Guide to the Human Genome
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Search of human proteins with 145207994

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
         (225 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145207994 hairy and enhancer of split 7 [Homo sapiens]             475   e-134
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]     97   1e-20
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]    96   2e-20
gi|58219048 hairy and enhancer of split 5 [Homo sapiens]               78   5e-15
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]       74   1e-13
gi|5031763 hairy and enhancer of split 1 [Homo sapiens]                73   2e-13
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i...    70   2e-12
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i...    69   2e-12
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ...    66   3e-11
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho...    62   5e-10
gi|66912172 hairy and enhancer of split 3 [Homo sapiens]               60   1e-09
gi|18959210 WIRE protein [Homo sapiens]                                60   2e-09
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]    56   2e-08
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]     55   4e-08
gi|56549694 enabled homolog isoform a [Homo sapiens]                   55   5e-08
gi|39930375 enabled homolog isoform b [Homo sapiens]                   55   5e-08
gi|22027541 programmed cell death 7 [Homo sapiens]                     55   6e-08
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 53   2e-07
gi|58530845 zyxin [Homo sapiens]                                       52   3e-07
gi|4508047 zyxin [Homo sapiens]                                        52   3e-07
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    52   4e-07
gi|33356148 formin-like 1 [Homo sapiens]                               52   4e-07
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    52   5e-07
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    52   5e-07
gi|153792074 proline rich 12 [Homo sapiens]                            52   5e-07
gi|11386183 WAS protein family, member 2 [Homo sapiens]                51   7e-07
gi|160707881 formin 2 [Homo sapiens]                                   51   9e-07
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    51   9e-07
gi|32483397 dopamine receptor D4 [Homo sapiens]                        50   1e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     50   1e-06

>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
          Length = 225

 Score =  475 bits (1222), Expect = e-134
 Identities = 225/225 (100%), Positives = 225/225 (100%)

Query: 1   MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILE 60
           MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILE
Sbjct: 1   MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILE 60

Query: 61  FAVGYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFS 120
           FAVGYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFS
Sbjct: 61  FAVGYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFS 120

Query: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180
           ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC
Sbjct: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180

Query: 181 SPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
           SPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP
Sbjct: 181 SPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225


>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
          Length = 221

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 84/226 (37%), Positives = 108/226 (47%), Gaps = 40/226 (17%)

Query: 4   RDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV 63
           R  AE+R   K  KP++EKRRR RIN SL +L+ L+L+  R ++ R+ KLEKA+ILE  V
Sbjct: 29  RSAAEHR---KSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTV 85

Query: 64  GYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAF--AHDASPA-ARAQLFS 120
            +LR   RV+      + +    A+   Y +GF ECL  +  F    +  PA  R++L  
Sbjct: 86  RHLRSLRRVQ----VTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLG 141

Query: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180
            L   LR   P  +P          SL PAAPA  PA    P V+ G P       PSL 
Sbjct: 142 HLAACLRQLGPSRRPA---------SLSPAAPAEAPA----PEVYAGRP-----LLPSL- 182

Query: 181 SPRAGDSGAPAPLTGLLPP--PPPPHRQDGAPKAPLPPPPAFWRPW 224
                  G P PL  L PP  P        AP+A    P   WRPW
Sbjct: 183 -------GGPFPL--LAPPLLPGLTRALPAAPRAGPQGPGGPWRPW 219


>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
          Length = 247

 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 80/217 (36%), Positives = 104/217 (47%), Gaps = 37/217 (17%)

Query: 13  PKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRV 72
           P+  KP++EKRRR RIN SL +L+ L+L+  R ++ R+ KLEKA+ILE  V +LR   RV
Sbjct: 61  PQSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRV 120

Query: 73  EPPGVPRSPVQDAEALASCYLSGFRECLLRLAAF--AHDASPA-ARAQLFSALHGYLRPK 129
           +      + +    A+   Y +GF ECL  +  F    +  PA  R++L   L   LR  
Sbjct: 121 Q----VTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 176

Query: 130 PPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGA 189
            P  +P          SL PAAPA  PA    P V+ G P       PSL        G 
Sbjct: 177 GPSRRPA---------SLSPAAPAEAPA----PEVYAGRP-----LLPSL--------GG 210

Query: 190 PAPLTGLLPP--PPPPHRQDGAPKAPLPPPPAFWRPW 224
           P PL  L PP  P        AP+A    P   WRPW
Sbjct: 211 PFPL--LAPPLLPGLTRALPAAPRAGPQGPGGPWRPW 245


>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
          Length = 166

 Score = 78.2 bits (191), Expect = 5e-15
 Identities = 58/151 (38%), Positives = 75/151 (49%), Gaps = 15/151 (9%)

Query: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVE 73
           ++ KP+VEK RRDRIN S+E+L+ LLLE+   ++  N KLEKA+ILE AV YL+      
Sbjct: 18  RLRKPVVEKMRRDRINSSIEQLK-LLLEQEFARHQPNSKLEKADILEMAVSYLKHSKAFV 76

Query: 74  PPGVPRSPVQDAEALASCYLSGFRECLLRLAAF--AHDASPAARAQLFSALHGYLRPKPP 131
               P+S  QD       Y  G+  CL     F   H AS      L+   H    P  P
Sbjct: 77  AAAGPKSLHQD-------YSEGYSWCLQEAVQFLTLHAASDTQMKLLY---HFQRPPAAP 126

Query: 132 RPKPVDPRPP--APRPSLDPAAPALGPALHQ 160
                +P+ P  AP P+L   A A   A HQ
Sbjct: 127 AAPAKEPKAPGAAPPPALSAKATAAAAAAHQ 157


>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
          Length = 173

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 72/227 (31%), Positives = 90/227 (39%), Gaps = 69/227 (30%)

Query: 5   DRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVG 64
           D AE R   K LKPL+EKRRR RIN+SL +L+ L+L     +N    KLEKA++LE  V 
Sbjct: 9   DAAELR---KSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVR 65

Query: 65  YLRERSRVEPPGVPRSPVQDAEAL-ASCYLSGFRECLLRLAAFAHDASPAARAQLFSALH 123
           +L+E        +P S    A  L    Y  G+  C+ RLA                   
Sbjct: 66  FLQE--------LPASSWPTAAPLPCDSYREGYSACVARLARVL---------------- 101

Query: 124 GYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPR 183
                                    PA   L PA+  R   H      R A S +L   R
Sbjct: 102 -------------------------PACRVLEPAVSARLLEHLW----RRAASATLDGGR 132

Query: 184 AGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA------FWRPW 224
           AGDS  P+       P P P        AP+P PP+       WRPW
Sbjct: 133 AGDSSGPSA------PAPAPASAPEPASAPVPSPPSPPCGPGLWRPW 173


>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
          Length = 280

 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 55/186 (29%), Positives = 85/186 (45%), Gaps = 21/186 (11%)

Query: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVE 73
           K  KP++EKRRR RIN SL +L+ L+L+  +  + R+ KLEKA+ILE  V +LR   R +
Sbjct: 36  KSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQ 95

Query: 74  PPGVPRSPVQDAEALASCYLSGFRECLLRLAAF---AHDASPAARAQL-------FSALH 123
                 + +    ++   Y +GF EC+  +  F       +   R +L        + ++
Sbjct: 96  ----MTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQIN 151

Query: 124 GYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPV--HQGHPSPRCAWSPSLCS 181
               P  P P    P PP P P     AP   P     PP+    G  +P    +P    
Sbjct: 152 AMTYPGQPHPALQAPPPPPPGPGGPQHAPFAPP-----PPLVPIPGGAAPPPGGAPCKLG 206

Query: 182 PRAGDS 187
            +AG++
Sbjct: 207 SQAGEA 212



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 15/31 (48%), Positives = 15/31 (48%), Gaps = 2/31 (6%)

