Search of human proteins with 9506363

Search of human proteins with 9506363

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]
         (380 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]             762   0.0  
gi|48762709 SAM domain, SH3 domain and nuclear localization sign...   257   1e-68
gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]            244   1e-64
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    52   9e-07
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap...    50   3e-06
gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo sap...    50   3e-06
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    48   2e-05
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    45   1e-04
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    45   1e-04
gi|41327712 v-crk sarcoma virus CT10 oncogene homolog isoform a ...    42   0.001
gi|11321634 CD2-associated protein [Homo sapiens]                      41   0.002
gi|55956916 myosin IE [Homo sapiens]                                   41   0.002
gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Ho...    40   0.003
gi|27544941 myosin IF [Homo sapiens]                                   40   0.005
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  39   0.006
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...    39   0.006
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    39   0.006
gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]     39   0.006
gi|188536004 zinc finger protein 469 [Homo sapiens]                    39   0.008
gi|29648315 small G protein signaling modulator 3 [Homo sapiens]       39   0.008
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                37   0.023
gi|5729856 GRB2-related adaptor protein [Homo sapiens]                 37   0.029
gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]             37   0.038
gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]             37   0.038
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom...    37   0.038
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom...    37   0.038
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom...    37   0.038
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo...    37   0.038
gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ...    37   0.038
gi|50511947 cajalin 2 isoform b [Homo sapiens]                         37   0.038

>gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]
          Length = 380

 Score =  762 bits (1968), Expect = 0.0
 Identities = 380/380 (100%), Positives = 380/380 (100%)

Query: 1   MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP 60
           MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP
Sbjct: 1   MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP 60

Query: 61  TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS 120
           TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS
Sbjct: 61  TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDS 120

Query: 121 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV 180
           PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV
Sbjct: 121 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV 180

Query: 181 HTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHA 240
           HTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHA
Sbjct: 181 HTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHA 240

Query: 241 RPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDP 300
           RPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDP
Sbjct: 241 RPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDP 300

Query: 301 QHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD 360
           QHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD
Sbjct: 301 QHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD 360

Query: 361 DAELAGTEEQLQGLSLAGAP 380
           DAELAGTEEQLQGLSLAGAP
Sbjct: 361 DAELAGTEEQLQGLSLAGAP 380


>gi|48762709 SAM domain, SH3 domain and nuclear localization
           signals, 1 [Homo sapiens]
          Length = 373

 Score =  257 bits (656), Expect = 1e-68
 Identities = 166/369 (44%), Positives = 221/369 (59%), Gaps = 20/369 (5%)

Query: 1   MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP 60
           ML+RKPSN SEKE  QK K    RSSSF +F + + +S    +      +  P + SG  
Sbjct: 1   MLKRKPSNVSEKEKHQKPK----RSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQ 56

Query: 61  TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEG-SASPTSPDYSLD 119
           +      +G  LGKK RA IS TM +K+GK  +KALSEE  +  E+G +A P      + 
Sbjct: 57  SK--TSNNGGGLGKKMRA-ISWTMKKKVGKKYIKALSEEKDE--EDGENAHPYRNSDPVI 111

Query: 120 SPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGS-GSFGEEPPAPQYTGPFCGRA 178
               EK++L  S+  +       + +S+G   CS    +  SF  +   P Y+GPFCGRA
Sbjct: 112 GTHTEKVSLKASDSMDSLYS--GQSSSSGITSCSDGTSNRDSFRLDDDGP-YSGPFCGRA 168

Query: 179 RVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVG 238
           RVHTDFTPSPYD DSLK++KGD+I II K P+G W G+LN KVG+FKFIYVDV+ EE   
Sbjct: 169 RVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAA 228

Query: 239 HAR-PSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNI 297
             +  + R+S  K  K KTL E LERI L+E+TSTLLLNGY+TLED K+++E+HL ELNI
Sbjct: 229 PKKIKANRRSNSK--KSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNI 286

Query: 298 MDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCF---EG 354
            +P  R +LL+AAE  L+ +   E+  E    S             D PRDSGC+     
Sbjct: 287 ENPDDRRRLLSAAENFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGN 346

