BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14211837 cryptic [Homo sapiens] (223 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14211837 cryptic [Homo sapiens] 485 e-137 gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens] 482 e-136 gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens] 92 5e-19 gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens] 76 3e-14 gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens] 76 3e-14 gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 54 1e-07 gi|148833508 notch1 preproprotein [Homo sapiens] 49 3e-06 gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 48 8e-06 gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 44 1e-04 gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 44 1e-04 gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 44 1e-04 gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 44 1e-04 gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 44 1e-04 gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 43 2e-04 gi|110347437 latent transforming growth factor beta binding prot... 42 3e-04 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 42 5e-04 gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 42 5e-04 gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 42 5e-04 gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like... 41 7e-04 gi|110347412 latent transforming growth factor beta binding prot... 41 7e-04 gi|110347431 latent transforming growth factor beta binding prot... 41 7e-04 gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 41 0.001 gi|88702793 slit-like 2 [Homo sapiens] 41 0.001 gi|134244285 Notch homolog 3 [Homo sapiens] 40 0.001 gi|189491645 fibulin 7 isoform 1 [Homo sapiens] 40 0.002 gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 40 0.002 gi|122937283 6720455I24Rik homolog [Homo sapiens] 40 0.002 gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 40 0.002 gi|189491647 fibulin 7 isoform 2 [Homo sapiens] 40 0.002 gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 40 0.002 >gi|14211837 cryptic [Homo sapiens] Length = 223 Score = 485 bits (1248), Expect = e-137 Identities = 223/223 (100%), Positives = 223/223 (100%) Query: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE Sbjct: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60 Query: 61 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR Sbjct: 61 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120 Query: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL Sbjct: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180 Query: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL Sbjct: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223 >gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens] Length = 223 Score = 482 bits (1240), Expect = e-136 Identities = 222/223 (99%), Positives = 222/223 (99%) Query: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE Sbjct: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60 Query: 61 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120 VTGSAEGWGPEEPLPYS AFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR Sbjct: 61 VTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120 Query: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL Sbjct: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180 Query: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL Sbjct: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223 >gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens] Length = 188 Score = 91.7 bits (226), Expect = 5e-19 Identities = 36/69 (52%), Positives = 42/69 (60%) Query: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149 CC NGGTC+LGSFC CP F GR CEHD R+ CG++ H W + C LC+C G L C Sbjct: 82 CCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCF 141 Query: 150 PLQTPDRCD 158 P CD Sbjct: 142 PQAFLPGCD 150 >gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens] Length = 195 Score = 75.9 bits (185), Expect = 3e-14 Identities = 31/69 (44%), Positives = 38/69 (55%) Query: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149 CC NGGTC+LGSFC C F G CEH R+ CG++ H + C +C+C G L C Sbjct: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160 Query: 150 PLQTPDRCD 158 P CD Sbjct: 161 PQAFLPGCD 169 >gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens] Length = 195 Score = 75.9 bits (185), Expect = 3e-14 Identities = 31/69 (44%), Positives = 38/69 (55%) Query: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149 CC NGGTC+LGSFC C F G CEH R+ CG++ H + C +C+C G L C Sbjct: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160 Query: 150 PLQTPDRCD 158 P CD Sbjct: 161 PQAFLPGCD 169 >gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] Length = 763 Score = 53.5 bits (127), Expect = 1e-07 Identities = 27/59 (45%), Positives = 30/59 (50%), Gaps = 5/59 (8%) Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC 136 G G R C CR GGTCV + CVCP+ FTG +CE D EC H W AC Sbjct: 510 GNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKD--IDECALRTHTCWNDSAC 566 Score = 28.9 bits (63), Expect = 3.7 Identities = 11/25 (44%), Positives = 15/25 (60%), Gaps = 1/25 (4%) Query: 131 WTLRACHLCRCIFGALHCLPLQTPD 155 WT +C CRC+ G + C PL P+ Sbjct: 662 WT-HSCQQCRCLEGEVDCWPLTCPN 685 >gi|148833508 notch1 preproprotein [Homo sapiens] Length = 2555 Score = 48.9 bits (115), Expect = 3e-06 Identities = 25/54 (46%), Positives = 28/54 (51%), Gaps = 3/54 (5%) Query: 91 CRNGGTCVLG--SF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRC 141 C NGGTCV G SF C+CP FTG YC+HD + HG C RC Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRC 1045 Score = 42.0 bits (97), Expect = 4e-04 Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 