Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 109689723
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109689723 abl interactor 2 [Homo sapiens]
(475 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109689723 abl interactor 2 [Homo sapiens] 969 0.0
gi|61743948 abl-interactor 1 isoform d [Homo sapiens] 706 0.0
gi|61743944 abl-interactor 1 isoform b [Homo sapiens] 704 0.0
gi|61743942 abl-interactor 1 isoform a [Homo sapiens] 692 0.0
gi|61743946 abl-interactor 1 isoform c [Homo sapiens] 650 0.0
gi|7705981 NESH protein isoform 1 [Homo sapiens] 272 6e-73
gi|206597502 NESH protein isoform 2 [Homo sapiens] 263 3e-70
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 70 4e-12
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 70 4e-12
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 70 4e-12
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s... 68 2e-11
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 64 3e-10
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 64 3e-10
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 64 4e-10
gi|55956916 myosin IE [Homo sapiens] 63 5e-10
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 62 9e-10
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 62 9e-10
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 62 9e-10
gi|20357552 cortactin isoform a [Homo sapiens] 60 4e-09
gi|20357556 cortactin isoform b [Homo sapiens] 60 4e-09
gi|27544941 myosin IF [Homo sapiens] 60 4e-09
gi|18959210 WIRE protein [Homo sapiens] 60 6e-09
gi|46094081 development and differentiation enhancing factor 1 [... 59 1e-08
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 59 1e-08
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom... 58 2e-08
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 58 2e-08
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 58 2e-08
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 58 2e-08
gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ... 58 2e-08
gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 58 2e-08
>gi|109689723 abl interactor 2 [Homo sapiens]
Length = 475
Score = 969 bits (2506), Expect = 0.0
Identities = 475/475 (100%), Positives = 475/475 (100%)
Query: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
Query: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPM 180
THKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPM
Sbjct: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPM 180
Query: 181 SGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGS 240
SGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGS
Sbjct: 181 SGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGS 240
Query: 241 SGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGG 300
SGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGG
Sbjct: 241 SGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGG 300
Query: 301 SLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENI 360
SLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENI
Sbjct: 301 SLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENI 360
Query: 361 SDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVA 420
SDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVA
Sbjct: 361 SDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVA 420
Query: 421 IYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE 475
IYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE
Sbjct: 421 IYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE 475
>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
Length = 476
Score = 706 bits (1821), Expect = 0.0
Identities = 358/486 (73%), Positives = 406/486 (83%), Gaps = 21/486 (4%)
Query: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
MAELQMLLEEEIP G+RAL +SY NL RVADYCENNYIQ+ DK++ALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAY IN LANNVLQ+LDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK-VSTQNMKMGGLPRTTPPTQKPPSPP 179
THKIIAPAN+ERPVRYIRKPIDYT+LDD+GHGVK + Q + G L RT PPTQKPPSPP
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPP 180
Query: 180 MSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSG 239
MSG+GTLGR++PY+TLEPV+PP VPNDY+ SP R SQ SP RTAS+NQR RT+ SG
Sbjct: 181 MSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRTH--SG 236
Query: 240 SSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHP-----VQFYSMNRPASRHT 294
SSGG S SRENSGS S+G+PIAVPTPSPP++ P P Q+ +M R SRH
Sbjct: 237 SSGG------SGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHN 290
Query: 295 PPTIG-GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFV 353
T S YRR PS+T+Q S Q +NGGP YSQN +S+APPPP + Q+TPQ+PL GFV
Sbjct: 291 STTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFV 350
Query: 354 ARVQENISDT---PPPPPPVEEPVFDESPPPPPPPE-DYEEEEAAVVEYSDPYAEEDPPW 409
ARVQENI+D+ PPPPPP + P+FD+SPPPPPPP DYE+EEAAVV+Y+DPYA+ DP W
Sbjct: 351 ARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAW 410
Query: 410 APRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVES 469
AP++Y+EKVVAIYDYTKDK+DELSF EGAIIYVIKKNDDGWYEGV N VTGLFPGNYVES
Sbjct: 411 APKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVES 470
Query: 470 IMHYSE 475
IMHY++
Sbjct: 471 IMHYTD 476
>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
Length = 481
Score = 704 bits (1816), Expect = 0.0
Identities = 358/491 (72%), Positives = 406/491 (82%), Gaps = 26/491 (5%)
Query: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
MAELQMLLEEEIP G+RAL +SY NL RVADYCENNYIQ+ DK++ALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAY IN LANNVLQ+LDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK------VSTQNMKMGGLPRTTPPTQK 174
THKIIAPAN+ERPVRYIRKPIDYT+LDD+GHGVK + Q + G L RT PPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 175 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 234
PPSPPMSG+GTLGR++PY+TLEPV+PP VPNDY+ SP R SQ SP RTAS+NQR RT
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT 238
