Search of human proteins with 109255247

Search of human proteins with 109255247

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109255247 jumonji domain containing 2C isoform 1 [Homo
sapiens]
         (1056 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]   2185   0.0  
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]   2072   0.0  
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]   1672   0.0  
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]   1672   0.0  
gi|98986459 jumonji domain containing 2A [Homo sapiens]              1180   0.0  
gi|45504380 jumonji domain containing 2B [Homo sapiens]              1137   0.0  
gi|39653317 jumonji domain containing 2D [Homo sapiens]               520   e-147
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]           510   e-144
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]           510   e-144
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]           510   e-144
gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]           509   e-144
gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]           509   e-144
gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]           509   e-144
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa...   144   4e-34
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa...   144   4e-34
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H...   137   4e-32
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H...   137   4e-32
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H...   135   3e-31
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho...   135   3e-31
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]     133   8e-31
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ...   133   8e-31
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H...   131   3e-30
gi|51173722 bromodomain and PHD finger-containing protein 1 isof...   130   9e-30
gi|51173720 bromodomain and PHD finger-containing protein 1 isof...   130   9e-30
gi|11321642 bromodomain containing protein 1 [Homo sapiens]           114   6e-25
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi...   105   2e-22
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora...   104   4e-22
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca...   104   5e-22
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat...   104   5e-22
gi|117190334 PHD finger protein 16 [Homo sapiens]                     102   2e-21

>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
          Length = 1056

 Score = 2185 bits (5663), Expect = 0.0
 Identities = 1056/1056 (100%), Positives = 1056/1056 (100%)

Query: 1    MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 60
            MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC
Sbjct: 1    MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 60

Query: 61   YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 120
            YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE
Sbjct: 61   YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 120

Query: 121  RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 180
            RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF
Sbjct: 121  RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 180

Query: 181  GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 240
            GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL
Sbjct: 181  GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 240

Query: 241  RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 300
            RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID
Sbjct: 241  RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 300

Query: 301  YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 360
            YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL
Sbjct: 301  YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 360

Query: 361  QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 420
            QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV
Sbjct: 361  QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 420

Query: 421  KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 480
            KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI
Sbjct: 421  KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 480

Query: 481  SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 540
            SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE
Sbjct: 481  SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 540

Query: 541  PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
            PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV
Sbjct: 541  PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600

Query: 601  LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 660
            LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS
Sbjct: 601  LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 660

Query: 661  NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 720
            NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK
Sbjct: 661  NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 720

Query: 721  CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 780
            CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV
Sbjct: 721  CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 780

Query: 781  AVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTC 840
            AVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTC
Sbjct: 781  AVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTC 840

Query: 841  AHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVM 900
            AHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVM
Sbjct: 841  AHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVM 900

Query: 901  AVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGS 960
            AVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGS
Sbjct: 901  AVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGS 960

Query: 961  NIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGER 1020
            NIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGER
Sbjct: 961  NIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGER 1020

Query: 1021 KRQRVLSSRFKNEYVADPVYRTFLKSSFQKKCQKRQ 1056
            KRQRVLSSRFKNEYVADPVYRTFLKSSFQKKCQKRQ
Sbjct: 1021 KRQRVLSSRFKNEYVADPVYRTFLKSSFQKKCQKRQ 1056


>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
          Length = 1047

 Score = 2072 bits (5368), Expect = 0.0
 Identities = 999/1001 (99%), Positives = 1000/1001 (99%)

Query: 1    MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 60
            MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC
Sbjct: 1    MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 60

Query: 61   YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 120
            YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE
Sbjct: 61   YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 120

Query: 121  RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 180
            RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF
Sbjct: 121  RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 180

Query: 181  GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 240
            GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL
Sbjct: 181  GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 240

Query: 241  RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 300
            RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID
Sbjct: 241  RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 300

Query: 301  YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 360
            YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL
Sbjct: 301  YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 360

Query: 361  QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 420
            QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV
Sbjct: 361  QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 420

Query: 421  KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 480
            KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI
Sbjct: 421  KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 480

Query: 481  SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 540
            SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE
Sbjct: 481  SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 540

Query: 541  PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
            PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV
Sbjct: 541  PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600

Query: 601  LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 660
            LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS
Sbjct: 601  LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 660

Query: 661  NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 720
            NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK
Sbjct: 661  NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 720

Query: 721  CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 780
            CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV
Sbjct: 721  CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 780

Query: 781  AVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTC 840
            AVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTC
Sbjct: 781  AVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTC 840

Query: 841  AHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVM 900
            AHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVM
Sbjct: 841  AHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVM 900

Query: 901  AVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGS 960
            AVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGS
Sbjct: 901  AVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGS 960

Query: 961  NIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTA 1001
            NIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARF +A
Sbjct: 961  NIAHMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFVSA 1001


>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
          Length = 813

 Score = 1672 bits (4331), Expect = 0.0
 Identities = 808/808 (100%), Positives = 808/808 (100%)

Query: 1   MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 60
           MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC
Sbjct: 1   MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 60

Query: 61  YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 120
           YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE
Sbjct: 61  YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 120

Query: 121 RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 180
           RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF
Sbjct: 121 RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 180

Query: 181 GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 240
           GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL
Sbjct: 181 GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 240

Query: 241 RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 300
           RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID
Sbjct: 241 RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 300

Query: 301 YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 360
           YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL
Sbjct: 301 YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 360

Query: 361 QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 420
           QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV
Sbjct: 361 QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 420

Query: 421 KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 480
           KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI
Sbjct: 421 KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 480

Query: 481 SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 540
           SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE
Sbjct: 481 SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 540

Query: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
           PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV
Sbjct: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600

Query: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 660
           LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS
Sbjct: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 660

Query: 661 NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 720
           NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK
Sbjct: 661 NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 720

