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Search of human proteins with 148596968
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148596968 tripartite motif-containing 8 [Homo sapiens]
(551 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148596968 tripartite motif-containing 8 [Homo sapiens] 1155 0.0
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 126 5e-29
gi|223890259 midline 2 isoform 2 [Homo sapiens] 105 8e-23
gi|223890257 midline 2 isoform 1 [Homo sapiens] 105 8e-23
gi|148833499 midline 1 [Homo sapiens] 97 3e-20
gi|4557753 midline 1 [Homo sapiens] 97 3e-20
gi|15451852 midline 1 [Homo sapiens] 97 3e-20
gi|54792146 tripartite motif-containing 47 [Homo sapiens] 96 9e-20
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 95 1e-19
gi|217035095 tripartite motif-containing 62 [Homo sapiens] 94 2e-19
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 91 4e-18
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-... 84 4e-16
gi|62865604 tripartite motif protein 31 [Homo sapiens] 82 1e-15
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 82 1e-15
gi|239755488 PREDICTED: similar to ring finger protein 18 isofor... 82 1e-15
gi|210147600 tripartite motif-containing 64 [Homo sapiens] 81 2e-15
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 81 3e-15
gi|5730009 ret finger protein [Homo sapiens] 80 5e-15
gi|169202726 PREDICTED: similar to ring finger protein 18 isofor... 80 6e-15
gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo ... 80 6e-15
gi|27484954 PREDICTED: similar to ring finger protein 18 [Homo s... 80 6e-15
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 80 6e-15
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 79 8e-15
gi|30023818 tripartite motif protein 50A [Homo sapiens] 79 8e-15
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li... 78 2e-14
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 76 7e-14
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 76 7e-14
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 76 7e-14
gi|169202730 PREDICTED: similar to hCG1802386 [Homo sapiens] 75 2e-13
gi|89034675 PREDICTED: similar to hCG1802386 [Homo sapiens] 75 2e-13
>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
Length = 551
Score = 1155 bits (2987), Expect = 0.0
Identities = 551/551 (100%), Positives = 551/551 (100%)
Query: 1 MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYN 60
MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYN
Sbjct: 1 MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYN 60
Query: 61 QKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQ 120
QKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQ
Sbjct: 61 QKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQ 120
Query: 121 THLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVC 180
THLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVC
Sbjct: 121 THLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVC 180
Query: 181 DVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLH 240
DVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLH
Sbjct: 181 DVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLH 240
Query: 241 QLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMK 300
QLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMK
Sbjct: 241 QLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMK 300
Query: 301 NTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQ 360
NTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQ
Sbjct: 301 NTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQ 360
Query: 361 SVPLYPCGVSSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASGEGQSGQPLGPCS 420
SVPLYPCGVSSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASGEGQSGQPLGPCS
Sbjct: 361 SVPLYPCGVSSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASGEGQSGQPLGPCS 420
Query: 421 STQHLVALPGGAQPVHSSPVFPPSQYPNGSAAQQPMLPQYGGRKILVCSVDNCYCSSVAN 480
STQHLVALPGGAQPVHSSPVFPPSQYPNGSAAQQPMLPQYGGRKILVCSVDNCYCSSVAN
Sbjct: 421 STQHLVALPGGAQPVHSSPVFPPSQYPNGSAAQQPMLPQYGGRKILVCSVDNCYCSSVAN 480
Query: 481 HGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPSLAVRDWLDASQQPGHQDFYRVY 540
HGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPSLAVRDWLDASQQPGHQDFYRVY
Sbjct: 481 HGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSVPQSLPSLAVRDWLDASQQPGHQDFYRVY 540
Query: 541 GQPSTKHYVTS 551
GQPSTKHYVTS
Sbjct: 541 GQPSTKHYVTS 551
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 126 bits (317), Expect = 5e-29
Identities = 85/314 (27%), Positives = 129/314 (41%), Gaps = 25/314 (7%)
Query: 11 EELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLK 70
EEL C ICL F EPV PC HNFC C+ E WA CP+C Y +P L KN
Sbjct: 9 EELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTV 68
Query: 71 LTNIVEKF-NALHVEKPPAALHCVFCRRGPPLP-------------AQKVCLRCEAPCCQ 116