10/50 (20%) Query: 83 GASARPRCCRNGGTCVLGS------FCVCPAHFTGRYCEHDQRRSECGAL 126 G +P C+NGGTC + S C CPA F G CE+D R CG+L Sbjct: 1310 GCKGKP--CKNGGTCAVASNTARGFICKCPAGFEGATCENDAR--TCGSL 1355 Score = 40.4 bits (93), Expect = 0.001 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 10/77 (12%) Query: 87 RPRCCRNGGTCVLG---SFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC---HLCR 140 RP C NGG+C G +FC C F G +CE D +GA C + C Sbjct: 912 RPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA-NCTDCVDSYTCT 970 Query: 141 CI--FGALHCLPLQTPD 155 C F +HC TPD Sbjct: 971 CPAGFSGIHC-ENNTPD 986 Score = 38.5 bits (88), Expect = 0.005 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 11/63 (17%) Query: 91 CRNGGTCVLGSF---CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH------LCRC 141 C+NGG CV G C CP +TG+YC D EC + + CH C C Sbjct: 266 CKNGGACVDGVNTYNCRCPPEWTGQYCTEDV--DECQLMPNACQNGGTCHNTHGGYNCVC 323 Query: 142 IFG 144 + G Sbjct: 324 VNG 326 Score = 37.7 bits (86), Expect = 0.008 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 7/64 (10%) Query: 74 LPYSRAFGEG--ASARPRCCRNGGTCVLG----SF-CVCPAHFTGRYCEHDQRRSECGAL 126 LPY+ A E A P CRNGG C SF CVCP + G+ CE D Sbjct: 819 LPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPC 878 Query: 127 EHGA 130 HGA Sbjct: 879 RHGA 882 Score = 37.7 bits (86), Expect = 0.008 Identities = 25/84 (29%), Positives = 29/84 (34%), Gaps = 15/84 (17%) Query: 91 CRNGGTCVLGSF---CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC----------- 136 C+NGG C C CP+ +TG YC+ E A G R C Sbjct: 1068 CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGN 1127 Query: 137 -HLCRCIFGALHCLPLQTPDRCDP 159 H CRC G D C P Sbjct: 1128 THHCRCQAGYTGSYCEDLVDECSP 1151 Score = 35.4 bits (80), Expect = 0.039 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 87 RPRCCRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAW---TLRACHLCR 140 +P CR+GGTC +GS+ CVC A TG CE ++G T H C Sbjct: 185 KPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECA 244 Query: 141 CIFG 144 C+ G Sbjct: 245 CLPG 248 Score = 34.3 bits (77), Expect = 0.088 Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 13/66 (19%) Query: 88 PRCCRNGGTCVL---GSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH------L 138 P C+NGGTC G CVC +TG C + A HGA CH Sbjct: 303 PNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA----TCHDRVASFY 358 Query: 139 CRCIFG 144 C C G Sbjct: 359 CECPHG 364 Score = 33.5 bits (75), Expect = 0.15 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 9/76 (11%) Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCI----F 143 C + G C+ + F C CP FTG C++D ++GA L + C+ + Sbjct: 499 CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY 558 Query: 144 GALHCLPLQTPDRCDP 159 HC D CDP Sbjct: 559 TGTHC--EVDIDECDP 572 Score = 33.1 bits (74), Expect = 0.20 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 7/65 (10%) Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRACHLCRCIFG- 144 C +GGTC GS+ C CP +TG C++ + ++G W + C C G Sbjct: 1030 CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1089 Query: 145 -ALHC 148 L+C Sbjct: 1090 TGLYC 1094 Score = 32.0 bits (71), Expect = 0.44 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 5/56 (8%) Query: 91 CRNGGTCVLGSF----CVCPAHFTGRYCEH-DQRRSECGALEHGAWTLRACHLCRC 141 CRNGGTC L + C CP ++G+ C+ D S A A ++C C Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166 Score = 32.0 bits (71), Expect = 0.44 Identities = 15/30 (50%), Positives = 17/30 (56%), Gaps = 3/30 (10%) Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHD 117 C N GTCV +G + C CP F G CE D Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267 Score = 30.4 bits (67), Expect = 1.3 Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 3/28 (10%) Query: 91 CRNGGTCVLG---SFCVCPAHFTGRYCE 115 C NGGTC+ G C+C FTG C+ Sbjct: 1357 CLNGGTCISGPRSPTCLCLGPFTGPECQ 1384 Score = 30.0 bits (66), Expect = 1.7 Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 12/75 (16%) Query: 91 CRNGGTCVLG-----SFCVCPAHFTGRYCEHDQRRSECGA--LEHGAWTLRACHLCRCIF 143 C G C + C CP+ +TG C D GA EH + C Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFEC-- 438 Query: 144 GALHCLPLQTPDRCD 158 CL T RC+ Sbjct: 439 ---QCLQGYTGPRCE 450 Score = 29.6 bits (65), Expect = 2.2 Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 4/34 (11%) Query: 88 PRCCRNGGTCV----LGSFCVCPAHFTGRYCEHD 117 P C+NGGTC + C C FTG+ CE + Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEEN 257 Score = 28.1 bits (61), Expect = 6.3 Identities = 14/43 (32%), Positives = 17/43 (39%), Gaps = 3/43 (6%) Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGA 130 C NGGTC + G C CP + C + HGA Sbjct: 687 CHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729 Score = 27.7 bits (60), Expect = 8.2 Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 3/45 (6%) Query: 74 LPYSRAFGEGASARPRCCRNGGTCVLGS---FCVCPAHFTGRYCE 115 LP A G S C NGG C + CVC F G C+ Sbjct: 14 LPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ 58 Score = 27.7 bits (60), Expect = 8.2 Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 3/30 (10%) Query: 91 CRNGGTCVL---GSFCVCPAHFTGRYCEHD 117 CR+G +C G C C A ++GR CE D Sbjct: 878 CRHGASCQNTHGGYRCHCQAGYSGRNCETD 907 >gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] Length = 810 Score = 47.8 bits (112), Expect = 8e-06 Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 14/74 (18%) Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137 G G R C CR GGTCV + CVCP+ FTG +CE D G +E CH Sbjct: 510 GNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIE--------CH 561 Query: 138 ---LCRCIFGALHC 148 C + G HC Sbjct: 562 NHSRCVNLPGWYHC 575 Score = 28.9 bits (63), Expect = 3.7 Identities = 11/25 (44%), Positives = 15/25 (60%), Gaps = 1/25 (4%) Query: 131 WTLRACHLCRCIFGALHCLPLQTPD 