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Search of human proteins with 109627650
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109627650 coronin 6 [Homo sapiens]
(472 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109627650 coronin 6 [Homo sapiens] 966 0.0
gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo sa... 698 0.0
gi|65787364 coronin, actin binding protein, 1B [Homo sapiens] 690 0.0
gi|14149734 coronin, actin binding protein, 1B [Homo sapiens] 690 0.0
gi|5902134 coronin, actin binding protein, 1A [Homo sapiens] 637 0.0
gi|148529011 coronin, actin binding protein, 2B [Homo sapiens] 410 e-114
gi|209529711 coronin, actin binding protein, 2A [Homo sapiens] 399 e-111
gi|16554585 coronin, actin binding protein, 2A [Homo sapiens] 399 e-111
gi|168229161 coronin 7 [Homo sapiens] 219 4e-57
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 75 1e-13
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 75 1e-13
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 75 1e-13
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 71 2e-12
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 70 5e-12
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 70 5e-12
gi|23199987 WD repeat domain 5B [Homo sapiens] 67 3e-11
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 66 6e-11
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 66 6e-11
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 66 6e-11
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 66 6e-11
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 64 2e-10
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 63 7e-10
gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens] 61 2e-09
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 60 3e-09
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 60 3e-09
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 60 3e-09
gi|21071067 TBP-associated factor 5 [Homo sapiens] 59 7e-09
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 59 7e-09
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 59 7e-09
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 59 7e-09
>gi|109627650 coronin 6 [Homo sapiens]
Length = 472
Score = 966 bits (2498), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFI 60
MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFI
Sbjct: 1 MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFI 60
Query: 61 VLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNI 120
VLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNI
Sbjct: 61 VLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNI 120
Query: 121 TEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHS 180
TEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHS
Sbjct: 121 TEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHS 180
Query: 181 VCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTR 240
VCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTR
Sbjct: 181 VCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTR 240
Query: 241 MSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEP 300
MSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEP
Sbjct: 241 MSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEP 300
Query: 301 PFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQD 360
PFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQD
Sbjct: 301 PFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQD 360
Query: 361 DLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPR 420
DLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPR
Sbjct: 361 DLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPR 420
Query: 421 RSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD 472
RSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD
Sbjct: 421 RSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD 472
>gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo
sapiens]
Length = 474
Score = 698 bits (1801), Expect = 0.0
Identities = 322/471 (68%), Positives = 397/471 (84%), Gaps = 6/471 (1%)
Query: 3 RRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVL 62
RRVVRQSKFRHVFGQA K DQ Y+DIRVS+VTWDSSFCAVNP+F+AII+EA GGGAF+VL
Sbjct: 2 RRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVL 61
Query: 63 PLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITE 122
PL KTGR+DK+YP V GHT PVLDIDWCPHND VIAS S+D T+MVWQIP+ ++TE
Sbjct: 62 PLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTE 121
Query: 123 PIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
P++ LEGHSKRVGI++WHPTARNVLLSAG DN IIIWNVGTGE L++LDDMH D+I++V
Sbjct: 122 PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVS 181
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMS 242
WN NGSL+ T KDK +R+IDPRK ++VAE+ AHEG RPMRA+F G++FTTGF+RMS
Sbjct: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMS 241
Query: 243 QRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPF 302
+R+L LW+P N +EP+AL EMDTSNGVLLPFYDPD+SI+YLCGKGDSSIRYFEITDE P+
Sbjct: 242 ERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPY 301
Query: 303 VHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDL 362
VHYLNTFSSKEPQRGMG+MPKRGLDV+KCEIARF+KLHERKCEPIIMTVPRKSDLFQDDL
Sbjct: 302 VHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDL 361
Query: 363 YPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPR-- 420
YPDT GPE ALEA+EW G++A+P+LISL+ GY+P K+R+L+V K+NILD +P + +
Sbjct: 362 YPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKCD 421
Query: 421 ----RSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCEL 467
++ A + + L+ +L+EIK++++ + Q++RI+ LE + ++
Sbjct: 422 LISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKI 472
>gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 690 bits (1780), Expect = 0.0
Identities = 326/484 (67%), Positives = 392/484 (80%), Gaps = 16/484 (3%)
Query: 3 RRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVL 62
R+VVRQSKFRHVFGQ K DQ YEDIRVS+VTWDS+FCAVNPKFLA+IVEA GGGAF+VL
Sbjct: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
Query: 63 PLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITE 122
PL+KTGR+DK YP V GHT PVLDIDWCPHND VIAS S+D T+MVWQIP+ +TE
Sbjct: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
Query: 123 PIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
P++ LEGH+KRVGI++WHPTARNVLLSAG DNV++IWNVGT E L LD +HPD+I++V
Sbjct: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMS 242
WN NGSL + CKDK++RIIDPR+G +VAER AHEG RPMRA+F G +FTTGF+RMS
Sbjct: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMS 243
Query: 243 QRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPF 302
+R+L LWDP N EEP+ALQE+D+SNG LLPFYDPD+S+VY+CGKGDSSIRYFEIT+EPP+
Sbjct: 244 ERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPY 303
Query: 303 VHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDL 362
+H+LNTF+SKEPQRGMG MPKRGL+VSKCEIARFYKLHERKCEPI+MTVPRKSDLFQDDL
Sbjct: 304 IHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDL 363
Query: 363 YPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNIL-DVRPPSGPRR 421
YPDT GPE ALEA+EW+SG+DA+P+LISLR+ YVP K R+L++++RN+L D RP P
Sbjct: 364 YPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGS 423
Query: 422 SQ---------------SASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCE 466
S S S A + LE +++E++ALR V+ Q RI LE L
Sbjct: 424 SHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGR 483
Query: 467 LVDG 470
+ +G
Sbjct: 484 MENG 487
>gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 690 bits (1780), Expect = 0.0
Identities = 326/484 (67%), Positives = 392/484 (80%), Gaps = 16/484 (3%)
Query: 3 RRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVL 62
R+VVRQSKFRHVFGQ K DQ YEDIRVS+VTWDS+FCAVNPKFLA+IVEA GGGAF+VL
Sbjct: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
Query: 63 PLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITE 122
PL+KTGR+DK YP V GHT PVLDIDWCPHND VIAS S+D T+MVWQIP+ +TE
Sbjct: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
Query: 123 PIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
P++ LEGH+KRVGI++WHPTARNVLLSAG DNV++IWNVGT E L LD +HPD+I++V
Sbjct: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMS 242
