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Search of human proteins with 14249622
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14249622 ajuba isoform 1 [Homo sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14249622 ajuba isoform 1 [Homo sapiens] 1143 0.0
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens] 349 3e-96
gi|7657307 LIM domains containing 1 [Homo sapiens] 332 5e-91
gi|37675280 ajuba isoform 2 [Homo sapiens] 281 1e-75
gi|5031887 LIM domain containing preferred translocation partner... 233 3e-61
gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens] 224 2e-58
gi|58530845 zyxin [Homo sapiens] 200 3e-51
gi|4508047 zyxin [Homo sapiens] 200 3e-51
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 172 9e-43
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens] 171 2e-42
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 107 4e-23
gi|221316659 leupaxin isoform 1 [Homo sapiens] 97 3e-20
gi|4758670 leupaxin isoform 2 [Homo sapiens] 97 3e-20
gi|170932516 paxillin isoform 2 [Homo sapiens] 93 7e-19
gi|170932518 paxillin isoform 3 [Homo sapiens] 92 9e-19
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 90 5e-18
gi|170932514 paxillin isoform 1 [Homo sapiens] 90 6e-18
gi|109638745 transforming growth factor beta 1 induced transcrip... 88 2e-17
gi|21361591 transforming growth factor beta 1 induced transcript... 88 2e-17
gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ... 86 9e-17
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 82 2e-15
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 82 2e-15
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 82 2e-15
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 82 2e-15
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 82 2e-15
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 81 2e-15
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 81 2e-15
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 81 2e-15
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 80 4e-15
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 79 1e-14
>gi|14249622 ajuba isoform 1 [Homo sapiens]
Length = 538
Score = 1143 bits (2957), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MERLGEKASRLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEP 60
MERLGEKASRLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEP
Sbjct: 1 MERLGEKASRLLEKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEP 60
Query: 61 LEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSP 120
LEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSP
Sbjct: 61 LEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSP 120
Query: 121 RSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAG 180
RSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAG
Sbjct: 121 RSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAG 180
Query: 181 PCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGA 240
PCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGA
Sbjct: 181 PCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGA 240
Query: 241 LAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGE 300
LAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGE
Sbjct: 241 LAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGE 300
Query: 301 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYH 360
PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYH
Sbjct: 301 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYH 360
Query: 361 TQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGK 420
TQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGK
Sbjct: 361 TQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGK 420
Query: 421 SYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIV 480
SYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIV
Sbjct: 421 SYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIV 480
Query: 481 RVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI 538
RVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI
Sbjct: 481 RVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI 538
>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
Length = 430
Score = 349 bits (896), Expect = 3e-96
Identities = 217/498 (43%), Positives = 252/498 (50%), Gaps = 103/498 (20%)
Query: 40 GLGGPRKSGPRGATGGPGDE--PLEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTR 97
G G P + G RG GPGDE P R +GS E G R GP R
Sbjct: 26 GCGSPGR-GRRGPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRGER-------GP---R 74
Query: 98 ALPLPQSLPPDFRLEPTAPALSPRSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRP 157
+P+ PA SPR+S A S DG G GG
Sbjct: 75 RAAVPEL--------SAQPAGSPRASLAGS-----------------DGGGGGG------ 103
Query: 158 CSNRTSGISMGYDQRHGSPLPAGPCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQ 217
S R+SGIS+GYDQRHGS P +G G PS
Sbjct: 104 -SARSSGISLGYDQRHGS-----------PRSGRSDPRPGPGPPSV-------------- 137
Query: 218 RPAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQ 277
G S S + GS GA A A P R +P A A +
Sbjct: 138 -----GSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEP-----------AGPAPFP 181
Query: 278 DELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGT 337
L GRE G PS E E RA E DYFG
Sbjct: 182 LPALPL------PPGREGG---------PSAAERRLEALTRELERAL--EARTARDYFGI 224
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
CIKC GIYG ACQA+ SLYHT CF C SCGR LR KAFY+V VYC+ED+L+SGFQ
Sbjct: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ A+KC VCGHLI+E ILQA+GKSYHPGCFRC VCN+CLDG+PFTVD N +YCV DYH
Sbjct: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHT 344
Query: 458 NYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGH 517
+APKCA+C +PILP++GCE +RV+SMDRDYH CYHCEDC +QLS EEG C+PL GH
Sbjct: 345 VFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGH 404
Query: 518 LLCHGCHMQRLNARQPPA 535
LLC CH++RL P+
Sbjct: 405 LLCRRCHLRRLQPGPLPS 422
Score = 36.6 bits (83), Expect = 0.060
Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 17/98 (17%)
Query: 22 SSRSGSDGTPGPGKGRLSGLG-------GPRKSGPRGATGGPGDEPLEPAREQGSLDAER 74
+S +GSDG G G R SG+ G +SG GPG + AR S R
Sbjct: 91 ASLAGSDGGGGGGSARSSGISLGYDQRHGSPRSGRSDPRPGPGPPSVGSARSSVSSLGSR 150
Query: 75 NQRGSFEAPRYEGSFPA----------GPPPTRALPLP 102
G++ G+ PA P P ALPLP
Sbjct: 151 GSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALPLP 188
>gi|7657307 LIM domains containing 1 [Homo sapiens]
Length = 676
Score = 332 bits (851), Expect = 5e-91
Identities = 183/439 (41%), Positives = 245/439 (55%), Gaps = 48/439 (10%)
Query: 133 SKPSSPRGSLLLDGAGAGGAGGSRPC-------SNRTSGISMGYDQRHGSPLPAGPCLFG 185
S S GSL +G GG +P S R S + +G+P GP
Sbjct: 235 SSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQRVSPGLPSPNLENGAPA-VGPVQPR 293
Query: 186 PPLAGAPAGYS---PGGVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGALA 242
P AP S GG+P + L + + ++ Q P + S A +
Sbjct: 294 TPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSK--PNVDPQPWFQDGPKSYLSSSAPS 351
Query: 243 GAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPS 302
+ G G ++GA PG G D G + T+L+ + T E + P
Sbjct: 352 SSPAGLDG--SQQGAVPGLGPKPGCTDLGTGPKLSP--TSLVHPVMSTLP-ELSCKEGPL 406
Query: 303 GIEPSG------LEEPPGPFV--------------PEAARARM--------REPEA--RE 332
G G L+ P P V P AA ++ RE +A +
Sbjct: 407 GWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLEALTQRLEREMDAHPKA 466
Query: 333 DYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYL 392
DYFG C+KC+KG++G ACQA+ +LYH CF C +C R LR KAFY VNG V+CEED+L
Sbjct: 467 DYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFL 526
Query: 393 FSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCV 452
