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Search of human proteins with 9506611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9506611 guanine nucleotide binding protein-like 3
(nucleolar)-like [Homo sapiens]
(582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9506611 guanine nucleotide binding protein-like 3 (nucleolar)... 1169 0.0
gi|45643129 guanine nucleotide binding protein-like 3 isoform 2 ... 282 7e-76
gi|45643127 guanine nucleotide binding protein-like 3 isoform 2 ... 282 7e-76
gi|45593130 guanine nucleotide binding protein-like 3 isoform 1 ... 282 7e-76
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)... 179 8e-45
gi|223029424 large subunit GTPase 1 [Homo sapiens] 84 4e-16
gi|93277113 GTP_binding protein [Homo sapiens] 78 2e-14
gi|38788319 guanine nucleotide binding protein-like 1 [Homo sapi... 65 1e-10
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.005
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 40 0.005
gi|111955139 GTP-binding protein 10 isoform 2 [Homo sapiens] 40 0.006
gi|148746195 trichohyalin [Homo sapiens] 39 0.010
gi|193082988 GTP binding protein 3 (mitochondrial) isoform IV [H... 39 0.010
gi|4758796 developmentally regulated GTP binding protein 1 [Homo... 39 0.010
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 39 0.013
gi|58761500 Obg-like ATPase 1 isoform 1 [Homo sapiens] 39 0.013
gi|193082993 GTP binding protein 3 (mitochondrial) isoform III [... 39 0.017
gi|193082991 GTP binding protein 3 (mitochondrial) isoform V [Ho... 39 0.017
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 38 0.022
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 38 0.022
gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens] 38 0.029
gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens] 38 0.029
gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens] 38 0.029
gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens] 38 0.029
gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens] 38 0.029
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 37 0.038
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 37 0.038
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 37 0.038
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 37 0.050
gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [... 37 0.050
>gi|9506611 guanine nucleotide binding protein-like 3
(nucleolar)-like [Homo sapiens]
Length = 582
Score = 1169 bits (3025), Expect = 0.0
Identities = 582/582 (100%), Positives = 582/582 (100%)
Query: 1 MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELK 60
MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELK
Sbjct: 1 MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELK 60
Query: 61 KKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEAT 120
KKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEAT
Sbjct: 61 KKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEAT 120
Query: 121 RKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPK 180
RKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPK
Sbjct: 121 RKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPK 180
Query: 181 EVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVL 240
EVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVL
Sbjct: 181 EVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVL 240
Query: 241 GNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIR 300
GNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIR
Sbjct: 241 GNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIR 300
Query: 301 LLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTE 360
LLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTE
Sbjct: 301 LLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTE 360
Query: 361 HFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKE 420
HFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKE
Sbjct: 361 HFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKE 420
Query: 421 MTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTV 480
MTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTV
Sbjct: 421 MTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTV 480
Query: 481 YKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQA 540
YKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQA
