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Search of human proteins with 98986450
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]
(422 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|98986450 casein kinase 1, gamma 1 [Homo sapiens] 870 0.0
gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens] 699 0.0
gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens] 690 0.0
gi|153791733 casein kinase 1, gamma 2 [Homo sapiens] 685 0.0
gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens] 684 0.0
gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens] 675 0.0
gi|23199991 casein kinase 1 epsilon [Homo sapiens] 365 e-101
gi|4503093 casein kinase 1 epsilon [Homo sapiens] 365 e-101
gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens] 359 2e-99
gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens] 359 2e-99
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] 332 3e-91
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] 322 3e-88
gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens] 319 3e-87
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 163 2e-40
gi|116812624 tau tubulin kinase 2 [Homo sapiens] 153 3e-37
gi|4507903 vaccinia related kinase 1 [Homo sapiens] 120 3e-27
gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens] 97 2e-20
gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens] 97 2e-20
gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens] 97 2e-20
gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens] 97 2e-20
gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens] 97 2e-20
gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens] 88 1e-17
gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens] 86 8e-17
gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens] 86 8e-17
gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform... 72 1e-12
gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent ... 72 1e-12
gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo ... 72 1e-12
gi|4826948 protein kinase, X-linked [Homo sapiens] 70 4e-12
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens] 68 1e-11
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens] 68 1e-11
>gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]
Length = 422
Score = 870 bits (2248), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL 60
MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 1 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL 60
Query: 61 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL
Sbjct: 61 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
Query: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE
Sbjct: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
Query: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM
Sbjct: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
Query: 241 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE 300
FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE
Sbjct: 241 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE 300
Query: 301 KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP 360
KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP
Sbjct: 301 KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP 360
Query: 361 SQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQR 420
SQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQR
Sbjct: 361 SQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQR 420
Query: 421 HK 422
HK
Sbjct: 421 HK 422
>gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens]
Length = 415
Score = 699 bits (1804), Expect = 0.0
Identities = 344/422 (81%), Positives = 374/422 (88%), Gaps = 7/422 (1%)
Query: 1 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL 60
M++ ++KD+ + RS H +R +GSSSS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSS-GVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 61 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQLGS G+G+PQVYYFGPCGKYNAMVLEL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGS-GDGIPQVYYFGPCGKYNAMVLEL 118
Query: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
LGPSLEDLFDLCDRTF+LKTVLMIAIQL+SRMEYVHSKNLIYRDVKPENFLIGR GNK +
Sbjct: 119 LGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQ 178
Query: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM
Sbjct: 179 QVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 238
Query: 241 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE 300
FMYFLRGSLPWQGLKADTLKERYQKIGDTKR TPIE LCENFP EMATYLRYVRRLDFFE
Sbjct: 239 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFE 297
Query: 301 KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP 360
KPDY+YLR LFTDLF++KGY FDY YDW+G+ +PTPVG+V D S+ RE+H HRD+
Sbjct: 298 KPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSS-NREAHQHRDKM 356
Query: 361 SQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQR 420