+SGFQ++A++C +CGHLI++ ILQA+GKSYHPGCFRC++CN+CLDG+PFTVD N++YCV
Sbjct: 527 YSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCV 586
Query: 453 TDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCF 512
DYHK APKCAACG PILP EG ++ +RV+SMDRDYH ECYHCEDC ++L+DE+G C+
Sbjct: 587 RDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCY 646
Query: 513 PLDGHLLCHGCHMQRLNAR 531
PL+ HL CH CH++RL R
Sbjct: 647 PLEDHLFCHSCHVKRLEKR 665
Score = 29.3 bits (64), Expect = 9.5
Identities = 38/147 (25%), Positives = 56/147 (38%), Gaps = 12/147 (8%)
Query: 17 RRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEPLEPAREQGSLDAERNQ 76
R+ SS S+G+ G G+ SG+GG P G + + P +L+
Sbjct: 230 RQLSLSSSRSSEGSLG---GQNSGIGGRSSEKPTGLWSTASSQRVSPGLPSPNLENGAPA 286
Query: 77 RGSFEAPRYEGSFPAGPPPTRALPLPQS---LPPDFRLEPTAPALSPRSSF---ASSSAS 130
G + S P R LP+S L + + P + P+ F S S
Sbjct: 287 VGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLS 346
Query: 131 DASKPSSPRGSLLLDGAGAGGAGGSRP 157
++ SSP G LDG+ G G P
Sbjct: 347 SSAPSSSPAG---LDGSQQGAVPGLGP 370
>gi|37675280 ajuba isoform 2 [Homo sapiens]
Length = 121
Score = 281 bits (718), Expect = 1e-75
Identities = 121/121 (100%), Positives = 121/121 (100%)
Query: 418 MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE 477
MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE
Sbjct: 1 MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE 60
Query: 478 DIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANY 537
DIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANY
Sbjct: 61 DIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANY 120
Query: 538 I 538
I
Sbjct: 121 I 121
>gi|5031887 LIM domain containing preferred translocation partner in
lipoma [Homo sapiens]
Length = 612
Score = 233 bits (595), Expect = 3e-61
Identities = 145/448 (32%), Positives = 212/448 (47%), Gaps = 49/448 (10%)
Query: 100 PLPQSLPPDFRLEPTAP--ALSPRSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRP 157
P PQ+ P P AP L P+ +S + AS S P ++ + A + P
Sbjct: 184 PAPQAGPI-----PVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAP 238
Query: 158 CSNRTSGIS-MGYDQRHGSPLPAGPCLFGPPLAGA-------PAGYSPGGVPSAYPELHA 209
S + G GY+ + P+P P G P G P P
Sbjct: 239 SSGQIYGSGPQGYNTQ---PVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGR 295
Query: 210 ALDRLYAQRPAGFGCQESRHSYPPALGSPG---------ALAGAGVGAAGPLERRGAQPG 260
+ YA P G+G R+ P G G G G P PG
Sbjct: 296 YYEGYYAAGP-GYG---GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNP-------PG 344
Query: 261 RHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEA 320
+ VTG + D ++A + G +G G PS + PS E + +
Sbjct: 345 MYPVTGPKKTYI----TDPVSAPCAPPLQPKGGHSGQLG-PSSVAPSFRPEDELEHLTKK 399
Query: 321 ARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYS 380
M P A ++YFG C +C + + G+ C A+D ++H CF C C LR + FY+
Sbjct: 400 MLYDMENPPA-DEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYA 458
Query: 381 VNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIP 440
V YCE Y+ E+C VC I+E+IL+A GK+YHP CF C++C++ LDGIP
Sbjct: 459 VEKKAYCEPCYI-----NTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIP 513
Query: 441 FTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCR 500
FTVD ++C+ D+HK +AP+C+ C +PI+P+ G E+ VR++++DRD+H CY CEDC
Sbjct: 514 FTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCG 573
Query: 501 MQLSDEEGCCCFPLDGHLLCHGCHMQRL 528
LS+ + C+PLDGH+LC C+ R+
Sbjct: 574 GLLSEGDNQGCYPLDGHILCKTCNSARI 601
>gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]
Length = 476
Score = 224 bits (571), Expect = 2e-58
Identities = 136/365 (37%), Positives = 189/365 (51%), Gaps = 52/365 (14%)
Query: 175 SPLPAGPCLFGPPLAGAPAGYSPGGVPS--AYPELHAALDRLYAQRPAGFGCQESRHSYP 232
SPLPA P +G P PA Y+ P+ A+P + AQ G G P
Sbjct: 142 SPLPASP--YGGP---TPASYTTASTPAGPAFP-----VQVKVAQPVRGCG--------P 183
Query: 233 PALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYG-----DCAVGARYQDELTALLRLT 287
P G+ A +G G PL PGR V G G + GA+ +
Sbjct: 184 PRRGASQA-SGPLPGPHFPL------PGRGEVWGPGYRSQREPGPGAKEE---------A 227
Query: 288 VGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARAR---MREPEAREDYFGTCIKCNKG 344
G G RG G + L +PP + + M P + E YFG C C +
Sbjct: 228 AGVSGPAGRGRGGEHGPQVP-LSQPPEDELDRLTKKLVHDMNHPPSGE-YFGQCGGCGED 285
Query: 345 IYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCC 404
+ G ALD ++H CFVC +C LR + FY+V YCE Y+ + EKC
Sbjct: 286 VVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVAT-----LEKCA 340
Query: 405 VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCA 464
C IL++IL+AMGK+YHPGCF C+VC++ LDGIPFTVD ++Q++C+ D+H+ +AP+C+
Sbjct: 341 TCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCS 400
Query: 465 ACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGC-CCFPLDGHLLCHGC 523
CG I+P G E+ VR++++DR +H CY CE+C + LS E C C+PLDGH+LC C
Sbjct: 401 VCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKAC 460
Query: 524 HMQRL 528
R+
Sbjct: 461 SAWRI 465
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 200 bits (508), Expect = 3e-51
Identities = 167/576 (28%), Positives = 236/576 (40%), Gaps = 112/576 (19%)
Query: 18 RKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEPLEPAREQGSLD-AERNQ 76
R G+S + G GR+ + P P D PL P G D AE
Sbjct: 40 RPGDSEPPPAPGAQRAQMGRVGEIPPPP----------PEDFPLPPPPLAGDGDDAEGAL 89
Query: 77 RGSFEAPR--YEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPAL---SPRSSFAS----- 126
G+F P E SFP P P P PP+ P AP PR +S
Sbjct: 90 GGAFPPPPPPIEESFPPAPLEEEIFPSPPP-PPEEEGGPEAPIPPPPQPREKVSSIDLEI 148
Query: 127 ---SSASDASKPSSPRGSLLLDG-----------------AGAGGAGGSRPCSNRTSGIS 166
SS D + P + + G AGG P + +S
Sbjct: 149 DSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQP 208
Query: 167 M--------GYDQRHGSPLP-------------AGPCLFGPPLAGAPAGYSPGGVPS--- 202
+ Q H P P P P SP P
Sbjct: 209 LPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSP 268
Query: 203 AYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGALAGAGVGAAGP--------LER 254
P+ + P G G Q ++ LG P AL+ AG G+ P E+
Sbjct: 269 VTPKFTPVASKFSPGAPGGSGSQPNQK-----LGHPEALS-AGTGSPQPPSFTYAQQREK 322
Query: 255 RGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPG 314
Q +H V A+ Q+++ R GA G + E LE+
Sbjct: 323 PRVQEKQHPVPP------PAQNQNQV------------RSPGAPGPLTLKEVEELEQLTQ 364
Query: 315 PFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLR 374
+ + + + E C +C++ + A +AL L+H CF C C + L+
Sbjct: 365 QLMQDMEHPQRQNVAVNE----LCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ 420
Query: 375 CKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK 434
+ FYS+ G+ YCE Y + EKC CG I +++L+A GK+YHP CF C+VC +
Sbjct: 421 GQQFYSLEGAPYCEGCYT-----DTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCAR 475
Query: 435 CLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECY 494
L+G F VD +N+ +CV DYHK YAP+C+ C +PI+P G ++ VRV+++D+++H +CY
Sbjct: 476 PLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCY 535
Query: 495 HCEDCRMQLS---DEEGCCCFPLDGHLLCHGCHMQR 527
CEDC LS D+ G CFPLDGH+LC CH R
Sbjct: 536 KCEDCGKPLSIEADDNG--CFPLDGHVLCRKCHTAR 569
Score = 35.4 bits (80), Expect = 0.13
Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
Query: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522
C C QP+ ++ V ++ + +H C+ C C QL ++ + L+G C G
Sbjct: 384 CGRCHQPLARAQPA-----VRALGQLFHIACFTCHQCAQQLQGQQ---FYSLEGAPYCEG 435
Query: 523 CHMQRL 528
C+ L
Sbjct: 436 CYTDTL 441
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 200 bits (508), Expect = 3e-51
Identities = 167/576 (28%), Positives = 236/576 (40%), Gaps = 112/576 (19%)
Query: 18 RKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGATGGPGDEPLEPAREQGSLD-AERNQ 76
R G+S + G GR+ + P P D PL P G D AE