Sbjct: 481 YKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQA 540
Query: 541 LASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD 582
LASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD
Sbjct: 541 LASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD 582
>gi|45643129 guanine nucleotide binding protein-like 3 isoform 2
[Homo sapiens]
Length = 537
Score = 282 bits (721), Expect = 7e-76
Identities = 162/425 (38%), Positives = 256/425 (60%), Gaps = 11/425 (2%)
Query: 18 HKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQ 77
H+K+ + AK+ G K K P P+ + REAEL+K+ +EE++++Q+ R++
Sbjct: 17 HRKLR----KEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQK 72
Query: 78 ERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDV 137
E +K+R +E+ D+ E KE L + + + ++K Y +E +KV+E SDV
Sbjct: 73 ELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDV 131
Query: 138 ILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTV 197
+LEVLDARDPLGCRC Q+EEA++++ G KKLVL+LNK DLVPKE +E WL+YL+ ELPTV
Sbjct: 132 VLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVLILNKSDLVPKENLESWLNYLKKELPTV 190
Query: 198 AFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGV 257
F+AST+ + K V + + + +S+ CFG E L ++LG + IRVGV
Sbjct: 191 VFRASTKPKDKGKITKRVKAKK-NAAPFRSEVCFGKEGLWKLLGGFQET--CSKAIRVGV 247
Query: 258 VGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGP-NSEVG 316
+G PNVGKSS+INSLK+ + C+VG G+T+ MQ V LDK I ++D+P + P NS
Sbjct: 248 IGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSA 307
Query: 317 TILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKG 376
LR+ ++ + P+ IL + + ++ Y V G++ + F T +A R G +KG
Sbjct: 308 LALRSPASIE-VVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKG 366
Query: 377 GLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANED 436
G+ + E AAK + ++W +++Y PP + T P + + IV +M F++E+ E+ N
Sbjct: 367 GIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQ 426
Query: 437 TMECL 441
++ +
Sbjct: 427 SIRAI 431
>gi|45643127 guanine nucleotide binding protein-like 3 isoform 2
[Homo sapiens]
Length = 537
Score = 282 bits (721), Expect = 7e-76
Identities = 162/425 (38%), Positives = 256/425 (60%), Gaps = 11/425 (2%)
Query: 18 HKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQ 77
H+K+ + AK+ G K K P P+ + REAEL+K+ +EE++++Q+ R++
Sbjct: 17 HRKLR----KEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQK 72
Query: 78 ERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDV 137
E +K+R +E+ D+ E KE L + + + ++K Y +E +KV+E SDV
Sbjct: 73 ELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDV 131
Query: 138 ILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTV 197
+LEVLDARDPLGCRC Q+EEA++++ G KKLVL+LNK DLVPKE +E WL+YL+ ELPTV
Sbjct: 132 VLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVLILNKSDLVPKENLESWLNYLKKELPTV 190
Query: 198 AFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGV 257
F+AST+ + K V + + + +S+ CFG E L ++LG + IRVGV
Sbjct: 191 VFRASTKPKDKGKITKRVKAKK-NAAPFRSEVCFGKEGLWKLLGGFQET--CSKAIRVGV 247
Query: 258 VGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGP-NSEVG 316
+G PNVGKSS+INSLK+ + C+VG G+T+ MQ V LDK I ++D+P + P NS
Sbjct: 248 IGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSA 307
Query: 317 TILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKG 376
LR+ ++ + P+ IL + + ++ Y V G++ + F T +A R G +KG
Sbjct: 308 LALRSPASIE-VVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKG 366
Query: 377 GLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANED 436
G+ + E AAK + ++W +++Y PP + T P + + IV +M F++E+ E+ N
Sbjct: 367 GIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQ 426
Query: 437 TMECL 441
++ +
Sbjct: 427 SIRAI 431
>gi|45593130 guanine nucleotide binding protein-like 3 isoform 1
[Homo sapiens]
Length = 549
Score = 282 bits (721), Expect = 7e-76
Identities = 162/425 (38%), Positives = 256/425 (60%), Gaps = 11/425 (2%)
Query: 18 HKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQ 77
H+K+ + AK+ G K K P P+ + REAEL+K+ +EE++++Q+ R++
Sbjct: 29 HRKLR----KEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQK 84
Query: 78 ERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDV 137
E +K+R +E+ D+ E KE L + + + ++K Y +E +KV+E SDV
Sbjct: 85 ELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDV 143
Query: 138 ILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTV 197
