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Search of human proteins with 109689703
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109689703 gasdermin-like isoform 1 [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109689703 gasdermin-like isoform 1 [Homo sapiens] 790 0.0
gi|109689711 gasdermin-like isoform 2 [Homo sapiens] 763 0.0
gi|150456463 gasdermin 1 [Homo sapiens] 135 9e-32
gi|83320070 gasdermin D [Homo sapiens] 88 1e-17
gi|13899221 melanoma-derived leucine zipper, extra-nuclear facto... 48 1e-05
gi|4758154 deafness, autosomal dominant 5 protein isoform a [Hom... 42 8e-04
gi|188536092 deafness, autosomal dominant 5 protein isoform a [H... 42 8e-04
gi|111607457 deafness, autosomal recessive 59 [Homo sapiens] 38 0.014
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 38 0.014
gi|118498362 kinectin 1 isoform b [Homo sapiens] 38 0.019
gi|118498356 kinectin 1 isoform a [Homo sapiens] 38 0.019
gi|118498368 kinectin 1 isoform c [Homo sapiens] 38 0.019
gi|33620775 kinectin 1 isoform a [Homo sapiens] 38 0.019
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 35 0.092
gi|110347568 centrosomal protein 152kDa [Homo sapiens] 35 0.092
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 35 0.16
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 35 0.16
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 35 0.16
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 34 0.21
gi|212276104 leucine rich repeat (in FLII) interacting protein 1... 34 0.27
gi|212276096 leucine rich repeat (in FLII) interacting protein 1... 34 0.27
gi|212276070 leucine rich repeat (in FLII) interacting protein 1... 34 0.27
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 34 0.27
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 33 0.46
gi|134152674 rabaptin, RAB GTPase binding effector protein 1 iso... 33 0.46
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 33 0.46
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 33 0.46
gi|156071420 hypothetical protein LOC728912 [Homo sapiens] 32 0.78
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho... 32 0.78
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 32 1.0
>gi|109689703 gasdermin-like isoform 1 [Homo sapiens]
Length = 403
Score = 790 bits (2040), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60
MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD
Sbjct: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60
Query: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120
ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI
Sbjct: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120
Query: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180
SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS
Sbjct: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180
Query: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRN 240
QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRN
Sbjct: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRN 240
Query: 241 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 300
MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK
Sbjct: 241 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 300
Query: 301 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 360
PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ
Sbjct: 301 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 360
Query: 361 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 403
NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS
Sbjct: 361 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 403
>gi|109689711 gasdermin-like isoform 2 [Homo sapiens]
Length = 394
Score = 763 bits (1969), Expect = 0.0
Identities = 393/403 (97%), Positives = 394/403 (97%), Gaps = 9/403 (2%)
Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60
MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD
Sbjct: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60
Query: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120
ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI
Sbjct: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120
Query: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180
SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS
Sbjct: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180
Query: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRN 240
QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETM+ KSLGSEDSRN
Sbjct: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR---------KSLGSEDSRN 231
Query: 241 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 300
MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK
Sbjct: 232 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 291
Query: 301 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 360
PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ
Sbjct: 292 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 351
Query: 361 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 403
NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS
Sbjct: 352 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 394
>gi|150456463 gasdermin 1 [Homo sapiens]
Length = 445
Score = 135 bits (339), Expect = 9e-32
Identities = 131/462 (28%), Positives = 217/462 (46%), Gaps = 88/462 (19%)
Query: 3 SVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLTLM 59
++FE +TR + ++++ GD+ + SL+D RF F LV KR F+G R+ T TL+
Sbjct: 2 TMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLL 61
Query: 60 DILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIK 119
D+L+ G D D+G G K + +D+ E V +PK + + G+ + ++
Sbjct: 62 DVLEP-GSSPSDPTDTGNFGFK------NMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLE 114
Query: 120 ISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYK-- 177
+ ++ + L T++ RKL + PF + ENLY+V E +ETV+E TL+ + +
Sbjct: 115 VQTLSVAPKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEAC 174
Query: 178 ----FWSQIS-QGHLSYKHKGQREVTIPPNRVLSYRVKQLV------------------- 213
F++ + QG +++K VTIP VL++RV+QL+
Sbjct: 175 FSLPFFAPLGLQGSINHK----EAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQT 230
Query: 214 FPNKETMKKDGASSCLGKSLGS--EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCL 271
FP E ++ +G E R +KE+++ ++ L+ + +L+SL+K L
Sbjct: 231 FPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLL 290
Query: 272 GKEDIRQDLEQRVSEVLISG-ELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 330
GK+ QDLE + L G E+ +E K +L L + AIL F+ AL E
Sbjct: 291 GKKKELQDLELALEGALDKGHEVTLEALPKDVL---------LSKEAVGAILYFVGALTE 341
Query: 331 LSEEQQ-FVAEALEKGTLPLLKDQVKSVMEQNW--------------------------- 362
LSE QQ + +++EK LP+ V+S MEQN+
Sbjct: 342 LSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTE 401
Query: 363 -------DELASSPPDMDYDPEA-RILCALYVVVSILLELAE 396
E+ S P +DP+ LCALY +S+L +L +
Sbjct: 402 ALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTK 443
>gi|83320070 gasdermin D [Homo sapiens]
Length = 484
Score = 88.2 bits (217), Expect = 1e-17
Identities = 122/494 (24%), Positives = 207/494 (41%), Gaps = 107/494 (21%)
Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLT 57
M S FE + R VV+E+D GG+ I V SL + F+ + LV K + F+ R+ L+
Sbjct: 1 MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS 60
Query: 58 LMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDS--TGELIVRLPKEITISGSFQGFHH 115
+ DIL+ D + ++ G F D +D G + + P + I+G
Sbjct: 61 IKDILEPDAAE--PDVQRG-----RSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDS 113
Query: 116 QKIKISENRIS---QQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLK 171
++ +S + L R L++ + + +R +N+Y+VTE L+T KE +
Sbjct: 114 SSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVT 173
Query: 172 SDRQYKFWSQIS-----------QGHLSYKHKGQREVTIPPNRVLSYRVKQLV------- 213
+ + + S QGHLS K + VTIP L++RV QLV
Sbjct: 174 RTHKREGSGRFSLPGATCLQGEGQGHLSQK----KTVTIPSGSTLAFRVAQLVIDSDLDV 229
Query: 214 --FPNK------------ETMKKDGASSCLGKSLG-------------------SEDSRN 240
FP+K + +GA L L +ED +
Sbjct: 230 LLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQG 289
Query: 241 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH-MEDPD 299
++ ++E + L+ L E + +L L L + + LE+ + + G + ++ P