Sbjct: 40 RPGDSEPPPAPGAQRAQMGRVGEIPPPP----------PEDFPLPPPPLAGDGDDAEGAL 89
Query: 77 RGSFEAPR--YEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPAL---SPRSSFAS----- 126
G+F P E SFP P P P PP+ P AP PR +S
Sbjct: 90 GGAFPPPPPPIEESFPPAPLEEEIFPSPPP-PPEEEGGPEAPIPPPPQPREKVSSIDLEI 148
Query: 127 ---SSASDASKPSSPRGSLLLDG-----------------AGAGGAGGSRPCSNRTSGIS 166
SS D + P + + G AGG P + +S
Sbjct: 149 DSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQP 208
Query: 167 M--------GYDQRHGSPLP-------------AGPCLFGPPLAGAPAGYSPGGVPS--- 202
+ Q H P P P P SP P
Sbjct: 209 LPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSP 268
Query: 203 AYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGALAGAGVGAAGP--------LER 254
P+ + P G G Q ++ LG P AL+ AG G+ P E+
Sbjct: 269 VTPKFTPVASKFSPGAPGGSGSQPNQK-----LGHPEALS-AGTGSPQPPSFTYAQQREK 322
Query: 255 RGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPG 314
Q +H V A+ Q+++ R GA G + E LE+
Sbjct: 323 PRVQEKQHPVPP------PAQNQNQV------------RSPGAPGPLTLKEVEELEQLTQ 364
Query: 315 PFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLR 374
+ + + + E C +C++ + A +AL L+H CF C C + L+
Sbjct: 365 QLMQDMEHPQRQNVAVNE----LCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ 420
Query: 375 CKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK 434
+ FYS+ G+ YCE Y + EKC CG I +++L+A GK+YHP CF C+VC +
Sbjct: 421 GQQFYSLEGAPYCEGCYT-----DTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCAR 475
Query: 435 CLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECY 494
L+G F VD +N+ +CV DYHK YAP+C+ C +PI+P G ++ VRV+++D+++H +CY
Sbjct: 476 PLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCY 535
Query: 495 HCEDCRMQLS---DEEGCCCFPLDGHLLCHGCHMQR 527
CEDC LS D+ G CFPLDGH+LC CH R
Sbjct: 536 KCEDCGKPLSIEADDNG--CFPLDGHVLCRKCHTAR 569
Score = 35.4 bits (80), Expect = 0.13
Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
Query: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522
C C QP+ ++ V ++ + +H C+ C C QL ++ + L+G C G
Sbjct: 384 CGRCHQPLARAQPA-----VRALGQLFHIACFTCHQCAQQLQGQQ---FYSLEGAPYCEG 435
Query: 523 CHMQRL 528
C+ L
Sbjct: 436 CYTDTL 441
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 172 bits (435), Expect = 9e-43
Identities = 82/235 (34%), Positives = 129/235 (54%), Gaps = 21/235 (8%)
Query: 296 GARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQAL 355
G +P + P E PP P EP + C C+K + + A +A+
Sbjct: 151 GPSVQPGPLRPMEEELPPPP----------AEPVEKGASTDICAFCHKTVSPRELAVEAM 200
Query: 356 DSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKIL 415
YH QCF C +C R L ++FY +G CE Y Q+ E+C CG ++ + I+
Sbjct: 201 KRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHII 255
Query: 416 QAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEG 475
+A+G+++HP CF C+ C +C+ F + N+VYC+ D+++ +AP C+ C PI+P +G
Sbjct: 256 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG 315
Query: 476 CEDIVRVISMDRDYHFECYHCEDCRMQLSDE---EGCCCFPLDGHLLCHGCHMQR 527
+D ++ M R++H CY CEDCR+ LS E +G C+PL+ HL C CH++R
Sbjct: 316 -KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQG--CYPLNNHLFCKPCHVKR 367
Score = 43.5 bits (101), Expect = 5e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522
CA C + + P E + V +M R YH +C+ C CR QL+ G + DG LC
Sbjct: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 234
Query: 523 CHMQRL 528
C+ L
Sbjct: 235 CYQDTL 240
>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
Length = 276
Score = 171 bits (433), Expect = 2e-42
Identities = 83/232 (35%), Positives = 129/232 (55%), Gaps = 14/232 (6%)
Query: 301 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFG--TCIKCNKGIYGQSNACQALDSL 358
P +GL P P+ RA P A F C C+K + + A +A+
Sbjct: 48 PMKTPEAGLAGRPSPWTTPG-RAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQ 106
Query: 359 YHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAM 418
YH QCF C +C R L ++FY +G CE Y Q+ E+C CG ++ + I++A+
Sbjct: 107 YHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRAL 161
Query: 419 GKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCED 478
G+++HP CF C+ C +C+ F + N+VYC+ D+++ +AP C+ C PI+P +G +D
Sbjct: 162 GQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-KD 220
Query: 479 IVRVISMDRDYHFECYHCEDCRMQLSDE---EGCCCFPLDGHLLCHGCHMQR 527
++ M R++H CY CEDCR+ LS E +G C+PL+ HL C CH++R
Sbjct: 221 AFKIECMGRNFHENCYRCEDCRILLSVEPTDQG--CYPLNNHLFCKPCHVKR 270
Score = 43.5 bits (101), Expect = 5e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522
CA C + + P E + V +M R YH +C+ C CR QL+ G + DG LC
Sbjct: 86 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 137
Query: 523 CHMQRL 528
C+ L
Sbjct: 138 CYQDTL 143
>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
Length = 374
Score = 107 bits (266), Expect = 4e-23
Identities = 52/172 (30%), Positives = 84/172 (48%), Gaps = 15/172 (8%)
Query: 296 GARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQAL 355
G +P + P E PP P EP + C C+K + + A +A+
Sbjct: 151 GPSVQPGPLRPMEEELPPPP----------AEPVEKGASTDICAFCHKTVSPRELAVEAM 200
Query: 356 DSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKIL 415
YH QCF C +C R L ++FY +G CE Y Q+ E+C CG ++ + I+
Sbjct: 201 KRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHII 255
Query: 416 QAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACG 467
+A+G+++HP CF C+ C +C+ F + N+VYC+ D+++ C G
Sbjct: 256 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTGWG 307
Score = 47.4 bits (111), Expect = 3e-05
Identities = 31/110 (28%), Positives = 46/110 (41%), Gaps = 19/110 (17%)
Query: 403 CCVCGHLIL--EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYA 460
C C + E ++AM + YH CF C C + L G F Y K+
Sbjct: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSF-------------YQKDGR 229
Query: 461 PKCAACGQPILPSEG-CEDIVR---VISMDRDYHFECYHCEDCRMQLSDE 506
P C C Q L G C ++VR + ++ + +H C+ C C + DE
Sbjct: 230 PLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDE 279
Score = 43.5 bits (101), Expect = 5e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522
CA C + + P E + V +M R YH +C+ C CR QL+ G + DG LC
Sbjct: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 234
Query: 523 CHMQRL 528
C+ L
Sbjct: 235 CYQDTL 240
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 97.4 bits (241), Expect = 3e-20
Identities = 61/200 (30%), Positives = 87/200 (43%), Gaps = 29/200 (14%)
Query: 336 GTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSG 395
G C C K I G+ AL +H + FVC C + F+ +G YC DY
Sbjct: 155 GHCASCQKPIAGK--VIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDY---- 208
Query: 396 FQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDY 455
Q + +C C IL+K+L AM +++HP F C C + F + + YC D+
Sbjct: 209 HQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFH-EKDKKPYCRKDF 267
Query: 456 HKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLD 515
++PKC C +P+L + + +MD +H EC+ C DC S F LD
Sbjct: 268 LAMFSPKCGGCNRPVLEN-------YLSAMDTVWHPECFVCGDCFTSFSTGS---FFELD 317
Query: 516 GH------------LLCHGC 523
G LCHGC
Sbjct: 318 GRPFCELHYHHRRGTLCHGC 337
Score = 72.0 bits (175), Expect = 1e-12
Identities = 44/151 (29%), Positives = 64/151 (42%), Gaps = 12/151 (7%)
Query: 354 ALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEK 413
A++ +H + F C CG + F+ + YC +D+L + KC C +LE
Sbjct: 230 AMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAM----FSPKCGGCNRPVLEN 285
Query: 414 ILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPS 473
L AM +HP CF C C F + + +C YH C CGQPI +
Sbjct: 286 YLSAMDTVWHPECFVCGDCFTSFSTGSF-FELDGRPFCELHYHHRRGTLCHGCGQPI--T 342
Query: 474 EGCEDIVRVISMDRDYHFECYHCEDCRMQLS 504
C + +M +H E + C C QLS
Sbjct: 343 GRC-----ISAMGYKFHPEHFVCAFCLTQLS 368