+LEVLDARDPLGCRC Q+EEA++++ G KKLVL+LNK DLVPKE +E WL+YL+ ELPTV
Sbjct: 144 VLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVLILNKSDLVPKENLESWLNYLKKELPTV 202
Query: 198 AFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGV 257
F+AST+ + K V + + + +S+ CFG E L ++LG + IRVGV
Sbjct: 203 VFRASTKPKDKGKITKRVKAKK-NAAPFRSEVCFGKEGLWKLLGGFQET--CSKAIRVGV 259
Query: 258 VGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGP-NSEVG 316
+G PNVGKSS+INSLK+ + C+VG G+T+ MQ V LDK I ++D+P + P NS
Sbjct: 260 IGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSA 319
Query: 317 TILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKG 376
LR+ ++ + P+ IL + + ++ Y V G++ + F T +A R G +KG
Sbjct: 320 LALRSPASIE-VVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKG 378
Query: 377 GLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANED 436
G+ + E AAK + ++W +++Y PP + T P + + IV +M F++E+ E+ N
Sbjct: 379 GIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQ 438
Query: 437 TMECL 441
++ +
Sbjct: 439 SIRAI 443
>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
[Homo sapiens]
Length = 731
Score = 179 bits (453), Expect = 8e-45
Identities = 111/334 (33%), Positives = 171/334 (51%), Gaps = 32/334 (9%)
Query: 122 KAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKE 181
K + E KV++ SDV+++VLDARDP+G R +E + + + K L+ VLNK DLVP
Sbjct: 204 KRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTW 263
Query: 182 VVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLG 241
++W+ L + PT+AF AS + FG +++L
Sbjct: 264 ATKRWVAVLSQDYPTLAFHASLTNP------------------------FGKGAFIQLLR 299
Query: 242 NYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRL 301
+ +L + I VG +G PNVGKSS+IN+L+ + C+V + G TK Q + L + I L
Sbjct: 300 QFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFL 359
Query: 302 LDAPGIV-PGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTE 360
+D PG+V P +SE +L+ V V+K+ P + +L+R E IS Y + ++ E
Sbjct: 360 IDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAE 419
Query: 361 HFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPP------ATHTLPTHLS 414
FL +A R GK KGG + K VL DW G+I F++ PP A LP+ S
Sbjct: 420 DFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSS-S 478
Query: 415 AEIVKEMTEVFDIEDTEQANEDTMECLATGESDE 448
E+V E + E+ + + E + E++E
Sbjct: 479 LEVVPEAAQNNPGEEVTETAGEGSESIIKEETEE 512
>gi|223029424 large subunit GTPase 1 [Homo sapiens]
Length = 658
Score = 84.0 bits (206), Expect = 4e-16
Identities = 52/165 (31%), Positives = 83/165 (50%), Gaps = 13/165 (7%)
Query: 253 IRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGP- 311
+ VG+VG PNVGKSS IN++ ++ SV A PG TK Q +Y++ + L D PG+V
Sbjct: 387 LTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSF 446
Query: 312 -NSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGF-----------QTT 359
+++ + + ++ D V PV + Q + YG++ T+
Sbjct: 447 VSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTS 506
Query: 360 EHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPP 404
E LTA + G G Q ++A+ +L D+VSGK+ + PPP
Sbjct: 507 EELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPP 551
Score = 55.5 bits (132), Expect = 1e-07
Identities = 26/76 (34%), Positives = 45/76 (59%)
Query: 124 YYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVV 183
++++ +V+E SD++++++DAR+PL RC +E V NK+ V+++NK DL+ E
Sbjct: 163 FWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQR 222
Query: 184 EKWLDYLRNELPTVAF 199
W Y E V F
Sbjct: 223 SAWAMYFEKEDVKVIF 238
>gi|93277113 GTP_binding protein [Homo sapiens]
Length = 334
Score = 78.2 bits (191), Expect = 2e-14
Identities = 83/270 (30%), Positives = 128/270 (47%), Gaps = 48/270 (17%)
Query: 126 KEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEK 185
K+ + ++ D I+EV DAR PL R +E + G K +LVLNK+DL +K
Sbjct: 40 KKMQSSLKLVDCIIEVHDARIPLSGRNPLFQETL----GLKPHLLVLNKMDLADLTEQQK 95
Query: 186 WLDYLRNE-LPTVAFKASTQHQ-VKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNY 243
+ +L E L V F + + VK + + +E + +S ENL Y
Sbjct: 96 IMQHLEGEGLKNVIFTNCVKDENVKQI------IPMVTELIGRSHRYHRKENL-----EY 144
Query: 244 CRLGEVRTHIRVGVVGLPNVGKSSLINSLKR-----SRACSVGAVPGITK-FMQEVYLDK 297
C + V+G+PNVGKSSLINSL+R +A VG PGIT+ M ++ + +
Sbjct: 145 C----------IMVIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSKIQVSE 194
Query: 298 --FIRLLDAPGIVPGPNSE----------VGTILRNCVHVQKLADPVTPVETILQRCNLE 345
