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Search of human proteins with 14577917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14577917 Epstein-Barr virus induced 3 precursor [Homo
sapiens]
(229 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens] 480 e-136
gi|22212918 ciliary neurotrophic factor receptor preproprotein [... 102 3e-22
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H... 102 3e-22
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 96 2e-20
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 96 2e-20
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 96 2e-20
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 58 6e-09
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 58 6e-09
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 58 6e-09
gi|4758822 nephrin precursor [Homo sapiens] 55 7e-08
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 52 3e-07
gi|24497438 interleukin 12B precursor [Homo sapiens] 51 7e-07
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi... 50 1e-06
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap... 50 1e-06
gi|4506107 prolactin receptor [Homo sapiens] 50 2e-06
gi|119220552 sidekick 1 [Homo sapiens] 46 2e-05
gi|155969693 myomesin family, member 3 [Homo sapiens] 45 5e-05
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 45 7e-05
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 45 7e-05
gi|222352127 sidekick 2 [Homo sapiens] 44 2e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 42 4e-04
gi|110349717 titin isoform novex-2 [Homo sapiens] 42 4e-04
gi|110349713 titin isoform novex-1 [Homo sapiens] 42 4e-04
gi|110349715 titin isoform N2-B [Homo sapiens] 42 4e-04
gi|4503993 growth hormone receptor precursor [Homo sapiens] 42 6e-04
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 41 0.001
gi|157384973 tenascin R [Homo sapiens] 40 0.001
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 40 0.002
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 37 0.011
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 37 0.014
>gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens]
Length = 229
Score = 480 bits (1236), Expect = e-136
Identities = 229/229 (100%), Positives = 229/229 (100%)
Query: 1 MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV 60
MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV
Sbjct: 1 MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV 60
Query: 61 SFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVP 120
SFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVP
Sbjct: 61 SFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVP 120
Query: 121 FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV 180
FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV
Sbjct: 121 FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV 180
Query: 181 GPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK 229
GPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK
Sbjct: 181 GPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK 229
>gi|22212918 ciliary neurotrophic factor receptor preproprotein
[Homo sapiens]
Length = 372
Score = 102 bits (254), Expect = 3e-22
Identities = 60/196 (30%), Positives = 97/196 (49%), Gaps = 9/196 (4%)
Query: 31 PRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCT 90
P + CR++ YP CSW LP +P T+ + + C + C
Sbjct: 112 PVLSCRSNTYPKGFYCSWHLP------TPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCH 165
Query: 91 ITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAE--RQLQVQ 148
I + LFS Y ++++ + G +++ + F I+KPDPPE V P+ R+L+V
Sbjct: 166 IRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVT 225
Query: 149 WEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDL 208
W+ P +WP PE F LK+++RY+ ++ V + T+ + Y +QVAA+D
Sbjct: 226 WQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD- 284
Query: 209 TDYGELSDWSLPATAT 224
+ G SDWS+ A AT
Sbjct: 285 NEIGTWSDWSVAAHAT 300
>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
sapiens]
Length = 372
Score = 102 bits (254), Expect = 3e-22
Identities = 60/196 (30%), Positives = 97/196 (49%), Gaps = 9/196 (4%)
Query: 31 PRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCT 90
P + CR++ YP CSW LP +P T+ + + C + C
Sbjct: 112 PVLSCRSNTYPKGFYCSWHLP------TPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCH 165
Query: 91 ITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAE--RQLQVQ 148
I + LFS Y ++++ + G +++ + F I+KPDPPE V P+ R+L+V
Sbjct: 166 IRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVT 225
Query: 149 WEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDL 208
W+ P +WP PE F LK+++RY+ ++ V + T+ + Y +QVAA+D
Sbjct: 226 WQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD- 284
Query: 209 TDYGELSDWSLPATAT 224
+ G SDWS+ A AT
Sbjct: 285 NEIGTWSDWSVAAHAT 300
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 96.3 bits (238), Expect = 2e-20
Identities = 71/218 (32%), Positives = 106/218 (48%), Gaps = 24/218 (11%)
Query: 24 PPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYR----LGMAARGHS--- 76
PPA P V C+A+ Y C+W+ P+ S P ++ +YR LG ++ S
Sbjct: 112 PPAR---PVVSCQAADYE-NFSCTWS--PSQISGLPTRYLTSYRKKTVLGADSQRRSPST 165
Query: 77 --WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEG 134
WPC Q + C + + +S Y +NVT V+P G+S+ + + I++PDPP+G
Sbjct: 166 GPWPCPQDPLGAARCVVHGAEFWSQ--YRINVTEVNPLGASTRLLDVSLQSILRPDPPQG 223
Query: 135 VRLS--PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRA 192
+R+ P R+L+ W P SWP F LK+ ++Y+ + V P I A
Sbjct: 224 LRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDA 283
Query: 193 VR--PRARYYVQVAAQDLTDYGELSDWSLPATATMSLG 228
V P A V+V+A+D D G S WS A T S G
Sbjct: 284 VAGLPHA---VRVSARDFLDAGTWSTWSPEAWGTPSTG 318
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 96.3 bits (238), Expect = 2e-20
Identities = 71/218 (32%), Positives = 106/218 (48%), Gaps = 24/218 (11%)
Query: 24 PPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYR----LGMAARGHS--- 76
PPA P V C+A+ Y C+W+ P+ S P ++ +YR LG ++ S
Sbjct: 112 PPAR---PVVSCQAADYE-NFSCTWS--PSQISGLPTRYLTSYRKKTVLGADSQRRSPST 165
Query: 77 --WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEG 134
WPC Q + C + + +S Y +NVT V+P G+S+ + + I++PDPP+G
Sbjct: 166 GPWPCPQDPLGAARCVVHGAEFWSQ--YRINVTEVNPLGASTRLLDVSLQSILRPDPPQG 223
Query: 135 VRLS--PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRA 192
+R+ P R+L+ W P SWP F LK+ ++Y+ + V P I A
Sbjct: 224 LRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDA 283
Query: 193 VR--PRARYYVQVAAQDLTDYGELSDWSLPATATMSLG 228
V P A V+V+A+D D G S WS A T S G
Sbjct: 284 VAGLPHA---VRVSARDFLDAGTWSTWSPEAWGTPSTG 318
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 96.3 bits (238), Expect = 2e-20
Identities = 71/218 (32%), Positives = 106/218 (48%), Gaps = 24/218 (11%)
Query: 24 PPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYR----LGMAARGHS--- 76
PPA P V C+A+ Y C+W+ P+ S P ++ +YR LG ++ S
Sbjct: 112 PPAR---PVVSCQAADYE-NFSCTWS--PSQISGLPTRYLTSYRKKTVLGADSQRRSPST 165
Query: 77 --WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEG 134
WPC Q + C + + +S Y +NVT V+P G+S+ + + I++PDPP+G
Sbjct: 166 GPWPCPQDPLGAARCVVHGAEFWSQ--YRINVTEVNPLGASTRLLDVSLQSILRPDPPQG 223
Query: 135 VRLS--PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRA 192
+R+ P R+L+ W P SWP F LK+ ++Y+ + V P I A
Sbjct: 224 LRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDA 283
Query: 193 VR--PRARYYVQVAAQDLTDYGELSDWSLPATATMSLG 228
V P A V+V+A+D D G S WS A T S G
Sbjct: 284 VAGLPHA---VRVSARDFLDAGTWSTWSPEAWGTPSTG 318
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 58.2 bits (139), Expect = 6e-09
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 125 HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPI- 183
+++KPDPP G+ + + L++ W P PFP L+Y ++Y I
Sbjct: 233 NMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFP----LQYQVKYSENSTTVIREADKIV 288
Query: 184 EATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATAT 224
ATS ++ ++ P + Y VQV + L G SDWS P T
Sbjct: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFT 329
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 96 LFSMAPYVLNVTAVHPWGS-SSSFVPFITEHIIKPDPPEGVRLS-PLAERQLQVQWEPPG 153
+F ++ Y + + H GS S + + ++KP PP V+ + L++ WE P
Sbjct: 503 IFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKP- 561
Query: 154 SWPFPEIFSLKYWIRYKRQGAA---RFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
FPE +L++ IRY G + + V ++ S L A Y VQV + L
Sbjct: 562 --VFPEN-NLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDG 618
Query: 211 YGELSDWSLPA 221
G S+WS PA
Sbjct: 619 LGYWSNWSNPA 629
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 58.2 bits (139), Expect = 6e-09
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 125 HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPI- 183
+++KPDPP G+ + + L++ W P PFP L+Y ++Y I
Sbjct: 233 NMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFP----LQYQVKYSENSTTVIREADKIV 288
Query: 184 EATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATAT 224
ATS ++ ++ P + Y VQV + L G SDWS P T
Sbjct: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFT 329
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 96 LFSMAPYVLNVTAVHPWGS-SSSFVPFITEHIIKPDPPEGVRLS-PLAERQLQVQWEPPG 153
+F ++ Y + + H GS S + + ++KP PP V+ + L++ WE P
Sbjct: 503 IFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKP- 561
Query: 154 SWPFPEIFSLKYWIRYKRQGAA---RFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
FPE +L++ IRY G + + V ++ S L A Y VQV + L
Sbjct: 562 --VFPEN-NLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDG 618
Query: 211 YGELSDWSLPA 221
G S+WS PA
Sbjct: 619 LGYWSNWSNPA 629
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 58.2 bits (139), Expect = 6e-09
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Query: 125 HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPI- 183
+++KPDPP G+ + + L++ W P PFP L+Y ++Y I
Sbjct: 233 NMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFP----LQYQVKYSENSTTVIREADKIV 288
Query: 184 EATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATAT 224
ATS ++ ++ P + Y VQV + L G SDWS P T
Sbjct: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFT 329
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 96 LFSMAPYVLNVTAVHPWGS-SSSFVPFITEHIIKPDPPEGVRLS-PLAERQLQVQWEPPG 153
+F ++ Y + + H GS S + + ++KP PP V+ + L++ WE P
Sbjct: 503 IFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKP- 561
Query: 154 SWPFPEIFSLKYWIRYKRQGAA---RFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
FPE +L++ IRY G + + V ++ S L A Y VQV + L
Sbjct: 562 --VFPEN-NLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDG 618
Query: 211 YGELSDWSLPA 221
G S+WS PA
Sbjct: 619 LGYWSNWSNPA 629
>gi|4758822 nephrin precursor [Homo sapiens]
Length = 1241
Score = 54.7 bits (130), Expect = 7e-08
Identities = 37/132 (28%), Positives = 64/132 (48%), Gaps = 9/132 (6%)
Query: 88 SCTITDVQLFSMAPYVL-NVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQ 146
S +T + + Y L TA + GS + + ++ I +PDPP G+++ L +
Sbjct: 901 SSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVS--ISRPDPPSGLKVVSLTPHSVG 958
Query: 147 VQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATSFILRAVRPRARYYVQVA 204
++W+P P+ ++ IRY+ G FH V P +AT+F L ++P RY V +
Sbjct: 959 LEWKPGFDGGLPQ----RFCIRYEALGTPGFHYVDVVPPQATTFTLTGLQPSTRYRVWLL 1014
Query: 205 AQDLTDYGELSD 216
A + L+D
Sbjct: 1015 ASNALGDSGLAD 1026
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 52.4 bits (124), Expect = 3e-07
Identities = 59/193 (30%), Positives = 83/193 (43%), Gaps = 22/193 (11%)
Query: 46 CSWTLPPAPNSTSPVSFIATYRLGMAAR--GHSWPCLQ-QTPTSTSCTIT-DVQLFSMAP 101
C WT P + Y L R G C + T SC I D+ LF+ P
Sbjct: 153 CRWT----PGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFT--P 206
Query: 102 YVLNVTAVHPWGSSSSFVPFITE-HIIKPDPPEGVRLSPLA--ERQLQVQW-EPPGSWPF 157
Y + V A + GS+ S V + ++ DPP V +S + E QL V+W PP F
Sbjct: 207 YEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDF 266
Query: 158 PEIFSLKYWIRYKRQGAARFHRVGPIE-ATSFILRAVRPRARYYVQVAAQDLTDYGE--- 213
+F KY IRY+ + + + V + TS L ++P Y+VQV YG
Sbjct: 267 --LFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKA 324
Query: 214 --LSDWSLPATAT 224
S+WS P A+
Sbjct: 325 GIWSEWSHPTAAS 337
>gi|24497438 interleukin 12B precursor [Homo sapiens]
Length = 328
Score = 51.2 bits (121), Expect = 7e-07
Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 101 PYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLA-ERQLQVQWEPPGSWPFP- 158
P + V AVH + F IIKPDPP+ ++L PL RQ++V WE P +W P
Sbjct: 207 PIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPH 266
Query: 159 EIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWS 218
FSL + ++ QG ++ + + T V R + V AQD S+W+
Sbjct: 267 SYFSLTFCVQV--QGKSKREKKDRV-FTDKTSATVICRKNASISVRAQDRYYSSSWSEWA 323
