Guide to the Human Genome
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Search of human proteins with 94536784

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94536784 coiled-coil domain containing 51 [Homo sapiens]
         (411 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94536784 coiled-coil domain containing 51 [Homo sapiens]           801   0.0  
gi|93277096 limbin [Homo sapiens]                                      44   2e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           44   3e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           44   3e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           44   3e-04
gi|210032790 hypothetical protein LOC27146 [Homo sapiens]              44   3e-04
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    40   0.005
gi|31542634 filamin A interacting protein 1 [Homo sapiens]             39   0.009
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         39   0.011
gi|21361517 UBX domain protein 1 [Homo sapiens]                        39   0.011
gi|110347443 TATA element modulatory factor 1 [Homo sapiens]           38   0.015
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    38   0.015
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    38   0.015
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]          38   0.015
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]          38   0.015
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            38   0.019
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    38   0.019
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    38   0.019
gi|221219020 NYD-SP11 protein [Homo sapiens]                           37   0.025
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 37   0.025
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi...    37   0.025
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    37   0.033
gi|126723390 ankyrin repeat domain 24 [Homo sapiens]                   37   0.033
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]                    36   0.056
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]                      36   0.056
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    36   0.056
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    36   0.056
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     36   0.056
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    36   0.056
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    36   0.073

>gi|94536784 coiled-coil domain containing 51 [Homo sapiens]
          Length = 411

 Score =  801 bits (2069), Expect = 0.0
 Identities = 411/411 (100%), Positives = 411/411 (100%)

Query: 1   MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRL 60
           MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRL
Sbjct: 1   MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRL 60

Query: 61  PALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAR 120
           PALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAR
Sbjct: 61  PALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAR 120

Query: 121 EDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFS 180
           EDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFS
Sbjct: 121 EDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFS 180

Query: 181 LFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKG 240
           LFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKG
Sbjct: 181 LFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKG 240

Query: 241 PVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS 300
           PVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS
Sbjct: 241 PVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS 300

Query: 301 AALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSF 360
           AALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSF
Sbjct: 301 AALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSF 360

Query: 361 LLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS 411
           LLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS
Sbjct: 361 LLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS 411


>gi|93277096 limbin [Homo sapiens]
          Length = 1308

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 2/107 (1%)

Query: 94  EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153
           E R  Q  V EA +    A   + + R  +E H A L+E+++RLD+ + +D + L L+  
Sbjct: 685 EQRREQASVGEAFRTVEDAGQYLHQKRSLMEEHGATLEELQERLDQAALDDLRTLTLSLF 744

Query: 154 EHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKE-RTRAER 199
           E +   E +RL+ + +  E  +R    LF   + E H KE   RAE+
Sbjct: 745 E-KATDELRRLQNSAMTQELLKRGVPWLFLQQILEEHGKEMAARAEQ 790


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 71/318 (22%), Positives = 127/318 (39%), Gaps = 37/318 (11%)

Query: 94   EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153
            +++E QG+  + E+    A   ++ A+ +LE     L E   +  R+S+E S        
Sbjct: 1285 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1344

Query: 154  EHRMLQEEKRLRTAY---LRAEDSE----REKFSLFSAAVRESHEKERTRAERTKNW-SL 205
               +LQEE R + A    +RA ++E    RE+    +AA   +  + +T   +   W   
Sbjct: 1345 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRR 1404

Query: 206  IGSVLGALIGVAGSTYVNRV---------RLQELKALLLEAQKGPVSLQEAI-------- 248
                 GAL   AG     R          RL E    +   ++G   LQ+ +        
Sbjct: 1405 QEEEAGAL--EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1462

Query: 249  --REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS--AALK 304
              R+  S+  ++QR    L+ + +  V  A   ++     G    R+R+   LS   AL+
Sbjct: 1463 QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG----REREARALSLTRALE 1518

Query: 305  EQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQ 364
            E+     ++      LR +L+ L  +   +   V  ++ A    + E A   + + + E 
Sbjct: 1519 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR--VAEQAANDLRAQVTEL 1576

Query: 365  GSMILALSDTEQRLEAQV 382
               + A  D + RLE  V
Sbjct: 1577 EDELTAAEDAKLRLEVTV 1594



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 61/249 (24%), Positives = 102/249 (40%), Gaps = 22/249 (8%)

Query: 26   LGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHR-LPALGRALGHSIQQRATSTAKTWWD 84
            L ++L  T            E+   ++ALG   R + A    L   +++ A +  +   +
Sbjct: 1331 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1390

Query: 85   RYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144
                   L+E R  Q +   A +    AR       E L    A+  E  DRL+R  R  
Sbjct: 1391 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1450

Query: 145  SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF-----SAAVRESHEKERTRAER 199
             Q L+ AT++   L+++++L    +   + ++ KF        +A +R   E+ER  AE 
Sbjct: 1451 QQELDDATMD---LEQQRQL----VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG 1503

Query: 200  TKNWSLIGSVLGALIGVAGS----TYVNRVRLQELKALLL---EAQKGPVSLQEAIR--E 250
             +  +   S+  AL     +       NR    EL+ALL    +  K    L+ A R  E
Sbjct: 1504 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAE 1563

Query: 251  QASSYSRQQ 259
            QA++  R Q
Sbjct: 1564 QAANDLRAQ 1572



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 64/311 (20%), Positives = 111/311 (35%), Gaps = 56/311 (18%)

Query: 115  LVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELA------------TLEHRMLQ--- 159
            L +   E+  +H+A ++E+R R  +   E ++ LE A             LE  + +   
Sbjct: 1204 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1263

Query: 160  EEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKN----WSLIGSVLGALIG 215
            E   L+TA    E   R            + + ER RAE  +      + + +V GAL  
Sbjct: 1264 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1323

Query: 216  VAGSTYVNRVRLQELKALLLEAQK---------------------GPVSLQEAIREQASS 254
                T      L   +A L +AQ+                         L+E + E+A++
Sbjct: 1324 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAA 1383

Query: 255  YSRQQRDLHNLMVDL---RGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311
              R  R+L      L   R          ++G +A     R+ +      AL ++L+   
Sbjct: 1384 RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE------ALTQRLAEKT 1437

Query: 312  QVHSCLE-GLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILA 370
            +    LE G R     L+     +    QLV +      +E         L E+ + +L 
Sbjct: 1438 ETVDRLERGRRRLQQELDDATMDLEQQRQLVST------LEKKQRKFDQLLAEEKAAVLR 1491

Query: 371  LSDTEQRLEAQ 381
              +  +R EA+
Sbjct: 1492 AVEERERAEAE 1502



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 45/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%)

Query: 92   LNEVREAQGKVTEAEKVF---MVARGLVREAREDL-EVHQAKLKEVRDRLDRVSRED--- 144
            L  +REAQ  + EA++      VAR    + R DL E  +A   E+ D LD  + +    
Sbjct: 1135 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1194

Query: 145  SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204
            S+  +  T   + L+EE R+  A   A    R++       + E  E+ R      +   
Sbjct: 1195 SKREQEVTELKKTLEEETRIHEA---AVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251

Query: 205  L-----IGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259
            L     +  +   L  +  +      R + L+  L E Q      + A  E A    R Q
Sbjct: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311

Query: 260  RDLHNL 265
             +L N+
Sbjct: 1312 AELENV 1317



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 62/277 (22%), Positives = 104/277 (37%), Gaps = 52/277 (18%)

Query: 94   EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153
            EV E QG+V + E+       L  + R + E+  A+ +E R RL   +R+    L ++ L
Sbjct: 899  EVGELQGRVAQLEEE---RARLAEQLRAEAELC-AEAEETRGRL--AARKQELELVVSEL 952