WN NGSL + CKDK++RIIDPR+G +VAER AHEG RPMRA+F G +FTTGF+RMS
Sbjct: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMS 243
Query: 243 QRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPF 302
+R+L LWDP N EEP+ALQE+D+SNG LLPFYDPD+S+VY+CGKGDSSIRYFEIT+EPP+
Sbjct: 244 ERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPY 303
Query: 303 VHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDL 362
+H+LNTF+SKEPQRGMG MPKRGL+VSKCEIARFYKLHERKCEPI+MTVPRKSDLFQDDL
Sbjct: 304 IHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDL 363
Query: 363 YPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNIL-DVRPPSGPRR 421
YPDT GPE ALEA+EW+SG+DA+P+LISLR+ YVP K R+L++++RN+L D RP P
Sbjct: 364 YPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGS 423
Query: 422 SQ---------------SASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCE 466
S S S A + LE +++E++ALR V+ Q RI LE L
Sbjct: 424 SHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGR 483
Query: 467 LVDG 470
+ +G
Sbjct: 484 MENG 487
>gi|5902134 coronin, actin binding protein, 1A [Homo sapiens]
Length = 461
Score = 637 bits (1642), Expect = 0.0
Identities = 310/463 (66%), Positives = 378/463 (81%), Gaps = 10/463 (2%)
Query: 1 MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFI 60
MSR+VVR SKFRHVFGQ AKADQ YED+RVS+ TWDS FCAVNPKF+A+I EA GGGAF+
Sbjct: 1 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 60
Query: 61 VLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNI 120
VLPL KTGRVDKN P V GHTAPVLDI WCPHNDNVIAS S+D T+MVW+IPD M +
Sbjct: 61 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 120
Query: 121 TEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLD-DMHPDVIH 179
EP++TLEGH+KRVGI++WH TA+NVLLSAG DNVI++W+VGTG +L+L ++HPD I+
Sbjct: 121 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 180
Query: 180 SVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFT 239
SV W+ +G L+ T+C+DK +RII+PRKG VVAE+ HEG RP+RAVF +G I TTGF+
Sbjct: 181 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 240
Query: 240 RMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDE 299
RMS+R++ LWD + EEP++LQE+DTS+GVLLPF+DPD++IVYLCGKGDSSIRYFEIT E
Sbjct: 241 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 300
Query: 300 PPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQ 359
PF+HYL+ FSSKE QRGMG+MPKRGL+V+KCEIARFYKLHER+CEPI MTVPRKSDLFQ
Sbjct: 301 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 360
Query: 360 DDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGP 419
+DLYP T GP+PAL A+EWL G+DA P+LISL+DGYVPPK RELRV + LD +G
Sbjct: 361 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD----TGR 414
Query: 420 RR-SQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALE 461
RR + AS P S + L EE++ L+ VQ ++R+ LE
Sbjct: 415 RRAAPEASGTPSSD--AVSRLEEEMRKLQATVQELQKRLDRLE 455
>gi|148529011 coronin, actin binding protein, 2B [Homo sapiens]
Length = 480
Score = 410 bits (1054), Expect = e-114
Identities = 211/468 (45%), Positives = 298/468 (63%), Gaps = 17/468 (3%)
Query: 7 RQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAK 66
R SKFR+V+G+ A + ++ I ++K D+ FCAVN +FLAI+ E+ GGG+F+V+PL +
Sbjct: 13 RSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQ 72
Query: 67 TGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIIT 126
TGR++ NYP V GH VLDI W P DN+IAS S+DT++ +W+IP+ RN+TE ++
Sbjct: 73 TGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLE 132
Query: 127 LEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSN 186
L GHS+RVG++ WHPT N+L SAG D ++IWN+ GE + + D H DVI + +N++
Sbjct: 133 LHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEP-VKMIDCHTDVILCMSFNTD 191
Query: 187 GSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFT-RQGHIFTTGFTRMSQRE 245
GSLL TTCKDK LR+I+PR G+V+ E A + R R VF + TTG +R + R+
Sbjct: 192 GSLLTTTCKDKKLRVIEPRSGRVLQE--ANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQ 249
Query: 246 LGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHY 305
+ LWD + P+ +E+D +G+L PFYD D+ ++YL GKGD +IRY+EI+ E P++ Y
Sbjct: 250 IALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSY 309
Query: 306 LNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERK--CEPIIMTVPRKSDLFQDDLY 363
L F S PQ+G+G MPK GLDVS CE+ RFYKL K EPI M VPR+SD +Q+D+Y
Sbjct: 310 LMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIY 369
Query: 364 PDTPGPEPALEADEWLSGQDAEPVLISLRDGY---------VPPKHRELRVTKRNILDVR 414
P TPG EPAL DEWL G + +PVL+SL++GY P K ++ V N +D+
Sbjct: 370 PMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVV--NGIDLL 427
Query: 415 PPSGPRRSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALEN 462
PR QQ + L EE+ R++ + + L N
Sbjct: 428 ENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRN 475
>gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 399 bits (1026), Expect = e-111
Identities = 201/443 (45%), Positives = 286/443 (64%), Gaps = 10/443 (2%)
Query: 7 RQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAK 66
R SKFRHVFG+ A + Y+ + +++ D+ FCAVNP F+A++ E GGGAF+V+PL +
Sbjct: 8 RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
Query: 67 TGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIIT 126
TG++D +YP V GH VLD+ W P +D IAS S+D TI +W IP RN+T
Sbjct: 68 TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
Query: 127 LEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVL----LSLDDMHPDVIHSVC 182
L GH++RVG++ WHPTA N+L SAG D ++IWN+ T E + +S H DVI S+
Sbjct: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFT-RQGHIFTTGFTRM 241
+N+NGSLLATTCKD+ +R+IDPR G V+ E A+++G R + +F + +TG +R
Sbjct: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQE--ASYKGHRASKVLFLGNLKKLMSTGTSRW 245
Query: 242 SQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPP 301
+ R++ LWD +N P+ +++D S+GVL PFYD D+S++Y+ GKGD +IRY+E++ + P
Sbjct: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
Query: 302 FVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERK--CEPIIMTVPRKSDLFQ 359
+ YL + S PQ+G+G MPKRGLDVS CEI RFYKL K EPI M VPR+S+ +Q
Sbjct: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
Query: 360 DDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGP 419
+D+YP T G +P+L A EWLSG + +P+L+SLR G + L +R I + P+ P
Sbjct: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPL-PAERPIFNSMAPASP 424
Query: 420 RRSQSASDAPLSQQHTLETLLEE 442
R +LLEE
Sbjct: 425 RLLNQTEKLAAEDGWRSSSLLEE 447
>gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 399 bits (1026), Expect = e-111
Identities = 201/443 (45%), Positives = 286/443 (64%), Gaps = 10/443 (2%)
Query: 7 RQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAK 66
R SKFRHVFG+ A + Y+ + +++ D+ FCAVNP F+A++ E GGGAF+V+PL +
Sbjct: 8 RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
Query: 67 TGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIIT 126
TG++D +YP V GH VLD+ W P +D IAS S+D TI +W IP RN+T
Sbjct: 68 TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
Query: 127 LEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVL----LSLDDMHPDVIHSVC 182
L GH++RVG++ WHPTA N+L SAG D ++IWN+ T E + +S H DVI S+
Sbjct: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFT-RQGHIFTTGFTRM 241
+N+NGSLLATTCKD+ +R+IDPR G V+ E A+++G R + +F + +TG +R
Sbjct: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQE--ASYKGHRASKVLFLGNLKKLMSTGTSRW 245
Query: 242 SQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPP 301
+ R++ LWD +N P+ +++D S+GVL PFYD D+S++Y+ GKGD +IRY+E++ + P
Sbjct: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
Query: 302 FVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERK--CEPIIMTVPRKSDLFQ 359
+ YL + S PQ+G+G MPKRGLDVS CEI RFYKL K EPI M VPR+S+ +Q
Sbjct: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
Query: 360 DDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGP 419
+D+YP T G +P+L A EWLSG + +P+L+SLR G + L +R I + P+ P
Sbjct: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPL-PAERPIFNSMAPASP 424
Query: 420 RRSQSASDAPLSQQHTLETLLEE 442
R +LLEE
Sbjct: 425 RLLNQTEKLAAEDGWRSSSLLEE 447
>gi|168229161 coronin 7 [Homo sapiens]
Length = 925
Score = 219 bits (558), Expect = 4e-57
Identities = 139/426 (32%), Positives = 215/426 (50%), Gaps = 14/426 (3%)
