BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|94536784 coiled-coil domain containing 51 [Homo sapiens] (411 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|94536784 coiled-coil domain containing 51 [Homo sapiens] 801 0.0 gi|93277096 limbin [Homo sapiens] 44 2e-04 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 44 3e-04 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 44 3e-04 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 44 3e-04 gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 44 3e-04 gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 40 0.005 gi|31542634 filamin A interacting protein 1 [Homo sapiens] 39 0.009 gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 39 0.011 gi|21361517 UBX domain protein 1 [Homo sapiens] 39 0.011 gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 38 0.015 gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 38 0.015 gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 38 0.015 gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 38 0.015 gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 38 0.015 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 38 0.019 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 38 0.019 gi|154277118 spectrin repeat containing, nuclear envelope 1 isof... 38 0.019 gi|221219020 NYD-SP11 protein [Homo sapiens] 37 0.025 gi|115648142 centrosomal protein 164kDa [Homo sapiens] 37 0.025 gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 37 0.025 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.033 gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 37 0.033 gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 36 0.056 gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 36 0.056 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 36 0.056 gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 36 0.056 gi|34577114 cytomatrix protein p110 [Homo sapiens] 36 0.056 gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 36 0.056 gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 36 0.073 >gi|94536784 coiled-coil domain containing 51 [Homo sapiens] Length = 411 Score = 801 bits (2069), Expect = 0.0 Identities = 411/411 (100%), Positives = 411/411 (100%) Query: 1 MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRL 60 MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRL Sbjct: 1 MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRL 60 Query: 61 PALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAR 120 PALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAR Sbjct: 61 PALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAR 120 Query: 121 EDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFS 180 EDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFS Sbjct: 121 EDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFS 180 Query: 181 LFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKG 240 LFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKG Sbjct: 181 LFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKG 240 Query: 241 PVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS 300 PVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS Sbjct: 241 PVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS 300 Query: 301 AALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSF 360 AALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSF Sbjct: 301 AALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSF 360 Query: 361 LLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS 411 LLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS Sbjct: 361 LLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS 411 >gi|93277096 limbin [Homo sapiens] Length = 1308 Score = 44.3 bits (103), Expect = 2e-04 Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 2/107 (1%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153 E R Q V EA + A + + R +E H A L+E+++RLD+ + +D + L L+ Sbjct: 685 EQRREQASVGEAFRTVEDAGQYLHQKRSLMEEHGATLEELQERLDQAALDDLRTLTLSLF 744 Query: 154 EHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKE-RTRAER 199 E + E +RL+ + + E +R LF + E H KE RAE+ Sbjct: 745 