L N+VE+F A +PPA + R P P A K CL C A CQ
Sbjct: 69 LCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQ 128
Query: 117 SHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCY----YSG 172
H+Q H P+ L D+ C QHN R + C +C C S
Sbjct: 129 EHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSP 188
Query: 173 AHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEV 232
A + D+E +R L ++ + ++D + + + KV QL++E
Sbjct: 189 ASLSQASADLEA---TLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQE- 244
Query: 233 RLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDK 292
Y ++ LLD + + + + + S+ L ++ E + L ++ K
Sbjct: 245 ---YTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTK 301
Query: 293 TEDVSFMKNTKSVK 306
++ F++ ++
Sbjct: 302 RDEFEFLEKASKLR 315
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 105 bits (263), Expect = 8e-23
Identities = 87/380 (22%), Positives = 159/380 (41%), Gaps = 48/380 (12%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCI----------GEAWAKDSGLVRCPECNQA- 58
E EL CPICL +F +P+ LPC H+ C C GE+ + +CP C
Sbjct: 25 ESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGES-IEPITAFQCPTCRYVI 83
Query: 59 ---YNQKPGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCR 96
+ GL++N+ L NI+++F V P + + C FC
Sbjct: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
Query: 97 RGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL 153
+ PP A K C+ CE C ++ H LVE +R +C H ++
Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
Query: 154 -YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLY 212
+C ++ +C C G H+ H V + R ++++ L L +R ++E+Q+
Sbjct: 204 NMYCVSDDQLICA-LCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMA 262
Query: 213 KLESDKRLVEEKVNQLKEEVRLQYE--KLHQLLDEDLRQTVEVLDKAQAKFCSENAAQAL 270
KL + VE VN E +L E +L +++ + + + + + + A Q
Sbjct: 263 KLIQICQQVE--VNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
Query: 271 HLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNS 330
+ + ++ + L+ + + + + F+++ K++ +R T+S S I +N
Sbjct: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNI---AERVAMATAS--SQVLIPDINF 375
Query: 331 KLFLNEVAKKEKQLRKMLEG 350
A + +K+LEG
Sbjct: 376 NDAFENFALDFSREKKLLEG 395
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 105 bits (263), Expect = 8e-23
Identities = 87/380 (22%), Positives = 159/380 (41%), Gaps = 48/380 (12%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCI----------GEAWAKDSGLVRCPECNQA- 58
E EL CPICL +F +P+ LPC H+ C C GE+ + +CP C
Sbjct: 25 ESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGES-IEPITAFQCPTCRYVI 83
Query: 59 ---YNQKPGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCR 96
+ GL++N+ L NI+++F V P + + C FC
Sbjct: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
Query: 97 RGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL 153
+ PP A K C+ CE C ++ H LVE +R +C H ++
Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
Query: 154 -YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLY 212
+C ++ +C C G H+ H V + R ++++ L L +R ++E+Q+
Sbjct: 204 NMYCVSDDQLICA-LCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMA 262
Query: 213 KLESDKRLVEEKVNQLKEEVRLQYE--KLHQLLDEDLRQTVEVLDKAQAKFCSENAAQAL 270
KL + VE VN E +L E +L +++ + + + + + + A Q
Sbjct: 263 KLIQICQQVE--VNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
Query: 271 HLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNS 330
+ + ++ + L+ + + + + F+++ K++ +R T+S S I +N
Sbjct: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNI---AERVAMATAS--SQVLIPDINF 375
Query: 331 KLFLNEVAKKEKQLRKMLEG 350
A + +K+LEG
Sbjct: 376 NDAFENFALDFSREKKLLEG 395
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 97.4 bits (241), Expect = 3e-20
Identities = 81/350 (23%), Positives = 145/350 (41%), Gaps = 48/350 (13%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGC-----IGEAWAKDS----GLVRCPECNQAYN 60
E EL CPICL +F +P+ LPC H+ C C + +S +CP C
Sbjct: 5 ESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVIT 64
Query: 61 QK----PGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCRR 97
GL++N+ L NI+++F V P + + C FC +
Sbjct: 65 LSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQ 124
Query: 98 GPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL- 153
P A K C+ CE C ++ GH L+E +R C +H ++
Sbjct: 125 DPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVN 184
Query: 154 YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYK 213
+C + +C C G H+ H V + R +++++ L L +R ++E L K
Sbjct: 185 MYCVTDDQLICA-LCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243
Query: 214 LESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEV----LDKAQAKFCSENAAQA 269
L + VE VN ++E +L E LL E ++Q ++ + + + + A Q
Sbjct: 244 LIQTCQHVE--VNASRQEAKLTEE--CDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQI 299
Query: 270 LHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSS 319