Query: 9 SKFRHVFGQAAKADQAYEDIRVSKVTW---DSSFCAVNPKFLAIIVEAGGGGAFIVLPLA 65
SKFRH G D +++ +T FCA + ++ +GG A VL L
Sbjct: 471 SKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCANKLRVAVPLLSSGGQVA--VLELR 528
Query: 66 KTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPII 125
K GR+ + A V D+ W P + + +A A +D I +W++P +T P
Sbjct: 529 KPGRLPDTALPTLQNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTTPET 588
Query: 126 TLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNS 185
L GH++++ L +HP A NVL S+ D + IW++ G L L H D I S+ W+
Sbjct: 589 VLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKLQG-HQDQIFSLAWSP 647
Query: 186 NGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGH-IFTTGFTRMSQR 244
+G LAT CKD +R+ PR G + +G R R V+ G + +GF S+R
Sbjct: 648 DGQQLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQSER 707
Query: 245 ELGLWDPNNFEE-PVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFV 303
+L L++ P+A+ +D + LLP YDPD+ +V L GKGD+ + +E+ E PF
Sbjct: 708 QLLLYEAEALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLPESPFF 767
Query: 304 HYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPR-KSDLFQDDL 362
N+F+S +P +G+ +PK DV + E+ R +L + EP+ +PR + + FQDD+
Sbjct: 768 LECNSFTSPDPHKGLVLLPKTECDVREVELMRCLRLRQSSLEPVAFRLPRVRKEFFQDDV 827
Query: 363 YPDTPGP-EPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRR 421
+PDT EP L A+ WL G + +P L+SL+ PP + R R PS +
Sbjct: 828 FPDTAVIWEPVLSAEAWLQGANGQPWLLSLQ----PPDMSPVSQAPREAPARRAPSSAQY 883
Query: 422 SQSASD 427
+ SD
Sbjct: 884 LEEKSD 889
Score = 201 bits (510), Expect = 2e-51
Identities = 123/393 (31%), Positives = 196/393 (49%), Gaps = 8/393 (2%)
Query: 7 RQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAK 66
R SKFRH + + + DIR T S + I + G ++PL
Sbjct: 5 RVSKFRHTEARPPRRESWISDIRAG--TAPSCRNHIKSSCSLIAFNSDRPGVLGIVPLQG 62
Query: 67 TGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNI-TEPII 125
G + + H+ V D+D+ P +D ++A+ S D T+ +W++P P + + + P +
Sbjct: 63 QGEDKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPG--PGQALPSAPGV 120
Query: 126 TLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNS 185
L V +L +HPT+ +L+SA G V + W+ + L L H D++ S W+
Sbjct: 121 VLGPEDLPVEVLQFHPTSDGILVSAAGTTVKV-WDAAKQQPLTELA-AHGDLVQSAVWSR 178
Query: 186 NGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQG-HIFTTGFTRMSQR 244
+G+L+ T CKDK LRI DPR ++ AHE R R + H+ +TGF +M +R
Sbjct: 179 DGALVGTACKDKQLRIFDPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGFNQMRER 238
Query: 245 ELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVH 304
E+ LWD F +A +DTS G L+P DPDS ++ L GKG+ + +E+ + P +
Sbjct: 239 EVKLWDTRFFSSALASLTLDTSLGCLVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALS 298
Query: 305 YLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYP 364
+ + RG +P++ L V CE+ R +L + PI VPRK+ F +DL+P
Sbjct: 299 PVTQCVLESVLRGAALVPRQALAVMSCEVLRVLQLSDTAIVPIGYHVPRKAVEFHEDLFP 358
Query: 365 DTPGPEPALEADEWLSGQDAEPVLISLRDGYVP 397
DT G PA + W +G + + +SL P
Sbjct: 359 DTAGCVPATDPHSWWAGDNQQVQKVSLNPACRP 391
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 75.1 bits (183), Expect = 1e-13
Identities = 51/188 (27%), Positives = 90/188 (47%), Gaps = 15/188 (7%)
Query: 66 KTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPII 125
K G+V + TGHTA V D+ W ++++ S +DD +M+W T N ++P
Sbjct: 177 KEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWD----TRSNNTSKPSH 232
Query: 126 TLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWN- 184
+++ H+ V LS++P + +L + D + +W++ ++ L + H D I V W+
Sbjct: 233 SVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSP 292
Query: 185 SNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQR 244
N ++LA++ D+ L + D K A +G P +F GH T + S
Sbjct: 293 HNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDG--PPELLFIHGGH--TAKISDFS-- 346
Query: 245 ELGLWDPN 252
W+PN
Sbjct: 347 ----WNPN 350
Score = 55.8 bits (133), Expect = 8e-08
Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILS 138
GH + W P+ + SASDD TI +W I + + GH+ V +S
Sbjct: 140 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVS 199
Query: 139 WHPTARNVLLSAGGDNVIIIWNV---GTGEVLLSLDDMHPDVIHSVCWNSNGS-LLATTC 194
WH ++ S D ++IW+ T + S+ D H ++ + +N +LAT
Sbjct: 200 WHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSV-DAHTAEVNCLSFNPYSEFILATGS 258
Query: 195 KDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQ--GHIFTTGFTRMSQRELGLWDPN 252
DKT+ + D R ++ F +H+ +F Q H T + + R L +WD +
Sbjct: 259 ADKTVALWDLRNLKLKLHSFESHKD-----EIFQVQWSPHNETILASSGTDRRLNVWDLS 313
Query: 253 NFEEPVALQEMDTSNGVLL 271
E + ++ + LL
Sbjct: 314 KIGEEQSPEDAEDGPPELL 332
Score = 49.7 bits (117), Expect = 6e-06
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 21/191 (10%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPI------ITLEGHSKR 133
H V + P N +IA+ + + ++V+ DYT + +P + L GH K
Sbjct: 88 HEGEVNRARYMPQNPCIIATKTPSSDVLVF---DYTKHPSKPDPSGECNPDLRLRGHQKE 144
Query: 134 VGILSWHPTARNVLLSAGGDNVIIIWNVGT----GEVL--LSLDDMHPDVIHSVCWN-SN 186
LSW+P LLSA D+ I +W++ G+V+ ++ H V+ V W+ +
Sbjct: 145 GYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLH 204
Query: 187 GSLLATTCKDKTLRIIDPRKGQV--VAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQR 244
SL + D+ L I D R + AH + I TG + +
Sbjct: 205 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATG---SADK 261
Query: 245 ELGLWDPNNFE 255
+ LWD N +
Sbjct: 262 TVALWDLRNLK 272
Score = 48.5 bits (114), Expect = 1e-05
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNIT-------EPIITLEGHSK 132
H + + W PHN+ ++AS+ D + VW + ++ E + GH+
Sbjct: 281 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 340
Query: 133 RVGILSWHPTARNVLLSAGGDNVIIIWNV 161
++ SW+P V+ S DN++ +W +
Sbjct: 341 KISDFSWNPNEPWVICSVSEDNIMQVWQM 369
Score = 37.7 bits (86), Expect = 0.023
Identities = 15/35 (42%), Positives = 21/35 (60%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPD 113
GHTA + D W P+ VI S S+D + VWQ+ +
Sbjct: 337 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAE 371
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 75.1 bits (183), Expect = 1e-13
Identities = 51/188 (27%), Positives = 90/188 (47%), Gaps = 15/188 (7%)
Query: 66 KTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPII 125
K G+V + TGHTA V D+ W ++++ S +DD +M+W T N ++P
Sbjct: 211 KEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWD----TRSNNTSKPSH 266
Query: 126 TLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWN- 184
+++ H+ V LS++P + +L + D + +W++ ++ L + H D I V W+
Sbjct: 267 SVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSP 326
Query: 185 SNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQR 244
N ++LA++ D+ L + D K A +G P +F GH T + S
Sbjct: 327 HNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDG--PPELLFIHGGH--TAKISDFS-- 380
Query: 245 ELGLWDPN 252
W+PN
Sbjct: 381 ----WNPN 384
Score = 55.8 bits (133), Expect = 8e-08
Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILS 138
GH + W P+ + SASDD TI +W I + + GH+ V +S
Sbjct: 174 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVS 233
Query: 139 WHPTARNVLLSAGGDNVIIIWNV---GTGEVLLSLDDMHPDVIHSVCWNSNGS-LLATTC 194
WH ++ S D ++IW+ T + S+ D H ++ + +N +LAT
Sbjct: 234 WHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSV-DAHTAEVNCLSFNPYSEFILATGS 292
Query: 195 KDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQ--GHIFTTGFTRMSQRELGLWDPN 252
DKT+ + D R ++ F +H+ +F Q H T + + R L +WD +
Sbjct: 293 ADKTVALWDLRNLKLKLHSFESHKD-----EIFQVQWSPHNETILASSGTDRRLNVWDLS 347
Query: 253 NFEEPVALQEMDTSNGVLL 271
E + ++ + LL
Sbjct: 348 KIGEEQSPEDAEDGPPELL 366
Score = 49.7 bits (117), Expect = 6e-06
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 21/191 (10%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPI------ITLEGHSKR 133
H V + P N +IA+ + + ++V+ DYT + +P + L GH K
Sbjct: 122 HEGEVNRARYMPQNPCIIATKTPSSDVLVF---DYTKHPSKPDPSGECNPDLRLRGHQKE 178
Query: 134 VGILSWHPTARNVLLSAGGDNVIIIWNVGT----GEVL--LSLDDMHPDVIHSVCWN-SN 186
LSW+P LLSA D+ I +W++ G+V+ ++ H V+ V W+ +
Sbjct: 179 GYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLH 238
Query: 187 GSLLATTCKDKTLRIIDPRKGQV--VAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQR 244
SL + D+ L I D R + AH + I TG + +