>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
sapiens]
Length = 468
Score = 50.4 bits (119), Expect = 1e-06
Identities = 49/207 (23%), Positives = 85/207 (41%), Gaps = 23/207 (11%)
Query: 31 PRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC-LQQTPTSTSC 89
P++ C V C W P+ T+ + A PC Q SC
Sbjct: 117 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 176
Query: 90 TITDVQLFSMAPYVLNVTAVHPWGSS-SSFVPFITEHIIKPDPPEGVRLSPLAE--RQLQ 146
+ V + Y++++ GS S F I++PDPP + ++ +A R L
Sbjct: 177 QLA-VPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLS 235
Query: 147 VQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRA--------- 197
V W+ P SW + L++ +RY+ + + F T+++++ ++
Sbjct: 236 VTWQDPHSWN-SSFYRLRFELRYRAERSKTF--------TTWMVKDLQHHCVIHDAWSGL 286
Query: 198 RYYVQVAAQDLTDYGELSDWSLPATAT 224
R+ VQ+ AQ+ GE S+WS A T
Sbjct: 287 RHVVQLRAQEEFGQGEWSEWSPEAMGT 313
>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
sapiens]
Length = 365
Score = 50.4 bits (119), Expect = 1e-06
Identities = 49/207 (23%), Positives = 85/207 (41%), Gaps = 23/207 (11%)
Query: 31 PRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC-LQQTPTSTSC 89
P++ C V C W P+ T+ + A PC Q SC
Sbjct: 117 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 176
Query: 90 TITDVQLFSMAPYVLNVTAVHPWGSS-SSFVPFITEHIIKPDPPEGVRLSPLAE--RQLQ 146
+ V + Y++++ GS S F I++PDPP + ++ +A R L
Sbjct: 177 QLA-VPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLS 235
Query: 147 VQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRA--------- 197
V W+ P SW + L++ +RY+ + + F T+++++ ++
Sbjct: 236 VTWQDPHSWN-SSFYRLRFELRYRAERSKTF--------TTWMVKDLQHHCVIHDAWSGL 286
Query: 198 RYYVQVAAQDLTDYGELSDWSLPATAT 224
R+ VQ+ AQ+ GE S+WS A T
Sbjct: 287 RHVVQLRAQEEFGQGEWSEWSPEAMGT 313
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 50.1 bits (118), Expect = 2e-06
Identities = 53/188 (28%), Positives = 79/188 (42%), Gaps = 22/188 (11%)
Query: 46 CSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLN 105
C W P + P ++ TY H P T SC Y++
Sbjct: 46 CWWR--PGTDGGLPTNYSLTYHREGETLMHECPDYI-TGGPNSCHFGKQYTSMWRTYIMM 102
Query: 106 VTAVHPWGSSSSFVPFI-TEHIIKPDPPE--GVRLSPLAERQ--LQVQWEPPG------S 154
V A + GSS S ++ +I++PDPP V + +R+ L ++W PP
Sbjct: 103 VNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTG 162
Query: 155 WPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGEL 214
W F+L Y IR K + AA + + T F + ++ P +Y VQV + D+G
Sbjct: 163 W-----FTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCK--PDHGYW 215
Query: 215 SDWSLPAT 222
S WS PAT
Sbjct: 216 SAWS-PAT 222
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 46.2 bits (108), Expect = 2e-05
Identities = 53/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP L P V+ + R W P PN + + YRL ++ H++ ++
Sbjct: 1379 GPPVRLVFPEVRLTSVRIV------WQPPEEPNGII-LGYQIAYRLASSSP-HTFTTVEV 1430
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAE 142
T T TD+ S + L+ WG TE +P PP + L P AE
Sbjct: 1431 GATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPREL-LVPQAE 1489
Query: 143 ---RQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARY 199
R L++QW P P + R + EAT+ ++ +RP Y
Sbjct: 1490 VTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSY 1549
Query: 200 YVQVAAQDLTDYGELSDWSLPATATMSL 227
+++ A + D G+ SD+S A +L
Sbjct: 1550 KLRLKATN--DIGD-SDFSSETEAVTTL 1574
Score = 37.4 bits (85), Expect = 0.011
Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVP---FITEHIIKPDPP 132
S+ + + TST C +T ++ + Y + +TA + G S + P F+ E P
Sbjct: 1649 SFKTVNSSSTSTMCELTHLKKYRR--YEVIMTAYNIIGESPASAPVEVFVGE-AAPAMAP 1705
Query: 133 EGVRLSPLAERQLQVQWEPP 152
+ V+++PL QL+V W+PP
Sbjct: 1706 QNVQVTPLTASQLEVTWDPP 1725
Score = 35.4 bits (80), Expect = 0.041
Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 15/137 (10%)
Query: 21 RKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCL 80
R PP L +P+ + A ++ W P + SP+ + T ++ RG W
Sbjct: 1476 RPAPPRELLVPQAEVTAR----SLRLQWV--PGSDGASPIRYF-TMQVRELPRGE-WQTY 1527
Query: 81 QQTPT--STSCTITDVQLFSMAPYVLNVTAVHPWGSS---SSFVPFITEHIIKPDPPEGV 135
+ + +T+C + ++ F+ Y L + A + G S S T + +PP V
Sbjct: 1528 SSSISHEATACVVDRLRPFTS--YKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSV 1585
Query: 136 RLSPLAERQLQVQWEPP 152
+P + +QW+PP
Sbjct: 1586 SATPHTTSSVLIQWQPP 1602
Score = 29.3 bits (64), Expect = 2.9
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 10/133 (7%)
Query: 24 PPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV-SFIATYRLGMAARGHSWPCLQQ 82
PP+A P+ + R ++ W PP + +I YRL G
Sbjct: 767 PPSAP--PKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLA-GLPGEYQQRNIT 823
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK---PDPPEGVRLSP 139
+P C +TD+ +++ Y + V A + G F +TE+ ++ PP+ V+
Sbjct: 824 SPEVNYCLVTDLIIWTQ--YEIQVAAYNGAGLGV-FSRAVTEYTLQGVPTAPPQNVQTEA 880
Query: 140 LAERQLQVQWEPP 152
+ +Q W PP
Sbjct: 881 VNSTTIQFLWNPP 893
Score = 28.1 bits (61), Expect = 6.5
Identities = 41/186 (22%), Positives = 66/186 (35%), Gaps = 16/186 (8%)
Query: 38 SRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLF 97
S + AV SW P NS I Y + ++ W +T L
Sbjct: 680 SSHSHAVVLSWVRPFDGNSP-----ILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLT 734
Query: 98 SMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPD-----PPEGVRLSPLAERQLQVQWEPP 152
Y V AV+ G T ++ P+ PP+ + S + + VQW+PP
Sbjct: 735 PARTYQFRVCAVNEVGRGQYSAE--TSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPP 792
Query: 153 GSWPFPEIFSLKYWIRYKRQGAARFHRVGPI---EATSFILRAVRPRARYYVQVAAQDLT 209
+ Y +RY+ G ++ I E ++ + +Y +QVAA +
Sbjct: 793 PETEHNGVLR-GYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGA 851
Query: 210 DYGELS 215
G S
Sbjct: 852 GLGVFS 857
>gi|155969693 myomesin family, member 3 [Homo sapiens]
Length = 1437
Score = 45.1 bits (105), Expect = 5e-05
Identities = 38/148 (25%), Positives = 61/148 (41%), Gaps = 14/148 (9%)
Query: 77 WPCLQQTPTSTS-CTITDVQ---LFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPP 132
W + Q P T C ++D+ + N V + SS + +P PP
Sbjct: 746 WHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPP 805
Query: 133 EGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATS 187
VR S + L +QWEPP G+ P Y + ++ +G+ ++ V GPI T
Sbjct: 806 YDVRASEVRATSLVLQWEPPLYMGAGPV-----TGYHVSFQEEGSEQWKPVTPGPISGTH 860
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELS 215
+ ++P Y QV A + G+ S
Sbjct: 861 LRVSDLQPGKSYVFQVQAMNSAGLGQPS 888
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 44.7 bits (104), Expect = 7e-05
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 11/151 (7%)
Query: 79 CLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGS-SSSFVPFITEHIIKPDPPEGVRL 137
C + T TSCT+ D + V A + G +S + F + +KP+PP + +
Sbjct: 172 CKAKRDTPTSCTV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
Query: 138 SPLAERQ--LQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA----TSFILR 191
E L++ W P + LKY I+Y+ + A+ + ++ P + +SF ++
Sbjct: 231 INSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
Query: 192 AVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
++P Y ++ G SDWS A+
Sbjct: 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 44.7 bits (104), Expect = 7e-05
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 11/151 (7%)
Query: 79 CLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGS-SSSFVPFITEHIIKPDPPEGVRL 137
C + T TSCT+ D + V A + G +S + F + +KP+PP + +
Sbjct: 172 CKAKRDTPTSCTV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
Query: 138 SPLAERQ--LQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA----TSFILR 191
E L++ W P + LKY I+Y+ + A+ + ++ P + +SF ++
Sbjct: 231 INSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
Query: 192 AVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
++P Y ++ G SDWS A+
Sbjct: 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 43.5 bits (101), Expect = 2e-04
Identities = 45/198 (22%), Positives = 78/198 (39%), Gaps = 20/198 (10%)
Query: 43 AVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPY 102
A++ +WT P NS + Y L M+ W L + + ++T L Y
Sbjct: 607 AINLTWTKPFDGNSP-----LIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSY 661
Query: 103 VLNVTAVHPWGSSSSFVPFITEHIIKPD-----PPEGVRLSPLAERQLQVQWEPPGSWPF 157
+ AV+ G TE + P+ PP+ V S + + +QW+PP
Sbjct: 662 QFRLCAVNDVGKGQFSKD--TERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
Query: 158 PEIFSLKYWIRYKRQG---AARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYG-- 212
I Y IRY G +F + + + +L + Y ++VAA + G
Sbjct: 720 NGILK-GYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVY 778
Query: 213 --ELSDWSLPATATMSLG 228
++++W+L T+ G
Sbjct: 779 SSKVTEWTLQGVPTVPPG 796
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/202 (22%), Positives = 81/202 (40%), Gaps = 18/202 (8%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP + P V+ + R W P APN +++ T+RL ++
Sbjct: 1302 GPPMGILFPEVRTTSVRL------IWQPPAAPNGII-LAYQITHRLNTTT-ANTATVEVL 1353
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEG--VRLSPL 140
P++ T T ++ S+ + + WG ++ + TE +P PP V+ +
Sbjct: 1354 APSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDV 1413
Query: 141 AERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQ---GAARFHRVG-PIEATSFILRAVRPR 196
R + + WEP P ++Y+ R+ G H A+SFI+ ++P
Sbjct: 1414 RARSVLLSWEPGSDGLSP----VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPF 1469
Query: 197 ARYYVQVAAQDLTDYGELSDWS 218
Y +V A + E S+ S
Sbjct: 1470 TSYKFRVKATNDIGDSEFSEES 1491
Score = 34.7 bits (78), Expect = 0.070
Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 13/131 (9%)
Query: 95 QLFSMAPYVL---NVTAVHPWGSSSSFVPFITEHIIK--PDPPEGVRLSPLAERQLQVQW 149
QL + YVL V A G S P I E + P PP G+ + +++ W
Sbjct: 1262 QLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIW 1321
Query: 150 EPPGSWPFPEIFSLKYWIRYK----RQGAARFHRVGPIEATSFILRAVRPRARYYVQVAA 205
+PP + P L Y I ++ A + P A + ++P + Y ++ A
Sbjct: 1322 QPPAA---PNGIILAYQITHRLNTTTANTATVEVLAP-SARQYTATGLKPESVYLFRITA 1377
Query: 206 QDLTDYGELSD 216
Q +GE ++
Sbjct: 1378 QTRKGWGEAAE 1388
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 42.0 bits (97), Expect = 4e-04
Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 9/112 (8%)
Query: 45 DCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
D WT+P + ++I R R W + T T CT+T + S+ YV
Sbjct: 14101 DLKWTVPEKDGGSPITNYIVEKR---DVRRKGWQTVDTTVKDTKCTVTPLTEGSL--YVF 14155
Query: 105 NVTAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
V A + G S + P PP + + + +R + ++WEPP
Sbjct: 14156 RVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP 14207
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/180 (25%), Positives = 71/180 (39%), Gaps = 8/180 (4%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW PPA + S ++ + A G W + + T+C I V L A Y V
Sbjct: 30743 SWK-PPADDGGSWITNYVVEKCE-AKEGAEWQLVSSAISVTTCRI--VNLTENAGYYFRV 30798
Query: 107 TAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
+A + +G S S V I KP P ++ + + V W+PP S +I +
Sbjct: 30799 SAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRN 30858
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
R K+Q I T F ++ + Y +V ++L E S+ S P T
Sbjct: 30859 YYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT 30918
Score = 37.7 bits (86), Expect = 0.008
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 9/165 (5%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW P + +I R A +W + TS +T+ L Y V
Sbjct: 18718 SWAPPENDGGSQVTHYIVEKR---EADRKTWSTVTPEVKKTSFHVTN--LVPGNEYYFRV 18772
Query: 107 TAVHPWGSS-SSFVP---FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
TAV+ +G + VP ++ + +PDPP + ++ + + + W PP +I
Sbjct: 18773 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 18832
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQD 207
R + Q A R+ ++ S ++ ++ +Y +VAA++
Sbjct: 18833 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARN 18877
Score = 37.4 bits (85), Expect = 0.011
Identities = 33/163 (20%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Query: 52 PAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHP 111
PA + P I + M + ++ P ++ TI D + Y++ AV+
Sbjct: 13711 PATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE--AVNV 13768
Query: 112 WGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKR 171
G +++ V + KP PP ++ + + W PP +I Y + +
Sbjct: 13769 CGRATAVVE--VNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI--TNYVVERRA 13824
Query: 172 QGAARFHRV-GPIEATSFILRAVRPRARYYVQVAAQDLTDYGE 213
+ +H++ ++ T+F + P Y +VAA+++ GE
Sbjct: 13825 TDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 13867
Score = 37.0 bits (84), Expect = 0.014
Identities = 47/211 (22%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V V +W P +++ R + R + +
Sbjct: 13192 GPPLNVTITDVN------RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT--AMTV 13243
Query: 83 TPTSTSCTITDV---QLFSMAPYVLNVTAVHPWGSSSSFVPFI--TEHIIKPDPPEGVRL 137
S T+TDV Q +S N V G S+ PF+ + I +P PP +
