Guide to the Human Genome
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Search of human proteins with 109689720

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109689720 acyl-Coenzyme A binding domain containing 5
isoform 2 [Homo sapiens]
         (490 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109689720 acyl-Coenzyme A binding domain containing 5 isoform...   995   0.0  
gi|203098629 acyl-Coenzyme A binding domain containing 5 isoform...   995   0.0  
gi|209364592 acyl-Coenzyme A binding domain containing 4 isoform...   150   3e-36
gi|13376029 acyl-Coenzyme A binding domain containing 4 isoform ...   150   3e-36
gi|209364600 acyl-Coenzyme A binding domain containing 4 isoform...   149   6e-36
gi|209364594 acyl-Coenzyme A binding domain containing 4 isoform...   149   6e-36
gi|209364589 acyl-Coenzyme A binding domain containing 4 isoform...   149   6e-36
gi|45643119 peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 [Hom...    79   9e-15
gi|10140853 diazepam binding inhibitor isoform 1 [Homo sapiens]        67   3e-11
gi|120433590 diazepam binding inhibitor isoform 3 [Homo sapiens]       66   6e-11
gi|120433593 diazepam binding inhibitor isoform 2 [Homo sapiens]       65   1e-10
gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo sa...    59   8e-09
gi|89886362 acyl-Coenzyme A binding domain containing 7 [Homo sa...    50   4e-06
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa...    49   1e-05
gi|55956899 keratin 9 [Homo sapiens]                                   44   4e-04
gi|57864582 hornerin [Homo sapiens]                                    43   6e-04
gi|55953076 connexin 50 [Homo sapiens]                                 41   0.003
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    40   0.006
gi|169208924 PREDICTED: similar to hCG1652800 [Homo sapiens]           38   0.024
gi|89039114 PREDICTED: similar to hCG1652800 [Homo sapiens]            38   0.024
gi|89038414 PREDICTED: similar to diazepam binding inhibitor [Ho...    38   0.024
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     37   0.041
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     37   0.041
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    37   0.041
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    37   0.041
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    37   0.041
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    37   0.041
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    37   0.041
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    37   0.053
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    36   0.070

>gi|109689720 acyl-Coenzyme A binding domain containing 5 isoform 2
           [Homo sapiens]
          Length = 490

 Score =  995 bits (2573), Expect = 0.0
 Identities = 490/490 (100%), Positives = 490/490 (100%)

Query: 1   MADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDP 60
           MADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDP
Sbjct: 1   MADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDP 60

Query: 61  IGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKS 120
           IGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKS
Sbjct: 61  IGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKS 120

Query: 121 GRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKK 180
           GRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKK
Sbjct: 121 GRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKK 180

Query: 181 SADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIH 240
           SADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIH
Sbjct: 181 SADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIH 240

Query: 241 QDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQP 300
           QDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQP
Sbjct: 241 QDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQP 300

Query: 301 MENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFS 360
           MENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFS
Sbjct: 301 MENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFS 360

Query: 361 NVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVL 420
           NVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVL
Sbjct: 361 NVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVL 420

Query: 421 QRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYL 480
           QRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYL
Sbjct: 421 QRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYL 480

Query: 481 YYQRRRRKLN 490
           YYQRRRRKLN
Sbjct: 481 YYQRRRRKLN 490


>gi|203098629 acyl-Coenzyme A binding domain containing 5 isoform 1
           [Homo sapiens]
          Length = 525

 Score =  995 bits (2573), Expect = 0.0
 Identities = 490/490 (100%), Positives = 490/490 (100%)

Query: 1   MADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDP 60
           MADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDP
Sbjct: 36  MADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDP 95

Query: 61  IGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKS 120
           IGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKS
Sbjct: 96  IGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKS 155

Query: 121 GRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKK 180
           GRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKK
Sbjct: 156 GRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKK 215

Query: 181 SADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIH 240
           SADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIH
Sbjct: 216 SADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIH 275

Query: 241 QDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQP 300
           QDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQP
Sbjct: 276 QDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQP 335

Query: 301 MENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFS 360
           MENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFS
Sbjct: 336 MENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFS 395

Query: 361 NVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVL 420
           NVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVL
Sbjct: 396 NVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQNVL 455

Query: 421 QRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYL 480
           QRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYL
Sbjct: 456 QRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSWWPFEMSPGVLTFAIIWPFIAQWLVYL 515

Query: 481 YYQRRRRKLN 490
           YYQRRRRKLN
Sbjct: 516 YYQRRRRKLN 525


>gi|209364592 acyl-Coenzyme A binding domain containing 4 isoform 2
           [Homo sapiens]
          Length = 305

 Score =  150 bits (378), Expect = 3e-36
 Identities = 85/207 (41%), Positives = 120/207 (57%), Gaps = 20/207 (9%)

Query: 9   ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDA 68
           + +F+AAV VIQ+LPKNGS++P+ E ML+FYS+YKQAT GPC + RPGFWDPIGRYKWDA
Sbjct: 13  QKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMGPCLVPRPGFWDPIGRYKWDA 72

Query: 69  WSSLGDMTKEEAMIAYVEEMK----KIIETMPMTEKVEELLRVIGPFYEIVEDKKSGRSS 124
           W+SLG M++EEAM AY+ EMK    K+I+T+P+ E  E++     P Y+++ D      +
Sbjct: 73  WNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPDMPRPPET 132

Query: 125 DITSDLGNVLTSTPNAKTVNGKAESSDSGAESE-----EEEAQEEVKGAEQSDNDKKMMK 179
            +    G         + VNG     D GA SE     +E A    +     D D ++  
Sbjct: 133 FLRRVTG------WKEQVVNG-----DVGAVSEPPCLPKEPAPPSPESHSPRDLDSEVFC 181

Query: 180 KSADHKNLEVIVTNGYDKDGFVQDIQN 206
            S +    E++ T      G  +D +N
Sbjct: 182 DSLEQLEPELVWTEQRAASGGKRDPRN 208



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 21/81 (25%)

Query: 412 LQEDMQNVLQRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSW------WPFEMSPGVLT 465
           LQE MQ V  R+Q LE++               P+P  QRP        WP  +    L 
Sbjct: 240 LQESMQEVQARVQSLESM---------------PRPPEQRPQPRPSARPWPLGLPGPALL 284