Query: 355 SESGRDDAE 363
           S++G++D E
Sbjct: 347 SDNGKEDLE 355


>gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]
          Length = 1247

 Score =  244 bits (622), Expect = 1e-64
 Identities = 144/295 (48%), Positives = 185/295 (62%), Gaps = 20/295 (6%)

Query: 72  LGKKWRAVISRTMNRKMGKMMVKALSEEMA--DTLEEGSASPTSPDYS-LDSP------G 122
           LGKK ++V   TM ++M K    ++SE+ +  D +  GS  P+ PD   LD P       
Sbjct: 450 LGKKVKSV-KETMRKRMSKKYSSSVSEQDSGLDGMP-GSPPPSQPDPEHLDKPKLKAGGS 507

Query: 123 PEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHT 182
            E +  + S Q       +S   S+ S   S     G   EEPP   Y GPFCGRARVHT
Sbjct: 508 VESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKSEDGD-DEEPP---YRGPFCGRARVHT 563

Query: 183 DFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARP 242
           DFTPSPYD DSLKL+KGD+I II KPP+GTW+GLLN KVG+FKFIYVDVL E+     RP
Sbjct: 564 DFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRP 623

Query: 243 SRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQH 302
           +RR+ KG+ P+PK++ +LL+RI L+EH  T L NGY+ L+ FK L E  L+ELNI DP+H
Sbjct: 624 TRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEH 683

Query: 303 RAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSES 357
           RA LLTA ELL +YD+ S+++      SQE +           PRDSGC+E SE+
Sbjct: 684 RAVLLTAVELLQEYDSNSDQS-----GSQEKLLVDSQGLSGCSPRDSGCYESSEN 733


>gi|140161500 ankyrin repeat and sterile alpha motif domain
           containing 1 [Homo sapiens]
          Length = 1134

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 7/84 (8%)

Query: 244 RRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLE--DFKELRETHLNELNIMDPQ 301
           R++  G R   +++ E LE IGL+++ S LLLNG+  +       + E  L ++ I DPQ
Sbjct: 688 RQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQ 747

Query: 302 HRAKLLTAAELL-----LDYDTGS 320
           HR KLL AA  L     L YD  S
Sbjct: 748 HRRKLLQAARSLPKVKALGYDGNS 771



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 15/57 (26%), Positives = 32/57 (56%), Gaps = 1/57 (1%)

Query: 254 PKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHL-NELNIMDPQHRAKLLTA 309
           P ++   L+ +GL+++  + L +GY +++  K L E  L N L +    HR +++ +
Sbjct: 772 PPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIAS 828


>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
           sapiens]
          Length = 506

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 32/87 (36%), Positives = 41/87 (47%), Gaps = 12/87 (13%)

Query: 155 SPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDH-----DSLKLQKGDVIQIIEKPP 209
           S G  + G   PAP       G A++ +    + Y       D L L+KGD++ I EK  
Sbjct: 420 SGGQSNPGSSTPAP-------GAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKE 472

Query: 210 VGTWLGLLNGKVGSFKFIYVDVLPEEA 236
            G W G LNGK G F   YV+ LP  A
Sbjct: 473 EGWWFGSLNGKKGHFPAAYVEELPSNA 499


>gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo
           sapiens]
          Length = 428

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 32/87 (36%), Positives = 41/87 (47%), Gaps = 12/87 (13%)

Query: 155 SPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDH-----DSLKLQKGDVIQIIEKPP 209
           S G  + G   PAP       G A++ +    + Y       D L L+KGD++ I EK  
Sbjct: 342 SGGQSNPGSSTPAP-------GAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKE 394

Query: 210 VGTWLGLLNGKVGSFKFIYVDVLPEEA 236
            G W G LNGK G F   YV+ LP  A
Sbjct: 395 EGWWFGSLNGKKGHFPAAYVEELPSNA 421


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 13/96 (13%)

Query: 173 PFCGRARVH------------TDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGK 220
           P C R R H             +F+ SP   D LKLQ G+++++I++   G WLG  NG+
Sbjct: 69  PRCARRRGHPAKHPRPQRWCKVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQ 128

