Guide to the Human Genome
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Search of human proteins with 9506557

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9506557 Down syndrome critical region protein 6 [Homo
sapiens]
         (190 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9506557 Down syndrome critical region protein 6 [Homo sapiens]     409   e-115
gi|156523052 ripply1 homolog [Homo sapiens]                            67   9e-12
gi|58000465 ripply2 protein [Homo sapiens]                             65   3e-11
gi|78499633 phospholipase C, eta 2 [Homo sapiens]                      38   0.005
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    38   0.006
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    38   0.006
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      38   0.006
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      38   0.006
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]       38   0.006
gi|239745779 PREDICTED: hypothetical protein XP_002343588 [Homo ...    37   0.010
gi|29570782 additional sex combs like 1 [Homo sapiens]                 37   0.013
gi|71043876 undifferentiated embryonic cell transcription factor...    36   0.017
gi|239751485 PREDICTED: hypothetical protein isoform 2 [Homo sap...    36   0.023
gi|239751483 PREDICTED: hypothetical protein isoform 1 [Homo sap...    36   0.023
gi|189571667 zinc finger protein 696 [Homo sapiens]                    36   0.023
gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom...    35   0.030
gi|188536004 zinc finger protein 469 [Homo sapiens]                    35   0.039
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     35   0.039
gi|22035569 GC-rich sequence DNA-binding factor candidate isofor...    35   0.051
gi|22035565 GC-rich sequence DNA-binding factor candidate isofor...    35   0.051
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ...    35   0.051
gi|40254439 endothelial PAS domain protein 1 [Homo sapiens]            33   0.11 
gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]    33   0.11 
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               33   0.11 
gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]            33   0.15 
gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]            33   0.15 
gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo ...    33   0.15 
gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]            33   0.15 
gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo ...    33   0.15 
gi|55741677 SET domain containing 1A [Homo sapiens]                    33   0.15 

>gi|9506557 Down syndrome critical region protein 6 [Homo sapiens]
          Length = 190

 Score =  409 bits (1052), Expect = e-115
 Identities = 190/190 (100%), Positives = 190/190 (100%)

Query: 1   MEPEAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEP 60
           MEPEAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEP
Sbjct: 1   MEPEAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEP 60

Query: 61  RADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDESTESA 120
           RADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDESTESA
Sbjct: 61  RADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDESTESA 120

Query: 121 SEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVS 180
           SEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVS
Sbjct: 121 SEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVS 180

Query: 181 SRGGKCSSSK 190
           SRGGKCSSSK
Sbjct: 181 SRGGKCSSSK 190


>gi|156523052 ripply1 homolog [Homo sapiens]
          Length = 151

 Score = 67.0 bits (162), Expect = 9e-12
 Identities = 36/96 (37%), Positives = 52/96 (54%), Gaps = 11/96 (11%)

Query: 39  WRPWIQTPGDAELTRTGRPLEPRADQHTFGS------KGAFGFQHPVRVYLPMSKRQEYL 92
           WRPW+ +  D+      R +    D    G+      K    F HPVR++ P S+  +YL
Sbjct: 57  WRPWLSSTNDSP-----RQMRKLVDLAAGGATAAEVTKAESKFHHPVRLFWPKSRSFDYL 111

Query: 93  RSSGEQVLASFPVQATIDFYDDESTESASEAEEPEE 128
            S+GE +L +FPVQATI+ Y+D  +E   E EE E+
Sbjct: 112 YSAGEILLQNFPVQATINLYEDSDSEEEEEDEEQED 147


>gi|58000465 ripply2 protein [Homo sapiens]
          Length = 128

 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 33/86 (38%), Positives = 44/86 (51%), Gaps = 2/86 (2%)

Query: 39  WRPWIQTPGDAELTRTGRPLE--PRADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSG 96
           WRPW+   G  E        E  P     T  S   + F+HPVR++ P SK  +YL    
Sbjct: 37  WRPWVDAGGKKEEETPNHAAEAMPDGPGMTAASGKLYQFRHPVRLFWPKSKCYDYLYQEA 96

Query: 97  EQVLASFPVQATIDFYDDESTESASE 122
           E +L +FP+QATI FY+D  +E   E
Sbjct: 97  EALLKNFPIQATISFYEDSDSEDEIE 122


>gi|78499633 phospholipase C, eta 2 [Homo sapiens]
          Length = 1416

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 45/159 (28%), Positives = 57/159 (35%), Gaps = 28/159 (17%)