Query: 721 CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 780
           CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV
Sbjct: 721 CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 780

Query: 781 AVPEVRFTNVPERTQIDVGRIPLQRLKL 808
           AVPEVRFTNVPERTQIDVGRIPLQRLKL
Sbjct: 781 AVPEVRFTNVPERTQIDVGRIPLQRLKL 808


>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
          Length = 835

 Score = 1672 bits (4331), Expect = 0.0
 Identities = 808/808 (100%), Positives = 808/808 (100%)

Query: 1   MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 60
           MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC
Sbjct: 23  MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQC 82

Query: 61  YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 120
           YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE
Sbjct: 83  YDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLE 142

Query: 121 RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 180
           RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF
Sbjct: 143 RKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYF 202

Query: 181 GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 240
           GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL
Sbjct: 203 GMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFL 262

Query: 241 RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 300
           RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID
Sbjct: 263 RHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWID 322

Query: 301 YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 360
           YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL
Sbjct: 323 YGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWL 382

Query: 361 QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 420
           QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV
Sbjct: 383 QRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV 442

Query: 421 KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 480
           KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI
Sbjct: 443 KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSI 502

Query: 481 SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 540
           SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE
Sbjct: 503 SSEADDSIPLSSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLE 562

Query: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
           PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV
Sbjct: 563 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 622

Query: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 660
           LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS
Sbjct: 623 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSS 682

Query: 661 NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 720
           NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK
Sbjct: 683 NEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAK 742

Query: 721 CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 780
           CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV
Sbjct: 743 CCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAV 802

Query: 781 AVPEVRFTNVPERTQIDVGRIPLQRLKL 808
           AVPEVRFTNVPERTQIDVGRIPLQRLKL
Sbjct: 803 AVPEVRFTNVPERTQIDVGRIPLQRLKL 830


>gi|98986459 jumonji domain containing 2A [Homo sapiens]
          Length = 1064

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 596/1092 (54%), Positives = 758/1092 (69%), Gaps = 77/1092 (7%)

Query: 3    VAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYD 62
            +A     LNPS +IMTF P+MEEFR F++Y+AY+ES+GAHRAGLAKV+PPKEWKPR  YD
Sbjct: 1    MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60

Query: 63   DIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERK 122
            DID+L+IPAPIQQ+VTGQSGLFTQYNIQKKAMTV+EFR++ANS KYCTPRY ++E+LERK
Sbjct: 61   DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK 120

Query: 123  YWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGM 182
            YWKNLTF  PIYGAD+NG++Y++ VDEWNI RL T+LD+VE+E GI+IEGVNTPYLYFGM
Sbjct: 121  YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM 180

Query: 183  WKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRH 242
            WKT+FAWHTEDMDLYSINYLHFGEPKSWY++PPEHGKRLERLA+GFFP S+Q C+AFLRH
Sbjct: 181  WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH 240

Query: 243  KMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYG 302
            KMTLISP +LKKYGIPFDK+TQEAGEFMITFPYGYHAGFNHGFNCAESTNFAT RWI+YG
Sbjct: 241  KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG 300

Query: 303  KVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQR 362
            K A LC+CRKDMVKISMD+FVRKFQP+RY+LWK GKD   IDHT P    TPE   +L+ 
Sbjct: 301  KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP----TPEAAEFLKE 356

Query: 363  RRKVRKASRSFQCARSTSKRPKADEEE--------------------EVSDEVDGAEV-P 401
                 +A    +C     +  +  EE                     E+  EV  +E+ P
Sbjct: 357  SELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFP 416

Query: 402  NPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNL-----SDHIKLSGNSCL 456
              D  ++  +++E   A   +R T +S          QVE  L     SD  ++      
Sbjct: 417  KEDLSSEQYEMTECPAALAPVRPTHSSVR--------QVEDGLTFPDYSDSTEVKFEELK 468

Query: 457  STSVTEDIKTEDDKAYAY-RSVPSIS---------SEADDSIPLSSGYEKPEKSDPSELS 506
            +  + E+ + E+  A A   SV   S         S+   S  L SG  +   S  SE S
Sbjct: 469  NVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETS 528

Query: 507  WPKSPESCSSVAESNGVLTEGEESDVESHGNG---LEPGEIPAVPSGE-RNSFKVPSIAE 562
                P SC +  ++ GVLT      V S+  G   +  GE      G    SF    +AE
Sbjct: 529  ---EPLSCRAQGQT-GVLT------VHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAE 578

Query: 563  ---------GENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESW 613
                      ENK SK  R PLS+ P   P  LV Q+  SD+E  E L+ EEE EETE+W
Sbjct: 579  VADEYMFSLEENKKSKGRRQPLSKLPRHHP--LVLQECVSDDETSEQLTPEEEAEETEAW 636

Query: 614  AKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLD 673
            AKPL  LWQ + PNF AE+E+N T+A+  PHCA+C +   YH+ +      +        
Sbjct: 637  AKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNC---GNAS 693

Query: 674  EVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIP 733
            ++   + +TKPLIPEMCF  +  + + +    +LEEDGTS+L+SC KC VRVHASCYG+P
Sbjct: 694  DLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVP 753

Query: 734  SHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPER 793
              +  + W+C+RC  NA   +CCLC+LRGGAL++  +++W HV CAVA+ E RF N+ ER
Sbjct: 754  PAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAER 813

Query: 794  TQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDW 853
            + +DV +IPL R KLKCIFC+ R KR +G C+QCS+GRCP +FHV+CA AAGV+M+PDDW
Sbjct: 814  SPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDW 873

Query: 854  PYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEVMFD 913
            P+VV ITCFRHK+    ++K   + I+ GQ VI+KH+N R+Y C V+ +T++TFYEV FD
Sbjct: 874  PFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFD 933