Q +NQVVSSTNGELN DDPT SNAPITA EVEV++E KCCCFFKR+++KT QR
Sbjct: 357 QQS---KNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQR 413
Query: 421 HK 422
HK
Sbjct: 414 HK 415
>gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens]
Length = 423
Score = 690 bits (1780), Expect = 0.0
Identities = 343/430 (79%), Positives = 373/430 (86%), Gaps = 15/430 (3%)
Query: 1 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL 60
M++ ++KD+ + RS H +R +GSSSS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSS-GVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 61 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQLGS G+G+PQVYYFGPCGKYNAMVLEL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGS-GDGIPQVYYFGPCGKYNAMVLEL 118
Query: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
LGPSLEDLFDLCDRTF+LKTVLMIAIQL+SRMEYVHSKNLIYRDVKPENFLIGR GNK +
Sbjct: 119 LGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQ 178
Query: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM
Sbjct: 179 QVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 238
Query: 241 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE 300
FMYFLRGSLPWQGLKADTLKERYQKIGDTKR TPIE LCENFP EMATYLRYVRRLDFFE
Sbjct: 239 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFE 297
Query: 301 KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP 360
KPDY+YLR LFTDLF++KGY FDY YDW+G+ +PTPVG+V D S+ RE+H HRD+
Sbjct: 298 KPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSS-NREAHQHRDKM 356
Query: 361 SQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAK--------CCCFFKR 412
Q +NQVVSSTNGELN DDPT SNAPITA EVEV++E CCCFFKR
Sbjct: 357 QQS---KNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKR 413
Query: 413 KRKKTAQRHK 422
+++KT QRHK
Sbjct: 414 RKRKTIQRHK 423
>gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]
Length = 415
Score = 685 bits (1768), Expect = 0.0
Identities = 333/416 (80%), Positives = 364/416 (87%), Gaps = 11/416 (2%)
Query: 7 EKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYT 66
E +E +R +K RS+H R SG+SS GVLMVGPNFRVGKKIGCGNFGELRLGKNLYT
Sbjct: 11 ETEEGRRMSKAGGGRSSHGIRSSGTSS--GVLMVGPNFRVGKKIGCGNFGELRLGKNLYT 68
Query: 67 NEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLE 126
NEYVAIKLEPIKSRAPQLHLEYRFYKQL SA EG+PQVYYFGPCGKYNAMVLELLGPSLE
Sbjct: 69 NEYVAIKLEPIKSRAPQLHLEYRFYKQL-SATEGVPQVYYFGPCGKYNAMVLELLGPSLE 127
Query: 127 DLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHII 186
DLFDLCDRTFTLKTVLMIAIQL++RMEYVH+K+LIYRDVKPENFL+GR G K++H IHII
Sbjct: 128 DLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHII 187
Query: 187 DFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 246
DFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR
Sbjct: 188 DFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 247
Query: 247 GSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEY 306
GSLPWQGLKADTLKERYQKIGDTKR TPIE LCENFPEEMATYLRYVRRLDFFEKPDY+Y
Sbjct: 248 GSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDY 307
Query: 307 LRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPL 366
LR LFTDLF++ G+ FDY YDW G+P+PTP+G+VH D + R+ Q
Sbjct: 308 LRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRD--------KTQPHS 359
Query: 367 RNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK 422
+NQ ++STNGELN DDPT HSNAPITA AEVEV +E KCCCFFKR+++K+ QRHK
Sbjct: 360 KNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK 415
>gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]
Length = 447
Score = 684 bits (1765), Expect = 0.0
Identities = 345/451 (76%), Positives = 375/451 (83%), Gaps = 33/451 (7%)
Query: 1 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL 60
M++ ++KD+ + RS H +R +GSSSS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSS-GVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 61 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQLGS G+G+PQVYYFGPCGKYNAMVLEL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGS-GDGIPQVYYFGPCGKYNAMVLEL 118
Query: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
LGPSLEDLFDLCDRTF+LKTVLMIAIQL+SRMEYVHSKNLIYRDVKPENFLIGR GNK +
Sbjct: 119 LGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQ 178
Query: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM
Sbjct: 179 QVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 238
Query: 241 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE 300
FMYFLRGSLPWQGLKADTLKERYQKIGDTKR TPIE LCENFP EMATYLRYVRRLDFFE
Sbjct: 239 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFE 297
Query: 301 KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP 360
KPDY+YLR LFTDLF++KGY FDY YDW+G+ +PTPVG+V D S+ RE+H HRD+
Sbjct: 298 KPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSS-NREAHQHRDKM 356
Query: 361 SQQQ------------------PLRN-----------QVVSSTNGELNVDDPTGAHSNAP 391
Q + LR QVVSSTNGELN DDPT SNAP