Query: 235 YSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHP-----VQFYSMNRP 289
+ SGSSGG S SRENSGS S+G+PIAVPTPSPP++ P P Q+ +M R
Sbjct: 239 H--SGSSGG------SGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQ 290
Query: 290 ASRHTPPTIG-GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLP 348
SRH T S YRR PS+T+Q S Q +NGGP YSQN +S+APPPP + Q+TPQ+P
Sbjct: 291 ISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIP 350
Query: 349 LMGFVARVQENISDT---PPPPPPVEEPVFDESPPPPPPPE-DYEEEEAAVVEYSDPYAE 404
L GFVARVQENI+D+ PPPPPP + P+FD+SPPPPPPP DYE+EEAAVV+Y+DPYA+
Sbjct: 351 LTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYAD 410
Query: 405 EDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPG 464
DP WAP++Y+EKVVAIYDYTKDK+DELSF EGAIIYVIKKNDDGWYEGV N VTGLFPG
Sbjct: 411 GDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPG 470
Query: 465 NYVESIMHYSE 475
NYVESIMHY++
Sbjct: 471 NYVESIMHYTD 481
>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
Length = 508
Score = 692 bits (1785), Expect = 0.0
Identities = 359/518 (69%), Positives = 408/518 (78%), Gaps = 53/518 (10%)
Query: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
MAELQMLLEEEIP G+RAL +SY NL RVADYCENNYIQ+ DK++ALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAY IN LANNVLQ+LDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK------VSTQNMKMGGLPRTTPPTQK 174
THKIIAPAN+ERPVRYIRKPIDYT+LDD+GHGVK + Q + G L RT PPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 175 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 234
PPSPPMSG+GTLGR++PY+TLEPV+PP VPNDY+ SP R SQ SP RTAS+NQR RT
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT 238
Query: 235 YSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGH--------------- 279
+ SGSSGG S SRENSGS S+G+PIAVPTPSPP++ P +
Sbjct: 239 H--SGSSGG------SGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPL 290
Query: 280 ----PV-------------QFYSMNRPASRHTPPTIG-GSLPYRRPPSITSQTSLQNQMN 321
PV Q+ +M R SRH T S YRR PS+T+Q S Q +N
Sbjct: 291 APLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVN 350
Query: 322 GGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDT---PPPPPPVEEPVFDES 378
GGP YSQN +S+APPPP + Q+TPQ+PL GFVARVQENI+D+ PPPPPP + P+FD+S
Sbjct: 351 GGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDS 410
Query: 379 PPPPPPPE-DYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEG 437
PPPPPPP DYE+EEAAVV+Y+DPYA+ DP WAP++Y+EKVVAIYDYTKDK+DELSF EG
Sbjct: 411 PPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEG 470
Query: 438 AIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE 475
AIIYVIKKNDDGWYEGV N VTGLFPGNYVESIMHY++
Sbjct: 471 AIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 508
>gi|61743946 abl-interactor 1 isoform c [Homo sapiens]
Length = 452
Score = 650 bits (1677), Expect = 0.0
Identities = 337/488 (69%), Positives = 381/488 (78%), Gaps = 49/488 (10%)
Query: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
MAELQMLLEEEIP G+RAL +SY NL RVADYCENNYIQ+ DK++ALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAY IN LANNVLQ+LDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK------VSTQNMKMGGLPRTTPPTQK 174
THKIIAPAN+ERPVRYIRKPIDYT+LDD+GHGVK + Q + G L RT PPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 175 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 234
PPSPPMSG+GTLGR++PY+TLEPV+PP VPNDY+ SP R SQ SP RTAS+NQR RT
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT 238
Query: 235 YSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHP-----VQFYSMNRP 289
+ SGSSGG S SRENSGS S+G+PIAVPTPSPP++ P P Q+ +M R
Sbjct: 239 H--SGSSGG------SGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQ 290
Query: 290 ASRHTPPTIG-GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLP 348
SRH T S YRR PS+T+Q S Q +NGGP YSQN ++ +P P
Sbjct: 291 ISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTP----------- 339
Query: 349 LMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPE-DYEEEEAAVVEYSDPYAEEDP 407
PPPPPP + P+FD+SPPPPPPP DYE+EEAAVV+Y+DPYA+ DP
Sbjct: 340 ---------------PPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDP 384
Query: 408 PWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYV 467
WAP++Y+EKVVAIYDYTKDK+DELSF EGAIIYVIKKNDDGWYEGV N VTGLFPGNYV
Sbjct: 385 AWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 444
Query: 468 ESIMHYSE 475
ESIMHY++
Sbjct: 445 ESIMHYTD 452
>gi|7705981 NESH protein isoform 1 [Homo sapiens]
Length = 366
Score = 272 bits (695), Expect = 6e-73
Identities = 183/469 (39%), Positives = 240/469 (51%), Gaps = 107/469 (22%)
Query: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
MAELQ L E EIP GR AL +++ L RVADYCE+NY+Q+ DK++ALEET A+TTQ+LAS
Sbjct: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
Query: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAY + LA + L+MLD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +
Sbjct: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
Query: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK-VSTQNMKMGGLPRTTPPTQKPPSPP 179
K+IAP NL Y R+P+++ LDDIGHG+K +STQ + G L R + K P+ P
Sbjct: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSR---KSIKAPATP 177
Query: 180 MSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSG 239
S TLGR P R EPV PVVP+ +
Sbjct: 178 AS--ATLGR--PPRIPEPVHLPVVPDGRL------------------------------- 202
Query: 240 SSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIG 299
S S SS +S+ G G PTP + P P+ P+S PP
Sbjct: 203 -SAASSASSLASAGSAEGVG------GAPTPKGQAAPPAPPL-------PSSLDPPPPPA 248
Query: 300 GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQEN 359
++RPP++ L+PPPP +LPL
Sbjct: 249 AVEVFQRPPTLE--------------------ELSPPPPD-----EELPLP--------- 274
Query: 360 ISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVV 419
D PPPPP DE PPPPP + ++P W P SYLEKVV
Sbjct: 275 -LDLPPPPPLDG----DELGLPPPPP---------------GFGPDEPSWVPASYLEKVV 314
Query: 420 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