Score = 63.5 bits (153), Expect = 5e-10
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 11/146 (7%)
Query: 316 FVPEAARARMREPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGR 371
F E + ++P R+D+ C CN+ + N A+D+++H +CFVC C
Sbjct: 249 FGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWHPECFVCGDCFT 306
Query: 372 TLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIV 431
+ +F+ ++G +CE Y C CG I + + AMG +HP F C
Sbjct: 307 SFSTGSFFELDGRPFCELHY----HHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAF 362
Query: 432 CNKCLDGIPFTVDFSNQVYCVTDYHK 457
C L F + +++ YC ++K
Sbjct: 363 CLTQLSKGIFR-EQNDKTYCQPCFNK 387
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 97.4 bits (241), Expect = 3e-20
Identities = 61/200 (30%), Positives = 87/200 (43%), Gaps = 29/200 (14%)
Query: 336 GTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSG 395
G C C K I G+ AL +H + FVC C + F+ +G YC DY
Sbjct: 150 GHCASCQKPIAGK--VIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDY---- 203
Query: 396 FQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDY 455
Q + +C C IL+K+L AM +++HP F C C + F + + YC D+
Sbjct: 204 HQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFH-EKDKKPYCRKDF 262
Query: 456 HKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLD 515
++PKC C +P+L + + +MD +H EC+ C DC S F LD
Sbjct: 263 LAMFSPKCGGCNRPVLEN-------YLSAMDTVWHPECFVCGDCFTSFSTGS---FFELD 312
Query: 516 GH------------LLCHGC 523
G LCHGC
Sbjct: 313 GRPFCELHYHHRRGTLCHGC 332
Score = 72.0 bits (175), Expect = 1e-12
Identities = 44/151 (29%), Positives = 64/151 (42%), Gaps = 12/151 (7%)
Query: 354 ALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEK 413
A++ +H + F C CG + F+ + YC +D+L + KC C +LE
Sbjct: 225 AMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAM----FSPKCGGCNRPVLEN 280
Query: 414 ILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPS 473
L AM +HP CF C C F + + +C YH C CGQPI +
Sbjct: 281 YLSAMDTVWHPECFVCGDCFTSFSTGSF-FELDGRPFCELHYHHRRGTLCHGCGQPI--T 337
Query: 474 EGCEDIVRVISMDRDYHFECYHCEDCRMQLS 504
C + +M +H E + C C QLS
Sbjct: 338 GRC-----ISAMGYKFHPEHFVCAFCLTQLS 363
Score = 63.5 bits (153), Expect = 5e-10
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 11/146 (7%)
Query: 316 FVPEAARARMREPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGR 371
F E + ++P R+D+ C CN+ + N A+D+++H +CFVC C
Sbjct: 244 FGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWHPECFVCGDCFT 301
Query: 372 TLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIV 431
+ +F+ ++G +CE Y C CG I + + AMG +HP F C
Sbjct: 302 SFSTGSFFELDGRPFCELHY----HHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAF 357
Query: 432 CNKCLDGIPFTVDFSNQVYCVTDYHK 457
C L F + +++ YC ++K
Sbjct: 358 CLTQLSKGIFR-EQNDKTYCQPCFNK 382
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 92.8 bits (229), Expect = 7e-19
Identities = 110/470 (23%), Positives = 178/470 (37%), Gaps = 88/470 (18%)
Query: 88 SFPAGPPPTRALPLPQSLPPDFRLEP-TAPALSPRSSFASSSASDASKPSSPRGSLLLDG 146
S+P G + + +P +PP E L P + SS+ + P+ S + G
Sbjct: 32 SYPTGNHTYQEIAVPPPVPPPPSSEALNGTILDPLDQWQPSSSRFIHQ--QPQSSSPVYG 89
Query: 147 AGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGPPLAGAPAGYSPGGVPSAYPE 206
+ A + S P + S S ++ H ++ P A SP + ++
Sbjct: 90 SSAKTSSVSNPQDSVGSPCSRVGEEEH---------VYSFPNKQKSAEPSPTVMSTSLGS 140
Query: 207 LHAALDRLYAQ------RPAGFGCQESRHSYP------PALGSPGALAGAGVGAAGPLER 254
+ LDRL + P GF E+ S P P G P + G G AGPL +
Sbjct: 141 NLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLG-GKAGPLTK 199
Query: 255 RGAQPGRHSVTGYGDCAVGAR-YQDELTALL---------------------------RL 286
+P R+ G D DEL + + R+
Sbjct: 200 E--KPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQTRI 257
Query: 287 TVGTGGREAG------------ARGEPSGIEPSGLEEPPGPFVPE---AARARMREPEAR 331
+ + RE A+G+ P G PG + + ++ + +
Sbjct: 258 SASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVA 317
Query: 332 EDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDY 391
G C C K I GQ A+ +H + FVC C + + F+ +G YCE+DY
Sbjct: 318 TVAKGVCGACKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
Query: 392 --LFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQV 449
LFS +C C IL+K++ A+ +++HP F C C F + +
Sbjct: 376 HNLFS------PRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKA 428
Query: 450 YCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDC 499
YC DY +APKC C + IL + + +++ +H EC+ C +C
Sbjct: 429 YCRKDYFDMFAPKCGGCARAILEN-------YISALNTLWHPECFVCREC 471
Score = 85.5 bits (210), Expect = 1e-16
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 26/186 (13%)
Query: 327 EPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVN 382
+P +DY C CN I + ALD +H + F C CG + F+ +
Sbjct: 368 QPYCEKDYHNLFSPRCYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 425
Query: 383 GSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFT 442
G YC +DY F A KC C ILE + A+ +HP CF VC +C PF
Sbjct: 426 GKAYCRKDY----FDMFAPKCGGCARAILENYISALNTLWHPECF---VCRECF--TPFV 476
Query: 443 ----VDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCED 498
+ Q YC YH+ C+ C +PI + C + +M + +H E + C
Sbjct: 477 NGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRC-----ITAMAKKFHPEHFVCAF 529
Query: 499 CRMQLS 504
C QL+
Sbjct: 530 CLKQLN 535
Score = 62.0 bits (149), Expect = 1e-09
Identities = 42/140 (30%), Positives = 62/140 (44%), Gaps = 11/140 (7%)
Query: 316 FVPEAARARMREPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGR 371
F PE + + R+DYF C C + I N AL++L+H +CFVC C
Sbjct: 416 FGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLWHPECFVCRECFT 473
Query: 372 TLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIV 431
+F+ +G YCE Y + C C I + + AM K +HP F C
Sbjct: 474 PFVNGSFFEHDGQPYCEVHY----HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAF 529
Query: 432 CNKCLDGIPFTVDFSNQVYC 451
C K L+ F + +++ YC
Sbjct: 530 CLKQLNKGTFK-EQNDKPYC 548
Score = 32.0 bits (71), Expect = 1.5
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYL 392
C C K I G+ A+ +H + FVC C + L F N YC+ +L
Sbjct: 501 CSGCQKPITGR--CITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 553
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 92.4 bits (228), Expect = 9e-19
Identities = 90/341 (26%), Positives = 138/341 (40%), Gaps = 38/341 (11%)
Query: 172 RHGSP-LPAGPCLFGPPLAGAPAGYSP-GGVPSAYPELHAALDRLYAQRP---AGFGCQE 226
+H P PA PPL GA SP GVP L L ++P G G ++
Sbjct: 23 QHNPPGFPADEANSSPPLPGA---LSPLYGVPETNSPLGGKAGPLTKEKPKRNGGRGLED 79
Query: 227 SRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYG---DCAVGARYQDELTAL 283
R S L + + V A + + P R + T + R DEL A
Sbjct: 80 VRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMAS 139
Query: 284 LRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPE---AARARMREPEAREDYFGTCIK 340
L + A+G+ P G PG + + ++ + + G C
Sbjct: 140 L------SDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGA 193
Query: 341 CNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDY--LFSGFQE 398
C K I GQ A+ +H + FVC C + + F+ +G YCE+DY LFS
Sbjct: 194 CKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFS---- 247
Query: 399 AAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKN 458
+C C IL+K++ A+ +++HP F C C F + + YC DY
Sbjct: 248 --PRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDM 304
Query: 459 YAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDC 499
+APKC C + IL + + +++ +H EC+ C +C
Sbjct: 305 FAPKCGGCARAILEN-------YISALNTLWHPECFVCREC 338
Score = 85.5 bits (210), Expect = 1e-16
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 26/186 (13%)
Query: 327 EPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVN 382
+P +DY C CN I + ALD +H + F C CG + F+ +