155 WT +C CRC+ G + C PL P+ Sbjct: 709 WT-HSCQQCRCLEGEVDCWPLTCPN 732 >gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] Length = 839 Score = 43.9 bits (102), Expect = 1e-04 Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117 G G + + C CRNGG C+ + C CP FTG CE D Sbjct: 539 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 578 Score = 32.0 bits (71), Expect = 0.44 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140 C+NG C C +C E D R S ++G W ++ C CR Sbjct: 688 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 746 Query: 141 CIFGALHCLPLQTPD 155 C+ G + C PL PD Sbjct: 747 CLQGEVDCWPLPCPD 761 >gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] Length = 815 Score = 43.9 bits (102), Expect = 1e-04 Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117 G G + + C CRNGG C+ + C CP FTG CE D Sbjct: 515 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 554 Score = 32.0 bits (71), Expect = 0.44 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140 C+NG C C +C E D R S ++G W ++ C CR Sbjct: 664 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 722 Query: 141 CIFGALHCLPLQTPD 155 C+ G + C PL PD Sbjct: 723 CLQGEVDCWPLPCPD 737 >gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 43.9 bits (102), Expect = 1e-04 Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117 G G + + C CRNGG C+ + C CP FTG CE D Sbjct: 516 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 555 Score = 32.0 bits (71), Expect = 0.44 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140 C+NG C C +C E D R S ++G W ++ C CR Sbjct: 665 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 723 Query: 141 CIFGALHCLPLQTPD 155 C+ G + C PL PD Sbjct: 724 CLQGEVDCWPLPCPD 738 >gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] Length = 866 Score = 43.9 bits (102), Expect = 1e-04 Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117 G G + + C CRNGG C+ + C CP FTG CE D Sbjct: 566 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 605 Score = 32.0 bits (71), Expect = 0.44 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140 C+NG C C +C E D R S ++G W ++ C CR Sbjct: 715 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 773 Query: 141 CIFGALHCLPLQTPD 155 C+ G + C PL PD Sbjct: 774 CLQGEVDCWPLPCPD 788 >gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 43.9 bits (102), Expect = 1e-04 Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117 G G + + C CRNGG C+ + C CP FTG CE D Sbjct: 516 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 555 Score = 32.0 bits (71), Expect = 0.44 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140 C+NG C C +C E D R S ++G W ++ C CR Sbjct: 665 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 723 Query: 141 CIFGALHCLPLQTPD 155 C+ G + C PL PD Sbjct: 724 CLQGEVDCWPLPCPD 738 >gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] Length = 1541 Score = 42.7 bits (99), Expect = 2e-04 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 4/92 (4%) Query: 79 AFGEGASARPRCCRNGGTCVLG-SFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137 +FG S CRNGGTC+LG C CP +TG C G + + + Sbjct: 515 SFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG 574 Query: 138 LCRCIFGALHCLPLQTPDRCD---PKDFLASH 166 C + GA C P + C+ PK + H Sbjct: 575 TCDSVTGACRCPPGVSGTNCEDGCPKGYYGKH 606 Score = 38.1 bits (87), Expect = 0.006 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 4/55 (7%) Query: 91 CRNGGTCVLGSF--CVCPAHFTGRYCEH--DQRRSECGALEHGAWTLRACHLCRC 141 C +GG CV GS C CP F G C++ D+ R+ G +H +LC C Sbjct: 133 CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCEC 187 Score = 37.7 bits (86), Expect = 0.008 Identities = 33/91 (36%), Positives = 38/91 (41%), Gaps = 14/91 (15%) Query: 71 EEPLPYSRAFGEGASARPRCCRNGGTC-VLGSFCVCPAHFTGRYCEHDQRRSECGALEHG 129 E P +R FG G CRNGG C C C +TGR+CE C +G Sbjct: 1289 ERGCPQNR-FGVGCE-HTCSCRNGGLCHASNGSCSCGLGWTGRHCE-----LACPPGRYG 1341 Query: 130 AWTLRACHL-CRCIFGALHCLPLQTPDRCDP 159 A ACHL C C + C P RC P Sbjct: 1342 A----ACHLECSCHNNST-CEPATGTCRCGP 1367 Score = 35.8 bits (81), Expect = 0.030 Identities = 26/109 (23%), Positives = 39/109 (35%), Gaps = 2/109 (1%) Query: 80 FGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLC 139 FG G R +C + C CPA + G +CEH G A A C Sbjct: 909 FGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC 968 Query: 140 RCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLH 188 + G+ C + RC + +H +G + A + C +H Sbjct: 969 DAVNGSCLCPAGRRGPRC--AETCPAHTYGHNCSQACACFNGASCDPVH 1015 Score = 35.0 bits (79), Expect = 0.051 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 13/80 (16%) Query: 83 GASARPRC-CRNGGTC-VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH-LC 139 GA + C C++G C + C+CPA F G +CE R E G+ G CH C Sbjct: 1384 GAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCE---RGCEPGSFGEG------CHQRC 1434 Query: 140 RCIFGALHCLPLQTPDRCDP 159 C GA C P+ C P Sbjct: 1435 DCDGGA-PCDPVTGLCLCPP 1453 Score = 34.3 bits (77), Expect = 0.088 Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 4/96 (4%) Query: 65 AEGWGPEEPLPYSRAFGEGASARPRC-CRNGGTC-VLGSFCVCPAHFTGRYCEHD-QRRS 121 A GW L A G + R C C+NGGTC + C CP + G CE + R Sbjct: 1021 APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRD 1080 Query: 122 ECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRC 157 H L LC G C T D+C Sbjct: 1081 VRAGCRHSGGCLNG-GLCDPHTGRCLCPAGWTGDKC 1115 Score = 32.3 bits (72), Expect = 0.33 Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 7/75 (9%) Query: 91 CRNGGTCVLGSFC-------VCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIF 143 CR+ G C+ G C +CPA +TG C+ R G + C + Sbjct: 1085 CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVT 1144 Query: 144 GALHCLPLQTPDRCD 158 GA C P T C+ Sbjct: 1145 GACRCPPGFTGSGCE 1159 Score = 30.8 