Sbjct: 239 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATG---SADK 295
Query: 245 ELGLWDPNNFE 255
+ LWD N +
Sbjct: 296 TVALWDLRNLK 306
Score = 48.5 bits (114), Expect = 1e-05
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNIT-------EPIITLEGHSK 132
H + + W PHN+ ++AS+ D + VW + ++ E + GH+
Sbjct: 315 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 374
Query: 133 RVGILSWHPTARNVLLSAGGDNVIIIWNV 161
++ SW+P V+ S DN++ +W +
Sbjct: 375 KISDFSWNPNEPWVICSVSEDNIMQVWQM 403
Score = 37.7 bits (86), Expect = 0.023
Identities = 15/35 (42%), Positives = 21/35 (60%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPD 113
GHTA + D W P+ VI S S+D + VWQ+ +
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAE 405
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 75.1 bits (183), Expect = 1e-13
Identities = 51/188 (27%), Positives = 90/188 (47%), Gaps = 15/188 (7%)
Query: 66 KTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPII 125
K G+V + TGHTA V D+ W ++++ S +DD +M+W T N ++P
Sbjct: 212 KEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWD----TRSNNTSKPSH 267
Query: 126 TLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWN- 184
+++ H+ V LS++P + +L + D + +W++ ++ L + H D I V W+
Sbjct: 268 SVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSP 327
Query: 185 SNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQR 244
N ++LA++ D+ L + D K A +G P +F GH T + S
Sbjct: 328 HNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDG--PPELLFIHGGH--TAKISDFS-- 381
Query: 245 ELGLWDPN 252
W+PN
Sbjct: 382 ----WNPN 385
Score = 55.8 bits (133), Expect = 8e-08
Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILS 138
GH + W P+ + SASDD TI +W I + + GH+ V +S
Sbjct: 175 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVS 234
Query: 139 WHPTARNVLLSAGGDNVIIIWNV---GTGEVLLSLDDMHPDVIHSVCWNSNGS-LLATTC 194
WH ++ S D ++IW+ T + S+ D H ++ + +N +LAT
Sbjct: 235 WHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSV-DAHTAEVNCLSFNPYSEFILATGS 293
Query: 195 KDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQ--GHIFTTGFTRMSQRELGLWDPN 252
DKT+ + D R ++ F +H+ +F Q H T + + R L +WD +
Sbjct: 294 ADKTVALWDLRNLKLKLHSFESHKD-----EIFQVQWSPHNETILASSGTDRRLNVWDLS 348
Query: 253 NFEEPVALQEMDTSNGVLL 271
E + ++ + LL
Sbjct: 349 KIGEEQSPEDAEDGPPELL 367
Score = 49.7 bits (117), Expect = 6e-06
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 21/191 (10%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPI------ITLEGHSKR 133
H V + P N +IA+ + + ++V+ DYT + +P + L GH K
Sbjct: 123 HEGEVNRARYMPQNPCIIATKTPSSDVLVF---DYTKHPSKPDPSGECNPDLRLRGHQKE 179
Query: 134 VGILSWHPTARNVLLSAGGDNVIIIWNVGT----GEVL--LSLDDMHPDVIHSVCWN-SN 186
LSW+P LLSA D+ I +W++ G+V+ ++ H V+ V W+ +
Sbjct: 180 GYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLH 239
Query: 187 GSLLATTCKDKTLRIIDPRKGQV--VAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQR 244
SL + D+ L I D R + AH + I TG + +
Sbjct: 240 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATG---SADK 296
Query: 245 ELGLWDPNNFE 255
+ LWD N +
Sbjct: 297 TVALWDLRNLK 307
Score = 48.5 bits (114), Expect = 1e-05
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNIT-------EPIITLEGHSK 132
H + + W PHN+ ++AS+ D + VW + ++ E + GH+
Sbjct: 316 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 375
Query: 133 RVGILSWHPTARNVLLSAGGDNVIIIWNV 161
++ SW+P V+ S DN++ +W +
Sbjct: 376 KISDFSWNPNEPWVICSVSEDNIMQVWQM 404
Score = 37.7 bits (86), Expect = 0.023
Identities = 15/35 (42%), Positives = 21/35 (60%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPD 113
GHTA + D W P+ VI S S+D + VWQ+ +
Sbjct: 372 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAE 406
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 70.9 bits (172), Expect = 2e-12
Identities = 48/188 (25%), Positives = 89/188 (47%), Gaps = 15/188 (7%)
Query: 66 KTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPII 125
K G++ + TGH+A V D+ W ++++ S +DD +M+W T ++P
Sbjct: 211 KEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWD----TRSNTTSKPSH 266
Query: 126 TLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWN- 184
++ H+ V LS++P + +L + D + +W++ ++ L + H D I V W+
Sbjct: 267 LVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSP 326
Query: 185 SNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQR 244
N ++LA++ D+ L + D K + E+ A P +F GH T + S
Sbjct: 327 HNETILASSGTDRRLNVWDLSK--IGEEQSAEDAEDGPPELLFIHGGH--TAKISDFS-- 380
Query: 245 ELGLWDPN 252
W+PN
Sbjct: 381 ----WNPN 384
Score = 52.4 bits (124), Expect = 9e-07
Identities = 47/198 (23%), Positives = 80/198 (40%), Gaps = 10/198 (5%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILS 138
GH + W + + SASDD T+ +W I I + GHS V ++
Sbjct: 174 GHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVA 233
Query: 139 WHPTARNVLLSAGGDNVIIIWNV--GTGEVLLSLDDMHPDVIHSVCWNSNGS-LLATTCK 195
WH ++ S D ++IW+ T L D H ++ + +N +LAT
Sbjct: 234 WHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSA 293
Query: 196 DKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFT--RQGHIFTTGFTRMSQRELGLWDPNN 253
DKT+ + D R ++ F +H+ +F H T + + R L +WD +
Sbjct: 294 DKTVALWDLRNLKLKLHTFESHKD-----EIFQVHWSPHNETILASSGTDRRLNVWDLSK 348
Query: 254 FEEPVALQEMDTSNGVLL 271
E + ++ + LL
Sbjct: 349 IGEEQSAEDAEDGPPELL 366
Score = 49.3 bits (116), Expect = 8e-06
Identities = 40/152 (26%), Positives = 67/152 (44%), Gaps = 18/152 (11%)
Query: 67 TGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYT--PMR----NI 120
TG+++ + H V + P N ++IA+ + + ++V+ DYT P +
Sbjct: 111 TGKIECEIKI--NHEGEVNRARYMPQNPHIIATKTPSSDVLVF---DYTKHPAKPDPSGE 165
Query: 121 TEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDM------H 174
P + L GH K LSW+ LLSA D+ + +W++ G + D H
Sbjct: 166 CNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGH 225
Query: 175 PDVIHSVCWN-SNGSLLATTCKDKTLRIIDPR 205
V+ V W+ + SL + D+ L I D R
Sbjct: 226 SAVVEDVAWHLLHESLFGSVADDQKLMIWDTR 257
Score = 49.3 bits (116), Expect = 8e-06
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNIT-------EPIITLEGHSK 132
H + + W PHN+ ++AS+ D + VW + ++ E + GH+
Sbjct: 315 HKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTA 374
Query: 133 RVGILSWHPTARNVLLSAGGDNVIIIWNV 161
++ SW+P V+ S DN++ IW +
Sbjct: 375 KISDFSWNPNEPWVICSVSEDNIMQIWQM 403
Score = 37.4 bits (85), Expect = 0.030
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPD 113
GHTA + D W P+ VI S S+D + +WQ+ +
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAE 405
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 69.7 bits (169), Expect = 5e-12
Identities = 62/239 (25%), Positives = 105/239 (43%), Gaps = 29/239 (12%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSW 139
HT V D+ + P ++ SAS D T+ VW + D M + L GH V ++
Sbjct: 169 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKV------LRGHQNWVYSCAF 222
Query: 140 HPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTL 199
P + ++L S G + +WN+ ++ L+ H DV+ + ++ +G+LLAT D +
Sbjct: 223 SPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVV-ACDFSPDGALLATASYDTRV 280
Query: 200 RIIDPRKGQVVAE----------RFAAHEGMRPMRAV-FTRQG-HIFTTGFTRMSQRELG 247
I DP G ++ E FA R +R+V F+ G H+ + +M +
Sbjct: 281 YIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKM----VR 336
Query: 248 LWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYL 306
W +E +Q SNG+ F S V G D S+ ++ + P + +L
Sbjct: 337 FW---RIDEDYPVQVAPLSNGLCCAFSTDGS--VLAAGTHDGSVYFWATPRQVPSLQHL 390
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 10/99 (10%)
Query: 107 MVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVII-IWNVGTGE 165
+VW + + + + +E H R G +LL+ G +N I IW+V TG+
Sbjct: 109 IVWSLAFGSSVPEKQSRCVNIEWHRFRFG-------QDQLLLATGLNNGRIKIWDVYTGK 161
Query: 166 VLLSLDDMHPDVIHSVCWNSNGSL-LATTCKDKTLRIID 203
+LL+L D H +V+ + + +GSL L + +DKTLR+ D
Sbjct: 162 LLLNLVD-HTEVVRDLTFAPDGSLILVSASRDKTLRVWD 199
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 69.7 bits (169), Expect = 5e-12
Identities = 62/239 (25%), Positives = 105/239 (43%), Gaps = 29/239 (12%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSW 139
HT V D+ + P ++ SAS D T+ VW + D M + L GH V ++
Sbjct: 23 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKV------LRGHQNWVYSCAF 76