Query: 221 VGSFKFIYVDVLPEEAVGHARPSRRQ-SKGKRPKPK 255
           +G+F   +V++L         P     S G +  PK
Sbjct: 129 LGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPK 164



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 192 DSLKLQKGDVIQIIEKPPVGTWL-GLLNGKVGSFKFIYVDVLPE--EAVGHAR----PSR 244
           D L L  GDV++ +   P   WL G   G+ G F    V  +PE     G AR      R
Sbjct: 15  DELSLAPGDVVRQVRWVPARGWLRGEFGGRYGLFPERLVQEIPETLRGSGEARRPRCARR 74

Query: 245 RQSKGKRPKPK 255
           R    K P+P+
Sbjct: 75  RGHPAKHPRPQ 85


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/60 (35%), Positives = 34/60 (56%)

Query: 177 RARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEA 236
           R R    F+  P + D L+L+ GD+I+++ +   G W G+LNGK G F   ++  L  E+
Sbjct: 63  RRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGES 122



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 188 PYD---HDSLKLQKGDVIQIIEKP--PVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARP 242
           PY+    D L +++GD++ +I K    VG W G LNG+ G F   +V +LP +       
Sbjct: 240 PYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDF------ 293

Query: 243 SRRQSKGKRPKPKTLHELLERIGLEE 268
            +  ++ K+P P +   + +  G  E
Sbjct: 294 EKEGNRPKKPPPPSAPVIKQGAGTTE 319


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/60 (35%), Positives = 34/60 (56%)

Query: 177 RARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEA 236
           R R    F+  P + D L+L+ GD+I+++ +   G W G+LNGK G F   ++  L  E+
Sbjct: 100 RRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGES 159



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 188 PYD---HDSLKLQKGDVIQIIEKP--PVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARP 242
           PY+    D L +++GD++ +I K    VG W G LNG+ G F   +V +LP +       
Sbjct: 277 PYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDF------ 330

Query: 243 SRRQSKGKRPKPKTLHELLERIGLEE 268
            +  ++ K+P P +   + +  G  E
Sbjct: 331 EKEGNRPKKPPPPSAPVIKQGAGTTE 356



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 7/69 (10%)

Query: 192 DSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKR 251
           D L +  G++I  I K   G W G +NG+ G F   +V  + +E        ++     +
Sbjct: 16  DELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKE-------MKKDPLTNK 68

Query: 252 PKPKTLHEL 260
              K LHE+
Sbjct: 69  APEKPLHEV 77


>gi|41327712 v-crk sarcoma virus CT10 oncogene homolog isoform a
           [Homo sapiens]
          Length = 304

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 4/96 (4%)

Query: 142 SRQASTGSELCSPSPGS-GSFGEEPPAPQY-TGPFCGRARVHTDFTPSPYDHDSLKLQKG 199
           +++ S    L  P PG         P P    GP    ARV     P+ YD  +L L+ G
Sbjct: 204 NQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIY--ARVIQKRVPNAYDKTALALEVG 261

Query: 200 DVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEE 235
           +++++ +    G W G  NGK G F F +V +L ++
Sbjct: 262 ELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQ 297



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 39/157 (24%), Positives = 55/157 (35%), Gaps = 19/157 (12%)

Query: 107 GSASPTSPDYSLDSPGPEKMALAFSEQEEHELPVLSR-------QASTGSELCSPS-PGS 158
           G   P  P  +   PG     L   +QE   LP L           +T  E  S S  GS
Sbjct: 66  GPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGS 125

Query: 159 GSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGL-L 217
           G    +  A      F        DF  +  D + L  +KGD+++I +KP    W     
Sbjct: 126 GVILRQEEAEYVRALF--------DFNGN--DEEDLPFKKGDILRIRDKPEEQWWNAEDS 175

Query: 218 NGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKP 254
            GK G     YV+     +   +       +G  P+P
Sbjct: 176 EGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQP 212


>gi|11321634 CD2-associated protein [Homo sapiens]
          Length = 639

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 53/205 (25%), Positives = 80/205 (39%), Gaps = 30/205 (14%)