+ + ++ + L+ + + + F++ K++ +R T+SS
Sbjct: 300 ANCKQCIERSASLISQAEHSLKENDHARFLQTAKNI---TERVSMATASS 346
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 97.4 bits (241), Expect = 3e-20
Identities = 81/350 (23%), Positives = 145/350 (41%), Gaps = 48/350 (13%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGC-----IGEAWAKDS----GLVRCPECNQAYN 60
E EL CPICL +F +P+ LPC H+ C C + +S +CP C
Sbjct: 5 ESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVIT 64
Query: 61 QK----PGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCRR 97
GL++N+ L NI+++F V P + + C FC +
Sbjct: 65 LSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQ 124
Query: 98 GPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL- 153
P A K C+ CE C ++ GH L+E +R C +H ++
Sbjct: 125 DPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVN 184
Query: 154 YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYK 213
+C + +C C G H+ H V + R +++++ L L +R ++E L K
Sbjct: 185 MYCVTDDQLICA-LCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243
Query: 214 LESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEV----LDKAQAKFCSENAAQA 269
L + VE VN ++E +L E LL E ++Q ++ + + + + A Q
Sbjct: 244 LIQTCQHVE--VNASRQEAKLTEE--CDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQI 299
Query: 270 LHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSS 319
+ + ++ + L+ + + + F++ K++ +R T+SS
Sbjct: 300 ANCKQCIERSASLISQAEHSLKENDHARFLQTAKNI---TERVSMATASS 346
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 97.4 bits (241), Expect = 3e-20
Identities = 81/350 (23%), Positives = 145/350 (41%), Gaps = 48/350 (13%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGC-----IGEAWAKDS----GLVRCPECNQAYN 60
E EL CPICL +F +P+ LPC H+ C C + +S +CP C
Sbjct: 5 ESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVIT 64
Query: 61 QK----PGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCRR 97
GL++N+ L NI+++F V P + + C FC +
Sbjct: 65 LSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQ 124
Query: 98 GPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL- 153
P A K C+ CE C ++ GH L+E +R C +H ++
Sbjct: 125 DPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVN 184
Query: 154 YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYK 213
+C + +C C G H+ H V + R +++++ L L +R ++E L K
Sbjct: 185 MYCVTDDQLICA-LCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243
Query: 214 LESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEV----LDKAQAKFCSENAAQA 269
L + VE VN ++E +L E LL E ++Q ++ + + + + A Q
Sbjct: 244 LIQTCQHVE--VNASRQEAKLTEE--CDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQI 299
Query: 270 LHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSS 319
+ + ++ + L+ + + + F++ K++ +R T+SS
Sbjct: 300 ANCKQCIERSASLISQAEHSLKENDHARFLQTAKNI---TERVSMATASS 346
>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
Length = 638
Score = 95.9 bits (237), Expect = 9e-20
Identities = 69/236 (29%), Positives = 99/236 (41%), Gaps = 51/236 (21%)
Query: 15 CPICLHVFVEPVQLPCKHNFCRGCIGEAW--------AKDSGLVRCPECNQAYNQKPGLE 66
CPICL EPV LPC HNFC C+G W G RCP C + + L
Sbjct: 9 CPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQLR 68
Query: 67 KNLKLTNIVE----------------------KFNALHVEKPPAA-------------LH 91
KN L+ +++ +AL P+A +
Sbjct: 69 KNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVR 128
Query: 92 CVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLV-EADDVRAWSCPQHNA 150
C C G LPA CL C A C +H+ H + P+ RGH LV + CP+H
Sbjct: 129 CDACPEGAALPAALSCLSCLASFCPAHLGPHERSPA-LRGHRLVPPLRRLEESLCPRHLR 187
Query: 151 YRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVE----IRRNEIRKMLMKQQDRLEE 202
+C AE+V +C+ C + H+GH + +E ++ E K+L +DR++E
Sbjct: 188 PLERYCRAERVCLCEACA--AQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDE 241
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 95.1 bits (235), Expect = 1e-19
Identities = 84/362 (23%), Positives = 140/362 (38%), Gaps = 61/362 (16%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGE---------------------------- 41
E ELICP C +F P+ LPC+H+ C C+ E
Sbjct: 28 ERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPS 87
Query: 42 ------------AWAKDSGLVR-----CPECNQAYNQKP----GLEKNLKLTNIVEKFNA 80
W ++S R CP C + GL +N L IVE++
Sbjct: 88 PSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYR- 146
Query: 81 LHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADD- 139
+ A+ C C+ PP + K C+ C A C + H + H V
Sbjct: 147 -QAARAATAIMCDLCKP-PPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGPTTN 204
Query: 140 --VRAWSCPQHNAYRL-YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQ 196
+ CP+H R+ +CE + VC + C G H H V + +++ L K
Sbjct: 205 FRPKILMCPEHETERINMYCELCRRPVC-HLCKLGGNHANHRVTTMSSAYKTLKEKLSKD 263
Query: 197 QDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEVLDK 256