Sbjct: 357 QQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAP 416
Query: 392 ITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK 422
ITA EVEV++E KCCCFFKR+++KT QRHK
Sbjct: 417 ITAPTEVEVMDETKCCCFFKRRKRKTIQRHK 447
>gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens]
Length = 455
Score = 675 bits (1741), Expect = 0.0
Identities = 344/459 (74%), Positives = 374/459 (81%), Gaps = 41/459 (8%)
Query: 1 MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL 60
M++ ++KD+ + RS H +R +GSSSS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 1 MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSS-GVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 61 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQLGS G+G+PQVYYFGPCGKYNAMVLEL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGS-GDGIPQVYYFGPCGKYNAMVLEL 118
Query: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
LGPSLEDLFDLCDRTF+LKTVLMIAIQL+SRMEYVHSKNLIYRDVKPENFLIGR GNK +
Sbjct: 119 LGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQ 178
Query: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM
Sbjct: 179 QVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 238
Query: 241 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE 300
FMYFLRGSLPWQGLKADTLKERYQKIGDTKR TPIE LCENFP EMATYLRYVRRLDFFE
Sbjct: 239 FMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFE 297
Query: 301 KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP 360
KPDY+YLR LFTDLF++KGY FDY YDW+G+ +PTPVG+V D S+ RE+H HRD+
Sbjct: 298 KPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSS-NREAHQHRDKM 356
Query: 361 SQQQ------------------PLRN-----------QVVSSTNGELNVDDPTGAHSNAP 391
Q + LR QVVSSTNGELN DDPT SNAP
Sbjct: 357 QQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAP 416
Query: 392 ITAHAEVEVVEEAK--------CCCFFKRKRKKTAQRHK 422
ITA EVEV++E CCCFFKR+++KT QRHK
Sbjct: 417 ITAPTEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK 455
>gi|23199991 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 365 bits (936), Expect = e-101
Identities = 181/352 (51%), Positives = 248/352 (70%), Gaps = 15/352 (4%)
Query: 38 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSA 97
L VG +R+G+KIG G+FG++ LG N+ + E VAIKLE +K++ PQLH+E +FYK +
Sbjct: 3 LRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMM-QG 61
Query: 98 GEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHS 157
G G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q++SR+EY+HS
Sbjct: 62 GVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 158 KNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 217
KN I+RDVKP+NFL+G KK ++++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 122 KNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARY 179
Query: 218 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEA 277
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIE
Sbjct: 180 ASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEV 239
Query: 278 LCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPV 337
LC+ +P E +TYL + R L F +KPDY YLR LF +LF ++G+++DY +DW
Sbjct: 240 LCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--------- 290
Query: 338 GSVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSN 389
++ +A E R +++ Q+ S L PTGA +N
Sbjct: 291 ---NMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATAN 339
>gi|4503093 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 365 bits (936), Expect = e-101
Identities = 181/352 (51%), Positives = 248/352 (70%), Gaps = 15/352 (4%)
Query: 38 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSA 97
L VG +R+G+KIG G+FG++ LG N+ + E VAIKLE +K++ PQLH+E +FYK +
Sbjct: 3 LRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMM-QG 61
Query: 98 GEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHS 157
G G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q++SR+EY+HS
Sbjct: 62 GVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 158 KNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 217
KN I+RDVKP+NFL+G KK ++++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 122 KNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARY 179
Query: 218 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEA 277
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIE
Sbjct: 180 ASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEV 239
Query: 278 LCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPV 337
LC+ +P E +TYL + R L F +KPDY YLR LF +LF ++G+++DY +DW
Sbjct: 240 LCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--------- 290
Query: 338 GSVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSN 389
++ +A E R +++ Q+ S L PTGA +N
Sbjct: 291 ---NMLKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATAN 339
>gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens]
Length = 409
Score = 359 bits (922), Expect = 2e-99