Query: 81  SRTMNRKMGKM---MVKAL-------SEEMADTLEEGSASPTSPDYSLDSPG-------- 122
           S T+N K+G      VK L       + E  D  E   A PTSP  SL +          
Sbjct: 147 SGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVT 206

Query: 123 -PEKM-ALAFSEQ-EEHELPVLSRQASTGSELCSP-------SPGSGSFGEEPPAPQYTG 172
            P+K+  + F +  +E  + + +R +S+ +E   P       S G  +   E       G
Sbjct: 207 QPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEG 266

Query: 173 PFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPP--VGTWLGLLNGKVGSFKFIYVD 230
               +    T F     + D L  ++G++I +I K     G W G LNGK G F   +  
Sbjct: 267 KIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAV 326

Query: 231 VLPEEAVGHARPSRRQSKGKRPKPK 255
            + E      +P +     K P PK
Sbjct: 327 QINELDKDFPKPKKPPPPAKAPAPK 351



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 21/61 (34%), Positives = 31/61 (50%)

Query: 188 PYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQS 247
           P + D L+L+ GD+I I E+   G W G LN K+G F   +V  L     G    ++  S
Sbjct: 121 PQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDS 180

Query: 248 K 248
           +
Sbjct: 181 E 181


>gi|55956916 myosin IE [Homo sapiens]
          Length = 1108

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 34/111 (30%), Positives = 41/111 (36%), Gaps = 20/111 (18%)

Query: 139  PVLSRQASTGSELCSPSPGS---------GSFGEEPPAPQYTGPFCGRARVHTDFTPS-- 187
            P L RQ ST S+  S +P S         G+ G          P  GR +      P   
Sbjct: 995  PPLPRQQSTSSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVP 1054

Query: 188  ---------PYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYV 229
                       D D L     D+I II++ P G W G L GK G F   YV
Sbjct: 1055 QCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYV 1105


>gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Homo
           sapiens]
          Length = 1118

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 42/147 (28%), Positives = 56/147 (38%), Gaps = 33/147 (22%)

Query: 121 PGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARV 180
           PG +       E+EE E            E  + + G G  G + P P +T  F   A  
Sbjct: 20  PGEDGAGAGAEEEEEEE------------EEAAAAVGPGELGCDAPLPYWTAVFEYEAA- 66

Query: 181 HTDFTPSPYDHDSLKLQKGDVIQIIEKPPV-----GTWLGLLNGKVGSFKFIYVDVLPEE 235
                      D L L+ GDV++++ K        G W G LN +VG F   Y  V P  
Sbjct: 67  ---------GEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNY--VTPRS 115

Query: 236 AVGHARPSRRQSKGKRPKPKTLHELLE 262
           A      SR Q  G+ P      +LLE
Sbjct: 116 AFS----SRCQPGGEDPSCYPPIQLLE 138


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 11/108 (10%)

Query: 123  PEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHT 182
            P +    F    +  +  + R+ S G     P PG    G   P P+  GP C     + 
Sbjct: 1000 PSEHNTEFLNVPDQGMAGMQRKRSVGQR---PVPG---VGRPKPQPRTHGPRCRALYQYV 1053

Query: 183  DFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVD 230
                   D D L     +VI+I+ + P G W G L+G+ G F   YV+
Sbjct: 1054 G-----QDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVE 1096


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 4/117 (3%)

Query: 253 KPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAEL 312
           KP  L   L  IGL ++   L+ NGY+ ++   ++    L E+ I    H+ KL+ A   
Sbjct: 542 KPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRK 601

Query: 313 LLDYDTGSEEAEEGA----ESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRDDAELA 365
           L +         EG     ++ Q      +  P    P  + C     +   D+EL+
Sbjct: 602 LAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELS 658



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 6/42 (14%)

Query: 189 YDHDSLKLQKGDVIQIIEKPPVGTWLGLL------NGKVGSF 224
           YD  SL ++ GD+I ++E+ P G W G +      N +VG F
Sbjct: 296 YDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYF 337


>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
           [Homo sapiens]
          Length = 303

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 5/88 (5%)