D L +E ++ Q+ +L + E + KEE +EKL ++L+E ++ +D
Sbjct: 264 IDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDS 323
Query: 257 AQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCT 316
++ K + + + + E L+G Q + +T+ F++ K + + R Q T
Sbjct: 324 SK-KLRLDKFQTQMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHL---RIQKAT 379
Query: 317 SS 318
S
Sbjct: 380 ES 381
>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
Length = 475
Score = 94.4 bits (233), Expect = 2e-19
Identities = 69/298 (23%), Positives = 129/298 (43%), Gaps = 54/298 (18%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKD--SGLVRCPECNQAYNQKPGLEK 67
++EL+C ICL ++ +PV L C+H FCR CI E W + G CPEC + + +P L
Sbjct: 6 KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTF-AEPALAP 64
Query: 68 NLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPS 127
+LKL NIVE++++ PL A R P CQ+H + L
Sbjct: 65 SLKLANIVERYSSF------------------PLDAILNARRAARP-CQAHDKVKL---- 101
Query: 128 TARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRN 187
C ++ +C + C H+ H V ++ +
Sbjct: 102 ---------------------------FCLTDRALLC-FFCDEPALHEQHQVTGIDDAFD 133
Query: 188 EIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDL 247
E+++ L Q L++ E++ + L L+ + L+ + +E+LH+LL E
Sbjct: 134 ELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQ 193
Query: 248 RQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSV 305
+ +E L+ A+ ++ + +++++ ++ LQ +T+ +F+ S+
Sbjct: 194 KAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASL 251
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 90.5 bits (223), Expect = 4e-18
Identities = 69/280 (24%), Positives = 110/280 (39%), Gaps = 59/280 (21%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNL 69
+EE C ICL F +PV C HNFCR CI W + G CPEC + Q+ L N
Sbjct: 11 QEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQR-NLRPNR 69
Query: 70 KLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTA 129
L + E LH PP P
Sbjct: 70 PLAKMAEMARRLH----------------PPSP--------------------------- 86
Query: 130 RGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEI 189
V CP H C E +C C SG H H V ++ ++
Sbjct: 87 ----------VPQGVCPAHREPLAAFCGDELRLLCA-ACERSGEHWAHRVRPLQDAAEDL 135
Query: 190 RKMLMKQQDRLEEREQDIEDQLYKLESDKRLV--EEKVNQLKEEVRLQYEKLHQLLDEDL 247
+ L K + L ++ QD L++ ++D+ V ++ V ++ V ++E+L +LL E+
Sbjct: 136 KAKLEKSLEHLRKQMQDA--LLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEE 193
Query: 248 RQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQ 287
+Q ++ L++ + + A HLG++ +L+ L+
Sbjct: 194 QQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELE 233
>gi|169202375 PREDICTED: tripartite motif-containing protein
64B-like [Homo sapiens]
Length = 449
Score = 83.6 bits (205), Expect = 4e-16
Identities = 66/314 (21%), Positives = 131/314 (41%), Gaps = 55/314 (17%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELIC IC++ F++PV + C H+FCR C+ + +RCP C + ++KP N
Sbjct: 9 FQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKT-SEKPNFNTN 67
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
L +++K ++L + P ++
Sbjct: 68 L----VLKKLSSLARQTRPQNIN------------------------------------- 86
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
+D++ C H + CEA++ +C C S H HS + E
Sbjct: 87 -------SSDNI----CVLHEETKELFCEADKRLLCGPCS-ESPEHMAHSHSPIGWAAEE 134
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
R+ L+K+ D L E Q+ + L + S +++ V+ K + +QY+K+ LDE+ +
Sbjct: 135 CREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQ 194
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKIL 308
+ ++ L++ + + + + + ++ K + L DV +++ ++V
Sbjct: 195 RHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETC-HMPDVVLLQDVRNVSAR 253
Query: 309 MDRTQTCTSSSLSP 322
D Q ++P
Sbjct: 254 TDLAQMQKPQPVNP 267
>gi|62865604 tripartite motif protein 31 [Homo sapiens]
Length = 425
Score = 82.4 bits (202), Expect = 1e-15
Identities = 58/240 (24%), Positives = 99/240 (41%), Gaps = 52/240 (21%)
Query: 7 NCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLE 66
N +EE+ICPICL + +PV + C HNFC CI + G +CP C + +K +
Sbjct: 8 NKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV-RKNAIR 66
Query: 67 KNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQP 126
N L N+VEK AL S VQ+ ++
Sbjct: 67 FNSLLRNLVEKIQALQA---------------------------------SEVQSKRKEA 93
Query: 127 STARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRR 186
+CP+H Y CE + +C + C S H+ H+V +E
Sbjct: 94 -----------------TCPRHQEMFHYFCEDDGKFLC-FVCRESKDHKSHNVSLIEEAA 135
Query: 187 NEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDED 246
+ + +Q L+++E++ + + ++V K+ + ++E LHQ+L+E+
Sbjct: 136 QNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQRILTEFELLHQVLEEE 195
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 82.4 bits (202), Expect = 1e-15
Identities = 78/344 (22%), Positives = 135/344 (39%), Gaps = 73/344 (21%)