Query: 3    PEAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRA 62
            PE   G R    +G     D    P P   PE+PA   P   +P D     T RPL P  
Sbjct: 945  PELVLGTRDTGSKGV---ADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLPPLC 1001

Query: 63   DQHTFGSKGAFGFQHPVRVYLPMSK---RQEYLRSSGEQVLASFPVQATIDFYDDESTES 119
               T   + A G   P    +P S    R  Y    G  V +  P++ T           
Sbjct: 1002 SLETIAEEPAPGPGPPPPAAVPTSSSQGRPPYPTGPGANVAS--PLEDT----------- 1048

Query: 120  ASEAEEPEEG-PPPLHLLPQEVGGRQENGPGGK--GRDQ 155
                EEP +  P P +   +  GG  E  PG +  GR Q
Sbjct: 1049 ----EEPRDSRPRPCN--GEGAGGAYERAPGSQTDGRSQ 1081


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 37.7 bits (86), Expect = 0.006
 Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 41/181 (22%)

Query: 20  PGDAPWRP---PPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQ 76
           PG  P +P   PP   P S +  +P            T       + Q+T+G   ++G Q
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYSSTQP------------TSYDQSSYSQQNTYGQPSSYGQQ 223

Query: 77  HPVRVYLPMSKRQEYLRSSGEQVLASFPVQA-----TIDFYDDESTESASEAEEPEEGPP 131
                    S  Q+   S G+Q   S+P Q          Y  +S+    ++   ++ P 
Sbjct: 224 S--------SYGQQ--SSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 273

Query: 132 PLHLLPQEVGG-------RQENGPGGKGRDQ-GINQGQRSSGGGDHWGEGPLPQGVSSRG 183
            + +  QE GG       R  +GP  +GR + G ++G  S GG    G G    G   RG
Sbjct: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGR---GGGRGGMGAGERG 330

Query: 184 G 184
           G
Sbjct: 331 G 331


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 37.7 bits (86), Expect = 0.006
 Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 41/181 (22%)

Query: 20  PGDAPWRP---PPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQ 76
           PG  P +P   PP   P S +  +P            T       + Q+T+G   ++G Q
Sbjct: 182 PGSYPMQPVTAPPSYPPTSYSSTQP------------TSYDQSSYSQQNTYGQPSSYGQQ 229

Query: 77  HPVRVYLPMSKRQEYLRSSGEQVLASFPVQA-----TIDFYDDESTESASEAEEPEEGPP 131
                    S  Q+   S G+Q   S+P Q          Y  +S+    ++   ++ P 
Sbjct: 230 S--------SYGQQ--SSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 279

Query: 132 PLHLLPQEVGG-------RQENGPGGKGRDQ-GINQGQRSSGGGDHWGEGPLPQGVSSRG 183
            + +  QE GG       R  +GP  +GR + G ++G  S GG    G G    G   RG
Sbjct: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGR---GGGRGGMGAGERG 336

Query: 184 G 184
           G
Sbjct: 337 G 337


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 37.7 bits (86), Expect = 0.006
 Identities = 40/149 (26%), Positives = 53/149 (35%), Gaps = 18/149 (12%)

Query: 27  PPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMS 86
           P PP    SP P  P  QTP         RP+EP+   H    K     + P++ Y    
Sbjct: 547 PEPPIPQASPGPPGPLSQTP------PMQRPVEPQEGPH----KSLVAHRVPLKPYAAPV 596

Query: 87  KRQEYLRSSGEQVLASFPVQATIDFYDDESTESAS--------EAEEPEEGPPPLHLLPQ 138
            R + L+    + LA+FP     D      T + S         ++   EGP P    P 
Sbjct: 597 PRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPA 656

Query: 139 EVGGRQENGPGGKGRDQGINQGQRSSGGG 167
            V    E  P    R   I     +SG G
Sbjct: 657 WVRPDNEAPPKVPQRTSSIATALNTSGAG 685


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 37.7 bits (86), Expect = 0.006
 Identities = 40/149 (26%), Positives = 53/149 (35%), Gaps = 18/149 (12%)

Query: 27  PPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMS 86
           P PP    SP P  P  QTP         RP+EP+   H    K     + P++ Y    
Sbjct: 547 PEPPIPQASPGPPGPLSQTP------PMQRPVEPQEGPH----KSLVAHRVPLKPYAAPV 596