Query: 144 QASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQ 203
           Q +T     S SPG+      P      GP   +A       P  YD  +L L+ GD+++
Sbjct: 211 QTTTPLPAVSGSPGAAI---TPLPSTQNGPVFAKAIQKR--VPCAYDKTALALEVGDIVK 265

Query: 204 IIEKPPVGTWLGLLNGKVGSFKFIYVDV 231
           +      G W G +NG+ G F F +V +
Sbjct: 266 VTRMNINGQWEGEVNGRKGLFPFTHVKI 293



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 41/184 (22%), Positives = 72/184 (39%), Gaps = 16/184 (8%)

Query: 81  SRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDSPGPEKMALAFSEQEEHELPV 140
           +R   ++ G  +V+  S    D +   S +     Y ++S    +  +   +QE   LP 
Sbjct: 26  TRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIG--DQEFDHLPA 83

Query: 141 LSR----QASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDH----- 191
           L           + L  P+P   S    PP    + P    A  + ++  + YD      
Sbjct: 84  LLEFYKIHYLDTTTLIEPAPRYPS----PPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDA 139

Query: 192 DSLKLQKGDVIQIIEKPPVGTWLGL-LNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGK 250
           + L  +KG+++ IIEKP    W     +G+VG     YV+ L   +      +R  +   
Sbjct: 140 EDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYG 199

Query: 251 RPKP 254
            P+P
Sbjct: 200 IPEP 203


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
          Length = 1258

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 261  LERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAEL 312
            L  IGLE +   L+ NG+  LE   ++ E  L E  + DP H+  LL   +L
Sbjct: 1205 LRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQL 1256


>gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]
          Length = 173

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 17/64 (26%), Positives = 36/64 (56%)

Query: 257 LHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDY 316
           ++E L+ + L ++  + + NGY  LE  K++ +  L+ + ++ P HR ++L A   L + 
Sbjct: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65

Query: 317 DTGS 320
           D  +
Sbjct: 66  DANA 69


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 44/189 (23%), Positives = 66/189 (34%), Gaps = 29/189 (15%)

Query: 3    RRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVPTP 62
            R  PS+ ++  P Q  K  L+   S     +  P SP   E +     + P  D      
Sbjct: 2515 RGDPSHVTQPPPAQGSKEVLRAPGS-PHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDE 2573

Query: 63   EDAGKSGKKLGKKWR--------AVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSP 114
                ++ K+ G++WR        +      N+K GK+  + L EE        S  P S 
Sbjct: 2574 LHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREE--------SILPVSA 2625

Query: 115  DYSLDSPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPF 174
            D   D  G                P ++  A++ S   S   G  + GE+PP     GP 
Sbjct: 2626 DVISDGRGSRPS------------PAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPG 2673

Query: 175  CGRARVHTD 183
                   TD
Sbjct: 2674 VMEGAAETD 2682


>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
          Length = 749

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 177 RARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEA 236
           RA+   DF    +D D L  +K D+I I+ +     W+G LNG  G F   +V+VL E +
Sbjct: 484 RAKALLDF--ERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERS 541


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 48/176 (27%), Positives = 73/176 (41%), Gaps = 29/176 (16%)

Query: 7    SNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVPTPEDAG 66
            S A +K   Q+  LSL R SS    + +    P    +  +LDD+    DS +   E+AG
Sbjct: 1052 SKALQKLAAQEGPLSLSRCSSLSSLSSAGRPGP---SEGGDLDDS----DSSLEGLEEAG 1104

Query: 67   KSGKKLGKKWRA-------VISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLD 119
             S  +L   WRA       V      R  G+ +           +E+ + S +S +Y  +
Sbjct: 1105 PSEAELDSTWRAPGATSLPVAIPAPRRNRGRGL----------GVEDATPSSSSENYVQE 1154

Query: 120  SPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSF--GEEPPAPQYTGP 173
            +P       + S     E P ++  +S  SE CS   GSG+    E P +P  T P
Sbjct: 1155 TPLVLSRCSSVSSLGSFESPSIA--SSIPSEPCS-GQGSGTISPSELPDSPGQTMP 1207


>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
          Length = 217

 Score = 37.0 bits (84), Expect = 0.029
 Identities = 18/54 (33%), Positives = 26/54 (48%)