E-KATDELRRLQNSAMTQELLKRGVPWLFLQQILEEHGKEMAARAEQ 790 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 43.9 bits (102), Expect = 3e-04 Identities = 71/318 (22%), Positives = 127/318 (39%), Gaps = 37/318 (11%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153 +++E QG+ + E+ A ++ A+ +LE L E + R+S+E S Sbjct: 1285 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1344 Query: 154 EHRMLQEEKRLRTAY---LRAEDSE----REKFSLFSAAVRESHEKERTRAERTKNW-SL 205 +LQEE R + A +RA ++E RE+ +AA + + +T + W Sbjct: 1345 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRR 1404 Query: 206 IGSVLGALIGVAGSTYVNRV---------RLQELKALLLEAQKGPVSLQEAI-------- 248 GAL AG R RL E + ++G LQ+ + Sbjct: 1405 QEEEAGAL--EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1462 Query: 249 --REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS--AALK 304 R+ S+ ++QR L+ + + V A ++ G R+R+ LS AL+ Sbjct: 1463 QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG----REREARALSLTRALE 1518 Query: 305 EQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQ 364 E+ ++ LR +L+ L + + V ++ A + E A + + + E Sbjct: 1519 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR--VAEQAANDLRAQVTEL 1576 Query: 365 GSMILALSDTEQRLEAQV 382 + A D + RLE V Sbjct: 1577 EDELTAAEDAKLRLEVTV 1594 Score = 34.7 bits (78), Expect = 0.16 Identities = 61/249 (24%), Positives = 102/249 (40%), Gaps = 22/249 (8%) Query: 26 LGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHR-LPALGRALGHSIQQRATSTAKTWWD 84 L ++L T E+ ++ALG R + A L +++ A + + + Sbjct: 1331 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1390 Query: 85 RYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144 L+E R Q + A + AR E L A+ E DRL+R R Sbjct: 1391 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1450 Query: 145 SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF-----SAAVRESHEKERTRAER 199 Q L+ AT++ L+++++L + + ++ KF +A +R E+ER AE Sbjct: 1451 QQELDDATMD---LEQQRQL----VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG 1503 Query: 200 TKNWSLIGSVLGALIGVAGS----TYVNRVRLQELKALLL---EAQKGPVSLQEAIR--E 250 + + S+ AL + NR EL+ALL + K L+ A R E Sbjct: 1504 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAE 1563 Query: 251 QASSYSRQQ 259 QA++ R Q Sbjct: 1564 QAANDLRAQ 1572 Score = 31.6 bits (70), Expect = 1.4 Identities = 64/311 (20%), Positives = 111/311 (35%), Gaps = 56/311 (18%) Query: 115 LVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELA------------TLEHRMLQ--- 159 L + E+ +H+A ++E+R R + E ++ LE A LE + + Sbjct: 1204 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1263 Query: 160 EEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKN----WSLIGSVLGALIG 215 E L+TA E R + + ER RAE + + + +V GAL Sbjct: 1264 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1323 Query: 216 VAGSTYVNRVRLQELKALLLEAQK---------------------GPVSLQEAIREQASS 254 T L +A L +AQ+ L+E + E+A++ Sbjct: 1324 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAA 1383 Query: 255 YSRQQRDLHNLMVDL---RGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311 R R+L L R ++G +A R+ + AL ++L+ Sbjct: 1384 RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE------ALTQRLAEKT 1437 Query: 312 QVHSCLE-GLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILA 370 + LE G R L+ + QLV + +E L E+ + +L Sbjct: 1438 ETVDRLERGRRRLQQELDDATMDLEQQRQLVST------LEKKQRKFDQLLAEEKAAVLR 1491 Query: 371 LSDTEQRLEAQ 381 + +R EA+ Sbjct: 1492 AVEERERAEAE 1502 Score = 30.8 bits (68), Expect = 2.3 Identities = 45/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%) Query: 92 LNEVREAQGKVTEAEKVF---MVARGLVREAREDL-EVHQAKLKEVRDRLDRVSRED--- 144 L +REAQ + EA++ VAR + R DL E +A E+ D LD + + Sbjct: 1135 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1194 Query: 145 SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204 S+ + T + L+EE R+ A A R++ + E E+ R + Sbjct: 1195 SKREQEVTELKKTLEEETRIHEA---AVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251 Query: 205 L-----IGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259 L + + L + + R + L+ L E Q + A E A R Q Sbjct: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311 Query: 260 RDLHNL 265 +L N+ Sbjct: 1312 AELENV 1317 Score = 30.0 bits (66), Expect = 4.0 