Query: 466 FAIIWPFIAQWLVYLYYQRRR 486
           F ++WPF+ QWL  ++  ++R
Sbjct: 285 FFLLWPFVVQWLFRMFRTQKR 305


>gi|13376029 acyl-Coenzyme A binding domain containing 4 isoform 2
           [Homo sapiens]
          Length = 305

 Score =  150 bits (378), Expect = 3e-36
 Identities = 85/207 (41%), Positives = 120/207 (57%), Gaps = 20/207 (9%)

Query: 9   ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDA 68
           + +F+AAV VIQ+LPKNGS++P+ E ML+FYS+YKQAT GPC + RPGFWDPIGRYKWDA
Sbjct: 13  QKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMGPCLVPRPGFWDPIGRYKWDA 72

Query: 69  WSSLGDMTKEEAMIAYVEEMK----KIIETMPMTEKVEELLRVIGPFYEIVEDKKSGRSS 124
           W+SLG M++EEAM AY+ EMK    K+I+T+P+ E  E++     P Y+++ D      +
Sbjct: 73  WNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPDMPRPPET 132

Query: 125 DITSDLGNVLTSTPNAKTVNGKAESSDSGAESE-----EEEAQEEVKGAEQSDNDKKMMK 179
            +    G         + VNG     D GA SE     +E A    +     D D ++  
Sbjct: 133 FLRRVTG------WKEQVVNG-----DVGAVSEPPCLPKEPAPPSPESHSPRDLDSEVFC 181

Query: 180 KSADHKNLEVIVTNGYDKDGFVQDIQN 206
            S +    E++ T      G  +D +N
Sbjct: 182 DSLEQLEPELVWTEQRAASGGKRDPRN 208



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 21/81 (25%)

Query: 412 LQEDMQNVLQRLQKLETLTALQAKSSTSTLQTAPQPTSQRPSW------WPFEMSPGVLT 465
           LQE MQ V  R+Q LE++               P+P  QRP        WP  +    L 
Sbjct: 240 LQESMQEVQARVQSLESM---------------PRPPEQRPQPRPSARPWPLGLPGPALL 284

Query: 466 FAIIWPFIAQWLVYLYYQRRR 486
           F ++WPF+ QWL  ++  ++R
Sbjct: 285 FFLLWPFVVQWLFRMFRTQKR 305


>gi|209364600 acyl-Coenzyme A binding domain containing 4 isoform 3
           [Homo sapiens]
          Length = 268

 Score =  149 bits (376), Expect = 6e-36
 Identities = 66/113 (58%), Positives = 89/113 (78%), Gaps = 4/113 (3%)

Query: 9   ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDA 68
           + +F+AAV VIQ+LPKNGS++P+ E ML+FYS+YKQAT GPC + RPGFWDPIGRYKWDA
Sbjct: 13  QKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMGPCLVPRPGFWDPIGRYKWDA 72

Query: 69  WSSLGDMTKEEAMIAYVEEMK----KIIETMPMTEKVEELLRVIGPFYEIVED 117
           W+SLG M++EEAM AY+ EMK    K+I+T+P+ E  E++     P Y+++ D
Sbjct: 73  WNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPD 125



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 256 HLTSDSDSEVYCDSMEQFGQEES 278
           H   D DSEV+CDS+EQ   E S
Sbjct: 170 HSPRDLDSEVFCDSLEQLEPELS 192


>gi|209364594 acyl-Coenzyme A binding domain containing 4 isoform 1
           [Homo sapiens]
          Length = 341

 Score =  149 bits (376), Expect = 6e-36
 Identities = 66/113 (58%), Positives = 89/113 (78%), Gaps = 4/113 (3%)

Query: 9   ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDA 68
           + +F+AAV VIQ+LPKNGS++P+ E ML+FYS+YKQAT GPC + RPGFWDPIGRYKWDA
Sbjct: 13  QKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMGPCLVPRPGFWDPIGRYKWDA 72

Query: 69  WSSLGDMTKEEAMIAYVEEMK----KIIETMPMTEKVEELLRVIGPFYEIVED 117
           W+SLG M++EEAM AY+ EMK    K+I+T+P+ E  E++     P Y+++ D
Sbjct: 73  WNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPD 125


>gi|209364589 acyl-Coenzyme A binding domain containing 4 isoform 1
           [Homo sapiens]
          Length = 341

 Score =  149 bits (376), Expect = 6e-36
 Identities = 66/113 (58%), Positives = 89/113 (78%), Gaps = 4/113 (3%)

Query: 9   ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDA 68
           + +F+AAV VIQ+LPKNGS++P+ E ML+FYS+YKQAT GPC + RPGFWDPIGRYKWDA
Sbjct: 13  QKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMGPCLVPRPGFWDPIGRYKWDA 72

Query: 69  WSSLGDMTKEEAMIAYVEEMK----KIIETMPMTEKVEELLRVIGPFYEIVED 117
           W+SLG M++EEAM AY+ EMK    K+I+T+P+ E  E++     P Y+++ D
Sbjct: 73  WNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPD 125


>gi|45643119 peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 [Homo
           sapiens]
          Length = 364

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 37/91 (40%), Positives = 58/91 (63%), Gaps = 4/91 (4%)

Query: 12  FEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSS 71
           FE ++  ++ L K+    P NE+ LK Y+ YKQATEGPC + +PG +D I + KWDAW++
Sbjct: 13  FENSMNQVKLLKKD----PGNEVKLKLYALYKQATEGPCNMPKPGVFDLINKAKWDAWNA 68

Query: 72  LGDMTKEEAMIAYVEEMKKIIETMPMTEKVE 102
           LG + KE A   YV+ +  +  ++  + +VE
Sbjct: 69  LGSLPKEAARQNYVDLVSSLSPSLESSSQVE 99


>gi|10140853 diazepam binding inhibitor isoform 1 [Homo sapiens]
          Length = 104

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 38/85 (44%), Positives = 49/85 (57%), Gaps = 7/85 (8%)

Query: 9   ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDA 68
           E  FE A + ++ L      +P++E ML  Y  YKQAT G     RPG  D  G+ KWDA
Sbjct: 20  EAEFEKAAEEVRHLKT----KPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDA 75

Query: 69  WSSLGDMTKEEAMIAY---VEEMKK 90
           W+ L   +KE+AM AY   VEE+KK
Sbjct: 76  WNELKGTSKEDAMKAYINKVEELKK 100


>gi|120433590 diazepam binding inhibitor isoform 3 [Homo sapiens]
          Length = 87

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 37/85 (43%), Positives = 49/85 (57%), Gaps = 7/85 (8%)