Sbjct: 290 LRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPA 349
Query: 300 KPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQ-QFVAEALEKGTLPLLKDQVKSVM 358
+L L ++G+LV A ++ L AL LSE Q + +AEALE TL + V S++
Sbjct: 350 GAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLL 409
Query: 359 EQN--WD-------------------------------ELASSPPDMDYDPEAR-ILCAL 384
EQ+ W EL P + ++P+A+ +CAL
Sbjct: 410 EQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCAL 469
Query: 385 YVVVSILLELAEGP 398
Y +++L L++ P
Sbjct: 470 YASLALLSGLSQEP 483
>gi|13899221 melanoma-derived leucine zipper, extra-nuclear factor
[Homo sapiens]
Length = 508
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/237 (24%), Positives = 102/237 (43%), Gaps = 20/237 (8%)
Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKR----TFFGCRHYT-TG 55
M S+ E I++ +VKE+ + D+ V+ L+ A + R F ++ +K+ +F+ Y
Sbjct: 1 MPSMLERISKNLVKEIGSK-DLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVE 59
Query: 56 LTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHH 115
+L DIL+ L++ + G F + ++ V + E+++SG H
Sbjct: 60 FSLNDILEPSSSV----LETVVTGP-FHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHG 114
Query: 116 QKIKISENRISQQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLKSDR 174
++ I L + RKL P + R +NLY+VTE +E + L
Sbjct: 115 CSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSS 174
Query: 175 QYKFWSQISQGHLSYKHKGQRE--------VTIPPNRVLSYRVKQLVFPNKETMKKD 223
+I+ K +GQ E +T+ V++Y+ KQLV K + D
Sbjct: 175 SVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISD 231
>gi|4758154 deafness, autosomal dominant 5 protein isoform a [Homo
sapiens]
Length = 496
Score = 42.4 bits (98), Expect = 8e-04
Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 5/66 (7%)
Query: 4 VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGC----RHYTTGLTLM 59
+F + TR ++E+DA GD+IAV +L D+D+ + LV +K+ F+ C ++ LTL
Sbjct: 1 MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFW-CWQRPKYQFLSLTLG 59
Query: 60 DILDTD 65
D+L D
Sbjct: 60 DVLIED 65
>gi|188536092 deafness, autosomal dominant 5 protein isoform a
[Homo sapiens]
Length = 496
Score = 42.4 bits (98), Expect = 8e-04
Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 5/66 (7%)
Query: 4 VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGC----RHYTTGLTLM 59
+F + TR ++E+DA GD+IAV +L D+D+ + LV +K+ F+ C ++ LTL
Sbjct: 1 MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFW-CWQRPKYQFLSLTLG 59
Query: 60 DILDTD 65
D+L D
Sbjct: 60 DVLIED 65
>gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]
Length = 352
Score = 38.1 bits (87), Expect = 0.014
Identities = 38/147 (25%), Positives = 64/147 (43%), Gaps = 23/147 (15%)
Query: 4 VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHY---TTGLTLMD 60
+F T+ VK++ GG ++ V SL +AD+++ LV +K+ F Y +T TL D
Sbjct: 1 MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRYKFTSTPFTLKD 60
Query: 61 ILDTDGD-----------KWLDELDSGLQGQKAEFQILD---NVDSTGELIVR------L 100
IL D + + DE D L G++ + D NV + + V+
Sbjct: 61 ILLGDREISAGISSYQLLNYEDESDVSLYGRRGNHIVNDVGINVAGSDSIAVKASFGIVT 120
Query: 101 PKEITISGSFQGFHHQKIKISENRISQ 127
E+ +S + +KI + I Q
Sbjct: 121 KHEVEVSTLLKEITTRKINFDHSLIRQ 147
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 38.1 bits (87), Expect = 0.014
Identities = 65/289 (22%), Positives = 134/289 (46%), Gaps = 37/289 (12%)
Query: 78 QGQKAEFQILDNVDSTGELIVRLPKEI-TISGSFQGFHHQKIKISENRISQQYLATLENR 136
Q +K E Q+ N++ + + K+I + G + QK ++ EN++ QQ +
Sbjct: 949 QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTEL-ENKLQQQLTQAAQEL 1007
Query: 137 KLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQRE 196
++E I+ +N Y ++ ET K+ L+SD Y S++ K + +
Sbjct: 1008 AAEKE------KISVLQNNY--EKSQETFKQ--LQSDF-YGRESELLATRQDLKSV-EEK 1055
Query: 197 VTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLT 256
+++ ++S R Q+ NK + A + L +DS +++L++ L+D+
Sbjct: 1056 LSLAQEDLISNR-NQIGNQNKLIQELKTAKATL-----EQDSAKKEQQLQERCKALQDIQ 1109
Query: 257 EE---KRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVL 313
+E K K+++N +K E+I+ E+ ++++ + H + K +++L +A +L
Sbjct: 1110 KEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKE-ITNLKDAKQLL 1168