Query: 10 EEELICPICLHVFVEPVQ-LPCKHNFCRGCI--------------GEAWAKDSGLVRCPE 54
E++LICPICL +F +PV LPC+HN CR C G + + G RCP
Sbjct: 18 EKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRFRCPT 77
Query: 55 CNQAY----NQKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRC 110
C + GL++NL + NI++ + +P C+ CL C
Sbjct: 78 CRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHPMCKEHEDEKINIYCLTC 137
Query: 111 EAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYY 170
E P C C ++ CE +
Sbjct: 138 EVPTCS---------------------------MCKVFGIHKA--CEVAPL--------- 159
Query: 171 SGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKE 230
QG + N ML+ DR ++ + +LE +R+ +E +Q+KE
Sbjct: 160 QSVFQGQ-----KTELNNCISMLVAGNDR-------VQTIITQLEDSRRVTKENSHQVKE 207
Query: 231 EVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLF 290
E+ +++ L+ +LDE + ++ + + Q K S A E++ ++ KL+ +
Sbjct: 208 ELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSL 267
Query: 291 DKTEDVSFMKNTKS-VKILMDRTQTCTSSSLSPTKIGHLNSKLF 333
D+ +F+ K +K +++ ++ C L T+ G N F
Sbjct: 268 DEPGGATFLLTAKQLIKSIVEASKGC---QLGKTEQGFENMDFF 308
>gi|239755488 PREDICTED: similar to ring finger protein 18 isoform 2
[Homo sapiens]
Length = 446
Score = 82.0 bits (201), Expect = 1e-15
Identities = 74/302 (24%), Positives = 127/302 (42%), Gaps = 63/302 (20%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELICPIC++ F++PV + C H+FCR C W LV+C EC ++ Q N
Sbjct: 9 FQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTGQ-----IN 63
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
LK TNI H +K + A+KV L
Sbjct: 64 LK-TNI-------HFKKMASL-------------ARKVSL-------------------- 82
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
L + +++ C H + CE ++ +C C S H+ H C +E E
Sbjct: 83 ---WLFLSSEE---QMCGTHRETKKMFCEVDRSLLC-LLCSSSQEHRDHRHCPIESAAEE 135
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
++ L+++ L E+ + L + R ++ VN E +R +Y+K+ E+ +
Sbjct: 136 HQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEK 195
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKIL 308
+E+L K ++ LHL + K+ ++L E+++ M + V++L
Sbjct: 196 HNLEMLKKK-----GKDIFHRLHLSK-----AKMAHRREILRGMYEELNEMCHKPDVELL 245
Query: 309 MD 310
D
Sbjct: 246 QD 247
>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
Length = 449
Score = 81.3 bits (199), Expect = 2e-15
Identities = 64/314 (20%), Positives = 130/314 (41%), Gaps = 55/314 (17%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELIC IC++ F++PV + C H+FCR C+ + +RCP C + ++KP N
Sbjct: 9 FQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRK-ISEKPNFNTN 67
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
+ +++K ++L + P ++
Sbjct: 68 V----VLKKLSSLARQTRPQNIN------------------------------------- 86
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
+D++ C H + CEA++ +C C S H HS + E
Sbjct: 87 -------SSDNI----CVLHEETKELFCEADKRLLCGPCS-ESPEHMAHSHSPIGWAAEE 134
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
R+ L+K+ D L E Q+ + L + +++ V+ K + +QY+K+ LDE+ +
Sbjct: 135 CREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQ 194
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKIL 308
+ ++ L++ + + + + + ++ K + L DV +++ ++V
Sbjct: 195 RHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETC-HVPDVELLQDVRNVSAR 253
Query: 309 MDRTQTCTSSSLSP 322
D Q ++P
Sbjct: 254 TDLAQMQKPQPVNP 267
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 80.9 bits (198), Expect = 3e-15
Identities = 68/274 (24%), Positives = 103/274 (37%), Gaps = 56/274 (20%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNL 69
+EEL CPICL F +PV + C HNFCRGC+ WA G CPEC + L N
Sbjct: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHP-SAPAALRPNW 65
Query: 70 KLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTA 129
L + EK R GP P C H
Sbjct: 66 ALARLTEKTQRR--------------RLGPVPPG----------LCGRH----------- 90
Query: 130 RGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEI 189
W RL+ CE +Q VC C S HQ H++ ++
Sbjct: 91 -------------WE-----PLRLF-CEDDQRPVC-LVCRESQEHQTHAMAPIDEAFESY 130
Query: 190 RKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQ 249
R+ L+K Q L + + + + ++K+ + + ++ KLH L E+
Sbjct: 131 REKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDL 190
Query: 250 TVEVLDKAQAKFCSENAAQALHLGERMQEAKKLL 283
++ L+K + + + L L + + KKL+
Sbjct: 191 FLQRLNKEEEETKKKLNENTLKLNQTIASLKKLI 224
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 80.1 bits (196), Expect = 5e-15
Identities = 61/254 (24%), Positives = 100/254 (39%), Gaps = 56/254 (22%)
Query: 8 CFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEK 67
C ++E CP+CL F EP+ L C HN C C+ W V CP+C + + Q+ +
Sbjct: 9 CLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQR-HMRP 67
Query: 68 NLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPS 127
N L N+ + L E+ PS