Query: 188 GAPAPLTGLLPPPPPPHRQDGAPKAPLPPPP 218
           G P P   L  PPPPP    G   AP  PPP
Sbjct: 157 GQPHP--ALQAPPPPPPGPGGPQHAPFAPPP 185


>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
           isoform a [Homo sapiens]
          Length = 304

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 68/210 (32%), Positives = 86/210 (40%), Gaps = 27/210 (12%)

Query: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVE 73
           K  + ++EKRRRDRIN SL ELR L+      Q   + KLEKAEIL+  V +L+      
Sbjct: 51  KRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQG--SAKLEKAEILQMTVDHLKMLHTAG 108

Query: 74  PPGVPRSPVQDAEALASCYLS-GFRECLLRLAAFAH-----DASPAARAQLFSALHGYLR 127
             G       DA ALA  Y S GFRECL  +A +       DAS   R +L S L+ Y  
Sbjct: 109 GKG-----YFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYAS 163

Query: 128 PKP------------PRPKPVDPRPPAPRPSLDP--AAPALGPALHQRPPVHQGHPSPRC 173
            +             P        P    P L P       G       P HQG      
Sbjct: 164 QREAASGAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAH 223

Query: 174 AWSPSLCSPRAGDSGAPAPLTGLLPPPPPP 203
             +P+L +P +G  G   P+        PP
Sbjct: 224 PEAPALRAPPSGSLGPVLPVVTSASKLSPP 253


>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
           isoform b [Homo sapiens]
          Length = 308

 Score = 69.3 bits (168), Expect = 2e-12
 Identities = 68/212 (32%), Positives = 87/212 (41%), Gaps = 27/212 (12%)

Query: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLR--NPKLEKAEILEFAVGYLRERSR 71
           K  + ++EKRRRDRIN SL ELR L+      Q +   + KLEKAEIL+  V +L+    
Sbjct: 51  KRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHT 110

Query: 72  VEPPGVPRSPVQDAEALASCYLS-GFRECLLRLAAFAH-----DASPAARAQLFSALHGY 125
               G       DA ALA  Y S GFRECL  +A +       DAS   R +L S L+ Y
Sbjct: 111 AGGKG-----YFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNY 165

Query: 126 LRPKP------------PRPKPVDPRPPAPRPSLDP--AAPALGPALHQRPPVHQGHPSP 171
              +             P        P    P L P       G       P HQG    
Sbjct: 166 ASQREAASGAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGS 225

Query: 172 RCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPP 203
               +P+L +P +G  G   P+        PP
Sbjct: 226 AHPEAPALRAPPSGSLGPVLPVVTSASKLSPP 257


>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
           [Homo sapiens]
          Length = 328

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 59/166 (35%), Positives = 78/166 (46%), Gaps = 16/166 (9%)

Query: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVE 73
           K  + ++EKRRRDRIN SL ELR L+   T  +   + KLEKAE+L+  V +L+      
Sbjct: 45  KKRRGIIEKRRRDRINSSLSELRRLV--PTAFEKQGSSKLEKAEVLQMTVDHLKMLHATG 102

Query: 74  PPGVPRSPVQDAEALASCYLS-GFRECLLRLAAF------AHDASPAARAQLFSALHGYL 126
             G       DA ALA  + S GFRECL  +  +          +   R +L S L+ Y 
Sbjct: 103 GTG-----FFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYA 157

Query: 127 RPKPPRPKPVDPRP-PAPRPSLDPAAPALGPALHQRPPVHQGHPSP 171
               P P P  P   PA   S   + P L PAL  +  +    PSP
Sbjct: 158 AEMEPSPTPTGPLAFPAWPWSFFHSCPGL-PALSNQLAILGRVPSP 202


>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
           sapiens]
          Length = 337

 Score = 61.6 bits (148), Expect = 5e-10
 Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 13/115 (11%)

Query: 14  KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVE 73
           K  + ++EKRRRDRIN SL ELR L+   T  +   + KLEKAEIL+  V +L+      
Sbjct: 50  KKRRGIIEKRRRDRINNSLSELRRLV--PTAFEKQGSAKLEKAEILQMTVDHLKMLQATG 107

Query: 74  PPGVPRSPVQDAEALASCYLS-GFRECLLRLAAFAH-----DASPAARAQLFSAL 122
             G       DA ALA  ++S GFRECL  +A +       D+S   R +L S L
Sbjct: 108 GKG-----YFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157


>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
          Length = 186

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 69/220 (31%), Positives = 90/220 (40%), Gaps = 57/220 (25%)

Query: 20  VEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLR--ERSRVEPPGV 77
           +EK+RR RIN SLE+L+ LL E+     +R  KLEKA+ILE +V Y+R  + S      V
Sbjct: 1   MEKKRRARINVSLEQLKSLL-EKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPV 59

Query: 78  PRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVD 137
           PR   Q          SGFR CL  ++            ++ S L   L P+      +D
Sbjct: 60  PRGAEQP---------SGFRSCLPGVSQLLRRGD-----EVGSGLRCPLVPESAAGSTMD 105

Query: 138 PRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLL 197
                    L   APAL              P     W+P   +P AG   +P PL  LL
Sbjct: 106 ------SAGLGQEAPAL------------FRPCTPAVWAP---APAAGGPRSPPPLL-LL 143

Query: 198 PPPPPPHRQDGAPKAPLPPPPA-------------FWRPW 224
           P   P     G+  +  PP PA              WRPW
Sbjct: 144 PESLP-----GSSASVPPPQPASSRCAESPGLGLRVWRPW 178


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 38/98 (38%), Positives = 46/98 (46%), Gaps = 5/98 (5%)

Query: 126 LRPKPP---RPKPVDPRPPAPRPSLDPAAPALGPALHQRPP--VHQGHPSPRCAWSPSLC 180
           L P PP   +P  V   P +P     P  P    +LH++ P  V    P P  + SPSL 
Sbjct: 248 LAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLL 307

Query: 181 SPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPP 218
           S R        P  G  PPPPPP  ++GA  AP PPPP
Sbjct: 308 SNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPP 345



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 14/101 (13%)

Query: 127 RPKPPRPKPVDPRPPAPRPSLDPAAPALGPA---LHQRPPVHQGHPSPRCAWSPSLCSPR 183
           R  PP P PV P P        P+  +L P      Q P V  G  SP    +P L  P+
Sbjct: 221 REGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPEL--PQ 278

Query: 184 AGDS---GAPAPLTGLLPPPPPPHRQDGAPK--APLPPPPA 219
             +S     P P+ GL PPPP       +P   +  PPPPA
Sbjct: 279 RHNSLHRKTPGPVRGLAPPPPT----SASPSLLSNRPPPPA 315



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 43/153 (28%), Positives = 51/153 (33%), Gaps = 21/153 (13%)

Query: 78  PRSPVQDAEALASCYLSGFRECLLRLAAFAHDASP-AARAQLFSAL---HGYLRPKPPRP 133
           PR PV  A           R  L  L      + P  +R    S+    H    P PP P
Sbjct: 123 PRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPP 182

Query: 134 KPVDPRPPAPRPSLDPAAPALGPALHQRP-PVHQGHPSPRCAWSPSLCSPRAGDSGAPAP 192
                 PP P P     APA        P P  + HP               G  G PAP
Sbjct: 183 GRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHP---------------GREGPPAP 227

Query: 193 LTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
              + PPP P + + G     L PPP  +R  P
Sbjct: 228 -PPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPP 259



 Score = 36.6 bits (83), Expect = 0.018
 Identities = 42/142 (29%), Positives = 53/142 (37%), Gaps = 23/142 (16%)

Query: 73  EPPGVPRSPV----QDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRP 128
           +PPGVP  P     + A  L   + S  R+    +   A     +A   L S      RP
Sbjct: 257 QPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSN-----RP 311