Query: 140 HPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTL 199
P + ++L S G + +WN+ ++ L+ H DV+ + ++ +G+LLAT D +
Sbjct: 77 SPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVV-ACDFSPDGALLATASYDTRV 134
Query: 200 RIIDPRKGQVVAE----------RFAAHEGMRPMRAV-FTRQG-HIFTTGFTRMSQRELG 247
I DP G ++ E FA R +R+V F+ G H+ + +M +
Sbjct: 135 YIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKM----VR 190
Query: 248 LWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYL 306
W +E +Q SNG+ F S V G D S+ ++ + P + +L
Sbjct: 191 FW---RIDEDYPVQVAPLSNGLCCAFSTDGS--VLAAGTHDGSVYFWATPRQVPSLQHL 244
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 67.4 bits (163), Expect = 3e-11
Identities = 45/149 (30%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 60 IVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRN 119
I++ A G+ +K + GH + D+ W + ++ SASDD T+ +W + ++
Sbjct: 65 IIIWGAYDGKYEKT---LYGHNLEISDVAWSSDSSRLV-SASDDKTLKLWDVRSGKCLK- 119
Query: 120 ITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIH 179
TL+GHS V +++P + N+++S D + IW V TG+ L +L H D +
Sbjct: 120 ------TLKGHSNYVFCCNFNPPS-NLIISGSFDETVKIWEVKTGKCLKTL-SAHSDPVS 171
Query: 180 SVCWNSNGSLLATTCKDKTLRIIDPRKGQ 208
+V +N +GSL+ + D RI D GQ
Sbjct: 172 AVHFNCSGSLIVSGSYDGLCRIWDAASGQ 200
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/140 (25%), Positives = 68/140 (48%), Gaps = 9/140 (6%)
Query: 69 RVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLE 128
R K + GH+ V ++ P + N+I S S D T+ +W++ ++ TL
Sbjct: 113 RSGKCLKTLKGHSNYVFCCNFNPPS-NLIISGSFDETVKIWEVKTGKCLK-------TLS 164
Query: 129 GHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGS 188
HS V + ++ + ++++S D + IW+ +G+ L +L D + V ++ NG
Sbjct: 165 AHSDPVSAVHFNCSG-SLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGK 223
Query: 189 LLATTCKDKTLRIIDPRKGQ 208
+ T D TL++ D +G+
Sbjct: 224 YILTATLDNTLKLWDYSRGR 243
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 21/161 (13%)
Query: 126 TLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNS 185
TL GH++ V + + P L S+ D +IIIW G+ +L H I V W+S
Sbjct: 36 TLVGHTEAVSSVKFSPNGE-WLASSSADRLIIIWGAYDGKYEKTLYG-HNLEISDVAWSS 93
Query: 186 NGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQRE 245
+ S L + DKTL++ D R G+ ++ + ++F F S
Sbjct: 94 DSSRLVSASDDKTLKLWDVRSGKC-------------LKTLKGHSNYVFCCNFNPPS--- 137
Query: 246 LGLWDPNNFEEPVALQEMDTSN--GVLLPFYDPDSSIVYLC 284
L +F+E V + E+ T L DP S++ + C
Sbjct: 138 -NLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNC 177
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 13/130 (10%)
Query: 76 LVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHS--KR 133
LV PV + + P N I +A+ D T+ +W DY+ R + T GH K
Sbjct: 205 LVDDDNPPVSFVKFSP-NGKYILTATLDNTLKLW---DYSRGRCLK----TYTGHKNEKY 256
Query: 134 VGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATT 193
++ T ++S DN++ IWN+ T E++ L H DV+ S + +L+A+
Sbjct: 257 CIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVISAACHPTENLIASA 315
Query: 194 C--KDKTLRI 201
DKT+++
Sbjct: 316 ALENDKTIKL 325
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 66.2 bits (160), Expect = 6e-11
Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 13/149 (8%)
Query: 71 DKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGH 130
D+ + +GHTA V + W P + ++ S SDD T+ +W DYT I L GH
Sbjct: 532 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIW---DYTQDACIN----ILNGH 584
Query: 131 SKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLL 190
+ V L W+ +L+S D I +W+ G + ++ D DV C S +
Sbjct: 585 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTM 644
Query: 191 ATTCKDKTLR------IIDPRKGQVVAER 213
A+ +D T+R ++ P + ++A+R
Sbjct: 645 ASCSRDSTVRLWSLTALVTPVQINILADR 673
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILS 138
GH + D + P + N++A+AS D TI VW I N + T G+ + LS
Sbjct: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI-------NTLTAVYTSPGNEGVIYSLS 419
Query: 139 WHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKT 198
W P N + N IWNV G+++ ++ + I + W+ S TC
Sbjct: 420 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDG 479
Query: 199 LRIIDPRKGQVV 210
II G+V+
Sbjct: 480 FCIIRTIDGKVL 491
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 7/132 (5%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSW 139
H A V DW +N ++IA+ +DT + V+ + + +P+ GH+ +V + W
Sbjct: 496 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYV-----ATSSDQPLKVFSGHTAKVFHVKW 550
Query: 140 HPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSN-GSLLATTCKDKT 198
P +L S D + IW+ T + +++ + H + + WN+ LL + D T
Sbjct: 551 SPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYT 609
Query: 199 LRIIDPRKGQVV 210
+++ D R+G V
Sbjct: 610 IKVWDTREGTCV 621
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 72 KNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHS 131
K + +++ H + I WCPHN ++ AS S D +++W + + + I L+
Sbjct: 50 KLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE-------QKVIAKLDSTK 102
Query: 132 KRVGILSWHPTARNVLLSAGGDNVIIIWNV 161
LSW A +V+ + IW +
Sbjct: 103 GIPASLSWCWNAEDVVAFVSHRGPLFIWTI 132
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 130 HSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHP-DVIHSVCWNS 185
H K + +SW P ++ S DN++IIWNV +V+ LD S CWN+
Sbjct: 58 HKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNA 114
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 66.2 bits (160), Expect = 6e-11
Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 13/149 (8%)
Query: 71 DKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGH 130
D+ + +GHTA V + W P + ++ S SDD T+ +W DYT I L GH
Sbjct: 556 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIW---DYTQDACIN----ILNGH 608
Query: 131 SKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLL 190
+ V L W+ +L+S D I +W+ G + ++ D DV C S +
Sbjct: 609 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTM 668
Query: 191 ATTCKDKTLR------IIDPRKGQVVAER 213
A+ +D T+R ++ P + ++A+R
Sbjct: 669 ASCSRDSTVRLWSLTALVTPVQINILADR 697
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILS 138
GH + D + P + N++A+AS D TI VW I N + T G+ + LS
Sbjct: 391 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI-------NTLTAVYTSPGNEGVIYSLS 443
Query: 139 WHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKT 198
W P N + N IWNV G+++ ++ + I + W+ S TC
Sbjct: 444 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDG 503
Query: 199 LRIIDPRKGQVV 210
II G+V+
Sbjct: 504 FCIIRTIDGKVL 515
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 7/132 (5%)
Query: 80 HTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSW 139
H A V DW +N ++IA+ +DT + V+ + + +P+ GH+ +V + W
Sbjct: 520 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYV-----ATSSDQPLKVFSGHTAKVFHVKW 574
Query: 140 HPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSN-GSLLATTCKDKT 198
P +L S D + IW+ T + +++ + H + + WN+ LL + D T
Sbjct: 575 SPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYT 633
Query: 199 LRIIDPRKGQVV 210
+++ D R+G V
Sbjct: 634 IKVWDTREGTCV 645
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 72 KNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHS 131
K + +++ H + I WCPHN ++ AS S D +++W + + + I L+
Sbjct: 74 KLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE-------QKVIAKLDSTK 126
Query: 132 KRVGILSWHPTARNVLLSAGGDNVIIIWNV 161
LSW A +V+ + IW +
Sbjct: 127 GIPASLSWCWNAEDVVAFVSHRGPLFIWTI 156
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 130 HSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHP-DVIHSVCWNS 185
H K + +SW P ++ S DN++IIWNV +V+ LD S CWN+
Sbjct: 82 HKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNA 138
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 66.2 bits (160), Expect = 6e-11
Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 6/98 (6%)
Query: 97 IASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNV- 155
+A+ S DTT+++WQ+ P ++ + + TLEGH+ V ++W P N L++ G D+
Sbjct: 207 LATGSKDTTVIIWQVD---PDTHLLKLLKTLEGHAYGVSYIAWSPDD-NYLVACGPDDCS 262
Query: 156 -IIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLAT 192
+ +WNV TGE+ + H D + SV WN +G T
Sbjct: 263 ELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVT 300
Score = 48.1 bits (113), Expect = 2e-05