Query: 914  DGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDG 973
            DGSFS + +PEDIVS+DCL+ GPPAEGEVVQV+W DG++YGAK+  S+   MYQVEFEDG
Sbjct: 934  DGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDG 993

Query: 974  SQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKRQRVLSSRFKNE 1033
            SQ+ +KR+D+YTLDEELPKRVK+R S ASDMRF + F   ++ Q E+KRQRV++SR++ +
Sbjct: 994  SQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYRED 1052

Query: 1034 YVADPVYRTFLK 1045
            Y+   +YR  ++
Sbjct: 1053 YIEPALYRAIME 1064


>gi|45504380 jumonji domain containing 2B [Homo sapiens]
          Length = 1096

 Score = 1137 bits (2942), Expect = 0.0
 Identities = 583/1065 (54%), Positives = 724/1065 (67%), Gaps = 65/1065 (6%)

Query: 11   NPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIP 70
            NPSCKIMTFRP+MEEF++FNKY+AY+ES+GAHRAGLAK+IPPKEWKPRQ YDDID+++IP
Sbjct: 10   NPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIP 69

Query: 71   APIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFV 130
            APIQQ+VTGQSGLFTQYNIQKKAMTV E+R+LANS KYCTPR+ D++DLERKYWKNLTFV
Sbjct: 70   APIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFV 129

Query: 131  APIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWH 190
            +PIYGADI+GS+YD+ V +WNI  L T+LD+VE ECG  IEGVNTPYLYFGMWKTTFAWH
Sbjct: 130  SPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWH 189

Query: 191  TEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPS 250
            TEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLA GFFP SSQGCDAFLRHKMTLISP 
Sbjct: 190  TEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPI 249

Query: 251  VLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTC 310
            +LKKYGIPF +ITQEAGEFMITFPYGYHAGFNHGFNCAESTNFAT+RWIDYGKVA  CTC
Sbjct: 250  ILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTC 309

Query: 311  RKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQRRRKVR-KA 369
            RKDMVKISMD+FVR  QP+RY+LWKQGKD+  +DHT+PT  ++PE+ +W   R  ++ K 
Sbjct: 310  RKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKL 369

Query: 370  SRSFQCARSTSKRPKADE---------------------EEEVSDEVDGAEVPNPDSVTD 408
             R     RS  K+PK ++                     +EE   EVD  E         
Sbjct: 370  LRRSHRKRSQPKKPKPEDPKFPGEGTAGAALLEEAGGSVKEEAGPEVDPEEEEEEPQPLP 429

Query: 409  DLKVSEKSE--AAVKLRNTEASSEEESSASRMQVEQ--NLSDHIKLSGNSCLSTSVTEDI 464
              + +E +E     KLR T+A SE +  +  +   Q      H        L + +   +
Sbjct: 430  HGREAEGAEEDGRGKLRPTKAKSERKKKSFGLLPPQLPPPPAHFPSEEALWLPSPLEPPV 489

Query: 465  KTEDDKAYAYRSVPSISSEADDSIPLSSGYEKPEK--------SDPSELSWPKSPESCSS 516
                  A     +P+  +     +P      KP            P + ++ +   SC  
Sbjct: 490  LGPGPAAMEESPLPAPLNVVPPEVPSEELEAKPRPIIPMLYVVPRPGKAAFNQEHVSCQQ 549

Query: 517  VAE---SNGVLTEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSIAEGENKTS----- 568
              E     G   +   S +E  G      E  A  SG           EG+  ++     
Sbjct: 550  AFEHFAQKGPTWKEPVSPMELTG-----PEDGAASSGAGRMETKARAGEGQAPSTFSKLK 604

Query: 569  ----KSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESWAKPLIHL-WQT 623
                KS RHPL RPP RSP+++VKQ+A SDEE     S EE+V + ++  +PL+ L W+ 
Sbjct: 605  MEIKKSRRHPLGRPPTRSPLSVVKQEASSDEE-ASPFSGEEDVSDPDA-LRPLLSLQWKN 662

Query: 624  KSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLDE------VVT 677
            ++ +F AE+++NA  AR +P+CAICTL  PY +   + +E        L E         
Sbjct: 663  RAASFQAERKFNAAAARTEPYCAICTLFYPYCQALQTEKEAPI---ASLGEGCPATLPSK 719

Query: 678  SEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIPSHEI 737
            S  KT+PLIPEMCF    EN E  P N+++ +DGTS LI+C KCC++VHASCYGI    +
Sbjct: 720  SRQKTRPLIPEMCFTSGGENTEPLPANSYIGDDGTSPLIACGKCCLQVHASCYGIRPELV 779

Query: 738  CDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQID 797
             +GW C+RC  +AWTAECCLCNLRGGAL+ T + +W HV+CA+AVPE RF NV ER  +D
Sbjct: 780  NEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEARFLNVIERHPVD 839

Query: 798  VGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVV 857
            +  IP QR KLKC++CR R+K+VSGACIQCSY  C  SFHVTCAHAAGVLMEPDDWPYVV
Sbjct: 840  ISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVV 899

Query: 858  NITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEVMFDDGSF 917
            +ITC +HK   +       + +S+GQ VITK+RN  YY CRV+   SQT YEV FDDGS+
Sbjct: 900  SITCLKHKSGGHAVQLL--RAVSLGQVVITKNRNGLYYRCRVIGAASQTCYEVNFDDGSY 957

Query: 918  SRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDGSQIA 977
            S + +PE I SRDC++LGPP+EGE+V+++W DG LY AK+  S  +H+YQVEFEDGSQ+ 
Sbjct: 958  SDNLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLT 1017

Query: 978  MKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKR 1022
            +KR DI+TL+EELPKRV++R S ++    E  F G +    +R R
Sbjct: 1018 VKRGDIFTLEEELPKRVRSRLSLSTGAPQEPAFSGEEAKAAKRPR 1062