Query: 129 KPPRPKPVD--PRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGD 186
            PP   P      PP P P +   A    P     PP ++ H S      PS   P    
Sbjct: 312 PPPARDPPSRGAAPPPPPPVIRNGARDAPPP----PPPYRMHGSE----PPSRGKPPPPP 363

Query: 187 SGAPAPLTGLLPPPPPPHRQDG 208
           S  PA      PPPPPP  ++G
Sbjct: 364 SRTPAGP----PPPPPPPLRNG 381



 Score = 34.3 bits (77), Expect = 0.088
 Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 21/105 (20%)

Query: 127 RPKPPRPKPVDPRPPAPRPSLDPAAPALGPALH--QRPPVHQGHPSPRCAWSPSLCSPRA 184
           R   PRP PV      P+   D +  +L P L   QRP +            P L  P  
Sbjct: 119 RAAAPRP-PVSAASGRPQDDTDSSRASL-PELPRMQRPSL------------PDLSRPNT 164

Query: 185 GDSGAPAPLTGLLPPPPPPHRQDGAPKAPLP----PPPAFWRPWP 225
             S      +   PPPPPP R+  AP  PLP      PA+ R  P
Sbjct: 165 -TSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKP 208



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 13/24 (54%), Positives = 14/24 (58%), Gaps = 7/24 (29%)

Query: 197 LPPPPPPHRQDGAPKAPLPPPPAF 220
           +PPPPPP      P  P PPPP F
Sbjct: 3   IPPPPPP------PPGP-PPPPTF 19



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 17/47 (36%), Positives = 19/47 (40%), Gaps = 10/47 (21%)

Query: 128 PKPPRP------KPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGH 168
           P PP P      +P     P P PS  PA P   P     PP+  GH
Sbjct: 340 PPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPP----PPLRNGH 382


>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
          Length = 222

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 75/250 (30%), Positives = 92/250 (36%), Gaps = 75/250 (30%)

Query: 5   DRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV- 63
           D  E R   K  KPLVEK+RR RIN SL+ELRLLL            KLE AE+LE  V 
Sbjct: 18  DGWETRGDRKARKPLVEKKRRARINESLQELRLLLAG-------AEAKLENAEVLELTVR 70

Query: 64  ---GYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFS 120
              G LR R+R       R  +Q AEA +  + +G+ +C+  +  F              
Sbjct: 71  RVQGVLRGRAR------EREQLQ-AEA-SERFAAGYIQCMHEVHTFVSTCQAIDATVAAE 122

Query: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180
            L+  L   P R                     LG AL   PP   G    R  W     
Sbjct: 123 LLNHLLESMPLREG-------------SSFQDLLGDAL-AGPPRAPG----RSGW----- 159

Query: 181 SPRAGDSGAPAPLTGLLPPPPPPHRQ-----DGAPKAPLPPPPA---------------- 219
            P  G  G+P      +P PP P        + AP+A L   PA                
Sbjct: 160 -PAGGAPGSP------IPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTA 212

Query: 220 -----FWRPW 224
                 WRPW
Sbjct: 213 QIARSVWRPW 222


>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
          Length = 224

 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 75/250 (30%), Positives = 92/250 (36%), Gaps = 73/250 (29%)

Query: 5   DRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV- 63
           D  E R   K  KPLVEK+RR RIN SL+ELRLLL            KLE AE+LE  V 
Sbjct: 18  DGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAE-----VQAKLENAEVLELTVR 72

Query: 64  ---GYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFS 120
              G LR R+R       R  +Q AEA +  + +G+ +C+  +  F              
Sbjct: 73  RVQGVLRGRAR------EREQLQ-AEA-SERFAAGYIQCMHEVHTFVSTCQAIDATVAAE 124

Query: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180
            L+  L   P R                     LG AL   PP   G    R  W     
Sbjct: 125 LLNHLLESMPLREG-------------SSFQDLLGDAL-AGPPRAPG----RSGW----- 161

Query: 181 SPRAGDSGAPAPLTGLLPPPPPPHRQ-----DGAPKAPLPPPPA---------------- 219
            P  G  G+P      +P PP P        + AP+A L   PA                
Sbjct: 162 -PAGGAPGSP------IPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTA 214

Query: 220 -----FWRPW 224
                 WRPW
Sbjct: 215 QIARSVWRPW 224


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 61/228 (26%), Positives = 84/228 (36%), Gaps = 63/228 (27%)

Query: 4   RDRAENRDGPKMLKPLVEKRRRDRINRSLEEL----RLLLLERTRDQNLRNPKLEKAEIL 59
           R+R E  +  + L+      R++R++R  +E     RL  LER R +  R  +LE+ ++ 
Sbjct: 198 RERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL- 256

Query: 60  EFAVGYLRER--SRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQ 117
                + RER  S    P    +P+      +S    G +            + PA    
Sbjct: 257 ----EWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAA----------SQPAETPS 302

Query: 118 LFSALHGYLRPKPPRPKPVDPR------PPAPRPSLDPAAPALGPALHQRPPVHQGHPSP 171
               + G L P PP P P  P       PP P P   P  P+ GP     PP     P P
Sbjct: 303 QQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGP-----PP-----PPP 352

Query: 172 RCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
                             P PL   +PPPPPP         P PP PA
Sbjct: 353 ------------------PPPLPNQVPPPPPP--------PPAPPLPA 374



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 66/224 (29%), Positives = 86/224 (38%), Gaps = 25/224 (11%)

Query: 8   ENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLR 67
           E  +  +M +  +E+ R +R     E L    LER R +  R  +LE+ E LE      R
Sbjct: 159 ERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLER 218

Query: 68  ------------ERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAAR 115
                       ER R+E     R   +  E L    L   RE  +  AA     +PA+ 
Sbjct: 219 QERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAA-----APASV 273

Query: 116 AQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAW 175
               +++ G      P  +      PA  PS       LGP     PP     P P  A 
Sbjct: 274 ETPLNSVLGDSSASEPGLQAASQ--PAETPSQQGIV--LGPLAPPPPPPLP--PGPAQA- 326

Query: 176 SPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
           S +L  P       P P TG  PPPPPP   +  P  P PPPPA
Sbjct: 327 SVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPP-PPPPA 369


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 61/228 (26%), Positives = 84/228 (36%), Gaps = 63/228 (27%)

Query: 4   RDRAENRDGPKMLKPLVEKRRRDRINRSLEEL----RLLLLERTRDQNLRNPKLEKAEIL 59
           R+R E  +  + L+      R++R++R  +E     RL  LER R +  R  +LE+ ++ 
Sbjct: 198 RERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL- 256

Query: 60  EFAVGYLRER--SRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQ 117
                + RER  S    P    +P+      +S    G +            + PA    
Sbjct: 257 ----EWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAA----------SQPAETPS 302

Query: 118 LFSALHGYLRPKPPRPKPVDPR------PPAPRPSLDPAAPALGPALHQRPPVHQGHPSP 171
               + G L P PP P P  P       PP P P   P  P+ GP     PP     P P
Sbjct: 303 QQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGP-----PP-----PPP 352

Query: 172 RCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
                             P PL   +PPPPPP         P PP PA
Sbjct: 353 ------------------PPPLPNQVPPPPPP--------PPAPPLPA 374



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 66/224 (29%), Positives = 86/224 (38%), Gaps = 25/224 (11%)

Query: 8   ENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLR 67
           E  +  +M +  +E+ R +R     E L    LER R +  R  +LE+ E LE      R
Sbjct: 159 ERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLER 218

Query: 68  ------------ERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAAR 115
                       ER R+E     R   +  E L    L   RE  +  AA     +PA+ 
Sbjct: 219 QERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAA-----APASV 273

Query: 116 AQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAW 175
               +++ G      P  +      PA  PS       LGP     PP     P P  A 
Sbjct: 274 ETPLNSVLGDSSASEPGLQAASQ--PAETPSQQGIV--LGPLAPPPPPPLP--PGPAQA- 326