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 7/68 (10%)
Query: 92 HNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAG 151
HN++ IAS S+D + +W + PI L GH++ V +SW+P +++ SA
Sbjct: 418 HNEDFIASGSEDHKVYIWH-------KRSELPIAELTGHTRTVNCVSWNPQIPSMMASAS 470
Query: 152 GDNVIIIW 159
D + IW
Sbjct: 471 DDGTVRIW 478
Score = 40.4 bits (93), Expect = 0.004
Identities = 18/52 (34%), Positives = 30/52 (57%)
Query: 77 VTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLE 128
+TGHT V + W P +++ASASDD T+ +W + +NI E +++
Sbjct: 446 LTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWGPAPFIDHQNIEEECSSMD 497
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 66.2 bits (160), Expect = 6e-11
Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 6/98 (6%)
Query: 97 IASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNV- 155
+A+ S DTT+++WQ+ P ++ + + TLEGH+ V ++W P N L++ G D+
Sbjct: 223 LATGSKDTTVIIWQVD---PDTHLLKLLKTLEGHAYGVSYIAWSPDD-NYLVACGPDDCS 278
Query: 156 -IIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLAT 192
+ +WNV TGE+ + H D + SV WN +G T
Sbjct: 279 ELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVT 316
Score = 48.1 bits (113), Expect = 2e-05
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 7/68 (10%)
Query: 92 HNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAG 151
HN++ IAS S+D + +W + PI L GH++ V +SW+P +++ SA
Sbjct: 434 HNEDFIASGSEDHKVYIWH-------KRSELPIAELTGHTRTVNCVSWNPQIPSMMASAS 486
Query: 152 GDNVIIIW 159
D + IW
Sbjct: 487 DDGTVRIW 494
Score = 40.4 bits (93), Expect = 0.004
Identities = 18/52 (34%), Positives = 30/52 (57%)
Query: 77 VTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLE 128
+TGHT V + W P +++ASASDD T+ +W + +NI E +++
Sbjct: 462 LTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWGPAPFIDHQNIEEECSSMD 513
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 64.3 bits (155), Expect = 2e-10
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 76 LVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVG 135
++ H A +L DWC +N+N++ + + D ++ W + RN+ +P+ L GH+ +
Sbjct: 193 VIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDL------RNVRQPVFELLGHTYAIR 246
Query: 136 ILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCK 195
+ + P +VL S D + WN + LL + H + + ++ C
Sbjct: 247 RVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCS 306
Query: 196 -DKTLRIIDP 204
D+T++I DP
Sbjct: 307 WDETIKIYDP 316
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/271 (19%), Positives = 109/271 (40%), Gaps = 20/271 (7%)
Query: 84 VLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPT- 142
+ D+ W +N++V+ + S D ++ +W P+ + H++ V + W T
Sbjct: 70 LFDVTWSENNEHVLITCSGDGSLQLWD------TAKAAGPLQVYKEHAQEVYSVDWSQTR 123
Query: 143 ARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSN-GSLLATTCKDKTLRI 201
+++S D + +W+ G+ L + H +I+S W+ + A+ D+TLRI
Sbjct: 124 GEQLVVSGSWDQTVKLWDPTVGKSLCTFRG-HESIIYSTIWSPHIPGCFASASGDQTLRI 182
Query: 202 IDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQRELGLWDPNNFEEPVALQ 261
D K V AH+ ++ TG S R WD N +PV +
Sbjct: 183 WDV-KAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRG---WDLRNVRQPV-FE 237
Query: 262 EMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFM 321
+ + + + P + V D ++R++ + + + + E G+ F
Sbjct: 238 LLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHT--EFTCGLDFS 295
Query: 322 PKRGLDVSKCEIARFYKLHERKCEPIIMTVP 352
+ V+ C K+++ C +T+P
Sbjct: 296 LQSPTQVADCSWDETIKIYDPAC----LTIP 322
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/158 (22%), Positives = 61/158 (38%), Gaps = 11/158 (6%)
Query: 49 IIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCP-HNDNVIASASDDTTIM 107
+++ G G+ L L T + + H V +DW + ++ S S D T+
Sbjct: 82 VLITCSGDGS---LQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVK 138
Query: 108 VWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVL 167
+W + + + T GH + W P SA GD + IW+V V
Sbjct: 139 LWD-------PTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVR 191
Query: 168 LSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPR 205
+ + +++ N +LL T D +LR D R
Sbjct: 192 IVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLR 229
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 62.8 bits (151), Expect = 7e-10
Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 17/148 (11%)
Query: 71 DKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGH 130
D+ GHT V I W P N++AS SDD T+ +W + + + L+ H
Sbjct: 339 DRPIKTFQGHTNEVNAIKWDP-TGNLLASCSDDMTLKIWSMKQDNCVHD-------LQAH 390
Query: 131 SKRVGILSWHPT--------ARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
+K + + W PT A +L SA D+ + +W+V G + +L H + ++SV
Sbjct: 391 NKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL-TKHQEPVYSVA 449
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVV 210
++ +G LA+ DK + I + + G +V
Sbjct: 450 FSPDGRYLASGSFDKCVHIWNTQTGALV 477
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/135 (30%), Positives = 63/135 (46%), Gaps = 18/135 (13%)
Query: 80 HTAPVLDIDWCP-----HNDN---VIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHS 131
H + I W P +N N ++ASAS D+T+ +W + R I I TL H
Sbjct: 390 HNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVD-----RGIC--IHTLTKHQ 442
Query: 132 KRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLA 191
+ V +++ P R L S D + IWN TG ++ S I VCWN+ G +
Sbjct: 443 EPVYSVAFSPDGR-YLASGSFDKCVHIWNTQTGALVHSYRGTGG--IFEVCWNAAGDKVG 499
Query: 192 TTCKDKTLRIIDPRK 206
+ D ++ ++D RK
Sbjct: 500 ASASDGSVCVLDLRK 514
Score = 42.7 bits (99), Expect = 7e-04
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 14/90 (15%)
Query: 125 ITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNV------GTGEVLLS--LDDMHPD 176
+ L GH V I +W+P + ++L S GD+ IWN+ G+ +++L + + D
Sbjct: 163 VVLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQD 221
Query: 177 V-----IHSVCWNSNGSLLATTCKDKTLRI 201
V + S+ WNS G+LLAT D RI
Sbjct: 222 VPSNKDVTSLDWNSEGTLLATGSYDGFARI 251
Score = 40.4 bits (93), Expect = 0.004
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 16/151 (10%)
Query: 76 LVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIIT---LEG--- 129
++ GH + V W P +D ++AS S D+T +W + + + + T+ ++ EG
Sbjct: 164 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLSENSTSGS-TQLVLRHCIREGGQD 221
Query: 130 --HSKRVGILSWHPTARNVLLSAGG-DNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSN 186
+K V L W+ + LL+ G D IW L S H I ++ WN
Sbjct: 222 VPSNKDVTSLDWN--SEGTLLATGSYDGFARIWTKDGN--LASTLGQHKGPIFALKWNKK 277
Query: 187 GSLLATTCKDKTLRIIDPRKGQVVAERFAAH 217
G+ + + DKT I D G+ ++F H
Sbjct: 278 GNFILSAGVDKTTIIWDAHTGE-AKQQFPFH 307
Score = 37.0 bits (84), Expect = 0.039
Identities = 40/158 (25%), Positives = 60/158 (37%), Gaps = 50/158 (31%)
Query: 84 VLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTA 143
V +DW ++A+ S D +W T N+ TL H + L W+
Sbjct: 228 VTSLDWNSEG-TLLATGSYDGFARIW-----TKDGNLAS---TLGQHKGPIFALKWNKKG 278
Query: 144 RNVLLSAGGDNVIIIWNVGTGEV----------LLSLD------------DM-------- 173
N +LSAG D IIW+ TGE L +D DM
Sbjct: 279 -NFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLG 337
Query: 174 ----------HPDVIHSVCWNSNGSLLATTCKDKTLRI 201
H + ++++ W+ G+LLA+ D TL+I
Sbjct: 338 QDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKI 375
>gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens]
Length = 559
Score = 61.2 bits (147), Expect = 2e-09
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 51 VEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQ 110
VE G G IV L+ R HT V + + P + ++AS DD I++W+
Sbjct: 46 VEKGPDGKAIVEFLSNLAR----------HTKAVNVVRFSPTGE-ILASGGDDAVILLWK 94
Query: 111 IPDYTPMRNIT--------------EPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVI 156
+ D I + TL GH + V + W T N++ SA DN
Sbjct: 95 VNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICW-ATDGNLMASASVDNTA 153
Query: 157 IIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQV 209
IIW+V G+ + S+ + H + V W+ G +AT D+ LR+ +K +V
Sbjct: 154 IIWDVSKGQKI-SIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSIQKKRV 205
Score = 60.5 bits (145), Expect = 3e-09
Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 21/135 (15%)
Query: 97 IASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVI 156