Sbjct: 235 QPYCEKDYHNLFSPRCYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 292
Query: 383 GSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFT 442
G YC +DY F A KC C ILE + A+ +HP CF VC +C PF
Sbjct: 293 GKAYCRKDY----FDMFAPKCGGCARAILENYISALNTLWHPECF---VCRECF--TPFV 343
Query: 443 ----VDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCED 498
+ Q YC YH+ C+ C +PI + C + +M + +H E + C
Sbjct: 344 NGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRC-----ITAMAKKFHPEHFVCAF 396
Query: 499 CRMQLS 504
C QL+
Sbjct: 397 CLKQLN 402
Score = 62.0 bits (149), Expect = 1e-09
Identities = 42/140 (30%), Positives = 62/140 (44%), Gaps = 11/140 (7%)
Query: 316 FVPEAARARMREPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGR 371
F PE + + R+DYF C C + I N AL++L+H +CFVC C
Sbjct: 283 FGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLWHPECFVCRECFT 340
Query: 372 TLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIV 431
+F+ +G YCE Y + C C I + + AM K +HP F C
Sbjct: 341 PFVNGSFFEHDGQPYCEVHY----HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAF 396
Query: 432 CNKCLDGIPFTVDFSNQVYC 451
C K L+ F + +++ YC
Sbjct: 397 CLKQLNKGTFK-EQNDKPYC 415
Score = 32.0 bits (71), Expect = 1.5
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYL 392
C C K I G+ A+ +H + FVC C + L F N YC+ +L
Sbjct: 368 CSGCQKPITGR--CITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 420
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 90.1 bits (222), Expect = 5e-18
Identities = 59/192 (30%), Positives = 87/192 (45%), Gaps = 19/192 (9%)
Query: 337 TCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGF 396
TC +C G + LYH QCFVC C + FY G YCE D F
Sbjct: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHD-----F 63
Query: 397 QEAAEKCC-VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDY 455
Q CC CG I+ ++++AM S+HP CFRC +C + L I F V + + C +
Sbjct: 64 QMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF-VKNAGRHLCRPCH 122
Query: 456 HKNYAPKCAACGQPILPSEGCEDIV---RVISMDRDYHFECYHCEDCRMQLSDEEGCCCF 512
++ K G+ I + C I+ +I + YH + ++C +C +L+ +
Sbjct: 123 NRE---KARGLGKYI--CQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTAD----AR 173
Query: 513 PLDGHLLCHGCH 524
L G L C CH
Sbjct: 174 ELKGELYCLPCH 185
Score = 55.1 bits (131), Expect = 2e-07
Identities = 53/193 (27%), Positives = 79/193 (40%), Gaps = 19/193 (9%)
Query: 316 FVPEAARARMREPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGR 371
FV A R R RE G C KC+ I Q + + YH F C +CG+
Sbjct: 109 FVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFK--NDPYHPDHFNCANCGK 166
Query: 372 TLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIV 431
L A + G +YC + G C C I +++ AMGK +H F C
Sbjct: 167 ELTADA-RELKGELYCLPCHDKMG----VPICGACRRPIEGRVVNAMGKQWHVEHFVCAK 221
Query: 432 CNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHF 491
C K G + YC T Y++ + C C + I EG D+V ++++ +
Sbjct: 222 CEKPFLGHRH-YERKGLAYCETHYNQLFGDVCFHCNRVI---EG--DVVS--ALNKAWCV 273
Query: 492 ECYHCEDCRMQLS 504
C+ C C +L+
Sbjct: 274 NCFACSTCNTKLT 286
Score = 52.4 bits (124), Expect = 1e-06
Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 6/120 (5%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ A+ +H + FVC C + Y G YCE Y Q
Sbjct: 193 CGACRRPIEGR--VVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYN----Q 246
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ C C +I ++ A+ K++ CF C CN L V+F + C Y K
Sbjct: 247 LFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 89.7 bits (221), Expect = 6e-18
Identities = 60/217 (27%), Positives = 98/217 (45%), Gaps = 24/217 (11%)
Query: 291 GGREAG---ARGEPSGIEPSGLEEPPGPFVPE---AARARMREPEAREDYFGTCIKCNKG 344
GG++ G A+G+ P G PG + + ++ + + G C C K
Sbjct: 305 GGQDEGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKP 364
Query: 345 IYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDY--LFSGFQEAAEK 402
I GQ A+ +H + FVC C + + F+ +G YCE+DY LFS +
Sbjct: 365 IAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFS------PR 416
Query: 403 CCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPK 462
C C IL+K++ A+ +++HP F C C F + + YC DY +APK
Sbjct: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPK 475
Query: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDC 499
C C + IL + + +++ +H EC+ C +C
Sbjct: 476 CGGCARAILEN-------YISALNTLWHPECFVCREC 505
Score = 85.5 bits (210), Expect = 1e-16
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 26/186 (13%)
Query: 327 EPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVN 382
+P +DY C CN I + ALD +H + F C CG + F+ +
Sbjct: 402 QPYCEKDYHNLFSPRCYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 459
Query: 383 GSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFT 442
G YC +DY F A KC C ILE + A+ +HP CF VC +C PF
Sbjct: 460 GKAYCRKDY----FDMFAPKCGGCARAILENYISALNTLWHPECF---VCRECF--TPFV 510
Query: 443 ----VDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCED 498
+ Q YC YH+ C+ C +PI + C + +M + +H E + C
Sbjct: 511 NGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRC-----ITAMAKKFHPEHFVCAF 563
Query: 499 CRMQLS 504
C QL+
Sbjct: 564 CLKQLN 569
Score = 62.0 bits (149), Expect = 1e-09
Identities = 42/140 (30%), Positives = 62/140 (44%), Gaps = 11/140 (7%)
Query: 316 FVPEAARARMREPEAREDYFGT----CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGR 371
F PE + + R+DYF C C + I N AL++L+H +CFVC C
Sbjct: 450 FGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLWHPECFVCRECFT 507
Query: 372 TLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIV 431
+F+ +G YCE Y + C C I + + AM K +HP F C
Sbjct: 508 PFVNGSFFEHDGQPYCEVHY----HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAF 563
Query: 432 CNKCLDGIPFTVDFSNQVYC 451
C K L+ F + +++ YC
Sbjct: 564 CLKQLNKGTFK-EQNDKPYC 582
Score = 32.0 bits (71), Expect = 1.5
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYL 392
C C K I G+ A+ +H + FVC C + L F N YC+ +L
Sbjct: 535 CSGCQKPITGR--CITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 587
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 87.8 bits (216), Expect = 2e-17
Identities = 65/225 (28%), Positives = 102/225 (45%), Gaps = 25/225 (11%)
Query: 299 GEPSGIEPSG---LEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQAL 355
G PS EP+G L+ G + +R R +A+ G C CNK I GQ AL
Sbjct: 191 GSPSPPEPTGKGSLDTMLGLLQSDLSR-RGVPTQAK----GLCGSCNKPIAGQ--VVTAL 243
Query: 356 DSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKIL 415
+H + FVC C L +F+ +G+ +C E Y F+ + +C C I K++
Sbjct: 244 GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECY----FERFSPRCGFCNQPIRHKMV 299
Query: 416 QAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEG 475
A+G +HP F C+ C + F + + YC D+ + +AP+C C PIL +
Sbjct: 300 TALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQGCQGPILDN-- 356
Query: 476 CEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLC 520
+ ++ +H +C+ C +C S G F +G LC
Sbjct: 357 -----YISALSALWHPDCFVCRECFAPFS---GGSFFEHEGRPLC 393
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/198 (27%), Positives = 80/198 (40%), Gaps = 23/198 (11%)
Query: 307 SGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVC 366
S E+ PF PE R + C CN+ I + AL + +H + F C
Sbjct: 265 SFFEKDGAPFCPECYFER---------FSPRCGFCNQPI--RHKMVTALGTHWHPEHFCC 313
Query: 367 CSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGC 426
SCG + F+ G YC D+L Q A +C C IL+ + A+ +HP C
Sbjct: 314 VSCGEPFGDEGFHEREGRPYCRRDFL----QLFAPRCQGCQGPILDNYISALSALWHPDC 369
Query: 427 FRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMD 486
F C C G F + + C +H CA CG P+ + C V ++
Sbjct: 370 FVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGSLCATCGLPV--TGRC-----VSALG 421