Query: 154  EHRMLQEE----------KRLRT------AYLRAEDSEREKFSLFSAAVRESHEK----- 192
            E R+ +EE          KRL+       A+L AE+  R+K  L         +K     
Sbjct: 953  EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1012

Query: 193  ---ERTRAERTKNWSLIGSVLGALIGVAGS-----TYVNRVRLQ------ELKALLLEAQ 238
               E   ++ +K   L+   L      A         +N++RL+      +++  L + +
Sbjct: 1013 LLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEE 1072

Query: 239  KGPVSLQEAIRE---QASSYSRQQRDLHNLMVDLRG--------LVHAAGPGQDSGSQAG 287
            KG   L++  R    ++S    Q  +      +LR         L  A    +D G    
Sbjct: 1073 KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARA 1132

Query: 288  SPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQL 324
                  R+     A  +E L   R   +  E  R  L
Sbjct: 1133 QLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1169


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 71/318 (22%), Positives = 127/318 (39%), Gaps = 37/318 (11%)

Query: 94   EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153
            +++E QG+  + E+    A   ++ A+ +LE     L E   +  R+S+E S        
Sbjct: 1277 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1336

Query: 154  EHRMLQEEKRLRTAY---LRAEDSE----REKFSLFSAAVRESHEKERTRAERTKNW-SL 205
               +LQEE R + A    +RA ++E    RE+    +AA   +  + +T   +   W   
Sbjct: 1337 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRR 1396

Query: 206  IGSVLGALIGVAGSTYVNRV---------RLQELKALLLEAQKGPVSLQEAI-------- 248
                 GAL   AG     R          RL E    +   ++G   LQ+ +        
Sbjct: 1397 QEEEAGAL--EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1454

Query: 249  --REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS--AALK 304
              R+  S+  ++QR    L+ + +  V  A   ++     G    R+R+   LS   AL+
Sbjct: 1455 QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG----REREARALSLTRALE 1510

Query: 305  EQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQ 364
            E+     ++      LR +L+ L  +   +   V  ++ A    + E A   + + + E 
Sbjct: 1511 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR--VAEQAANDLRAQVTEL 1568

Query: 365  GSMILALSDTEQRLEAQV 382
               + A  D + RLE  V
Sbjct: 1569 EDELTAAEDAKLRLEVTV 1586



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 61/249 (24%), Positives = 102/249 (40%), Gaps = 22/249 (8%)

Query: 26   LGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHR-LPALGRALGHSIQQRATSTAKTWWD 84
            L ++L  T            E+   ++ALG   R + A    L   +++ A +  +   +
Sbjct: 1323 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1382

Query: 85   RYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144
                   L+E R  Q +   A +    AR       E L    A+  E  DRL+R  R  
Sbjct: 1383 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1442

Query: 145  SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF-----SAAVRESHEKERTRAER 199
             Q L+ AT++   L+++++L    +   + ++ KF        +A +R   E+ER  AE 
Sbjct: 1443 QQELDDATMD---LEQQRQL----VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG 1495

Query: 200  TKNWSLIGSVLGALIGVAGS----TYVNRVRLQELKALLL---EAQKGPVSLQEAIR--E 250
             +  +   S+  AL     +       NR    EL+ALL    +  K    L+ A R  E
Sbjct: 1496 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAE 1555

Query: 251  QASSYSRQQ 259
            QA++  R Q
Sbjct: 1556 QAANDLRAQ 1564



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 64/311 (20%), Positives = 111/311 (35%), Gaps = 56/311 (18%)

Query: 115  LVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELA------------TLEHRMLQ--- 159
            L +   E+  +H+A ++E+R R  +   E ++ LE A             LE  + +   
Sbjct: 1196 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1255

Query: 160  EEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKN----WSLIGSVLGALIG 215
            E   L+TA    E   R            + + ER RAE  +      + + +V GAL  
Sbjct: 1256 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1315

Query: 216  VAGSTYVNRVRLQELKALLLEAQK---------------------GPVSLQEAIREQASS 254
                T      L   +A L +AQ+                         L+E + E+A++
Sbjct: 1316 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAA 1375

Query: 255  YSRQQRDLHNLMVDL---RGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311
              R  R+L      L   R          ++G +A     R+ +      AL ++L+   
Sbjct: 1376 RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE------ALTQRLAEKT 1429

Query: 312  QVHSCLE-GLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILA 370
            +    LE G R     L+     +    QLV +      +E         L E+ + +L 
Sbjct: 1430 ETVDRLERGRRRLQQELDDATMDLEQQRQLVST------LEKKQRKFDQLLAEEKAAVLR 1483

Query: 371  LSDTEQRLEAQ 381
              +  +R EA+
Sbjct: 1484 AVEERERAEAE 1494



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 45/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%)

Query: 92   LNEVREAQGKVTEAEKVF---MVARGLVREAREDL-EVHQAKLKEVRDRLDRVSRED--- 144
            L  +REAQ  + EA++      VAR    + R DL E  +A   E+ D LD  + +    
Sbjct: 1127 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1186

Query: 145  SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204
            S+  +  T   + L+EE R+  A   A    R++       + E  E+ R      +   
Sbjct: 1187 SKREQEVTELKKTLEEETRIHEA---AVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243

Query: 205  L-----IGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259
            L     +  +   L  +  +      R + L+  L E Q      + A  E A    R Q
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303

Query: 260  RDLHNL 265
             +L N+
Sbjct: 1304 AELENV 1309



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 62/277 (22%), Positives = 104/277 (37%), Gaps = 52/277 (18%)

Query: 94   EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153
            EV E QG+V + E+       L  + R + E+  A+ +E R RL   +R+    L ++ L
Sbjct: 891  EVGELQGRVAQLEEE---RARLAEQLRAEAELC-AEAEETRGRL--AARKQELELVVSEL 944

Query: 154  EHRMLQEE----------KRLRT------AYLRAEDSEREKFSLFSAAVRESHEK----- 192
            E R+ +EE          KRL+       A+L AE+  R+K  L         +K     
Sbjct: 945  EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1004

Query: 193  ---ERTRAERTKNWSLIGSVLGALIGVAGS-----TYVNRVRLQ------ELKALLLEAQ 238
               E   ++ +K   L+   L      A         +N++RL+      +++  L + +
Sbjct: 1005 LLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEE 1064

Query: 239  KGPVSLQEAIRE---QASSYSRQQRDLHNLMVDLRG--------LVHAAGPGQDSGSQAG 287
            KG   L++  R    ++S    Q  +      +LR         L  A    +D G    
Sbjct: 1065 KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARA 1124

Query: 288  SPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQL 324
                  R+     A  +E L   R   +  E  R  L
Sbjct: 1125 QLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1161


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 71/318 (22%), Positives = 127/318 (39%), Gaps = 37/318 (11%)

Query: 94   EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153
            +++E QG+  + E+    A   ++ A+ +LE     L E   +  R+S+E S        
Sbjct: 1318 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1377

Query: 154  EHRMLQEEKRLRTAY---LRAEDSE----REKFSLFSAAVRESHEKERTRAERTKNW-SL 205
               +LQEE R + A    +RA ++E    RE+    +AA   +  + +T   +   W   
Sbjct: 1378 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRR 1437

Query: 206  IGSVLGALIGVAGSTYVNRV---------RLQELKALLLEAQKGPVSLQEAI-------- 248
                 GAL   AG     R          RL E    +   ++G   LQ+ +        
Sbjct: 1438 QEEEAGAL--EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1495