+ASA DT + +W++ + I E + L H+K V ++ + PT +L S G D VI
Sbjct: 32 LASAGVDTNVRIWKVEKGPDGKAIVEFLSNLARHTKAVNVVRFSPTGE-ILASGGDDAVI 90
Query: 157 IIWNVGTG------------EVLLSLDDM--------HPDVIHSVCWNSNGSLLATTCKD 196
++W V E L+ ++ H + ++ +CW ++G+L+A+ D
Sbjct: 91 LLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMASASVD 150
Query: 197 KTLRIIDPRKGQVVA 211
T I D KGQ ++
Sbjct: 151 NTAIIWDVSKGQKIS 165
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 16/158 (10%)
Query: 96 VIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNV 155
+I SASDD T+ +W ++ E + + H V + +HP+ + +AG DN
Sbjct: 121 LIVSASDDKTVKLWD-------KSSRECVHSYCEHGGFVTYVDFHPSG-TCIAAAGMDNT 172
Query: 156 IIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFA 215
+ +W+V T LL +H ++ + ++ +G+ L T D TL+I+D +G+++ +
Sbjct: 173 VKVWDVRTHR-LLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL---YT 228
Query: 216 AHEGMRPMRAV-FTRQGHIFTTGFTRMSQRELGLWDPN 252
H P V F+R G F +G S ++ +W N
Sbjct: 229 LHGHQGPATTVAFSRTGEYFASG---GSDEQVMVWKSN 263
Score = 36.2 bits (82), Expect = 0.066
Identities = 81/394 (20%), Positives = 150/394 (38%), Gaps = 64/394 (16%)
Query: 103 DTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIW--N 160
D+ +MVW + + T GH V +++ P+ ++L S D + IW N
Sbjct: 2 DSCLMVWHMKPQSRAYRFT-------GHKDAVTCVNFSPSG-HLLASGSRDKTVRIWVPN 53
Query: 161 V-GTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEG 219
V G V + H + SV + S+G T DKT+++ + + + F+ +
Sbjct: 54 VKGESTVFRA----HTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFL---FSLSQH 106
Query: 220 MRPMR-AVFTRQGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYD--P 276
+ +R A F+ G + + + + LWD ++ E + E +G + + D P
Sbjct: 107 INWVRCAKFSPDGRLIVSA---SDDKTVKLWDKSSRECVHSYCE----HGGFVTYVDFHP 159
Query: 277 DSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSK------ 330
+ + G D++++ +++ HY G+ F P ++
Sbjct: 160 SGTCIAAAGM-DNTVKVWDVRTHRLLQHYQ---LHSAAVNGLSFHPSGNYLITASSDSTL 215
Query: 331 -----CEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAE 385
E Y LH + + R + F + G + + W S D
Sbjct: 216 KILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA------SGGSDEQVMV--WKSNFD-- 265
Query: 386 PVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRS------QSASDAPLSQQHTLETL 439
++ VP L + N+ +V P P R QS P+S TL +
Sbjct: 266 -IVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTST 324
Query: 440 LE----EIKALRERVQAQEQRITALENMLCELVD 469
LE ++ L + V EQR+T E+ L + ++
Sbjct: 325 LEHIVGQLDVLTQTVSILEQRLTLTEDKLKQCLE 358
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 16/158 (10%)
Query: 96 VIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNV 155
+I SASDD T+ +W ++ E + + H V + +HP+ + +AG DN
Sbjct: 159 LIVSASDDKTVKLWD-------KSSRECVHSYCEHGGFVTYVDFHPSG-TCIAAAGMDNT 210
Query: 156 IIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFA 215
+ +W+V T LL +H ++ + ++ +G+ L T D TL+I+D +G+++ +
Sbjct: 211 VKVWDVRTHR-LLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL---YT 266
Query: 216 AHEGMRPMRAV-FTRQGHIFTTGFTRMSQRELGLWDPN 252
H P V F+R G F +G S ++ +W N
Sbjct: 267 LHGHQGPATTVAFSRTGEYFASG---GSDEQVMVWKSN 301
Score = 40.0 bits (92), Expect = 0.005
Identities = 54/249 (21%), Positives = 108/249 (43%), Gaps = 33/249 (13%)
Query: 63 PLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITE 122
P A+ +++++ GH V +D+ N +AS S D+ +MVW + + T
Sbjct: 4 PCAEDPSLERHFK---GHRDAVTCVDFSI-NTKQLASGSMDSCLMVWHMKPQSRAYRFT- 58
Query: 123 PIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIW--NV-GTGEVLLSLDDMHPDVIH 179
GH V +++ P+ ++L S D + IW NV G V + H +
Sbjct: 59 ------GHKDAVTCVNFSPSG-HLLASGSRDKTVRIWVPNVKGESTVFRA----HTATVR 107
Query: 180 SVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMR-AVFTRQGHIFTTGF 238
SV + S+G T DKT+++ + + + F+ + + +R A F+ G + +
Sbjct: 108 SVHFCSDGQSFVTASDDKTVKVWATHRQKFL---FSLSQHINWVRCAKFSPDGRLIVSA- 163
Query: 239 TRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYD--PDSSIVYLCGKGDSSIRYFEI 296
+ + LWD ++ E + E +G + + D P + + G D++++ +++
Sbjct: 164 --SDDKTVKLWDKSSRECVHSYCE----HGGFVTYVDFHPSGTCIAAAGM-DNTVKVWDV 216
Query: 297 TDEPPFVHY 305
HY
Sbjct: 217 RTHRLLQHY 225
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 16/158 (10%)
Query: 96 VIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNV 155
+I SASDD T+ +W ++ E + + H V + +HP+ + +AG DN
Sbjct: 159 LIVSASDDKTVKLWD-------KSSRECVHSYCEHGGFVTYVDFHPSG-TCIAAAGMDNT 210
Query: 156 IIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFA 215
+ +W+V T LL +H ++ + ++ +G+ L T D TL+I+D +G+++ +
Sbjct: 211 VKVWDVRTHR-LLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL---YT 266
Query: 216 AHEGMRPMRAV-FTRQGHIFTTGFTRMSQRELGLWDPN 252
H P V F+R G F +G S ++ +W N
Sbjct: 267 LHGHQGPATTVAFSRTGEYFASG---GSDEQVMVWKSN 301
Score = 43.5 bits (101), Expect = 4e-04
Identities = 91/434 (20%), Positives = 169/434 (38%), Gaps = 68/434 (15%)
Query: 63 PLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITE 122
P A+ +++++ GH V +D+ N +AS S D+ +MVW + + T
Sbjct: 4 PCAEDPSLERHFK---GHRDAVTCVDFSI-NTKQLASGSMDSCLMVWHMKPQSRAYRFT- 58
Query: 123 PIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIW--NV-GTGEVLLSLDDMHPDVIH 179
GH V +++ P+ ++L S D + IW NV G V + H +
Sbjct: 59 ------GHKDAVTCVNFSPSG-HLLASGSRDKTVRIWVPNVKGESTVFRA----HTATVR 107
Query: 180 SVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMR-AVFTRQGHIFTTGF 238
SV + S+G T DKT+++ + + + F+ + + +R A F+ G + +
Sbjct: 108 SVHFCSDGQSFVTASDDKTVKVWATHRQKFL---FSLSQHINWVRCAKFSPDGRLIVSA- 163
Query: 239 TRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYD--PDSSIVYLCGKGDSSIRYFEI 296
+ + LWD ++ E + E +G + + D P + + G D++++ +++
Sbjct: 164 --SDDKTVKLWDKSSRECVHSYCE----HGGFVTYVDFHPSGTCIAAAGM-DNTVKVWDV 216
Query: 297 TDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSK-----------CEIARFYKLHERKCE 345
HY G+ F P ++ E Y LH +
Sbjct: 217 RTHRLLQHYQ---LHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGP 273
Query: 346 PIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRV 405
+ R + F + G + + W S D ++ VP L
Sbjct: 274 ATTVAFSRTGEYFA------SGGSDEQVMV--WKSNFD---IVDHGEVTKVPRPPATLAS 322
Query: 406 TKRNILDVRPPSGPRRS------QSASDAPLSQQHTLETLLE----EIKALRERVQAQEQ 455
+ N+ +V P P R QS P+S TL + LE ++ L + V EQ
Sbjct: 323 SMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTSTLEHIVGQLDVLTQTVSILEQ 382
Query: 456 RITALENMLCELVD 469
R+T E+ L + ++
Sbjct: 383 RLTLTEDKLKQCLE 396
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 59.3 bits (142), Expect = 7e-09
Identities = 49/190 (25%), Positives = 77/190 (40%), Gaps = 15/190 (7%)
Query: 79 GHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILS 138
GH PV D + P+ + S D +W Y P+R GH V
Sbjct: 583 GHNYPVWDTQFSPYGYYFV-SGGHDRVARLWATDHYQPLR-------IFAGHLADVNCTR 634
Query: 139 WHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKT 198
+HP + N + + D + +W+V G + H IHS+ ++ NG LAT D
Sbjct: 635 FHPNS-NYVATGSADRTVRLWDVLNGNCVRIFTG-HKGPIHSLTFSPNGRFLATGATDGR 692
Query: 199 LRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQRELGLWDPNNFEEPV 258
+ + D G +V E + + +R F+R G I +G + R LWD E +
Sbjct: 693 VLLWDIGHGLMVGELKGHTDTVCSLR--FSRDGEILASGSMDNTVR---LWDAIKAFEDL 747
Query: 259 ALQEMDTSNG 268
+ T+ G
Sbjct: 748 ETDDFTTATG 757
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 59.3 bits (142), Expect = 7e-09
Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 17/148 (11%)
Query: 71 DKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGH 130
D+ GHT V I W P + ++AS SDD T+ +W + + + L+ H
Sbjct: 351 DRPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHD-------LQAH 402
Query: 131 SKRVGILSWHPTA-------RNVLL-SAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
+K + + W PT N++L SA D+ + +W++ G +L H + ++SV
Sbjct: 403 NKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL-TKHQEPVYSVA 461
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVV 210
++ +G LA+ DK + I + + G +V
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNTQSGNLV 489
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 18/135 (13%)
Query: 80 HTAPVLDIDWCPH-------NDNV-IASASDDTTIMVWQIPDYTPMRNITEPIITLEGHS 131
H + I W P N N+ +ASAS D+T+ +W I +T+ H
Sbjct: 402 HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQ 454