Sbjct: 13244 RAEDLSATVTDVVEGQEYSFRVRAQNRIGV---GKPSAATPFVKVADPIERPSPPVNLTS 13300
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRA 192
S + +Q++WEPP G P L Y I +G + R + ++ +
Sbjct: 13301 SDQTQSSVQLKWEPPLKDGGSPI-----LGYIIERCEEGKDNWIRCNMKLVPELTYKVTG 13355
Query: 193 VRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ +Y +V+A++ + S+ P TA
Sbjct: 13356 LEKGNKYLYRVSAENKAGVSDPSEILGPLTA 13386
Score = 35.8 bits (81), Expect = 0.031
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLSPLA 141
T + TS + +V + Y L + SS + F+T ++ P PP ++++ +
Sbjct: 22992 TSSFTSLVLDNVNRYDSGKYTLTLE-----NSSGTKSAFVTVRVLDTPSPPVNLKVTEIT 23046
Query: 142 ERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHR--VGPIEATSFILRAVRP 195
+ + + WEPP GS +K +I KR+ + + V S+ + ++
Sbjct: 23047 KDSVSITWEPPLLDGGS-------KIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQE 23099
Query: 196 RARYYVQVAAQDLTDYG 212
YY +V A++ +YG
Sbjct: 23100 GCSYYFRVTAEN--EYG 23114
Score = 35.4 bits (80), Expect = 0.041
Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 27/216 (12%)
Query: 20 GRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC 79
GR GPP + A + + SW P + +++ R A +W
Sbjct: 16215 GRPGPPVG-PIKFESVSADQMTL----SWFPPKDDGGSKITNYVIEKR---EANRKTWVH 16266
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSF--VPFITEHIIK-PDPPEGVR 136
+ P CT T +L YV + A + +G P ++ P P+
Sbjct: 16267 VSSEPKE--CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 16324
Query: 137 LSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEA----TS 187
+S + + V WE P G P YW+ K + R+ RV PI+A S
Sbjct: 16325 VSSVTRNSMTVNWEEPEYDGGSPV-----TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVS 16379
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ + + + Y +V A + G S S PATA
Sbjct: 16380 YKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 16415
Score = 35.4 bits (80), Expect = 0.041
Identities = 31/140 (22%), Positives = 62/140 (44%), Gaps = 21/140 (15%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLS 138
++ T + T + +V F Y+L V SS S F+ ++ P PP+ +++
Sbjct: 21907 IESTSSYTLLIVGNVNRFDSGKYILTVE-----NSSGSKSAFVNVRVLDTPGPPQDLKVK 21961
Query: 139 PLAERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA--TSFILRA 192
+ + + + W+PP GS +K +I KR+ + + TS+ +
Sbjct: 21962 EVTKTSVTLTWDPPLLDGGS-------KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQ 22014
Query: 193 VRPRARYYVQVAAQDLTDYG 212
++ YY +V A++ +YG
Sbjct: 22015 LQEGCSYYFRVLAEN--EYG 22032
Score = 34.7 bits (78), Expect = 0.070
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSF 188
PDPP GV++S ++ + + W P S +I Y + A R+ RVG T +
Sbjct: 31122 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKI--TNYIVEKCATTAERWLRVGQARETRY 31179
Query: 189 ILRAVRPRARYYVQVAAQDLTDYGELSDWSLP 220
+ + + Y +V A++ + S+ S P
Sbjct: 31180 TVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 31211
Score = 34.3 bits (77), Expect = 0.091
Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 10/153 (6%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSS----SSFVPFITEHIIKPDP 131
+W + T T + T+ L Y + A + G +S I E I P+
Sbjct: 16662 AWTPVTYTVTRQNATVQG--LIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 16719
Query: 132 PEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFI 189
PE + + + + + + W PP EI + Y + + G +FH+V + + +
Sbjct: 16720 PEDLEVKEVTKNTVTLTWNPPKYDGGSEI--INYVLESRLIGTEKFHKVTNDNLLSRKYT 16777
Query: 190 LRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
++ ++ Y +V+A ++ G+ S + P T
Sbjct: 16778 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPIT 16810
Score = 33.1 bits (74), Expect = 0.20
Identities = 41/183 (22%), Positives = 75/183 (40%), Gaps = 16/183 (8%)
Query: 46 CSWTL-PPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
CS T PP + S +S + + +W + + S +T +L YV
Sbjct: 23736 CSLTWSPPLQDGGSDISHYVVEKRETSRL--AWTVVASEVVTNSLKVT--KLLEGNEYVF 23791
Query: 105 NVTAVHPWGSSSSF--VPFITEH-IIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIF 161
+ AV+ +G P + ++ + P PP+ + ++ +A+ + V W P S EI
Sbjct: 23792 RIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI- 23850
Query: 162 SLKYWIRYKRQGAARFHRVGPIEATSFILR--AVRPRARYYVQVAAQDLTDYGELSDWSL 219
+ Y + + + R+ + T LR + Y +V+A++ GE S
Sbjct: 23851 -IGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS---- 23905
Query: 220 PAT 222
PAT
Sbjct: 23906 PAT 23908
Score = 33.1 bits (74), Expect = 0.20
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEG-VRLSPLAERQLQVQWEPP 152
+TA + G++ +F+ + + +P PP G V +S + E + ++WEPP
Sbjct: 26549 ITAANSSGTTKAFINIVV--LDRPGPPTGPVVISDITEESVTLKWEPP 26594
Score = 32.3 bits (72), Expect = 0.35
Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 5/126 (3%)
Query: 105 NVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLK 164
++T V+P G + FV + P P +++S + + V W PP + ++
Sbjct: 18677 SLTLVNPAGEKAVFVN--VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQV--TH 18732
Query: 165 YWIRYKRQGAARFHRVGP-IEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
Y + + + V P ++ TSF + + P YY +V A + G +D P A
Sbjct: 18733 YIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA 18792
Query: 224 TMSLGK 229
+ L +
Sbjct: 18793 SDPLSE 18798
Score = 32.3 bits (72), Expect = 0.35
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ TPTS+ TI Y +TA +P+G+ V + P PP V +S
Sbjct: 20428 ITSTPTSSMLTIKYATRKDAGEYT--ITATNPFGTKVEHVKVTVLDV--PGPPGPVEISN 20483
Query: 140 LAERQLQVQWEPP 152
++ + + W PP
Sbjct: 20484 VSAEKATLTWTPP 20496
Score = 32.0 bits (71), Expect = 0.45
Identities = 32/148 (21%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII------KP 129
+W + T T+ IT +L + Y + A + +G S+ P ++ +I +P
Sbjct: 24451 TWHMVSATVARTTIKIT--KLKTGTEYQFRIFAENRYGKSA---PLDSKAVIVQYPFKEP 24505
Query: 130 DPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATS 187
PP ++ +++ Q+ VQW P + +I + Y + K + + + ++ PI+ T
Sbjct: 24506 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKI--IGYHLEQKEKNSILWVKLNKTPIQDTK 24563
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELS 215
F + Y +V+A+++ G+ S
Sbjct: 24564 FKTTGLDEGLEYEFKVSAENIVGIGKPS 24591
Score = 32.0 bits (71), Expect = 0.45
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 85 TSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRLSPL 140
T+T T+T L A Y + A + G S +S + KP P + + +
Sbjct: 30385 TTTMYTVTG--LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSI 30442
Query: 141 AERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRAVRPRAR 198
++ + +QWE P EI L YW+ Y++ G + + + I+ F + +
Sbjct: 30443 SKDSVTLQWEKPECDGGKEI--LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATE 30500
Query: 199 YYVQVAAQDLT 209
Y +V A++ T
Sbjct: 30501 YEFRVFAENET 30511
Score = 31.2 bits (69), Expect = 0.77
Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 14/187 (7%)
Query: 43 AVDCSWTLPPAPNSTSPVS-FIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAP 101
++ SW PP + +P+S ++ R A W + ++ T ++ T +L
Sbjct: 29848 SITISWE-PPELDGGAPLSGYVVEQR---DAHRPGWLPVSESVTRSTFKFT--RLTEGNE 29901
Query: 102 YVLNVTAVHPWGSSSSFVPFITE---HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFP 158
YV V A + +G S + E I P PPE +++ ++ + + W PP
Sbjct: 29902 YVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGS 29961
Query: 159 EIFSLKYWIRYKRQGAARFHRVG--PIEATSFILRAVRPRARYYVQVAAQDLTDYGELSD 216
++ Y + K A R+ RV P+ T + + Y +V A + G+ S
Sbjct: 29962 QVTG--YIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 30019
Query: 217 WSLPATA 223
S P A
Sbjct: 30020 PSKPIVA 30026
Score = 30.8 bits (68), Expect = 1.0
Identities = 43/202 (21%), Positives = 78/202 (38%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV-SFIATYRLGMAARGHSWPCLQ 81
GPP + + V + +WT PP + SP+ S+I R W +
Sbjct: 20474 GPPGPVEISNVSAEKATL------TWT-PPLEDGGSPIKSYILEKR---ETSRLLWTVVS 20523
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSS---SFVPFITEHIIKPDPPEGVRLS 138
+ SC +L Y+ V+AV+ +G S + + P PPE +S
Sbjct: 20524 ED--IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVS 20581
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFILRAVRPR 196
+ + V W+ P EI Y + + + + R+ R P+ + ++
Sbjct: 20582 NVTKNTATVSWKRPVDDGGSEITG--YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEG 20639
Query: 197 ARYYVQVAAQDLTDYGELSDWS 218
+ Y +V+A++ G S+ S
Sbjct: 20640 STYEFRVSAENRAGIGPPSEAS 20661
Score = 30.8 bits (68), Expect = 1.0
Identities = 37/202 (18%), Positives = 80/202 (39%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V ++ SW +P ++ R A +W +
Sbjct: 26279 GPPTNITVQDVTKESAVL------SWDVPENDGGAPVKNYHIEKR---EASKKAWVSVTN 26329
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLS 138
S +T++Q A Y V+ + +G +P T+ +K P PPE + ++
Sbjct: 26330 NCNRLSYKVTNLQ--EGAIYYFRVSGENEFGVG---IPAETKEGVKITEKPSPPEKLGVT 26384
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRAR 198
+++ + + W P I + Y + +G + + ++T ++ +R +
Sbjct: 26385 SISKDSVSLTWLKPEHDGGSRI--VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSE 26442
Query: 199 YYVQVAAQDLTDYGELSDWSLP 220
Y+ +V A++ + + LP
Sbjct: 26443 YFFRVFAENQAGLSDPRELLLP 26464
Score = 30.4 bits (67), Expect = 1.3
Identities = 14/47 (29%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
+TA + GS S+ + + + KP PP V+++ + + + WEPP
Sbjct: 19368 ITAENSSGSKSATIKL--KVLDKPGPPASVKINKMYSDRAMLSWEPP 19412
Score = 30.0 bits (66), Expect = 1.7
Identities = 28/134 (20%), Positives = 49/134 (36%), Gaps = 15/134 (11%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP L + + + R SW +P ++ R G +W +
Sbjct: 15913 GPPKDLKVSDITRGSCRL------SWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVNP 15963
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPF----ITEHIIKPDPPEGVRLS 138
ST+ + D L S Y V A + +G + I PDPP +++
Sbjct: 15964 DCGSTTFVVPD--LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIG 16021
Query: 139 PLAERQLQVQWEPP 152
+ + + + W+PP
Sbjct: 16022 LITKNTVHLSWKPP 16035
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 77 WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFV--PFITEH-IIKPDPPE 133
W + + SC +T +L Y + AV+ +G P + ++ + PD P+
Sbjct: 22684 WTVVDANVQTLSCKVT--KLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK 22741
Query: 134 GVRLSPLAERQLQVQWEPPGS 154
++ + + + V WE P S
Sbjct: 22742 APEVTTVTKDSMIVVWERPAS 22762
Score = 28.9 bits (63), Expect = 3.8
Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 86 STSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII-KPDPPEGVRLSPLAERQ 144
S+ ++T + YV+ T ++ SFV + T +++ KP P +++ ++ +
Sbjct: 18258 SSKFSLTKAKRSDGGKYVVTAT-----NTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 18312
Query: 145 LQVQWEPP 152
V W+PP
Sbjct: 18313 CTVCWDPP 18320
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ + T TS +I + + Y L V+ + S VP + +P PP +R+
Sbjct: 25443 VSSSKTVTSLSIKEASKEDVGTYELCVSN----SAGSITVPITIIVLDRPGPPGPIRIDE 25498
Query: 140 LAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG-PIEATSFILRAVRPRAR 198
++ + + W PP +I + Y + K + +H V + TS + + +
Sbjct: 25499 VSCDSITISWNPPEYDGGCQISN--YIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSE 25556
Query: 199 YYVQVAAQDLTDYGELS 215
Y +V A++ YG+ S
Sbjct: 25557 YQFRVCAEN--RYGKSS 25571
Score = 28.1 bits (61), Expect = 6.5
Identities = 47/207 (22%), Positives = 74/207 (35%), Gaps = 27/207 (13%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAAR-GHSWPCLQ 81
GPP AL + V R VD W PP + P+ Y + R G W
Sbjct: 14185 GPPYALAVVDVTKRH------VDLKWE-PPKNDGGRPIQ---RYVIEKKERLGTRWVKAG 14234
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRL 137
+T C + V A + G S + + I + P PP + +
Sbjct: 14235 KT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHV 14293
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATSF-ILR 191
+ + + + W+PP G P + Y + G ++ RV PI+ F +
Sbjct: 14294 TDAGRKHIAIAWKPPEKNGGSPI-----IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEE 14348
Query: 192 AVRPRARYYVQVAAQDLTDYGELSDWS 218
V P Y ++V A + E S+ S
Sbjct: 14349 GVVPDKEYVLRVRAVNAIGVSEPSEIS 14375
Score = 28.1 bits (61), Expect = 6.5
Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIE- 184
P P + ++ S + + ++ WEPP G P L Y + + G + V E
Sbjct: 14480 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPI-----LHYVLERREAGRRTYIPVMSGEN 14534
Query: 185 ATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
S+ ++ + P Y+ +V A + GE + P A
Sbjct: 14535 KLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 14573
Score = 28.1 bits (61), Expect = 6.5
Identities = 25/121 (20%), Positives = 47/121 (38%), Gaps = 9/121 (7%)
Query: 89 CTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQ 144
CT L Y V A + +G P T +K P PP+ + + + +
Sbjct: 20924 CTYKVTGLSEGCEYFFRVMAENEYGIGE---PTETTEPVKASEAPSPPDSLNIMDITKST 20980
Query: 145 LQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVA 204
+ + W P +I Y I +R+G+ ++ + ++ ++R + Y QV
Sbjct: 20981 VSLAWPKPKHDGGSKITG--YVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 21038
Query: 205 A 205
A
Sbjct: 21039 A 21039