Query: 176 SPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
           S +L  P       P P TG  PPPPPP   +  P  P PPPPA
Sbjct: 327 SVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPP-PPPPA 369


>gi|22027541 programmed cell death 7 [Homo sapiens]
          Length = 485

 Score = 54.7 bits (130), Expect = 6e-08
 Identities = 45/117 (38%), Positives = 50/117 (42%), Gaps = 22/117 (18%)

Query: 124 GYLRPKPPRPKPVDPRP----PAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSL 179
           G  RP PP P+P  P P    P P PS     PA  P L QRP    G  +P     P  
Sbjct: 8   GQGRPGPPPPQPPPPAPFGCPPPPLPS-----PAFPPPLPQRPGPFPGASAPFLQ-PPLA 61

Query: 180 CSPRA--------GDSGAPAPLTGL-LPPPPP---PHRQDGAPKAPLPPPPAFWRPW 224
             PRA        G +GA  P+    LPPPPP   P     A + P PPPP    PW
Sbjct: 62  LQPRASAEASRGGGGAGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPW 118



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 19/42 (45%), Positives = 19/42 (45%), Gaps = 8/42 (19%)

Query: 188 GAPAPLTGLLPPPPPPHRQDGAPKAPLP----PPPAFWRPWP 225
           G P P     PP PPP    G P  PLP    PPP   RP P
Sbjct: 10  GRPGPP----PPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGP 47



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 17/50 (34%), Positives = 21/50 (42%)

Query: 112 PAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQR 161
           P  + + F       RP+PP P P  P  P    +  P A  LG A  QR
Sbjct: 91  PPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQR 140


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 40/112 (35%), Positives = 43/112 (38%), Gaps = 11/112 (9%)

Query: 112 PAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSP 171
           P     L   L   L P PP  +P  P PP P P L P  P  GP     PP   G P P
Sbjct: 444 PPGMPGLRGPLPRLLPPGPPPGRPPGP-PPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPP 502

Query: 172 RCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRP 223
           R    P +  P       PAP  GL PP P P+     P     PP    RP
Sbjct: 503 R----PGMMRPPLVPPLGPAP-PGLFPPAPLPN-----PGVLSAPPNLIQRP 544



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 35/99 (35%), Positives = 37/99 (37%), Gaps = 5/99 (5%)

Query: 128 PKPPRPKPVDP-RPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGD 186
           P P  P P  P RPP P   L P  P   P    RPP   G   P     P    P    
Sbjct: 410 PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPF-LRPPGMPGLRGPLPRLLPPGPPPGRPP 468

Query: 187 SGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
              P P  GL P PPP   +   P+ P P PP    P P
Sbjct: 469 GPPPGPPPGLPPGPPP---RGPPPRLPPPAPPGIPPPRP 504



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 34/96 (35%), Positives = 35/96 (36%), Gaps = 6/96 (6%)

Query: 130 PPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGA 189
           PP+  P       P P   P  P   P L    P     P P     P L  P  G  G 
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPP--GMPGL 450

Query: 190 PAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
             PL  LLPP PPP    G P  P P PP    P P
Sbjct: 451 RGPLPRLLPPGPPP----GRPPGPPPGPPPGLPPGP 482


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 39/110 (35%), Positives = 49/110 (44%), Gaps = 24/110 (21%)

Query: 110 ASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHP 169
           A  A RAQ+     G + P PP   P+ P P A     D A  ALG A    PP  +   
Sbjct: 49  APGAQRAQMGRV--GEIPPPPPEDFPLPPPPLAGDG--DDAEGALGGAFPPPPPPIE--- 101

Query: 170 SPRCAWSPSLCSPRAGDSGAPAPLTG-LLPPPPPPHRQDGAPKAPLPPPP 218
                           +S  PAPL   + P PPPP  ++G P+AP+PPPP
Sbjct: 102 ----------------ESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPP 135



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 27/85 (31%), Positives = 34/85 (40%), Gaps = 20/85 (23%)

Query: 141 PAPRPSLDPAAPAL-------GPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPL 193
           P+P  S+  +APA        GP +  +P V+   P        S   P  G   A    
Sbjct: 6   PSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGD------SEPPPAPGAQRAQMGR 59

Query: 194 TGLLPPPPPPHRQDGAPKAPLPPPP 218
            G +PPPPP          PLPPPP
Sbjct: 60  VGEIPPPPP-------EDFPLPPPP 77



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 27/108 (25%), Positives = 36/108 (33%), Gaps = 4/108 (3%)

Query: 110 ASPAARAQLFSALHGYLRPKPP--RPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQG 167
           A+P +         G   P PP   P    P P  P P+       + P    +P V   
Sbjct: 178 ATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLH 237

Query: 168 HPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPP--PPHRQDGAPKAP 213
             S     S +   PR   + +PAP     P  P   P     +P AP
Sbjct: 238 VQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAP 285


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 39/110 (35%), Positives = 49/110 (44%), Gaps = 24/110 (21%)

Query: 110 ASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHP 169
           A  A RAQ+     G + P PP   P+ P P A     D A  ALG A    PP  +   
Sbjct: 49  APGAQRAQMGRV--GEIPPPPPEDFPLPPPPLAGDG--DDAEGALGGAFPPPPPPIE--- 101

Query: 170 SPRCAWSPSLCSPRAGDSGAPAPLTG-LLPPPPPPHRQDGAPKAPLPPPP 218
                           +S  PAPL   + P PPPP  ++G P+AP+PPPP
Sbjct: 102 ----------------ESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPP 135



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 27/85 (31%), Positives = 34/85 (40%), Gaps = 20/85 (23%)

Query: 141 PAPRPSLDPAAPAL-------GPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPL 193
           P+P  S+  +APA        GP +  +P V+   P        S   P  G   A    
Sbjct: 6   PSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGD------SEPPPAPGAQRAQMGR 59

Query: 194 TGLLPPPPPPHRQDGAPKAPLPPPP 218
            G +PPPPP          PLPPPP
Sbjct: 60  VGEIPPPPP-------EDFPLPPPP 77



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 27/108 (25%), Positives = 36/108 (33%), Gaps = 4/108 (3%)

Query: 110 ASPAARAQLFSALHGYLRPKPP--RPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQG 167
           A+P +         G   P PP   P    P P  P P+       + P    +P V   
Sbjct: 178 ATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLH 237

Query: 168 HPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPP--PPHRQDGAPKAP 213
             S     S +   PR   + +PAP     P  P   P     +P AP
Sbjct: 238 VQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAP 285


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 34/94 (36%), Positives = 37/94 (39%), Gaps = 8/94 (8%)

Query: 128 PKPPRPKPVDPRPPAPRP--SLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAG 185
           P PP P    P PP P P  S  P  PA G      PP      +P  A  P    P   
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSR----APTAAPPPP--PPSRP 330

Query: 186 DSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
               P P    + PPPPP     AP  P PPPP+
Sbjct: 331 SVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPS 364



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 42/108 (38%), Positives = 45/108 (41%), Gaps = 19/108 (17%)

Query: 128 PKPPRPKPVD---PRPPA-------PRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSP 177
           P PP P P +   P PPA       P PS  P A A  P    RP V    P P   + P
Sbjct: 287 PPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA-APPPPPPSRPSVAVPPPPPNRMYPP 345

Query: 178 SLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
               P A  S AP+      PPPPPP      P AP PPPP    P P
Sbjct: 346 P---PPALPSSAPSG-----PPPPPPSVLGVGPVAPPPPPPPPPPPGP 385



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 20/49 (40%), Positives = 20/49 (40%), Gaps = 7/49 (14%)

Query: 182 PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP-------LPPPPAFWRP 223
           P  G    P P      PPPPP R  GAP  P        PPPP   RP
Sbjct: 282 PSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 25/92 (27%), Positives = 29/92 (31%), Gaps = 35/92 (38%)