Query: 9  ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDA 68
          +  FE A + ++ L      +P++E ML  Y  YKQAT G     RPG  D  G+ KWDA
Sbjct: 3  QAEFEKAAEEVRHLKT----KPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDA 58

Query: 69 WSSLGDMTKEEAMIAY---VEEMKK 90
          W+ L   +KE+AM AY   VEE+KK
Sbjct: 59 WNELKGTSKEDAMKAYINKVEELKK 83


>gi|120433593 diazepam binding inhibitor isoform 2 [Homo sapiens]
          Length = 88

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 7/82 (8%)

Query: 12 FEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSS 71
          FE A + ++ L      +P++E ML  Y  YKQAT G     RPG  D  G+ KWDAW+ 
Sbjct: 7  FEKAAEEVRHLKT----KPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDAWNE 62

Query: 72 LGDMTKEEAMIAY---VEEMKK 90
          L   +KE+AM AY   VEE+KK
Sbjct: 63 LKGTSKEDAMKAYINKVEELKK 84


>gi|14150169 acyl-coenzyme A binding domain containing 6 [Homo
           sapiens]
          Length = 282

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 4/80 (5%)

Query: 12  FEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSS 71
           FE A   +Q L +  S     E +L  Y+ YKQ   G C   +P F+D  G+ KW+AW +
Sbjct: 46  FEKAAAHLQGLIQVAS----REQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKA 101

Query: 72  LGDMTKEEAMIAYVEEMKKI 91
           LGD +  +AM  Y+  +KK+
Sbjct: 102 LGDSSPSQAMQEYIAVVKKL 121


>gi|89886362 acyl-Coenzyme A binding domain containing 7 [Homo
          sapiens]
          Length = 88

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 22/65 (33%), Positives = 38/65 (58%)

Query: 29 QPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEM 88
          +P +  + + Y  YKQA  G   ++ PG  D  G+ KW+AW+    ++ E+A  AY+ + 
Sbjct: 20 RPDDGELKELYGLYKQAIVGDINIACPGMLDLKGKAKWEAWNLKKGLSTEDATSAYISKA 79

Query: 89 KKIIE 93
          K++IE
Sbjct: 80 KELIE 84


>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
           sapiens]
          Length = 528

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 26/83 (31%), Positives = 46/83 (55%), Gaps = 6/83 (7%)

Query: 27  SFQPTNEMMLKFYSFYKQATEGPCK---LSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIA 83
           +F PT E  LK  + +KQ   GP         GF+D +G  +   W++LG+M+KE+AM+ 
Sbjct: 101 AFHPTYEEKLKLVALHKQVLMGPYNPDTCPEVGFFDVLGNDRRREWAALGNMSKEDAMVE 160

Query: 84  YVEEMKK---IIETMPMTEKVEE 103
           +V+ + +   +  T   + K+E+
Sbjct: 161 FVKLLNRCCHLFSTYVASHKIEK 183


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 64/303 (21%), Positives = 124/303 (40%), Gaps = 46/303 (15%)

Query: 112 YEIVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQS 171
           +E+ ++ + G  +DI   L  VL +    K          S  E + E  QEE+   +++
Sbjct: 243 FEMEQNLRQGVDADING-LRQVLDNLTMEK----------SDLEMQYETLQEELMALKKN 291

Query: 172 DNDK--KMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTE-----EVKP 224
             ++  ++  +++   N+E+ V  G D    + D++ +     + N +  E     ++  
Sbjct: 292 HKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQ 351

Query: 225 IDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTS 284
           I+  +  +G+              ++VT ++H   + + E+     ++   E+SL+  T 
Sbjct: 352 IEHEVSSSGQEV--------QSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLED-TK 402

Query: 285 NN--GPFQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKH----GGE 338
           N   G  Q      S+   + +  R++I+      ++     + +E + E  H    GG+
Sbjct: 403 NRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQ 462

Query: 339 DGRNNSGAPH--REKRGGETDEFSNVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRG 396
           +   +SGA       RGG    +     GRG R      G  G   G GG G  +G   G
Sbjct: 463 EDFESSGAGKIGLGGRGGSGGSY-----GRGSR------GGSGGSYGGGGSGGGYGGGSG 511

Query: 397 SRG 399
           SRG
Sbjct: 512 SRG 514


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 58/288 (20%), Positives = 109/288 (37%), Gaps = 26/288 (9%)

Query: 117 DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKK 176
           D+   +  D T  L  +         + GK     SG++  ++  Q + +  E    + K
Sbjct: 62  DRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENK 121

Query: 177 MMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIH-ASSSLNGRSTEEVKPIDENLGQTGKS 235
             + S  H +      +  + D + ++++  +   + S++ R + +     ++   +G+S
Sbjct: 122 RQESSFSHSS-----WSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQS 176

Query: 236 AVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGG 295
           +    Q+ +D H     G Q  +    S  Y       GQ  S D+  S +G    +   
Sbjct: 177 SSYGEQN-SDSHQSSGRG-QCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGF-SQ 233

Query: 296 HSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGE 355
           H S   ++SG+    Q   G+G+            G  +HG   G+++ G  HR    G 
Sbjct: 234 HKSSSGQSSGYS---QHGSGSGH----------SSGYGQHGSRSGQSSRGERHRSS-SGS 279

Query: 356 TDEFSNVRRGRGHRMQHLSEGTKGRQVGS---GGDGERWGSDRGSRGS 400
           +  +     G    + H  +G+  RQ  S    G G    S  G  GS
Sbjct: 280 SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGS 327



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 16/155 (10%)

Query: 255  QHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQ--- 311
            QH +S   S  +       GQ  S     +++G    + G H S   ++SG+        
Sbjct: 1065 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSG 1123

Query: 312  VPPGNGNIGNMQVVAVE------GKGEVKHGGEDGRN---NSGAPHREKRGGETDEFSNV 362
              PG+G  G+    +        G G     G+ G     +SG  H E   G++  +S  
Sbjct: 1124 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 1183

Query: 363  RRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGS 397
              G GH   +   G  G + G    GER GS  GS
Sbjct: 1184 GSGSGHSSGY---GQHGSRSGQSSRGERHGSSSGS 1215



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 16/155 (10%)

Query: 255  QHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQ--- 311
            QH +S   S  +       GQ  S     +++G    + G H S   ++SG+        
Sbjct: 2475 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSG 2533

Query: 312  VPPGNGNIGNMQVVAVE------GKGEVKHGGEDGRN---NSGAPHREKRGGETDEFSNV 362
              PG+G  G+    +        G G     G+ G     +SG  H E   G++  +S  
Sbjct: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 2593