+ LLD PG++ P E GT+L + V + +AD + + T+ +
Sbjct: 195 RPLMFLLDTPGVL-APRIESVETGLKLALCGTVLDHLVGEETMADYL--LYTLNKHQRFG 251
Query: 346 EISNYYGVSGFQTTEHFLTAVAHRLGKKKK 375
+ +Y S E L +VA +LGK +K
Sbjct: 252 YVQHYGLGSACDNVERVLKSVAVKLGKTQK 281
>gi|38788319 guanine nucleotide binding protein-like 1 [Homo
sapiens]
Length = 607
Score = 65.5 bits (158), Expect = 1e-10
Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 22/214 (10%)
Query: 253 IRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIV-PGP 311
+ +G VG PNVGKSSLIN L + SV PG T++ Q +L ++L D PG++ P
Sbjct: 361 VTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSL 420
Query: 312 NSEVGTILRNCVHVQKLADPVT---------PVETI--LQRCNLEEISNYYGVSGFQTTE 360
+L + ++ +P T PV+ + L+ E+ S + + E
Sbjct: 421 LPRQLQVLAGIYPIAQIQEPYTAVGYLASRIPVQALLHLRHPEAEDPSAEHPWCAWDICE 480
Query: 361 HFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPA----THTLPTH-LSA 415
+ ++ K + +Y +AA ++L V G++S PP T +H +
Sbjct: 481 AWAEKRGYKTAKAARNDVY---RAANSLLRLAVDGRLSLCFHPPGYSEQKGTWESHPETT 537
Query: 416 EIVKEMTEVFDIEDTEQANEDTM--ECLATGESD 447
E+V V D E+ E+ + C GE D
Sbjct: 538 ELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEED 571
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 125 YKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVE 184
+++ +V+E SD++L + D R P+ + E V G LVLVLNK+DL P +V
Sbjct: 178 WRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTGELG-LALVLVLNKVDLAPPALVV 236
Query: 185 KWLDYLRNELP 195
W Y P
Sbjct: 237 AWKHYFHQHYP 247
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 40.4 bits (93), Expect = 0.005
Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 55 REAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQ 114
RE E ++K EE EKQ E+E++K++ E ++V ++E FE KEE++ E
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKK-EKKKEEVQEKEEVFEEKEEIMSEEETESL 2321
Query: 115 LDDE 118
D+E
Sbjct: 2322 SDEE 2325
Score = 37.7 bits (86), Expect = 0.029
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 20 KISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQER 79
K W + AK+ G K K S V +H + E E ++E+ +++ + E+E
Sbjct: 2194 KRRWRKRKEAKR-GDKPKEKFSSQVDEVESEEHFSEEME---SLLDELEKQESLSSEEEE 2249
Query: 80 QKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVIL 139
++ E ++V R+EE E KEE E + ++E +K K+ +V E +V
Sbjct: 2250 EREEEEEREEEEV--REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE 2307
Query: 140 E 140
E
Sbjct: 2308 E 2308
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 40.4 bits (93), Expect = 0.005
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 11/100 (11%)
Query: 8 NKKPGEGSKGHKKISWPYPQPAKQNG----KKATSKVPSAPHFVHPNDHANREAELKKKW 63
+KK E G KK P QP KKA + + P F+ A REAE K+
Sbjct: 124 SKKDEEDEHGDKK---PKAQPLSLEELLAKKKAEEEAEAKPKFL---SKAEREAEALKRR 177
Query: 64 VEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKE 103
+E+ E+Q+ E+ER+KR+ + + +L +E E +E
Sbjct: 178 QQEVEERQRML-EEERKKRKQFQDLGRKMLEDPQERERRE 216
Score = 32.0 bits (71), Expect = 1.6
Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 12/135 (8%)
Query: 3 KLRHKNKKPGEGSK-GHKKIS-WPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELK 60
K R +NKK + K GH++ + GK S+ ++H +++ + +
Sbjct: 81 KERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQ 140
Query: 61 KKWVEEMREKQQAAREQERQKR--RTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDE 118
+EE+ K++A E E + + E + + RRQ+E E ++ +L+E +
Sbjct: 141 PLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEE--------ER 192
Query: 119 ATRKAYYKEFRKVVE 133
RK + RK++E
Sbjct: 193 KKRKQFQDLGRKMLE 207
>gi|111955139 GTP-binding protein 10 isoform 2 [Homo sapiens]
Length = 387
Score = 40.0 bits (92), Expect = 0.006
Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 25/142 (17%)
Query: 255 VGVVGLPNVGKSSLINSLKRSRACSVGAV-----PGITKFMQEVYLDKFIRLLDAPGIVP 309
VG+VG PN GKSSL++ + ++ P + K M + K I + D PG++
Sbjct: 151 VGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDF--KQISVADLPGLIE 208
Query: 310 GPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEH--FLTAVA 367
G + G + H+++ + V+ +SGFQ + H + TA
Sbjct: 209 GAHMNKGMGHKFLKHIERTRQLLFVVD----------------ISGFQLSSHTQYRTAFE 252
Query: 368 HRLGKKKKGGLYSQEQAAKAVL 389
+ K+ LY +E K L
Sbjct: 253 TIILLTKELELYKEELQTKPAL 274
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 39.3 bits (90), Expect = 0.010
Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 11/64 (17%)