bits (68), Expect = 0.97 Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 22/100 (22%) Query: 83 GASARPRCCRNGGTC--VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTL------R 134 G + C G C V G C CP TG CE D G W L Sbjct: 737 GVNCSSSCSCGGAPCHGVTGQ-CRCPPGRTGEDCEAD--------CPEGRWGLGCQEICP 787 Query: 135 AC-HLCRC--IFGALHCLPLQTPDRCDPKDFLASHAHGPS 171 AC H RC GA CLP RC +D + +GPS Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRC--QDVCPAGWYGPS 825 Score = 30.4 bits (67), Expect = 1.3 Identities = 21/68 (30%), Positives = 26/68 (38%), Gaps = 10/68 (14%) Query: 83 GASARPRC-CRNGGTCVLGS-FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCR 140 G S + RC C N G C + C C +TG C+ A + G W H C Sbjct: 823 GPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQR--------ACDTGHWGPDCSHPCN 874 Query: 141 CIFGALHC 148 C G C Sbjct: 875 CSAGHGSC 882 Score = 30.4 bits (67), Expect = 1.3 Identities = 33/97 (34%), Positives = 37/97 (38%), Gaps = 17/97 (17%) Query: 83 GASARPRC-CRNGGTCVLGS-FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH-LC 139 GA+ C C N TC + C C F G+ CEH C HGA C LC Sbjct: 1341 GAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEH-----PCPPGFHGA----GCQGLC 1391 Query: 140 RCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAP 176 C GA C P+ C P F H H G P Sbjct: 1392 WCQHGA-PCDPISGRCLC-PAGF---HGHFCERGCEP 1423 Score = 30.4 bits (67), Expect = 1.3 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 11/80 (13%) Query: 79 AFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHL 138 +FGEG R C + C+CP +G C D RR + G +C L Sbjct: 1425 SFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP---------SCTL 1475 Query: 139 -CRCIFGALHCLPLQTPDRC 157 C C GA C P+ C Sbjct: 1476 HCDCGGGA-DCDPVSGQCHC 1494 Score = 29.3 bits (64), Expect = 2.8 Identities = 21/70 (30%), Positives = 26/70 (37%), Gaps = 10/70 (14%) Query: 91 CRNGGTCVLGS-FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149 C NGG+C + C CP F G C G + H+C C GA C Sbjct: 1221 CLNGGSCDAATGACRCPTGFLGTDCNL--------TCPQGRFGPNCTHVCGCGQGAA-CD 1271 Query: 150 PLQTPDRCDP 159 P+ C P Sbjct: 1272 PVTGTCLCPP 1281 Score = 28.1 bits (61), Expect = 6.3 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 14/76 (18%) Query: 80 FGEGASARPRCCRNGGTC-VLGSFCVCPAHFTGRYCEHD----------QRRSECGALEH 128 +G S C G+C + C+C A + G CE ++R +C +H Sbjct: 865 WGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQC---QH 921 Query: 129 GAWTLRACHLCRCIFG 144 GA C C G Sbjct: 922 GAACDHVSGACTCPAG 937 >gi|110347437 latent transforming growth factor beta binding protein 4 isoform c [Homo sapiens] Length = 1557 Score = 42.4 bits (98), Expect = 3e-04 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 11/67 (16%) Query: 49 SPLNWTSSHFGEVTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAH 108 +P N TS G G+A G GP G A P C NGG CV C+CP Sbjct: 59 APRNATSVDSGAPGGAAPG-GP----------GFRAFLCPLICHNGGVCVKPDRCLCPPD 107 Query: 109 FTGRYCE 115 F G++C+ Sbjct: 108 FAGKFCQ 114 Score = 30.4 bits (67), Expect = 1.3 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 10/50 (20%) Query: 78 RAFGEGASARP--RCCRNGGTC-------VLGSF-CVCPAHFTGRYCEHD 117 +A GAS + C ++ G C + GSF CVCPA F G CE D Sbjct: 594 QAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 643 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 41.6 bits (96), Expect = 5e-04 Identities = 40/127 (31%), Positives = 49/127 (38%), Gaps = 26/127 (20%) Query: 85 SARPRCCRNGGTC----VLGSFCVCPAHFTGRYCEHDQ----RRSECGALEHGAWTLR-- 134 + R R C+NGG C CVCPA FTG CEH Q CG A + Sbjct: 3847 TCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGP---DATCVNRP 3903 Query: 135 --ACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLHRLLR 192 + CRC G ++ RC+ + + PS GA S L L H LR Sbjct: 3904 DGRGYTCRCHLG-------RSGLRCEEGVTVTT----PSLSGAGSYLALPALTNTHHELR 3952 Query: 193 PDAPAHP 199 D P Sbjct: 3953 LDVEFKP 3959 Score = 37.0 bits (84), Expect = 0.014 Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 27/124 (21%) Query: 49 SPLNWTSSHFGEVTGSAEGWGPEEPLPYS----RAFGEGASARP---RCCRNGGTCV-LG 100 SP S+HF G G L YS + G+ + P + C++G TC+ G Sbjct: 4064 SPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAG 4123 Query: 101 SF---CVCPAHFTGRYCEHD----QRRSECGALEHGAWTLRACHLCRCIFGALHCLPLQT 153 + C+C F G CEH+ Q R C HG C RC+ CLP + Sbjct: 4124 EYEFQCLCRDGFKGDLCEHEENPCQLREPC---LHGG----TCQGTRCL-----CLPGFS 4171 Query: 154 PDRC 157 RC Sbjct: 4172 GPRC 4175 >gi|21704279 jagged 2 isoform b precursor [Homo sapiens] Length = 1200 Score = 41.6 bits (96), Expect = 5e-04 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 16/64 (25%) Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH---LCRCIFG 144 C++GGTC V G CVCP F GR+CE + R EC + CH LC + Sbjct: 431 CQHGGTCKDLVNGYQCVCPRGFGGRHCELE--RDECAS--------SPCHSGGLCEDLAD 480 Query: 145 ALHC 148 HC Sbjct: 481 GFHC 484 Score = 34.3 bits (77), Expect = 0.088 Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGA--WTLRACHLCRC--IF 143 C +GG C G C CP F+G CE D E +GA + L + C C F Sbjct: 469 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 528 Query: 144 GALHC 148 G +C Sbjct: 529 GGKNC 533 Score = 33.9 bits (76), Expect = 0.11 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 5/51 (9%) Query: 79 AFGEGASARPRCCRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGAL 126 A + +S P C NGGTCV C+C + GR C H+ ++C L Sbjct: 710 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN--TNDCNPL 758 Score = 32.3 bits (72), Expect = 0.33 Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 8/51 (15%) Query: 91 CRNGGTCVLGS----FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137 C NGGTC+ C CP ++GR CE + +G +CH Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG----SCH 363 Score = 31.6 bits (70), Expect = 0.57 Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 