Query: 363  RRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGS 397
              G GH   +   G  G + G    GER GS  GS
Sbjct: 2594 GSGSGHSSGY---GQHGSRSGQSSRGERHGSSSGS 2625



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 16/155 (10%)

Query: 255  QHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQ--- 311
            QH +S   S  +       GQ  S     +++G    + G H S   ++SG+        
Sbjct: 2005 QHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSG 2063

Query: 312  VPPGNGNIGNMQVVAVE------GKGEVKHGGEDGRN---NSGAPHREKRGGETDEFSNV 362
              PG+G  G+    +        G G     G+ G     +SG  H E   G++  +S  
Sbjct: 2064 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQH 2123

Query: 363  RRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGS 397
              G GH   +   G  G + G    GER GS  GS
Sbjct: 2124 GSGSGHSSGY---GQHGSRSGQSSRGERHGSSSGS 2155



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 39/155 (25%), Positives = 58/155 (37%), Gaps = 16/155 (10%)

Query: 255  QHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQ--- 311
            QH +S   S  +       GQ  S     +++G    + G H S   ++SG+        
Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSG 1593

Query: 312  VPPGNGNIGNMQVVAVE------GKGEVKHGGEDGRN---NSGAPHREKRGGETDEFSNV 362
              PG+G  G+    +        G G     G+ G     +SG  H E   G++  +S  
Sbjct: 1594 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 1653

Query: 363  RRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGS 397
              G GH   +   G  G + G    GER GS   S
Sbjct: 1654 GSGSGHSSGY---GQHGSRSGQSSRGERHGSSSRS 1685



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 38/156 (24%), Positives = 56/156 (35%), Gaps = 12/156 (7%)

Query: 255  QHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPP 314
            QH +    S  Y     + GQ    +   S++G    Y G H S   ++SG         
Sbjct: 2122 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY-GQHGSGSRQSSGHGRQGSGSG 2180

Query: 315  GNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGHR---MQ 371
             + + G     +       +HG   GR++S  P+ E R G +  F     G GH     Q
Sbjct: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPY-ESRSGHSSVFGQHESGSGHSSAYSQ 2239

Query: 372  H-------LSEGTKGRQVGSGGDGERWGSDRGSRGS 400
            H        S+G  G   G     ++ GS  G   S
Sbjct: 2240 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 36/158 (22%), Positives = 54/158 (34%), Gaps = 10/158 (6%)

Query: 252  TGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQ 311
            +G  H  S             F QE S    +S++G         SS   + SG  +   
Sbjct: 2242 SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPS 2301

Query: 312  VPPGNGNIGNMQVVAVEGKGEV------KHGGEDGRNNSGAPHREKRGGETDEFSNVRRG 365
                    G+       G G        +HG   G++ SG  H E    ++  ++    G
Sbjct: 2302 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS-SGFGHHESSSWQSSGYTQHGSG 2360

Query: 366  RGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNE 403
             GH   +   G++    G    GER GS  GS  S  +
Sbjct: 2361 SGHSSSYEQHGSRS---GQSSRGERHGSSSGSSSSYGQ 2395



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 65/298 (21%), Positives = 103/298 (34%), Gaps = 30/298 (10%)

Query: 117  DKKSGRSSDIT---SDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQ-EEVKGAEQSD 172
            + +SG+SS      S  G+  T   +  T    +     GA S +  +  +   G+ QS 
Sbjct: 2464 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 2523

Query: 173  NDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQT 232
               +    S           +G    G  Q      H S S  GRS+       ++    
Sbjct: 2524 GYGRQGSGSGQSPG------HGQRGSGSRQSPSYGRHGSGS--GRSSSS----GQHGSGL 2571

Query: 233  GKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYY 292
            G+S+   H + +       +  QH +    S  Y     + GQ    +   S++G   +Y
Sbjct: 2572 GESSGFGHHESSSGQSSSYS--QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHY 2629

Query: 293  LGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKR 352
             G H S   ++SG          + + G             +HG   GR++S  P+ E R
Sbjct: 2630 -GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY-ESR 2687

Query: 353  GGETDEFSNVRRGRGHR---MQH-------LSEGTKGRQVGSGGDGERWGSDRGSRGS 400
             G +  F     G GH     QH        S+G  G   G     ++ GS  G   S
Sbjct: 2688 LGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2745



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 35/158 (22%), Positives = 54/158 (34%), Gaps = 10/158 (6%)

Query: 252  TGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQ 311
            +G  H  S             F QE S    +S++G         SS   + SG  +   
Sbjct: 1772 SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPS 1831

Query: 312  VPPGNGNIGNMQVVAVEGKGEV------KHGGEDGRNNSGAPHREKRGGETDEFSNVRRG 365
                    G+       G G        +HG   G++ SG  H E    ++  ++    G
Sbjct: 1832 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS-SGFGHHESSSWQSSGYTQHGSG 1890

Query: 366  RGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNE 403
             GH   +   G++    G    GE+ GS  GS  S  +
Sbjct: 1891 SGHSSSYEQHGSRS---GQSSRGEQHGSSSGSSSSYGQ 1925



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 34/155 (21%), Positives = 57/155 (36%), Gaps = 9/155 (5%)

Query: 255 QHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPP 314
           +H +    S  Y       G+  S   + S +G     LG   S+  ++SG+ +      
Sbjct: 547 RHESGSRQSSSYGPHGYGSGRSSSRGPYESGSG-HSSGLGHQESRSGQSSGYGQHGSSSG 605

Query: 315 GNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPH-----REKRGGETDEFSNVRRGRGHR 369
            +   G     + +     +HG   G+++S   H     +  R G+    S     RG  
Sbjct: 606 HSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRG-- 663

Query: 370 MQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQ 404
            +H S+       G  G G  W S  G  GS++ Q
Sbjct: 664 -RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQ 697



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 64/298 (21%), Positives = 101/298 (33%), Gaps = 30/298 (10%)

Query: 117  DKKSGRSSDIT---SDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQ-EEVKGAEQSD 172
            + +SG+SS      S  G+  T   +  T    +     GA S +  +  +   G+ QS 
Sbjct: 1524 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1583

Query: 173  NDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQT 232
               +    S           +G    G  Q      H S S  GRS+       ++    
Sbjct: 1584 GYGRQGSGSGQSPG------HGQRGSGSRQSPSYGRHGSGS--GRSSSS----GQHGSGL 1631

