Guide to the Human Genome
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Name: LEPR Sequence: fasta or formatted (1165aa) NCBI GI: 40254464
Description:

leptin receptor isoform 1

Referenced in:

Adipose Tissue
Hypothalamus
Interleukins and Their Receptors

Other entries for this name:
alt prot [896aa] leptin receptor isoform 2
alt prot [958aa] leptin receptor isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             2.7         31           1
 C cysteine            3.3         39           2
 D aspartate           4.5         53           2
 E glutamate           5.7         66           2
 F phenylalanine       4.8         56           2
 G glycine             3.9         46           2
 H histidine           2.6         30           2
 I isoleucine          6.8         79           2
 K lysine              6.7         78           2
 L leucine             8.9        104           3
 M methionine          2.1         24           2
 N asparagine          5.7         66           2
 P proline             5.9         69           2
 Q glutamine           3.6         42           2
 R arginine            2.2         26           1
 S serine             11.0        128           3
 T threonine           6.0         70           2
 V valine              7.4         86           2
 W tryptophan          2.3         27           2
 Y tyrosine            3.9         45           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   leptin receptor isoform 1 
LEPR                  0.770   leptin receptor isoform 3 
LEPR                  0.770   leptin receptor isoform 2 
IL6ST                 0.033   interleukin 6 signal transducer isoform 1 precursor ...
CSF3R                 0.023   colony stimulating factor 3 receptor isoform d precu...
CSF3R                 0.023   colony stimulating factor 3 receptor isoform c precu...
CSF3R                 0.023   colony stimulating factor 3 receptor isoform b precu...
CSF3R                 0.023   colony stimulating factor 3 receptor isoform a precur...
LIFR                  0.021   leukemia inhibitory factor receptor precursor 
LIFR                  0.021   leukemia inhibitory factor receptor precursor [Homo...
IL31RA                0.018   gp130-like monocyte receptor 
OSMR                  0.015   oncostatin M receptor 
IL6ST                 0.015   interleukin 6 signal transducer isoform 2 precursor ...
IL12RB2               0.015   interleukin 12 receptor, beta 2 precursor 
EBI3                  0.014   Epstein-Barr virus induced 3 precursor 
CRLF1                 0.013   cytokine receptor-like factor 1 
PTPRQ                 0.012   protein tyrosine phosphatase, receptor type, Q [Hom...
IL21R                 0.011   interleukin 21 receptor precursor 
IL21R                 0.011   interleukin 21 receptor precursor 
IL21R                 0.011   interleukin 21 receptor precursor 
PRLR                  0.008   prolactin receptor 
IL11RA                0.008   interleukin 11 receptor, alpha isoform 1 precursor ...
IL11RA                0.008   interleukin 11 receptor, alpha isoform 2 precursor [...
IL11RA                0.008   interleukin 11 receptor, alpha isoform 1 precursor [H...
MPL                   0.007   myeloproliferative leukemia virus oncogene precursor ...
IL13RA2               0.007   interleukin 13 receptor, alpha 2 precursor 
IL6R                  0.007   interleukin 6 receptor isoform 1 precursor 
IL6R                  0.007   interleukin 6 receptor isoform 2 precursor 
IL23R                 0.006   interleukin 23 receptor precursor 
CSF2RB                0.006   colony stimulating factor 2 receptor, beta precursor ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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