Query: 130 PPRPKPVDPRPPAPRPSLDPAAP--------ALGPALHQRPPVHQGHPSPRCAWSPSLCS 181
           PP P  + P PP   PS  P+ P         +GP     PP                  
Sbjct: 336 PPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP------------------ 377

Query: 182 PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP 213
                   P P  G  PPPPP    DG  + P
Sbjct: 378 -------PPPPPPG--PPPPPGLPSDGDHQVP 400


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 33/81 (40%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 142 APRPSLDPAAPALGPALHQRPPVHQGHPSPRCA--WSPSLCSPRAGDSGAPA--PLTGLL 197
           +P P L PAA     A    PP   G PSP+ A   +P    P  G    P   PL G L
Sbjct: 525 SPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDL 584

Query: 198 PPPPPPHRQDGAPKAPLPPPP 218
           PPPPPP         P+PPPP
Sbjct: 585 PPPPPPPPPPPGTDGPVPPPP 605



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 39/110 (35%), Positives = 41/110 (37%), Gaps = 28/110 (25%)

Query: 109 DASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGH 168
           D +PAA     +A      P PP P P  P P    PS  P AP L            G 
Sbjct: 529 DLAPAAEPAPGAA------PPPPPPLPGLPSPQEAPPSAPPQAPPL-----------PGS 571

Query: 169 PSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPP 218
           P P  A       P  GD   P P     PPPPPP      P  P PPPP
Sbjct: 572 PEPPPA------PPLPGDLPPPPP-----PPPPPPGTDGPVPPPPPPPPP 610



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 28/98 (28%), Positives = 36/98 (36%), Gaps = 12/98 (12%)

Query: 139 RPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSP-----------SLCSPRAGDS 187
           RPP P  +  PAAP    AL  +    +     R    P           ++ +P  GD+
Sbjct: 458 RPPEPEKA-PPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDA 516

Query: 188 GAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
             P   TG   P   P  +     AP PPPP    P P
Sbjct: 517 PTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSP 554



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 17/106 (16%)

Query: 129 KPPRPKPVDPRPPAPRPSLDPAAPAL------------GPALH-QRPPVHQGHPSPRCAW 175
           +PP P+   P  P    +L+     L            G A+  +  PV    PS   A 
Sbjct: 458 RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAP 517

Query: 176 SPSLCSPRAGDSGAPA--PLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
           +P + +       APA  P  G  PPPPPP    G P     PP A
Sbjct: 518 TPGVPTGSPSPDLAPAAEPAPGAAPPPPPP--LPGLPSPQEAPPSA 561



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 15/48 (31%), Positives = 19/48 (39%)

Query: 128 PKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAW 175
           P PP P P  P P  P  +L      LGP +  + P+      P   W
Sbjct: 600 PVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNW 647


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 40/115 (34%), Positives = 42/115 (36%), Gaps = 8/115 (6%)

Query: 106 FAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALG--PALHQRPP 163
           F   A P      F A  G   P+PP   P  P PP P P      P L   P    RPP
Sbjct: 217 FPGPAGPGGPPPPFPA--GQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP 274

Query: 164 VHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPP 218
                P       P    P     G P P+ G  PPP PP  Q G P  P P PP
Sbjct: 275 PPVLFPGQPFGQPPLGPLP----PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPP 325



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 35/92 (38%), Positives = 37/92 (40%), Gaps = 21/92 (22%)

Query: 135 PVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLT 194
           P+ P PP P P   P     GP     PP  QG P P     P    PR      P PL 
Sbjct: 291 PLPPGPPPPVPGYGPPP---GP-----PPPQQGPPPP-----PGPFPPR-----PPGPLG 332

Query: 195 GLLPPPPPPHRQDGAPKAPLPPP---PAFWRP 223
             L   PPPH     P AP P P   PAF+ P
Sbjct: 333 PPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP 364



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 33/101 (32%), Positives = 37/101 (36%), Gaps = 21/101 (20%)

Query: 128 PKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDS 187
           P PP P+   P PP P P   P    LGP L   PP H   P P                
Sbjct: 307 PGPPPPQQGPPPPPGPFPPRPPGP--LGPPLTLAPPPHLPGPPP---------------- 348

Query: 188 GAPAPLTGLLPPPPPPHRQDGAPKAPL---PPPPAFWRPWP 225
           GAP P   + P   PP    G P +     PP   + RP P
Sbjct: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 40/107 (37%), Positives = 41/107 (38%), Gaps = 19/107 (17%)

Query: 133 PKPVDPR-PPAPRPS-LDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSP-RAGDSGA 189
           P P  P  PP P P+   P  P LGP     PP   G P P     P L  P   GD   
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPP---GPPGPPGPPPPGQVLPPPLAGPPNRGDRPP 274

Query: 190 PA-----------PLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
           P            PL  L P PPPP    G P  P PPPP    P P
Sbjct: 275 PPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPP--PGPPPPQQGPPPP 319



 Score = 36.6 bits (83), Expect = 0.018
 Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 28/104 (26%)

Query: 124 GYLRPKPPRP--KPV----DPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSP 177
           G   P+PP P   P+     P  P P P   P AP + PA    PP + G P+       
Sbjct: 321 GPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP-PPTNSGMPT------- 372

Query: 178 SLCSPRAGDSGAPAPLTGLLPPPP-------PPHRQDGAPKAPL 214
                   DS  P P      PPP       PP R+    + PL
Sbjct: 373 -------SDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 39/104 (37%), Positives = 43/104 (41%), Gaps = 15/104 (14%)

Query: 128 PKPPRPK--PVDPRPP-APRPSLDPAAPAL-------GPALHQRPPVHQGHPSPRCAWSP 177
           P PPRP   P+ PRPP AP P + P  P         GP +   PP     P P   W P
Sbjct: 251 PMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVP--PWPP 308

Query: 178 SLCSPRAGDSGA--PAPLTGLLPPPPPPHR-QDGAPKAPLPPPP 218
               P         P P    +PP PP  R   G P APLPP P
Sbjct: 309 MAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGP 352



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 38/97 (39%), Positives = 42/97 (43%), Gaps = 12/97 (12%)

Query: 126 LRPKPPRPK--PVDPRPP-APRPSLDPAAPA-LGPALHQRPPVHQGHPSPRCAWSPSLCS 181
           + P PP P+  PV P PP AP P   P AP   GP +   PP   G P  R    P +  
Sbjct: 282 MAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPP---GPPMARVPPGPPMAR 338

Query: 182 PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPP 218
              G   AP P     P PP      G P APLPP P
Sbjct: 339 VPPGPPMAPLP-----PGPPMAPLPPGPPMAPLPPGP 370



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 44/120 (36%), Positives = 54/120 (45%), Gaps = 10/120 (8%)

Query: 107 AHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAP-RPSLDPAAPALGPALHQRPPVH 165
           A+ A+PA    L  AL  +L P+ PRP PV P PP P RP + P  P   P +   PP+ 
Sbjct: 222 AYYAAPA----LDPALCVHLVPQLPRP-PVLPVPPMPPRPPMVPMPPR--PPIAPMPPMA 274

Query: 166 QGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
              P  R A  P    PR        P+  + P PP      G P AP+PP P   R  P
Sbjct: 275 PVPPGSRMAPVPP--GPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPP 332



 Score = 31.2 bits (69), Expect = 0.75
 Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 1/56 (1%)

Query: 126 LRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCS 181
           + P PP P P+ P PP P  +  P  P + P   +    H G       W+P + S
Sbjct: 345 MAPLPPGP-PMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINS 399


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 35/96 (36%), Positives = 39/96 (40%), Gaps = 28/96 (29%)

Query: 128  PKPP----RPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPR 183
            P+PP    +P P  P  P P+P   P  P   PAL   PP+    PS             
Sbjct: 1448 PEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPS------------- 1494