Query: 249  --REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS--AALK 304
              R+  S+  ++QR    L+ + +  V  A   ++     G    R+R+   LS   AL+
Sbjct: 1496 QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG----REREARALSLTRALE 1551

Query: 305  EQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQ 364
            E+     ++      LR +L+ L  +   +   V  ++ A    + E A   + + + E 
Sbjct: 1552 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR--VAEQAANDLRAQVTEL 1609

Query: 365  GSMILALSDTEQRLEAQV 382
               + A  D + RLE  V
Sbjct: 1610 EDELTAAEDAKLRLEVTV 1627



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 61/249 (24%), Positives = 102/249 (40%), Gaps = 22/249 (8%)

Query: 26   LGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHR-LPALGRALGHSIQQRATSTAKTWWD 84
            L ++L  T            E+   ++ALG   R + A    L   +++ A +  +   +
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423

Query: 85   RYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144
                   L+E R  Q +   A +    AR       E L    A+  E  DRL+R  R  
Sbjct: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483

Query: 145  SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF-----SAAVRESHEKERTRAER 199
             Q L+ AT++   L+++++L    +   + ++ KF        +A +R   E+ER  AE 
Sbjct: 1484 QQELDDATMD---LEQQRQL----VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG 1536

Query: 200  TKNWSLIGSVLGALIGVAGS----TYVNRVRLQELKALLL---EAQKGPVSLQEAIR--E 250
             +  +   S+  AL     +       NR    EL+ALL    +  K    L+ A R  E
Sbjct: 1537 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAE 1596

Query: 251  QASSYSRQQ 259
            QA++  R Q
Sbjct: 1597 QAANDLRAQ 1605



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 64/311 (20%), Positives = 111/311 (35%), Gaps = 56/311 (18%)

Query: 115  LVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELA------------TLEHRMLQ--- 159
            L +   E+  +H+A ++E+R R  +   E ++ LE A             LE  + +   
Sbjct: 1237 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296

Query: 160  EEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKN----WSLIGSVLGALIG 215
            E   L+TA    E   R            + + ER RAE  +      + + +V GAL  
Sbjct: 1297 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1356

Query: 216  VAGSTYVNRVRLQELKALLLEAQK---------------------GPVSLQEAIREQASS 254
                T      L   +A L +AQ+                         L+E + E+A++
Sbjct: 1357 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAA 1416

Query: 255  YSRQQRDLHNLMVDL---RGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311
              R  R+L      L   R          ++G +A     R+ +      AL ++L+   
Sbjct: 1417 RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE------ALTQRLAEKT 1470

Query: 312  QVHSCLE-GLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILA 370
            +    LE G R     L+     +    QLV +      +E         L E+ + +L 
Sbjct: 1471 ETVDRLERGRRRLQQELDDATMDLEQQRQLVST------LEKKQRKFDQLLAEEKAAVLR 1524

Query: 371  LSDTEQRLEAQ 381
              +  +R EA+
Sbjct: 1525 AVEERERAEAE 1535



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 45/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%)

Query: 92   LNEVREAQGKVTEAEKVF---MVARGLVREAREDL-EVHQAKLKEVRDRLDRVSRED--- 144
            L  +REAQ  + EA++      VAR    + R DL E  +A   E+ D LD  + +    
Sbjct: 1168 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1227

Query: 145  SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204
            S+  +  T   + L+EE R+  A   A    R++       + E  E+ R      +   
Sbjct: 1228 SKREQEVTELKKTLEEETRIHEA---AVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284

Query: 205  L-----IGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259
            L     +  +   L  +  +      R + L+  L E Q      + A  E A    R Q
Sbjct: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344

Query: 260  RDLHNL 265
             +L N+
Sbjct: 1345 AELENV 1350



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 62/277 (22%), Positives = 104/277 (37%), Gaps = 52/277 (18%)

Query: 94   EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153
            EV E QG+V + E+       L  + R + E+  A+ +E R RL   +R+    L ++ L
Sbjct: 932  EVGELQGRVAQLEEE---RARLAEQLRAEAELC-AEAEETRGRL--AARKQELELVVSEL 985

Query: 154  EHRMLQEE----------KRLRT------AYLRAEDSEREKFSLFSAAVRESHEK----- 192
            E R+ +EE          KRL+       A+L AE+  R+K  L         +K     
Sbjct: 986  EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1045

Query: 193  ---ERTRAERTKNWSLIGSVLGALIGVAGS-----TYVNRVRLQ------ELKALLLEAQ 238
               E   ++ +K   L+   L      A         +N++RL+      +++  L + +
Sbjct: 1046 LLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEE 1105

Query: 239  KGPVSLQEAIRE---QASSYSRQQRDLHNLMVDLRG--------LVHAAGPGQDSGSQAG 287
            KG   L++  R    ++S    Q  +      +LR         L  A    +D G    
Sbjct: 1106 KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARA 1165

Query: 288  SPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQL 324
                  R+     A  +E L   R   +  E  R  L
Sbjct: 1166 QLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1202


>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
          Length = 1060

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 60/284 (21%), Positives = 108/284 (38%), Gaps = 45/284 (15%)

Query: 120 REDLEVHQAKLKEVRDRLDRVSREDSQY-----LELATLEHRMLQEEKRLRTAYLRAEDS 174
           REDL+  +      R++L R  +E +Q       +L     R L+  ++ R   L+A + 
Sbjct: 624 REDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEE 683

Query: 175 EREKFSLFSAAVR-ESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKAL 233
             +K S  S  ++ ++H  E    E      L                  R R+Q  +AL
Sbjct: 684 RLKKESSHSLQIQHQTHRLELQALEEKARQEL---------------QEERERMQAQQAL 728

Query: 234 LLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSG---------- 283
           LLE      SL++ + EQ ++ S  Q+DL  L  +LR L       Q  G          
Sbjct: 729 LLE------SLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATE 782

Query: 284 -----SQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVV 338
                 QAGSPP            L E+   + Q+   +  LR +++  ++   ++    
Sbjct: 783 ERGGPGQAGSPPGAAGQGSGEGCGLWEE---NAQLQDAVRRLRAEVEQHQQEAQKLRDQR 839

Query: 339 QLVKSAAHPGLVEPADGAMPSFLLEQGSMILALSDTEQRLEAQV 382
           + ++           +        E  +M+   S  + +L+A++
Sbjct: 840 RFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARL 883



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 116 VREAREDLEVHQAKLKEVRD--RLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAED 173
           VR  R ++E HQ + +++RD  R    +++  +  E+ TL     +E + +   +  A+ 
Sbjct: 818 VRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQA 877

Query: 174 SEREKFSLFSAAVRESHEKERTRAERTKNWSLIG 207
             + + +   A +++S EK    A R ++  LIG
Sbjct: 878 QLQARLAALEAELKDSGEKPGKGASRPEDLQLIG 911


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
           sapiens]
          Length = 1478

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 71/307 (23%), Positives = 117/307 (38%), Gaps = 55/307 (17%)

Query: 50  EEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGL---NEVREAQGKVTEAE 106
           +++A   H  L    RAL    QQ+         ++ ++ VG    NE RE   ++  ++
Sbjct: 720 QQLAEARHREL----RALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQ 775

Query: 107 KVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHR-MLQEEKRLR 165
               V +G V+  +  +   QAK++   D  D+V  + S   E    EH+ ++Q+ K   
Sbjct: 776 AQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSM-AEAVLREHKTLVQQLKEQN 834

Query: 166 TAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRV 225
            A  RA   E  + S    A++E    E  + E                           
Sbjct: 835 EALNRAHVQELLQCSEREGALQEERADEAQQRE--------------------------- 867