Identities = 169/291 (58%), Positives = 227/291 (78%), Gaps = 3/291 (1%)
Query: 38 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSA 97
L VG +R+G+KIG G+FG++ LG ++ E VAIKLE +K++ PQLH+E + YK +
Sbjct: 3 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM-QG 61
Query: 98 GEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHS 157
G G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q++SR+EY+HS
Sbjct: 62 GVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 158 KNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 217
KN I+RDVKP+NFL+G KK ++++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 122 KNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARY 179
Query: 218 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEA 277
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIE
Sbjct: 180 ASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEV 239
Query: 278 LCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDW 328
LC+ +P E ATYL + R L F +KPDY YLR LF +LF ++G+++DY +DW
Sbjct: 240 LCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
>gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]
Length = 415
Score = 359 bits (922), Expect = 2e-99
Identities = 169/291 (58%), Positives = 227/291 (78%), Gaps = 3/291 (1%)
Query: 38 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSA 97
L VG +R+G+KIG G+FG++ LG ++ E VAIKLE +K++ PQLH+E + YK +
Sbjct: 3 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM-QG 61
Query: 98 GEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHS 157
G G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q++SR+EY+HS
Sbjct: 62 GVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 158 KNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 217
KN I+RDVKP+NFL+G KK ++++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 122 KNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARY 179
Query: 218 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEA 277
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIE
Sbjct: 180 ASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEV 239
Query: 278 LCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDW 328
LC+ +P E ATYL + R L F +KPDY YLR LF +LF ++G+++DY +DW
Sbjct: 240 LCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
Length = 337
Score = 332 bits (852), Expect = 3e-91
Identities = 166/302 (54%), Positives = 216/302 (71%), Gaps = 7/302 (2%)
Query: 29 SGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEY 88
+ SS S +VG +++ +KIG G+FG++ L N+ E VA+KLE K+R PQL E
Sbjct: 2 ASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYES 61
Query: 89 RFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQL 148
+ YK L G G+P + ++G YN +V++LLGPSLEDLF+ C R FT+KTVLM+A Q+
Sbjct: 62 KLYKIL-QGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM 120
Query: 149 LSRMEYVHSKNLIYRDVKPENFL--IGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYR 206
+SR+EYVH+KN I+RD+KP+NFL IGR NK + +IDFGLAK+Y D T++HIPYR
Sbjct: 121 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNK----LFLIDFGLAKKYRDNRTRQHIPYR 176
Query: 207 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKI 266
E K+LTGTARY SIN HLG EQSRRDD+E+LG++ MYF R SLPWQGLKA T K++Y+KI
Sbjct: 177 EDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKI 236
Query: 267 GDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAY 326
+ K +TP+E LC+ FP E A YL Y R L F E PDY YLR LF LF + +DY +
Sbjct: 237 SEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTF 296
Query: 327 DW 328
DW
Sbjct: 297 DW 298
>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
Length = 365
Score = 322 bits (826), Expect = 3e-88
Identities = 166/326 (50%), Positives = 217/326 (66%), Gaps = 27/326 (8%)
Query: 29 SGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEY 88
+ SS S +VG +++ +KIG G+FG++ L N+ E VA+KLE K+R PQL E
Sbjct: 2 ASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYES 61
Query: 89 RFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQL 148
+ YK L G G+P + ++G YN +V++LLGPSLEDLF+ C R FT+KTVLM+A Q+
Sbjct: 62 KLYKIL-QGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM 120
Query: 149 LSRMEYVHSKNLIYRDVKPENFL--IGRQGNK------------------------KEHV 182
+SR+EYVH+KN I+RD+KP+NFL IGR NK +
Sbjct: 121 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQ 180
Query: 183 IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFM 242
+ +IDFGLAK+Y D T++HIPYRE K+LTGTARY SIN HLG EQSRRDD+E+LG++ M
Sbjct: 181 LFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLM 240
Query: 243 YFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKP 302
YF R SLPWQGLKA T K++Y+KI + K +TP+E LC+ FP E A YL Y R L F E P
Sbjct: 241 YFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAP 300
Query: 303 DYEYLRTLFTDLFEKKGYTFDYAYDW 328
DY YLR LF LF + +DY +DW
Sbjct: 301 DYMYLRQLFRILFRTLNHQYDYTFDW 326
>gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens]