+Y YT K++ELSF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 315 TLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
>gi|206597502 NESH protein isoform 2 [Homo sapiens]
Length = 360
Score = 263 bits (671), Expect = 3e-70
Identities = 182/469 (38%), Positives = 237/469 (50%), Gaps = 113/469 (24%)
Query: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
MAELQ L E EIP GR AL +++ L RVADYCE+NY+Q+ DK++ALEET A+TTQ+LAS
Sbjct: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
Query: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAY + LA + L+MLD+Q + LR++E ++ V++H EKVARREIG L T +
Sbjct: 61 VAYQVGNLAGHTLRMLDLQGAALRQVE------ARMVNMHMEKVARREIGTLATVQRLPP 114
Query: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK-VSTQNMKMGGLPRTTPPTQKPPSPP 179
K+IAP NL Y R+P+++ LDDIGHG+K +STQ + G L R + K P+ P
Sbjct: 115 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSR---KSIKAPATP 171
Query: 180 MSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSG 239
S TLGR P R EPV PVVP+ +
Sbjct: 172 AS--ATLGR--PPRIPEPVHLPVVPDGRL------------------------------- 196
Query: 240 SSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIG 299
S S SS +S+ G G PTP + P P+ P+S PP
Sbjct: 197 -SAASSASSLASAGSAEGVG------GAPTPKGQAAPPAPPL-------PSSLDPPPPPA 242
Query: 300 GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQEN 359
++RPP++ L+PPPP +LPL
Sbjct: 243 AVEVFQRPPTLE--------------------ELSPPPPD-----EELPLP--------- 268
Query: 360 ISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVV 419
D PPPPP DE PPPPP + ++P W P SYLEKVV
Sbjct: 269 -LDLPPPPPLDG----DELGLPPPPP---------------GFGPDEPSWVPASYLEKVV 308
Query: 420 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
+Y YT K++ELSF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 309 TLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 357
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 70.1 bits (170), Expect = 4e-12
Identities = 29/52 (55%), Positives = 41/52 (78%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
+V+A+YDY + EDELSF +G +I V+ K+D W++G +NGVTGLFP NYV+
Sbjct: 1104 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1155
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 386 EDYEEEEAAVVEYS----DPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIY 441
E +EEE E D E+ S L A+Y + DE+SF G II
Sbjct: 699 EKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQ 758
Query: 442 VIKKN--DDGWYEGVMNGVTGLFPGNYVESI 470
V +K + GW G G G FP NYVE +
Sbjct: 759 VDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 789
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 407 PPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNY 466
P A S E+ +A+Y Y+ + +L+F EG I V +K D W+ G + +G+FP NY
Sbjct: 948 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK-DGEWWTGSIGDRSGIFPSNY 1006
Query: 467 VE 468
V+
Sbjct: 1007 VK 1008
Score = 36.6 bits (83), Expect = 0.051
Identities = 18/54 (33%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
K A+ +T K++ L+F + II V+++ ++ W+ G ++G G FP +YV+ I
Sbjct: 875 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 927
Score = 35.0 bits (79), Expect = 0.15
Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 424 YTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG-----VTGLFPGNYVESIMHYSE 475
Y ++LS G +I ++KKN GW++G + G FP ++V+ + SE
Sbjct: 1037 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSE 1093
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 70.1 bits (170), Expect = 4e-12
Identities = 29/52 (55%), Positives = 41/52 (78%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
+V+A+YDY + EDELSF +G +I V+ K+D W++G +NGVTGLFP NYV+
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1182
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 386 EDYEEEEAAVVEYS----DPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIY 441
E +EEE E D E+ S L A+Y + DE+SF G II
Sbjct: 726 EKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQ 785
Query: 442 VIKKN--DDGWYEGVMNGVTGLFPGNYVESI 470
V +K + GW G G G FP NYVE +
Sbjct: 786 VDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 407 PPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNY 466
P A S E+ +A+Y Y+ + +L+F EG I V +K D W+ G + +G+FP NY
Sbjct: 975 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK-DGEWWTGSIGDRSGIFPSNY 1033
Query: 467 VE 468
V+
Sbjct: 1034 VK 1035
Score = 36.6 bits (83), Expect = 0.051
Identities = 18/54 (33%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
K A+ +T K++ L+F + II V+++ ++ W+ G ++G G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954
Score = 35.0 bits (79), Expect = 0.15
Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 424 YTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG-----VTGLFPGNYVESIMHYSE 475
Y ++LS G +I ++KKN GW++G + G FP ++V+ + SE
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSE 1120
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 70.1 bits (170), Expect = 4e-12
Identities = 29/52 (55%), Positives = 41/52 (78%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
+V+A+YDY + EDELSF +G +I V+ K+D W++G +NGVTGLFP NYV+
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1182
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 386 EDYEEEEAAVVEYS----DPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIY 441
E +EEE E D E+ S L A+Y + DE+SF G II
Sbjct: 726 EKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQ 785
Query: 442 VIKKN--DDGWYEGVMNGVTGLFPGNYVESI 470
V +K + GW G G G FP NYVE +
Sbjct: 786 VDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 407 PPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNY 466
P A S E+ +A+Y Y+ + +L+F EG I V +K D W+ G + +G+FP NY
Sbjct: 975 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK-DGEWWTGSIGDRSGIFPSNY 1033
Query: 467 VE 468
V+
Sbjct: 1034 VK 1035
Score = 36.6 bits (83), Expect = 0.051
Identities = 18/54 (33%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