Query: 226 RLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQ 285
             +EL+AL  E  +   S +EA  E A      Q  LH    D   L          G Q
Sbjct: 868 --EELRALQEELSQAKCSSEEAQLEHA----ELQEQLHRANTDTAEL----------GIQ 911

Query: 286 AGSPPTRDRDVDVLSAALKEQLSHSRQVHSC-LEGLREQLDGLEKTCSQMAGVVQLVKSA 344
             +       V+   A   ++L  +++  S   EGL  Q+ GL++    +   ++  K+A
Sbjct: 912 VCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAA 971

Query: 345 AH--PGL 349
           A   PGL
Sbjct: 972 AGSLPGL 978



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 60/264 (22%), Positives = 111/264 (42%), Gaps = 32/264 (12%)

Query: 118 EAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQ-EEKRLRTAYLRAEDSER 176
           E R +L+  + + K++R+R+ ++ RE+ +     + +   LQ E +R RTA   AED+ R
Sbjct: 234 EMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGRTA---AEDNVR 290

Query: 177 EKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLE 236
               L         + E T+A +     L   + G  +G A         L+ L+++   
Sbjct: 291 ----LTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESM--- 343

Query: 237 AQKGPVSLQEAIRE-QASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRD 295
                  LQ   +E +A+  S  +++ H  +    G +  A    D+ S      T+ R 
Sbjct: 344 -------LQPLAQELEATRDSLDKKNQH--LASFPGWLAMAQQKADTASD-----TKGRQ 389

Query: 296 VDVLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADG 355
             + S A +E      ++ + LE  R +++ + +   Q A + QLVK      L E A  
Sbjct: 390 EPIPSDAAQEMQELGEKLQA-LERERTKVEEVNR--QQSAQLEQLVKELQ---LKEDARA 443

Query: 356 AMPSFLLEQGSMILALSDTEQRLE 379
           ++   + E   +   LS   Q  +
Sbjct: 444 SLERLVKEMAPLQEELSGKGQEAD 467


>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
          Length = 1213

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 64/257 (24%), Positives = 104/257 (40%), Gaps = 37/257 (14%)

Query: 94  EVREAQGKVTEAEKVFMVARG---LVREAREDLEVHQAKLKEVRDRLDRVSREDS----Q 146
           EV EA     E EKV  V      L +E     +V++  + E+ DRL+   +E      +
Sbjct: 109 EVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISEL-DRLEEKQKETYRRMLE 167

Query: 147 YLELATLEHRM----LQEEKRLRTAYLRAEDS-----EREKFSLFSAAVRESHEKERTRA 197
            L LA   HR     L+ EK   T Y+   D      E+E+  L     +E   + R   
Sbjct: 168 QLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEK 227

Query: 198 ERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSY-- 255
           E  K  + +   L  L   A    +   R   ++ L L++QK    L + +RE+      
Sbjct: 228 ENAKRLNKLRDELVKLKSFA--LMLVDERQMHIEQLGLQSQKVQ-DLTQKLREEEEKLKA 284

Query: 256 --SRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQV 313
             S+ + D   L+       H A                 ++ + ++A L  Q SH+RQ+
Sbjct: 285 ITSKSKEDRQKLLKLEVDFEHKAS-------------RFSQEHEEMNAKLANQESHNRQL 331

Query: 314 HSCLEGLREQLDGLEKT 330
              L GL ++++ LE+T
Sbjct: 332 RLKLVGLTQRIEELEET 348



 Score = 35.4 bits (80), Expect = 0.095
 Identities = 49/248 (19%), Positives = 105/248 (42%), Gaps = 24/248 (9%)

Query: 92  LNEVREAQGKVTEAEKVFMV------ARGLVREAREDLEVHQAKLKEVRDRLDRVSREDS 145
           L + RE   K+ E EK +        A+ L +   E +++    L  V +R   + +   
Sbjct: 204 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 263

Query: 146 QYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF----SAAVRESHEKERTRAERTK 201
           Q  ++  L  ++ +EE++L+    ++++  ++   L       A R S E E   A+   
Sbjct: 264 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 323

Query: 202 NWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRD 261
             S    +   L+G+         R++EL+    E  K     +E ++E     ++ +  
Sbjct: 324 QESHNRQLRLKLVGLTQ-------RIEELE----ETNKNLQKAEEELQELRDKIAKGECG 372

Query: 262 LHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLR 321
             +LM ++  L       +    +     ++ R+   L   L+E+  HS+++   +E L+
Sbjct: 373 NSSLMAEVENLRKRVLEMEGKDEEITKTESQCRE---LRKKLQEEEHHSKELRLEVEKLQ 429

Query: 322 EQLDGLEK 329
           +++  LEK
Sbjct: 430 KRMSELEK 437


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 54/234 (23%), Positives = 93/234 (39%), Gaps = 33/234 (14%)

Query: 47  KRPEEVALGLHHRLPALGRALGHSIQQRATSTAK---TWWDRYEEFVGLNEVREAQGKVT 103
           ++ E+ + GL H++  L  +L    QQ      K   T  D  ++     E REA   + 
Sbjct: 540 QQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREAS--LR 597

Query: 104 EAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQ-YLELATLEHRMLQEEK 162
           E +        L +E    LE+ Q +L+   +  D      +Q   E A L  ++ + + 
Sbjct: 598 ERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQA 657

Query: 163 RLRTAYLRAEDSEREKFSL---FSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGS 219
            + TA     +++ +   L     +  +++ EKER   E+ +                  
Sbjct: 658 CVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQL----------------- 700

Query: 220 TYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLV 273
               + +LQ LK  L +  KG  SL+E  R  A +   QQR +  L  + R LV
Sbjct: 701 ----QEQLQALKESL-KVTKG--SLEEEKRRAADALEEQQRCISELKAETRSLV 747


>gi|21361517 UBX domain protein 1 [Homo sapiens]
          Length = 312

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 15/143 (10%)

Query: 67  LGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVH 126
           LGH + +  TS+ +   +      G     E +  ++E E+     R L   A++  E  
Sbjct: 56  LGHILGREPTSSEQGGLEGSGSAAG-----EGKPALSEEERQEQTKRMLELVAQKQRERE 110

Query: 127 QAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAV 186
           +   +E R+ L+R  +   Q  EL+    R+ ++E R       AE+  REK    +A  
Sbjct: 111 E---REEREALERERQRRRQGQELSAARQRLQEDEMRRA-----AEERRREKAEELAARQ 162

Query: 187 RESHEKERTRAERTKNWSLIGSV 209
           R   + ER +AER K +   GSV
Sbjct: 163 RVREKIERDKAERAKKYG--GSV 183


>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
          Length = 1093

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 72/334 (21%), Positives = 130/334 (38%), Gaps = 55/334 (16%)

Query: 94  EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYL----- 148
           E REAQ      EK       L+ EA ++L+    ++KE    +  +  E +Q +     
Sbjct: 459 EKREAQLLSLSKEKA------LLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEK 512

Query: 149 ---------ELATLEHRMLQEEKRLR-----TAYLRAEDSER------EKFSLFSAAVRE 188
                    + A  E + ++EE   R     TA L  E  E+      E   L    +  
Sbjct: 513 KVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHN 572

Query: 189 SHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAI 248
           S+  ++ RA+  +N +++  +   +  +          LQ LK +L   ++     +E I
Sbjct: 573 SNIIKKLRAKDKENENMVAKLNKKVKEL-------EEELQHLKQVLDGKEEVEKQHRENI 625