Query: 314 VEARAKAILDFLDALLELSEEQQFVAEAL--EKGTLPLLKDQVKSVMEQ 360
++ + LEL + + A+ EK +LKDQVK E+
Sbjct: 1169 IQQK-----------LELQGKADSLKAAVEQEKRNQQILKDQVKKEEEE 1206
Score = 30.4 bits (67), Expect = 3.0
Identities = 72/331 (21%), Positives = 141/331 (42%), Gaps = 30/331 (9%)
Query: 53 TTGLTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQG 112
TT L + D + +L+S L+ K ++ L+ T EL ++ K S +
Sbjct: 687 TTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ--KTEELEGQIKKLEADSLEVKA 744
Query: 113 FHHQKIKISENRISQQYLATLENRKLKRELPFSFRSIN-TRENLYLVTETLETVKEETLK 171
Q ++ + + L +L ++L ++ TR +L +E LE++K++ K
Sbjct: 745 SKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTK 804
Query: 172 SDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVK-QLVFPNKETM---------K 221
+ + + Q + LS + K Q E NR+ + + Q V KE + K
Sbjct: 805 QEEEKQILKQDFET-LSQETKIQHEEL--NNRIQTTVTELQKVKMEKEALMTELSTVKDK 861
Query: 222 KDGASSCLGKSLGSEDSRNMKEK--LEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQD 279
S L S + N K K + D+E K+L + + + N+L + ++++++
Sbjct: 862 LSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKE---QKELKKS 918
Query: 280 LEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLV--EARAKAILDFLDALLELSEEQQF 337
LE+ E S +L +E + L A L E + + ++ L + SE+++
Sbjct: 919 LEK---EKEASHQLKLE--LNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK 973
Query: 338 VAEAL--EKGTLPLLKDQVKSVMEQNWDELA 366
EAL E L K ++++ ++Q + A
Sbjct: 974 QIEALQGELKIAVLQKTELENKLQQQLTQAA 1004
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 37.7 bits (86), Expect = 0.019
Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%)
Query: 236 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 295
++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E + V + ++
Sbjct: 840 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 896
Query: 296 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 350
++ +S F ++++ + L L+A+L +LS + Q + + ++ L
Sbjct: 897 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 950
Query: 351 KDQVKSVMEQNWDELASSPP 370
K Q++ + +QN+ + +S PP
Sbjct: 951 KSQIEQLKQQNYQQASSFPP 970
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.7 bits (86), Expect = 0.019
Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%)
Query: 236 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 295
++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E + V + ++
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919
Query: 296 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 350
++ +S F ++++ + L L+A+L +LS + Q + + ++ L
Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973
Query: 351 KDQVKSVMEQNWDELASSPP 370
K Q++ + +QN+ + +S PP
Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 37.7 bits (86), Expect = 0.019
Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%)
Query: 236 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 295
++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E + V + ++
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919
Query: 296 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 350
++ +S F ++++ + L L+A+L +LS + Q + + ++ L
Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973
Query: 351 KDQVKSVMEQNWDELASSPP 370
K Q++ + +QN+ + +S PP
Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.7 bits (86), Expect = 0.019
Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%)
Query: 236 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 295
++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E + V + ++
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919
Query: 296 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 350
++ +S F ++++ + L L+A+L +LS + Q + + ++ L
Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973
Query: 351 KDQVKSVMEQNWDELASSPP 370
K Q++ + +QN+ + +S PP
Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 35.4 bits (80), Expect = 0.092
Identities = 55/235 (23%), Positives = 109/235 (46%), Gaps = 29/235 (12%)
Query: 120 ISENRISQQYLAT---LENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLKSDRQ 175
+ EN+ + LA E K +E+ T E+L + L T K + LK +Q