Sbjct: 68 NRHLANVTQLVKQLRTER----------------------------------------PS 87
Query: 128 TARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRN 187
G + V C +H +CE +Q+ +C C S H+GHSV +E
Sbjct: 88 GPGGEMGV---------CEKHREPLKLYCEEDQMPIC-VVCDRSREHRGHSVLPLEEAVE 137
Query: 188 EIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQL-KEEVRLQYEKLHQLLDED 246
++ + Q D L +R +D++ + R + Q+ +E++ ++E+L+ L E
Sbjct: 138 GFKEQIQNQLDHL-KRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEH 196
Query: 247 ---LRQTVEVLDKA 257
L +E LD A
Sbjct: 197 EYRLLARLEELDLA 210
>gi|169202726 PREDICTED: similar to ring finger protein 18 isoform 1
[Homo sapiens]
Length = 452
Score = 79.7 bits (195), Expect = 6e-15
Identities = 73/300 (24%), Positives = 126/300 (42%), Gaps = 63/300 (21%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELICPIC++ F++PV + C H+FCR C W LV+C EC ++ Q N
Sbjct: 9 FQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTGQ-----IN 63
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
LK TNI H +K + A+KV L
Sbjct: 64 LK-TNI-------HFKKMASL-------------ARKVSL-------------------- 82
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
L + +++ C H + CE ++ +C C S H+ H C +E E
Sbjct: 83 ---WLFLSSEE---QMCGTHRETKKMFCEVDRSLLC-LLCSSSQEHRDHRHCPIESAAEE 135
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
++ L+++ L E+ + L + R ++ VN E +R +Y+K+ E+ +
Sbjct: 136 HQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEK 195
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKIL 308
+E+L K ++ LHL + K+ ++L E+++ M + V++L
Sbjct: 196 HNLEMLKKK-----GKDIFHRLHLSK-----AKMAHRREILRGMYEELNEMCHKPDVELL 245
>gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo
sapiens]
Length = 452
Score = 79.7 bits (195), Expect = 6e-15
Identities = 73/300 (24%), Positives = 126/300 (42%), Gaps = 63/300 (21%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELICPIC++ F++PV + C H+FCR C W LV+C EC ++ Q N
Sbjct: 9 FQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTGQ-----IN 63
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
LK TNI H +K + A+KV L
Sbjct: 64 LK-TNI-------HFKKMASL-------------ARKVSL-------------------- 82
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
L + +++ C H + CE ++ +C C S H+ H C +E E
Sbjct: 83 ---WLFLSSEE---QMCGTHRETKKMFCEVDRSLLC-LLCSSSQEHRDHRHCPIESAAEE 135
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
++ L+++ L E+ + L + R ++ VN E +R +Y+K+ E+ +
Sbjct: 136 HQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEK 195
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKIL 308
+E+L K ++ LHL + K+ ++L E+++ M + V++L
Sbjct: 196 HNLEMLKKK-----GKDIFHRLHLSK-----AKMAHRREILRGMYEELNEMCHKPDVELL 245
>gi|27484954 PREDICTED: similar to ring finger protein 18 [Homo
sapiens]
Length = 452
Score = 79.7 bits (195), Expect = 6e-15
Identities = 73/300 (24%), Positives = 126/300 (42%), Gaps = 63/300 (21%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELICPIC++ F++PV + C H+FCR C W LV+C EC ++ Q N
Sbjct: 9 FQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTGQ-----IN 63
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
LK TNI H +K + A+KV L
Sbjct: 64 LK-TNI-------HFKKMASL-------------ARKVSL-------------------- 82
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
L + +++ C H + CE ++ +C C S H+ H C +E E
Sbjct: 83 ---WLFLSSEE---QMCGTHRETKKMFCEVDRSLLC-LLCSSSQEHRDHRHCPIESAAEE 135
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
++ L+++ L E+ + L + R ++ VN E +R +Y+K+ E+ +
Sbjct: 136 HQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEK 195
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKIL 308
+E+L K ++ LHL + K+ ++L E+++ M + V++L
Sbjct: 196 HNLEMLKKK-----GKDIFHRLHLSK-----AKMAHRREILRGMYEELNEMCHKPDVELL 245
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 79.7 bits (195), Expect = 6e-15
Identities = 75/271 (27%), Positives = 117/271 (43%), Gaps = 39/271 (14%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNL 69
+EEL CPICL F +PV + C HNFCRGC+ WA G CPEC + L N
Sbjct: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHP-SAPAALRPNW 65
Query: 70 KLTNIVEKFNALHVEKPPAALHCVFC-RRGPPL------PAQKVCLRCEAPCCQSHVQTH 122
L + EK + P L C R PL + VCL C Q H QTH
Sbjct: 66 ALARLTEKTQRRRLGPVPPGL----CGRHWEPLRLFCEDDQRPVCLVCRE--SQEH-QTH 118
Query: 123 LQQP------STARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQG 176
P S G+ + D+ W + LYH + E+ + + +
Sbjct: 119 AMAPIDEAFESYRTGNFDIHVDE---WK-RRLIRLLLYHSKQEEKLLKSQRNLVAKMKKV 174
Query: 177 HSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLES----DKRLVEEKVNQLKEEV 232
+ DVE+ K + +D+++ + I + KL + ++ L +++N+ +EE
Sbjct: 175 MHLQDVEV------KNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEET 228
Query: 233 RLQYE----KLHQLLDEDLRQTVEVLDKAQA 259
+ + KL+Q + + +EV +K+QA
Sbjct: 229 KKKLNENTLKLNQTIASLKKLILEVGEKSQA 259
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 79.3 bits (194), Expect = 8e-15