Query: 184  AGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
               S  P P    LPPPPPP      P  P PPPPA
Sbjct: 1495 ---SPPPPP----LPPPPPP----AMPSPPPPPPPA 1519



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/108 (31%), Positives = 39/108 (36%), Gaps = 19/108 (17%)

Query: 137  DPRPPAPRPSLDPAAPALGPALH-QRPPVHQGHPSPRCAWSPS--LCSPRAGDSGAPAPL 193
            DP    P+ +  P  P L PA     PP   G PS     +P   L   +   +  PAP 
Sbjct: 1407 DPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466

Query: 194  TGLLPPPPPPHRQDGAPKAPL----------------PPPPAFWRPWP 225
                PPPPPP  Q   P  P                 PPPPA   P P
Sbjct: 1467 PQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPP 1514



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 32/93 (34%), Positives = 39/93 (41%), Gaps = 25/93 (26%)

Query: 128  PKP-PRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGD 186
            P P P+P+P  P PP P+P+L    P + P     PP     P P     P++ SP    
Sbjct: 1463 PAPTPQPQPPPP-PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPP-----PAMPSP---- 1512

Query: 187  SGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
                       PPPPPP     AP A  P  PA
Sbjct: 1513 -----------PPPPPP---AAAPLAAPPEEPA 1531



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 36/100 (36%), Positives = 38/100 (38%), Gaps = 24/100 (24%)

Query: 130  PPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGA 189
            PP   P D   P   P L PAA   GP     PP+            P L  P A  +G 
Sbjct: 1408 PPLAGPKDTSTP-DGPPLAPAAAVPGP-----PPL------------PGL--PSANSNGT 1447

Query: 190  PAP--LTGLLP--PPPPPHRQDGAPKAPLPPPPAFWRPWP 225
            P P  L    P  PPP P  Q   P  P PP PA   P P
Sbjct: 1448 PEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPP 1487



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 27/90 (30%), Positives = 31/90 (34%), Gaps = 9/90 (10%)

Query: 128  PKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDS 187
            P PP   P  P  P       P  P LG   ++ P +    PS   A    L       +
Sbjct: 982  PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL----PSTVNAEPLGLIQSGPHQA 1037

Query: 188  GAPAPLTGLLPPPPPPHRQDGAPKAPLPPP 217
              P P     PPPPPP      PK  L  P
Sbjct: 1038 APPPP-----PPPPPPPAPASEPKGGLTSP 1062



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 44/153 (28%), Positives = 59/153 (38%), Gaps = 35/153 (22%)

Query: 59  LEFAVGYLRERSRVEPPGVPRSPVQDAEALASC---YLSGFRECLLRLAAFAHDASPAAR 115
           LE  +G L+E+ +      P    +  E LA+    Y +G +E    L AF   + P   
Sbjct: 718 LELGLGRLKEKKKG-----PERGGETPEGLATSVVHYGAGAKE----LGAFLQKSPPPPP 768

Query: 116 AQLFSAL---HGYLRPK--PPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPS 170
               S     HG L     P  P  + P PP   PS+   AP+  P+   +  VH   P+
Sbjct: 769 PTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSA-SKVGVHLLEPA 827

Query: 171 PRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPP 203
            R               GAP P     PPPPPP
Sbjct: 828 TR--------------DGAPQPPP---PPPPPP 843



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 33/106 (31%), Positives = 39/106 (36%), Gaps = 14/106 (13%)

Query: 98  ECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPA 157
           + L  + + A   SP+A       L    R   P+P P  P PP P P        L   
Sbjct: 800 QLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP--------LQLE 851

Query: 158 LHQRP-PVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPP 202
            H R   +    PSPR     SL  P     GA   L G L P PP
Sbjct: 852 AHLRSHGLEPAAPSPRLRPEESLDPP-----GAMQELLGALEPLPP 892



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 18/85 (21%)

Query: 128  PKPPRPKPVDPRPP--------APRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSL 179
            P PP P+P  P PP        +P P   P  P   PA+   PP     P P  A +P  
Sbjct: 1473 PPPPPPQPALPSPPPLVAPTPSSPPP--PPLPPPPPPAMPSPPP-----PPPPAA-APLA 1524

Query: 180  CSPRAGDSGAPAPLTGLLPPPPPPH 204
              P   +  AP+P    LP   P H
Sbjct: 1525 APPE--EPAAPSPEDPELPDTRPLH 1547



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 24/77 (31%), Positives = 27/77 (35%), Gaps = 19/77 (24%)

Query: 162  PPVHQGHPSPRCAWSP--SLCSPRAGDSGAPAPLTGLLPPPPP----------------- 202
            P    G P    A+ P    C  RA  +G   P  GL P  PP                 
Sbjct: 974  PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033

Query: 203  PHRQDGAPKAPLPPPPA 219
            PH+    P  P PPPPA
Sbjct: 1034 PHQAAPPPPPPPPPPPA 1050



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 30/96 (31%), Positives = 35/96 (36%), Gaps = 35/96 (36%)

Query: 151 APALGPALHQRPPVHQGHPSPRCAWS--PSLCSPRAGDSGAPAPLTGLLPPPPP------ 202
           A  LG  L + PP     P P  A S  P+         G   PL  +LPPPPP      
Sbjct: 753 AKELGAFLQKSPP-----PPPPTAQSTQPTPHGLLLEAGGPDLPL--VLPPPPPQLLPSV 805

Query: 203 --------------------PHRQDGAPKAPLPPPP 218
                               P  +DGAP+ P PPPP
Sbjct: 806 LSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPP 841



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/96 (31%), Positives = 35/96 (36%), Gaps = 28/96 (29%)

Query: 147 LDPAAPALGPALHQRPPVHQGHPSPRCA----------WSPSLCSPRAGDSGAPA--PLT 194
           L PA   LGPA  Q PP   G P P              + S  +  A +  +P     +
Sbjct: 214 LGPAG--LGPA--QTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFS 269

Query: 195 GLLPPPPPP------------HRQDGAPKAPLPPPP 218
           G  P PPPP            H Q  A   P PPPP
Sbjct: 270 GAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPP 305



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 33/121 (27%), Positives = 37/121 (30%), Gaps = 37/121 (30%)

Query: 122 LHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCS 181
           L G L P PP P      PP      DPA          R P  QG  +PR     S+C 
Sbjct: 883 LLGALEPLPPAPGDTGVGPPNSEGK-DPAGA-------YRSPSPQGTKAPRFVPLTSICF 934

Query: 182 PRA-------------------------GDSGAPA----PLTGLLPPPPPPHRQDGAPKA 212
           P +                         G +G P     P  G  PPP PP      P  
Sbjct: 935 PDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYC 994

Query: 213 P 213
           P
Sbjct: 995 P 995



 Score = 28.5 bits (62), Expect = 4.8
 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 7/47 (14%)

Query: 126  LRPKPPRPKPVDPRPPAP------RPSLDPAAPA-LGPALHQRPPVH 165
            L P PP   P  P PP P       P  +PAAP+   P L    P+H
Sbjct: 1501 LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLH 1547



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 18/75 (24%)

Query: 161  RPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPP----------PPHR--QDG 208
            RPPV    P  R   + +  S  AG S AP P     PP P          PP +  +  
Sbjct: 1669 RPPV----PVRRSGQAKNPVS--AGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETA 1722

Query: 209  APKAPLPPPPAFWRP 223
             P+ P P  P+  RP
Sbjct: 1723 MPEPPAPEKPSLLRP 1737


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 39/102 (38%), Positives = 41/102 (40%), Gaps = 15/102 (14%)

Query: 128 PKPP-RPKPVDPRPPAPRPSLDPAAPALG---PALHQRPPVHQGHPSPRCAWSPSLCSPR 183
           PKP   P P  P PP P   + P  P +G   P     P      P P  A  P    P 
Sbjct: 312 PKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPP 371