Sbjct: 580 LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK--QQ 637
Query: 176 YKFWSQISQGHLSYKHKGQREVTIPPNRVL-SYRVKQLVFPNKETMKKDGASSCLGKSLG 234
Y Q L K + ++E + ++ ++++ N++T++K +SL
Sbjct: 638 Y----QTEMEKLREKCEQEKETLLKDKEIIFQAHIEEM---NEKTLEKLDVKQTELESLS 690
Query: 235 SEDSRNMK--EKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGE 292
SE S +K KLE+ SVLKD T++ ++++ + ++ + +Q+V ++ E
Sbjct: 691 SELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM------DEQKNHHQQQVDSIIKEHE 744
Query: 293 LHMEDPDKPLLSSLFNAAGVLVEARAK------AILDFLDALLELSEEQQFVAEA 341
+ ++ +K L + N +L++ R K A ++ L+A ++ SE + A A
Sbjct: 745 VSIQRTEKALKDQI-NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASA 798
>gi|110347568 centrosomal protein 152kDa [Homo sapiens]
Length = 1654
Score = 35.4 bits (80), Expect = 0.092
Identities = 43/203 (21%), Positives = 89/203 (43%), Gaps = 24/203 (11%)
Query: 102 KEITISGSFQGFHHQKIKISENRISQQYLATLE--NRKLKRELPFSFRSINTRE-NLYLV 158
+EIT S +F+G Q + +EN + L+ N+ +R+L +N E + +
Sbjct: 210 QEITGSDTFEGLQQQFLGANENSAENMQIIQLQVLNKAKERQLENLIEKLNESERQIRYL 269
Query: 159 TETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPN-RVLSYRVKQLVFPNK 217
L +K+E + + + +++ +RE+ + + L +++ L +
Sbjct: 270 NHQLVIIKDE------KDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQALKVNEE 323
Query: 218 ETMKKDGASSCLGKSLGSE-----DSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLG 272
+ +KK + +SL + S +++ E ES++ LT++ + VL SL K L
Sbjct: 324 QMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESIVMGLTKKYEEQVL-SLQKNLD 382
Query: 273 --------KEDIRQDLEQRVSEV 287
+EDI L+ V ++
Sbjct: 383 ATVTALKEQEDICSRLKDHVKQL 405
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 34.7 bits (78), Expect = 0.16
Identities = 35/157 (22%), Positives = 67/157 (42%), Gaps = 28/157 (17%)
Query: 158 VTETLETVKEETLKSDRQYKFWSQISQGHLSYKH-----------KGQREVTIPPNRVLS 206
+T+ + VKE T + + K+ + Q KH K + +V N L
Sbjct: 2293 ITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLRLANHQLD 2352
Query: 207 YRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLK--DLTEEKRKDVL 264
+L+ + + GA S + D+ +KEK++D+E+ LK DL ++ K+ +
Sbjct: 2353 KEKAELIHQIEANKDQSGAESTI------PDADQLKEKIKDLETQLKMSDLEKQHLKEEI 2406
Query: 265 NSLAKCLGK---------EDIRQDLEQRVSEVLISGE 292
L K L ED++ + ++ V + ++ E
Sbjct: 2407 KKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEE 2443
>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
sapiens]
Length = 796
Score = 34.7 bits (78), Expect = 0.16
Identities = 66/293 (22%), Positives = 121/293 (41%), Gaps = 55/293 (18%)
Query: 100 LPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSI-----NTREN 154
LP T+S F + K+S++ + + +N K +E+P + ++I ++R
Sbjct: 286 LPFRETVSKFHVHFCRKCKKLSKSEMHRGK----KNEKNNKEIPITGKNITDLKFHSRVP 341
Query: 155 LYLVTETLETVKEETLKSDRQ---YKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211
Y ++ L+ K E +RQ K S IS+ + K E + + L +K+
Sbjct: 342 RYTLS-FLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 400
Query: 212 LVFPNKETMKKDGASSCLGKSLGSE--DSRNMKEKLEDMESVLKDLTEEK---------- 259
V K+ M+ + + L + ++++ +K+E E LK+L EEK
Sbjct: 401 SVQIQKKVMELESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKT 460
Query: 260 ----------------RKDVLNSLAKCLGKEDIRQDLE-QRVSEVL--ISGELHMEDPDK 300
+ +VL K L +++I+ LE Q++ E L + + H D
Sbjct: 461 EEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQSDM 520
Query: 301 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 353
++++ N + +EA IL D E LEK T LLK++
Sbjct: 521 AIVNNENNRMSIEMEAMKTNILLIQDE-----------KEMLEKKTHQLLKEK 562
>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
sapiens]
Length = 833
Score = 34.7 bits (78), Expect = 0.16
Identities = 66/293 (22%), Positives = 121/293 (41%), Gaps = 55/293 (18%)
Query: 100 LPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSI-----NTREN 154
LP T+S F + K+S++ + + +N K +E+P + ++I ++R
Sbjct: 323 LPFRETVSKFHVHFCRKCKKLSKSEMHRGK----KNEKNNKEIPITGKNITDLKFHSRVP 378
Query: 155 LYLVTETLETVKEETLKSDRQ---YKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211
Y ++ L+ K E +RQ K S IS+ + K E + + L +K+