Query: 249 REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPT------RDRDVDVLSAA 302
           ++  S   RQ++DL  L VD+  L       Q +   A    T        +D +   AA
Sbjct: 626 KKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAA 685

Query: 303 LKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLL 362
           L  ++    ++ + LE  +E+    ++T +   G ++L          E A      +L 
Sbjct: 686 LSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQR-----TEQAAARKEDYLR 740

Query: 363 EQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVT 396
            +      + + +QRL+   NRN   S  V+  T
Sbjct: 741 HE------IGELQQRLQEAENRNQELSQSVSSTT 768


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 53/249 (21%), Positives = 108/249 (43%), Gaps = 32/249 (12%)

Query: 87   EEFVGLN-EVREAQGKVTE-AEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144
            EE  G N ++ E    V +  E+   + + L ++  +  E+HQ  +++  +RL ++++  
Sbjct: 5396 EELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAA 5455

Query: 145  S---QYLELATLEHRMLQEEKRLR--TAYLRAEDSEREKFSLFSAAVRESHEKERTRAER 199
            S   +Y E+  L  + +++ K L   T    +    RE++ L    + ES E +      
Sbjct: 5456 SHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAM 5515

Query: 200  TKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259
            T+    + SV           Y      Q++  L  E ++    L++ I+ +  +     
Sbjct: 5516 TEKLQYLTSV-----------YCTEKMSQQVAELGRETEE----LRQMIKIRLQNLQDAA 5560

Query: 260  RDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEG 319
            +D+     +L+ L  A    Q   +   SP       +V   +LKEQLSH + + S +E 
Sbjct: 5561 KDMKKFEAELKKLQAALEQAQ---ATLTSP-------EVGRLSLKEQLSHRQHLLSEMES 5610

Query: 320  LREQLDGLE 328
            L+ ++  ++
Sbjct: 5611 LKPKVQAVQ 5619



 Score = 33.1 bits (74), Expect = 0.47
 Identities = 52/257 (20%), Positives = 101/257 (39%), Gaps = 34/257 (13%)

Query: 96   REAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEH 155
            R+ Q ++ +A++      GL     E+L     KL+   D L+R      + +++   + 
Sbjct: 1297 RDVQQQIAQAQQG---EGGLPDRGHEELR----KLESTLDGLERSRERQERRIQVTLRKW 1349

Query: 156  RMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIG 215
               +  K     YL    S  E+F  FS+    S E E+T+    +  S+          
Sbjct: 1350 ERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESI---------- 1399

Query: 216  VAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHN-LMVDLRGLVH 274
                     V+ + L     E   GP + ++ +++QA S   Q + L + L  D++ +  
Sbjct: 1400 --------AVQAENLVKEASEIPLGPQN-KQLLQQQAKSIKEQVKKLEDTLEEDIKTMEM 1450

Query: 275  AAGPGQDSGSQAGSPPT----RDRDVDVL---SAALKEQLSHSRQVHSCLEGLREQLDGL 327
                    GS   +       ++++++ L   S+A+  Q+S  +     +E     + GL
Sbjct: 1451 VKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGL 1510

Query: 328  EKTCSQMAGVVQLVKSA 344
            E+     A  V   +SA
Sbjct: 1511 EEEAQSFAQFVTTGESA 1527


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 53/249 (21%), Positives = 108/249 (43%), Gaps = 32/249 (12%)

Query: 87   EEFVGLN-EVREAQGKVTE-AEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144
            EE  G N ++ E    V +  E+   + + L ++  +  E+HQ  +++  +RL ++++  
Sbjct: 5467 EELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAA 5526

Query: 145  S---QYLELATLEHRMLQEEKRLR--TAYLRAEDSEREKFSLFSAAVRESHEKERTRAER 199
            S   +Y E+  L  + +++ K L   T    +    RE++ L    + ES E +      
Sbjct: 5527 SHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAM 5586

Query: 200  TKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259
            T+    + SV           Y      Q++  L  E ++    L++ I+ +  +     
Sbjct: 5587 TEKLQYLTSV-----------YCTEKMSQQVAELGRETEE----LRQMIKIRLQNLQDAA 5631

Query: 260  RDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEG 319
            +D+     +L+ L  A    Q   +   SP       +V   +LKEQLSH + + S +E 
Sbjct: 5632 KDMKKFEAELKKLQAALEQAQ---ATLTSP-------EVGRLSLKEQLSHRQHLLSEMES 5681

Query: 320  LREQLDGLE 328
            L+ ++  ++
Sbjct: 5682 LKPKVQAVQ 5690



 Score = 33.1 bits (74), Expect = 0.47
 Identities = 52/257 (20%), Positives = 101/257 (39%), Gaps = 34/257 (13%)

Query: 96   REAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEH 155
            R+ Q ++ +A++      GL     E+L     KL+   D L+R      + +++   + 
Sbjct: 1290 RDVQQQIAQAQQG---EGGLPDRGHEELR----KLESTLDGLERSRERQERRIQVTLRKW 1342

Query: 156  RMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIG 215
               +  K     YL    S  E+F  FS+    S E E+T+    +  S+          
Sbjct: 1343 ERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESI---------- 1392

Query: 216  VAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHN-LMVDLRGLVH 274
                     V+ + L     E   GP + ++ +++QA S   Q + L + L  D++ +  
Sbjct: 1393 --------AVQAENLVKEASEIPLGPQN-KQLLQQQAKSIKEQVKKLEDTLEEDIKTMEM 1443

Query: 275  AAGPGQDSGSQAGSPPT----RDRDVDVL---SAALKEQLSHSRQVHSCLEGLREQLDGL 327
                    GS   +       ++++++ L   S+A+  Q+S  +     +E     + GL
Sbjct: 1444 VKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGL 1503

Query: 328  EKTCSQMAGVVQLVKSA 344
            E+     A  V   +SA
Sbjct: 1504 EEEAQSFAQFVTTGESA 1520


>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
          Length = 1044

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 48/175 (27%), Positives = 75/175 (42%), Gaps = 30/175 (17%)

Query: 48   RPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNE---------VREA 98
            R +E+ L +H RL A         ++ A S  K   D+YE  +   E           E 
Sbjct: 857  RDKEIELVIH-RLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSEL 915

Query: 99   QGKVTEAEKVFMVARGLVREAREDLEVHQA---KLKEVRDRLDRVSREDSQ--------- 146
            +G++ EAE   +  +GLVR+    LE  QA   +L   R  L +V R++ +         
Sbjct: 916  KGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEE 975

Query: 147  ----YLELATLEHRMLQE----EKRLRTAYLRAEDSEREKFSLFSAAVRESHEKE 193
                  ELATL+ R   E     +R++TA  R E++     +   AAV+ +   E
Sbjct: 976  TRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLE 1030



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 56/276 (20%), Positives = 102/276 (36%), Gaps = 16/276 (5%)

Query: 56   LHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGL 115
            L  +L     ALG   ++RA    +   +   +     ++ E+   +T A       R  
Sbjct: 752  LREQLEREKEALGQQERERARQRQRAELEELRQ-----QLEESSSALTRA------LRAE 800

Query: 116  VREAREDLEV-HQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDS 174
              + RE+ E  HQ +L  ++ +L+ + R+  +       E  +L  E+ LR    +  D 
Sbjct: 801  FEKGREEQERRHQMELNTLKQQLE-LERQAWEAGRTRKEEAWLLNREQELREEIRKGRDK 859

Query: 175  EREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALL 234
            E E       A     ++E  +A  ++   L       L  +  S    + R  ELK  L
Sbjct: 860  EIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQL 919