Query: 55 REAELKKKWVEEMREKQQAAREQ-----------ERQKRRTIESYCQDVLRRQEEFEHKE 103
RE +L++K EE RE+Q+ REQ E+Q RR E + LRR++E E +E
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 104 EVLQ 107
+ L+
Sbjct: 362 QQLR 365
Score = 37.7 bits (86), Expect = 0.029
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 9/149 (6%)
Query: 54 NREAELKKKWV---EEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELN 110
++E E +++W+ EE R +QQ REQ Q RR E + L+RQEE E ++ L+
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQ--QLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 111 MFPQLDDEATRKAYYKEFRKVVEY----SDVILEVLDARDPLGCRCFQMEEAVLRAQGNK 166
+ +E + +E K +E + E + RD L R + + L+ + +
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 167 KLVLVLNKIDLVPKEVVEKWLDYLRNELP 195
+L L + ++ E E+ L+ E P
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEP 625
Score = 35.8 bits (81), Expect = 0.11
Identities = 32/119 (26%), Positives = 48/119 (40%), Gaps = 8/119 (6%)
Query: 45 HFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEE 104
HF E + K+ + +E++Q RE+ +KRR E+ +F +E+
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET--------DRKFREEEQ 1343
Query: 105 VLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQ 163
+LQE P E RK +E R + + E R R F EE LR Q
Sbjct: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/89 (25%), Positives = 48/89 (53%), Gaps = 9/89 (10%)
Query: 51 DHANREAELKKKWVEEMREKQ-----QAAREQ----ERQKRRTIESYCQDVLRRQEEFEH 101
+ RE +L+++ EE RE+Q Q REQ E+Q RR + + LRR+++
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 102 KEEVLQELNMFPQLDDEATRKAYYKEFRK 130
++++ +E + + ++E + + +E R+
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERRE 444
Score = 33.5 bits (75), Expect = 0.55
Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 55 REAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVL---QELNM 111
RE + +++ + +R +QQ R+QE ++R E + RR+++ E +E+ L QE
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
Query: 112 FPQLDDEATRKAYYKEFRKVVE 133
QL E + ++ R+ E
Sbjct: 348 EQQLRREQEEERREQQLRREQE 369
Score = 33.5 bits (75), Expect = 0.55
Identities = 24/67 (35%), Positives = 38/67 (56%), Gaps = 12/67 (17%)
Query: 55 REAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVL---QELNM 111
RE +L+++ +E R +QQ REQE ++R + LRR++E E +E+ L Q+L
Sbjct: 335 REQQLRRE--QEERREQQLRREQEEERR-------EQQLRREQEEERREQQLRREQQLRR 385
Query: 112 FPQLDDE 118
QL E
Sbjct: 386 EQQLRRE 392
Score = 32.7 bits (73), Expect = 0.94
Identities = 19/54 (35%), Positives = 35/54 (64%), Gaps = 2/54 (3%)
Query: 55 REAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQE 108
RE +L+++ EE RE QQ REQE ++RR + + LRR+++ ++++ +E
Sbjct: 347 REQQLRREQEEERRE-QQLRREQE-EERREQQLRREQQLRREQQLRREQQLRRE 398
Score = 32.7 bits (73), Expect = 0.94
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 55 REAELKKKWVEEMREKQQAAREQ-----ERQKRRTIESYCQDVLRRQEEFEHKEEVLQE 108
R +L K +E R +QQ REQ +R KR E + L+R+ E E +E+ L E
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Score = 32.7 bits (73), Expect = 0.94
Identities = 24/92 (26%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 49 PNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEE-VLQ 107
P +E E K + EE++++++ +ER+KRR E Q R+++E + +EE +L+
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ--YRKKDELQQEEEQLLR 1035
Query: 108 ELNMFPQLDDEATRKAYYKEFRKVVEYSDVIL 139
E +L + R+ Y+E ++ + + +L
Sbjct: 1036 EEREKRRLQE---RERQYREEEELQQEEEQLL 1064
Score = 32.0 bits (71), Expect = 1.6
Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
Query: 49 PNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQE 108
P +E E + + EE++++++ +ER+KRR E Q R +EE + +EE L
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ--YREEEEVQQEEEQLLR 1155
Query: 109 LNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKK 167
+ E R+ Y +E E ++ E + R R ++ EE + R + ++
Sbjct: 1156 EEPEKRRRQELERQ-YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Score = 30.8 bits (68), Expect = 3.6
Identities = 23/92 (25%), Positives = 48/92 (52%), Gaps = 11/92 (11%)
Query: 48 HPNDHANREAELKKKWVEEMREKQQAAREQERQKR--RTIES-------YCQDVLRRQEE 98
H + E +L+++ + E+R K + ++Q+R++R R + + VLR++EE
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 99 FEHKEEVLQELNMFPQLDDEATRKAYYKEFRK 130
+EE ++ + Q ++E RK +E R+
Sbjct: 259 KLQEEEPQRQREL--QEEEEQLRKLERQELRR 288
Score = 30.8 bits (68), Expect = 3.6