Sbjct: 379 RYTLS-FLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 437
Query: 212 LVFPNKETMKKDGASSCLGKSLGSE--DSRNMKEKLEDMESVLKDLTEEK---------- 259
V K+ M+ + + L + ++++ +K+E E LK+L EEK
Sbjct: 438 SVQIQKKVMELESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKT 497
Query: 260 ----------------RKDVLNSLAKCLGKEDIRQDLE-QRVSEVL--ISGELHMEDPDK 300
+ +VL K L +++I+ LE Q++ E L + + H D
Sbjct: 498 EEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQSDM 557
Query: 301 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 353
++++ N + +EA IL D E LEK T LLK++
Sbjct: 558 AIVNNENNRMSIEMEAMKTNILLIQDE-----------KEMLEKKTHQLLKEK 599
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 34.3 bits (77), Expect = 0.21
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 15/131 (11%)
Query: 237 DSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHME 296
D+ E+LE+ + L +E + V AKC E +Q L+ V ++++ E
Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS-- 1438
Query: 297 DPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKD--QV 354
NAA ++ + + L + EE Q EA +K + L + +V
Sbjct: 1439 -----------NAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 1487
Query: 355 KSVMEQNWDEL 365
K+V E++ D+L
Sbjct: 1488 KNVYEESLDQL 1498
>gi|212276104 leucine rich repeat (in FLII) interacting protein 1
isoform 5 [Homo sapiens]
Length = 752
Score = 33.9 bits (76), Expect = 0.27
Identities = 61/271 (22%), Positives = 105/271 (38%), Gaps = 34/271 (12%)
Query: 116 QKIKISENRISQQYL-ATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDR 174
++IK S + ++Y A + N +L E ++T +++ L E E+ +S R
Sbjct: 102 REIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELE------EQLAESRR 155
Query: 175 QY----KFWSQISQGH--LSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSC 228
QY K + + H L ++ +E +L K + N E S
Sbjct: 156 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE---KHGIILNSEIATNGETSDT 212
Query: 229 LGKSLGSEDSRNMKEKLEDMESVLKD-LTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEV 287
L ++ KE+L ++S L +V N + +GK +I + E+
Sbjct: 213 LNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEK----- 267
Query: 288 LISGELHMEDPDKPLLSSLFNAAGVLVEARAKA--ILDFLDALLELSEEQQFVAEALEKG 345
E H ED K + AG E + + FL L + E+Q ++ LE
Sbjct: 268 ----EQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESS 323
Query: 346 TLPLLKDQVKSVMEQNWDELASSPPDMDYDP 376
+LP QV+S +E+ +P D P
Sbjct: 324 SLPENTVQVES------NEVMGAPDDRTRTP 348
>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
isoform 3 [Homo sapiens]
Length = 808
Score = 33.9 bits (76), Expect = 0.27
Identities = 62/276 (22%), Positives = 106/276 (38%), Gaps = 36/276 (13%)
Query: 111 QGFHHQKIKISENRISQQYL-ATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEET 169
QG K ++E + ++Y A + N +L E ++T +++ L E E+
Sbjct: 155 QGLKEMKDSLAE--VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELE------EQL 206
Query: 170 LKSDRQY----KFWSQISQGH--LSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKD 223
+S RQY K + + H L ++ +E +L K + N E
Sbjct: 207 AESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE---KHGIILNSEIATNG 263
Query: 224 GASSCLGKSLGSEDSRNMKEKLEDMESVLKD-LTEEKRKDVLNSLAKCLGKEDIRQDLEQ 282
S L ++ KE+L ++S L +V N + +GK +I + E+
Sbjct: 264 ETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEK 323
Query: 283 RVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKA--ILDFLDALLELSEEQQFVAE 340
E H ED K + AG E + + FL L + E+Q ++
Sbjct: 324 ---------EQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQ 374
Query: 341 ALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDP 376
LE +LP QV+S +E+ +P D P
Sbjct: 375 ILESSSLPENTVQVES------NEVMGAPDDRTRTP 404
>gi|212276070 leucine rich repeat (in FLII) interacting protein 1
isoform 4 [Homo sapiens]
Length = 784
Score = 33.9 bits (76), Expect = 0.27
Identities = 61/271 (22%), Positives = 105/271 (38%), Gaps = 34/271 (12%)
Query: 116 QKIKISENRISQQYL-ATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDR 174
++IK S + ++Y A + N +L E ++T +++ L E E+ +S R
Sbjct: 134 REIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELE------EQLAESRR 187