Query: 487 RDYHFECYHCEDCRMQLS 504
R +H + + C C L+
Sbjct: 422 RRFHPDHFTCTFCLRPLT 439
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 87.8 bits (216), Expect = 2e-17
Identities = 65/225 (28%), Positives = 102/225 (45%), Gaps = 25/225 (11%)
Query: 299 GEPSGIEPSG---LEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQAL 355
G PS EP+G L+ G + +R R +A+ G C CNK I GQ AL
Sbjct: 174 GSPSPPEPTGKGSLDTMLGLLQSDLSR-RGVPTQAK----GLCGSCNKPIAGQ--VVTAL 226
Query: 356 DSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKIL 415
+H + FVC C L +F+ +G+ +C E Y F+ + +C C I K++
Sbjct: 227 GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECY----FERFSPRCGFCNQPIRHKMV 282
Query: 416 QAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEG 475
A+G +HP F C+ C + F + + YC D+ + +AP+C C PIL +
Sbjct: 283 TALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQGCQGPILDN-- 339
Query: 476 CEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLC 520
+ ++ +H +C+ C +C S G F +G LC
Sbjct: 340 -----YISALSALWHPDCFVCRECFAPFS---GGSFFEHEGRPLC 376
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/198 (27%), Positives = 80/198 (40%), Gaps = 23/198 (11%)
Query: 307 SGLEEPPGPFVPEAARARMREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVC 366
S E+ PF PE R + C CN+ I + AL + +H + F C
Sbjct: 248 SFFEKDGAPFCPECYFER---------FSPRCGFCNQPI--RHKMVTALGTHWHPEHFCC 296
Query: 367 CSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGC 426
SCG + F+ G YC D+L Q A +C C IL+ + A+ +HP C
Sbjct: 297 VSCGEPFGDEGFHEREGRPYCRRDFL----QLFAPRCQGCQGPILDNYISALSALWHPDC 352
Query: 427 FRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMD 486
F C C G F + + C +H CA CG P+ + C V ++
Sbjct: 353 FVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGSLCATCGLPV--TGRC-----VSALG 404
Query: 487 RDYHFECYHCEDCRMQLS 504
R +H + + C C L+
Sbjct: 405 RRFHPDHFTCTFCLRPLT 422
>gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo
sapiens]
Length = 248
Score = 85.9 bits (211), Expect = 9e-17
Identities = 56/179 (31%), Positives = 82/179 (45%), Gaps = 18/179 (10%)
Query: 337 TCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGF 396
TC +C G + LYH QCFVC C + FY G YCE D F
Sbjct: 71 TCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHD-----F 125
Query: 397 QEAAEKCC-VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDY 455
Q CC CG I+ ++++AM S+HP CFRC +C + L I F V + + C +
Sbjct: 126 QMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF-VKNAGRHLCRPCH 184
Query: 456 HKNYAPKCAACGQPILPSEGCEDIV---RVISMDRDYHFECYHCEDCRMQLSDEEGCCC 511
++ K G+ I + C I+ +I + YH + ++C +C + SD C C
Sbjct: 185 NRE---KARGLGKYI--CQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSD---CRC 235
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 81.6 bits (200), Expect = 2e-15
Identities = 56/193 (29%), Positives = 80/193 (41%), Gaps = 23/193 (11%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C +C + LYH CFVC C R FY G YCE D FQ
Sbjct: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD-----FQ 91
Query: 398 EAAEKCC-VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
CC CG I+ ++++AM ++HPGCFRC +C+ L + F V + + C ++
Sbjct: 92 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGF-VKNAGRHLCRPCHN 150
Query: 457 KNYAPK-----CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCC 511
+ A C C I D ++ YH + ++C C +L+ E
Sbjct: 151 REKAKGLGKYICQRCHLVI-------DEQPLMFRSDAYHPDHFNCTHCGKELTAE----A 199
Query: 512 FPLDGHLLCHGCH 524
L G L C CH
Sbjct: 200 RELKGELYCLPCH 212
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ AL +H + FVC C + Y G YCE Y Q
Sbjct: 220 CGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYN----Q 273
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ C C H+I ++ A+ K++ CF C CN L V+F + C Y K
Sbjct: 274 LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/164 (26%), Positives = 70/164 (42%), Gaps = 14/164 (8%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ +A+++ +H CF C C L F G C + +
Sbjct: 98 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
Query: 398 EAAEKCCVCGHLIL-EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
+ C HL++ E+ L +YHP F C C K L + ++YC+ +
Sbjct: 156 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAE--ARELKGELYCLPCHD 213
Query: 457 KNYAPKCAACGQPILPSEGCEDIVRVI-SMDRDYHFECYHCEDC 499
K P C AC +PI EG RV+ ++ + +H E + C C
Sbjct: 214 KMGVPICGACRRPI---EG-----RVVNALGKQWHVEHFVCAKC 249
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 81.6 bits (200), Expect = 2e-15
Identities = 56/193 (29%), Positives = 80/193 (41%), Gaps = 23/193 (11%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C +C + LYH CFVC C R FY G YCE D FQ
Sbjct: 10 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD-----FQ 64
Query: 398 EAAEKCC-VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
CC CG I+ ++++AM ++HPGCFRC +C+ L + F V + + C ++
Sbjct: 65 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGF-VKNAGRHLCRPCHN 123
Query: 457 KNYAPK-----CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCC 511
+ A C C I D ++ YH + ++C C +L+ E
Sbjct: 124 REKAKGLGKYICQRCHLVI-------DEQPLMFRSDAYHPDHFNCTHCGKELTAE----A 172
Query: 512 FPLDGHLLCHGCH 524
L G L C CH
Sbjct: 173 RELKGELYCLPCH 185
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ AL +H + FVC C + Y G YCE Y Q
Sbjct: 193 CGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYN----Q 246
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ C C H+I ++ A+ K++ CF C CN L V+F + C Y K
Sbjct: 247 LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/164 (26%), Positives = 70/164 (42%), Gaps = 14/164 (8%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ +A+++ +H CF C C L F G C + +
Sbjct: 71 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 128
Query: 398 EAAEKCCVCGHLIL-EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
+ C HL++ E+ L +YHP F C C K L + ++YC+ +
Sbjct: 129 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAE--ARELKGELYCLPCHD 186
Query: 457 KNYAPKCAACGQPILPSEGCEDIVRVI-SMDRDYHFECYHCEDC 499
K P C AC +PI EG RV+ ++ + +H E + C C
Sbjct: 187 KMGVPICGACRRPI---EG-----RVVNALGKQWHVEHFVCAKC 222
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 81.6 bits (200), Expect = 2e-15
Identities = 56/193 (29%), Positives = 80/193 (41%), Gaps = 23/193 (11%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C +C + LYH CFVC C R FY G YCE D FQ
Sbjct: 15 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD-----FQ 69
Query: 398 EAAEKCC-VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
CC CG I+ ++++AM ++HPGCFRC +C+ L + F V + + C ++
Sbjct: 70 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGF-VKNAGRHLCRPCHN 128
Query: 457 KNYAPK-----CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCC 511
+ A C C I D ++ YH + ++C C +L+ E
Sbjct: 129 REKAKGLGKYICQRCHLVI-------DEQPLMFRSDAYHPDHFNCTHCGKELTAE----A 177
Query: 512 FPLDGHLLCHGCH 524
L G L C CH
Sbjct: 178 RELKGELYCLPCH 190
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ AL +H + FVC C + Y G YCE Y Q
Sbjct: 198 CGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYN----Q 251
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ C C H+I ++ A+ K++ CF C CN L V+F + C Y K
Sbjct: 252 LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/164 (26%), Positives = 70/164 (42%), Gaps = 14/164 (8%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ +A+++ +H CF C C L F G C + +
Sbjct: 76 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 133
Query: 398 EAAEKCCVCGHLIL-EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
+ C HL++ E+ L +YHP F C C K L + ++YC+ +
Sbjct: 134 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAE--ARELKGELYCLPCHD 191