Identities = 62/277 (22%), Positives = 104/277 (37%), Gaps = 52/277 (18%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153 EV E QG+V + E+ L + R + E+ A+ +E R RL +R+ L ++ L Sbjct: 899 EVGELQGRVAQLEEE---RARLAEQLRAEAELC-AEAEETRGRL--AARKQELELVVSEL 952 Query: 154 EHRMLQEE----------KRLRT------AYLRAEDSEREKFSLFSAAVRESHEK----- 192 E R+ +EE KRL+ A+L AE+ R+K L +K Sbjct: 953 EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1012 Query: 193 ---ERTRAERTKNWSLIGSVLGALIGVAGS-----TYVNRVRLQ------ELKALLLEAQ 238 E ++ +K L+ L A +N++RL+ +++ L + + Sbjct: 1013 LLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEE 1072 Query: 239 KGPVSLQEAIRE---QASSYSRQQRDLHNLMVDLRG--------LVHAAGPGQDSGSQAG 287 KG L++ R ++S Q + +LR L A +D G Sbjct: 1073 KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARA 1132 Query: 288 SPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQL 324 R+ A +E L R + E R L Sbjct: 1133 QLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1169 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 43.9 bits (102), Expect = 3e-04 Identities = 71/318 (22%), Positives = 127/318 (39%), Gaps = 37/318 (11%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153 +++E QG+ + E+ A ++ A+ +LE L E + R+S+E S Sbjct: 1277 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1336 Query: 154 EHRMLQEEKRLRTAY---LRAEDSE----REKFSLFSAAVRESHEKERTRAERTKNW-SL 205 +LQEE R + A +RA ++E RE+ +AA + + +T + W Sbjct: 1337 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRR 1396 Query: 206 IGSVLGALIGVAGSTYVNRV---------RLQELKALLLEAQKGPVSLQEAI-------- 248 GAL AG R RL E + ++G LQ+ + Sbjct: 1397 QEEEAGAL--EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1454 Query: 249 --REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS--AALK 304 R+ S+ ++QR L+ + + V A ++ G R+R+ LS AL+ Sbjct: 1455 QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG----REREARALSLTRALE 1510 Query: 305 EQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQ 364 E+ ++ LR +L+ L + + V ++ A + E A + + + E Sbjct: 1511 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR--VAEQAANDLRAQVTEL 1568 Query: 365 GSMILALSDTEQRLEAQV 382 + A D + RLE V Sbjct: 1569 EDELTAAEDAKLRLEVTV 1586 Score = 34.7 bits (78), Expect = 0.16 Identities = 61/249 (24%), Positives = 102/249 (40%), Gaps = 22/249 (8%) Query: 26 LGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHR-LPALGRALGHSIQQRATSTAKTWWD 84 L ++L T E+ ++ALG R + A L +++ A + + + Sbjct: 1323 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1382 Query: 85 RYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144 L+E R Q + A + AR E L A+ E DRL+R R Sbjct: 1383 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1442 Query: 145 SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF-----SAAVRESHEKERTRAER 199 Q L+ AT++ L+++++L + + ++ KF +A +R E+ER AE Sbjct: 1443 QQELDDATMD---LEQQRQL----VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG 1495 Query: 200 TKNWSLIGSVLGALIGVAGS----TYVNRVRLQELKALLL---EAQKGPVSLQEAIR--E 250 + + S+ AL + NR EL+ALL + K L+ A R E Sbjct: 1496 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAE 1555 Query: 251 QASSYSRQQ 259 QA++ R Q Sbjct: 1556 QAANDLRAQ 1564 Score = 31.6 bits (70), Expect = 1.4 Identities = 64/311 (20%), Positives = 111/311 (35%), Gaps = 56/311 (18%) Query: 115 LVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELA------------TLEHRMLQ--- 159 L + E+ +H+A ++E+R R + E ++ LE A LE + + Sbjct: 1196 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1255 Query: 160 EEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKN----WSLIGSVLGALIG 215 E L+TA E R + + ER RAE + + + +V GAL Sbjct: 1256 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1315 Query: 216 VAGSTYVNRVRLQELKALLLEAQK---------------------GPVSLQEAIREQASS 254 T L +A L +AQ+ L+E + E+A++ Sbjct: 1316 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAA 1375 Query: 255 YSRQQRDLHNLMVDL---RGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311 R R+L L R ++G +A R+ + AL ++L+ Sbjct: 1376 RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE------ALTQRLAEKT 1429 Query: 312 QVHSCLE-GLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILA 370 + LE G R L+ + QLV + +E L E+ + +L Sbjct: 1430 ETVDRLERGRRRLQQELDDATMDLEQQRQLVST------LEKKQRKFDQLLAEEKAAVLR 1483 Query: 371 LSDTEQRLEAQ 381 + +R EA+ Sbjct: 1484 AVEERERAEAE 1494 Score = 30.8 bits (68), Expect = 2.3 Identities = 45/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%) Query: 92 LNEVREAQGKVTEAEKVF---MVARGLVREAREDL-EVHQAKLKEVRDRLDRVSRED--- 144 L +REAQ + EA++ VAR + R DL E +A E+ D LD + + Sbjct: 1127 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1186 Query: 145 SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204 S+ + T + L+EE R+ A A R++ + E E+ R + Sbjct: 1187 SKREQEVTELKKTLEEETRIHEA---AVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 Query: 205 L-----IGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259 L + + L + + R + L+ L E Q + A E A R Q Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 Query: 260 RDLHNL 265 +L N+ Sbjct: 1304 AELENV 1309 Score = 30.0 bits (66), Expect = 4.0 Identities = 62/277 (22%), Positives = 104/277 (37%), Gaps = 52/277 (18%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153 EV E QG+V + E+ L + R + E+ A+ +E R RL +R+ L ++ L Sbjct: 891 EVGELQGRVAQLEEE---RARLAEQLRAEAELC-AEAEETRGRL--AARKQELELVVSEL 944 Query: 154 EHRMLQEE----------KRLRT------AYLRAEDSEREKFSLFSAAVRESHEK----- 192 E R+ +EE KRL+ A+L AE+ R+K L +K Sbjct: 945 EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1004 Query: 193 ---ERTRAERTKNWSLIGSVLGALIGVAGS-----TYVNRVRLQ------ELKALLLEAQ 238 E ++ +K L+ L A +N++RL+ +++ L + + Sbjct: 1005 LLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEE 1064 Query: 239 KGPVSLQEAIRE---QASSYSRQQRDLHNLMVDLRG--------LVHAAGPGQDSGSQAG 287 KG L++ R ++S Q + +LR L A +D G Sbjct: 1065 KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARA 1124 Query: 288 SPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQL 324 R+ A +E L R + E R L Sbjct: 1125 QLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1161 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 43.9 bits (102), Expect = 3e-04 Identities = 71/318 (22%), Positives = 127/318 (39%), Gaps = 37/318 (11%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153 +++E QG+ + E+ A ++ A+ +LE L E + R+S+E S Sbjct: 1318 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1377 Query: 154 EHRMLQEEKRLRTAY---LRAEDSE----REKFSLFSAAVRESHEKERTRAERTKNW-SL 205 +LQEE R + A +RA ++E RE+ +AA + + +T + W Sbjct: 1378 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRR 1437 Query: 206 IGSVLGALIGVAGSTYVNRV---------RLQELKALLLEAQKGPVSLQEAI-------- 248 GAL AG R RL E + ++G LQ+ + Sbjct: 1438 QEEEAGAL--EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1495 Query: 249 --REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS--AALK 304 R+ S+ ++QR L+ + + V A ++ G R+R+ LS AL+ Sbjct: 1496 QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG----REREARALSLTRALE 1551 Query: 305 EQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQ 364 E+ ++ LR +L+ L + + V ++ A + E A + + + E Sbjct: 1552 EEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR--VAEQAANDLRAQVTEL 1609 Query: 365 GSMILALSDTEQRLEAQV 382 + A D + RLE V Sbjct: 1610 EDELTAAEDAKLRLEVTV 1627 Score = 34.7 bits (78), Expect = 0.16 Identities = 61/249 (24%), Positives = 102/249 (40%), Gaps = 22/249 (8%) Query: 26 LGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHR-LPALGRALGHSIQQRATSTAKTWWD 84 L ++L T E+ ++ALG R + A L +++ A + + + Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423 Query: 85 RYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144 L+E R Q + A + AR E L A+ E DRL+R R Sbjct: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483 Query: 145 SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF-----SAAVRESHEKERTRAER 199 Q L+ AT++ L+++++L + + ++ KF +A +R E+ER AE Sbjct: 1484 QQELDDATMD---LEQQRQL----VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEG 1536 Query: 200 TKNWSLIGSVLGALIGVAGS----TYVNRVRLQELKALLL---EAQKGPVSLQEAIR--E 250 + + S+ AL + NR EL+ALL + K L+ A R E Sbjct: 1537 REREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAE 1596 Query: 251 QASSYSRQQ 259 QA++ R Q Sbjct: 1597 QAANDLRAQ 1605 Score = 31.6 bits (70), Expect = 1.4 Identities = 64/311 (20%), Positives = 111/311 (35%), Gaps = 56/311 (18%) Query: 