Query: 175 QY----KFWSQISQGH--LSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSC 228
QY K + + H L ++ +E +L K + N E S
Sbjct: 188 QYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE---KHGIILNSEIATNGETSDT 244
Query: 229 LGKSLGSEDSRNMKEKLEDMESVLKD-LTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEV 287
L ++ KE+L ++S L +V N + +GK +I + E+
Sbjct: 245 LNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEK----- 299
Query: 288 LISGELHMEDPDKPLLSSLFNAAGVLVEARAKA--ILDFLDALLELSEEQQFVAEALEKG 345
E H ED K + AG E + + FL L + E+Q ++ LE
Sbjct: 300 ----EQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESS 355
Query: 346 TLPLLKDQVKSVMEQNWDELASSPPDMDYDP 376
+LP QV+S +E+ +P D P
Sbjct: 356 SLPENTVQVES------NEVMGAPDDRTRTP 380
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 33.9 bits (76), Expect = 0.27
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 271 LGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 330
LG+E++ +E + VLI+ L D SSL N A L E + + DALL+
Sbjct: 432 LGQEELFVAVEMLSAVVLINRALEARDASG-FWSSLVNPATGLAEVEGENAQRYFDALLK 490
Query: 331 LSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDEL 365
L +E+ + L L QV + ++ D +
Sbjct: 491 LRQERGMGEDFLSWNDLQATVSQVNAQTQEETDRV 525
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 33.1 bits (74), Expect = 0.46
Identities = 67/315 (21%), Positives = 124/315 (39%), Gaps = 48/315 (15%)
Query: 70 LDELDSGLQGQKAEFQI-LDNVDSTGELIVR----LPKEITISGSFQGFHHQKIKISENR 124
L + L+ +K+EF++ LD+V S E I++ L K H K + ++
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 125 I----SQQYLATLENRKLKRELPFSFRSIN--TRENLYLVTETLETVK---EETLKSDRQ 175
+ SQ+ EN +L R+L I+ TR L T+ LE +K EE +K+
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKL-TYTQQLEDLKRQLEEEVKAKNA 1328
Query: 176 YKFWSQISQGH---LSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKS 232
Q ++ L +++ + E RVLS K + ++
Sbjct: 1329 LAHALQSARHDCDLLREQYEEETEAKAELQRVLS---------------KANSEVAQWRT 1373
Query: 233 LGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGE 292
D+ E+LE+ + L +E + V AKC E + L+ + ++++ E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433
Query: 293 LHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKD 352
NAA ++ + + L + EE Q E+ +K L +
Sbjct: 1434 RS-------------NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTE 1480
Query: 353 --QVKSVMEQNWDEL 365
++K+ E++ + L
Sbjct: 1481 LFKLKNAYEESLEHL 1495
>gi|134152674 rabaptin, RAB GTPase binding effector protein 1
isoform 2 [Homo sapiens]
Length = 829
Score = 33.1 bits (74), Expect = 0.46
Identities = 44/206 (21%), Positives = 92/206 (44%), Gaps = 13/206 (6%)
Query: 161 TLETVKEETLKSDRQYKFWSQISQGHLS---YKHKGQREVTIPPNRVLSYRVKQLVFPNK 217
+L+ V +ET++ D +++F ++ Q Y+ +RE+ R LS ++ N+
Sbjct: 116 SLQAVMKETVR-DYEHQFHLRLEQERTQWAQYRESAEREIA-DLRRRLSEGQEEENLENE 173
Query: 218 ETMKKDGASSCLGKSLGSE-DSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDI 276
++ A + E + +K+KL + E +K+L K K++ + L ++
Sbjct: 174 MKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLE---AEKSC 230
Query: 277 RQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARA---KAILDFLDALLELSE 333
R DLE V+ + + ED +K L L +L + R + + A + E
Sbjct: 231 RTDLEMYVAVLNTQKSVLQEDAEK-LRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLE 289
Query: 334 EQQFVAEALEKGTLPLLKDQVKSVME 359
Q+ + +++ + L +Q++ V E
Sbjct: 290 SQRLLMRDMQRMEIVLTSEQLRQVEE 315
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 33.1 bits (74), Expect = 0.46
Identities = 38/134 (28%), Positives = 52/134 (38%), Gaps = 17/134 (12%)
Query: 190 KHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDM- 248
KHK + + L R+ Q K G+S LG S GS M K+E +
Sbjct: 140 KHKKSLQKLVSDWNTLKSRLSQAT-------KNSGSSQGLGGSPGSHSHTTMANKVETLK 192
Query: 249 --ESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSL 306
E LK E+ R + L L + KED + R+ E+ D + LSSL
Sbjct: 193 EEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEI-------QADYHRRSLSSL 245
Query: 307 FNAAGVLVEARAKA 320
A L E +A
Sbjct: 246 DTALAELRENHGQA 259
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 33.1 bits (74), Expect = 0.46
Identities = 44/206 (21%), Positives = 92/206 (44%), Gaps = 13/206 (6%)