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Query: 55 REAELKKKWVEEMRE-KQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEE 104
RE +L+++ EE E K + R ++R KR E +D L+R+EE E E+
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEER--RDWLKREEETERHEQ 469
Score = 30.4 bits (67), Expect = 4.7
Identities = 21/85 (24%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 55 REAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQ 114
+E E + + E+++++++ +ER+KRR E Q R+ ++ + KEE Q L P+
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ--YRKDKKLQQKEE--QLLGEEPE 979
Query: 115 LDDEATRKAYYKEFRKVVEYSDVIL 139
R+ Y+E ++ + + +L
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLL 1004
Score = 30.4 bits (67), Expect = 4.7
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 1/105 (0%)
Query: 66 EMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYY 125
+ RE++Q R QER+ R+ +E Q R +F +E++LQE E RK
Sbjct: 1431 KFREEEQQVRRQERE-RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 126 KEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVL 170
+E + + D + R R F EE L Q ++ L
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
Score = 29.6 bits (65), Expect = 8.0
Identities = 13/58 (22%), Positives = 33/58 (56%)
Query: 51 DHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQE 108
+ R + +++ +++R +Q+ REQ+ ++ + E Q + R QEE ++++ +E
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Score = 29.6 bits (65), Expect = 8.0
Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 55 REAELKKKWV---------EEMREKQQAAREQERQKRR-----TIESYCQDVLRRQEEFE 100
RE E ++ W+ E+ R KQQ R+QE ++R E + RR+++
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Query: 101 HKEEVLQELNMFPQLDDEATRKAYYKE 127
++E +E + Q ++E ++ E
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSE 535
>gi|193082988 GTP binding protein 3 (mitochondrial) isoform IV [Homo
sapiens]
Length = 524
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 215 VPVDQASESLLKSKACFGAENLMRVLGNYCRLGE----VRTHIRVGVVGLPNVGKSSLIN 270
+P S LL A L LG + R +R+ + V V G PN GKSSL+N
Sbjct: 240 LPSLSLSACLLSPTADIEVRALQVALGAHLRDARRGQRLRSGVHVVVTGPPNAGKSSLVN 299
Query: 271 SLKRSRACSVGAVPGITKFMQEVYLD 296
L R V PG T+ + E +D
Sbjct: 300 LLSRKPVSIVSPEPGTTRDVLETPVD 325
Score = 34.3 bits (77), Expect = 0.32
Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 12/74 (16%)
Query: 115 LDDEATRKAYYKEFRKVVEYSDVILEVLDARD---PLGCRCFQMEEAVLRAQG----NKK 167
++ E R+A R+ +E +D+IL +LDA D P C A + AQ +++
Sbjct: 346 VEQEGVRRA-----RERLEQADLILAMLDASDLASPSSCNFLATVVASVGAQSPSDSSQR 400
Query: 168 LVLVLNKIDLVPKE 181
L+LVLNK DL+ E
Sbjct: 401 LLLVLNKSDLLSPE 414
>gi|4758796 developmentally regulated GTP binding protein 1 [Homo
sapiens]
Length = 367
Score = 39.3 bits (90), Expect = 0.010
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 18/95 (18%)
Query: 254 RVGVVGLPNVGKSSLINSL-------KRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPG 306
R+G VG P+VGKS+L+++L ++ VPG+ + Y I+LLD PG
Sbjct: 66 RIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIR-----YKGAKIQLLDLPG 120
Query: 307 IVPGPNS------EVGTILRNCVHVQKLADPVTPV 335
I+ G +V + R C + + D + P+
Sbjct: 121 IIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPL 155
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 38.9 bits (89), Expect = 0.013
Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 3/82 (3%)
Query: 56 EAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQL 115
+AE K +++++K++ REQ ++R E +++LR Q+ E KE LQEL + +
Sbjct: 314 QAEGKTSLHKDLKQKRREQREQRERRRAAKE---EELLRLQQLQEEKERKLQELELLQEA 370
Query: 116 DDEATRKAYYKEFRKVVEYSDV 137
+A R +E R+ ++ ++
Sbjct: 371 QRQAERLLQEEEERRRSQHREL 392
>gi|58761500 Obg-like ATPase 1 isoform 1 [Homo sapiens]
Length = 396
Score = 38.9 bits (89), Expect = 0.013
Identities = 32/141 (22%), Positives = 57/141 (40%), Gaps = 40/141 (28%)
Query: 246 LGEVRTHIRVGVVGLPNVGKSSLINSLKRSRA-------CSVGAVPGITKFMQEVY---- 294
+G T +++G+VGLPNVGKS+ N L S+A C++ E +
Sbjct: 16 IGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLC 75
Query: 295 --------LDKFIRLLDAPGIVPGPNSEVG------TILRNC---------------VHV 325
+ F+ ++D G+V G ++ G + + C HV
Sbjct: 76 QYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISACDGIFHLTRAFEDDDITHV 135
Query: 326 QKLADPVTPVETILQRCNLEE 346
+ DP+ +E I + L++
Sbjct: 136 EGSVDPIRDIEIIHEELQLKD 156
>gi|193082993 GTP binding protein 3 (mitochondrial) isoform III