Query: 132 KRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLA 191
+ V +++ P + L S D + IWN +G ++ S I VCWN+ G +
Sbjct: 455 EPVYSVAFSPDGK-YLASGSFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVG 511
Query: 192 TTCKDKTLRIIDPRK 206
+ D ++ ++D RK
Sbjct: 512 ASASDGSVCVLDLRK 526
Score = 42.4 bits (98), Expect = 0.001
Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 14/88 (15%)
Query: 127 LEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNV------GTGEVLLS--LDDMHPDV- 177
L GH V I +W+P + ++L S GD+ IWN+ G+ +++L + + DV
Sbjct: 177 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 235
Query: 178 ----IHSVCWNSNGSLLATTCKDKTLRI 201
+ S+ WN+NG+LLAT D RI
Sbjct: 236 SNKDVTSLDWNTNGTLLATGSYDGFARI 263
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 76 LVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYT---PMRNITEPIITLEGH-- 130
++ GH + V W P +D ++AS S D+T +W + + + + + I GH
Sbjct: 176 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 131 --SKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGS 188
+K V L W+ T +L + D IW L S H I ++ WN G+
Sbjct: 235 PSNKDVTSLDWN-TNGTLLATGSYDGFARIWTEDGN--LASTLGQHKGPIFALKWNRKGN 291
Query: 189 LLATTCKDKTLRIIDPRKGQVVAERFAAH 217
+ + DKT I D G+ ++F H
Sbjct: 292 YILSAGVDKTTIIWDAHTGE-AKQQFPFH 319
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/167 (26%), Positives = 64/167 (38%), Gaps = 54/167 (32%)
Query: 79 GHTAP----VLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRV 134
GH P V +DW N ++A+ S D +W T N+ TL H +
Sbjct: 231 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIW-----TEDGNLAS---TLGQHKGPI 281
Query: 135 GILSWHPTARNVLLSAGGDNVIIIWNVGTGEV----------LLSLD------------D 172
L W+ N +LSAG D IIW+ TGE L +D D
Sbjct: 282 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 340
Query: 173 M------------------HPDVIHSVCWNSNGSLLATTCKDKTLRI 201
M H + ++++ W+ +G LLA+ D TL+I
Sbjct: 341 MCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKI 387
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 59.3 bits (142), Expect = 7e-09
Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 17/148 (11%)
Query: 71 DKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGH 130
D+ GHT V I W P + ++AS SDD T+ +W + + + L+ H
Sbjct: 351 DRPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHD-------LQAH 402
Query: 131 SKRVGILSWHPTA-------RNVLL-SAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
+K + + W PT N++L SA D+ + +W++ G +L H + ++SV
Sbjct: 403 NKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL-TKHQEPVYSVA 461
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVV 210
++ +G LA+ DK + I + + G +V
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNTQSGNLV 489
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 18/135 (13%)
Query: 80 HTAPVLDIDWCPH-------NDNV-IASASDDTTIMVWQIPDYTPMRNITEPIITLEGHS 131
H + I W P N N+ +ASAS D+T+ +W I +T+ H
Sbjct: 402 HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQ 454
Query: 132 KRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLA 191
+ V +++ P + L S D + IWN +G ++ S I VCWN+ G +
Sbjct: 455 EPVYSVAFSPDGK-YLASGSFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVG 511
Query: 192 TTCKDKTLRIIDPRK 206
+ D ++ ++D RK
Sbjct: 512 ASASDGSVCVLDLRK 526
Score = 42.4 bits (98), Expect = 0.001
Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 14/88 (15%)
Query: 127 LEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNV------GTGEVLLS--LDDMHPDV- 177
L GH V I +W+P + ++L S GD+ IWN+ G+ +++L + + DV
Sbjct: 177 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 235
Query: 178 ----IHSVCWNSNGSLLATTCKDKTLRI 201
+ S+ WN+NG+LLAT D RI
Sbjct: 236 SNKDVTSLDWNTNGTLLATGSYDGFARI 263
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 76 LVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYT---PMRNITEPIITLEGH-- 130
++ GH + V W P +D ++AS S D+T +W + + + + + I GH
Sbjct: 176 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 131 --SKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGS 188
+K V L W+ T +L + D IW L S H I ++ WN G+
Sbjct: 235 PSNKDVTSLDWN-TNGTLLATGSYDGFARIWTEDGN--LASTLGQHKGPIFALKWNRKGN 291
Query: 189 LLATTCKDKTLRIIDPRKGQVVAERFAAH 217
+ + DKT I D G+ ++F H
Sbjct: 292 YILSAGVDKTTIIWDAHTGE-AKQQFPFH 319
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/167 (26%), Positives = 64/167 (38%), Gaps = 54/167 (32%)
Query: 79 GHTAP----VLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRV 134
GH P V +DW N ++A+ S D +W T N+ TL H +
Sbjct: 231 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIW-----TEDGNLAS---TLGQHKGPI 281
Query: 135 GILSWHPTARNVLLSAGGDNVIIIWNVGTGEV----------LLSLD------------D 172
L W+ N +LSAG D IIW+ TGE L +D D
Sbjct: 282 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 340
Query: 173 M------------------HPDVIHSVCWNSNGSLLATTCKDKTLRI 201
M H + ++++ W+ +G LLA+ D TL+I
Sbjct: 341 MCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKI 387
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 59.3 bits (142), Expect = 7e-09
Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 17/148 (11%)
Query: 71 DKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGH 130
D+ GHT V I W P + ++AS SDD T+ +W + + + L+ H
Sbjct: 402 DRPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHD-------LQAH 453
Query: 131 SKRVGILSWHPTA-------RNVLL-SAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
+K + + W PT N++L SA D+ + +W++ G +L H + ++SV
Sbjct: 454 NKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL-TKHQEPVYSVA 512
Query: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVV 210
++ +G LA+ DK + I + + G +V
Sbjct: 513 FSPDGKYLASGSFDKCVHIWNTQSGNLV 540
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 18/135 (13%)
Query: 80 HTAPVLDIDWCPH-------NDNV-IASASDDTTIMVWQIPDYTPMRNITEPIITLEGHS 131
H + I W P N N+ +ASAS D+T+ +W I +T+ H
Sbjct: 453 HNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQ 505
Query: 132 KRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLA 191
+ V +++ P + L S D + IWN +G ++ S I VCWN+ G +
Sbjct: 506 EPVYSVAFSPDGK-YLASGSFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVG 562
Query: 192 TTCKDKTLRIIDPRK 206
+ D ++ ++D RK
Sbjct: 563 ASASDGSVCVLDLRK 577
Score = 42.4 bits (98), Expect = 0.001
Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 14/88 (15%)
Query: 127 LEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNV------GTGEVLLS--LDDMHPDV- 177
L GH V I +W+P + ++L S GD+ IWN+ G+ +++L + + DV
Sbjct: 228 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 286
Query: 178 ----IHSVCWNSNGSLLATTCKDKTLRI 201
+ S+ WN+NG+LLAT D RI
Sbjct: 287 SNKDVTSLDWNTNGTLLATGSYDGFARI 314
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 76 LVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYT---PMRNITEPIITLEGH-- 130
++ GH + V W P +D ++AS S D+T +W + + + + + I GH
Sbjct: 227 VLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 131 --SKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGS 188
+K V L W+ T +L + D IW L S H I ++ WN G+
Sbjct: 286 PSNKDVTSLDWN-TNGTLLATGSYDGFARIWTEDGN--LASTLGQHKGPIFALKWNRKGN 342
Query: 189 LLATTCKDKTLRIIDPRKGQVVAERFAAH 217
+ + DKT I D G+ ++F H
Sbjct: 343 YILSAGVDKTTIIWDAHTGE-AKQQFPFH 370
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/167 (26%), Positives = 64/167 (38%), Gaps = 54/167 (32%)
Query: 79 GHTAP----VLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRV 134
GH P V +DW N ++A+ S D +W T N+ TL H +
Sbjct: 282 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIW-----TEDGNLAS---TLGQHKGPI 332
Query: 135 GILSWHPTARNVLLSAGGDNVIIIWNVGTGEV----------LLSLD------------D 172
L W+ N +LSAG D IIW+ TGE L +D D
Sbjct: 333 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 391
Query: 173 M------------------HPDVIHSVCWNSNGSLLATTCKDKTLRI 201
M H + ++++ W+ +G LLA+ D TL+I
Sbjct: 392 MCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKI 438
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,379,027
Number of Sequences: 37866
Number of extensions: 912052
Number of successful extensions: 3831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 163
Number of HSP's that attempted gapping in prelim test: 2823
Number of HSP's gapped (non-prelim): 763
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.