Query: 176 GRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYV 229
           G       F  S  D   L  ++GD+I+++E+P    W G   G+VG F   YV
Sbjct: 159 GACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYV 212


>gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]
          Length = 380

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 14/102 (13%)

Query: 192 DSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKR 251
           D L L KG  + ++EK   G W G  NG++G F   YV    +EA   +       KG  
Sbjct: 128 DELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAESPSFLSLRKG-- 185

Query: 252 PKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLN 293
                         L     + +L+  QTL  F  + E  LN
Sbjct: 186 ------------ASLSNGQGSRVLHVVQTLYPFSSVTEEELN 215


>gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]
          Length = 380

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 14/102 (13%)

Query: 192 DSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKR 251
           D L L KG  + ++EK   G W G  NG++G F   YV    +EA   +       KG  
Sbjct: 128 DELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAESPSFLSLRKG-- 185

Query: 252 PKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLN 293
                         L     + +L+  QTL  F  + E  LN
Sbjct: 186 ------------ASLSNGQGSRVLHVVQTLYPFSSVTEEELN 215


>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
           sapiens]
          Length = 646

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 4/76 (5%)

Query: 180 VHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGH 239
           V   F     + D L   KGDVI +      G W G LNG+ G F   YV     E    
Sbjct: 11  VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV----REVKAS 66

Query: 240 ARPSRRQSKGKRPKPK 255
            +P   +S   +  PK
Sbjct: 67  EKPVSPKSGTLKSPPK 82


>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
           sapiens]
          Length = 753

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 4/76 (5%)

Query: 180 VHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGH 239
           V   F     + D L   KGDVI +      G W G LNG+ G F   YV     E    
Sbjct: 139 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV----REVKAS 194

Query: 240 ARPSRRQSKGKRPKPK 255
            +P   +S   +  PK
Sbjct: 195 EKPVSPKSGTLKSPPK 210


>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
           sapiens]
          Length = 803

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 4/76 (5%)

Query: 180 VHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGH 239
           V   F     + D L   KGDVI +      G W G LNG+ G F   YV     E    
Sbjct: 189 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV----REVKAS 244

Query: 240 ARPSRRQSKGKRPKPK 255
            +P   +S   +  PK
Sbjct: 245 EKPVSPKSGTLKSPPK 260


>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
           sapiens]
          Length = 782

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 4/76 (5%)

Query: 180 VHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGH 239
           V   F     + D L   KGDVI +      G W G LNG+ G F   YV     E    
Sbjct: 168 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV----REVKAS 223

Query: 240 ARPSRRQSKGKRPKPK 255
            +P   +S   +  PK
Sbjct: 224 EKPVSPKSGTLKSPPK 239


>gi|4505573 PAK-interacting exchange factor beta isoform a [Homo
           sapiens]
          Length = 646

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 4/76 (5%)

Query: 180 VHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGH 239
           V   F     + D L   KGDVI +      G W G LNG+ G F   YV     E    
Sbjct: 11  VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV----REVKAS 66

Query: 240 ARPSRRQSKGKRPKPK 255
            +P   +S   +  PK
Sbjct: 67  EKPVSPKSGTLKSPPK 82


>gi|50511947 cajalin 2 isoform b [Homo sapiens]
          Length = 510

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 2/67 (2%)

Query: 249 GKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLE--DFKELRETHLNELNIMDPQHRAKL 306
           G R   +T+ + LE IGL ++ + L+ NG+  ++      + +  L E+ I++  HR ++
Sbjct: 33  GPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRI 92

Query: 307 LTAAELL 313
           L A +LL
Sbjct: 93  LQAIQLL 99



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 1/57 (1%)

Query: 254 PKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHL-NELNIMDPQHRAKLLTA 309
           P ++ E L+ I L ++T   L+NGY +++  K++ E  L N L I    HR ++L +
Sbjct: 112 PTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILAS 168


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,347,003
Number of Sequences: 37866
Number of extensions: 925370
Number of successful extensions: 3390
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 3124
Number of HSP's gapped (non-prelim): 372
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.