K A+ +T K++ L+F + II V+++ ++ W+ G ++G G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954
Score = 35.0 bits (79), Expect = 0.15
Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 424 YTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG-----VTGLFPGNYVESIMHYSE 475
Y ++LS G +I ++KKN GW++G + G FP ++V+ + SE
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSE 1120
>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
sapiens]
Length = 486
Score = 68.2 bits (165), Expect = 2e-11
Identities = 48/159 (30%), Positives = 66/159 (41%), Gaps = 37/159 (23%)
Query: 347 LPLMGFVARVQENISDTPPPPPPV-------EEPVFDESPPPPPPPEDYEEEEAAVVEYS 399
+PL+ + E+ + P PP EEPV++ P P P PE E + VE
Sbjct: 325 VPLLPIRQTLPEDNEEPPALPPRTLEGLQVEEEPVYEAEPEPEPEPEPEPENDYEDVEEM 384
Query: 400 DPYAEEDPPWAP-RSYLE-----------------------------KVVAIYDYTKDKE 429
D + +ED P LE VA+YDY +
Sbjct: 385 DRHEQEDEPEGDYEEVLEPEDSSFSSALAGSSGCPAGAGAGAVALGISAVALYDYQGEGS 444
Query: 430 DELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
DELSF +I I+ D+GW+ G +G GLFP NYV+
Sbjct: 445 DELSFDPDDVITDIEMVDEGWWRGRCHGHFGLFPANYVK 483
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 63.9 bits (154), Expect = 3e-10
Identities = 26/52 (50%), Positives = 37/52 (71%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
+V+ +YDYT +DEL+F +G II V+ K D W++G +NG GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210
Score = 49.7 bits (117), Expect = 6e-06
Identities = 21/52 (40%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Query: 416 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYV 467
E+ +A+Y Y ++ +L+FQ+G +I V KK+ D W+ G + G+FP NYV
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNYV 1055
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 12/95 (12%)
Query: 388 YEEEEAAVVEYSDPY--AEEDPPWAPRSYLEKVV---AIYDYTKDKEDELSFQEGAIIYV 442
++ +E A P+ AE+ P KVV A+Y + DE++ Q G I+ V
Sbjct: 710 HQHQEPAKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMV 769
Query: 443 -------IKKNDDGWYEGVMNGVTGLFPGNYVESI 470
+ + GW G + G TG FP NY E I
Sbjct: 770 KGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 37.7 bits (86), Expect = 0.023
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 421 IYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG-----VTGLFPGNYVE 468
I YT ++L+ G +I + KKN GW+EG + G FP NYV+
Sbjct: 1082 IASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1134
Score = 36.6 bits (83), Expect = 0.051
Identities = 17/51 (33%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Query: 420 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
A+Y + K++ L+F + +I V+++ D W+ G + G G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 63.9 bits (154), Expect = 3e-10
Identities = 26/52 (50%), Positives = 37/52 (71%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
+V+ +YDYT +DEL+F +G II V+ K D W++G +NG GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210
Score = 49.7 bits (117), Expect = 6e-06
Identities = 21/52 (40%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Query: 416 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYV 467
E+ +A+Y Y ++ +L+FQ+G +I V KK+ D W+ G + G+FP NYV
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNYV 1055
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 12/95 (12%)
Query: 388 YEEEEAAVVEYSDPY--AEEDPPWAPRSYLEKVV---AIYDYTKDKEDELSFQEGAIIYV 442
++ +E A P+ AE+ P KVV A+Y + DE++ Q G I+ V
Sbjct: 710 HQHQEPAKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMV 769
Query: 443 -------IKKNDDGWYEGVMNGVTGLFPGNYVESI 470
+ + GW G + G TG FP NY E I
Sbjct: 770 KGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 37.7 bits (86), Expect = 0.023
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 421 IYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG-----VTGLFPGNYVE 468
I YT ++L+ G +I + KKN GW+EG + G FP NYV+
Sbjct: 1082 IASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1134
Score = 36.6 bits (83), Expect = 0.051
Identities = 17/51 (33%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Query: 420 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
A+Y + K++ L+F + +I V+++ D W+ G + G G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969
>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
Length = 888
Score = 63.5 bits (153), Expect = 4e-10
Identities = 54/194 (27%), Positives = 77/194 (39%), Gaps = 15/194 (7%)
Query: 285 SMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVT 344
S NR + +PP + S I+ + L S + + PPP S +
Sbjct: 318 SQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQVHISTTGLIVTPPPSSPVTTG 377
Query: 345 PQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAA------VVEY 398
P V + PP PPP P+ + PP AA +
Sbjct: 378 PSFTFPSDVPYQAALGTLNPPLPPP---PLLAATVLASTPPGATAAAAAAGMGPRPMAGS 434
Query: 399 SDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEG--VMN 456
+D A P P Y VAIY YT KEDEL ++G + V ++ DGW++G +
Sbjct: 435 TDQIAHLRPQTRPSVY----VAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHT 490
Query: 457 GVTGLFPGNYVESI 470
G+FPGNYV +
Sbjct: 491 SKIGVFPGNYVAPV 504
Score = 60.1 bits (144), Expect = 4e-09
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 13/97 (13%)
Query: 376 DESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQ 435
D + P PPP V+ S P E+ + Y E EL +
Sbjct: 803 DSAVPIAPPPRQACSSLGPVLNESRPVV-----------CERHRVVVSYPPQSEAELELK 851
Query: 436 EGAIIYVIKKNDDGWYEGVM--NGVTGLFPGNYVESI 470
EG I++V KK +DGW++G + NG TGLFPG++VE+I
Sbjct: 852 EGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI 888
Score = 49.7 bits (117), Expect = 6e-06
Identities = 23/64 (35%), Positives = 36/64 (56%)
Query: 407 PPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNY 466
PP L A+Y+Y + +L F +G II + ++ D+ WY G +NG+ G FP N+
Sbjct: 128 PPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNF 187
Query: 467 VESI 470
V+ I
Sbjct: 188 VQII 191
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/53 (41%), Positives = 34/53 (64%), Gaps = 4/53 (7%)
Query: 420 AIYDY-TKDKE---DELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