Query: 161 TLETVKEETLKSDRQYKFWSQISQGHLS---YKHKGQREVTIPPNRVLSYRVKQLVFPNK 217
+L+ V +ET++ D +++F ++ Q Y+ +RE+ R LS ++ N+
Sbjct: 116 SLQAVMKETVR-DYEHQFHLRLEQERTQWAQYRESAEREIA-DLRRRLSEGQEEENLENE 173
Query: 218 ETMKKDGASSCLGKSLGSE-DSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDI 276
++ A + E + +K+KL + E +K+L K K++ + L ++
Sbjct: 174 MKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLE---AEKSC 230
Query: 277 RQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARA---KAILDFLDALLELSE 333
R DLE V+ + + ED +K L L +L + R + + A + E
Sbjct: 231 RTDLEMYVAVLNTQKSVLQEDAEK-LRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLE 289
Query: 334 EQQFVAEALEKGTLPLLKDQVKSVME 359
Q+ + +++ + L +Q++ V E
Sbjct: 290 SQRLLMRDMQRMEIVLTSEQLRQVEE 315
>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
Length = 790
Score = 32.3 bits (72), Expect = 0.78
Identities = 49/245 (20%), Positives = 101/245 (41%), Gaps = 34/245 (13%)
Query: 132 TLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKH 191
T E K+ L S + + ++++ E +EE K + + + + +
Sbjct: 426 TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES 485
Query: 192 --KGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDME 249
+G ++IPP R+ SY+ F + E + C+ +G R + K ED E
Sbjct: 486 WDEGYSTLSIPPERLASYQSYSSTFHSLEEQQ-----VCMAVDIGRH--RWDQVKKEDQE 538
Query: 250 S----VLKDLTEEKRKDVL-NSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLS 304
+ + ++L +EK +VL +SL +C + L + D +P S
Sbjct: 539 ATGPRLSRELLDEKEPEVLQDSLDRCYSTPSV---------------YLGLTDSCQPYRS 583
Query: 305 SLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDE 364
+ + VL + R +D +D + + E ++ + + + LL ++ V++ + D
Sbjct: 584 AFY----VLEQQRIGLAVD-MDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDR 638
Query: 365 LASSP 369
S+P
Sbjct: 639 CYSTP 643
>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
sapiens]
Length = 790
Score = 32.3 bits (72), Expect = 0.78
Identities = 49/245 (20%), Positives = 101/245 (41%), Gaps = 34/245 (13%)
Query: 132 TLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKH 191
T E K+ L S + + ++++ E +EE K + + + + +
Sbjct: 426 TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES 485
Query: 192 --KGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDME 249
+G ++IPP R+ SY+ F + E + C+ +G R + K ED E
Sbjct: 486 WDEGYSTLSIPPERLASYQSYSSTFHSLEEQQ-----VCMAVDIGRH--RWDQVKKEDQE 538
Query: 250 S----VLKDLTEEKRKDVL-NSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLS 304
+ + ++L +EK +VL +SL +C + L + D +P S
Sbjct: 539 ATGPRLSRELLDEKEPEVLQDSLDRCYSTPSV---------------YLGLTDSCQPYRS 583
Query: 305 SLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDE 364
+ + VL + R +D +D + + E ++ + + + LL ++ V++ + D
Sbjct: 584 AFY----VLEQQRIGLAVD-MDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDR 638
Query: 365 LASSP 369
S+P
Sbjct: 639 CYSTP 643
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 32.0 bits (71), Expect = 1.0
Identities = 52/233 (22%), Positives = 92/233 (39%), Gaps = 33/233 (14%)
Query: 34 FRCFHLVGEKRTFFGCRHYTTGLTLM-DILDTDGDKWLDELDSGLQGQKA----EFQILD 88
F C ++ K+ F R T +TL D+ D G L G + Q A +FQ L
Sbjct: 628 FVCDNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGT-----LSGGARSQAASILTKFQELK 682
Query: 89 NVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRS 148
+V EL ++ + + G + K + + QQ+ E L +
Sbjct: 683 DVQD--ELRIKENELRALEEELAGLKNTAEKYRQ--LKQQWEMKTEEADLLQTKLQQSSY 738
Query: 149 INTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYR 208
+E L + +T+E EETLK+ ++ + K + + VL +
Sbjct: 739 HKQQEELDALKKTIEE-SEETLKNTKEIQ-------------RKAEEKY-----EVLENK 779
Query: 209 VKQLVFPNKETMKKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRK 261
+K + +K K+ S+ MKEK +++E++ +L E KR+
Sbjct: 780 MKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKRE 832
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,213,013
Number of Sequences: 37866
Number of extensions: 604097
Number of successful extensions: 2352
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 2289
Number of HSP's gapped (non-prelim): 124
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.