3/28 (10%) Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCE 115 CRNGGTC+ + +F C CP+ + G C+ Sbjct: 607 CRNGGTCIDEVDAFRCFCPSGWEGELCD 634 Score = 30.4 bits (67), Expect = 1.3 Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 8/66 (12%) Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEH-----DQRRSECGALEHGAWTLRACHLCRCI 142 C G TCV G C CP G C+ S HG+ + C+ CRC+ Sbjct: 798 CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCL 857 Query: 143 FGALHC 148 G C Sbjct: 858 DGRRDC 863 Score = 27.7 bits (60), Expect = 8.2 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 4/41 (9%) Query: 81 GEGASARPRCCRNGGTCVL---GSF-CVCPAHFTGRYCEHD 117 G +A C G CV G+F C+C + FTG YC + Sbjct: 558 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 598 >gi|21704277 jagged 2 isoform a precursor [Homo sapiens] Length = 1238 Score = 41.6 bits (96), Expect = 5e-04 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 16/64 (25%) Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH---LCRCIFG 144 C++GGTC V G CVCP F GR+CE + R EC + CH LC + Sbjct: 469 CQHGGTCKDLVNGYQCVCPRGFGGRHCELE--RDECAS--------SPCHSGGLCEDLAD 518 Query: 145 ALHC 148 HC Sbjct: 519 GFHC 522 Score = 34.3 bits (77), Expect = 0.088 Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGA--WTLRACHLCRC--IF 143 C +GG C G C CP F+G CE D E +GA + L + C C F Sbjct: 507 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 566 Query: 144 GALHC 148 G +C Sbjct: 567 GGKNC 571 Score = 33.9 bits (76), Expect = 0.11 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 5/51 (9%) Query: 79 AFGEGASARPRCCRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGAL 126 A + +S P C NGGTCV C+C + GR C H+ ++C L Sbjct: 748 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN--TNDCNPL 796 Score = 32.3 bits (72), Expect = 0.33 Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 8/51 (15%) Query: 91 CRNGGTCVLGS----FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137 C NGGTC+ C CP ++GR CE + +G +CH Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG----SCH 363 Score = 31.6 bits (70), Expect = 0.57 Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 3/28 (10%) Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCE 115 CRNGGTC+ + +F C CP+ + G C+ Sbjct: 645 CRNGGTCIDEVDAFRCFCPSGWEGELCD 672 Score = 30.4 bits (67), Expect = 1.3 Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 8/66 (12%) Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEH-----DQRRSECGALEHGAWTLRACHLCRCI 142 C G TCV G C CP G C+ S HG+ + C+ CRC+ Sbjct: 836 CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCL 895 Query: 143 FGALHC 148 G C Sbjct: 896 DGRRDC 901 Score = 27.7 bits (60), Expect = 8.2 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 4/41 (9%) Query: 81 GEGASARPRCCRNGGTCVL---GSF-CVCPAHFTGRYCEHD 117 G +A C G CV G+F C+C + FTG YC + Sbjct: 596 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 636 >gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [Homo sapiens] Length = 1138 Score = 41.2 bits (95), Expect = 7e-04 Identities = 19/38 (50%), Positives = 24/38 (63%), Gaps = 1/38 (2%) Query: 83 GASARPRC-CRNGGTCVLGSFCVCPAHFTGRYCEHDQR 119 GA R +C C+NGGTC S CVCP+ + G +CE R Sbjct: 312 GADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDR 349 Score = 31.2 bits (69), Expect = 0.74 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 80 FGEGASARPRCCRNGGTCV-LGSFCVCPAHFTGRYCEHDQRRSECG 124 +G G + C +GG C CVCP FTG CE R G Sbjct: 220 WGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFG 265 >gi|110347412 latent transforming growth factor beta binding protein 4 isoform b [Homo sapiens] Length = 1587 Score = 41.2 bits (95), Expect = 7e-04 Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 9/80 (11%) Query: 45 KHRQSPLNWTSSHFGEVTGSAEGWGPEEP---------LPYSRAFGEGASARPRCCRNGG 95 + RQ LNW E + P P P G+ P C NGG Sbjct: 65 RKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGG 124 Query: 96 TCVLGSFCVCPAHFTGRYCE 115 CV C+CP F G++C+ Sbjct: 125 VCVKPDRCLCPPDFAGKFCQ 144 Score = 30.4 bits (67), Expect = 1.3 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 10/50 (20%) Query: 78 RAFGEGASARP--RCCRNGGTC-------VLGSF-CVCPAHFTGRYCEHD 117 +A GAS + C ++ G C + GSF CVCPA F G CE D Sbjct: 624 QAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 673 >gi|110347431 latent transforming growth factor beta binding protein 4 isoform a [Homo sapiens] Length = 1624 Score = 41.2 bits (95), Expect = 7e-04 Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 9/80 (11%) Query: 45 KHRQSPLNWTSSHFGEVTGSAEGWGPEEP---------LPYSRAFGEGASARPRCCRNGG 95 + RQ LNW E + P P P G+ P C NGG Sbjct: 102 RKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGG 161 Query: 96 TCVLGSFCVCPAHFTGRYCE 115 CV C+CP F G++C+ Sbjct: 162 VCVKPDRCLCPPDFAGKFCQ 181 Score = 30.4 bits (67), Expect = 1.3 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 10/50 (20%) Query: 78 RAFGEGASARP--RCCRNGGTC-------VLGSF-CVCPAHFTGRYCEHD 117 +A GAS + C ++ G C + GSF CVCPA F G CE D Sbjct: 661 QAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 710 >gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] Length = 3144 Score = 40.8 bits (94), Expect = 0.001 Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 8/35 (22%) Query: 91 CRNGGTC--------VLGSFCVCPAHFTGRYCEHD 117 C NGGTC ++ C CP HFTGR+CE D Sbjct: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142 Score = 33.1 bits (74), Expect = 0.20 Identities = 12/28 (42%), Positives = 18/28 (64%), Gaps = 3/28 (10%) Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115 CRN GTC+ + FC CP ++G+ C+ Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ 2371 Score = 32.7 bits (73), Expect = 0.26 Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 7/43 (16%) Query: 91 CRNGGTC----VLGSF-CVCPAHFTGRYCEHDQRRSECGALEH 