[Homo sapiens]
Length = 471
Score = 38.5 bits (88), Expect = 0.017
Identities = 20/48 (41%), Positives = 27/48 (56%)
Query: 249 VRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLD 296
+R+ + V V G PN GKSSL+N L R V PG T+ + E +D
Sbjct: 246 LRSGVHVVVTGPPNAGKSSLVNLLSRKPVSIVSPEPGTTRDVLETPVD 293
>gi|193082991 GTP binding protein 3 (mitochondrial) isoform V [Homo
sapiens]
Length = 492
Score = 38.5 bits (88), Expect = 0.017
Identities = 20/48 (41%), Positives = 27/48 (56%)
Query: 249 VRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLD 296
+R+ + V V G PN GKSSL+N L R V PG T+ + E +D
Sbjct: 246 LRSGVHVVVTGPPNAGKSSLVNLLSRKPVSIVSPEPGTTRDVLETPVD 293
Score = 34.3 bits (77), Expect = 0.32
Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 12/74 (16%)
Query: 115 LDDEATRKAYYKEFRKVVEYSDVILEVLDARD---PLGCRCFQMEEAVLRAQG----NKK 167
++ E R+A R+ +E +D+IL +LDA D P C A + AQ +++
Sbjct: 314 VEQEGVRRA-----RERLEQADLILAMLDASDLASPSSCNFLATVVASVGAQSPSDSSQR 368
Query: 168 LVLVLNKIDLVPKE 181
L+LVLNK DL+ E
Sbjct: 369 LLLVLNKSDLLSPE 382
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 38.1 bits (87), Expect = 0.022
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 29/248 (11%)
Query: 24 PYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKK-KWVE----EMREKQQAAREQE 78
P P P G + + +P P + P E +++ W++ EM E + E
Sbjct: 348 PPPPPLGFLGGQNSPPLPILPFGLKPKKEFKPEISMRRLNWLKIRPHEMTENCFWIKVNE 407
Query: 79 RQKRRTIESYC---------QDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKA--YYKE 127
K ++ C Q R +E+ E K+ + +++ LD + + +
Sbjct: 408 N-KYENVDLLCKLENTFCCQQKERREEEDIEEKKSIKKKIKELKFLDSKIAQNLSIFLSS 466
Query: 128 FRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKI-----DLVPKE- 181
FR V Y ++ + +L+ + M + +++ +++ + L++ +L E
Sbjct: 467 FR--VPYEEIRMMILEVDETRLAE--SMIQNLIKHLPDQEQLNSLSQFKSEYSNLCEPEQ 522
Query: 182 --VVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRV 239
VV + LR L + FK + QV N+ + V A E + KSK+ L+ +
Sbjct: 523 FVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLL 582
Query: 240 LGNYCRLG 247
+GNY G
Sbjct: 583 MGNYMNAG 590
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 38.1 bits (87), Expect = 0.022
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 29/248 (11%)
Query: 24 PYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKK-KWVE----EMREKQQAAREQE 78
P P P G + + +P P + P E +++ W++ EM E + E
Sbjct: 611 PPPPPLGFLGGQNSPPLPILPFGLKPKKEFKPEISMRRLNWLKIRPHEMTENCFWIKVNE 670
Query: 79 RQKRRTIESYC---------QDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKA--YYKE 127
K ++ C Q R +E+ E K+ + +++ LD + + +
Sbjct: 671 N-KYENVDLLCKLENTFCCQQKERREEEDIEEKKSIKKKIKELKFLDSKIAQNLSIFLSS 729
Query: 128 FRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKI-----DLVPKE- 181
FR V Y ++ + +L+ + M + +++ +++ + L++ +L E
Sbjct: 730 FR--VPYEEIRMMILEVDETRLAE--SMIQNLIKHLPDQEQLNSLSQFKSEYSNLCEPEQ 785
Query: 182 --VVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRV 239
VV + LR L + FK + QV N+ + V A E + KSK+ L+ +
Sbjct: 786 FVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLL 845
Query: 240 LGNYCRLG 247
+GNY G
Sbjct: 846 MGNYMNAG 853
>gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]
Length = 390
Score = 37.7 bits (86), Expect = 0.029
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 11/91 (12%)
Query: 26 PQPAKQNGKKATSKVPSAPH--FVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRR 83
P K + +KA +K + H + H+ R AE W + EK E +
Sbjct: 219 PNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQES 278
Query: 84 TIESYCQDVLRRQEEFEHKEEVLQELNMFPQ 114
T RR+++++ +E L E+N FPQ
Sbjct: 279 T---------RRRQKYQESQEPLNEVNSFPQ 300
>gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]
Length = 485
Score = 37.7 bits (86), Expect = 0.029
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 11/91 (12%)
Query: 26 PQPAKQNGKKATSKVPSAPH--FVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRR 83
P K + +KA +K + H + H+ R AE W + EK E +
Sbjct: 314 PNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQES 373
Query: 84 TIESYCQDVLRRQEEFEHKEEVLQELNMFPQ 114
T RR+++++ +E L E+N FPQ
Sbjct: 374 T---------RRRQKYQESQEPLNEVNSFPQ 395
>gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 37.7 bits (86), Expect = 0.029
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 11/91 (12%)
Query: 26 PQPAKQNGKKATSKVPSAPH--FVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRR 83