Query: 233  GKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYY 292
            G+S+   H + +       +  QH +    S  Y     + GQ    +   S++     Y
Sbjct: 1632 GESSGFGHHESSSGQSSSYS--QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY 1689

Query: 293  LGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKR 352
             G H S   ++SG          + + G             +HG   GR++S  P+ E R
Sbjct: 1690 -GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY-ESR 1747

Query: 353  GGETDEFSNVRRGRGHR---MQH-------LSEGTKGRQVGSGGDGERWGSDRGSRGS 400
             G +  F     G GH     QH        S+G  G   G     ++ GS  G   S
Sbjct: 1748 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 46/196 (23%), Positives = 64/196 (32%), Gaps = 57/196 (29%)

Query: 252  TGIQHLTSDSDSEVYCD---------SMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPME 302
            +G  H +S   S  Y           S EQ G      S +  +G      G  SS    
Sbjct: 930  SGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSS---GSSSSYGQH 986

Query: 303  NSGFREDIQVPPGNGNIGNMQVVAVEGKGEV------KHGGEDGRNNSGAP--------- 347
             SG R+ +    G+G  G+       G G+       +HG   G+++S  P         
Sbjct: 987  GSGSRQSL----GHGQHGS-------GSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSS 1035

Query: 348  ----------------HREKRGGETDEFSNVRRGRGHRMQHLSEG-TKGRQVGSGGDGER 390
                            HRE R G++  +       GH   H   G T G+    G  G  
Sbjct: 1036 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGAS 1095

Query: 391  WG--SDRGSRGSLNEQ 404
             G  S  G  GS + Q
Sbjct: 1096 SGQSSSHGQHGSGSSQ 1111



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 37/144 (25%), Positives = 55/144 (38%), Gaps = 20/144 (13%)

Query: 274  GQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFRE----DIQVPP----GNGNIGNMQVV 325
            GQ  + D   S+ G    Y G   S   ++SG+        Q P     G+G+ G+    
Sbjct: 1318 GQSSTFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS-GHSSSY 1375

Query: 326  AVEGKGEV------KHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEGTKG 379
               G G        +HG   G++ SG  H E    ++   +    G GH   +   G++ 
Sbjct: 1376 GQHGSGSGWSSSSGRHGSGSGQS-SGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRS 1434

Query: 380  RQVGSGGDGERWGSDRGSRGSLNE 403
               G    GER GS  GS  S  +
Sbjct: 1435 ---GQSSRGERHGSSSGSSSSYGQ 1455



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 3/66 (4%)

Query: 342  NNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEG-TKGRQVGSGGDGERWG--SDRGSR 398
            ++SG  HRE R G++  +       GH   H   G T G+    G  G   G  S  G  
Sbjct: 1516 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 1575

Query: 399  GSLNEQ 404
            GS + Q
Sbjct: 1576 GSGSSQ 1581



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 3/66 (4%)

Query: 342  NNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEG-TKGRQVGSGGDGERWG--SDRGSR 398
            ++SG  HRE R G++  +       GH   H   G T G+    G  G   G  S  G  
Sbjct: 2456 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 2515

Query: 399  GSLNEQ 404
            GS + Q
Sbjct: 2516 GSGSSQ 2521



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 3/66 (4%)

Query: 342  NNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEGTKGRQ---VGSGGDGERWGSDRGSR 398
            ++SG  HRE R G++  +       GH   H   G+   Q    G  G      S  G  
Sbjct: 1986 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQH 2045

Query: 399  GSLNEQ 404
            GS + Q
Sbjct: 2046 GSGSSQ 2051



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 44/193 (22%), Positives = 68/193 (35%), Gaps = 26/193 (13%)

Query: 232 TGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQY 291
           +G S+   H + + +H    T  QH +    S  +     + GQ    +   S+ G    
Sbjct: 459 SGYSSGFGHHESSSEHSSGYT--QHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSS 516

Query: 292 YLGGHSSQPMENSGFREDIQVPPGNGNI-----GNMQVVAVEGKGEVKHGGEDGRNNSGA 346
           Y G H S   ++ G         G+G       G  +  + +      HG   GR++S  
Sbjct: 517 Y-GQHGSGSRQSLGHSRH---GSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG 572

Query: 347 P------------HREKRGGETDEFSNVRRGRGHRMQHLSEG-TKGRQVGSGGDGERWG- 392
           P            H+E R G++  +       GH   H   G T G+    G  G   G 
Sbjct: 573 PYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQ 632

Query: 393 -SDRGSRGSLNEQ 404
            S  G  GS + Q
Sbjct: 633 SSSHGQHGSGSSQ 645



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 36/147 (24%)

Query: 273  FGQEESLDSFTSNNGPF------QYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVA 326
            +GQ  S   ++S++G            G H S   ++SG+    Q   G+G+  + +   
Sbjct: 1845 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT---QHGSGSGHSSSYE--- 1898

Query: 327  VEGKGEVKHGGEDGRNNSGAPHREKRGGETD---EFSNVRRGRGH--------------R 369
                   +HG   G+++ G  H    G  +      S  R+  GH              R
Sbjct: 1899 -------QHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1951

Query: 370  MQHLSEGTKGRQVGSGGDGERWGSDRG 396
             +H S   +    G  G G  W S RG
Sbjct: 1952 GRHGSGSGQSSSYGPYGSGSGWSSSRG 1978



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 36/137 (26%), Positives = 53/137 (38%), Gaps = 12/137 (8%)

Query: 274  GQEESLDSFTSNNGPFQYYLGGHSS---QPMENSGFREDI-QVPPGNGNIGNM-QVVAVE 328
            GQ  S    +S+ GP++    GHSS   Q    SG      Q   G+G+  +  Q  +  
Sbjct: 1259 GQHGSGSGRSSSRGPYESR-SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317

Query: 329  GKGEV--KHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGH---RMQHLSEGTKGRQVG 383
            G+     + G   G+++S   HR     ++  +     G G    R +H S        G
Sbjct: 1318 GQSSTFDQEGSSTGQSSSYG-HRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG 1376

Query: 384  SGGDGERWGSDRGSRGS 400
              G G  W S  G  GS
Sbjct: 1377 QHGSGSGWSSSSGRHGS 1393


>gi|55953076 connexin 50 [Homo sapiens]
          Length = 433

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/144 (25%), Positives = 61/144 (42%), Gaps = 10/144 (6%)