>gi|39653317 jumonji domain containing 2D [Homo sapiens]
          Length = 523

 Score =  520 bits (1339), Expect = e-147
 Identities = 232/343 (67%), Positives = 286/343 (83%), Gaps = 1/343 (0%)

Query: 11  NPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIP 70
           NP+C IM F P+ EEF +F+KY+AYMES+GAHRAGLAK+IPPKEWK R+ YD+I  +LI 
Sbjct: 13  NPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIA 72

Query: 71  APIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFV 130
            P+QQ+ +G++G+FTQY+ +KKAMTV E+R LANS KY TP + ++EDLERKYWKN  + 
Sbjct: 73  TPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYN 132

Query: 131 APIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWH 190
           +PIYGADI+GS++DE   +WN+  L T+ D++E+ECG+ IEGVNTPYLYFGMWKTTFAWH
Sbjct: 133 SPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWH 192

Query: 191 TEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPS 250
           TEDMDLYSINYLH GEPK+WY +PPEHG+RLERLA+  FP SS+GC AFLRHK+ LISP+
Sbjct: 193 TEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPT 252

Query: 251 VLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTC 310
           VLK+ GIPF++ITQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWIDYGK+A  C+C
Sbjct: 253 VLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSC 312

Query: 311 RKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKP-TPAS 352
            +  V  SMD FVR  QP+RY LWK+G+D   +DH +P  PAS
Sbjct: 313 GEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPAS 355


>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score =  510 bits (1313), Expect = e-144
 Identities = 229/352 (65%), Positives = 285/352 (80%)

Query: 8   SPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNL 67
           SP N S  IMTF P+MEEF +FN Y+AYMES+GAHRAGLAKVIPPKEWK RQ YDDI+++
Sbjct: 7   SPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKARQMYDDIEDI 66

Query: 68  LIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNL 127
           LI  P+QQ+ +GQ G+FTQY+ +KKAM V ++R LANS KY TP + ++ DLE++YWK+ 
Sbjct: 67  LIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQNFADLEQRYWKSH 126

Query: 128 TFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTF 187
               PIYGADI+GS+++E   +WN+  L T+LD++E+ECG+ IEGVNTPYLYFGMWKTTF
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 188 AWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLI 247
           AWHTEDMDLYSINYLHFGEPK+WY +PPEHG+RLE LA+  FP +S+GC+ FLRHK+ LI
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALI 246

Query: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKL 307
           SP+VLKK GIPF+++TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWIDYGKVA  
Sbjct: 247 SPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQ 306

Query: 308 CTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAW 359
           C+C +  V  SMD FVR  QP+ Y+LWK  +D+  +D+ +P  A + E   W
Sbjct: 307 CSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNW 358


>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score =  510 bits (1313), Expect = e-144
 Identities = 229/352 (65%), Positives = 285/352 (80%)

Query: 8   SPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNL 67
           SP N S  IMTF P+MEEF +FN Y+AYMES+GAHRAGLAKVIPPKEWK RQ YDDI+++
Sbjct: 7   SPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKARQMYDDIEDI 66

Query: 68  LIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNL 127
           LI  P+QQ+ +GQ G+FTQY+ +KKAM V ++R LANS KY TP + ++ DLE++YWK+ 
Sbjct: 67  LIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQNFADLEQRYWKSH 126

Query: 128 TFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTF 187
               PIYGADI+GS+++E   +WN+  L T+LD++E+ECG+ IEGVNTPYLYFGMWKTTF
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 188 AWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLI 247
           AWHTEDMDLYSINYLHFGEPK+WY +PPEHG+RLE LA+  FP +S+GC+ FLRHK+ LI
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALI 246

Query: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKL 307
           SP+VLKK GIPF+++TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWIDYGKVA  
Sbjct: 247 SPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQ 306

Query: 308 CTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAW 359
           C+C +  V  SMD FVR  QP+ Y+LWK  +D+  +D+ +P  A + E   W
Sbjct: 307 CSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNW 358


>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score =  510 bits (1313), Expect = e-144
 Identities = 229/352 (65%), Positives = 285/352 (80%)

Query: 8   SPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNL 67
           SP N S  IMTF P+MEEF +FN Y+AYMES+GAHRAGLAKVIPPKEWK RQ YDDI+++
Sbjct: 7   SPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKARQMYDDIEDI 66

Query: 68  LIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNL 127
           LI  P+QQ+ +GQ G+FTQY+ +KKAM V ++R LANS KY TP + ++ DLE++YWK+ 
Sbjct: 67  LIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQNFADLEQRYWKSH 126

Query: 128 TFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTF 187
               PIYGADI+GS+++E   +WN+  L T+LD++E+ECG+ IEGVNTPYLYFGMWKTTF
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 188 AWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLI 247
           AWHTEDMDLYSINYLHFGEPK+WY +PPEHG+RLE LA+  FP +S+GC+ FLRHK+ LI
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALI 246

Query: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKL 307
           SP+VLKK GIPF+++TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWIDYGKVA  
Sbjct: 247 SPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQ 306

Query: 308 CTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAW 359
           C+C +  V  SMD FVR  QP+ Y+LWK  +D+  +D+ +P  A + E   W
Sbjct: 307 CSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNW 358


>gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 506

 Score =  509 bits (1311), Expect = e-144
 Identities = 228/352 (64%), Positives = 287/352 (81%)

Query: 8   SPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNL 67
           SP N S  IMTF P+MEEF +FN Y+AYMES+GAH+AGLAKVIPPKEWK RQ YDDI+++
Sbjct: 7   SPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMYDDIEDI 66

Query: 68  LIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNL 127
           LI  P+QQ+ +GQ G+FTQY+ +KKAM V ++R+LANS KY TP + ++ DLE++YWK+ 
Sbjct: 67  LIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHRNFADLEQRYWKSH 126

Query: 128 TFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTF 187
               PIYGADI+GS+++E   +WN+  L T+LD++E+ECG+ IEGVNTPYLYFGMWKTTF
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 188 AWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLI 247
           AWHTEDMDLYSINYLHFGEPK+WY +PPEHG+ LERLA+  FP  S+GC+AFLRHK+ LI
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALI 246

Query: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKL 307
           SP+VLK+ GIPF+ +TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWIDYGK+A  
Sbjct: 247 SPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQ 306

Query: 308 CTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAW 359
           C+C +  V  SMD FVR  QP+ Y+LWK  +D+  ++HT+P  A + E+  W
Sbjct: 307 CSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQELSNW 358


>gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 506

 Score =  509 bits (1311), Expect = e-144
 Identities = 228/352 (64%), Positives = 287/352 (81%)

Query: 8   SPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNL 67
           SP N S  IMTF P+MEEF +FN Y+AYMES+GAH+AGLAKVIPPKEWK RQ YDDI+++
Sbjct: 7   SPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMYDDIEDI 66

Query: 68  LIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNL 127
           LI  P+QQ+ +GQ G+FTQY+ +KKAM V ++R+LANS KY TP + ++ DLE++YWK+ 
Sbjct: 67  LIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHRNFADLEQRYWKSH 126

Query: 128 TFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTF 187
               PIYGADI+GS+++E   +WN+  L T+LD++E+ECG+ IEGVNTPYLYFGMWKTTF
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 188 AWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLI 247
           AWHTEDMDLYSINYLHFGEPK+WY +PPEHG+ LERLA+  FP  S+GC+AFLRHK+ LI
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALI 246

Query: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKL 307
           SP+VLK+ GIPF+ +TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWIDYGK+A  
Sbjct: 247 SPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQ 306

Query: 308 CTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAW 359
           C+C +  V  SMD FVR  QP+ Y+LWK  +D+  ++HT+P  A + E+  W
Sbjct: 307 CSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQELSNW 358


>gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 506

 Score =  509 bits (1311), Expect = e-144
 Identities = 228/352 (64%), Positives = 287/352 (81%)

Query: 8   SPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNL 67
           SP N S  IMTF P+MEEF +FN Y+AYMES+GAH+AGLAKVIPPKEWK RQ YDDI+++
Sbjct: 7   SPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMYDDIEDI 66

Query: 68  LIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNL 127
           LI  P+QQ+ +GQ G+FTQY+ +KKAM V ++R+LANS KY TP + ++ DLE++YWK+ 
Sbjct: 67  LIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHQNFADLEQRYWKSH 126

Query: 128 TFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTF 187
               PIYGADI+GS+++E   +WN+  L T+LD++E+ECG+ IEGVNTPYLYFGMWKTTF
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 188 AWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLI 247
           AWHTEDMDLYSINYLHFGEPK+WY +PPEHG+ LERLA+  FP  S+GC+AFLRHK+ LI
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALI 246

Query: 248 SPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKL 307
           SP+VLK+ GIPF+ +TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWIDYGK+A  
Sbjct: 247 SPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQ 306

Query: 308 CTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAW 359
           C+C +  V  SMD FVR  QP+ Y+LWK  +D+  ++HT+P  A + E+  W
Sbjct: 307 CSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQELSNW 358


>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
           sapiens]
          Length = 1690

 Score =  144 bits (363), Expect = 4e-34
 Identities = 75/235 (31%), Positives = 127/235 (54%), Gaps = 26/235 (11%)

Query: 95  TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTFVAPI----YGADINGSIYDEG 146
           T++ F ++A++ K   +  P ++   +L E+++W+ ++ +       YGADI+   +  G
Sbjct: 362 TLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSG 421

Query: 147 ------------------VDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
                             +  WN+  +  +   V     + I G+  P+LY GM  ++F 
Sbjct: 422 FPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFC 481

Query: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
           WH ED   YSINYLH+GEPK+WY +P    ++LE + +   P   +     L   +T+++
Sbjct: 482 WHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMN 541

Query: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
           P+VL ++G+P  +  Q AGEF++TFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 542 PNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGR 596



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKP 57
          P C +  F PS EEF +   ++  +    A + G+ K+ PPK+W+P
Sbjct: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59


>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
           sapiens]
          Length = 1641

 Score =  144 bits (363), Expect = 4e-34
 Identities = 75/235 (31%), Positives = 127/235 (54%), Gaps = 26/235 (11%)

Query: 95  TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTFVAPI----YGADINGSIYDEG 146
           T++ F ++A++ K   +  P ++   +L E+++W+ ++ +       YGADI+   +  G
Sbjct: 362 TLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSG 421

Query: 147 ------------------VDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
                             +  WN+  +  +   V     + I G+  P+LY GM  ++F 
Sbjct: 422 FPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFC 481

Query: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
           WH ED   YSINYLH+GEPK+WY +P    ++LE + +   P   +     L   +T+++
Sbjct: 482 WHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMN 541

Query: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
           P+VL ++G+P  +  Q AGEF++TFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 542 PNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGR 596



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKP 57
          P C +  F PS EEF +   ++  +    A + G+ K+ PPK+W+P
Sbjct: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59


>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
           sapiens]
          Length = 1379

 Score =  137 bits (346), Expect = 4e-32
 Identities = 82/239 (34%), Positives = 125/239 (52%), Gaps = 34/239 (14%)

Query: 95  TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
           T++ F ++A+S K   +  P ++   +L E+++W+ +      V   YGADI+   +  G
Sbjct: 326 TLQSFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSG 385

Query: 147 ------------------VDEWNIARLNTVLDVVEEE--CGIS--IEGVNTPYLYFGMWK 184
                                WN+     V+ V+E+   C I+  I G+  P+LY GM  
Sbjct: 386 FPVSDSKRHLTPEEEEYATSGWNL----NVMPVLEQSVLCHINADISGMKVPWLYVGMVF 441