Score = 28.1 bits (61), Expect = 6.5
Identities = 28/133 (21%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 95 QLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQLQVQWE 150
QL Y V A + +G +P T +K P PP + L + + + WE
Sbjct: 22014 QLQEGCSYYFRVLAENEYGIG---LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWE 22070
Query: 151 PPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
P I L Y + + +G+ ++ ++ T + + Y +V+AQ+
Sbjct: 22071 KPEHDGGSRI--LGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKG 22128
Query: 211 YGELSDWSLPATA 223
+ S+P A
Sbjct: 22129 ISDPRQLSVPVIA 22141
Score = 27.7 bits (60), Expect = 8.5
Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 13/116 (11%)
Query: 43 AVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPY 102
+V +W PP + SP++ + ++ + +W + T T+ D L Y
Sbjct: 13503 SVHLTWE-PPDDDGGSPLTGYVVEKREVSRK--TWTKVMDFVTDLEFTVPD--LVQGKEY 13557
Query: 103 VLNVTAVHPWGSSSSFVPFITEHI------IKPDPPEGVRLSPLAERQLQVQWEPP 152
+ V A + G ++ E + PDPPE V+ + + W+PP
Sbjct: 13558 LFKVCARNKCGPGEP--AYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 13611
Score = 27.7 bits (60), Expect = 8.5
Identities = 50/219 (22%), Positives = 79/219 (36%), Gaps = 35/219 (15%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHS-WPCLQ 81
GPP P+V R + SWT PP N SP++ Y L G W +
Sbjct: 15600 GPPGK---PKVLARTKGSMLV---SWT-PPLDNGGSPIT---GYWLEKREEGSPYWSRVS 15649
Query: 82 QTPTSTSCTITDVQ-----LFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPP 132
+ P T + V+ L Y A++ G S S + I P PP
Sbjct: 15650 RAPI-TKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPP 15708
Query: 133 EGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP----IEA 185
+ + + + W+PP G P Y + + +G + RV I
Sbjct: 15709 SCPEVKDKTKSSISLGWKPPAKDGGSPIK-----GYIVEMQEEGTTDWKRVNEPDKLITT 15763
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWS--LPAT 222
++ ++ +Y +V A + E SD + +PAT
Sbjct: 15764 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 15802
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 128 KPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEA 185
+PDPPE ++S + ++ V W PP I Y++ K + + R+ V I
Sbjct: 18398 RPDPPEVTKVS---KEEMTVVWNPPEYDGGKSITG--YFLEKKEKHSTRWVPVNKSAIPE 18452
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
++ + P Y +V A++ GE S S P A
Sbjct: 18453 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 18490
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 42.0 bits (97), Expect = 4e-04
Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 9/112 (8%)
Query: 45 DCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
D WT+P + ++I R R W + T T CT+T + S+ YV
Sbjct: 7796 DLKWTVPEKDGGSPITNYIVEKR---DVRRKGWQTVDTTVKDTKCTVTPLTEGSL--YVF 7850
Query: 105 NVTAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
V A + G S + P PP + + + +R + ++WEPP
Sbjct: 7851 RVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP 7902
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/180 (25%), Positives = 71/180 (39%), Gaps = 8/180 (4%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW PPA + S ++ + A G W + + T+C I V L A Y V
Sbjct: 24438 SWK-PPADDGGSWITNYVVEKCE-AKEGAEWQLVSSAISVTTCRI--VNLTENAGYYFRV 24493
Query: 107 TAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
+A + +G S S V I KP P ++ + + V W+PP S +I +
Sbjct: 24494 SAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRN 24553
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
R K+Q I T F ++ + Y +V ++L E S+ S P T
Sbjct: 24554 YYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT 24613
Score = 37.7 bits (86), Expect = 0.008
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 9/165 (5%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW P + +I R A +W + TS +T+ L Y V
Sbjct: 12413 SWAPPENDGGSQVTHYIVEKR---EADRKTWSTVTPEVKKTSFHVTN--LVPGNEYYFRV 12467
Query: 107 TAVHPWGSS-SSFVP---FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
TAV+ +G + VP ++ + +PDPP + ++ + + + W PP +I
Sbjct: 12468 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12527
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQD 207
R + Q A R+ ++ S ++ ++ +Y +VAA++
Sbjct: 12528 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARN 12572
Score = 37.4 bits (85), Expect = 0.011
Identities = 33/163 (20%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Query: 52 PAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHP 111
PA + P I + M + ++ P ++ TI D + Y++ AV+
Sbjct: 7406 PATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE--AVNV 7463
Query: 112 WGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKR 171
G +++ V + KP PP ++ + + W PP +I Y + +
Sbjct: 7464 CGRATAVVE--VNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI--TNYVVERRA 7519
Query: 172 QGAARFHRV-GPIEATSFILRAVRPRARYYVQVAAQDLTDYGE 213
+ +H++ ++ T+F + P Y +VAA+++ GE
Sbjct: 7520 TDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 7562
Score = 37.0 bits (84), Expect = 0.014
Identities = 47/211 (22%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V V +W P +++ R + R + +
Sbjct: 6887 GPPLNVTITDVN------RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT--AMTV 6938
Query: 83 TPTSTSCTITDV---QLFSMAPYVLNVTAVHPWGSSSSFVPFI--TEHIIKPDPPEGVRL 137
S T+TDV Q +S N V G S+ PF+ + I +P PP +
Sbjct: 6939 RAEDLSATVTDVVEGQEYSFRVRAQNRIGV---GKPSAATPFVKVADPIERPSPPVNLTS 6995
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRA 192
S + +Q++WEPP G P L Y I +G + R + ++ +
Sbjct: 6996 SDQTQSSVQLKWEPPLKDGGSPI-----LGYIIERCEEGKDNWIRCNMKLVPELTYKVTG 7050
Query: 193 VRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ +Y +V+A++ + S+ P TA
Sbjct: 7051 LEKGNKYLYRVSAENKAGVSDPSEILGPLTA 7081
Score = 35.8 bits (81), Expect = 0.031
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLSPLA 141
T + TS + +V + Y L + SS + F+T ++ P PP ++++ +
Sbjct: 16687 TSSFTSLVLDNVNRYDSGKYTLTLE-----NSSGTKSAFVTVRVLDTPSPPVNLKVTEIT 16741
Query: 142 ERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHR--VGPIEATSFILRAVRP 195
+ + + WEPP GS +K +I KR+ + + V S+ + ++
Sbjct: 16742 KDSVSITWEPPLLDGGS-------KIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQE 16794
Query: 196 RARYYVQVAAQDLTDYG 212
YY +V A++ +YG
Sbjct: 16795 GCSYYFRVTAEN--EYG 16809
Score = 35.4 bits (80), Expect = 0.041
Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 27/216 (12%)
Query: 20 GRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC 79
GR GPP + A + + SW P + +++ R A +W
Sbjct: 9910 GRPGPPVG-PIKFESVSADQMTL----SWFPPKDDGGSKITNYVIEKR---EANRKTWVH 9961
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSF--VPFITEHIIK-PDPPEGVR 136
+ P CT T +L YV + A + +G P ++ P P+
Sbjct: 9962 VSSEPKE--CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 10019
Query: 137 LSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEA----TS 187
+S + + V WE P G P YW+ K + R+ RV PI+A S
Sbjct: 10020 VSSVTRNSMTVNWEEPEYDGGSPV-----TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVS 10074
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ + + + Y +V A + G S S PATA
Sbjct: 10075 YKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 10110
Score = 35.4 bits (80), Expect = 0.041
Identities = 31/140 (22%), Positives = 62/140 (44%), Gaps = 21/140 (15%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLS 138
++ T + T + +V F Y+L V SS S F+ ++ P PP+ +++
Sbjct: 15602 IESTSSYTLLIVGNVNRFDSGKYILTVE-----NSSGSKSAFVNVRVLDTPGPPQDLKVK 15656
Query: 139 PLAERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA--TSFILRA 192
+ + + + W+PP GS +K +I KR+ + + TS+ +
Sbjct: 15657 EVTKTSVTLTWDPPLLDGGS-------KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQ 15709
Query: 193 VRPRARYYVQVAAQDLTDYG 212
++ YY +V A++ +YG
Sbjct: 15710 LQEGCSYYFRVLAEN--EYG 15727
Score = 34.7 bits (78), Expect = 0.070
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSF 188
PDPP GV++S ++ + + W P S +I Y + A R+ RVG T +
Sbjct: 24817 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKI--TNYIVEKCATTAERWLRVGQARETRY 24874
Query: 189 ILRAVRPRARYYVQVAAQDLTDYGELSDWSLP 220
+ + + Y +V A++ + S+ S P
Sbjct: 24875 TVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 24906
Score = 34.3 bits (77), Expect = 0.091
Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 10/153 (6%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSS----SSFVPFITEHIIKPDP 131
+W + T T + T+ L Y + A + G +S I E I P+
Sbjct: 10357 AWTPVTYTVTRQNATVQG--LIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 10414
Query: 132 PEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFI 189
PE + + + + + + W PP EI + Y + + G +FH+V + + +
Sbjct: 10415 PEDLEVKEVTKNTVTLTWNPPKYDGGSEI--INYVLESRLIGTEKFHKVTNDNLLSRKYT 10472
Query: 190 LRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
++ ++ Y +V+A ++ G+ S + P T
Sbjct: 10473 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPIT 10505
Score = 33.1 bits (74), Expect = 0.20
Identities = 41/183 (22%), Positives = 75/183 (40%), Gaps = 16/183 (8%)
Query: 46 CSWTL-PPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
CS T PP + S +S + + +W + + S +T +L YV
Sbjct: 17431 CSLTWSPPLQDGGSDISHYVVEKRETSRL--AWTVVASEVVTNSLKVT--KLLEGNEYVF 17486
Query: 105 NVTAVHPWGSSSSF--VPFITEH-IIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIF 161
+ AV+ +G P + ++ + P PP+ + ++ +A+ + V W P S EI
Sbjct: 17487 RIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI- 17545
Query: 162 SLKYWIRYKRQGAARFHRVGPIEATSFILR--AVRPRARYYVQVAAQDLTDYGELSDWSL 219
+ Y + + + R+ + T LR + Y +V+A++ GE S
Sbjct: 17546 -IGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS---- 17600
Query: 220 PAT 222
PAT
Sbjct: 17601 PAT 17603
Score = 33.1 bits (74), Expect = 0.20
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEG-VRLSPLAERQLQVQWEPP 152
+TA + G++ +F+ + + +P PP G V +S + E + ++WEPP
Sbjct: 20244 ITAANSSGTTKAFINIVV--LDRPGPPTGPVVISDITEESVTLKWEPP 20289
Score = 32.3 bits (72), Expect = 0.35
Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 5/126 (3%)
Query: 105 NVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLK 164
++T V+P G + FV + P P +++S + + V W PP + ++
Sbjct: 12372 SLTLVNPAGEKAVFVN--VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQV--TH 12427
Query: 165 YWIRYKRQGAARFHRVGP-IEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
Y + + + V P ++ TSF + + P YY +V A + G +D P A
Sbjct: 12428 YIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA 12487
Query: 224 TMSLGK 229
+ L +
Sbjct: 12488 SDPLSE 12493
Score = 32.3 bits (72), Expect = 0.35
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ TPTS+ TI Y +TA +P+G+ V + P PP V +S
Sbjct: 14123 ITSTPTSSMLTIKYATRKDAGEYT--ITATNPFGTKVEHVKVTVLDV--PGPPGPVEISN 14178
Query: 140 LAERQLQVQWEPP 152
++ + + W PP
Sbjct: 14179 VSAEKATLTWTPP 14191
Score = 32.0 bits (71), Expect = 0.45
Identities = 32/148 (21%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII------KP 129
+W + T T+ IT +L + Y + A + +G S+ P ++ +I +P
Sbjct: 18146 TWHMVSATVARTTIKIT--KLKTGTEYQFRIFAENRYGKSA---PLDSKAVIVQYPFKEP 18200
Query: 130 DPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATS 187
PP ++ +++ Q+ VQW P + +I + Y + K + + + ++ PI+ T
Sbjct: 18201 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKI--IGYHLEQKEKNSILWVKLNKTPIQDTK 18258
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELS 215
F + Y +V+A+++ G+ S
Sbjct: 18259 FKTTGLDEGLEYEFKVSAENIVGIGKPS 18286
Score = 32.0 bits (71), Expect = 0.45
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 85 TSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRLSPL 140
T+T T+T L A Y + A + G S +S + KP P + + +
Sbjct: 24080 TTTMYTVTG--LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSI 24137
Query: 141 AERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRAVRPRAR 198
++ + +QWE P EI L YW+ Y++ G + + + I+ F + +
Sbjct: 24138 SKDSVTLQWEKPECDGGKEI--LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATE 24195
Query: 199 YYVQVAAQDLT 209
Y +V A++ T
Sbjct: 24196 YEFRVFAENET 24206
Score = 31.2 bits (69), Expect = 0.77
Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 14/187 (7%)
Query: 43 AVDCSWTLPPAPNSTSPVS-FIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAP 101
++ SW PP + +P+S ++ R A W + ++ T ++ T +L
Sbjct: 23543 SITISWE-PPELDGGAPLSGYVVEQR---DAHRPGWLPVSESVTRSTFKFT--RLTEGNE 23596
Query: 102 YVLNVTAVHPWGSSSSFVPFITE---HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFP 158
YV V A + +G S + E I P PPE +++ ++ + + W PP
Sbjct: 23597 YVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGS 23656
Query: 159 EIFSLKYWIRYKRQGAARFHRVG--PIEATSFILRAVRPRARYYVQVAAQDLTDYGELSD 216
++ Y + K A R+ RV P+ T + + Y +V A + G+ S
Sbjct: 23657 QVTG--YIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 23714
Query: 217 WSLPATA 223
S P A
Sbjct: 23715 PSKPIVA 23721
Score = 30.8 bits (68), Expect = 1.0
Identities = 43/202 (21%), Positives = 78/202 (38%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV-SFIATYRLGMAARGHSWPCLQ 81