Query: 87  KRQEYLRSSGEQVLASFPVQATIDFYDDESTESAS--------EAEEPEEGPPPLHLLPQ 138
            R + L+    + LA+FP     D      T + S         ++   EGP P    P 
Sbjct: 597 PRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPA 656

Query: 139 EVGGRQENGPGGKGRDQGINQGQRSSGGG 167
            V    E  P    R   I     +SG G
Sbjct: 657 WVRPDNEAPPKVPQRTSSIATALNTSGAG 685


>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
          Length = 1295

 Score = 37.7 bits (86), Expect = 0.006
 Identities = 40/149 (26%), Positives = 53/149 (35%), Gaps = 18/149 (12%)

Query: 27  PPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMS 86
           P PP    SP P  P  QTP         RP+EP+   H    K     + P++ Y    
Sbjct: 547 PEPPIPQASPGPPGPLSQTP------PMQRPVEPQEGPH----KSLVAHRVPLKPYAAPV 596

Query: 87  KRQEYLRSSGEQVLASFPVQATIDFYDDESTESAS--------EAEEPEEGPPPLHLLPQ 138
            R + L+    + LA+FP     D      T + S         ++   EGP P    P 
Sbjct: 597 PRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPA 656

Query: 139 EVGGRQENGPGGKGRDQGINQGQRSSGGG 167
            V    E  P    R   I     +SG G
Sbjct: 657 WVRPDNEAPPKVPQRTSSIATALNTSGAG 685


>gi|239745779 PREDICTED: hypothetical protein XP_002343588 [Homo
           sapiens]
          Length = 201

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 27/96 (28%), Positives = 36/96 (37%), Gaps = 15/96 (15%)

Query: 16  GCHCPGDAPWRPPPP-RGP------ESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFG 68
           G H P    W PP    GP      +  A W  W   PG+    R  RP E  A+Q   G
Sbjct: 2   GTHRPQQVEWFPPAKGEGPMMGYSRDVEADWAGWTVPPGNTRGKRRARPQEDHAEQEIPG 61

Query: 69  SKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFP 104
              +           P++ R++ L S+    L  FP
Sbjct: 62  ENPS--------ARTPLNTREDSLPSASPPGLLHFP 89


>gi|29570782 additional sex combs like 1 [Homo sapiens]
          Length = 1541

 Score = 36.6 bits (83), Expect = 0.013
 Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 141 GGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVSSRGGKCSS 188
           GG    G GG   D+G  +G  S  GG+  G  P P+G  S  GKC+S
Sbjct: 643 GGGGPGGGGGGATDEGGGRGSSSGDGGEACGH-PEPRGGPSTPGKCTS 689


>gi|71043876 undifferentiated embryonic cell transcription factor
          1 [Homo sapiens]
          Length = 341

 Score = 36.2 bits (82), Expect = 0.017
 Identities = 21/41 (51%), Positives = 22/41 (53%), Gaps = 2/41 (4%)

Query: 24 PWRPPP--PRGPESPAPWRPWIQTPGDAELTRTGRPLEPRA 62
          P RPPP  P  P SPA   P  +TPGDA  T   RP  P A
Sbjct: 5  PRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSA 45


>gi|239751485 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 122

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 13/73 (17%)

Query: 2   EPEAAAGARKARGR---GCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPL 58
           +P  A G R AR     G H     P  PPPP  P   APWR W Q P         +PL
Sbjct: 53  DPRVAEGLRDARPAPEGGVHLTPQ-PEPPPPPPSPACAAPWR-WGQEP--------SQPL 102

Query: 59  EPRADQHTFGSKG 71
            PR      G +G
Sbjct: 103 SPRPYLGPRGCRG 115


>gi|239751483 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 122

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 13/73 (17%)

Query: 2   EPEAAAGARKARGR---GCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPL 58
           +P  A G R AR     G H     P  PPPP  P   APWR W Q P         +PL
Sbjct: 53  DPRVAEGLRDARPAPEGGVHLTPQ-PEPPPPPPSPACAAPWR-WGQEP--------SQPL 102

Query: 59  EPRADQHTFGSKG 71
            PR      G +G
Sbjct: 103 SPRPYLGPRGCRG 115


>gi|189571667 zinc finger protein 696 [Homo sapiens]
          Length = 374

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 41/130 (31%), Positives = 49/130 (37%), Gaps = 28/130 (21%)