A+YD+ KDKE D L F + ++ VI++ D+ W EG++ G+FP +YVE
Sbjct: 203 ALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVE 255
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 63.2 bits (152), Expect = 5e-10
Identities = 55/201 (27%), Positives = 83/201 (41%), Gaps = 20/201 (9%)
Query: 288 RPASRHTPPTIGGSLPYRRPPSITSQTSLQNQ-MNGGPFYSQNPVSLAPPPPSILQ---- 342
+P+++ +IG LP P T + + QN + G + PV APPPP Q
Sbjct: 910 KPSNKVLQVSIGPGLPKNSRP--TRRNTTQNTGYSSGTQNANYPVRAAPPPPGYHQNGVI 967
Query: 343 ---VTPQLPLMGFVARVQENI-SDTPPPPPPVEEPVFDESPPPPPPPEDY---EEEEAAV 395
P G Q+++ + PP P ++ + P D+ ++ AA
Sbjct: 968 RNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKVPDQGAAG 1027
Query: 396 VEYSDPY------AEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDG 449
V P P+ + + A+Y Y DELSF II +IK++ G
Sbjct: 1028 VRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSG 1087
Query: 450 WYEGVMNGVTGLFPGNYVESI 470
W+ G + G GLFP NYV I
Sbjct: 1088 WWTGRLRGKQGLFPNNYVTKI 1108
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 62.4 bits (150), Expect = 9e-10
Identities = 68/304 (22%), Positives = 107/304 (35%), Gaps = 35/304 (11%)
Query: 197 PVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENS 256
PV PP VP P R+ + +++ R + S S + +SS ++
Sbjct: 346 PVPPPHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHE 405
Query: 257 GSGSVGVPIAVPTPSPPSVFPGH-PVQFYSMNR-PASRHTPPTIGGSLPYRRPPSITS-- 312
P TP+P PG P+ + S PP G P R P+++
Sbjct: 406 RP-----PPLPTTPTPVPREPGRKPLSSSRLGEVTGSPSPPPRSGAPTPSSRAPALSPTR 460
Query: 313 ---------QTSLQNQMNGGPFYS-------QNPVSLAPPPPSILQVTPQLPLMG----- 351
Q N Y + P+S A + P +G
Sbjct: 461 PPKKPLDYVQDHSSGVFNEASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGL 520
Query: 352 ---FVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDP--YAEED 406
+R D P + + SP P +D E + +D A +
Sbjct: 521 GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRE 580
Query: 407 PPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNY 466
P A+YD+ ELSF++G +Y+++K D WYEG +G G+FP +Y
Sbjct: 581 RRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISY 640
Query: 467 VESI 470
VE +
Sbjct: 641 VEKL 644
Score = 57.0 bits (136), Expect = 4e-08
Identities = 75/315 (23%), Positives = 111/315 (35%), Gaps = 44/315 (13%)
Query: 172 TQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVP---SPTRNMAPSQQS------- 221
T P PP SG T +P L P RPP P DYV S N A QS
Sbjct: 435 TGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYVQDHSSGVFNEASLYQSSIDRSLE 492
Query: 222 -PVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVP--IAVPTPSPPSVFPG 278
P+ +AS+ R S + G S + G V +P T S S P
Sbjct: 493 RPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPS 552
Query: 279 HPVQFYSMNRPASRHTPPT-IGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPP 337
P + P S + T +G S P R + + + F +Q L+
Sbjct: 553 SPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYD--FKAQTSKELSFKK 610
Query: 338 PSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVE 397
+ + ++ + + P P P PPPP E
Sbjct: 611 GDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPAQPGE------- 663
Query: 398 YSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG 457
+ + +A Y++ D ELS ++G + ++K+ D WYEG + G
Sbjct: 664 -----------------IGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPG 706
Query: 458 VT--GLFPGNYVESI 470
G+FP +YVE +
Sbjct: 707 TNRQGIFPVSYVEVV 721
Score = 55.8 bits (133), Expect = 8e-08
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Query: 377 ESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQE 436
E P PP P Y + + + P + E A+Y+YT EDEL +E
Sbjct: 729 EDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRE 788
Query: 437 GAIIYVIKKNDDGWYEGVMNGVT--GLFPGNYVESI 470
+I V++K DDGW+ G G FPGNYV+ +
Sbjct: 789 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 62.4 bits (150), Expect = 9e-10
Identities = 68/304 (22%), Positives = 107/304 (35%), Gaps = 35/304 (11%)
Query: 197 PVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENS 256
PV PP VP P R+ + +++ R + S S + +SS ++
Sbjct: 253 PVPPPHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHE 312
Query: 257 GSGSVGVPIAVPTPSPPSVFPGH-PVQFYSMNR-PASRHTPPTIGGSLPYRRPPSITS-- 312
P TP+P PG P+ + S PP G P R P+++
Sbjct: 313 RP-----PPLPTTPTPVPREPGRKPLSSSRLGEVTGSPSPPPRSGAPTPSSRAPALSPTR 367
Query: 313 ---------QTSLQNQMNGGPFYS-------QNPVSLAPPPPSILQVTPQLPLMG----- 351
Q N Y + P+S A + P +G
Sbjct: 368 PPKKPLDYVQDHSSGVFNEASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGL 427
Query: 352 ---FVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDP--YAEED 406
+R D P + + SP P +D E + +D A +
Sbjct: 428 GDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRE 487
Query: 407 PPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNY 466
P A+YD+ ELSF++G +Y+++K D WYEG +G G+FP +Y
Sbjct: 488 RRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISY 547
Query: 467 VESI 470
VE +
Sbjct: 548 VEKL 551
Score = 57.0 bits (136), Expect = 4e-08
Identities = 75/315 (23%), Positives = 111/315 (35%), Gaps = 44/315 (13%)
Query: 172 TQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVP---SPTRNMAPSQQS------- 221
T P PP SG T +P L P RPP P DYV S N A QS
Sbjct: 342 TGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYVQDHSSGVFNEASLYQSSIDRSLE 399
Query: 222 -PVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVP--IAVPTPSPPSVFPG 278
P+ +AS+ R S + G S + G V +P T S S P
Sbjct: 400 RPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPS 459
Query: 279 HPVQFYSMNRPASRHTPPT-IGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPP 337
P + P S + T +G S P R + + + F +Q L+
Sbjct: 460 SPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYD--FKAQTSKELSFKK 517
Query: 338 PSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVE 397
+ + ++ + + P P P PPPP E
Sbjct: 518 GDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPAQPGE------- 570
Query: 398 YSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG 457