Query: 85  VEEMKKIIETMPMTE--KVEELLRVIGPFYEIVEDKKSGRSSDITSDLGNVLTSTPN--A 140
           +EE K +    P+TE   VE       PF +  E   +G   D++      L S     A
Sbjct: 269 LEEEKIVSHYFPLTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGA 328

Query: 141 KTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSADHKNLEVIVTNGYDKDGF 200
           + V G+   ++ GAE E  E +EE +     + +K  + +       E + T G DK+G 
Sbjct: 329 QEVEGEGPPAEEGAEPEVGEKKEEAERLTTEEQEKVAVPEG------EKVETPGVDKEGE 382

Query: 201 VQDIQNDIHASSSLNGRSTEEVKP 224
            ++ Q++  +   L    T  + P
Sbjct: 383 KEEPQSEKVSKQGLPAEKTPSLCP 406


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 33/172 (19%), Positives = 66/172 (38%), Gaps = 1/172 (0%)

Query: 116  EDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDK 175
            +   S  SSD +    +  + + N+   +  ++SS+S   S+  ++ E    ++ SD+  
Sbjct: 840  DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899

Query: 176  KMMKKSADHKNLEVIVTNGYDKDGFVQDIQND-IHASSSLNGRSTEEVKPIDENLGQTGK 234
                 S+D  N      +    D       +D  ++S S N   + +      +   +  
Sbjct: 900  SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959

Query: 235  SAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNN 286
            S      D +D +  D +   + +  SDS    DS +      S DS  S++
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 36/170 (21%), Positives = 60/170 (35%), Gaps = 1/170 (0%)

Query: 117 DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKK 176
           D  +   S  +SD  +   S+ N+   N  + SSDS   S   ++      ++ SD+   
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSS-NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818

Query: 177 MMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSA 236
               S+D  N      +    D       +D   S S N   +       ++   +  S 
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878

Query: 237 VCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNN 286
                D N+      +     +SDSDS    +S +      S DS  S+N
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 38/170 (22%), Positives = 66/170 (38%), Gaps = 4/170 (2%)

Query: 117 DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKK 176
           D  S  SSD +SD  N   S+ ++ + N  ++SSDS   S   ++ +    ++ SD+   
Sbjct: 725 DSDSSNSSD-SSDSSNSSDSSDSSDSSNS-SDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782

Query: 177 MMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSA 236
               S D  N      +    D       +D   SS  +  ++ +     ++   +  S 
Sbjct: 783 --SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840

Query: 237 VCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNN 286
                D +D    D +     ++ SDS    DS       +S DS  S+N
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 64/296 (21%), Positives = 119/296 (40%), Gaps = 40/296 (13%)

Query: 72  LGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELL----RVIGPFYEI---VEDKKSG-RS 123
           +GD    E +    E+  ++  +   T+  +E++    R  G   EI   +  K++G + 
Sbjct: 167 VGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKE 226

Query: 124 SDITSDLGNV--LTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDK----KM 177
           +++T   G    L ++  + + NG  E  D G+  +E+E  E   G + S+N K    + 
Sbjct: 227 AEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDE--EAGNGKDSSNNSKGQEGQD 284

Query: 178 MKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAV 237
             K  DH +   I  N   K+ +  + + D H  + ++G  T           ++ +++ 
Sbjct: 285 HGKEDDHDS--SIGQNSDSKEYYDPEGKEDPH--NEVDGDKT----------SKSEENSA 330

Query: 238 CIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLG--- 294
            I +D     +ED   + H  S           E     +S D      GP         
Sbjct: 331 GIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITK 390

Query: 295 --GHSSQPMENSGFREDIQVPPGNGNIGNM-QVVAVEGKGEVKH-GGEDGRNNSGA 346
             G  ++  E+ G    I    G GN+    +VV +EG G+    G + G +N+G+
Sbjct: 391 EVGKGNEGKEDKGQHGMIL---GKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGS 443



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 39/194 (20%), Positives = 72/194 (37%), Gaps = 9/194 (4%)

Query: 117 DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKK 176
           D  +  +S  +SD  +   S+ ++ + N    SSDS   S+   + E    ++ SD+D  
Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSN----SSDSSDSSDSSNSSESSDSSDSSDSDSS 713

Query: 177 MMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSA 236
               S++  + +   +N  D      D  N   +S S +  ++ +     ++   +  S 
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDS----SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769

Query: 237 VCIHQDIND-DHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGG 295
                D +D  +  D     + +  SDS    DS       +S DS  S++         
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829

Query: 296 HSSQPMENSGFRED 309
             S    NS    D
Sbjct: 830 SDSSDSSNSSDSSD 843



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 45/214 (21%), Positives = 75/214 (35%), Gaps = 16/214 (7%)

Query: 116  EDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSD-ND 174
            +   S  SSD +    +  + + N+   +  ++SSDS   S+  ++ +    +  SD +D
Sbjct: 1071 DSSDSSDSSDSSESSDS--SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128

Query: 175  KKMMKKSADHKNLEVIVTNGYDKDGF----------VQDIQNDIHASSSLNGRSTEEVKP 224
                  S+D  N      +    D              D  +   +S S N   + +   
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188

Query: 225  IDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTS 284
              ++   +  S      D +D    D +     +  SDS    DS E     +S DS  S
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDS--SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246

Query: 285  NNGPFQYYLGGHSSQPMENSGFREDIQVPPGNGN 318
            +N          SS    +S    D Q   GNGN
Sbjct: 1247 SNSS-DSSDSSDSSDSTSDSNDESDSQSKSGNGN 1279



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 41/175 (23%), Positives = 71/175 (40%), Gaps = 15/175 (8%)

Query: 120 SGRSSDITSDLGNVLTSTPNAKTVNGK----AESSDSGAESEEEEAQEEVKGAEQSD-ND 174
           S  SSD +SD  N   S+ ++ + +G     +  SDS   S+  ++ +    ++ SD +D
Sbjct: 826 SSNSSD-SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 175 KKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGK 234
                 S+D  +     +N  D D    D  N   +S S N   + E     +N   +  
Sbjct: 885 SNESSNSSDSSD----SSNSSDSDS--SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938

Query: 235 SAVCIHQDIND-DHVEDVTGIQHLTSDSDS--EVYCDSMEQFGQEESLDSFTSNN 286
           S      D +D  +  D +     ++ SDS      DS +     +S DS  S++
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 34/167 (20%), Positives = 62/167 (37%), Gaps = 5/167 (2%)

Query: 117 DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQ---EEVKGAEQSDN 173
           D KS +  D  S   +      N+++ N  +   D+   S+E +      + KGAE  D+
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDS 515