Query: 86  SKRQEYLRSSGEQVLASFPVQA-----TIDFYDDESTESASEAEEPE----EGPPPLHLL 136
           +K    L  S   V A+F  QA     + +    +STE A+EA  PE     G PP  L 
Sbjct: 10  AKESSTLMESLAAVKAAFLAQAPSGSRSAEVQAAQSTEPAAEAGAPEGEGHRGGPPRALG 69

Query: 137 PQEVGGRQE--NGPGGKGR----------------DQGINQGQRSSGGGDHWGEGPLPQG 178
              +   QE    PGG  R                D   N G  + GGG  W   P P G
Sbjct: 70  SLGLCENQEARERPGGSPRGPVTSEKTGGQSGLESDVPPNAGPGAEGGGS-WKGRPFPCG 128

Query: 179 VSSRGGKCSS 188
              R  KCSS
Sbjct: 129 ACGRSFKCSS 138


>gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo
           sapiens]
          Length = 2063

 Score = 35.4 bits (80), Expect = 0.030
 Identities = 48/172 (27%), Positives = 64/172 (37%), Gaps = 40/172 (23%)

Query: 16  GCHCPGDAPWRPPP--PRGPESPAPWRPWIQTPGDAELTRTGRPLE-PRAD--------Q 64
           G   P  A W PP    R P +P P R      G     R+ RPL  P  +        Q
Sbjct: 149 GTPSPDGAAWEPPARESRQPPTPPP-RTCFPLAG----LRSARPLTGPETEGRLRRPQQQ 203

Query: 65  HTFGSKGAFGFQHPVRVYLPMSKRQEYLRSS--GEQVLASFPVQATIDFYDDESTESASE 122
                + A G  H   ++   S+ Q   R+S     + AS+PV  +          +AS 
Sbjct: 204 QERAQRPADGL-HSWHIF---SQPQAGARASCSSSSIAASYPVSRS---------RAASS 250

Query: 123 AEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGP 174
           +EE EEGPP       ++ G Q   P   G     +   R   GG  WG  P
Sbjct: 251 SEEEEEGPP-------QLPGAQ--SPAYHGGHSSGSDDDRDGEGGHRWGGRP 293


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 35.0 bits (79), Expect = 0.039
 Identities = 48/166 (28%), Positives = 69/166 (41%), Gaps = 46/166 (27%)

Query: 6    AAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWR---PWIQTPGDAEL---TRTGRP-- 57
            A+G R  R  G    G+ P  PP PR P + AP     P  + P  A L   TR+ R   
Sbjct: 975  ASGLRPRRNDGL---GERP--PPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRR 1029

Query: 58   LEPRADQHTFGSKG-AFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDES 116
            L PR D     ++G A+G +  +++    ++ +EY                  DF     
Sbjct: 1030 LPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY------------------DF----- 1066

Query: 117  TESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQR 162
               ASE+EE E+ P      P+  G R   G G K ++  + QG R
Sbjct: 1067 ---ASESEEDEQPP------PRGPGFRGRRGRGEKRKEVELTQGPR 1103


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 35.0 bits (79), Expect = 0.039
 Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 40/181 (22%)

Query: 21  GDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVR 80
           G+ P  PPPP  P+ P P        GD   +    P +P+      G++       P  
Sbjct: 86  GNKPQGPPPPGKPQGPPP-------QGDKSRSPRSPPGKPQGPPPQGGNQ-------PQG 131

Query: 81  VYLPMSKRQEYLRSSGEQVLASFP---VQATIDFYDDESTESASEAEEPE---------- 127
              P  K Q      G +     P    Q      D++S  S S   +P+          
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191

Query: 128 EGPPPLHLLPQ---EVGGRQENGPGGKGRDQG-------INQGQRSSGGGDHWGEGPLPQ 177
           +GPPP    PQ     GG +  GP   G+ QG        +Q  RS  G     +GP PQ
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP---QGPPPQ 248

Query: 178 G 178
           G
Sbjct: 249 G 249



 Score = 32.7 bits (73), Expect = 0.19
 Identities = 47/180 (26%), Positives = 63/180 (35%), Gaps = 37/180 (20%)

Query: 21  GDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRT--GRPLEPRADQHTFGSKGAFGFQHP 78
           G+ P  PPPP  P+ P P     Q    +  +R+  G+P  P             G   P
Sbjct: 147 GNKPQGPPPPGKPQGPPP-----QGDNKSRSSRSPPGKPQGPPPQ----------GGNQP 191