Identities = 72/294 (24%), Positives = 116/294 (39%), Gaps = 66/294 (22%)
Query: 12 ELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKL 71
E C +CL EPV + C HNFC+ CI W CP C + + L N +L
Sbjct: 26 EASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYR-SLRPNRQL 84
Query: 72 TNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARG 131
++VE L A K +R E+ C
Sbjct: 85 GSMVE--------------------IAKQLQAVKRKIRDESLC----------------- 107
Query: 132 HLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRK 191
PQH+ C +Q AVC C S H+ H+V ++ E ++
Sbjct: 108 --------------PQHHEALSLFCYEDQEAVCLICA-ISHTHRAHTVVPLDDATQEYKE 152
Query: 192 MLMKQQDRLEEREQDI----EDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDL 247
L K + LE++ Q+I + K KRLVE + ++++ ++E+LH+ LDE+
Sbjct: 153 KLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESR----RQQILREFEELHRRLDEEQ 208
Query: 248 RQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGS-----LQLLFDKTEDV 296
+ + L++ + A HLG++ ++ L LQ F+ +DV
Sbjct: 209 QVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDV 262
>gi|30023818 tripartite motif protein 50A [Homo sapiens]
Length = 487
Score = 79.3 bits (194), Expect = 8e-15
Identities = 57/243 (23%), Positives = 101/243 (41%), Gaps = 58/243 (23%)
Query: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNL 69
E+ L CPICL VF EP+ L C H++C+GC+ +RCP C QA + L N+
Sbjct: 11 EDWLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSL-PNV 69
Query: 70 KLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTA 129
L ++E R P P KVC+ H + P +
Sbjct: 70 SLARVIEAL------------------RLPGDPEPKVCV-------------HHRNPLS- 97
Query: 130 RGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEI 189
CE +Q +C C G+HQ H V V + +
Sbjct: 98 ------------------------LFCEKDQELICGLCGLL-GSHQHHPVTPVSTVYSRM 132
Query: 190 RKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQ 249
++ L L++ ++ +++ + KL +++ + + + +R ++++LH L+DE+ +
Sbjct: 133 KEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQELHHLVDEEKAR 192
Query: 250 TVE 252
+E
Sbjct: 193 CLE 195
>gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like
protein 1 [Homo sapiens]
Length = 446
Score = 78.2 bits (191), Expect = 2e-14
Identities = 65/294 (22%), Positives = 118/294 (40%), Gaps = 53/294 (18%)
Query: 1 MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYN 60
M ++ + F++EL C ICL+ V+PV + C H+FCR C+ +W + CP C + +
Sbjct: 1 MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREP-S 59
Query: 61 QKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQ 120
K + N+ L N+V R+ + L E C +H Q
Sbjct: 60 PKMDFKTNILLKNLV-----------------TIARKA----SLWQFLSSEKQICGTHRQ 98
Query: 121 THLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVC 180
T + C+ ++ +C C S H H
Sbjct: 99 T------------------------------KKMFCDMDKSLLC-LLCSNSQEHGAHKHY 127
Query: 181 DVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLH 240
+E E R+ L+KQ L ++ Q+ + LY+ L+ V + +R +Y KLH
Sbjct: 128 PIEEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQMIRNEYRKLH 187
Query: 241 QLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTE 294
+L ++ +Q +E L+K + + + + ++ + K++ L + K E
Sbjct: 188 PVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPE 241
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 76.3 bits (186), Expect = 7e-14
Identities = 76/357 (21%), Positives = 144/357 (40%), Gaps = 72/357 (20%)
Query: 10 EEELICPICLHVFVEPVQ-LPCKHNFCRGCIGEAWAKDS--------------GLVRCPE 54
E++LICPICL +F +PV LPC+HN CR C + + + G RCP
Sbjct: 21 EKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRCPS 80
Query: 55 CNQAY----NQKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRC 110
C + GL++NL + NI++ + ++ P +K
Sbjct: 81 CRHEVVLDRHGVYGLQRNLLVENIIDIY-----------------KQESTRPEKK----S 119
Query: 111 EAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYY 170
+ P C+ H + + N Y L +CE V C C +
Sbjct: 120 DQPMCEEHEEERI-------------------------NIYCL-NCE---VPTCSLCKVF 150
Query: 171 SGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKE 230
GAH+ V + + L L ++ + +LE + +EE + K+
Sbjct: 151 -GAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQ 209
Query: 231 EVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLF 290
E+ +++ L+ +L+E + +V+ + Q + A + ++ KL+ S
Sbjct: 210 ELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFM 269
Query: 291 DKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKM 347
D+ E F++N K+ +L ++ + + + G+ N F + ++EK +R++
Sbjct: 270 DEPEMAVFLQNAKT--LLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREI 324
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 76.3 bits (186), Expect = 7e-14
Identities = 76/357 (21%), Positives = 144/357 (40%), Gaps = 72/357 (20%)
Query: 10 EEELICPICLHVFVEPVQ-LPCKHNFCRGCIGEAWAKDS--------------GLVRCPE 54
E++LICPICL +F +PV LPC+HN CR C + + + G RCP
Sbjct: 21 EKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRCPS 80