Query: 174 DKKMMKKSADHKNLEVIVTNGYDK--DGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQ 231
           D      ++D         +  DK   G  +   +D  +S S N   + +    D +   
Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575

Query: 232 TGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEES 278
           +   +     D +D    D +   + +  SDS    DS +     +S
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 22/170 (12%)

Query: 117 DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKK 176
           D  S  SSD  S      + + N+   +  ++SSDS   S+  +++ +   +E   +D  
Sbjct: 584 DSDSSDSSDSDS------SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637

Query: 177 MMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSA 236
               S+D        +N  D      D  +   +S+S N   + +     ++   +  S 
Sbjct: 638 SKSDSSD--------SNSSDSS----DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 237 VCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNN 286
                D +D      +     +SDSDS    DS        S DS +SN+
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS----SNSNSSDSDSSNS 731



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 36/167 (21%), Positives = 68/167 (40%), Gaps = 10/167 (5%)

Query: 120 SGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMK 179
           SG+    +SD  +  +S  +  + +  ++SSDS + S+ + +  +   ++ SD+D     
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSD--SSDSSDSDSSDSS 599

Query: 180 KSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCI 239
            S+D  +      +    D    D ++D   S S +  S  +    D N   +  ++   
Sbjct: 600 NSSDSSDSSDSSDSSDSSDS--SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS--- 654

Query: 240 HQDINDDHVEDVTGIQHLTSD-SDSEVYCDSMEQFGQEESLDSFTSN 285
             D +D      +     +SD SDS    DS       +S DS  S+
Sbjct: 655 --DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS 699



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 32/172 (18%), Positives = 62/172 (36%), Gaps = 3/172 (1%)

Query: 116 EDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDK 175
           +   S  SSD +    +   S  ++   + K++SSDS +    + +         + +D 
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668

Query: 176 KMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKS 235
                S+D  +      +    D    D  N   +S S +   ++     D +   +  S
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDS--SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726

Query: 236 AVCIHQDIND-DHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNN 286
                 D +D  +  D +     ++ SDS    DS       +S DS  S++
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 32/168 (19%), Positives = 62/168 (36%), Gaps = 8/168 (4%)

Query: 120  SGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKM-M 178
            S  SSD +    +  + + N+   +  ++SSDS   S+   + +    ++ SD+      
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 179  KKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVC 238
              S+D  N      +    D    D  +   +S S N   + +     ++   +  S   
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS--- 1076

Query: 239  IHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNN 286
                 +     D +   + +  SDS    DS +     +S DS  S+N
Sbjct: 1077 --DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 37/174 (21%), Positives = 63/174 (36%), Gaps = 4/174 (2%)

Query: 117  DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSD-NDK 175
            D  +   S  +SD  +   S+ N+   +  +ESSDS   S+  ++ +    ++ SD +D 
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSS-NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 176  KMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHAS--SSLNGRSTEEVKPIDENLGQTG 233
                 S+D  +      +    D       +D   S  SS +  S++     D N     
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237

Query: 234  KSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNG 287
              +       N     D +     TSDS+ E    S    G     DS + + G
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 35/189 (18%), Positives = 66/189 (34%), Gaps = 21/189 (11%)

Query: 117 DKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKK 176
           D     SSD  S   +   S+ +  + +  ++SSDS   S+  ++ +    ++ SD+   
Sbjct: 565 DSSDSDSSDSNSSSDS--DSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622

Query: 177 MMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSA 236
               S    +     +     D    D  ++  +S S N  ++ +     ++   +  S 
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682

Query: 237 VCIHQDIND-------------------DHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEE 277
                D +D                   D  +        +SDSDS    DS +     +
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742

Query: 278 SLDSFTSNN 286
           S DS  S+N
Sbjct: 743 SSDSSDSSN 751



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 38/200 (19%), Positives = 68/200 (34%), Gaps = 6/200 (3%)

Query: 116 EDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDS----GAESEEEEAQEEVKGAEQS 171
           +   S  SSD +    +  +S  +  + +  ++SSDS     ++S+   + +    +  S
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 172 D-NDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLG 230
           D +D      S+D  +      +    D       +D   SS  N  S         N  
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801

Query: 231 QTGKSA-VCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPF 289
            +  S+      D +D    + +   + +  SDS    DS +     +  DS +SN    
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861

Query: 290 QYYLGGHSSQPMENSGFRED 309
                   S    NS    D
Sbjct: 862 SNSSDSSDSSDSSNSSDSSD 881


>gi|169208924 PREDICTED: similar to hCG1652800 [Homo sapiens]
          Length = 88

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 17/65 (26%), Positives = 36/65 (55%)

Query: 29 QPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEM 88
          +P +E + + Y  YKQA  G   +      +  G+ KW+A +    +++E+ M A++ + 
Sbjct: 20 RPDDEELKELYGLYKQAVIGNINIECSEMLELKGKAKWEAQNPQKGLSEEDMMRAFISKA 79

Query: 89 KKIIE 93
          +++IE
Sbjct: 80 EELIE 84


>gi|89039114 PREDICTED: similar to hCG1652800 [Homo sapiens]
          Length = 88

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 17/65 (26%), Positives = 36/65 (55%)

Query: 29 QPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEM 88
          +P +E + + Y  YKQA  G   +      +  G+ KW+A +    +++E+ M A++ + 
Sbjct: 20 RPDDEELKELYGLYKQAVIGNINIECSEMLELKGKAKWEAQNPQKGLSEEDMMRAFISKA 79

Query: 89 KKIIE 93
          +++IE
Sbjct: 80 EELIE 84


>gi|89038414 PREDICTED: similar to diazepam binding inhibitor
          [Homo sapiens]
          Length = 88

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 17/65 (26%), Positives = 36/65 (55%)

Query: 29 QPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEM 88
          +P +E + + Y  YKQA  G   +      +  G+ KW+A +    +++E+ M A++ + 
Sbjct: 20 RPDDEELKELYGLYKQAVIGNINIECSEMLELKGKAKWEAQNPQKGLSEEDMMRAFISKA 79

Query: 89 KKIIE 93
          +++IE
Sbjct: 80 EELIE 84


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 114 IVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDN 173
           + E+K   R  D+ SDL ++  S    KT + ++ S++SG+ SEEEE +EE +  E S +
Sbjct: 240 VKEEKMEER--DLLSDLQDI--SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 295