Query: 457 KNYAPKCAACGQPILPSEGCEDIVRVI-SMDRDYHFECYHCEDC 499
K P C AC +PI EG RV+ ++ + +H E + C C
Sbjct: 192 KMGVPICGACRRPI---EG-----RVVNALGKQWHVEHFVCAKC 227
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 81.6 bits (200), Expect = 2e-15
Identities = 56/193 (29%), Positives = 80/193 (41%), Gaps = 23/193 (11%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C +C + LYH CFVC C R FY G YCE D FQ
Sbjct: 39 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD-----FQ 93
Query: 398 EAAEKCC-VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
CC CG I+ ++++AM ++HPGCFRC +C+ L + F V + + C ++
Sbjct: 94 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGF-VKNAGRHLCRPCHN 152
Query: 457 KNYAPK-----CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCC 511
+ A C C I D ++ YH + ++C C +L+ E
Sbjct: 153 REKAKGLGKYICQRCHLVI-------DEQPLMFRSDAYHPDHFNCTHCGKELTAE----A 201
Query: 512 FPLDGHLLCHGCH 524
L G L C CH
Sbjct: 202 RELKGELYCLPCH 214
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ AL +H + FVC C + Y G YCE Y Q
Sbjct: 222 CGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYN----Q 275
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ C C H+I ++ A+ K++ CF C CN L V+F + C Y K
Sbjct: 276 LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/164 (26%), Positives = 70/164 (42%), Gaps = 14/164 (8%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + I G+ +A+++ +H CF C C L F G C + +
Sbjct: 100 CGSCGEFIIGR--VIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 157
Query: 398 EAAEKCCVCGHLIL-EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYH 456
+ C HL++ E+ L +YHP F C C K L + ++YC+ +
Sbjct: 158 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAE--ARELKGELYCLPCHD 215
Query: 457 KNYAPKCAACGQPILPSEGCEDIVRVI-SMDRDYHFECYHCEDC 499
K P C AC +PI EG RV+ ++ + +H E + C C
Sbjct: 216 KMGVPICGACRRPI---EG-----RVVNALGKQWHVEHFVCAKC 251
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 81.6 bits (200), Expect = 2e-15
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 14/176 (7%)
Query: 334 YFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLF 393
+ TC +C + I S D +H CF CC C R+L + F + + C + Y
Sbjct: 36 FANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYC- 94
Query: 394 SGFQEAAEKCCVCGHLIL--EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYC 451
S F + +C CG ++ + L+ G+++H CF C C + L F D YC
Sbjct: 95 SAF---SSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPD-KGAHYC 150
Query: 452 VTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEE 507
V Y +AP+CA C + + V D+ +H EC C C+ L+ ++
Sbjct: 151 VPCYENKFAPRCARCSKTLTQG-------GVTYRDQPWHRECLVCTGCQTPLAGQQ 199
Score = 78.2 bits (191), Expect = 2e-14
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 13/187 (6%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C + + S + +H CF+C C + L ++F G+ YC Y
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYE----N 156
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ A +C C + + + + +H C C C L G FT YCV + +
Sbjct: 157 KFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFT-SRDEDPYCVACFGE 215
Query: 458 NYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDG- 516
+APKC++C +PI+ G + V DR +H C+ C C L + F DG
Sbjct: 216 LFAPKCSSCKRPIVGLGGGK---YVSFEDRHWHHNCFSCARCSTSLVGQG----FVPDGD 268
Query: 517 HLLCHGC 523
+LC GC
Sbjct: 269 QVLCQGC 275
Score = 61.6 bits (148), Expect = 2e-09
Identities = 40/171 (23%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Query: 361 TQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGK 420
++ F C C +L + + + YC Y + AE + GH E + +
Sbjct: 2 SESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYE--DR 59
Query: 421 SYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIV 480
+H GCFRC C + L PFT +++ C Y ++ +C+ACG+ ++P
Sbjct: 60 HFHEGCFRCCRCQRSLADEPFTCQ-DSELLCNDCYCSAFSSQCSACGETVMPGSR----- 113
Query: 481 RVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNAR 531
++ + +H C+ C C L P G C C+ + R
Sbjct: 114 KLEYGGQTWHEHCFLCSGCEQPLGSRS---FVPDKGAHYCVPCYENKFAPR 161
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 81.3 bits (199), Expect = 2e-15
Identities = 45/177 (25%), Positives = 75/177 (42%), Gaps = 20/177 (11%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C KC + G+ Q +H +CF C CG L F+ NG C DY +
Sbjct: 39 CHKCGEPCKGEVLRVQTKH--FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQ----R 92
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK--------CLDGIPFTVDFSNQV 449
+C CG + +++ A+GK+YHP CF C +C + +G Q
Sbjct: 93 MYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQP 152
Query: 450 YCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDE 506
+ ++ CA CG+ I + ++++D+ +H C+ C+ C L+ E
Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQA------LLALDKQWHLGCFKCKSCGKVLTGE 203
Score = 69.7 bits (169), Expect = 6e-12
Identities = 40/103 (38%), Positives = 52/103 (50%), Gaps = 10/103 (9%)
Query: 334 YFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDY-- 391
+ C C + I A ALD +H CF C SCG+ L + + S +G+ YCE+DY
Sbjct: 162 FSSNCAGCGRDIKN-GQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKDYQG 219
Query: 392 LFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK 434
LF KC C I K+L+A K YHP C RC CN+
Sbjct: 220 LFG------VKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256
Score = 66.6 bits (161), Expect = 5e-11
Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 18/180 (10%)
Query: 335 FGT-CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGS----VYCEE 389
+GT C C + + G+ AL YH CF C C R + NG C +
Sbjct: 94 YGTRCHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQ 151
Query: 390 DYLFSGFQEA-AEKCCVCGHLILE-KILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSN 447
S + + C CG I + L A+ K +H GCF+C C K L G + D
Sbjct: 152 PMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKD--G 209
Query: 448 QVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEE 507
YC DY + KC AC Q I + + D+ YH C C C ++ E
Sbjct: 210 APYCEKDYQGLFGVKCEACHQFITGKV-------LEAGDKHYHPSCARCSRCNQMFTEGE 262
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 81.3 bits (199), Expect = 2e-15
Identities = 45/177 (25%), Positives = 75/177 (42%), Gaps = 20/177 (11%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C KC + G+ Q +H +CF C CG L F+ NG C DY +
Sbjct: 39 CHKCGEPCKGEVLRVQTKH--FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQ----R 92
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK--------CLDGIPFTVDFSNQV 449
+C CG + +++ A+GK+YHP CF C +C + +G Q
Sbjct: 93 MYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQP 152
Query: 450 YCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDE 506
+ ++ CA CG+ I + ++++D+ +H C+ C+ C L+ E
Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQA------LLALDKQWHLGCFKCKSCGKVLTGE 203
Score = 69.7 bits (169), Expect = 6e-12
Identities = 40/103 (38%), Positives = 52/103 (50%), Gaps = 10/103 (9%)
Query: 334 YFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDY-- 391
+ C C + I A ALD +H CF C SCG+ L + + S +G+ YCE+DY
Sbjct: 162 FSSNCAGCGRDIKN-GQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKDYQG 219
Query: 392 LFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK 434
LF KC C I K+L+A K YHP C RC CN+
Sbjct: 220 LFG------VKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256
Score = 66.6 bits (161), Expect = 5e-11
Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 18/180 (10%)
Query: 335 FGT-CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGS----VYCEE 389
+GT C C + + G+ AL YH CF C C R + NG C +
Sbjct: 94 YGTRCHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQ 151
Query: 390 DYLFSGFQEA-AEKCCVCGHLILE-KILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSN 447