Query: 55 CNQAY----NQKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRC 110
C + GL++NL + NI++ + ++ P +K
Sbjct: 81 CRHEVVLDRHGVYGLQRNLLVENIIDIY-----------------KQESTRPEKK----S 119
Query: 111 EAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYY 170
+ P C+ H + + N Y L +CE V C C +
Sbjct: 120 DQPMCEEHEEERI-------------------------NIYCL-NCE---VPTCSLCKVF 150
Query: 171 SGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKE 230
GAH+ V + + L L ++ + +LE + +EE + K+
Sbjct: 151 -GAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQ 209
Query: 231 EVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLF 290
E+ +++ L+ +L+E + +V+ + Q + A + ++ KL+ S
Sbjct: 210 ELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFM 269
Query: 291 DKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKM 347
D+ E F++N K+ +L ++ + + + G+ N F + ++EK +R++
Sbjct: 270 DEPEMAVFLQNAKT--LLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREI 324
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 76.3 bits (186), Expect = 7e-14
Identities = 76/357 (21%), Positives = 144/357 (40%), Gaps = 72/357 (20%)
Query: 10 EEELICPICLHVFVEPVQ-LPCKHNFCRGCIGEAWAKDS--------------GLVRCPE 54
E++LICPICL +F +PV LPC+HN CR C + + + G RCP
Sbjct: 21 EKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRCPS 80
Query: 55 CNQAY----NQKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRC 110
C + GL++NL + NI++ + ++ P +K
Sbjct: 81 CRHEVVLDRHGVYGLQRNLLVENIIDIY-----------------KQESTRPEKK----S 119
Query: 111 EAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYY 170
+ P C+ H + + N Y L +CE V C C +
Sbjct: 120 DQPMCEEHEEERI-------------------------NIYCL-NCE---VPTCSLCKVF 150
Query: 171 SGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKE 230
GAH+ V + + L L ++ + +LE + +EE + K+
Sbjct: 151 -GAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQ 209
Query: 231 EVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLF 290
E+ +++ L+ +L+E + +V+ + Q + A + ++ KL+ S
Sbjct: 210 ELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFM 269
Query: 291 DKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKM 347
D+ E F++N K+ +L ++ + + + G+ N F + ++EK +R++
Sbjct: 270 DEPEMAVFLQNAKT--LLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREI 324
>gi|169202730 PREDICTED: similar to hCG1802386 [Homo sapiens]
Length = 452
Score = 75.1 bits (183), Expect = 2e-13
Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 59/276 (21%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELICPIC++ F++PV + C H+FCR C W + L +C +C + Q +N
Sbjct: 9 FQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWQDMAVLAQCSKCKKTTRQ-----RN 63
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
LK TNI C + A+K LR
Sbjct: 64 LK-TNI--------------------CLKNMASIARKASLR------------------- 83
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
L + + C H + CE ++ +C C S H+ H C E E
Sbjct: 84 ---QFLSSEEQI----CGTHRETKEMFCEVDKSLLC-LLCSNSQEHRNHRHCPTEWAAEE 135
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
R+ L+++ L + + L + R ++ V+ E +R +Y K+ E+ +
Sbjct: 136 RREELLRKMQSLWRKMCENHRNLNMATNRIRCWKDYVSLRIEAIRAEYHKMVAFFHEEEQ 195
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGE-RMQEAKKLL 283
+ +E L K E+ Q L+ + RM+ +++LL
Sbjct: 196 RHLERLQKE-----GEDIFQQLNKSKARMEHSRELL 226
>gi|89034675 PREDICTED: similar to hCG1802386 [Homo sapiens]
Length = 452
Score = 75.1 bits (183), Expect = 2e-13
Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 59/276 (21%)
Query: 9 FEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKN 68
F+ ELICPIC++ F++PV + C H+FCR C W + L +C +C + Q +N
Sbjct: 9 FQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWQDMAVLAQCSKCKKTTRQ-----RN 63
Query: 69 LKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST 128
LK TNI C + A+K LR
Sbjct: 64 LK-TNI--------------------CLKNMASIARKASLR------------------- 83
Query: 129 ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNE 188
L + + C H + CE ++ +C C S H+ H C E E
Sbjct: 84 ---QFLSSEEQI----CGTHRETKEMFCEVDKSLLC-LLCSNSQEHRNHRHCPTEWAAEE 135
Query: 189 IRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLR 248
R+ L+++ L + + L + R ++ V+ E +R +Y K+ E+ +
Sbjct: 136 RREELLRKMQSLWRKMCENHRNLNMATNRIRCWKDYVSLRIEAIRAEYHKMVAFFHEEEQ 195
Query: 249 QTVEVLDKAQAKFCSENAAQALHLGE-RMQEAKKLL 283
+ +E L K E+ Q L+ + RM+ +++LL
Sbjct: 196 RHLERLQKE-----GEDIFQQLNKSKARMEHSRELL 226
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,312,195
Number of Sequences: 37866
Number of extensions: 1407293
Number of successful extensions: 11271
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 344
Number of HSP's successfully gapped in prelim test: 644
Number of HSP's that attempted gapping in prelim test: 8528
Number of HSP's gapped (non-prelim): 2788
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.