Query: 79  VRVYLPMSKRQEYLRSSGEQVLASFPV---QATIDFYDDESTESASEAEEPE-------- 127
                P  K Q      G +     P    Q      D++S  + S   +P+        
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251

Query: 128 --EGPPPLHLLPQ---EVGGRQENGPGGKGRDQGI----NQGQRSSGGGDHWGEGPLPQG 178
             +GPPP    PQ     GG +  GP   G+ QG         RSS       +GP PQG
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQG 311



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 116 STESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGP- 174
           S ++ +E    EE P  +   PQ    +  N P G     G  QG    GG    G  P 
Sbjct: 15  SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPP 74

Query: 175 --LPQGVSSRGG 184
              PQG   +GG
Sbjct: 75  PGKPQGPPPQGG 86



 Score = 27.7 bits (60), Expect = 6.2
 Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 7/70 (10%)

Query: 128 EGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWG-------EGPLPQGVS 180
           +GPP     PQ    +  N P G     G  QG    GG    G       +GP PQG  
Sbjct: 48  QGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 107

Query: 181 SRGGKCSSSK 190
           SR  +    K
Sbjct: 108 SRSPRSPPGK 117


>gi|22035569 GC-rich sequence DNA-binding factor candidate isoform 2
           [Homo sapiens]
          Length = 815

 Score = 34.7 bits (78), Expect = 0.051
 Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 13/70 (18%)

Query: 114 DESTESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEG 173
           ++S E   E +E +E PP   LLP   G  +E GPGG         G R+ GG    G G
Sbjct: 14  NDSEEEERERDEEQEPPP---LLPPP-GTGEEAGPGG---------GDRAPGGESLLGPG 60

Query: 174 PLPQGVSSRG 183
           P P    + G
Sbjct: 61  PSPPSALTPG 70


>gi|22035565 GC-rich sequence DNA-binding factor candidate isoform 1
           [Homo sapiens]
          Length = 917

 Score = 34.7 bits (78), Expect = 0.051
 Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 13/70 (18%)

Query: 114 DESTESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEG 173
           ++S E   E +E +E PP   LLP   G  +E GPGG         G R+ GG    G G
Sbjct: 14  NDSEEEERERDEEQEPPP---LLPPP-GTGEEAGPGG---------GDRAPGGESLLGPG 60

Query: 174 PLPQGVSSRG 183
           P P    + G
Sbjct: 61  PSPPSALTPG 70


>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
           [Homo sapiens]
          Length = 285

 Score = 34.7 bits (78), Expect = 0.051
 Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 137 PQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVSSRGG 184
           P+EV  +Q+ G GG+G     N+G  S GGG   G+G    G S R G
Sbjct: 231 PKEVYQQQQYGSGGRGNRNRGNRG--SGGGGGGGGQGSTNYGKSQRRG 276


>gi|40254439 endothelial PAS domain protein 1 [Homo sapiens]
          Length = 870

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 26/92 (28%), Positives = 35/92 (38%), Gaps = 2/92 (2%)

Query: 29  PPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMSKR 88
           PP G  S   W+      G +      +PL        F      G  HP+R +LP+ + 
Sbjct: 727 PPGGSTSHLMWKRMKNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLR-HLPLPQP 785

Query: 89  QEYLRSSGEQVLASFPVQATIDFYDDESTESA 120
              + S GE   + FP Q     Y D S  SA
Sbjct: 786 PSAI-SPGENSKSRFPPQCYATQYQDYSLSSA 816


>gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]
          Length = 166

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 12/97 (12%)

Query: 92  LRSSGEQVLASFPVQATIDFYDDESTESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGK 151
           L  S  Q L     Q  +     +  +S    +E  +GPP        +GG+Q     G 
Sbjct: 11  LAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPP--------LGGQQSQPSAGD 62

Query: 152 G-RDQGINQGQRSSGGGDHWGEGP---LPQGVSSRGG 184
           G +D G  QG    GG    G  P    PQG   +GG
Sbjct: 63  GNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGG 99


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)

Query: 3   PEAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRPWIQTP-GDAELTRTGRPLEPR 61
           P    G    +G   H  G  P     P+GP+ P    P  Q   G   + R   P  P 
Sbjct: 628 PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPL 687