Query: 235  LEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDR 294
             EA+   + LQ  +R++  +    Q     L  +   L        +    A    TR  
Sbjct: 920  GEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQA 979

Query: 295  DVDVLSAALKEQLSHS---RQVHSCLEGLREQLDGL 327
              ++ +   ++QL      R+V + L    E +  L
Sbjct: 980  KAELATLQARQQLELEEVHRRVKTALARKEEAVSSL 1015


>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
          Length = 1080

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 48/175 (27%), Positives = 75/175 (42%), Gaps = 30/175 (17%)

Query: 48   RPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNE---------VREA 98
            R +E+ L +H RL A         ++ A S  K   D+YE  +   E           E 
Sbjct: 893  RDKEIELVIH-RLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSEL 951

Query: 99   QGKVTEAEKVFMVARGLVREAREDLEVHQA---KLKEVRDRLDRVSREDSQ--------- 146
            +G++ EAE   +  +GLVR+    LE  QA   +L   R  L +V R++ +         
Sbjct: 952  KGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEE 1011

Query: 147  ----YLELATLEHRMLQE----EKRLRTAYLRAEDSEREKFSLFSAAVRESHEKE 193
                  ELATL+ R   E     +R++TA  R E++     +   AAV+ +   E
Sbjct: 1012 TRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLE 1066



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 50/239 (20%), Positives = 91/239 (38%), Gaps = 6/239 (2%)

Query: 94   EVREAQGKVTEAEKVFMVA-RGLVREAREDLEV-HQAKLKEVRDRLDRVSREDSQYLELA 151
            E+ E + ++ E+      A R    + RE+ E  HQ +L  ++ +L+ + R+  +     
Sbjct: 814  ELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLE-LERQAWEAGRTR 872

Query: 152  TLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLG 211
              E  +L  E+ LR    +  D E E       A     ++E  +A  ++   L      
Sbjct: 873  KEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEA 932

Query: 212  ALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRG 271
             L  +  S    + R  ELK  L EA+   + LQ  +R++  +    Q     L  +   
Sbjct: 933  ELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSN 992

Query: 272  LVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHS---RQVHSCLEGLREQLDGL 327
            L        +    A    TR    ++ +   ++QL      R+V + L    E +  L
Sbjct: 993  LAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSL 1051


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 48/205 (23%), Positives = 89/205 (43%), Gaps = 28/205 (13%)

Query: 95  VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRL----DRVSREDSQYLEL 150
           +RE + ++ E E+        +RE  E L   + +L+E  +RL    +R+  ++ +  E 
Sbjct: 271 LREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 330

Query: 151 ATL--EHRMLQEEKRLRTAYLRAEDSER--EKFSLFSAAVRESHEKERTRAERTKNWSLI 206
             L  + R+L+E ++L     R E+ ER  E+  L    V E  E+ER R +  + W   
Sbjct: 331 EKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLE-EVEELLEQERLRQQDERLWQ-- 387

Query: 207 GSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSY---SRQQRDLH 263
                        T     RL+EL+ +L   + G  +L E   E  S +   + + +   
Sbjct: 388 -----------QETLQELERLRELERML---ELGWEALYEQRAEPRSGFEELNNENKSTL 433

Query: 264 NLMVDLRGLVHAAGPGQDSGSQAGS 288
            L   ++ L  + G  +  GS++ +
Sbjct: 434 QLEQQVKELKKSGGAEEPRGSESAA 458



 Score = 37.0 bits (84), Expect = 0.033
 Identities = 59/243 (24%), Positives = 97/243 (39%), Gaps = 32/243 (13%)

Query: 26  LGRDLFMTRTLCSP--GPSQP-GEKRPEEVALGLHH---RLPALGRALGHSIQQRATSTA 79
           LGR LF  +   +    P  P G  + E++    +H    L ++GR L   ++     + 
Sbjct: 133 LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192

Query: 80  KTWWDRYEEFVGLNE--VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRL 137
                R EE +   E  +RE + ++ E E+        +RE  E L   + +L E  +RL
Sbjct: 193 LN--RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERL 250

Query: 138 DRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRA 197
               RE  +   L   E R+ ++E+RLR    R  + E E+       +RE  E+   + 
Sbjct: 251 ----REHEE--RLCEQEERLCEQEERLREQEERLHEQE-ERLCEQEERLREQEERLCEQE 303

Query: 198 ERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSR 257
           ER +                        RL+E +  L E +K P   QE + E+      
Sbjct: 304 ERLREQE-------------ERLCEQEERLREQEERLCEQEKLPG--QERLLEEVEKLLE 348

Query: 258 QQR 260
           Q+R
Sbjct: 349 QER 351


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 52/285 (18%), Positives = 110/285 (38%), Gaps = 50/285 (17%)

Query: 72  QQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLK 131
           +++     K  WD+ E+      +RE + K+ E E+       ++RE  E ++  + K++
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE-------MMREQEEKMQEQEEKMR 591

Query: 132 EVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHE 191
           E  +++        Q  ++   E +M ++E+++       E  E +K       + E  E
Sbjct: 592 EQEEKM------WEQEEKMQEQEEKMWEQEEKM------WEQEEEDKMQEQEEMMWEQEE 639

Query: 192 KERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQ 251
           K + + E  K W                      +++E +  + E ++     +E +REQ
Sbjct: 640 KMQEQEE--KMWE------------------QEEKMREQEEKMREQEEKMQGQEEKMREQ 679

Query: 252 ASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311
                 Q+  +      +RG       GQ+            ++         E      
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMW-GQEEKMWGQEEKMWGQE---------EMREKEE 729

Query: 312 QVHSCLEGLREQLDGLEKTCSQ-MAGVVQLVKSAAHPGLVEPADG 355
           ++    E ++E+L   E+ CS+      +++ + +H G VEPA G
Sbjct: 730 RIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGG 774



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 23/105 (21%), Positives = 51/105 (48%), Gaps = 8/105 (7%)

Query: 95  VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLE 154
           +RE +GK+ E E+        +RE  ++L   + +L+E +   ++  +   Q  ++   E
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323

Query: 155 HRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAER 199
            +M ++E+++     R  + E++        +RE  +K R + ER
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQ--------MREQEQKMRDQEER 360


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform
           4 [Homo sapiens]
          Length = 3321

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 30/223 (13%)

Query: 111 VARGLVREAREDLEVHQAKLKEVRDRLDRVSREDS---QYLELATLEHRMLQEEKRLR-- 165
           + + L ++  +  E+HQ  +++  +RL ++++  S   +Y E+  L  + +++ K L   
Sbjct: 17  LGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHG 76

Query: 166 TAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRV 225
           T    +    RE++ L    + ES E +      T+    + SV           Y    
Sbjct: 77  TIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSV-----------YCTEK 125

Query: 226 RLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQ 285
             Q++  L  E ++    L++ I+ +  +     +D+     +L+ L  A    Q   + 
Sbjct: 126 MSQQVAELGRETEE----LRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQ---AT 178

Query: 286 AGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQLDGLE 328
             SP       +V   +LKEQLSH + + S +E L+ ++  ++
Sbjct: 179 LTSP-------EVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQ 214


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 37.4 bits (85), Expect = 0.025
 Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 6/129 (4%)

Query: 76   TSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRD 135
            +S +K    + EE V L E    +G+  E E+     +  ++E  +   +H+ + +  + 
Sbjct: 1530 SSKSKEQQYKDEEEVTLEEEVSREGE--EKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587

Query: 136  RLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERT 195
            R     +   +  +LA  E ++ QEE++L  AY++    +RE     + A  +  +KE T
Sbjct: 1588 RAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDRE----MAQAEGKFAQKEET 1643