Query: 184 AGDSGA--PAPL---TGLLPPPPPPHRQDGAPKAPLPPPPAF 220
           A D     P PL   TG  PPPPPP      P  P PPPP F
Sbjct: 372 AADYPTLPPPPLSQPTGGAPPPPPP------PPPPGPPPPPF 407



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 37/107 (34%), Positives = 40/107 (37%), Gaps = 20/107 (18%)

Query: 128 PKPPRPKPVDPRPPAPRPSL--DPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAG 185
           P  P P P    PP P+P     PA P   P +   PP     P P    SP    P + 
Sbjct: 297 PSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPP----PPPVGFGSPGTPPPPSP 352

Query: 186 DSGAPAPLTGLLPPPPPPHRQD--------------GAPKAPLPPPP 218
            S  P P     PPPPPP   D              GAP  P PPPP
Sbjct: 353 PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP 399



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 32/92 (34%), Positives = 33/92 (35%), Gaps = 9/92 (9%)

Query: 128 PKPPRP----KPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPR 183
           P PP P     P  P PP+P PS  P      P     PP       P     P L  P 
Sbjct: 333 PPPPPPVGFGSPGTPPPPSP-PSFPPHPDFAAPPPPPPPPAADYPTLP----PPPLSQPT 387

Query: 184 AGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLP 215
            G    P P     PPPPP    DG P  P P
Sbjct: 388 GGAPPPPPPPPPPGPPPPPFTGADGQPAIPPP 419



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 18/81 (22%)

Query: 145 PSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPH 204
           PS  P AP LG             P P+  ++P    P       P P+ G+ PPPPP  
Sbjct: 297 PSHPPPAPPLGSP-----------PGPKPGFAPPPAPPPP-----PPPMIGIPPPPPPVG 340

Query: 205 RQDGAPKAPLPPPPAFWRPWP 225
              G+P  P PP P  + P P
Sbjct: 341 F--GSPGTPPPPSPPSFPPHP 359



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 35/101 (34%), Positives = 38/101 (37%), Gaps = 10/101 (9%)

Query: 130 PPRPKPVDPRPPAPRPSLD----PAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAG 185
           PP P+      P+P  S D    P A    P  +QR     G P      SPS   P   
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAG-PKRSSVVSPSHPPPAPP 305

Query: 186 DSGAPAPLTGLLP---PPPPPHRQDGAPKAPLPPPPAFWRP 223
               P P  G  P   PPPPP    G P  P PPP  F  P
Sbjct: 306 LGSPPGPKPGFAPPPAPPPPPPPMIGIP--PPPPPVGFGSP 344



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 28/91 (30%), Positives = 31/91 (34%), Gaps = 20/91 (21%)

Query: 125 YLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRA 184
           +  P PP P P    P  P P L  + P  G      PP   G P P          P  
Sbjct: 361 FAAPPPPPPPPAADYPTLPPPPL--SQPTGGAPPPPPPPPPPGPPPP----------PFT 408

Query: 185 GDSGAPAPLTGLLPPPPPPHRQDGAPKAPLP 215
           G  G PA         PPP      PK+ LP
Sbjct: 409 GADGQPA--------IPPPLSDTTKPKSSLP 431



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 18/56 (32%), Positives = 22/56 (39%)

Query: 130 PPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAG 185
           PP P P  P PP P  +     PA+ P L          P+   A S  L + R G
Sbjct: 392 PPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQG 447


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 35/97 (36%), Positives = 39/97 (40%), Gaps = 9/97 (9%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP PR  + P  P  G  +   PP     +    P P     P    
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1190

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPP 218
            P  G    P PL G   PPPPP    G P AP PP P
Sbjct: 1191 PGVGIP-PPPPLPGAGIPPPPPLPGMGIPPAPAPPLP 1226



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 36/100 (36%), Positives = 41/100 (41%), Gaps = 16/100 (16%)

Query: 128  PKPPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRA 184
            P PP P P   + P PP P   + P  P  G  +   PP+      P  A  P    P A
Sbjct: 909  PPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL------PGAAIPPPPPLPGA 962

Query: 185  GDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            G    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 963  GIP-LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 36/103 (34%), Positives = 41/103 (39%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P PR    P    
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1158 PGAG-IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 35/103 (33%), Positives = 41/103 (39%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G+  PPPPP    G P  P      +PPPP
Sbjct: 1092 PGAG-IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1133



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 35/103 (33%), Positives = 41/103 (39%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP  + G P  P      +PPPP
Sbjct: 1125 PGAGIP-PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP 1166



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 35/103 (33%), Positives = 40/103 (38%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            PR G    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1147 PRVG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1188



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 36/103 (34%), Positives = 41/103 (39%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPPVHQGH-----PSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G A+   PP+         P P     P    
Sbjct: 922  PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 982  PGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 35/103 (33%), Positives = 40/103 (38%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 977  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1036

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1037 PGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 35/103 (33%), Positives = 40/103 (38%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 988  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1048 PGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 35/103 (33%), Positives = 40/103 (38%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 999  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1059 PGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1100



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 35/103 (33%), Positives = 41/103 (39%), Gaps = 13/103 (12%)

Query: 128  PKPPRPKP-VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            P PP P   + P PP P  ++ P  P  G  +   PP     +    P P     P    
Sbjct: 933  PLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 993  PGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1034



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 34/98 (34%), Positives = 39/98 (39%), Gaps = 14/98 (14%)

Query: 128  PKPPRP-KPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGD 186
            P PP P   + P PP P   + P  P  G  +   PP+      P     P    P AG 
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL------PGAGIPPPPPLPGAG- 1073

Query: 187  SGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
               P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1074 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 35/103 (33%), Positives = 40/103 (38%), Gaps = 15/103 (14%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            P AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1114 PGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 36/104 (34%), Positives = 40/104 (38%), Gaps = 11/104 (10%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPP-----VHQGHPSPRCAWSPSLCS 181
            PP P P   + P PP P   + P  P  G  +   PP     +    P P     P    
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069

Query: 182  PRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP 225
            P AG    P PL G   PPPPP    G P  P PP P    P P
Sbjct: 1070 PGAGIP-PPPPLPGAGIPPPPPLPGAGIP--PPPPLPGVGIPPP 1110



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 19/101 (18%)

Query: 128  PKPPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPPVH-QGHPSPRCAWSPSLCSPR 183
            P PP P P   + P PP P   + P  P  G  +   PP+   G P P     P L  P 
Sbjct: 965  PLPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPL--PG 1016

Query: 184  AGDSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
            AG    P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1017 AGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 16/98 (16%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGD 186
            PP P P   + P PP P   + P  P   P +   PP     P P     P    P AG 
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPL--PRVGIPPP----PPLPGAGIPPPPPLPGAG- 1172

Query: 187  SGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
               P PL G+  PPPPP    G P  P      +PPPP
Sbjct: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1210



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 16/99 (16%)

Query: 128  PKPPRPKPVDPRPPA-PRPSLDPAAPALGPALHQRPPVH-QGHPSPRCAWSPSLCSPRAG 185
            P PP P    P PP  P   + P  P  G  +   PP+   G P P     P L  P AG
Sbjct: 955  PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPL--PGAG 1007

Query: 186  DSGAPAPLTGLLPPPPPPHRQDGAPKAP------LPPPP 218
                P PL G   PPPPP    G P  P      +PPPP
Sbjct: 1008 IP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1045



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 32/91 (35%), Positives = 36/91 (39%), Gaps = 10/91 (10%)

Query: 128 PKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDS 187
           P PP P P    P  P  ++    P  G  +   PP     P P     P    P AG  
Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP----PLPGAGIPPPPPLPGAGIL 932

Query: 188 GAPAPLTGLLPPPPPPHRQDGAPKAPLPPPP 218
             P PL G   PPPPP      P A +PPPP
Sbjct: 933 PLP-PLPGAGIPPPPP-----LPGAAIPPPP 957