128 C NGG C + G F C+CP +TG++C QR + C L + Sbjct: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFCH--QRYNLCDLLHN 858 Score = 31.2 bits (69), Expect = 0.74 Identities = 13/28 (46%), Positives = 15/28 (53%), Gaps = 3/28 (10%) Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCE 115 C N G C G C+CP +TG YCE Sbjct: 1088 CMNEGFCQKSAHGFTCICPRGYTGAYCE 1115 Score = 31.2 bits (69), Expect = 0.74 Identities = 14/31 (45%), Positives = 15/31 (48%), Gaps = 3/31 (9%) Query: 88 PRCCRNGGTCVL---GSFCVCPAHFTGRYCE 115 P C G TC+ G C CP TG YCE Sbjct: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689 Score = 30.4 bits (67), Expect = 1.3 Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 24/71 (33%) Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYC---------EHD-----QRRSECGALEHGAWTL 133 C NGGTC+ +C C + G +C EHD R + C +L HG Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHG---- 2674 Query: 134 RACHLCRCIFG 144 + C C G Sbjct: 2675 ---YTCFCPLG 2682 Score = 30.0 bits (66), Expect = 1.7 Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 4/44 (9%) Query: 91 CRNGGTCVLGSF----CVCPAHFTGRYCEHDQRRSECGALEHGA 130 C NGG CV G C C F+G++CE + HGA Sbjct: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGA 1174 Score = 29.3 bits (64), Expect = 2.8 Identities = 12/31 (38%), Positives = 15/31 (48%), Gaps = 4/31 (12%) Query: 91 CRNGGTCVL----GSFCVCPAHFTGRYCEHD 117 CRN TC+ C+C F G+ CE D Sbjct: 860 CRNNSTCLALVDANQHCICREEFEGKNCEID 890 Score = 29.3 bits (64), Expect = 2.8 Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 3/30 (10%) Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCEHD 117 C+N GTCV + FC C + G +CE D Sbjct: 937 CKNNGTCVDLTNRFFCNCEPEYHGPFCELD 966 Score = 28.9 bits (63), Expect = 3.7 Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 8/70 (11%) Query: 53 WTSSHFGEVTGSA----EGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGS----FCV 104 W + H G+ E E P YS + AS C NG TCV S C+ Sbjct: 2338 WCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCL 2397 Query: 105 CPAHFTGRYC 114 CP +G C Sbjct: 2398 CPYGRSGPLC 2407 Score = 27.7 bits (60), Expect = 8.2 Identities = 21/72 (29%), Positives = 27/72 (37%), Gaps = 21/72 (29%) Query: 91 CRNGGTC-----------------VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTL 133 C+NG TC V G C+C + G CE D A EH + T Sbjct: 690 CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNS-TC 748 Query: 134 RACHL---CRCI 142 + HL C C+ Sbjct: 749 KDLHLSYQCVCL 760 >gi|88702793 slit-like 2 [Homo sapiens] Length = 673 Score = 40.8 bits (94), Expect = 0.001 Identities = 18/32 (56%), Positives = 20/32 (62%), Gaps = 4/32 (12%) Query: 88 PRCCRNGGTCVLGS----FCVCPAHFTGRYCE 115 P C NGGTC LG+ C+CP FTG YCE Sbjct: 411 PSTCLNGGTCHLGTRHHLACLCPEGFTGLYCE 442 >gi|134244285 Notch homolog 3 [Homo sapiens] Length = 2321 Score = 40.4 bits (93), Expect = 0.001 Identities = 35/106 (33%), Positives = 40/106 (37%), Gaps = 15/106 (14%) Query: 81 GEGASARPRCCRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC- 136 G + PRC NG TCV +G F C CP +TG CE D GA H A T R C Sbjct: 1167 GPPLDSGPRCLHNG-TCVDLVGGFRCTCPPGYTGLRCEADINECRSGAC-HAAHT-RDCL 1223 Query: 137 --------HLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGG 174 LC F C + +P P P GG Sbjct: 1224 QDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGG 1269 Score = 38.1 bits (87), Expect = 0.006 Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 15/106 (14%) Query: 74 LPYSRAFGEGASARPRCCRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGALEHGA 130 LP A + + C+ GG CV +CVCP TG +CE + +HG Sbjct: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGG 1097 Query: 131 WTLRACHLCRCIFGA--LHCLPLQTPDRC-DPKDFLASH--AHGPS 171 CR G CLP D C D D AS HG S Sbjct: 1098 -------TCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGS 1136 Score = 37.0 bits (84), Expect = 0.014 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 3/33 (9%) Query: 88 PRCCRNGGTCVLG--SF-CVCPAHFTGRYCEHD 117 P C NGGTCV G SF C+C +TG +C+H+ Sbjct: 930 PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962 Score = 37.0 bits (84), Expect = 0.014 Identities = 16/42 (38%), Positives = 26/42 (61%), Gaps = 3/42 (7%) Query: 75 PYSRAFGEGASARPRCCRNGGTCV-LGSFCVCPAHFTGRYCE 115 P + + S +P C+NGG CV G++C+CP ++GR C+ Sbjct: 995 PQCQTLVDWCSRQP--CQNGGRCVQTGAYCLCPPGWSGRLCD 1034 Score = 36.6 bits (83), Expect = 0.018 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 11/63 (17%) Query: 91 CRNGGTCVLGSF---CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC------HLCRC 141 C NGGTCV G C CP +TG++C D EC + C H C C Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV--DECQLQPNACHNGGTCFNTLGGHSCVC 302 Query: 142 IFG 144 + G Sbjct: 303 VNG 305 Score = 36.6 bits (83), Expect = 0.018 Identities = 17/30 (56%), Positives = 20/30 (66%), Gaps = 3/30 (10%) Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHD 117 CRN TC+ +G F C+C A FTG YCE D Sbjct: 440 CRNQATCLDRIGQFTCICMAGFTGTYCEVD 469 Score = 35.8 bits (81), Expect = 0.030 Identities = 17/29 (58%), Positives = 21/29 (72%), Gaps = 3/29 (10%) Query: 91 CRNGGTCVL--GSF-CVCPAHFTGRYCEH 116 CR+GGTC+ GSF C CPA +TG CE+ Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196 Score = 35.4 bits (80), Expect = 0.039 Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 5/74 (6%) Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRA--CHLCRCIFGA 145 C NGG C V G C CP+ F+G C+ D +GA + + CRC G Sbjct: 478 CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGF 537 Query: 146 LHCLPLQTPDRCDP 159 L + D C P Sbjct: 538 EGTLCDRNVDDCSP 551 Score = 35.0 bits (79), Expect = 0.051 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 13/67 (19%) Query: 87 RPRCCRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH------ 137 +P C NGGTC + G CVC +TG C + HGA CH Sbjct: 281 