P K + +KA +K + H + H+ R AE W + EK E +
Sbjct: 337 PNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQES 396
Query: 84 TIESYCQDVLRRQEEFEHKEEVLQELNMFPQ 114
T RR+++++ +E L E+N FPQ
Sbjct: 397 T---------RRRQKYQESQEPLNEVNSFPQ 418
>gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 37.7 bits (86), Expect = 0.029
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 11/91 (12%)
Query: 26 PQPAKQNGKKATSKVPSAPH--FVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRR 83
P K + +KA +K + H + H+ R AE W + EK E +
Sbjct: 337 PNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQES 396
Query: 84 TIESYCQDVLRRQEEFEHKEEVLQELNMFPQ 114
T RR+++++ +E L E+N FPQ
Sbjct: 397 T---------RRRQKYQESQEPLNEVNSFPQ 418
>gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 37.7 bits (86), Expect = 0.029
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 11/91 (12%)
Query: 26 PQPAKQNGKKATSKVPSAPH--FVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRR 83
P K + +KA +K + H + H+ R AE W + EK E +
Sbjct: 337 PNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQES 396
Query: 84 TIESYCQDVLRRQEEFEHKEEVLQELNMFPQ 114
T RR+++++ +E L E+N FPQ
Sbjct: 397 T---------RRRQKYQESQEPLNEVNSFPQ 418
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 37.4 bits (85), Expect = 0.038
Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 16/129 (12%)
Query: 52 HANREAELKKKWVEEMREKQQAAREQERQKRRTI----ESYCQDVLRRQEEFEHKEEVLQ 107
H+ + A+ + + + + REK QAA+E+ R++R + E QD R + E E L+
Sbjct: 610 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLE 669
Query: 108 ELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQ-GNK 166
+L E R KE +VE + + RD L ++ EA+ +A+ G
Sbjct: 670 QL--------EGKRSVLAKE---LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRV 718
Query: 167 KLVLVLNKI 175
+L L + K+
Sbjct: 719 ELELSMTKL 727
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 37.4 bits (85), Expect = 0.038
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 2/107 (1%)
Query: 27 QPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIE 86
Q K+ ++ K A + RE E +++ E ++Q REQERQ
Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 724
Query: 87 SYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVE 133
Q+ L+ + E + +E+ L+ QL E K +E +++ E
Sbjct: 725 RREQERLQAERELQEREKALRLQK--EQLQRELEEKKKKEEQQRLAE 769
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 37.4 bits (85), Expect = 0.038
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 2/107 (1%)
Query: 27 QPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIE 86
Q K+ ++ K A + RE E +++ E ++Q REQERQ
Sbjct: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 720
Query: 87 SYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVE 133
Q+ L+ + E + +E+ L+ QL E K +E +++ E
Sbjct: 721 RREQERLQAERELQEREKALRLQK--EQLQRELEEKKKKEEQQRLAE 765
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 37.0 bits (84), Expect = 0.050
Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 14/119 (11%)
Query: 32 NGKKATSKVPSAPHFVHPNDHAN--REAELKK---KWVEEMREKQQAAREQERQKRRTIE 86
+ K+ V +A H A+ EL+K + EE++ K Q R E +K I
Sbjct: 371 DAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 430
Query: 87 SYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDAR 145
+ Q++ HKE++LQE Q D + K +E ++++LE L R
Sbjct: 431 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSD---------KTLEANEMLLEKLRQR 480
>gi|50658071 phosphodiesterase 4D interacting protein isoform 5
[Homo sapiens]
Length = 1132
Score = 37.0 bits (84), Expect = 0.050
Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 14/119 (11%)
Query: 32 NGKKATSKVPSAPHFVHPNDHAN--REAELKK---KWVEEMREKQQAAREQERQKRRTIE 86
+ K+ V +A H A+ EL+K + EE++ K Q R E +K I
Sbjct: 534 DAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 593
Query: 87 SYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDAR 145
+ Q++ HKE++LQE Q D + K +E ++++LE L R
Sbjct: 594 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSD---------KTLEANEMLLEKLRQR 643
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,224,705
Number of Sequences: 37866
Number of extensions: 1000159
Number of successful extensions: 6960
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 195
Number of HSP's that attempted gapping in prelim test: 5299
Number of HSP's gapped (non-prelim): 1412
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.