+ + +A Y++ D ELS ++G + ++K+ D WYEG + G
Sbjct: 571 -----------------IGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPG 613
Query: 458 VT--GLFPGNYVESI 470
G+FP +YVE +
Sbjct: 614 TNRQGIFPVSYVEVV 628
Score = 55.8 bits (133), Expect = 8e-08
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Query: 377 ESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQE 436
E P PP P Y + + + P + E A+Y+YT EDEL +E
Sbjct: 636 EDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRE 695
Query: 437 GAIIYVIKKNDDGWYEGVMNGVT--GLFPGNYVESI 470
+I V++K DDGW+ G G FPGNYV+ +
Sbjct: 696 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731
>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
Length = 882
Score = 62.4 bits (150), Expect = 9e-10
Identities = 82/348 (23%), Positives = 133/348 (38%), Gaps = 49/348 (14%)
Query: 150 GHGVKVSTQNMKMGGLPRTTP------PTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVV 203
G G S LP TTP PT PP+ G+ RHS T R +
Sbjct: 555 GSGSLSSLATATRPALPITTPQAHAQHPTASPPT------GSCLRHSAQPTASQARSTIS 608
Query: 204 PNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGV 263
+ + ++ + SP+RT + R S S S S + ++ +
Sbjct: 609 TAAHSAAQAQDRPTATVSPLRTQNSPSRLPATSLRPHSVVSPQHSHQPPVQMCPRPAIPL 668
Query: 264 PIAVPTPSPPSVFP--------GHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTS 315
A +PP+V G P+ S + P + G L ++ ++
Sbjct: 669 TSAASAITPPNVSAANLNGEAGGGPIGVLSTSSPTNT------GCKLDEKKSEKKEKKSG 722
Query: 316 LQNQMNGGPFY--SQNPVSLAPPPPSILQVTPQLPLMGFVARVQENIS-DTPPPPPPVEE 372
L + G S++P S++P QV L G V ++S P+E
Sbjct: 723 LLKLLAGASTKKKSRSPPSVSPTHDP--QVAVDALLQGAVGPEVSSLSIHGRAGSCPIES 780
Query: 373 PVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEE---------DPPWAPRSYLEKVVAIYD 423
+ P + + + + ++ P + +P PR E+ +
Sbjct: 781 EMQGAMGMEPL----HRKAGSLDLNFTSPSRQAPLSMAAIRPEPKLLPR---ERYRVVVS 833
Query: 424 YTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM--NGVTGLFPGNYVES 469
Y E E+ +EG I++V KK +DGWY+G + NG TGLFPG++VES
Sbjct: 834 YPPQSEAEIELKEGDIVFVHKKREDGWYKGTLQRNGRTGLFPGSFVES 881
Score = 53.9 bits (128), Expect = 3e-07
Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 394 AVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEG 453
AV + E+ P + L +A+Y Y K DEL +G + V++K DGW++G
Sbjct: 445 AVPRAASVSGEQGTPPKVQLPLNVYLALYAYKPQKSDELELHKGEMYRVLEKCQDGWFKG 504
Query: 454 --VMNGVTGLFPGNYVESI 470
+ GV+G+FPGNYV +
Sbjct: 505 ASLRTGVSGVFPGNYVTPV 523
Score = 45.4 bits (106), Expect = 1e-04
Identities = 18/51 (35%), Positives = 30/51 (58%)
Query: 420 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
A+Y Y + +L F +G II + +K D+ WY G ++G G P +Y++ I
Sbjct: 201 ALYSYEGKEPGDLKFNKGDIIVLRRKVDEQWYHGELHGTQGFLPASYIQCI 251
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 4/53 (7%)
Query: 420 AIYDYT-KDKEDE---LSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
A+YD+ KDK+ + L+F + I+ V+++ D+ W EG++ G+FP YVE
Sbjct: 263 ALYDFEMKDKDQDKDCLTFTKDEILTVLRRVDENWAEGMLGDKIGIFPLLYVE 315
>gi|20357552 cortactin isoform a [Homo sapiens]
Length = 550
Score = 60.1 bits (144), Expect = 4e-09
Identities = 50/153 (32%), Positives = 61/153 (39%), Gaps = 22/153 (14%)
Query: 330 PVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYE 389
PVS AP P + P P+ A + +S P EPV+ DY
Sbjct: 403 PVSPAPQPTE--ERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAA------DYR 454
Query: 390 EEE-------AAVVEYSDPYAEEDPPWAPRSYLE-------KVVAIYDYTKDKEDELSFQ 435
E A Y A P +Y E VA+YDY +DE+SF
Sbjct: 455 EASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFD 514
Query: 436 EGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
II I+ DDGW+ GV G GLFP NYVE
Sbjct: 515 PDDIITNIEMIDDGWWRGVCKGRYGLFPANYVE 547
>gi|20357556 cortactin isoform b [Homo sapiens]
Length = 513
Score = 60.1 bits (144), Expect = 4e-09
Identities = 50/153 (32%), Positives = 61/153 (39%), Gaps = 22/153 (14%)
Query: 330 PVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYE 389
PVS AP P + P P+ A + +S P EPV+ DY
Sbjct: 366 PVSPAPQPTE--ERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAA------DYR 417
Query: 390 EEE-------AAVVEYSDPYAEEDPPWAPRSYLE-------KVVAIYDYTKDKEDELSFQ 435
E A Y A P +Y E VA+YDY +DE+SF
Sbjct: 418 EASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFD 477
Query: 436 EGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
II I+ DDGW+ GV G GLFP NYVE
Sbjct: 478 PDDIITNIEMIDDGWWRGVCKGRYGLFPANYVE 510
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 60.1 bits (144), Expect = 4e-09
Identities = 43/160 (26%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
Query: 327 SQNPVSLAPPPPSILQ---VTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPP 383
SQ P AP PP + V P + PP P + P
Sbjct: 939 SQAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRAR 998
Query: 384 PPEDYEEEEAAVVEYSDPYAEED-------------PPWAPRSYLEKVVAIYDYTKDKED 430
PP ++ E V + + P PR++ + A+Y Y D
Sbjct: 999 PPSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVD 1058
Query: 431 ELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
ELSF +I ++ ++ GW++G ++G GLFPGNYVE I
Sbjct: 1059 ELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 59.7 bits (143), Expect = 6e-09
Identities = 73/288 (25%), Positives = 100/288 (34%), Gaps = 57/288 (19%)
Query: 170 PPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVN 229
P Q+P P +S T + PP P R AP P+ ++
Sbjct: 149 PRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPP-------PPGRRANAPPTPLPMHSSKAP 201
Query: 230 QRNRTYSSSGSSGGS-HPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNR 288
NR + G HP G G P P PPS PV +
Sbjct: 202 AYNREKPLPPTPGQRLHP------------GREGPPAPPPVKPPPS-----PVNIRTGPS 244
Query: 289 PASRHTPPTIGGSLPYRRPPSITSQTS---------LQNQMNGGPFYSQNPV-SLAPPPP 338
S PP PYR+PP + + S L + N + PV LAPPPP
Sbjct: 245 GQSLAPPPP-----PYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPP 299
Query: 339 -----SILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEA 393
S+L P P AR + PPPPPPV ++PPPPPP + E