Query: 196  RAERTKNWS 204
             A+R +  S
Sbjct: 1644 LAQRGEKLS 1652



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 19/146 (13%)

Query: 60   LPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREA 119
            LP   + L    ++ A    +  WD  E      E+ + +GK+ E +K        +   
Sbjct: 1700 LPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ 1759

Query: 120  REDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKF 179
            RE L   + KL +  + L +   + +Q+ E      +M +EE+RL           R++ 
Sbjct: 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKE------KMPEEEERL----------GRKRE 1803

Query: 180  SLFSAAVRESHEKER---TRAERTKN 202
             L    ++ + ++ER   +  E TKN
Sbjct: 1804 QLIEKKMKLAQKRERWINSMEELTKN 1829


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 37.4 bits (85), Expect = 0.025
 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 13/159 (8%)

Query: 111 VARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLE------LATLEHRMLQEEKRL 164
           VA+ L ++ R  LE  Q K++++R++L +   E+   L       L++L  R+   +K +
Sbjct: 599 VAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERL---QKAI 655

Query: 165 RTAYLRAEDSEREKFSLFSAAVRESHE--KERTRAERTKNWSLIGSVLGALIGV--AGST 220
                R  + E ++ S   A V+ S +  +++ RAE+  +   +   L +      A   
Sbjct: 656 EEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLE 715

Query: 221 YVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259
             NR  L++LK  +  ++K   +   A +E+A    R+Q
Sbjct: 716 QKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 754


>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
           sapiens]
          Length = 693

 Score = 37.4 bits (85), Expect = 0.025
 Identities = 67/316 (21%), Positives = 124/316 (39%), Gaps = 44/316 (13%)

Query: 73  QRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKE 132
           Q  +  +K    R +E   +   +EAQ +V E E++         E  E L   Q  L+E
Sbjct: 326 QALSLLSKEQKQRLQEQEEMLREQEAQ-RVREQERLC--------EQNERLREQQKTLQE 376

Query: 133 VRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEK 192
             +RL +      Q   L   E R+ +EE+RL+    R  D E   +        E  +K
Sbjct: 377 QGERLRK------QEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWK-----KEERLQK 425

Query: 193 ERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIRE-- 250
           +  R   ++N  L   +             +   L   K   L+ ++    LQE + E  
Sbjct: 426 QEERLALSQNHKLDKQL--------AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEH 477

Query: 251 -QASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSH 309
            +A+S+  QQ +    +V L        PG+  G Q     + + +    +  + E L  
Sbjct: 478 LEAASHQNQQLETQLSLVAL--------PGEGDGGQ--HLDSEEEEAPRPTPNIPEDLES 527

Query: 310 SRQVHSCLEGLREQLDGLEKTCSQMAGVVQ---LVKSAAHPGLVEPADGAMPSFLLEQGS 366
                S ++  +E+ DG E+   +  G VQ   +         V  + GA+P+   ++  
Sbjct: 528 REATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEME 587

Query: 367 MILALSDTEQRLEAQV 382
            ++ L+  E+ ++ ++
Sbjct: 588 DVIRLAQKEEEMKVKL 603


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 37.0 bits (84), Expect = 0.033
 Identities = 37/184 (20%), Positives = 78/184 (42%), Gaps = 21/184 (11%)

Query: 95  VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL---KEVRDRLDRVSREDSQYLE-- 149
           +RE +GK+ E E+        +RE  ++L   + +L   KE+R++ +++  ++ +  E  
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361

Query: 150 ---------LATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERT 200
                    +   E R+ ++EK++R    +  D E   +           EKE    E+ 
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE----QDERLREKEERMREQE 417

Query: 201 KNWSLIGSVL--GALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQ 258
           K W  +  +     +      T     ++QE +  + E +K     +E +REQ     +Q
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQ 476

Query: 259 QRDL 262
           + ++
Sbjct: 477 EENM 480



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 34/161 (21%), Positives = 68/161 (42%), Gaps = 7/161 (4%)

Query: 46  EKRPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNE-VREAQGKVTE 104
           E    E+ L +      L RA     Q +  +  +  W + EE     + +R+ + K+  
Sbjct: 238 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297

Query: 105 AEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRL 164
            E+      G +RE  E +   + +L+E    L    +E  +  EL   E +M ++E+++
Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM 357

Query: 165 --RTAYLRAEDS----EREKFSLFSAAVRESHEKERTRAER 199
             +   +R ++     + E+       +RE  +K R + ER
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 25/138 (18%), Positives = 59/138 (42%), Gaps = 5/138 (3%)

Query: 71  IQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL 130
           ++++     K  WD+ E+      +RE + K+ E E++       ++E  E ++  + K+
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626

Query: 131 KEVRDRLDRVSREDSQYLELATLEHRMLQEEKRL----RTAYLRAEDSEREKFSLFSAAV 186
            E  +++     +  +  E    +   + E++RL       +   +  E+EK       +
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686

Query: 187 RESHEKE-RTRAERTKNW 203
            E  + E +T+ +  K W
Sbjct: 687 WEQEKMEKKTQEQEKKTW 704


>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
          Length = 1146

 Score = 37.0 bits (84), Expect = 0.033
 Identities = 86/337 (25%), Positives = 133/337 (39%), Gaps = 63/337 (18%)

Query: 39   PGPSQPGEKRPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREA 98
            PG ++  EK   E+   +        R L  +++QR    A       E  +G  E  EA
Sbjct: 712  PGAAEASEKLQVELETRI--------RGLEEALRQREREAAA----ELEAALGKCEAAEA 759

Query: 99   QG-----KVTEAEKVFMVA---------RGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144
            +      +V EAE               R  + +AREDL    ++L+E+           
Sbjct: 760  EAGRLRERVREAEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLREL--------EAA 811

Query: 145  SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204
            S  L+ A     + +EE R     LRAE ++RE+     A + +S E E  R +     +
Sbjct: 812  SACLDEARASRLLAEEEAR----GLRAELAQREE-----ARLEQSRELEVLREQLATARA 862

Query: 205  LIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIR--EQASSYSRQQRDL 262
                   A   +  +      R+ EL A   EA++G   L+EA     Q+   + + R L
Sbjct: 863  TGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRL 922

Query: 263  HNLMVDLRGLVHAAGPGQD---SGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSC--- 316
                ++LRG   AA   Q+   +G +A           V S AL E   H R V +    
Sbjct: 923  QEEALELRG--RAASLEQEVVATGKEAARLRAELERERVCSVALSE---HERIVGTLQAN 977

Query: 317  ---LEGLREQLDGL-EKTCSQMAGVVQ---LVKSAAH 346
               LEG  E+L    EKT +++  V +    +KS  H
Sbjct: 978  VAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERH 1014


>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
          Length = 284

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 9/127 (7%)

Query: 84  DRYEEFVG--LNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVS 141
           DR +E +   L ++ EA+    E+E+   V      +  E +E+ + +LKE +   +   
Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 159

Query: 142 REDSQYL-ELATLEHRMLQEEKRLRTAYLRAEDSERE------KFSLFSAAVRESHEKER 194
           R+  +   +L  LE  + + E+R   + L+  D E E            AA  +  EKE 
Sbjct: 160 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 219

Query: 195 TRAERTK 201
              E  K
Sbjct: 220 KYEEEIK 226


>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
          Length = 248

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 9/127 (7%)

Query: 84  DRYEEFVG--LNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVS 141
           DR +E +   L ++ EA+    E+E+   V      +  E +E+ + +LKE +   +   
Sbjct: 64  DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123