GPP + + V + +WT PP + SP+ S+I R W +
Sbjct: 14169 GPPGPVEISNVSAEKATL------TWT-PPLEDGGSPIKSYILEKR---ETSRLLWTVVS 14218
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSS---SFVPFITEHIIKPDPPEGVRLS 138
+ SC +L Y+ V+AV+ +G S + + P PPE +S
Sbjct: 14219 ED--IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVS 14276
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFILRAVRPR 196
+ + V W+ P EI Y + + + + R+ R P+ + ++
Sbjct: 14277 NVTKNTATVSWKRPVDDGGSEITG--YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14334
Query: 197 ARYYVQVAAQDLTDYGELSDWS 218
+ Y +V+A++ G S+ S
Sbjct: 14335 STYEFRVSAENRAGIGPPSEAS 14356
Score = 30.8 bits (68), Expect = 1.0
Identities = 37/202 (18%), Positives = 80/202 (39%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V ++ SW +P ++ R A +W +
Sbjct: 19974 GPPTNITVQDVTKESAVL------SWDVPENDGGAPVKNYHIEKR---EASKKAWVSVTN 20024
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLS 138
S +T++Q A Y V+ + +G +P T+ +K P PPE + ++
Sbjct: 20025 NCNRLSYKVTNLQ--EGAIYYFRVSGENEFGVG---IPAETKEGVKITEKPSPPEKLGVT 20079
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRAR 198
+++ + + W P I + Y + +G + + ++T ++ +R +
Sbjct: 20080 SISKDSVSLTWLKPEHDGGSRI--VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSE 20137
Query: 199 YYVQVAAQDLTDYGELSDWSLP 220
Y+ +V A++ + + LP
Sbjct: 20138 YFFRVFAENQAGLSDPRELLLP 20159
Score = 30.4 bits (67), Expect = 1.3
Identities = 14/47 (29%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
+TA + GS S+ + + + KP PP V+++ + + + WEPP
Sbjct: 13063 ITAENSSGSKSATIKL--KVLDKPGPPASVKINKMYSDRAMLSWEPP 13107
Score = 30.0 bits (66), Expect = 1.7
Identities = 28/134 (20%), Positives = 49/134 (36%), Gaps = 15/134 (11%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP L + + + R SW +P ++ R G +W +
Sbjct: 9608 GPPKDLKVSDITRGSCRL------SWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVNP 9658
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPF----ITEHIIKPDPPEGVRLS 138
ST+ + D L S Y V A + +G + I PDPP +++
Sbjct: 9659 DCGSTTFVVPD--LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIG 9716
Query: 139 PLAERQLQVQWEPP 152
+ + + + W+PP
Sbjct: 9717 LITKNTVHLSWKPP 9730
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 77 WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFV--PFITEH-IIKPDPPE 133
W + + SC +T +L Y + AV+ +G P + ++ + PD P+
Sbjct: 16379 WTVVDANVQTLSCKVT--KLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK 16436
Query: 134 GVRLSPLAERQLQVQWEPPGS 154
++ + + + V WE P S
Sbjct: 16437 APEVTTVTKDSMIVVWERPAS 16457
Score = 28.9 bits (63), Expect = 3.8
Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 86 STSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII-KPDPPEGVRLSPLAERQ 144
S+ ++T + YV+ T ++ SFV + T +++ KP P +++ ++ +
Sbjct: 11953 SSKFSLTKAKRSDGGKYVVTAT-----NTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 12007
Query: 145 LQVQWEPP 152
V W+PP
Sbjct: 12008 CTVCWDPP 12015
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ + T TS +I + + Y L V+ + S VP + +P PP +R+
Sbjct: 19138 VSSSKTVTSLSIKEASKEDVGTYELCVSN----SAGSITVPITIIVLDRPGPPGPIRIDE 19193
Query: 140 LAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG-PIEATSFILRAVRPRAR 198
++ + + W PP +I + Y + K + +H V + TS + + +
Sbjct: 19194 VSCDSITISWNPPEYDGGCQISN--YIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSE 19251
Query: 199 YYVQVAAQDLTDYGELS 215
Y +V A++ YG+ S
Sbjct: 19252 YQFRVCAEN--RYGKSS 19266
Score = 28.1 bits (61), Expect = 6.5
Identities = 47/207 (22%), Positives = 74/207 (35%), Gaps = 27/207 (13%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAAR-GHSWPCLQ 81
GPP AL + V R VD W PP + P+ Y + R G W
Sbjct: 7880 GPPYALAVVDVTKRH------VDLKWE-PPKNDGGRPIQ---RYVIEKKERLGTRWVKAG 7929
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRL 137
+T C + V A + G S + + I + P PP + +
Sbjct: 7930 KT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHV 7988
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATSF-ILR 191
+ + + + W+PP G P + Y + G ++ RV PI+ F +
Sbjct: 7989 TDAGRKHIAIAWKPPEKNGGSPI-----IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEE 8043
Query: 192 AVRPRARYYVQVAAQDLTDYGELSDWS 218
V P Y ++V A + E S+ S
Sbjct: 8044 GVVPDKEYVLRVRAVNAIGVSEPSEIS 8070
Score = 28.1 bits (61), Expect = 6.5
Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIE- 184
P P + ++ S + + ++ WEPP G P L Y + + G + V E
Sbjct: 8175 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPI-----LHYVLERREAGRRTYIPVMSGEN 8229
Query: 185 ATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
S+ ++ + P Y+ +V A + GE + P A
Sbjct: 8230 KLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8268
Score = 28.1 bits (61), Expect = 6.5
Identities = 25/121 (20%), Positives = 47/121 (38%), Gaps = 9/121 (7%)
Query: 89 CTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQ 144
CT L Y V A + +G P T +K P PP+ + + + +
Sbjct: 14619 CTYKVTGLSEGCEYFFRVMAENEYGIGE---PTETTEPVKASEAPSPPDSLNIMDITKST 14675
Query: 145 LQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVA 204
+ + W P +I Y I +R+G+ ++ + ++ ++R + Y QV
Sbjct: 14676 VSLAWPKPKHDGGSKITG--YVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14733
Query: 205 A 205
A
Sbjct: 14734 A 14734
Score = 28.1 bits (61), Expect = 6.5
Identities = 28/133 (21%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 95 QLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQLQVQWE 150
QL Y V A + +G +P T +K P PP + L + + + WE
Sbjct: 15709 QLQEGCSYYFRVLAENEYGIG---LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWE 15765
Query: 151 PPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
P I L Y + + +G+ ++ ++ T + + Y +V+AQ+
Sbjct: 15766 KPEHDGGSRI--LGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKG 15823
Query: 211 YGELSDWSLPATA 223
+ S+P A
Sbjct: 15824 ISDPRQLSVPVIA 15836
Score = 27.7 bits (60), Expect = 8.5
Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 13/116 (11%)
Query: 43 AVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPY 102
+V +W PP + SP++ + ++ + +W + T T+ D L Y
Sbjct: 7198 SVHLTWE-PPDDDGGSPLTGYVVEKREVSRK--TWTKVMDFVTDLEFTVPD--LVQGKEY 7252
Query: 103 VLNVTAVHPWGSSSSFVPFITEHI------IKPDPPEGVRLSPLAERQLQVQWEPP 152
+ V A + G ++ E + PDPPE V+ + + W+PP
Sbjct: 7253 LFKVCARNKCGPGEP--AYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7306
Score = 27.7 bits (60), Expect = 8.5
Identities = 50/219 (22%), Positives = 79/219 (36%), Gaps = 35/219 (15%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHS-WPCLQ 81
GPP P+V R + SWT PP N SP++ Y L G W +
Sbjct: 9295 GPPGK---PKVLARTKGSMLV---SWT-PPLDNGGSPIT---GYWLEKREEGSPYWSRVS 9344
Query: 82 QTPTSTSCTITDVQ-----LFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPP 132
+ P T + V+ L Y A++ G S S + I P PP
Sbjct: 9345 RAPI-TKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPP 9403
Query: 133 EGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP----IEA 185
+ + + + W+PP G P Y + + +G + RV I
Sbjct: 9404 SCPEVKDKTKSSISLGWKPPAKDGGSPIK-----GYIVEMQEEGTTDWKRVNEPDKLITT 9458
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWS--LPAT 222
++ ++ +Y +V A + E SD + +PAT
Sbjct: 9459 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 9497
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 128 KPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEA 185
+PDPPE ++S + ++ V W PP I Y++ K + + R+ V I
Sbjct: 12093 RPDPPEVTKVS---KEEMTVVWNPPEYDGGKSITG--YFLEKKEKHSTRWVPVNKSAIPE 12147
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
++ + P Y +V A++ GE S S P A
Sbjct: 12148 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12185
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 42.0 bits (97), Expect = 4e-04
Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 9/112 (8%)
Query: 45 DCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
D WT+P + ++I R R W + T T CT+T + S+ YV
Sbjct: 7729 DLKWTVPEKDGGSPITNYIVEKR---DVRRKGWQTVDTTVKDTKCTVTPLTEGSL--YVF 7783
Query: 105 NVTAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
V A + G S + P PP + + + +R + ++WEPP
Sbjct: 7784 RVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP 7835
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/180 (25%), Positives = 71/180 (39%), Gaps = 8/180 (4%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW PPA + S ++ + A G W + + T+C I V L A Y V
Sbjct: 24371 SWK-PPADDGGSWITNYVVEKCE-AKEGAEWQLVSSAISVTTCRI--VNLTENAGYYFRV 24426
Query: 107 TAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
+A + +G S S V I KP P ++ + + V W+PP S +I +
Sbjct: 24427 SAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRN 24486
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
R K+Q I T F ++ + Y +V ++L E S+ S P T
Sbjct: 24487 YYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT 24546
Score = 37.7 bits (86), Expect = 0.008
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 9/165 (5%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW P + +I R A +W + TS +T+ L Y V
Sbjct: 12346 SWAPPENDGGSQVTHYIVEKR---EADRKTWSTVTPEVKKTSFHVTN--LVPGNEYYFRV 12400
Query: 107 TAVHPWGSS-SSFVP---FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
TAV+ +G + VP ++ + +PDPP + ++ + + + W PP +I
Sbjct: 12401 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12460
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQD 207
R + Q A R+ ++ S ++ ++ +Y +VAA++
Sbjct: 12461 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARN 12505
Score = 37.4 bits (85), Expect = 0.011
Identities = 33/163 (20%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Query: 52 PAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHP 111
PA + P I + M + ++ P ++ TI D + Y++ AV+
Sbjct: 7339 PATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE--AVNV 7396
Query: 112 WGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKR 171
G +++ V + KP PP ++ + + W PP +I Y + +
Sbjct: 7397 CGRATAVVE--VNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI--TNYVVERRA 7452
Query: 172 QGAARFHRV-GPIEATSFILRAVRPRARYYVQVAAQDLTDYGE 213
+ +H++ ++ T+F + P Y +VAA+++ GE
Sbjct: 7453 TDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 7495
Score = 37.0 bits (84), Expect = 0.014
Identities = 47/211 (22%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V V +W P +++ R + R + +
Sbjct: 6820 GPPLNVTITDVN------RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT--AMTV 6871
Query: 83 TPTSTSCTITDV---QLFSMAPYVLNVTAVHPWGSSSSFVPFI--TEHIIKPDPPEGVRL 137
S T+TDV Q +S N V G S+ PF+ + I +P PP +
Sbjct: 6872 RAEDLSATVTDVVEGQEYSFRVRAQNRIGV---GKPSAATPFVKVADPIERPSPPVNLTS 6928
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRA 192
S + +Q++WEPP G P L Y I +G + R + ++ +
Sbjct: 6929 SDQTQSSVQLKWEPPLKDGGSPI-----LGYIIERCEEGKDNWIRCNMKLVPELTYKVTG 6983
Query: 193 VRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ +Y +V+A++ + S+ P TA
Sbjct: 6984 LEKGNKYLYRVSAENKAGVSDPSEILGPLTA 7014
Score = 35.8 bits (81), Expect = 0.031
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLSPLA 141
T + TS + +V + Y L + SS + F+T ++ P PP ++++ +
Sbjct: 16620 TSSFTSLVLDNVNRYDSGKYTLTLE-----NSSGTKSAFVTVRVLDTPSPPVNLKVTEIT 16674
Query: 142 ERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHR--VGPIEATSFILRAVRP 195
+ + + WEPP GS +K +I KR+ + + V S+ + ++
Sbjct: 16675 KDSVSITWEPPLLDGGS-------KIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQE 16727
Query: 196 RARYYVQVAAQDLTDYG 212
YY +V A++ +YG
Sbjct: 16728 GCSYYFRVTAEN--EYG 16742
Score = 35.4 bits (80), Expect = 0.041
Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 27/216 (12%)
Query: 20 GRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC 79
GR GPP + A + + SW P + +++ R A +W
Sbjct: 9843 GRPGPPVG-PIKFESVSADQMTL----SWFPPKDDGGSKITNYVIEKR---EANRKTWVH 9894
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSF--VPFITEHIIK-PDPPEGVR 136
+ P CT T +L YV + A + +G P ++ P P+
Sbjct: 9895 VSSEPKE--CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 9952
Query: 137 LSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEA----TS 187
+S + + V WE P G P YW+ K + R+ RV PI+A S
Sbjct: 9953 VSSVTRNSMTVNWEEPEYDGGSPV-----TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVS 10007
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ + + + Y +V A + G S S PATA
Sbjct: 10008 YKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 10043
Score = 35.4 bits (80), Expect = 0.041
Identities = 31/140 (22%), Positives = 62/140 (44%), Gaps = 21/140 (15%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLS 138
++ T + T + +V F Y+L V SS S F+ ++ P PP+ +++
Sbjct: 15535 IESTSSYTLLIVGNVNRFDSGKYILTVE-----NSSGSKSAFVNVRVLDTPGPPQDLKVK 15589
Query: 139 PLAERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA--TSFILRA 192
+ + + + W+PP GS +K +I KR+ + + TS+ +
Sbjct: 15590 EVTKTSVTLTWDPPLLDGGS-------KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQ 15642
Query: 193 VRPRARYYVQVAAQDLTDYG 212
++ YY +V A++ +YG