Sbjct: 300 TSASPSLLSNRPPPP-----ARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPP 354
Query: 394 AVVEYSDPYAE-------EDPPWAPRSYLEKVVAIYDYTKDKEDELSF 434
+ + P + PP + + + + + D E + SF
Sbjct: 355 SRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSF 402
Score = 52.0 bits (123), Expect = 1e-06
Identities = 64/225 (28%), Positives = 79/225 (35%), Gaps = 77/225 (34%)
Query: 166 PRTTPPTQKPPSPPMSGKGTLGRH-----SPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQ 220
P PP + PPSP G G+ PYR +PP VPN SPT AP +
Sbjct: 224 PPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYR-----QPPGVPNG-PSSPTNESAP--E 275
Query: 221 SPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHP 280
P R S++++ + G G P PT + PS+ P
Sbjct: 276 LPQRHNSLHRK-----TPGPVRGLAPPP-------------------PTSASPSLLSNRP 311
Query: 281 VQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSI 340
P PP+ G + P PP P +N APPPP
Sbjct: 312 --------PPPARDPPSRGAAPP---PP---------------PPVIRNGARDAPPPP-- 343
Query: 341 LQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPP 385
P + G E S PPPPP P PPPPPPP
Sbjct: 344 ----PPYRMHG-----SEPPSRGKPPPPPSRTPA---GPPPPPPP 376
Score = 42.7 bits (99), Expect = 7e-04
Identities = 55/245 (22%), Positives = 87/245 (35%), Gaps = 38/245 (15%)
Query: 165 LPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVR 224
+P PP PP PP + + R + R ++ + + + + R
Sbjct: 3 IPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNIND---R 59
Query: 225 TASVNQRNRTYSSSGSSGGS----------------HPSSRSSSREN-SGSGSVGVP--- 264
+A + ++ + S SGG+ P EN +G ++ +P
Sbjct: 60 SAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSR 119
Query: 265 IAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGP 324
A P P P S G P +R + P SLP P+ TS T +++ + P
Sbjct: 120 AAAPRP-PVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPP 178
Query: 325 FYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEE--PVFDESPPPP 382
PPPP P PL ++ + P PP P + P + P PP
Sbjct: 179 ----------PPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPP 228
Query: 383 P--PP 385
P PP
Sbjct: 229 PVKPP 233
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/27 (44%), Positives = 14/27 (51%), Gaps = 9/27 (33%)
Query: 364 PPPPPPVEEPVFDESPPPPPPPEDYEE 390
PPPPPP PP PPPP + +
Sbjct: 4 PPPPPP---------PPGPPPPPTFHQ 21
>gi|46094081 development and differentiation enhancing factor 1 [Homo
sapiens]
Length = 1129
Score = 58.9 bits (141), Expect = 1e-08
Identities = 88/364 (24%), Positives = 131/364 (35%), Gaps = 87/364 (23%)
Query: 168 TTPPTQKPPSPPMS-GKGTLGRHSPY----------RTLEPVRPPVVPNDYVPSPTRNMA 216
T+P T+ PP PP + GKG G S TL RPP P + + + +
Sbjct: 784 TSPTTEAPPLPPRNAGKGPTGPPSTLPLSTQTSSGSSTLSKKRPPPPPPGHKRTLSDPPS 843
Query: 217 PSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVF 276
P P +V G+ GG SS+++++ G + T P V
Sbjct: 844 PLPHGPPNKGAVPW--------GNDGGPSSSSKTTNKFE-GLSQQSSTSSAKTALGPRVL 894
Query: 277 PGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPP 336
P P + TI PP I ++S ++ P P PP
Sbjct: 895 PKLPQKVALRKTDHLSLDKATI--------PPEIFQKSSQLAELPQKP-----PPGDLPP 941
Query: 337 PPSILQVTPQL-------------PLMGFVARVQENISDTPPPP-----PP--------V 370
P+ L PQ+ P +G + + +SD PP P PP
Sbjct: 942 KPTELAPKPQIGDLPPKPGELPPKPQLGDLPP-KPQLSDLPPKPQMKDLPPKPQLGDLLA 1000
Query: 371 EEPVFDESPPPPPPPE------------DYEEEEAAVVEYSD------PYAEEDPPWAPR 412
+ D SP P E + + +A + S+ P E P PR
Sbjct: 1001 KSQTGDVSPKAQQPSEVTLKSHPLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPR 1060
Query: 413 SY------LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGV---TGLFP 463
+ +V IYD D +DEL+F EG +I V + D W+ G + G G+FP
Sbjct: 1061 KINTGKNKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFP 1120
Query: 464 GNYV 467
++V
Sbjct: 1121 VSFV 1124
Score = 30.0 bits (66), Expect = 4.8
Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 21/182 (11%)
Query: 112 LTTNKNTSRTHKIIAPANLER-PVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTP 170
L+ +TS + P L + P + + D+ LD ++ ++ ++ LP+ P
Sbjct: 876 LSQQSSTSSAKTALGPRVLPKLPQKVALRKTDHLSLDKATIPPEIFQKSSQLAELPQKPP 935
Query: 171 PTQKPPSP------PMSG-----------KGTLGRHSPYRTLEPVRPPVVPNDYVPSPTR 213
P PP P P G K LG P L + P D P P
Sbjct: 936 PGDLPPKPTELAPKPQIGDLPPKPGELPPKPQLGDLPPKPQLSDLPPKPQMKDLPPKPQL 995
Query: 214 N--MAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVP-TP 270
+A SQ V + T S + SR + ++ + S + +P TP
Sbjct: 996 GDLLAKSQTGDVSPKAQQPSEVTLKSHPLDLSPNVQSRDAIQKQASEDSNDLTPTLPETP 1055
Query: 271 SP 272
P
Sbjct: 1056 VP 1057
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 58.5 bits (140), Expect = 1e-08
Identities = 81/358 (22%), Positives = 129/358 (36%), Gaps = 70/358 (19%)
Query: 166 PRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPV--RPPVVP-------NDYVPSPTRNMA 216
P T PP S + K +LG P PV P+V +D +P+P+ N+A
Sbjct: 163 PVTVPPRLAGASQAKAYK-SLGEGPPANPPVPVLQSKPLVDIDLISFDDDVLPTPSGNLA 221
Query: 217 PSQ-------------QSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGV 263
QSP + T+S+ SG R+ + E++ G G
Sbjct: 222 EESVGSEMVLGLHEDPQSPPPLPAEKPIGNTFSTV--SGKLSNVERTRNLESNHPGQTGG 279
Query: 264 PIAVPTPSPPSVFPGH--PVQFYSMNRPASRHTPPTIGGS------LPYRRPPSITSQTS 315
+ VP PP G P Q P R PP + + LP+ R S
Sbjct: 280 FVRVPPRLPPRPVNGKTIPTQQPPTKVPPERPPPPKLSATRRSNKKLPFNRSSSDMDLQK 339
Query: 316 LQNQMNGG-------PFYSQNPVSLAPPPPS-----------ILQVTPQLPLMGFVARVQ 357
Q+ + G F +Q+PV P P +L + Q +
Sbjct: 340 KQSNLATGLSKAKSQVFKNQDPVLPPRPKPGHPLYSKYMRGDVLVMLKQTENNYLECQKG 399
Query: 358 ENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEK 417
E+ + P+ + P P ++ V+ P+A
Sbjct: 400 EDTGRVHLSQMKIITPLDEHLRSRPNDPSHAQKP----VDSGAPHA-------------- 441
Query: 418 VVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE 475
V ++D+ ++ D+L+ G I+Y+++K D WY G G+FP NYV+ I+ E
Sbjct: 442 -VVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVIIDIPE 498
Score = 54.3 bits (129), Expect = 2e-07
Identities = 23/52 (44%), Positives = 34/52 (65%)
Query: 417 KVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
K A+YD+ + EDELSF+ G II ++ DD W G + G +G+FP NY++