Query: 185 TTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKM 244
           + F WH ED   YSINYLH+GEPK+WY +P    + LE + +   P         L   +
Sbjct: 442 SAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLV 501

Query: 245 TLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
           TL++P+ L  +G+P  +  Q AGEF+ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 502 TLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 560


>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
           sapiens]
          Length = 1560

 Score =  137 bits (346), Expect = 4e-32
 Identities = 82/239 (34%), Positives = 125/239 (52%), Gaps = 34/239 (14%)

Query: 95  TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
           T++ F ++A+S K   +  P ++   +L E+++W+ +      V   YGADI+   +  G
Sbjct: 393 TLQSFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSG 452

Query: 147 ------------------VDEWNIARLNTVLDVVEEE--CGIS--IEGVNTPYLYFGMWK 184
                                WN+     V+ V+E+   C I+  I G+  P+LY GM  
Sbjct: 453 FPVSDSKRHLTPEEEEYATSGWNL----NVMPVLEQSVLCHINADISGMKVPWLYVGMVF 508

Query: 185 TTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKM 244
           + F WH ED   YSINYLH+GEPK+WY +P    + LE + +   P         L   +
Sbjct: 509 SAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLV 568

Query: 245 TLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
           TL++P+ L  +G+P  +  Q AGEF+ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 569 TLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 627



 Score = 37.0 bits (84), Expect = 0.098
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 71
          P C +  F PS  EFR+   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 12 PECPV--FEPSWAEFRDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67

Query: 72 PIQQM 76
           IQ++
Sbjct: 68 RIQRL 72


>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
           sapiens]
          Length = 1482

 Score =  135 bits (339), Expect = 3e-31
 Identities = 72/209 (34%), Positives = 106/209 (50%), Gaps = 22/209 (10%)

Query: 117 EDLERKYWKNLTF----VAPIYGADINGSIYDEG------------------VDEWNIAR 154
           E +E+++W+ ++     V   YGADI+   +  G                     WN+  
Sbjct: 352 ELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNV 411

Query: 155 LNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIP 214
           +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+WY +P
Sbjct: 412 MPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVP 471

Query: 215 PEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFP 274
               + LE + +   P         L   +TL++P+ L  +G+P  +  Q AGEF+ITFP
Sbjct: 472 SLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFP 531

Query: 275 YGYHAGFNHGFNCAESTNFATVRWIDYGK 303
             YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 532 RAYHSGFNQGYNFAEAVNFCTADWLPAGR 560



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 71
          P C +  F PS  EF++   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67

Query: 72 PIQQM 76
           +Q++
Sbjct: 68 RVQRL 72


>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
           sapiens]
          Length = 1539

 Score =  135 bits (339), Expect = 3e-31
 Identities = 72/209 (34%), Positives = 106/209 (50%), Gaps = 22/209 (10%)

Query: 117 EDLERKYWKNLTF----VAPIYGADINGSIYDEG------------------VDEWNIAR 154
           E +E+++W+ ++     V   YGADI+   +  G                     WN+  
Sbjct: 409 ELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNV 468

Query: 155 LNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIP 214
           +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+WY +P
Sbjct: 469 MPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVP 528

Query: 215 PEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFP 274
               + LE + +   P         L   +TL++P+ L  +G+P  +  Q AGEF+ITFP
Sbjct: 529 SLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFP 588

Query: 275 YGYHAGFNHGFNCAESTNFATVRWIDYGK 303
             YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 589 RAYHSGFNQGYNFAEAVNFCTADWLPAGR 617



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 71
          P C +  F PS  EF++   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67

Query: 72 PIQQM 76
           +Q++
Sbjct: 68 RVQRL 72


>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
          Length = 1544

 Score =  133 bits (335), Expect = 8e-31
 Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)

Query: 95  TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
           T++ F ++A++ K   +  P ++   +L E+++W+ ++     V   YGADI    +  G
Sbjct: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437

Query: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
                                WN+  +  +   V       I G+  P+LY GM  ++F 
Sbjct: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497

Query: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
           WH ED   YSINYLH+GEPK+WY +P    ++LE + +   P         L   +T+++
Sbjct: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557

Query: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
           P+ L  + +P  +  Q AGEF+ITFP  YH+GFN GFN AE+ NF TV W+  G+
Sbjct: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
          P C +  F PS EEF +   ++  +    A + G+ KV PP +W+P   C  D+D L   
Sbjct: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84

Query: 71 APIQQM 76
            IQ++
Sbjct: 85 PRIQRL 90



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 5/38 (13%)

Query: 715  LISCAKCCVRVHASCYGIPSHEICDG---WLCARCKRN 749
            +I C  C    H SC  +PS  I  G   WLC  C+R+
Sbjct: 1189 MIQCELCRDAFHTSCVAVPS--ISQGLRIWLCPHCRRS 1224


>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
           domain 1B (RBP2-like), partial [Homo sapiens]
          Length = 977

 Score =  133 bits (335), Expect = 8e-31
 Identities = 77/235 (32%), Positives = 121/235 (51%), Gaps = 26/235 (11%)

Query: 95  TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTF----VAPIYGADINGSIYDEG 146
           T++ F ++A++ K   +  P ++   +L E+++W+ ++     V   YGADI    +  G
Sbjct: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437

Query: 147 V------------------DEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
                                WN+  +  +   V       I G+  P+LY GM  ++F 
Sbjct: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497

Query: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
           WH ED   YSINYLH+GEPK+WY +P    ++LE + +   P         L   +T+++
Sbjct: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557

Query: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
           P+ L  + +P  +  Q AGEF+ITFP  YH+GFN GFN AE+ NF TV W+  G+
Sbjct: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGR 612