Length = 337
Score = 319 bits (817), Expect = 3e-87
Identities = 160/302 (52%), Positives = 212/302 (70%), Gaps = 7/302 (2%)
Query: 29 SGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEY 88
+ +S S L+VG +++ +KIG G+FG++ LG E VA+KLE K + PQL E
Sbjct: 2 TNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYES 61
Query: 89 RFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQL 148
+ Y L G G+P ++++G N +V++LLGPSLEDLF+ C R FT+KTVLM+A Q+
Sbjct: 62 KLYTIL-QGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM 120
Query: 149 LSRMEYVHSKNLIYRDVKPENFLIG--RQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYR 206
+SR+EYVH+KN ++RD+KP+NFL+G R NK + +IDFGLAK+Y D T++HIPYR
Sbjct: 121 ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNK----LFLIDFGLAKKYRDNRTRQHIPYR 176
Query: 207 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKI 266
E K L GT RY SIN HLG EQSRRDD+E+LG++FMYF R SLPWQGLKA T K++Y+KI
Sbjct: 177 EDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKI 236
Query: 267 GDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAY 326
+ K +TP+E LC+ FP E A YL Y R L F E PDY YLR LF LF + +DY +
Sbjct: 237 SEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTF 296
Query: 327 DW 328
DW
Sbjct: 297 DW 298
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 163 bits (413), Expect = 2e-40
Identities = 104/308 (33%), Positives = 163/308 (52%), Gaps = 20/308 (6%)
Query: 29 SGSSSSSGVL----MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQL 84
SG + +L +V ++V KKIG G FGE+ +L T E VA+K+E + L
Sbjct: 15 SGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVL 74
Query: 85 HLEYRFYKQLGSAGEGLPQVYYFGPCG---KYNAMVLELLGPSLEDLFDLCDR-TFTLKT 140
+E K+L +G V F CG K+N +V++L G +L DL R TFTL T
Sbjct: 75 KMEVAVLKKL----QGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLST 130
Query: 141 VLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETK 200
L + Q+L +E +HS ++RD+KP NF +GR + +++DFGLA++Y + T
Sbjct: 131 TLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKC-YMLDFGLARQYTNT-TG 188
Query: 201 KHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLK 260
P R GT RY S+N H +E R DDL +L +M + F G LPW+ +K
Sbjct: 189 DVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK--- 245
Query: 261 ERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGY 320
+++G K L ++ P E +L ++ LD+F KPDY+ + ++F + +++G
Sbjct: 246 ---EQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGI 302
Query: 321 TFDYAYDW 328
+ A+DW
Sbjct: 303 AENEAFDW 310
>gi|116812624 tau tubulin kinase 2 [Homo sapiens]
Length = 1244
Score = 153 bits (386), Expect = 3e-37
Identities = 99/308 (32%), Positives = 159/308 (51%), Gaps = 20/308 (6%)
Query: 29 SGSSSSSGVLMVG----PNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQL 84
SG +L VG ++V +KIG G FGE+ ++ T E VA+K+E + L
Sbjct: 2 SGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVL 61
Query: 85 HLEYRFYKQLGSAGEGLPQVYYFGPCGK---YNAMVLELLGPSLEDLFDLCDR-TFTLKT 140
+E K+L +G V F CG+ +N +V++L G +L DL R TFT+ T
Sbjct: 62 KMEVAVLKKL----QGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTIST 117
Query: 141 VLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETK 200
L + Q+L +E +HS ++RD+KP NF +GR + +++DFGLA+++ +
Sbjct: 118 TLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKC-YMLDFGLARQFTNSCGD 176
Query: 201 KHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLK 260
P R GT RY SIN H +E R DDL +L +M + F+ G LPW+ +K
Sbjct: 177 VRPP-RAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDK--- 232
Query: 261 ERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGY 320
+++G K + ++ P E + +L ++ LD+F KPDY+ L ++F + + G
Sbjct: 233 ---EQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGV 289
Query: 321 TFDYAYDW 328
+DW
Sbjct: 290 IESDPFDW 297
>gi|4507903 vaccinia related kinase 1 [Homo sapiens]
Length = 396
Score = 120 bits (300), Expect = 3e-27
Identities = 83/297 (27%), Positives = 141/297 (47%), Gaps = 30/297 (10%)
Query: 39 MVGPNFRVGKKIGCGNFG-----ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQ 93
M ++VG IG G FG ++ +++ ++ +K+EP S L E +FY++
Sbjct: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQR 89
Query: 94 LGSAGE-------------GLPQVYYFGPCGK----YNAMVLELLGPSLEDLFDLCDRTF 136
+ G+P+ + G K Y M+++ G L+ +++ + F
Sbjct: 90 AAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRF 149
Query: 137 TLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYID 196
+ KTVL +++++L +EY+H ++ D+K N L+ K ++++D+GLA Y
Sbjct: 150 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY---KNPDQVYLVDYGLAYRYCP 206
Query: 197 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA 256
K + GT + SI+ H G SRR DLE LG+ + +L G LPW+
Sbjct: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
Query: 257 DTLKERYQKIGDTKRNTPIEALC---ENFPEEMATYLRYVRRLDFFEKPDYEYLRTL 310
D R KI + + C +N P E+A Y+ V+ LD+ EKP YE LR +
Sbjct: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDI 323
>gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens]
Length = 396
Score = 97.4 bits (241), Expect = 2e-20
Identities = 96/348 (27%), Positives = 149/348 (42%), Gaps = 45/348 (12%)
Query: 39 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLG 95
M G + +GKKIG G FG + L E A +K+E + P L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 96 SAG-------------EGLPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 138
G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 139 KTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPE 198
TVL + I++L +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 199 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 251
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 252 ---QGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLR 308
Q K + L E Q + + P + C E+A +L L + EKP+Y+ L+
Sbjct: 258 VAVQTAKTNLLDELPQSV---LKWAPSGSSC----CEIAQFLVCAHSLAYDEKPNYQALK 310
Query: 309 TLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTH 356
+ G D++ + TP S VDS +A + + H
Sbjct: 311 KILNPHGIPLG-PLDFSTKGQSINVHTP-NSQKVDSQKAATKQVNKAH 356
>gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]
Length = 485
Score = 97.4 bits (241), Expect = 2e-20
Identities = 96/348 (27%), Positives = 149/348 (42%), Gaps = 45/348 (12%)
Query: 39 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLG 95
M G + +GKKIG G FG + L E A +K+E + P L E +FY+++
Sbjct: 1 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 58
Query: 96 SAG-------------EGLPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 138
G+P Y G Y MV+E LG L+ + + TF
Sbjct: 59 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 117
Query: 139 KTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPE 198
TVL + I++L +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 118 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 174
Query: 199 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 251
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 175 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 234
Query: 252 ---QGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLR 308
Q K + L E Q + + P + C E+A +L L + EKP+Y+ L+
Sbjct: 235 VAVQTAKTNLLDELPQSV---LKWAPSGSSC----CEIAQFLVCAHSLAYDEKPNYQALK 287
Query: 309 TLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTH 356
+ G D++ + TP S VDS +A + + H
Sbjct: 288 KILNPHGIPLG-PLDFSTKGQSINVHTP-NSQKVDSQKAATKQVNKAH 333
>gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 97.4 bits (241), Expect = 2e-20
Identities = 96/348 (27%), Positives = 149/348 (42%), Gaps = 45/348 (12%)
Query: 39 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLG 95
M G + +GKKIG G FG + L E A +K+E + P L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 96 SAG-------------EGLPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 138
G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 139 KTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPE 198
TVL + I++L +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 199 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 251
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 252 ---QGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLR 308
Q K + L E Q + + P + C E+A +L L + EKP+Y+ L+
Sbjct: 258 VAVQTAKTNLLDELPQSV---LKWAPSGSSC----CEIAQFLVCAHSLAYDEKPNYQALK 310
Query: 309 TLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTH 356
+ G D++ + TP S VDS +A + + H
Sbjct: 311 KILNPHGIPLG-PLDFSTKGQSINVHTP-NSQKVDSQKAATKQVNKAH 356
>gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 97.4 bits (241), Expect = 2e-20
Identities = 96/348 (27%), Positives = 149/348 (42%), Gaps = 45/348 (12%)
Query: 39 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLG 95
M G + +GKKIG G FG + L E A +K+E + P L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 96 SAG-------------EGLPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 138
G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 139 KTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPE 198
TVL + I++L +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 199 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 251
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 252 ---QGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLR 308
Q K + L E Q + + P + C E+A +L L + EKP+Y+ L+
Sbjct: 258 VAVQTAKTNLLDELPQSV---LKWAPSGSSC----CEIAQFLVCAHSLAYDEKPNYQALK 310
Query: 309 TLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTH 356
+ G D++ + TP S VDS +A + + H
Sbjct: 311 KILNPHGIPLG-PLDFSTKGQSINVHTP-NSQKVDSQKAATKQVNKAH 356
>gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 97.4 bits (241), Expect = 2e-20
Identities = 96/348 (27%), Positives = 149/348 (42%), Gaps = 45/348 (12%)
Query: 39 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLG 95