Sbjct: 675 KAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQ 726
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Query: 384 PPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVA-----IYDYTKDKEDELSFQEGA 438
P EDY A V+ P + S + + A ++ +T + D+LSF+ G
Sbjct: 568 PVEDYPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGD 627
Query: 439 IIYVIKKNDDGWYEGVMNGVTGLFPGNYV 467
I ++++ D W G + G+FP +V
Sbjct: 628 RIQILERLDSDWCRGRLQDREGIFPAVFV 656
>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/53 (45%), Positives = 36/53 (67%)
Query: 418 VVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
V A +++ + EDELSF +G +I+V + + GW+EG +NG TG FP NYV +
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 30.8 bits (68), Expect = 2.8
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 21/152 (13%)
Query: 260 SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLP-YRRPPSITSQTSLQN 318
SVG P P P P HPV P+S+H P Y P + +
Sbjct: 403 SVGNPTIKPHSVPSHTLPSHPV------TPSSKHADSKPAPLTPAYHTLPHPSHHGTPHT 456
Query: 319 QMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDES 378
+N GP P P S+ + P PL A + D P +++ +
Sbjct: 457 TINWGPLEPPK----TPKPWSLSCLRPAPPLRPSAALCYK--EDLSKSPKTMKKLLPKRK 510
Query: 379 PPPPPPPEDYE--------EEEAAVVEYSDPY 402
P P E++ EE+A +++ + Y
Sbjct: 511 PERKPSDEEFASRKSTAALEEDAQILKVIEAY 542
>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
sapiens]
Length = 753
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/53 (45%), Positives = 36/53 (67%)
Query: 418 VVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
V A +++ + EDELSF +G +I+V + + GW+EG +NG TG FP NYV +
Sbjct: 139 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREV 191
Score = 30.8 bits (68), Expect = 2.8
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 21/152 (13%)
Query: 260 SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLP-YRRPPSITSQTSLQN 318
SVG P P P P HPV P+S+H P Y P + +
Sbjct: 531 SVGNPTIKPHSVPSHTLPSHPV------TPSSKHADSKPAPLTPAYHTLPHPSHHGTPHT 584
Query: 319 QMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDES 378
+N GP P P S+ + P PL A + D P +++ +
Sbjct: 585 TINWGPLEPPK----TPKPWSLSCLRPAPPLRPSAALCYK--EDLSKSPKTMKKLLPKRK 638
Query: 379 PPPPPPPEDYE--------EEEAAVVEYSDPY 402
P P E++ EE+A +++ + Y
Sbjct: 639 PERKPSDEEFASRKSTAALEEDAQILKVIEAY 670
>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
sapiens]
Length = 803
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/53 (45%), Positives = 36/53 (67%)
Query: 418 VVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
V A +++ + EDELSF +G +I+V + + GW+EG +NG TG FP NYV +
Sbjct: 189 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREV 241
Score = 30.8 bits (68), Expect = 2.8
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 21/152 (13%)
Query: 260 SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLP-YRRPPSITSQTSLQN 318
SVG P P P P HPV P+S+H P Y P + +
Sbjct: 581 SVGNPTIKPHSVPSHTLPSHPV------TPSSKHADSKPAPLTPAYHTLPHPSHHGTPHT 634
Query: 319 QMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDES 378
+N GP P P S+ + P PL A + D P +++ +
Sbjct: 635 TINWGPLEPPK----TPKPWSLSCLRPAPPLRPSAALCYK--EDLSKSPKTMKKLLPKRK 688
Query: 379 PPPPPPPEDYE--------EEEAAVVEYSDPY 402
P P E++ EE+A +++ + Y
Sbjct: 689 PERKPSDEEFASRKSTAALEEDAQILKVIEAY 720
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/53 (45%), Positives = 36/53 (67%)
Query: 418 VVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
V A +++ + EDELSF +G +I+V + + GW+EG +NG TG FP NYV +
Sbjct: 168 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREV 220
Score = 30.8 bits (68), Expect = 2.8
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 21/152 (13%)
Query: 260 SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLP-YRRPPSITSQTSLQN 318
SVG P P P P HPV P+S+H P Y P + +
Sbjct: 560 SVGNPTIKPHSVPSHTLPSHPV------TPSSKHADSKPAPLTPAYHTLPHPSHHGTPHT 613
Query: 319 QMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDES 378
+N GP P P S+ + P PL A + D P +++ +
Sbjct: 614 TINWGPLEPPK----TPKPWSLSCLRPAPPLRPSAALCYK--EDLSKSPKTMKKLLPKRK 667
Query: 379 PPPPPPPEDYE--------EEEAAVVEYSDPY 402
P P E++ EE+A +++ + Y
Sbjct: 668 PERKPSDEEFASRKSTAALEEDAQILKVIEAY 699
>gi|4505573 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/53 (45%), Positives = 36/53 (67%)
Query: 418 VVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 470
V A +++ + EDELSF +G +I+V + + GW+EG +NG TG FP NYV +
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 30.8 bits (68), Expect = 2.8
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 21/152 (13%)
Query: 260 SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLP-YRRPPSITSQTSLQN 318
SVG P P P P HPV P+S+H P Y P + +
Sbjct: 403 SVGNPTIKPHSVPSHTLPSHPV------TPSSKHADSKPAPLTPAYHTLPHPSHHGTPHT 456
Query: 319 QMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDES 378
+N GP P P S+ + P PL A + D P +++ +
Sbjct: 457 TINWGPLEPPK----TPKPWSLSCLRPAPPLRPSAALCYK--EDLSKSPKTMKKLLPKRK 510
Query: 379 PPPPPPPEDYE--------EEEAAVVEYSDPY 402
P P E++ EE+A +++ + Y
Sbjct: 511 PERKPSDEEFASRKSTAALEEDAQILKVIEAY 542
>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
Length = 261
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 13/106 (12%)
Query: 369 PVEEPVFDESPPPPPPPEDYE--EEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTK 426
P PV+ + P P + Y +E AA V AP ++ A+YDY+
Sbjct: 165 PTSAPVYQQ-PQQQPVAQSYGGYKEPAAPVSIQRS--------APGGGGKRYRAVYDYSA 215
Query: 427 DKEDELSFQEGAIIYVIKKNDDGWYEGVM--NGVTGLFPGNYVESI 470
EDE+SFQ+G I +++ DDGW G + G TG+ P NYVE+I
Sbjct: 216 ADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,434,041
Number of Sequences: 37866
Number of extensions: 1643078
Number of successful extensions: 23857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 514
Number of HSP's successfully gapped in prelim test: 1092
Number of HSP's that attempted gapping in prelim test: 11283
Number of HSP's gapped (non-prelim): 7597
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.