINKAQEVEAELLESHQEETNQLLKKI--AEK 2048



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 33/144 (22%), Positives = 71/144 (49%), Gaps = 15/144 (10%)

Query: 170 EAVDRTIEKRIDKLTK----ELAQKTAELLEVRAAFVQLTQKKQE----VQRRERALNRQ 221
           EA+   +++R+ +L K     +A+KT  + ++R A   + Q +Q+    +   +R ++  
Sbjct: 317 EALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHET 376

Query: 222 VDVAVEMIAVLRQR---LTESEEELLRKEE--EVVTFNHFLEA--AAEKEVQGKARLQDF 274
           +++  E IA LR R   +T   EEL  ++E  E   F    +A   A+K  + + +L+  
Sbjct: 377 LEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAE 436

Query: 275 IENLLQRVELAEKQLEYYQSQQAS 298
           ++  ++ +E   ++      Q+ S
Sbjct: 437 MDEQIKTIEKTSEEERISLQQELS 460



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/128 (21%), Positives = 66/128 (51%), Gaps = 4/128 (3%)

Query: 185 KELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELL 244
           ++LAQ   +LL++    + LT++  EV+ +++ +  ++D     +  L Q+L +   E+ 
Sbjct: 819 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEME 878

Query: 245 RKEEEVV-TFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRD 303
           +K + +   +   LE   +++ Q K  L +    +LQ  E  +K++E    + ++   ++
Sbjct: 879 QKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA---KE 935

Query: 304 LSGHVLTD 311
            S H+L +
Sbjct: 936 DSIHILNE 943



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 24/105 (22%), Positives = 53/105 (50%), Gaps = 10/105 (9%)

Query: 178 KRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLT 237
           +R+ ++ + L+    +  E+  A+  L ++K+++Q     L++  D ++  IA LR+ L 
Sbjct: 141 QRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQG---ILSQSQDKSLRRIAELREELQ 197

Query: 238 ESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRV 282
             ++     +EE        +A+ E++ Q  + LQ  +  L QR+
Sbjct: 198 MDQQAKKHLQEE-------FDASLEEKDQYISVLQTQVSLLKQRL 235


>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
          Length = 1068

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 15/156 (9%)

Query: 159 AHVREKFNRMVEAVDRTIEKRID-------KLTKELAQKTAELLEVRAAFVQLTQKKQEV 211
           A V+E+    VE V R  E +++       KL +EL  K  EL   + A     Q K E+
Sbjct: 486 ARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSEL 545

Query: 212 QRRERALNRQVDVAVEMIAVLRQRLTE--SEEELLRKEEEVVTFNHFLEAAAEKEVQGKA 269
             R   L+ + D    +   +RQR  +  + + L+R+ E  ++      +  + E+QG+ 
Sbjct: 546 SSRLDTLSAEKDA---LSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQGRL 602

Query: 270 RLQDFIENLLQRVELAEKQLEYYQ--SQQASGFVRD 303
             ++  E  L R  L ++Q    +  + +A+G ++D
Sbjct: 603 AERESQEQGL-RQRLLDEQFAVLRGAAAEAAGILQD 637


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 58/247 (23%), Positives = 103/247 (41%), Gaps = 15/247 (6%)

Query: 44  RAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYS 103
           +A+L+  H  +E +LL +       + +++V     L  G   SS +++  +  Y  L  
Sbjct: 735 KANLKIDHLEKETSLLRQS------EGSNVVFKGIDLPDGIAPSSASIINSQNEY--LIH 786

Query: 104 ISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVRE 163
           +  E     K  + + +    Y + + A+  H  SL          T  T++      + 
Sbjct: 787 LLQELENKEKKLKNLEDSLEDYNRKF-AVIRHQQSLLYKEYLSEKETWKTESKTIKEEKR 845

Query: 164 KFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVD 223
           K    V+  D    K  + L   L   + E+ ++ A   + ++K   +Q  E++L RQ  
Sbjct: 846 KLEDQVQQ-DAIKVKEYNNLLNALQMDSDEMKKILA---ENSRKITVLQVNEKSLIRQYT 901

Query: 224 VAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIEN--LLQR 281
             VE+   LR+   + + ELL  E EV      L+   E  +   A LQ  ++N   L  
Sbjct: 902 TLVELERQLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSE 961

Query: 282 VELAEKQ 288
           +ELA KQ
Sbjct: 962 LELANKQ 968



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 35/164 (21%), Positives = 71/164 (43%), Gaps = 19/164 (11%)

Query: 90   NVVKQKPSYVNLYSISHEHSKDRKP-FEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGL 148
            +   QK +++N+  I   H+++ K   E + E  +   +         +SL    +    
Sbjct: 1765 SATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNN 1824

Query: 149  PTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKK 208
                 + ++   +REK    ++  +  ++++I +LT  L  K             LT  K
Sbjct: 1825 ELQKKQKAYNKILREK--EEIDQENDELKRQIKRLTSGLQGKP------------LTDNK 1870

Query: 209  Q----EVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEE 248
            Q    E+QR+ + L  Q++  VE + +   +   ++EEL+R EE
Sbjct: 1871 QSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEE 1914



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 27/143 (18%), Positives = 58/143 (40%), Gaps = 21/143 (14%)

Query: 176 IEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNR--------------- 220
           +EK++++  +EL     EL + +    QL  + +E +     L R               
Sbjct: 120 LEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQD 179

Query: 221 ------QVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDF 274
                 Q+D   E +   R   ++   +L +K  E++ +   ++   E   + + + Q+ 
Sbjct: 180 IIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEM 239

Query: 275 IENLLQRVELAEKQLEYYQSQQA 297
            +NL + V+  EK  + Y   +A
Sbjct: 240 RKNLEESVQEMEKMTDEYNRMKA 262



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 14/139 (10%)

Query: 173  DRTIEKRIDKLTKELAQKTAELLEVRAA--FVQLTQKKQEVQRRERALNRQVDVAVEMIA 230
            ++T+E  +    K L +  + L + + A   +    K +E++ +E  LNR++    E I 
Sbjct: 1316 NKTLEMELK--LKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKDKEEIK 1373

Query: 231  VLRQRLTESEEELLRKEEEVVTFNHFLE----AAAEKEVQGKARLQDFIENLLQRVELAE 286
             L   ++E E  +   EEE+V  N F E    A  ++EV  + +L  F     + +  A+
Sbjct: 1374 YLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQ 1433

Query: 287  KQLEYYQSQQASGFVRDLS 305
            K       ++A+G + D S
Sbjct: 1434 K------FEEATGSIPDPS 1446



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 32/137 (23%), Positives = 61/137 (44%), Gaps = 14/137 (10%)

Query: 148  LPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQK 207
            L T  T  S E  ++EK + +  A    + +  DK+  EL  +     E      +L +K
Sbjct: 1468 LETRATCKSLEEKLKEKESALRLAEQNILSR--DKVINELRLRLPATAEREKLIAELGRK 1525

Query: 208  KQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQG 267
            + E +      +  + +A + IA ++ RL + EE L +       +   LE A E++ + 
Sbjct: 1526 EMEPKS-----HHTLKIAHQTIANMQARLNQKEEVLKK-------YQRLLEKAREEQREI 1573

Query: 268  KARLQDFIENLLQRVEL 284
              + ++ +  L  R+EL
Sbjct: 1574 VKKHEEDLHILHHRLEL 1590


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,100,028
Number of Sequences: 37866
Number of extensions: 665908
Number of successful extensions: 4798
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 413
Number of HSP's that attempted gapping in prelim test: 3492
Number of HSP's gapped (non-prelim): 1455
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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