S + + C CG I + L A+ K +H GCF+C C K L G + D
Sbjct: 152 PMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKD--G 209
Query: 448 QVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEE 507
YC DY + KC AC Q I + + D+ YH C C C ++ E
Sbjct: 210 APYCEKDYQGLFGVKCEACHQFITGKV-------LEAGDKHYHPSCARCSRCNQMFTEGE 262
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 81.3 bits (199), Expect = 2e-15
Identities = 45/177 (25%), Positives = 75/177 (42%), Gaps = 20/177 (11%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C KC + G+ Q +H +CF C CG L F+ NG C DY +
Sbjct: 99 CHKCGEPCKGEVLRVQTKH--FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQ----R 152
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK--------CLDGIPFTVDFSNQV 449
+C CG + +++ A+GK+YHP CF C +C + +G Q
Sbjct: 153 MYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQP 212
Query: 450 YCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDE 506
+ ++ CA CG+ I + ++++D+ +H C+ C+ C L+ E
Sbjct: 213 MSSSPKETTFSSNCAGCGRDIKNGQA------LLALDKQWHLGCFKCKSCGKVLTGE 263
Score = 69.7 bits (169), Expect = 6e-12
Identities = 40/103 (38%), Positives = 52/103 (50%), Gaps = 10/103 (9%)
Query: 334 YFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDY-- 391
+ C C + I A ALD +H CF C SCG+ L + + S +G+ YCE+DY
Sbjct: 222 FSSNCAGCGRDIKN-GQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKDYQG 279
Query: 392 LFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNK 434
LF KC C I K+L+A K YHP C RC CN+
Sbjct: 280 LFG------VKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 316
Score = 66.6 bits (161), Expect = 5e-11
Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 18/180 (10%)
Query: 335 FGT-CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGS----VYCEE 389
+GT C C + + G+ AL YH CF C C R + NG C +
Sbjct: 154 YGTRCHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQ 211
Query: 390 DYLFSGFQEA-AEKCCVCGHLILE-KILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSN 447
S + + C CG I + L A+ K +H GCF+C C K L G + D
Sbjct: 212 PMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKD--G 269
Query: 448 QVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEE 507
YC DY + KC AC Q I + + D+ YH C C C ++ E
Sbjct: 270 APYCEKDYQGLFGVKCEACHQFITGKV-------LEAGDKHYHPSCARCSRCNQMFTEGE 322
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 80.5 bits (197), Expect = 4e-15
Identities = 98/430 (22%), Positives = 151/430 (35%), Gaps = 44/430 (10%)
Query: 79 SFEAPRYEGSFPAGPPPTRALPLPQSLPPDFRLEPTAPALSPRSSFASSSASDASKPSSP 138
S + P A PP A ++PA SPR +S S + A+ +
Sbjct: 320 SAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSPRPQASSYSPAVAASSAPA 379
Query: 139 RGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGPPLAGAPAGYSPG 198
+ +G A +P T+ I Q P+PA P +P Y+P
Sbjct: 380 THTSYSEGPAAPAP---KPRVVTTASIRPSVYQ----PVPASTYSPSPGANYSPTPYTPS 432
Query: 199 GVPSAYPELHAALDRLYAQRPAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQ 258
P+ P A Y P +Y P+ A + + GP E
Sbjct: 433 PAPAYTPSPAPA----YTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRP 488
Query: 259 PGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVP 318
P + A G T++ + T+ GG P GP VP
Sbjct: 489 PWVTDDSFSQKFAPGK----STTSISKQTLPRGGPAY---------------TPAGPQVP 529
Query: 319 EAARARMREPEAREDYFGT--CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCK 376
AR ++ E T C CN I G A+ +H + F C C +L
Sbjct: 530 PLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLV--AMGRSWHPEEFTCAYCKTSLADV 587
Query: 377 AFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCL 436
F +VYCE Y Q A C C I+ +++ A+ +++H CF C C K
Sbjct: 588 CFVEEQNNVYCERCY----EQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPF 643
Query: 437 DGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHC 496
F ++ + YC DY ++ KC C P+ E + + ++ +H C+ C
Sbjct: 644 GNSLFHME-DGEPYCEKDYINLFSTKCHGCDFPV---EAGDKFIE--ALGHTWHDTCFIC 697
Query: 497 EDCRMQLSDE 506
C + L +
Sbjct: 698 AVCHVNLEGQ 707
Score = 74.3 bits (181), Expect = 3e-13
Identities = 43/115 (37%), Positives = 60/115 (52%), Gaps = 13/115 (11%)
Query: 332 EDYFGT-CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEED 390
E +F C KCN I G+ AL +HT CFVC +C + F+ +G YCE+D
Sbjct: 603 EQFFAPLCAKCNTKIMGE--VMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD 660
Query: 391 Y--LFSGFQEAAEKCCVCGHLIL--EKILQAMGKSYHPGCFRCIVCNKCLDGIPF 441
Y LFS KC C + +K ++A+G ++H CF C VC+ L+G PF
Sbjct: 661 YINLFS------TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPF 709
Score = 57.4 bits (137), Expect = 3e-08
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 17/130 (13%)
Query: 403 CCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPK 462
C C ++I L AMG+S+HP F C C L + F V+ N VYC Y + +AP
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQFFAPL 609
Query: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCR-------MQLSDEEGCCCFPLD 515
CA C I+ + ++ + +H C+ C C+ + D E C
Sbjct: 610 CAKCNTKIMGEV-------MHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYI 662
Query: 516 G--HLLCHGC 523
CHGC
Sbjct: 663 NLFSTKCHGC 672
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 4/67 (5%)
Query: 327 EPEAREDY---FGT-CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVN 382
EP +DY F T C C+ + +AL +H CF+C C L + FYS
Sbjct: 654 EPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKK 713
Query: 383 GSVYCEE 389
C++
Sbjct: 714 DRPLCKK 720
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 79.0 bits (193), Expect = 1e-14
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C C K I + +++H CF C +C + + +F+ YC +
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE----T 156
Query: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
+ A+ C C I + + +H CF C+ C+K L G FT +Q YCV Y
Sbjct: 157 KFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTA-VEDQYYCVDCYKN 215
Query: 458 NYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDE 506
A KCA C PI +V + +H C+HC+ C + L+++
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAY--EGQSWHDYCFHCKKCSVNLANK 262
Score = 66.6 bits (161), Expect = 5e-11
Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 14/172 (8%)
Query: 337 TCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGF 396
TC++C K I S + +H CF C C L + F + + + C +
Sbjct: 39 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNK----CTT 94
Query: 397 QEAAEKCCVCGHLIL--EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTD 454
+E + KC C I+ ++ ++ G +H CF C C + + G YCVT
Sbjct: 95 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVI-GTGSFFPKGEDFYCVTC 153
Query: 455 YHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDE 506
+ +A C C + I + D+ +H +C+ C C +L+ +
Sbjct: 154 HETKFAKHCVKCNKAITSG-------GITYQDQPWHADCFVCVTCSKKLAGQ 198
Score = 61.2 bits (147), Expect = 2e-09
Identities = 39/119 (32%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
C+KCNK I S D +H CFVC +C + L + F +V YC + Y
Sbjct: 162 CVKCNKAI--TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK----N 215
Query: 398 EAAEKCCVCGHLIL-----EKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYC 451
A+KC C + I ++ G+S+H CF C C+ L F V QVYC
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRF-VFHQEQVYC 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.138 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,968,668
Number of Sequences: 37866
Number of extensions: 1939471
Number of successful extensions: 18501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 1199
Number of HSP's that attempted gapping in prelim test: 11262
Number of HSP's gapped (non-prelim): 5256
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.