Query: 174 DKKMMKKSADHKNLEVIVTN 193
           ++   ++  + +  E   +N
Sbjct: 296 EESEEEEEEEEEEEEETGSN 315


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 114 IVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDN 173
           + E+K   R  D+ SDL ++  S    KT + ++ S++SG+ SEEEE +EE +  E S +
Sbjct: 250 VKEEKMEER--DLLSDLQDI--SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 305

Query: 174 DKKMMKKSADHKNLEVIVTN 193
           ++   ++  + +  E   +N
Sbjct: 306 EESEEEEEEEEEEEEETGSN 325


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 114 IVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDN 173
           + E+K   R  D+ SDL ++  S    KT + ++ S++SG+ SEEEE +EE +  E S +
Sbjct: 241 VKEEKMEER--DLLSDLQDI--SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 296

Query: 174 DKKMMKKSADHKNLEVIVTN 193
           ++   ++  + +  E   +N
Sbjct: 297 EESEEEEEEEEEEEEETGSN 316


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 114 IVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDN 173
           + E+K   R  D+ SDL ++  S    KT + ++ S++SG+ SEEEE +EE +  E S +
Sbjct: 250 VKEEKMEER--DLLSDLQDI--SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 305

Query: 174 DKKMMKKSADHKNLEVIVTN 193
           ++   ++  + +  E   +N
Sbjct: 306 EESEEEEEEEEEEEEETGSN 325


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 114 IVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDN 173
           + E+K   R  D+ SDL ++  S    KT + ++ S++SG+ SEEEE +EE +  E S +
Sbjct: 218 VKEEKMEER--DLLSDLQDI--SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 273

Query: 174 DKKMMKKSADHKNLEVIVTN 193
           ++   ++  + +  E   +N
Sbjct: 274 EESEEEEEEEEEEEEETGSN 293


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 114 IVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDN 173
           + E+K   R  D+ SDL ++  S    KT + ++ S++SG+ SEEEE +EE +  E S +
Sbjct: 207 VKEEKMEER--DLLSDLQDI--SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 262

Query: 174 DKKMMKKSADHKNLEVIVTN 193
           ++   ++  + +  E   +N
Sbjct: 263 EESEEEEEEEEEEEEETGSN 282


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)

Query: 114 IVEDKKSGRSSDITSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDN 173
           + E+K   R  D+ SDL ++  S    KT + ++ S++SG+ SEEEE +EE +  E S +
Sbjct: 252 VKEEKMEER--DLLSDLQDI--SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 307

Query: 174 DKKMMKKSADHKNLEVIVTN 193
           ++   ++  + +  E   +N
Sbjct: 308 EESEEEEEEEEEEEEETGSN 327


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 12/129 (9%)

Query: 274 GQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEV 333
           GQ++S     S N P  Y   G  +Q   +SG         G GN G  Q     G G  
Sbjct: 138 GQQQSYGQQQSYNPPQGY---GQQNQYNSSSGGGGG---GGGGGNYGQDQSSMSSGGGSG 191

Query: 334 K-HGGED--GRNNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEG---TKGRQVGSGGD 387
             +G +D  G   SG   ++ RGG     S    G G    + S G    +GR  G GG 
Sbjct: 192 GGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR 251

Query: 388 GERWGSDRG 396
           G   GSDRG
Sbjct: 252 GGMGGSDRG 260


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 44/258 (17%), Positives = 95/258 (36%), Gaps = 23/258 (8%)

Query: 127 TSDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSA---- 182
           + D  ++ +   N++  +   +S +SG  SE+   Q+           +K+ +KS     
Sbjct: 217 SDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEE 276

Query: 183 -------DHKNLEVI----VTNGYDKDGFVQDIQNDIHASS---SLNGRSTEEVKPIDEN 228
                  D+  +E +      N   +D  +   + D    S   S    S EE + +D  
Sbjct: 277 DDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGP 336

Query: 229 LGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGP 288
             ++ + A    Q+ + +  E+V       +   +  Y +  E     E   S T ++  
Sbjct: 337 SSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK 396

Query: 289 FQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVV-----AVEGKGEVKHGGEDGRNN 343
            +       S+  E+  F E+    P + N  + + +     + E + E  H  ED  ++
Sbjct: 397 SESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 456

Query: 344 SGAPHREKRGGETDEFSN 361
             +   ++    T+  S+
Sbjct: 457 QDSSRSKEDSNSTESKSS 474



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 49/228 (21%), Positives = 92/228 (40%), Gaps = 20/228 (8%)

Query: 147 AESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQN 206
           +ESS+    S EE+A E+   + QS+        S DH+ +  +        G   D ++
Sbjct: 48  SESSEGSKVSSEEQANEDPSDSTQSEEG----LGSDDHQYIYRLAGGFSRSTGKGGDDKD 103

Query: 207 DIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVY 266
           D    S  +    ++  P  ++  + G S +   +D +DD ++          DS  +  
Sbjct: 104 DDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDED-SDDTIQASEESAPQGQDSAQDTT 162

Query: 267 CDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENS----GFREDIQVPPGNGNIGNM 322
            +S E    E+ +DS            GG S+Q  E+     G   D +   G+G+  + 
Sbjct: 163 SESRE-LDNEDRVDSKPE---------GGDSTQESESEEHWVGGGSDGESSHGDGSELDD 212

Query: 323 QVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGHRM 370
           + +  +    ++    + R NS A  + K  GE  E +N +   G ++
Sbjct: 213 EGMQSDDPESIRSERGNSRMNS-AGMKSKESGENSEQANTQDSGGSQL 259



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 42/215 (19%), Positives = 79/215 (36%), Gaps = 13/215 (6%)

Query: 147 AESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQN 206
           +E  D G +S++ E+    +G  + ++     K+S +  N E   T        ++    
Sbjct: 208 SELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGE--NSEQANTQDSGGSQLLEHPSR 265

Query: 207 DIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVY 266
            I   S ++    ++   +D+N      +   +  D  ++     TG+     DS  +  
Sbjct: 266 KIFRKSRIS--EEDDRSELDDN-----NTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQ 318

Query: 267 CDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVA 326
            DS E   QEES     + +GP        +    ENS   ++  V    G+  +     
Sbjct: 319 EDSKENLSQEES----QNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSY 374

Query: 327 VEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFSN 361
           VE + +     ED  +       E R  + D  S+
Sbjct: 375 VEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,228,504
Number of Sequences: 37866
Number of extensions: 936683
Number of successful extensions: 5523
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 173
Number of HSP's that attempted gapping in prelim test: 4585
Number of HSP's gapped (non-prelim): 721
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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