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGA----TCHDRVASF 336 Query: 138 LCRCIFG 144 C C G Sbjct: 337 YCACPMG 343 Score = 32.3 bits (72), Expect = 0.33 Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 7/37 (18%) Query: 86 ARPRC----CRNGGTCV---LGSFCVCPAHFTGRYCE 115 AR C CR GGTC +G C CP GR CE Sbjct: 734 ARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCE 770 Score = 29.3 bits (64), Expect = 2.8 Identities = 20/66 (30%), Positives = 24/66 (36%), Gaps = 5/66 (7%) Query: 91 CRNGGTCVLGS----FCVCPAHFTGRYCEHDQRRSECG-ALEHGAWTLRACHLCRCIFGA 145 C +G C +G C CP + GR C D G HG L RC A Sbjct: 128 CAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPA 187 Query: 146 LHCLPL 151 + PL Sbjct: 188 GYTGPL 193 Score = 29.3 bits (64), Expect = 2.8 Identities = 15/32 (46%), Positives = 16/32 (50%), Gaps = 4/32 (12%) Query: 88 PRCCRNGGTC----VLGSFCVCPAHFTGRYCE 115 P CRNGGTC L C C F G+ CE Sbjct: 203 PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE 234 Score = 28.9 bits (63), Expect = 3.7 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 17/80 (21%) Query: 86 ARPRCCRN----------GGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWT 132 A PRC R+ GTC + SF C CP + G +CE D + +G Sbjct: 880 AGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC 939 Query: 133 LRACH----LCRCIFGALHC 148 + + LCR + HC Sbjct: 940 VDGVNSFSCLCRPGYTGAHC 959 Score = 27.7 bits (60), Expect = 8.2 Identities = 15/43 (34%), Positives = 18/43 (41%), Gaps = 9/43 (20%) Query: 101 SFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC-HLCRCI 142 + C CP FTG C+ D GA C HL RC+ Sbjct: 375 AICTCPPGFTGGACDQDVDECSIGA--------NPCEHLGRCV 409 Score = 27.7 bits (60), Expect = 8.2 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 5/55 (9%) Query: 95 GTCVLG--SF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC--HLCRCIFG 144 G CV G SF C C +TG CE HG L +LCRC G Sbjct: 557 GRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG 611 >gi|189491645 fibulin 7 isoform 1 [Homo sapiens] Length = 439 Score = 40.0 bits (92), Expect = 0.002 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 8/84 (9%) Query: 68 WGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSF---CVCPAHFTGRYCEHDQRRSECG 124 W E+P + R E S++P C+NGGTCV G C+CP TG C+H + + Sbjct: 127 WTGEQP--HCRGISE-CSSQP--CQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPE 181 Query: 125 ALEHGAWTLRACHLCRCIFGALHC 148 G C + A HC Sbjct: 182 GSVAGDSAFSRAPRCAQVERAQHC 205 >gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] Length = 4981 Score = 40.0 bits (92), Expect = 0.002 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 10/65 (15%) Query: 88 PRCCRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFG 144 P C +GGTC ++G F C CP FTGR CE D ++GA +C+ G Sbjct: 3868 PSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGA-------ICQNFPG 3920 Query: 145 ALHCL 149 + +C+ Sbjct: 3921 SFNCV 3925 Score = 38.1 bits (87), Expect = 0.006 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 91 CRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRA--CHLCRCIFGA 145 C+NG C GSF CVC +TG+ CE EC +G + C C FG Sbjct: 3909 CKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGV 3968 Query: 146 L--HC 148 HC Sbjct: 3969 FGKHC 3973 Score = 30.8 bits (68), Expect = 0.97 Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 4/29 (13%) Query: 91 CRNGGTCVLGSF----CVCPAHFTGRYCE 115 C+NGG+C G C CP TGR CE Sbjct: 4435 CQNGGSCEPGLHSGFTCSCPDSHTGRTCE 4463 Score = 30.0 bits (66), Expect = 1.7 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 4/37 (10%) Query: 82 EGASARPRCCRNGGTCV---LGSFCVCPAHFTGRYCE 115 EGA R C ++GGTC+ C C TG+YCE Sbjct: 4163 EGACTRSPC-QHGGTCMDYWSWQQCHCKEGLTGKYCE 4198 Score = 28.5 bits (62), Expect = 4.8 Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 3/28 (10%) Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115 C NGG+C G +C CP G++CE Sbjct: 3947 CFNGGSCQSGVDSYYCHCPFGVFGKHCE 3974 >gi|122937283 6720455I24Rik homolog [Homo sapiens] Length = 1413 Score = 40.0 bits (92), Expect = 0.002 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 82 EGASARPRCCRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRAC 136 E R CRNGG+C + G++ C CPA F G +CE + + +HG + Sbjct: 791 ERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGA 850 Query: 137 HLCRC--IFGALHCLPLQTP 154 +LC C F HC + P Sbjct: 851 YLCVCPESFFGYHCETVSDP 870 Score = 38.1 bits (87), Expect = 0.006 Identities = 35/114 (30%), Positives = 42/114 (36%), Gaps = 10/114 (8%) Query: 91 CRNGGTCVLG--SF-CVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRACHLCRCIFGA 145 C+NGGTC G SF C CPA F G CE Q + +HG +C C G Sbjct: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379 Query: 146 LHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLHRLLRPDAPAHP 199 D C P L + G L CA + LR + HP Sbjct: 380 TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCL-----CAEPFKGLRCETGDHP 428 Score = 37.7 bits (86), Expect = 0.008 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 17/81 (20%) Query: 91 CRNGGTCVLGS--FCVCPAHFTGRYCEHDQRRSECG----------ALEHGAWTLRACHL 138 CRNGG C+ + C CP F G CE + C +EHG L CH Sbjct: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHT 533 Query: 139 CRCIFGALHCLPLQTPDRCDP 159 A H LP +P DP Sbjct: 534 DH---NASHSLP--SPCDSDP 549 Score = 37.4 bits (85), Expect = 0.010 Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 3/28 (10%) Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115 CRNGGTC C CP FTGR+CE Sbjct: 589 CRNGGTCKEAGGEYHCSCPYRFTGRHCE 616 Score = 36.2 bits (82), Expect = 0.023 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 7/69 (10%) Query: 87 RPRCCRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRACHLCRC 141 R + C +GG+C V G C+C + G +CE ++ +G L ++CRC Sbjct: 758 RSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRC 817 Query: 142 IFG--ALHC 148 G +HC Sbjct: 818 PAGFVGVHC 826 Score = 35.0 bits (79), Expect = 0.051 Identities = 15/28 (53%), Positives = 19/28 (67%), Gaps = 3/28 (10%) Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCE 115 C NGGTC +G + C CP F+GR+CE Sbjct: 628 CHNGGTCFHYIGKYKCDCPPGFSGRHCE 655 Score = 34.7 bits (78), Expect = 0.067 Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 21/88 (23%) Query: 89 RCCRNGGTC----VLGS---FCVCPAHFTGRYCEHDQRRSEC--------GALEHGAWTL 133 R C NGG C V G+ C C + FTGR C D +EC G HG + Sbjct: 276 RPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDV--NECASQPCQNGGTCTHGINSF 333 Query: 134 RACHLCRCIFGALHCLPLQTPDRCDPKD 161 R C FG C Q+P CD K+ Sbjct: 334 RC--QCPAGFGGPTCETAQSP--CDTKE 357 Score = 33.9 bits (76), Expect = 0.11 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 4/57 (7%) Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFG 144 C NGGTCV G C CP F G C ++ +C G LC+C G Sbjct: 438 CHNGGTCVDADQGYVCECPEGFMGLDC-RERVPDDCECRNGGRCLGANTTLCQCPLG 493 Score = 32.3 bits (72), Expect = 0.33 Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 3/28 (10%) Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115 C+NGGTCV G+ C C F GR CE Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE 1343 Score = 30.0 bits (66), Expect = 1.7 Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 6/40 (15%) Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGALE 127 C NGGTC FC C A + GR C Q +CG E Sbjct: 666 CVNGGTCEDRDTDFFCHCQAGYMGRRC---QAEVDCGPPE 702 Score = 29.3 bits (64), Expect = 2.8 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 12/82 (14%) Query: 88 PRCCRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC------HL 138 P C NGG+CV +G++ C+C F G CE L C ++ Sbjct: 393 PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYV 452 Query: 139 CRCI--FGALHCLPLQTPDRCD 158 C C F L C + PD C+ Sbjct: 453 CECPEGFMGLDCRE-RVPDDCE 473 Score = 28.5 bits (62), Expect = 4.8 Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 9/75 (12%) Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCEHDQ-RRSECGALEHGAWTLRAC--HLCRC--I 142 C NGG+C C CP F G++CE + G +G A + C C Sbjct: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609 Query: 143 FGALHCLPLQTPDRC 157 F HC + PD C Sbjct: 610 FTGRHC-EIGKPDSC 623 >gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] Length = 1590 Score = 39.7 bits (91), Expect = 0.002 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 6/69 (8%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLP 150 C++GGTC+ G+ C CP F G CE C E+G L +C+C G P Sbjct: 1366 CQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHC---ENGGQCLTP-DICQCKPGWYG--P 1419 Query: 151 LQTPDRCDP 159 + CDP Sbjct: 1420 TCSTALCDP 1428 Score = 35.8 bits (81), Expect = 0.030 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 6/87 (6%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLP 150 C NGG+C + C+CP F G +C++ C ++G +R ++C C G + Sbjct: 1430 CLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPC---KNGGHCMRN-NVCVCREG--YTGR 1483 Query: 151 LQTPDRCDPKDFLASHAHGPSAGGAPS 177 CDP GPS PS Sbjct: 1484 RFQKSICDPTCMNGGKCVGPSTCSCPS 1510 Score = 34.3 bits (77), Expect = 0.088 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 4/54 (7%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFG 144 C+N G C+ + C C G C+ + C +HG T A +LC C +G Sbjct: 1334 CKNHGKCIKPNICQCLPGHGGATCDEEHCNPPC---QHGG-TCLAGNLCTCPYG 1383 Score = 33.5 bits (75), Expect = 0.15 Identities = 11/25 (44%), Positives = 16/25 (64%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCE 115 C+NGG C+ S C CP+ + G C+ Sbjct: 1526 CKNGGECIAPSICHCPSSWEGVRCQ 1550 Score = 32.7 bits (73), Expect = 0.26 Identities = 12/24 (50%), Positives = 16/24 (66%) Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC 114 C NGG CV S C CP+ ++G+ C Sbjct: 1494 CMNGGKCVGPSTCSCPSGWSGKRC 1517 >gi|189491647 fibulin 7 isoform 2 [Homo sapiens] Length = 393 Score = 39.7 bits (91), Expect = 0.002 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 10/86 (11%) Query: 68 WGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSF---CVCPAHFTGRYCEHDQRR--SE 122 W E+P + R E S++P C+NGGTCV G C+CP TG C+H + +E Sbjct: 127 WTGEQP--HCRGISE-CSSQP--CQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTDVNE 181 Query: 123 CGALEHGAWTLRACHLCRCIFGALHC 148 C H C G+ C Sbjct: 182 CELYGQEGRPRLCMHACVNTPGSYRC 207 >gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] Length = 4588 Score = 39.7 bits (91), Expect = 0.002 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 14/75 (18%) Query: 81 GEGASARPRC----CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTL 133 G+ P C C+NGGTC + G+ C C + F G C+ D HGA Sbjct: 4084 GQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGA--- 4140 Query: 134 RACHLCRCIFGALHC 148 LC G+ HC Sbjct: 4141 ----LCENTHGSYHC 4151 Score = 29.3 bits (64), Expect = 2.8 Identities = 12/29 (41%), Positives = 16/29 (55%), Gaps = 4/29 (13%) Query: 91 CRNGGTC----VLGSFCVCPAHFTGRYCE 115 C+NGG C G +C C A + G +CE Sbjct: 4022 CQNGGVCNPSPAGGYYCKCSALYIGTHCE 4050 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.139 0.477 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,024,808 Number of Sequences: 37866 Number of extensions: 576124 Number of successful extensions: 2761 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 69 Number of HSP's successfully gapped in prelim test: 107 Number of HSP's that attempted gapping in prelim test: 2130 Number of HSP's gapped (non-prelim): 646 length of query: 223 length of database: 18,247,518 effective HSP length: 98 effective length of query: 125 effective length of database: 14,536,650 effective search space: 1817081250 effective search space used: 1817081250 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.