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 21/113 (18%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALG------PALHQRPPVHQGHPSPRCAWSPSLC 180
            PP P P   + P PP P   + P  P  G      PA    PP     P P    S    
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPL 1245

Query: 181  SPRAGDSGAPAP-LTGLLPPPPPP-------HRQDGAPKAPLPP----PPAFW 221
             P+ G S  P P + G LPPP P        ++  G+ K P+ P     P +W
Sbjct: 1246 LPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYW 1298



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 35/105 (33%), Positives = 42/105 (40%), Gaps = 18/105 (17%)

Query: 130  PPRPKP---VDPRPPAPRPSLDPAAPALGPALHQRPPVH-QGHPSPRCAWSPSLCSPRAG 185
            PP P P   + P PP P   + P  P  G  +   PP+   G P P     P +  P A 
Sbjct: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL--PGMGIPPAP 1221

Query: 186  DSGAPAPLTGLLPPP------PPPHRQDGAPKAPLP------PPP 218
                P P TG+ PPP      PP   Q G+   P P      PPP
Sbjct: 1222 APPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 17/81 (20%)

Query: 140 PPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTG--LL 197
           PP P      + P LG      PP+    P       PS   P+      P PL G  +L
Sbjct: 859 PPLPCTESSSSMPGLGMVPPPPPPL----PGMTVPTLPSTAIPQ------PPPLQGTEML 908

Query: 198 PPPPPPHRQDGAPKAPLPPPP 218
           PPPPPP      P A +PPPP
Sbjct: 909 PPPPPP-----LPGAGIPPPP 924


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 39/106 (36%), Positives = 42/106 (39%), Gaps = 16/106 (15%)

Query: 130 PPRP-KPVDPRP--------PAPRPSLDPAAPALGPALHQRPPVHQGHPS---PRCAWSP 177
           PPRP KP  P P        P PRP      P+ G    Q PP H G P    P+    P
Sbjct: 198 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKP 257

Query: 178 SLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRP 223
               P     G P P      P PPP    G P+ P PPPP   RP
Sbjct: 258 QRPPPPGRPQGPPPPGGNPQQPLPPP---AGKPQGP-PPPPQGGRP 299



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 38/112 (33%), Positives = 42/112 (37%), Gaps = 18/112 (16%)

Query: 130 PPRP-KPVDPRP--------PAPRPSLDPAAPALGPALHQRPPVHQGHPS---PRCAWSP 177
           PPRP KP  P P        P PRP      P  G    Q PP H G P    P+     
Sbjct: 135 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQS 194

Query: 178 SLCSPRAGDSGAPAPLTG--LLPPPPPPHRQDGAP----KAPLPPPPAFWRP 223
               PR G    P P  G     PPP P + +G P      P  PPP   +P
Sbjct: 195 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKP 246



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 37/114 (32%), Positives = 41/114 (35%), Gaps = 22/114 (19%)

Query: 130 PPRP-KPVDPRP--------PAPRPSLDPAAPALGPALHQRPPVHQGHPS---PRCAWSP 177
           PPRP KP  P P        P PRP      P  G    Q PP   G P    P+     
Sbjct: 72  PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 131

Query: 178 SLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLP--------PPPAFWRP 223
               PR G    P P  G     PPP  + G P+ P P        PPP   +P
Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQGPPP--RPGKPEGPPPQGGNQSQGPPPHPGKP 183



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 17/101 (16%)

Query: 131 PRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAP 190
           P P+P  P  P P+       P   P   + PP   G+ S      P    PR G    P
Sbjct: 113 PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ----GP---PPRPGKPEGP 165

Query: 191 APLTGLLPPPPPPHRQDGAPKAPLP--------PPPAFWRP 223
            P  G     PPPH   G P+ P P        PPP   +P
Sbjct: 166 PPQGGNQSQGPPPH--PGKPEGPPPQGGNQSQGPPPRPGKP 204



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/114 (29%), Positives = 39/114 (34%), Gaps = 22/114 (19%)

Query: 130 PPRPKPVDPRPPA---------PRPSLDPAAPALGPALHQRPPVHQGHPS---PRCAWSP 177
           PP P   + RPP          PRP      P  G    Q PP   G P    P+     
Sbjct: 51  PPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQS 110

Query: 178 SLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLP--------PPPAFWRP 223
               PR G    P P  G     PPP  + G P+ P P        PPP   +P
Sbjct: 111 QGPPPRPGKPEGPPPQGGNQSQGPPP--RPGKPEGPPPQGGNQSQGPPPRPGKP 162



 Score = 34.3 bits (77), Expect = 0.088
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 7/76 (9%)

Query: 127 RPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGD 186
           +P+ P P P  P+ P P+    P  P   P   Q PP   G+P         L  P    
Sbjct: 235 KPQGPPPHPGKPQGPPPQEGNKPQRPP-PPGRPQGPPPPGGNPQQ------PLPPPAGKP 287

Query: 187 SGAPAPLTGLLPPPPP 202
            G P P  G  P  PP
Sbjct: 288 QGPPPPPQGGRPHRPP 303


>gi|32483397 dopamine receptor D4 [Homo sapiens]
          Length = 419

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 38/102 (37%), Positives = 42/102 (41%), Gaps = 10/102 (9%)

Query: 122 LHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCA-WSPSLC 180
           LHG    +P  P P  P PPAPR   DP  P   P     P + +G   P CA  +PSL 
Sbjct: 230 LHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAP---PAPGLPRGPCGPDCAPAAPSLP 286

Query: 181 SPRAGDSGAPAPLTGLLPPP-----PPPHRQDGAPKAPLPPP 217
               G   AP P  GL P P      PP     A   P  PP
Sbjct: 287 QDPCGPDCAP-PAPGLPPDPCGSNCAPPDAVRAAALPPQTPP 327


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 32/114 (28%)

Query: 131 PRPKPVDPRPPAP-------------------RPSLDPAAPALGPALHQRPPVHQGHPSP 171
           P P P  P PPAP                    PS  PA P  GP   +  P+    P+P
Sbjct: 127 PPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP--GPRAQRAAPLAAPPPAP 184

Query: 172 RCAWSPSLCSPRAGDSGAPAPLTGL----LPPPP----PPHRQDGAPKAPLPPP 217
               +P   +P AG   AP P        LPPPP    PP +Q   P  P PPP
Sbjct: 185 A---APPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPP 235



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 127 RPKPPRPKPVDPRPP-APRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAG 185
           R +PPR     P PP APR +   AA A  P     PP     P+P  A +P+  +PRA 
Sbjct: 98  RVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPP----PAPVAAAAPAR-APRAA 152

Query: 186 DSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA 219
            + A AP     P  P P  Q  AP A  PP PA
Sbjct: 153 AAAATAP-PSPGPAQPGPRAQRAAPLAAPPPAPA 185



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 38/133 (28%), Positives = 44/133 (33%), Gaps = 21/133 (15%)

Query: 74  PPGVPRSPVQDAEALASCYLSGFRECLLRLAA--FAHDASPAARAQLFSALHGYLRPKPP 131
           PP  P  P   A   A+      R       A      A P  RAQ  + L     P P 
Sbjct: 127 PPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAP-PPAPA 185

Query: 132 RPKPVDPRPPAPRPSLDPAAPALGPAL-----------HQRPPVHQGHPSPRCAWSPSLC 180
            P  V P P  PR +  PA  A  P L            Q+PP  Q  P P         
Sbjct: 186 APPAVAP-PAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGG------ 238

Query: 181 SPRAGDSGAPAPL 193
           + RAG +  P  L
Sbjct: 239 AVRAGGAARPVSL 251


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,267,104
Number of Sequences: 37866
Number of extensions: 1119911
Number of successful extensions: 23951
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 597
Number of HSP's successfully gapped in prelim test: 1346
Number of HSP's that attempted gapping in prelim test: 9263
Number of HSP's gapped (non-prelim): 9220
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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