M G + +GKKIG G FG + L E A +K+E + P L E +FY+++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 96 SAG-------------EGLPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 138
G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 139 KTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPE 198
TVL + I++L +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 199 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 251
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 252 ---QGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLR 308
Q K + L E Q + + P + C E+A +L L + EKP+Y+ L+
Sbjct: 258 VAVQTAKTNLLDELPQSV---LKWAPSGSSC----CEIAQFLVCAHSLAYDEKPNYQALK 310
Query: 309 TLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTH 356
+ G D++ + TP S VDS +A + + H
Sbjct: 311 KILNPHGIPLG-PLDFSTKGQSINVHTP-NSQKVDSQKAATKQVNKAH 356
>gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]
Length = 390
Score = 88.2 bits (217), Expect = 1e-17
Identities = 71/251 (28%), Positives = 113/251 (45%), Gaps = 23/251 (9%)
Query: 116 MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQ 175
MV+E LG L+ + + TF TVL + I++L +EY+H ++ D+K N L+G
Sbjct: 1 MVMERLGIDLQKISGQ-NGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY- 58
Query: 176 GNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLE 235
K +++ D+GL+ Y K K GT + S++ H G SRR D+E
Sbjct: 59 --KNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVE 116
Query: 236 ALGHMFMYFLRGSLPW----------QGLKADTLKERYQKIGDTKRNTPIEALCENFPEE 285
LG+ + +L G LPW Q K + L E Q + + P + C E
Sbjct: 117 ILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSV---LKWAPSGSSC----CE 169
Query: 286 MATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSG 345
+A +L L + EKP+Y+ L+ + G D++ + TP S VDS
Sbjct: 170 IAQFLVCAHSLAYDEKPNYQALKKILNPHGIPLG-PLDFSTKGQSINVHTP-NSQKVDSQ 227
Query: 346 ASAITRESHTH 356
+A + + H
Sbjct: 228 KAATKQVNKAH 238
>gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens]
Length = 424
Score = 85.5 bits (210), Expect = 8e-17
Identities = 63/228 (27%), Positives = 106/228 (46%), Gaps = 14/228 (6%)
Query: 112 KYNAMVLELLGPSLEDLFDLCDR-TFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENF 170
KY +VL LG SL+ D+ + + ++VL +A +LL +E++H ++ +V EN
Sbjct: 203 KYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENI 262
Query: 171 LIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYRE--HKSLTGTARYMSINTHLGKEQ 228
+ + + + + +G A Y + KH+ Y E G ++S++ H G
Sbjct: 263 FVDPEDQSQ---VTLAGYGFAFRYCP--SGKHVAYVEGSRSPHEGDLEFISMDLHKGCGP 317
Query: 229 SRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENF---PEE 285
SRR DL++LG+ + +L G LPW +T QK + P C ++ E
Sbjct: 318 SRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSET 377
Query: 286 MATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPI 333
+ YL+ V L + EKP Y LR L + + YD +G P+
Sbjct: 378 LQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVS---PYDPIGLPM 422
>gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]
Length = 474
Score = 85.5 bits (210), Expect = 8e-17
Identities = 63/228 (27%), Positives = 106/228 (46%), Gaps = 14/228 (6%)
Query: 112 KYNAMVLELLGPSLEDLFDLCDR-TFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENF 170
KY +VL LG SL+ D+ + + ++VL +A +LL +E++H ++ +V EN
Sbjct: 253 KYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENI 312
Query: 171 LIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYRE--HKSLTGTARYMSINTHLGKEQ 228
+ + + + + +G A Y + KH+ Y E G ++S++ H G
Sbjct: 313 FVDPEDQSQ---VTLAGYGFAFRYCP--SGKHVAYVEGSRSPHEGDLEFISMDLHKGCGP 367
Query: 229 SRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENF---PEE 285
SRR DL++LG+ + +L G LPW +T QK + P C ++ E
Sbjct: 368 SRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSET 427
Query: 286 MATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPI 333
+ YL+ V L + EKP Y LR L + + YD +G P+
Sbjct: 428 LQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVS---PYDPIGLPM 472
>gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform 1
[Homo sapiens]
Length = 556
Score = 71.6 bits (174), Expect = 1e-12
Identities = 63/223 (28%), Positives = 104/223 (46%), Gaps = 33/223 (14%)
Query: 43 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEP-------------IKSRAPQLHLEYR 89
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 90 FYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLL 149
F+ +L + + YFG N +L+ + + + C R +T +++
Sbjct: 141 FFVKLYFTFQD-DEKLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIV 190
Query: 150 SRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHK 209
S +EY+H K +I+RD+KPEN L+ N+ H I I DFG AK + PE+K+
Sbjct: 191 SALEYLHGKGIIHRDLKPENILL----NEDMH-IQITDFGTAK-VLSPESKQ----ARAN 240
Query: 210 SLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 252
S GTA+Y+S K + DL ALG + + G P++
Sbjct: 241 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 283
>gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent
protein kinase-1 [Homo sapiens]
Length = 471
Score = 71.6 bits (174), Expect = 1e-12
Identities = 63/223 (28%), Positives = 105/223 (47%), Gaps = 33/223 (14%)
Query: 43 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEP-------------IKSRAPQLHLEYR 89
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 100 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 159
Query: 90 FYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLL 149
F+ +L + ++Y FG N +L+ + + + C R +T +++
Sbjct: 160 FFVKLYFTFQTTRRLY-FGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIV 209
Query: 150 SRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHK 209
S +EY+H K +I+RD+KPEN L+ N+ H I I DFG AK + PE+K+
Sbjct: 210 SALEYLHGKGIIHRDLKPENILL----NEDMH-IQITDFGTAK-VLSPESKQ----ARAN 259
Query: 210 SLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 252
S GTA+Y+S K + DL ALG + + G P++
Sbjct: 260 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 302
>gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo
sapiens]
Length = 396
Score = 71.6 bits (174), Expect = 1e-12
Identities = 63/223 (28%), Positives = 104/223 (46%), Gaps = 33/223 (14%)
Query: 43 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEP-------------IKSRAPQLHLEYR 89
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 54 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 113
Query: 90 FYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLL 149
F+ +L + + YFG N +L+ + + + C R +T +++
Sbjct: 114 FFVKLYFTFQD-DEKLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIV 163
Query: 150 SRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHK 209
S +EY+H K +I+RD+KPEN L+ N+ H I I DFG AK + PE+K+
Sbjct: 164 SALEYLHGKGIIHRDLKPENILL----NEDMH-IQITDFGTAK-VLSPESKQ----ARAN 213
Query: 210 SLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 252
S GTA+Y+S K + DL ALG + + G P++
Sbjct: 214 SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 256
>gi|4826948 protein kinase, X-linked [Homo sapiens]
Length = 358
Score = 70.1 bits (170), Expect = 4e-12
Identities = 66/251 (26%), Positives = 109/251 (43%), Gaps = 25/251 (9%)
Query: 7 EKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYT 66
E D R+ + A C P S V + +F +G G FG + L K
Sbjct: 13 ESDSRKVAEETPDGAPALCPSPEALSPEPPVYSL-QDFDTLATVGTGTFGRVHLVKEKTA 71
Query: 67 NEYVAIKLEPIKS-----RAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELL 121
+ A+K+ I + +H E K++ L ++++ ++ M++E +
Sbjct: 72 KHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPF--LIRLFWTWHDERFLYMLMEYV 129
Query: 122 GPSLEDLFDLCDR-TFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
P E L +R F+ T L + +++ +EY+HSK ++YRD+KPEN L+ R G+
Sbjct: 130 -PGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGH--- 185
Query: 181 HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM 240
I + DFG AK+ +D +L GT Y++ K R D ALG +
Sbjct: 186 --IKLTDFGFAKKLVD----------RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGIL 233
Query: 241 FMYFLRGSLPW 251
L G P+
Sbjct: 234 IFEMLSGFPPF 244
>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 68.2 bits (165), Expect = 1e-11
Identities = 60/238 (25%), Positives = 108/238 (45%), Gaps = 26/238 (10%)
Query: 43 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE--- 99
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 100 -GLPQVYYFGPCGKYNAMVLEL--LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVH 156
+ ++Y + ++LE LG +L L F + +L + + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 157 SKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 216
SK +I+RD+KPEN L+G G K I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAGELK-----IADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 217 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTP 274
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 68.2 bits (165), Expect = 1e-11
Identities = 60/238 (25%), Positives = 108/238 (45%), Gaps = 26/238 (10%)
Query: 43 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE--- 99
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 100 -GLPQVYYFGPCGKYNAMVLEL--LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVH 156
+ ++Y + ++LE LG +L L F + +L + + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 157 SKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 216
SK +I+RD+KPEN L+G G K I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAGELK-----IADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 217 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTP 274
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,760,850
Number of Sequences: 37866
Number of extensions: 793704
Number of successful extensions: 3195
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 482
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 2209
Number of HSP's gapped (non-prelim): 850
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.