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPR-QCYDDIDNLLIP 70
          P C +  F PS EEF +   ++  +    A + G+ KV PP +W+P   C  D+D L   
Sbjct: 30 PECPV--FEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC--DVDKLHFT 84

Query: 71 APIQQM 76
            IQ++
Sbjct: 85 PRIQRL 90


>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
           sapiens]
          Length = 1570

 Score =  131 bits (330), Expect = 3e-30
 Identities = 62/154 (40%), Positives = 87/154 (56%)

Query: 150 WNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKS 209
           WN+  +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+
Sbjct: 495 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 554

Query: 210 WYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEF 269
           WY +P    + LE + +   P         L   +TL++P+ L  +G+P  +  Q AGEF
Sbjct: 555 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 614

Query: 270 MITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
           +ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 615 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 71
          P C +  F PS  EF++   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67

Query: 72 PIQQM 76
           +Q++
Sbjct: 68 RVQRL 72


>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
           2 [Homo sapiens]
          Length = 1214

 Score =  130 bits (326), Expect = 9e-30
 Identities = 104/355 (29%), Positives = 155/355 (43%), Gaps = 56/355 (15%)

Query: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
           P E+   P  E     V S A+ +          + R      + +V +   + EE PE 
Sbjct: 78  PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132

Query: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
            S +E  E   +  K   H  + K  +      +N + +       +    +    PD+ 
Sbjct: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192

Query: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
                       S EE D   E  +DE       ++    KT+ +  IP+  F Y  + +
Sbjct: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252

Query: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
           E            PNA ++ED             +++++ C  C + VH  CYG+P   I
Sbjct: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310

Query: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
            +G WLC RC ++   A +C LC  +GGA KQT + +WAHV+CA+ +PEV F N      
Sbjct: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370

Query: 796 ID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLME 849
           ID +  IP  R KL C  C+   +R SGACIQC    C  +FHVTCA  AG+ M+
Sbjct: 371 IDSIEHIPPARWKLTCYICK---QRGSGACIQCHKANCYTAFHVTCAQQAGLYMK 422


>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform
           1 [Homo sapiens]
          Length = 1220

 Score =  130 bits (326), Expect = 9e-30
 Identities = 104/355 (29%), Positives = 155/355 (43%), Gaps = 56/355 (15%)

Query: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
           P E+   P  E     V S A+ +          + R      + +V +   + EE PE 
Sbjct: 78  PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132

Query: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
            S +E  E   +  K   H  + K  +      +N + +       +    +    PD+ 
Sbjct: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192

Query: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
                       S EE D   E  +DE       ++    KT+ +  IP+  F Y  + +
Sbjct: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252

Query: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
           E            PNA ++ED             +++++ C  C + VH  CYG+P   I
Sbjct: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310

Query: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
            +G WLC RC ++   A +C LC  +GGA KQT + +WAHV+CA+ +PEV F N      
Sbjct: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370

Query: 796 ID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLME 849
           ID +  IP  R KL C  C+   +R SGACIQC    C  +FHVTCA  AG+ M+
Sbjct: 371 IDSIEHIPPARWKLTCYICK---QRGSGACIQCHKANCYTAFHVTCAQQAGLYMK 422


>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
          Length = 1058

 Score =  114 bits (284), Expect = 6e-25
 Identities = 61/145 (42%), Positives = 86/145 (59%), Gaps = 8/145 (5%)

Query: 708 EEDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRN-AWTAECCLCNLRGGAL 765
           E   +++++ C  C + VH  CYG+P   I +G WLC  C ++ A  A+C LC  +GGA 
Sbjct: 224 ECQNSNVILFCDMCNLAVHQECYGVPY--IPEGQWLCRHCLQSRARPADCVLCPNKGGAF 281

Query: 766 KQTKNNKWAHVMCAVAVPEVRFTNVPERTQID-VGRIPLQRLKLKCIFCRHRVKRVSGAC 824
           K+T +++W HV+CA+ +PEV F N      ID V  IP  R KL C  C+   ++  GAC
Sbjct: 282 KKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCK---QKGVGAC 338

Query: 825 IQCSYGRCPASFHVTCAHAAGVLME 849
           IQC    C  +FHVTCA  AG+ M+
Sbjct: 339 IQCHKANCYTAFHVTCAQKAGLYMK 363


>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
           sapiens]
          Length = 1205

 Score =  105 bits (263), Expect = 2e-22
 Identities = 57/141 (40%), Positives = 82/141 (58%), Gaps = 8/141 (5%)

Query: 712 TSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRN-AWTAECCLCNLRGGALKQTK 769
           +++++ C  C + VH  CYG+P   I +G WLC  C ++ +   +C LC  +GGA KQT 
Sbjct: 226 SNVILFCDICNLAVHQECYGVPY--IPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTS 283

Query: 770 NNKWAHVMCAVAVPEVRFTNVPERTQID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCS 828
           +  WAHV+CA+ +PEV F N      I+ +  IP  R KL C  C+   ++  GA IQC 
Sbjct: 284 DGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICK---QKGLGAAIQCH 340

Query: 829 YGRCPASFHVTCAHAAGVLME 849
              C  +FHVTCA  AG+ M+
Sbjct: 341 KVNCYTAFHVTCAQRAGLFMK 361


>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 6 [Homo sapiens]
          Length = 1093

 Score =  104 bits (260), Expect = 4e-22
 Identities = 56/137 (40%), Positives = 75/137 (54%), Gaps = 8/137 (5%)

Query: 721 CCVRVHASCYGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVM 777
           C V VH +CYGI   ++  G W C +C+    A    C LC  + GALK+T N  WAHV+
Sbjct: 30  CSVAVHQACYGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVV 87

Query: 778 CAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHR---VKRVSGACIQCSYGRCPA 834
           CA+ +PEV+F NV     I +  +P  R    C  C  +    K  SGAC+ C+   C  
Sbjct: 88  CALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQ 147