Query: 142 REDSQYL-ELATLEHRMLQEEKRLRTAYLRAEDSERE------KFSLFSAAVRESHEKER 194
           R+  +   +L  LE  + + E+R   + L+  D E E            AA  +  EKE 
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 183

Query: 195 TRAERTK 201
              E  K
Sbjct: 184 KYEEEIK 190


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 38/197 (19%), Positives = 80/197 (40%), Gaps = 32/197 (16%)

Query: 83  WDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKE----VRDRLD 138
           W + E+     ++R+ + KV   E+        +RE  E +   + K++E    +R++ +
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537

Query: 139 RVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHE-----KE 193
           ++  ++    E    E +M ++E++++         E+EK       +RE  E     KE
Sbjct: 538 KIREQEEMMQEQ---EEKMGEQEEKMQ---------EQEKMRRQEEKIREQEEKIREQKE 585

Query: 194 RTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQAS 253
           + R +  K W     +                 +QE +  + E ++     +E ++EQ  
Sbjct: 586 KIREQEEKIWEQEEKI-----------REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634

Query: 254 SYSRQQRDLHNLMVDLR 270
              RQ+  +    V LR
Sbjct: 635 KMRRQEEKMWEQEVRLR 651



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 36/183 (19%)

Query: 83  WDRYEEFVGLNEVR-EAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVS 141
           W++ E+   L E+  E + K+ E E+  M  +  +RE +E+    + K++E   R ++ +
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEK-MHEQEKIRE-QEEKRQEEEKIREQEKRQEQEA 416

Query: 142 REDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTK 201
           +   Q  ++   E ++ ++EK++     R E+   E+         E   +E  R E+ +
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKM----WRQEEKIHEQ---------EKIREEEKRQEQEE 463

Query: 202 NWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRD 261
            W                    ++R QE     +  QK  +  QE IR+Q     RQ+  
Sbjct: 464 MWR----------------QEEKIREQEE----IWRQKEKMHEQEKIRKQEEKVWRQEEK 503

Query: 262 LHN 264
           +H+
Sbjct: 504 MHD 506



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 22/129 (17%), Positives = 56/129 (43%), Gaps = 2/129 (1%)

Query: 72  QQRATSTAKTWWDRYEEFVGLNE-VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL 130
           Q++     +  W + E+     E +RE + K+   E+        +RE  E +   +  +
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546

Query: 131 KEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESH 190
           +E  +++     +  +  ++   E ++ ++E+++R    +  + E EK       +RE  
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE-EKIWEQEEKIREQE 605

Query: 191 EKERTRAER 199
           E  + + E+
Sbjct: 606 EMMQEQEEK 614


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 50/201 (24%), Positives = 85/201 (42%), Gaps = 26/201 (12%)

Query: 26  LGRDLFMTRTLCSP--GPSQP-GEKRPEEVALGLHH---RLPALGRALGHSIQQRATSTA 79
           LGR LF  +   +    P  P G  + E++    +H    L ++GR L   ++     + 
Sbjct: 133 LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192

Query: 80  KTWWDRYEEFVGLNEVR---------EAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL 130
                R EE +   E R         E + ++ E E+        +RE  E L   + +L
Sbjct: 193 LN--RRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERL 250

Query: 131 KEVRDRL----DRVSREDSQYLELATL--EHRMLQEEKRLRTAYLRAEDSER--EKFSLF 182
            E  +RL    +R+  ++ +  E   L  + R+L+E ++L     R E+ ER  E+  L 
Sbjct: 251 HEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLL 310

Query: 183 SAAVRESHEKERTRAERTKNW 203
              V E  E+ER R +  + W
Sbjct: 311 DE-VEELLEQERLRQQDERLW 330


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 36/179 (20%), Positives = 75/179 (41%), Gaps = 10/179 (5%)

Query: 94  EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQY-LELAT 152
           E+R+ +  +   E+   V +  +   +E L     +L  ++DR+  +  + S     LAT
Sbjct: 526 EIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALAT 585

Query: 153 LEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHE-KERTRAERTKNWSLIGSVLG 211
           LE  + ++E+ +     + E  +RE+     +  +E+ + KE+  A + +      S++ 
Sbjct: 586 LEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 645

Query: 212 ALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLR 270
                +        R  +LK+L +          E  +E+ S    Q +  HN+  D R
Sbjct: 646 LKEHASSLASAGLKRDSKLKSLEIAI--------EQKKEECSKLEAQLKKAHNIEDDSR 696


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 55/268 (20%), Positives = 102/268 (38%), Gaps = 29/268 (10%)

Query: 118 EAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSERE 177
           E  E L   Q  L+E  +RL +      Q   L   E R+ +EE+RL+    R  D E  
Sbjct: 362 EQNERLREQQKTLQEQGERLRK------QEQRLRKQEERLRKEEERLQKQEKRLWDQEER 415

Query: 178 KFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEA 237
            +        E  +K+  R   ++N  L   +             +   L   K   L+ 
Sbjct: 416 LWK-----KEERLQKQEERLALSQNHKLDKQL--------AEPQCSFEDLNNEKKSALQL 462

Query: 238 QKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVD 297
           ++    LQE + E+    + QQ       + L  L     PG+  G Q     + + +  
Sbjct: 463 EQQVKELQEKLDEEHLEAASQQNQQLETQLSLVAL-----PGEGDGGQ--HLDSEEEEAP 515

Query: 298 VLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQ---LVKSAAHPGLVEPAD 354
             +  + E L       S ++  +E+ DG E+   +  G VQ   +         V  + 
Sbjct: 516 RPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQ 575

Query: 355 GAMPSFLLEQGSMILALSDTEQRLEAQV 382
           GA+P+   ++   ++ L+  E+ ++ ++
Sbjct: 576 GAVPNTRHQEMEDVIRLAQKEEEMKVKL 603


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score = 35.8 bits (81), Expect = 0.073
 Identities = 67/316 (21%), Positives = 123/316 (38%), Gaps = 44/316 (13%)

Query: 73  QRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKE 132
           Q  +  +K    R +E   +   +EAQ +V E E++         E  E L   Q  L+E
Sbjct: 326 QALSLLSKEQKQRLQEQEEMLREQEAQ-RVREQERLC--------EQNERLREQQKTLQE 376

Query: 133 VRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEK 192
             +RL +      Q   L   E R+ +EE+RL+    R  D E   +        E  +K
Sbjct: 377 QGERLRK------QEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWK-----KEERLQK 425

Query: 193 ERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIRE-- 250
           +  R   ++N  L   +             +   L   K   L+ ++    LQE + E  
Sbjct: 426 QEERLALSQNHKLDKQL--------AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEH 477

Query: 251 -QASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSH 309
            +A+S   QQ +    +V L        PG+  G Q     + + +    +  + E L  
Sbjct: 478 LEAASQRNQQLETQLSLVAL--------PGEGDGGQ--HLDSEEEEAPRPTPNIPEDLES 527

Query: 310 SRQVHSCLEGLREQLDGLEKTCSQMAGVVQ---LVKSAAHPGLVEPADGAMPSFLLEQGS 366
                S ++  +E+ DG E+   +  G VQ   +         V  + GA+P+   ++  
Sbjct: 528 REATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEME 587

Query: 367 MILALSDTEQRLEAQV 382
            ++ L+  E+ ++ ++
Sbjct: 588 DVIRLAQKEEEMKVKL 603


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,143,918
Number of Sequences: 37866
Number of extensions: 682934
Number of successful extensions: 3677
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 243
Number of HSP's that attempted gapping in prelim test: 3249
Number of HSP's gapped (non-prelim): 670
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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