Sbjct: 15643 LQEGCSYYFRVLAEN--EYG 15660
Score = 34.7 bits (78), Expect = 0.070
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSF 188
PDPP GV++S ++ + + W P S +I Y + A R+ RVG T +
Sbjct: 24750 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKI--TNYIVEKCATTAERWLRVGQARETRY 24807
Query: 189 ILRAVRPRARYYVQVAAQDLTDYGELSDWSLP 220
+ + + Y +V A++ + S+ S P
Sbjct: 24808 TVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 24839
Score = 34.3 bits (77), Expect = 0.091
Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 10/153 (6%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSS----SSFVPFITEHIIKPDP 131
+W + T T + T+ L Y + A + G +S I E I P+
Sbjct: 10290 AWTPVTYTVTRQNATVQG--LIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 10347
Query: 132 PEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFI 189
PE + + + + + + W PP EI + Y + + G +FH+V + + +
Sbjct: 10348 PEDLEVKEVTKNTVTLTWNPPKYDGGSEI--INYVLESRLIGTEKFHKVTNDNLLSRKYT 10405
Query: 190 LRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
++ ++ Y +V+A ++ G+ S + P T
Sbjct: 10406 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPIT 10438
Score = 33.1 bits (74), Expect = 0.20
Identities = 41/183 (22%), Positives = 75/183 (40%), Gaps = 16/183 (8%)
Query: 46 CSWTL-PPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
CS T PP + S +S + + +W + + S +T +L YV
Sbjct: 17364 CSLTWSPPLQDGGSDISHYVVEKRETSRL--AWTVVASEVVTNSLKVT--KLLEGNEYVF 17419
Query: 105 NVTAVHPWGSSSSF--VPFITEH-IIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIF 161
+ AV+ +G P + ++ + P PP+ + ++ +A+ + V W P S EI
Sbjct: 17420 RIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI- 17478
Query: 162 SLKYWIRYKRQGAARFHRVGPIEATSFILR--AVRPRARYYVQVAAQDLTDYGELSDWSL 219
+ Y + + + R+ + T LR + Y +V+A++ GE S
Sbjct: 17479 -IGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS---- 17533
Query: 220 PAT 222
PAT
Sbjct: 17534 PAT 17536
Score = 33.1 bits (74), Expect = 0.20
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEG-VRLSPLAERQLQVQWEPP 152
+TA + G++ +F+ + + +P PP G V +S + E + ++WEPP
Sbjct: 20177 ITAANSSGTTKAFINIVV--LDRPGPPTGPVVISDITEESVTLKWEPP 20222
Score = 32.3 bits (72), Expect = 0.35
Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 5/126 (3%)
Query: 105 NVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLK 164
++T V+P G + FV + P P +++S + + V W PP + ++
Sbjct: 12305 SLTLVNPAGEKAVFVN--VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQV--TH 12360
Query: 165 YWIRYKRQGAARFHRVGP-IEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
Y + + + V P ++ TSF + + P YY +V A + G +D P A
Sbjct: 12361 YIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA 12420
Query: 224 TMSLGK 229
+ L +
Sbjct: 12421 SDPLSE 12426
Score = 32.3 bits (72), Expect = 0.35
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ TPTS+ TI Y +TA +P+G+ V + P PP V +S
Sbjct: 14056 ITSTPTSSMLTIKYATRKDAGEYT--ITATNPFGTKVEHVKVTVLDV--PGPPGPVEISN 14111
Query: 140 LAERQLQVQWEPP 152
++ + + W PP
Sbjct: 14112 VSAEKATLTWTPP 14124
Score = 32.0 bits (71), Expect = 0.45
Identities = 32/148 (21%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII------KP 129
+W + T T+ IT +L + Y + A + +G S+ P ++ +I +P
Sbjct: 18079 TWHMVSATVARTTIKIT--KLKTGTEYQFRIFAENRYGKSA---PLDSKAVIVQYPFKEP 18133
Query: 130 DPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATS 187
PP ++ +++ Q+ VQW P + +I + Y + K + + + ++ PI+ T
Sbjct: 18134 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKI--IGYHLEQKEKNSILWVKLNKTPIQDTK 18191
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELS 215
F + Y +V+A+++ G+ S
Sbjct: 18192 FKTTGLDEGLEYEFKVSAENIVGIGKPS 18219
Score = 32.0 bits (71), Expect = 0.45
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 85 TSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRLSPL 140
T+T T+T L A Y + A + G S +S + KP P + + +
Sbjct: 24013 TTTMYTVTG--LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSI 24070
Query: 141 AERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRAVRPRAR 198
++ + +QWE P EI L YW+ Y++ G + + + I+ F + +
Sbjct: 24071 SKDSVTLQWEKPECDGGKEI--LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATE 24128
Query: 199 YYVQVAAQDLT 209
Y +V A++ T
Sbjct: 24129 YEFRVFAENET 24139
Score = 31.2 bits (69), Expect = 0.77
Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 14/187 (7%)
Query: 43 AVDCSWTLPPAPNSTSPVS-FIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAP 101
++ SW PP + +P+S ++ R A W + ++ T ++ T +L
Sbjct: 23476 SITISWE-PPELDGGAPLSGYVVEQR---DAHRPGWLPVSESVTRSTFKFT--RLTEGNE 23529
Query: 102 YVLNVTAVHPWGSSSSFVPFITE---HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFP 158
YV V A + +G S + E I P PPE +++ ++ + + W PP
Sbjct: 23530 YVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGS 23589
Query: 159 EIFSLKYWIRYKRQGAARFHRVG--PIEATSFILRAVRPRARYYVQVAAQDLTDYGELSD 216
++ Y + K A R+ RV P+ T + + Y +V A + G+ S
Sbjct: 23590 QVTG--YIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 23647
Query: 217 WSLPATA 223
S P A
Sbjct: 23648 PSKPIVA 23654
Score = 30.8 bits (68), Expect = 1.0
Identities = 43/202 (21%), Positives = 78/202 (38%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV-SFIATYRLGMAARGHSWPCLQ 81
GPP + + V + +WT PP + SP+ S+I R W +
Sbjct: 14102 GPPGPVEISNVSAEKATL------TWT-PPLEDGGSPIKSYILEKR---ETSRLLWTVVS 14151
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSS---SFVPFITEHIIKPDPPEGVRLS 138
+ SC +L Y+ V+AV+ +G S + + P PPE +S
Sbjct: 14152 ED--IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVS 14209
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFILRAVRPR 196
+ + V W+ P EI Y + + + + R+ R P+ + ++
Sbjct: 14210 NVTKNTATVSWKRPVDDGGSEITG--YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14267
Query: 197 ARYYVQVAAQDLTDYGELSDWS 218
+ Y +V+A++ G S+ S
Sbjct: 14268 STYEFRVSAENRAGIGPPSEAS 14289
Score = 30.8 bits (68), Expect = 1.0
Identities = 37/202 (18%), Positives = 80/202 (39%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V ++ SW +P ++ R A +W +
Sbjct: 19907 GPPTNITVQDVTKESAVL------SWDVPENDGGAPVKNYHIEKR---EASKKAWVSVTN 19957
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLS 138
S +T++Q A Y V+ + +G +P T+ +K P PPE + ++
Sbjct: 19958 NCNRLSYKVTNLQ--EGAIYYFRVSGENEFGVG---IPAETKEGVKITEKPSPPEKLGVT 20012
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRAR 198
+++ + + W P I + Y + +G + + ++T ++ +R +
Sbjct: 20013 SISKDSVSLTWLKPEHDGGSRI--VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSE 20070
Query: 199 YYVQVAAQDLTDYGELSDWSLP 220
Y+ +V A++ + + LP
Sbjct: 20071 YFFRVFAENQAGLSDPRELLLP 20092
Score = 30.4 bits (67), Expect = 1.3
Identities = 14/47 (29%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
+TA + GS S+ + + + KP PP V+++ + + + WEPP
Sbjct: 12996 ITAENSSGSKSATIKL--KVLDKPGPPASVKINKMYSDRAMLSWEPP 13040
Score = 30.0 bits (66), Expect = 1.7
Identities = 28/134 (20%), Positives = 49/134 (36%), Gaps = 15/134 (11%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP L + + + R SW +P ++ R G +W +
Sbjct: 9541 GPPKDLKVSDITRGSCRL------SWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVNP 9591
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPF----ITEHIIKPDPPEGVRLS 138
ST+ + D L S Y V A + +G + I PDPP +++
Sbjct: 9592 DCGSTTFVVPD--LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIG 9649
Query: 139 PLAERQLQVQWEPP 152
+ + + + W+PP
Sbjct: 9650 LITKNTVHLSWKPP 9663
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 77 WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFV--PFITEH-IIKPDPPE 133
W + + SC +T +L Y + AV+ +G P + ++ + PD P+
Sbjct: 16312 WTVVDANVQTLSCKVT--KLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK 16369
Query: 134 GVRLSPLAERQLQVQWEPPGS 154
++ + + + V WE P S
Sbjct: 16370 APEVTTVTKDSMIVVWERPAS 16390
Score = 28.9 bits (63), Expect = 3.8
Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 86 STSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII-KPDPPEGVRLSPLAERQ 144
S+ ++T + YV+ T ++ SFV + T +++ KP P +++ ++ +
Sbjct: 11886 SSKFSLTKAKRSDGGKYVVTAT-----NTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11940
Query: 145 LQVQWEPP 152
V W+PP
Sbjct: 11941 CTVCWDPP 11948
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ + T TS +I + + Y L V+ + S VP + +P PP +R+
Sbjct: 19071 VSSSKTVTSLSIKEASKEDVGTYELCVSN----SAGSITVPITIIVLDRPGPPGPIRIDE 19126
Query: 140 LAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG-PIEATSFILRAVRPRAR 198
++ + + W PP +I + Y + K + +H V + TS + + +
Sbjct: 19127 VSCDSITISWNPPEYDGGCQISN--YIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSE 19184
Query: 199 YYVQVAAQDLTDYGELS 215
Y +V A++ YG+ S
Sbjct: 19185 YQFRVCAEN--RYGKSS 19199
Score = 28.1 bits (61), Expect = 6.5
Identities = 47/207 (22%), Positives = 74/207 (35%), Gaps = 27/207 (13%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAAR-GHSWPCLQ 81
GPP AL + V R VD W PP + P+ Y + R G W
Sbjct: 7813 GPPYALAVVDVTKRH------VDLKWE-PPKNDGGRPIQ---RYVIEKKERLGTRWVKAG 7862
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRL 137
+T C + V A + G S + + I + P PP + +
Sbjct: 7863 KT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHV 7921
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATSF-ILR 191
+ + + + W+PP G P + Y + G ++ RV PI+ F +
Sbjct: 7922 TDAGRKHIAIAWKPPEKNGGSPI-----IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEE 7976
Query: 192 AVRPRARYYVQVAAQDLTDYGELSDWS 218
V P Y ++V A + E S+ S
Sbjct: 7977 GVVPDKEYVLRVRAVNAIGVSEPSEIS 8003
Score = 28.1 bits (61), Expect = 6.5
Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIE- 184
P P + ++ S + + ++ WEPP G P L Y + + G + V E
Sbjct: 8108 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPI-----LHYVLERREAGRRTYIPVMSGEN 8162
Query: 185 ATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
S+ ++ + P Y+ +V A + GE + P A
Sbjct: 8163 KLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8201
Score = 28.1 bits (61), Expect = 6.5
Identities = 25/121 (20%), Positives = 47/121 (38%), Gaps = 9/121 (7%)
Query: 89 CTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQ 144
CT L Y V A + +G P T +K P PP+ + + + +
Sbjct: 14552 CTYKVTGLSEGCEYFFRVMAENEYGIGE---PTETTEPVKASEAPSPPDSLNIMDITKST 14608
Query: 145 LQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVA 204
+ + W P +I Y I +R+G+ ++ + ++ ++R + Y QV
Sbjct: 14609 VSLAWPKPKHDGGSKITG--YVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14666
Query: 205 A 205
A
Sbjct: 14667 A 14667
Score = 28.1 bits (61), Expect = 6.5
Identities = 28/133 (21%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 95 QLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQLQVQWE 150
QL Y V A + +G +P T +K P PP + L + + + WE
Sbjct: 15642 QLQEGCSYYFRVLAENEYGIG---LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWE 15698
Query: 151 PPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
P I L Y + + +G+ ++ ++ T + + Y +V+AQ+
Sbjct: 15699 KPEHDGGSRI--LGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKG 15756
Query: 211 YGELSDWSLPATA 223
+ S+P A
Sbjct: 15757 ISDPRQLSVPVIA 15769
Score = 27.7 bits (60), Expect = 8.5
Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 13/116 (11%)
Query: 43 AVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPY 102
+V +W PP + SP++ + ++ + +W + T T+ D L Y
Sbjct: 7131 SVHLTWE-PPDDDGGSPLTGYVVEKREVSRK--TWTKVMDFVTDLEFTVPD--LVQGKEY 7185
Query: 103 VLNVTAVHPWGSSSSFVPFITEHI------IKPDPPEGVRLSPLAERQLQVQWEPP 152
+ V A + G ++ E + PDPPE V+ + + W+PP
Sbjct: 7186 LFKVCARNKCGPGEP--AYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7239
Score = 27.7 bits (60), Expect = 8.5
Identities = 50/219 (22%), Positives = 79/219 (36%), Gaps = 35/219 (15%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHS-WPCLQ 81
GPP P+V R + SWT PP N SP++ Y L G W +
Sbjct: 9228 GPPGK---PKVLARTKGSMLV---SWT-PPLDNGGSPIT---GYWLEKREEGSPYWSRVS 9277
Query: 82 QTPTSTSCTITDVQ-----LFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPP 132
+ P T + V+ L Y A++ G S S + I P PP
Sbjct: 9278 RAPI-TKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPP 9336
Query: 133 EGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP----IEA 185
+ + + + W+PP G P Y + + +G + RV I
Sbjct: 9337 SCPEVKDKTKSSISLGWKPPAKDGGSPIK-----GYIVEMQEEGTTDWKRVNEPDKLITT 9391
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWS--LPAT 222
++ ++ +Y +V A + E SD + +PAT
Sbjct: 9392 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 9430
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 128 KPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEA 185
+PDPPE ++S + ++ V W PP I Y++ K + + R+ V I
Sbjct: 12026 RPDPPEVTKVS---KEEMTVVWNPPEYDGGKSITG--YFLEKKEKHSTRWVPVNKSAIPE 12080
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
++ + P Y +V A++ GE S S P A
Sbjct: 12081 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12118
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 42.0 bits (97), Expect = 4e-04
Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 9/112 (8%)
Query: 45 DCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
D WT+P + ++I R R W + T T CT+T + S+ YV
Sbjct: 7604 DLKWTVPEKDGGSPITNYIVEKR---DVRRKGWQTVDTTVKDTKCTVTPLTEGSL--YVF 7658
Query: 105 NVTAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
V A + G S + P PP + + + +R + ++WEPP
Sbjct: 7659 RVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP 7710
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/180 (25%), Positives = 71/180 (39%), Gaps = 8/180 (4%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW PPA + S ++ + A G W + + T+C I V L A Y V
Sbjct: 24246 SWK-PPADDGGSWITNYVVEKCE-AKEGAEWQLVSSAISVTTCRI--VNLTENAGYYFRV 24301
Query: 107 TAVHPWGSSS----SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
+A + +G S S V I KP P ++ + + V W+PP S +I +
Sbjct: 24302 SAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRN 24361
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
R K+Q I T F ++ + Y +V ++L E S+ S P T
Sbjct: 24362 YYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT 24421
Score = 37.7 bits (86), Expect = 0.008
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 9/165 (5%)
Query: 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
SW P + +I R A +W + TS +T+ L Y V
Sbjct: 12221 SWAPPENDGGSQVTHYIVEKR---EADRKTWSTVTPEVKKTSFHVTN--LVPGNEYYFRV 12275
Query: 107 TAVHPWGSS-SSFVP---FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFS 162
TAV+ +G + VP ++ + +PDPP + ++ + + + W PP +I
Sbjct: 12276 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12335
Query: 163 LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQD 207
R + Q A R+ ++ S ++ ++ +Y +VAA++
Sbjct: 12336 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARN 12380
Score = 37.4 bits (85), Expect = 0.011
Identities = 33/163 (20%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Query: 52 PAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHP 111
PA + P I + M + ++ P ++ TI D + Y++ AV+
Sbjct: 7214 PATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE--AVNV 7271
Query: 112 WGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKR 171
G +++ V + KP PP ++ + + W PP +I Y + +
Sbjct: 7272 CGRATAVVE--VNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI--TNYVVERRA 7327
Query: 172 QGAARFHRV-GPIEATSFILRAVRPRARYYVQVAAQDLTDYGE 213
+ +H++ ++ T+F + P Y +VAA+++ GE
Sbjct: 7328 TDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 7370
Score = 37.0 bits (84), Expect = 0.014
Identities = 47/211 (22%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V V +W P +++ R + R + +
Sbjct: 6695 GPPLNVTITDVN------RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT--AMTV 6746
Query: 83 TPTSTSCTITDV---QLFSMAPYVLNVTAVHPWGSSSSFVPFI--TEHIIKPDPPEGVRL 137
S T+TDV Q +S N V G S+ PF+ + I +P PP +
Sbjct: 6747 RAEDLSATVTDVVEGQEYSFRVRAQNRIGV---GKPSAATPFVKVADPIERPSPPVNLTS 6803
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRA 192
S + +Q++WEPP G P L Y I +G + R + ++ +
Sbjct: 6804 SDQTQSSVQLKWEPPLKDGGSPI-----LGYIIERCEEGKDNWIRCNMKLVPELTYKVTG 6858
Query: 193 VRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ +Y +V+A++ + S+ P TA
Sbjct: 6859 LEKGNKYLYRVSAENKAGVSDPSEILGPLTA 6889
Score = 35.8 bits (81), Expect = 0.031
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLSPLA 141
T + TS + +V + Y L + SS + F+T ++ P PP ++++ +
Sbjct: 16495 TSSFTSLVLDNVNRYDSGKYTLTLE-----NSSGTKSAFVTVRVLDTPSPPVNLKVTEIT 16549
Query: 142 ERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHR--VGPIEATSFILRAVRP 195
+ + + WEPP GS +K +I KR+ + + V S+ + ++
Sbjct: 16550 KDSVSITWEPPLLDGGS-------KIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQE 16602
Query: 196 RARYYVQVAAQDLTDYG 212
YY +V A++ +YG
Sbjct: 16603 GCSYYFRVTAEN--EYG 16617
Score = 35.4 bits (80), Expect = 0.041
Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 27/216 (12%)
Query: 20 GRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC 79
GR GPP + A + + SW P + +++ R A +W
Sbjct: 9718 GRPGPPVG-PIKFESVSADQMTL----SWFPPKDDGGSKITNYVIEKR---EANRKTWVH 9769
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSF--VPFITEHIIK-PDPPEGVR 136
+ P CT T +L YV + A + +G P ++ P P+
Sbjct: 9770 VSSEPKE--CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 9827
Query: 137 LSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEA----TS 187
+S + + V WE P G P YW+ K + R+ RV PI+A S
Sbjct: 9828 VSSVTRNSMTVNWEEPEYDGGSPV-----TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVS 9882
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
+ + + + Y +V A + G S S PATA
Sbjct: 9883 YKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATA 9918
Score = 35.4 bits (80), Expect = 0.041
Identities = 31/140 (22%), Positives = 62/140 (44%), Gaps = 21/140 (15%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK-PDPPEGVRLS 138
++ T + T + +V F Y+L V SS S F+ ++ P PP+ +++
Sbjct: 15410 IESTSSYTLLIVGNVNRFDSGKYILTVE-----NSSGSKSAFVNVRVLDTPGPPQDLKVK 15464
Query: 139 PLAERQLQVQWEPP----GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA--TSFILRA 192
+ + + + W+PP GS +K +I KR+ + + TS+ +
Sbjct: 15465 EVTKTSVTLTWDPPLLDGGS-------KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQ 15517
Query: 193 VRPRARYYVQVAAQDLTDYG 212
++ YY +V A++ +YG
Sbjct: 15518 LQEGCSYYFRVLAEN--EYG 15535
Score = 34.7 bits (78), Expect = 0.070
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSF 188
PDPP GV++S ++ + + W P S +I Y + A R+ RVG T +
Sbjct: 24625 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKI--TNYIVEKCATTAERWLRVGQARETRY 24682
Query: 189 ILRAVRPRARYYVQVAAQDLTDYGELSDWSLP 220
+ + + Y +V A++ + S+ S P
Sbjct: 24683 TVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 24714
Score = 34.3 bits (77), Expect = 0.091
Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 10/153 (6%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSS----SSFVPFITEHIIKPDP 131
+W + T T + T+ L Y + A + G +S I E I P+
Sbjct: 10165 AWTPVTYTVTRQNATVQG--LIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER 10222
Query: 132 PEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFI 189
PE + + + + + + W PP EI + Y + + G +FH+V + + +
Sbjct: 10223 PEDLEVKEVTKNTVTLTWNPPKYDGGSEI--INYVLESRLIGTEKFHKVTNDNLLSRKYT 10280
Query: 190 LRAVRPRARYYVQVAAQDLTDYGELSDWSLPAT 222
++ ++ Y +V+A ++ G+ S + P T
Sbjct: 10281 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPIT 10313
Score = 33.1 bits (74), Expect = 0.20
Identities = 41/183 (22%), Positives = 75/183 (40%), Gaps = 16/183 (8%)
Query: 46 CSWTL-PPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVL 104
CS T PP + S +S + + +W + + S +T +L YV
Sbjct: 17239 CSLTWSPPLQDGGSDISHYVVEKRETSRL--AWTVVASEVVTNSLKVT--KLLEGNEYVF 17294
Query: 105 NVTAVHPWGSSSSF--VPFITEH-IIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIF 161
+ AV+ +G P + ++ + P PP+ + ++ +A+ + V W P S EI
Sbjct: 17295 RIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI- 17353
Query: 162 SLKYWIRYKRQGAARFHRVGPIEATSFILR--AVRPRARYYVQVAAQDLTDYGELSDWSL 219
+ Y + + + R+ + T LR + Y +V+A++ GE S
Sbjct: 17354 -IGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS---- 17408
Query: 220 PAT 222
PAT
Sbjct: 17409 PAT 17411
Score = 33.1 bits (74), Expect = 0.20
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEG-VRLSPLAERQLQVQWEPP 152
+TA + G++ +F+ + + +P PP G V +S + E + ++WEPP
Sbjct: 20052 ITAANSSGTTKAFINIVV--LDRPGPPTGPVVISDITEESVTLKWEPP 20097
Score = 32.3 bits (72), Expect = 0.35
Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 5/126 (3%)
Query: 105 NVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLK 164
++T V+P G + FV + P P +++S + + V W PP + ++
Sbjct: 12180 SLTLVNPAGEKAVFVN--VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQV--TH 12235
Query: 165 YWIRYKRQGAARFHRVGP-IEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
Y + + + V P ++ TSF + + P YY +V A + G +D P A
Sbjct: 12236 YIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA 12295
Query: 224 TMSLGK 229
+ L +
Sbjct: 12296 SDPLSE 12301
Score = 32.3 bits (72), Expect = 0.35
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ TPTS+ TI Y +TA +P+G+ V + P PP V +S
Sbjct: 13931 ITSTPTSSMLTIKYATRKDAGEYT--ITATNPFGTKVEHVKVTVLDV--PGPPGPVEISN 13986
Query: 140 LAERQLQVQWEPP 152
++ + + W PP
Sbjct: 13987 VSAEKATLTWTPP 13999
Score = 32.0 bits (71), Expect = 0.45
Identities = 32/148 (21%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 76 SWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII------KP 129
+W + T T+ IT +L + Y + A + +G S+ P ++ +I +P
Sbjct: 17954 TWHMVSATVARTTIKIT--KLKTGTEYQFRIFAENRYGKSA---PLDSKAVIVQYPFKEP 18008
Query: 130 DPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATS 187
PP ++ +++ Q+ VQW P + +I + Y + K + + + ++ PI+ T
Sbjct: 18009 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKI--IGYHLEQKEKNSILWVKLNKTPIQDTK 18066
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGELS 215
F + Y +V+A+++ G+ S
Sbjct: 18067 FKTTGLDEGLEYEFKVSAENIVGIGKPS 18094
Score = 32.0 bits (71), Expect = 0.45
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 85 TSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRLSPL 140
T+T T+T L A Y + A + G S +S + KP P + + +
Sbjct: 23888 TTTMYTVTG--LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSI 23945
Query: 141 AERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGP--IEATSFILRAVRPRAR 198
++ + +QWE P EI L YW+ Y++ G + + + I+ F + +
Sbjct: 23946 SKDSVTLQWEKPECDGGKEI--LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATE 24003
Query: 199 YYVQVAAQDLT 209
Y +V A++ T
Sbjct: 24004 YEFRVFAENET 24014
Score = 31.2 bits (69), Expect = 0.77
Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 14/187 (7%)
Query: 43 AVDCSWTLPPAPNSTSPVS-FIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAP 101
++ SW PP + +P+S ++ R A W + ++ T ++ T +L
Sbjct: 23351 SITISWE-PPELDGGAPLSGYVVEQR---DAHRPGWLPVSESVTRSTFKFT--RLTEGNE 23404
Query: 102 YVLNVTAVHPWGSSSSFVPFITE---HIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFP 158
YV V A + +G S + E I P PPE +++ ++ + + W PP
Sbjct: 23405 YVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGS 23464
Query: 159 EIFSLKYWIRYKRQGAARFHRVG--PIEATSFILRAVRPRARYYVQVAAQDLTDYGELSD 216
++ Y + K A R+ RV P+ T + + Y +V A + G+ S
Sbjct: 23465 QVTG--YIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSR 23522
Query: 217 WSLPATA 223
S P A
Sbjct: 23523 PSKPIVA 23529
Score = 30.8 bits (68), Expect = 1.0
Identities = 43/202 (21%), Positives = 78/202 (38%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV-SFIATYRLGMAARGHSWPCLQ 81
GPP + + V + +WT PP + SP+ S+I R W +
Sbjct: 13977 GPPGPVEISNVSAEKATL------TWT-PPLEDGGSPIKSYILEKR---ETSRLLWTVVS 14026
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSS---SFVPFITEHIIKPDPPEGVRLS 138
+ SC +L Y+ V+AV+ +G S + + P PPE +S
Sbjct: 14027 ED--IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVS 14084
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEATSFILRAVRPR 196
+ + V W+ P EI Y + + + + R+ R P+ + ++
Sbjct: 14085 NVTKNTATVSWKRPVDDGGSEITG--YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEG 14142
Query: 197 ARYYVQVAAQDLTDYGELSDWS 218
+ Y +V+A++ G S+ S
Sbjct: 14143 STYEFRVSAENRAGIGPPSEAS 14164
Score = 30.8 bits (68), Expect = 1.0
Identities = 37/202 (18%), Positives = 80/202 (39%), Gaps = 20/202 (9%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP +T+ V ++ SW +P ++ R A +W +
Sbjct: 19782 GPPTNITVQDVTKESAVL------SWDVPENDGGAPVKNYHIEKR---EASKKAWVSVTN 19832
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLS 138
S +T++Q A Y V+ + +G +P T+ +K P PPE + ++
Sbjct: 19833 NCNRLSYKVTNLQ--EGAIYYFRVSGENEFGVG---IPAETKEGVKITEKPSPPEKLGVT 19887
Query: 139 PLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRAR 198
+++ + + W P I + Y + +G + + ++T ++ +R +
Sbjct: 19888 SISKDSVSLTWLKPEHDGGSRI--VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSE 19945
Query: 199 YYVQVAAQDLTDYGELSDWSLP 220
Y+ +V A++ + + LP
Sbjct: 19946 YFFRVFAENQAGLSDPRELLLP 19967
Score = 30.4 bits (67), Expect = 1.3
Identities = 14/47 (29%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 106 VTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPP 152
+TA + GS S+ + + + KP PP V+++ + + + WEPP
Sbjct: 12871 ITAENSSGSKSATIKL--KVLDKPGPPASVKINKMYSDRAMLSWEPP 12915
Score = 30.0 bits (66), Expect = 1.7
Identities = 28/134 (20%), Positives = 49/134 (36%), Gaps = 15/134 (11%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
GPP L + + + R SW +P ++ R G +W +
Sbjct: 9416 GPPKDLKVSDITRGSCRL------SWKMPDDDGGDRIKGYVIEKR---TIDGKAWTKVNP 9466
Query: 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPF----ITEHIIKPDPPEGVRLS 138
ST+ + D L S Y V A + +G + I PDPP +++
Sbjct: 9467 DCGSTTFVVPD--LLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIG 9524
Query: 139 PLAERQLQVQWEPP 152
+ + + + W+PP
Sbjct: 9525 LITKNTVHLSWKPP 9538
