Guide to the Human Genome
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Name: LEPR Sequence: fasta or formatted (896aa) NCBI GI: 51093379
Description:

leptin receptor isoform 2

Referenced in:

Adipose Tissue
Hypothalamus
Interleukins and Their Receptors

Other entries for this name:
alt prot [1165aa] leptin receptor isoform 1
alt prot [958aa] leptin receptor isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             2.7         24           1
 C cysteine            3.5         31           2
 D aspartate           4.5         40           2
 E glutamate           4.6         41           1
 F phenylalanine       4.5         40           2
 G glycine             4.0         36           2
 H histidine           2.7         24           2
 I isoleucine          7.3         65           2
 K lysine              6.6         59           2
 L leucine             9.2         82           3
 M methionine          2.1         19           1
 N asparagine          5.7         51           2
 P proline             6.1         55           2
 Q glutamine           3.6         32           2
 R arginine            2.6         23           1
 S serine             10.2         91           3
 T threonine           5.2         47           2
 V valine              7.9         71           2
 W tryptophan          2.8         25           2
 Y tyrosine            4.5         40           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   leptin receptor isoform 2 
LEPR                  0.995   leptin receptor isoform 3 
LEPR                  0.995   leptin receptor isoform 1 
IL6ST                 0.042   interleukin 6 signal transducer isoform 1 precursor ...
CSF3R                 0.030   colony stimulating factor 3 receptor isoform d precu...
CSF3R                 0.030   colony stimulating factor 3 receptor isoform c precu...
CSF3R                 0.030   colony stimulating factor 3 receptor isoform b precu...
CSF3R                 0.030   colony stimulating factor 3 receptor isoform a precur...
LIFR                  0.027   leukemia inhibitory factor receptor precursor 
LIFR                  0.027   leukemia inhibitory factor receptor precursor [Homo...
IL31RA                0.023   gp130-like monocyte receptor 
OSMR                  0.020   oncostatin M receptor 
IL6ST                 0.020   interleukin 6 signal transducer isoform 2 precursor ...
IL12RB2               0.019   interleukin 12 receptor, beta 2 precursor 
EBI3                  0.018   Epstein-Barr virus induced 3 precursor 
CRLF1                 0.017   cytokine receptor-like factor 1 
PTPRQ                 0.015   protein tyrosine phosphatase, receptor type, Q [Hom...
IL21R                 0.014   interleukin 21 receptor precursor 
IL21R                 0.014   interleukin 21 receptor precursor 
IL21R                 0.014   interleukin 21 receptor precursor 
PRLR                  0.011   prolactin receptor 
IL11RA                0.010   interleukin 11 receptor, alpha isoform 1 precursor ...
IL11RA                0.010   interleukin 11 receptor, alpha isoform 2 precursor [...
IL11RA                0.010   interleukin 11 receptor, alpha isoform 1 precursor [H...
MPL                   0.009   myeloproliferative leukemia virus oncogene precursor ...
IL13RA2               0.009   interleukin 13 receptor, alpha 2 precursor 
IL6R                  0.009   interleukin 6 receptor isoform 1 precursor 
IL6R                  0.009   interleukin 6 receptor isoform 2 precursor 
IL23R                 0.008   interleukin 23 receptor precursor 
CSF2RB                0.008   colony stimulating factor 2 receptor, beta precursor ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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