Query: 62  ADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDESTESAS 121
             Q   G +G+ G Q  +    P    Q ++   G         Q  +       T+   
Sbjct: 688 GPQGPPGPQGSSGPQGHMGPQGPPGP-QGHIGPQGPP-----GPQGHLGPQGPPGTQGMQ 741

Query: 122 EAEEPE--EGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGV 179
               P   +GPP  H +    G +   GP  +G   G+N        G    +GP PQG+
Sbjct: 742 GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGM 801



 Score = 32.0 bits (71), Expect = 0.33
 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 9/52 (17%)

Query: 125 EPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLP 176
           + ++GPP   L P   GG Q  GP G        QGQ++   G H  +GP+P
Sbjct: 859 QSQQGPPQGSLGPPPQGGMQ--GPPGP-------QGQQNPARGPHPSQGPIP 901



 Score = 30.8 bits (68), Expect = 0.73
 Identities = 57/217 (26%), Positives = 73/217 (33%), Gaps = 57/217 (26%)

Query: 4    EAAAGARKARGRGCHCP--GDAPWRPPPPRGPESPAPWRP--WIQT----PGDAELTRTG 55
            E AA  R  RGRG   P  G     P P   P      +P  W       PG      T 
Sbjct: 1140 EEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTP 1199

Query: 56   RPLEPRADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDE 115
            RP  P  D H+  S+                +R   L+      +AS P +    ++D  
Sbjct: 1200 RPDHPPHDGHSPASR----------------ERSSSLQGMD---MASLPPRKR-PWHDGP 1239

Query: 116  STESASEAEEP-----------EEGPPPLHLLPQEVGGRQENGPG----GKGRDQGIN-- 158
             T    E E P             GP P   +P+   GR  +  G    G  RD+     
Sbjct: 1240 GTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKS--GRSSSLDGEHHDGYHRDEPFGGP 1297

Query: 159  --QGQRSSGG--GDHWGEG------PLPQGVSSRGGK 185
               G  S GG  G +WG G      P  +G S  GG+
Sbjct: 1298 PGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGR 1334


>gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 16/30 (53%), Positives = 19/30 (63%), Gaps = 1/30 (3%)

Query: 21 GDAPWRPPPPRGPESP-APWRPWIQTPGDA 49
          G AP + PPP GP +P APWR   + PG A
Sbjct: 32 GRAPPQSPPPAGPGAPGAPWRRGDEGPGPA 61


>gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 16/30 (53%), Positives = 19/30 (63%), Gaps = 1/30 (3%)

Query: 21 GDAPWRPPPPRGPESP-APWRPWIQTPGDA 49
          G AP + PPP GP +P APWR   + PG A
Sbjct: 32 GRAPPQSPPPAGPGAPGAPWRRGDEGPGPA 61


>gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo
          sapiens]
          Length = 408

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 6/39 (15%)

Query: 26 RPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQ 64
          RP  P  P S AP RP  + P      R GRPL PRA Q
Sbjct: 54 RPVSPSAPRSIAPARPGARPP------RPGRPLAPRARQ 86


>gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 16/30 (53%), Positives = 19/30 (63%), Gaps = 1/30 (3%)

Query: 21 GDAPWRPPPPRGPESP-APWRPWIQTPGDA 49
          G AP + PPP GP +P APWR   + PG A
Sbjct: 32 GRAPPQSPPPAGPGAPGAPWRRGDEGPGPA 61


>gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo
          sapiens]
          Length = 408

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 6/39 (15%)

Query: 26 RPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQ 64
          RP  P  P S AP RP  + P      R GRPL PRA Q
Sbjct: 54 RPVSPSAPRSIAPARPGARPP------RPGRPLAPRARQ 86


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 33.1 bits (74), Expect = 0.15
 Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 1/37 (2%)

Query: 3    PEAAAGARKARGRGCHCPGDAPWRPP-PPRGPESPAP 38
            PE  A   +  G     P  AP RPP PP GP +PAP
Sbjct: 1109 PEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAP 1145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.135    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,030,259
Number of Sequences: 37866
Number of extensions: 714415
Number of successful extensions: 5754
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 256
Number of HSP's that attempted gapping in prelim test: 5046
Number of HSP's gapped (non-prelim): 900
length of query: 190
length of database: 18,247,518
effective HSP length: 96
effective length of query: 94
effective length of database: 14,612,382
effective search space: 1373563908
effective search space used: 1373563908
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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