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 77 WPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFV--PFITEH-IIKPDPPE 133
W + + SC +T +L Y + AV+ +G P + ++ + PD P+
Sbjct: 16187 WTVVDANVQTLSCKVT--KLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK 16244
Query: 134 GVRLSPLAERQLQVQWEPPGS 154
++ + + + V WE P S
Sbjct: 16245 APEVTTVTKDSMIVVWERPAS 16265
Score = 28.9 bits (63), Expect = 3.8
Identities = 16/68 (23%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 86 STSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHII-KPDPPEGVRLSPLAERQ 144
S+ ++T + YV+ T ++ SFV + T +++ KP P +++ ++ +
Sbjct: 11761 SSKFSLTKAKRSDGGKYVVTAT-----NTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11815
Query: 145 LQVQWEPP 152
V W+PP
Sbjct: 11816 CTVCWDPP 11823
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
+ + T TS +I + + Y L V+ + S VP + +P PP +R+
Sbjct: 18946 VSSSKTVTSLSIKEASKEDVGTYELCVSN----SAGSITVPITIIVLDRPGPPGPIRIDE 19001
Query: 140 LAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVG-PIEATSFILRAVRPRAR 198
++ + + W PP +I + Y + K + +H V + TS + + +
Sbjct: 19002 VSCDSITISWNPPEYDGGCQISN--YIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSE 19059
Query: 199 YYVQVAAQDLTDYGELS 215
Y +V A++ YG+ S
Sbjct: 19060 YQFRVCAEN--RYGKSS 19074
Score = 28.1 bits (61), Expect = 6.5
Identities = 47/207 (22%), Positives = 74/207 (35%), Gaps = 27/207 (13%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAAR-GHSWPCLQ 81
GPP AL + V R VD W PP + P+ Y + R G W
Sbjct: 7688 GPPYALAVVDVTKRH------VDLKWE-PPKNDGGRPIQ---RYVIEKKERLGTRWVKAG 7737
Query: 82 QTPTSTSCTITDVQLFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPPEGVRL 137
+T C + V A + G S + + I + P PP + +
Sbjct: 7738 KT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHV 7796
Query: 138 SPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVG--PIEATSF-ILR 191
+ + + + W+PP G P + Y + G ++ RV PI+ F +
Sbjct: 7797 TDAGRKHIAIAWKPPEKNGGSPI-----IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEE 7851
Query: 192 AVRPRARYYVQVAAQDLTDYGELSDWS 218
V P Y ++V A + E S+ S
Sbjct: 7852 GVVPDKEYVLRVRAVNAIGVSEPSEIS 7878
Score = 28.1 bits (61), Expect = 6.5
Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Query: 129 PDPPEGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGPIE- 184
P P + ++ S + + ++ WEPP G P L Y + + G + V E
Sbjct: 7983 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPI-----LHYVLERREAGRRTYIPVMSGEN 8037
Query: 185 ATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
S+ ++ + P Y+ +V A + GE + P A
Sbjct: 8038 KLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8076
Score = 28.1 bits (61), Expect = 6.5
Identities = 25/121 (20%), Positives = 47/121 (38%), Gaps = 9/121 (7%)
Query: 89 CTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQ 144
CT L Y V A + +G P T +K P PP+ + + + +
Sbjct: 14427 CTYKVTGLSEGCEYFFRVMAENEYGIGE---PTETTEPVKASEAPSPPDSLNIMDITKST 14483
Query: 145 LQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVA 204
+ + W P +I Y I +R+G+ ++ + ++ ++R + Y QV
Sbjct: 14484 VSLAWPKPKHDGGSKITG--YVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14541
Query: 205 A 205
A
Sbjct: 14542 A 14542
Score = 28.1 bits (61), Expect = 6.5
Identities = 28/133 (21%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 95 QLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIK----PDPPEGVRLSPLAERQLQVQWE 150
QL Y V A + +G +P T +K P PP + L + + + WE
Sbjct: 15517 QLQEGCSYYFRVLAENEYGIG---LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWE 15573
Query: 151 PPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTD 210
P I L Y + + +G+ ++ ++ T + + Y +V+AQ+
Sbjct: 15574 KPEHDGGSRI--LGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKG 15631
Query: 211 YGELSDWSLPATA 223
+ S+P A
Sbjct: 15632 ISDPRQLSVPVIA 15644
Score = 27.7 bits (60), Expect = 8.5
Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 13/116 (11%)
Query: 43 AVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPY 102
+V +W PP + SP++ + ++ + +W + T T+ D L Y
Sbjct: 7006 SVHLTWE-PPDDDGGSPLTGYVVEKREVSRK--TWTKVMDFVTDLEFTVPD--LVQGKEY 7060
Query: 103 VLNVTAVHPWGSSSSFVPFITEHI------IKPDPPEGVRLSPLAERQLQVQWEPP 152
+ V A + G ++ E + PDPPE V+ + + W+PP
Sbjct: 7061 LFKVCARNKCGPGEP--AYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7114
Score = 27.7 bits (60), Expect = 8.5
Identities = 50/219 (22%), Positives = 79/219 (36%), Gaps = 35/219 (15%)
Query: 23 GPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHS-WPCLQ 81
GPP P+V R + SWT PP N SP++ Y L G W +
Sbjct: 9103 GPPGK---PKVLARTKGSMLV---SWT-PPLDNGGSPIT---GYWLEKREEGSPYWSRVS 9152
Query: 82 QTPTSTSCTITDVQ-----LFSMAPYVLNVTAVHPWG----SSSSFVPFITEHIIKPDPP 132
+ P T + V+ L Y A++ G S S + I P PP
Sbjct: 9153 RAPI-TKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPP 9211
Query: 133 EGVRLSPLAERQLQVQWEPP---GSWPFPEIFSLKYWIRYKRQGAARFHRVGP----IEA 185
+ + + + W+PP G P Y + + +G + RV I
Sbjct: 9212 SCPEVKDKTKSSISLGWKPPAKDGGSPIK-----GYIVEMQEEGTTDWKRVNEPDKLITT 9266
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWS--LPAT 222
++ ++ +Y +V A + E SD + +PAT
Sbjct: 9267 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 9305
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 128 KPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRV--GPIEA 185
+PDPPE ++S + ++ V W PP I Y++ K + + R+ V I
Sbjct: 11901 RPDPPEVTKVS---KEEMTVVWNPPEYDGGKSITG--YFLEKKEKHSTRWVPVNKSAIPE 11955
Query: 186 TSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
++ + P Y +V A++ GE S S P A
Sbjct: 11956 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 11993
>gi|4503993 growth hormone receptor precursor [Homo sapiens]
Length = 638
Score = 41.6 bits (96), Expect = 6e-04
Identities = 54/244 (22%), Positives = 92/244 (37%), Gaps = 34/244 (13%)
Query: 4 QLLLALVLWASCPPCSGRKGPPAALTL---------PRVQCRASRYPI----------AV 44
QLLL L L S SG + A L+ P ++ +S+ P
Sbjct: 5 QLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETF 64
Query: 45 DCSWT--LPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTS-TSCTITDVQLFSMAP 101
C WT + + P+ T R C SC P
Sbjct: 65 SCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIP 124
Query: 102 YVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPL------AERQLQVQWEPPGSW 155
Y + +T+ G + F + I++PDPP + + L +QV+WE P +
Sbjct: 125 YCIKLTSN---GGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNA 181
Query: 156 PFPEIFS-LKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLT--DYG 212
+ + L+Y ++YK ++ + PI TS + +++ Y V+V ++ +YG
Sbjct: 182 DIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYG 241
Query: 213 ELSD 216
E S+
Sbjct: 242 EFSE 245
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 40.8 bits (94), Expect = 0.001
Identities = 51/206 (24%), Positives = 75/206 (36%), Gaps = 23/206 (11%)
Query: 17 PCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHS 76
PC+ P LT + + V+ WT P + + T G
Sbjct: 324 PCTRPPSAPHYLTAVGMGAK-------VELRWTPPQDSGGREDIVYSVTCEQCWPESGEC 376
Query: 77 WPC-----LQQTP---TSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHI-I 127
PC + P T TS T++D++ Y V A + + F T + I
Sbjct: 377 GPCEASVRYSEPPHGLTRTSVTVSDLE--PHMNYTFTVEARNGVSGLVTSRSFRTASVSI 434
Query: 128 KPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATS 187
P VRL + L V W P P + KY + Y+++G + + V E S
Sbjct: 435 NQTEPPKVRLEGRSTTSLSVSWSIP---PPQQSRVWKYEVTYRKKGDSNSYNVRRTEGFS 491
Query: 188 FILRAVRPRARYYVQVAAQDLTDYGE 213
L + P Y VQV Q LT G+
Sbjct: 492 VTLDDLAPDTTYLVQV--QALTQEGQ 515
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 12/104 (11%)
Query: 102 YVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIF 161
Y++N+ AVH +S V IT I DPP+ + +S + + + V W PP +
Sbjct: 840 YIVNLVAVHGTVTSEPIVGSITTGI---DPPKDITISNVTKDSVMVSWSPP-------VA 889
Query: 162 SLKYW-IRYKRQGAARF-HRVGPIEATSFILRAVRPRARYYVQV 203
S Y+ + Y+ R V P T F + + P Y + +
Sbjct: 890 SFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISL 933
Score = 31.2 bits (69), Expect = 0.77
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 102 YVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIF 161
Y++NV A+ S ++ I D P + + +++ V+W PP + +
Sbjct: 480 YIVNVVALKEQARSPPTSASVSTVI---DGPTQILVRDVSDTVAFVEWIPPRAKV--DFI 534
Query: 162 SLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAA 205
LKY + G F P+ + + ++A+RP +RY V V+A
Sbjct: 535 LLKYGLVGGEGGRTTFRLQPPL--SQYSVQALRPGSRYEVSVSA 576
Score = 30.0 bits (66), Expect = 1.7
Identities = 33/130 (25%), Positives = 49/130 (37%), Gaps = 16/130 (12%)
Query: 80 LQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSP 139
LQQ +T +L Y ++V AV S + H+ P+G++
Sbjct: 369 LQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHL---STPQGLQFKT 425
Query: 140 LAERQLQVQWEPPGSWPFPEIFSLKYW----IRYKRQGAARFHRVGPIEATSFILRAVRP 195
+ E ++VQWEP FS W I +G P + TSF ++P
Sbjct: 426 ITETTVEVQWEPFS-------FSFDGWEISFIPKNNEGGVIAQ--VPSDVTSFNQTGLKP 476
Query: 196 RARYYVQVAA 205
Y V V A
Sbjct: 477 GEEYIVNVVA 486
Score = 28.5 bits (62), Expect = 5.0
Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 130 DPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFI 189
DPP + S + + + W+PP + EI + Y + YK +R + E T
Sbjct: 1042 DPPANLTASEVTRQSALISWQPPRA----EIEN--YVLTYKSTDGSRKELIVDAEDTWIR 1095
Query: 190 LRAVRPRARYYVQV-AAQDLT 209
L + Y V + AAQD T
Sbjct: 1096 LEGLLENTDYTVLLQAAQDTT 1116
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 39.7 bits (91), Expect = 0.002
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 9/135 (6%)
Query: 87 TSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVP-----FITEHIIKPDPPEGVRLSPLA 141
T C ++ L++ PY ++ A++ S S F P IT + P +
Sbjct: 387 TECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSAT 446
Query: 142 ERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFH-RVGPIEATSFILRAVRPRARYY 200
R + + W P P L Y IRY + F+ + + + + +RP Y
Sbjct: 447 MRSITLSWPQPEQ---PNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYV 503
Query: 201 VQVAAQDLTDYGELS 215
VQV A+ + YG+ S
Sbjct: 504 VQVRARTVAGYGKFS 518
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 37.4 bits (85), Expect = 0.011
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 13/127 (10%)
Query: 96 LFSMAPYVLNVTAVHPWGSSSSFVPF-----ITEHIIKPDPPEGVRLSPLAERQLQVQWE 150
L + Y V AV+ S P IT + P +RL + L + W
Sbjct: 415 LLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWA 474
Query: 151 PPGSWPFPEIFSLKYWIRY--KRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDL 208
PP P L Y ++Y K +G A + S L +RP ARY VQV A+ +
Sbjct: 475 PPER---PNGVILDYEMKYFEKSEGIAS---TVTSQMNSVQLDGLRPDARYVVQVRARTV 528
Query: 209 TDYGELS 215
YG+ S
Sbjct: 529 AGYGQYS 535
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 37.0 bits (84), Expect = 0.014
Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 8/149 (5%)
Query: 57 TSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSS 116
T P S + YR+ + Q+ P S + L Y V AV S
Sbjct: 928 TPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK 987
Query: 117 SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAAR 176
P + K D P ++ + + V+W PP + +I + + R+G R
Sbjct: 988 ---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
Query: 177 FHRVGPIEATSFILRAVRPRARYYVQVAA 205
+ VGP + + LR ++P + Y V + A
Sbjct: 1041 QYNVGP-SVSKYPLRNLQPASEYTVSLVA 1068
Score = 35.8 bits (81), Expect = 0.031
Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 14/152 (9%)
Query: 56 STSPVSFIATYRLGMAARGHSWPCLQQT--PTSTSCTITDVQLFSMAPYVLNVTAVHPWG 113
S+SPV+ YR+ + P +T P T TI +Q YV++V A +P G
Sbjct: 1565 SSSPVT---GYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ--PTVEYVVSVYAQNPSG 1619
Query: 114 SSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQG 173
S P + + D P+G+ + + +++ WE P ++ + G
Sbjct: 1620 ESQ---PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDG 1672
Query: 174 AARFHRVGPIEATSFILRAVRPRARYYVQVAA 205
E + L+ +RP + Y V V A
Sbjct: 1673 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
Score = 35.4 bits (80), Expect = 0.041
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 7/152 (4%)
Query: 58 SPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSS-S 116
+P + YR+ G + P + T + T T L Y + V AV G S +
Sbjct: 1470 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
Query: 117 SFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKR-QGAA 175
S P + + D P ++++ + + + V+W P S + + K G
Sbjct: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS----PVTGYRVTTTPKNGPGPT 1585
Query: 176 RFHRVGPIEATSFILRAVRPRARYYVQVAAQD 207
+ GP + T + ++P Y V V AQ+
Sbjct: 1586 KTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQN 1616
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,550,445
Number of Sequences: 37866
Number of extensions: 503765
Number of successful extensions: 1752
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 78
Number of HSP's that attempted gapping in prelim test: 1361
Number of HSP's gapped (non-prelim): 433
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.