Query: 835 SFHVTCAHAAGVLMEPD 851
           +FHVTCA  AG+L E +
Sbjct: 148 AFHVTCAQMAGLLCEEE 164



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 62/266 (23%), Positives = 95/266 (35%), Gaps = 51/266 (19%)

Query: 364 RKVRKASRSFQCARSTS------KRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEK-S 416
           R+ R AS S Q  +  +      K+ + D+E          E P        +  ++K S
Sbjct: 216 RRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVS 275

Query: 417 EAAVKLRNTEASSEEESSASRMQVEQNLSDHI------KLSG----NSCLSTSVTEDIKT 466
            +A    + EAS++E S +SR    +  S H       KLS     +S  S S +    +
Sbjct: 276 SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSS 335

Query: 467 EDDKAYAYRSVPSISSEADDSI------PLSSGYEKPEKSDPSELSWPKSPE-------- 512
                    +V S+ S  D S       P    Y KP    PS    P +PE        
Sbjct: 336 SSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFE 395

Query: 513 ------------SCSSVAESNGVLTEGEESDVES---HGNGLEPG---EIPAVPSGERNS 554
                         S+   S+G        D +S    G+G   G    +PA+ +    +
Sbjct: 396 QKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPA 455

Query: 555 FKVP--SIAEGENKTSKSWRHPLSRP 578
            + P   + E ++K SK  RH   RP
Sbjct: 456 DETPETGLKEKKHKASKRSRHGPGRP 481


>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform b [Homo sapiens]
          Length = 1011

 Score =  104 bits (259), Expect = 5e-22
 Identities = 65/188 (34%), Positives = 92/188 (48%), Gaps = 20/188 (10%)

Query: 673 DEVVTSEGKTKPLIPEM---CFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASC 729
           D  V+ E +    + EM   C + S+E      P  + +  G         C V VH +C
Sbjct: 5   DRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHG---------CSVAVHQAC 55

Query: 730 YGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVR 786
           YGI   ++  G W C +C+    A    C LC  + GALK+T N  WAHV+CA+ +PEV+
Sbjct: 56  YGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQ 113

Query: 787 FTNVPERTQIDVGRIPLQRLKLKCIFCRHR---VKRVSGACIQCSYGRCPASFHVTCAHA 843
           F NV     I +  +P  R    C  C  +    K  +GAC+ C+   C  +FHVTCA  
Sbjct: 114 FANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQF 173

Query: 844 AGVLMEPD 851
           AG+L E +
Sbjct: 174 AGLLCEEE 181


>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform a [Homo sapiens]
          Length = 1027

 Score =  104 bits (259), Expect = 5e-22
 Identities = 65/188 (34%), Positives = 92/188 (48%), Gaps = 20/188 (10%)

Query: 673 DEVVTSEGKTKPLIPEM---CFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASC 729
           D  V+ E +    + EM   C + S+E      P  + +  G         C V VH +C
Sbjct: 5   DRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHG---------CSVAVHQAC 55

Query: 730 YGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVR 786
           YGI   ++  G W C +C+    A    C LC  + GALK+T N  WAHV+CA+ +PEV+
Sbjct: 56  YGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQ 113

Query: 787 FTNVPERTQIDVGRIPLQRLKLKCIFCRHR---VKRVSGACIQCSYGRCPASFHVTCAHA 843
           F NV     I +  +P  R    C  C  +    K  +GAC+ C+   C  +FHVTCA  
Sbjct: 114 FANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQF 173

Query: 844 AGVLMEPD 851
           AG+L E +
Sbjct: 174 AGLLCEEE 181


>gi|117190334 PHD finger protein 16 [Homo sapiens]
          Length = 823

 Score =  102 bits (253), Expect = 2e-21
 Identities = 62/145 (42%), Positives = 82/145 (56%), Gaps = 13/145 (8%)

Query: 709 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 767
           E+G  ++  C KC V VH +CYGI   ++ +G WLC  C    +  +C LC  +GGALK 
Sbjct: 212 EEGNDMVF-CDKCNVCVHQACYGIL--KVPEGSWLCRSCVLGIYP-QCVLCPKKGGALKT 267

Query: 768 TKNN-KWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKLKCIFCRHRVKRVSGAC 824
           TK   KWAHV CA+ +PEV     PER +    +  IP  R  L C  C+ +    +GAC
Sbjct: 268 TKTGTKWAHVSCALWIPEVSIA-CPERMEPITKISHIPPSRWALVCNLCKLK----TGAC 322

Query: 825 IQCSYGRCPASFHVTCAHAAGVLME 849
           IQCS   C  +FHVTCA   G+ M+
Sbjct: 323 IQCSIKSCITAFHVTCAFEHGLEMK 347



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 39/175 (22%), Positives = 68/175 (38%), Gaps = 35/175 (20%)

Query: 430 EEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAY---RSVPSISSEADD 486
           +EES  +RM++  +L   ++   N C   S  E +K   +K         V  ++ E D 
Sbjct: 461 KEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDA 520

Query: 487 SIPLSSGYE--------------KPEKSDPSEL--------SWPKSPESCSSVAESNGVL 524
            +PL++  E              K  KS P +           P SP+S SSV     + 
Sbjct: 521 GLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQ 580

Query: 525 TEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSIAEGEN---KTSKSWRHPLS 576
              E  ++ +          P  P   +N+  + S++   +   ++S +WR P S
Sbjct: 581 VPQESLEMRTK-------SYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSS 628


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,402,699
Number of Sequences: 37866
Number of extensions: 2165272
Number of successful extensions: 7370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 229
Number of HSP's that attempted gapping in prelim test: 6854
Number of HSP's gapped (non-prelim): 659
length of query: 1056
length of database: 18,247,518
effective HSP length: 113
effective length of query: 943
effective length of database: 13,968,660
effective search space: 13172446380
effective search space used: 13172446380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.