115 LVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELA------------TLEHRMLQ--- 159 L + E+ +H+A ++E+R R + E ++ LE A LE + + Sbjct: 1237 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296 Query: 160 EEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKN----WSLIGSVLGALIG 215 E L+TA E R + + ER RAE + + + +V GAL Sbjct: 1297 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1356 Query: 216 VAGSTYVNRVRLQELKALLLEAQK---------------------GPVSLQEAIREQASS 254 T L +A L +AQ+ L+E + E+A++ Sbjct: 1357 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAA 1416 Query: 255 YSRQQRDLHNLMVDL---RGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311 R R+L L R ++G +A R+ + AL ++L+ Sbjct: 1417 RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE------ALTQRLAEKT 1470 Query: 312 QVHSCLE-GLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILA 370 + LE G R L+ + QLV + +E L E+ + +L Sbjct: 1471 ETVDRLERGRRRLQQELDDATMDLEQQRQLVST------LEKKQRKFDQLLAEEKAAVLR 1524 Query: 371 LSDTEQRLEAQ 381 + +R EA+ Sbjct: 1525 AVEERERAEAE 1535 Score = 30.8 bits (68), Expect = 2.3 Identities = 45/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%) Query: 92 LNEVREAQGKVTEAEKVF---MVARGLVREAREDL-EVHQAKLKEVRDRLDRVSRED--- 144 L +REAQ + EA++ VAR + R DL E +A E+ D LD + + Sbjct: 1168 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1227 Query: 145 SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204 S+ + T + L+EE R+ A A R++ + E E+ R + Sbjct: 1228 SKREQEVTELKKTLEEETRIHEA---AVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284 Query: 205 L-----IGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259 L + + L + + R + L+ L E Q + A E A R Q Sbjct: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344 Query: 260 RDLHNL 265 +L N+ Sbjct: 1345 AELENV 1350 Score = 30.0 bits (66), Expect = 4.0 Identities = 62/277 (22%), Positives = 104/277 (37%), Gaps = 52/277 (18%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATL 153 EV E QG+V + E+ L + R + E+ A+ +E R RL +R+ L ++ L Sbjct: 932 EVGELQGRVAQLEEE---RARLAEQLRAEAELC-AEAEETRGRL--AARKQELELVVSEL 985 Query: 154 EHRMLQEE----------KRLRT------AYLRAEDSEREKFSLFSAAVRESHEK----- 192 E R+ +EE KRL+ A+L AE+ R+K L +K Sbjct: 986 EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1045 Query: 193 ---ERTRAERTKNWSLIGSVLGALIGVAGS-----TYVNRVRLQ------ELKALLLEAQ 238 E ++ +K L+ L A +N++RL+ +++ L + + Sbjct: 1046 LLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEE 1105 Query: 239 KGPVSLQEAIRE---QASSYSRQQRDLHNLMVDLRG--------LVHAAGPGQDSGSQAG 287 KG L++ R ++S Q + +LR L A +D G Sbjct: 1106 KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARA 1165 Query: 288 SPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQL 324 R+ A +E L R + E R L Sbjct: 1166 QLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1202 >gi|210032790 hypothetical protein LOC27146 [Homo sapiens] Length = 1060 Score = 43.9 bits (102), Expect = 3e-04 Identities = 60/284 (21%), Positives = 108/284 (38%), Gaps = 45/284 (15%) Query: 120 REDLEVHQAKLKEVRDRLDRVSREDSQY-----LELATLEHRMLQEEKRLRTAYLRAEDS 174 REDL+ + R++L R +E +Q +L R L+ ++ R L+A + Sbjct: 624 REDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEE 683 Query: 175 EREKFSLFSAAVR-ESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKAL 233 +K S S ++ ++H E E L R R+Q +AL Sbjct: 684 RLKKESSHSLQIQHQTHRLELQALEEKARQEL---------------QEERERMQAQQAL 728 Query: 234 LLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSG---------- 283 LLE SL++ + EQ ++ S Q+DL L +LR L Q G Sbjct: 729 LLE------SLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATE 782 Query: 284 -----SQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVV 338 QAGSPP L E+ + Q+ + LR +++ ++ ++ Sbjct: 783 ERGGPGQAGSPPGAAGQGSGEGCGLWEE---NAQLQDAVRRLRAEVEQHQQEAQKLRDQR 839 Query: 339 QLVKSAAHPGLVEPADGAMPSFLLEQGSMILALSDTEQRLEAQV 382 + ++ + E +M+ S + +L+A++ Sbjct: 840 RFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARL 883 Score = 35.0 bits (79), Expect = 0.12 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Query: 116 VREAREDLEVHQAKLKEVRD--RLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAED 173 VR R ++E HQ + +++RD R +++ + E+ TL +E + + + A+ Sbjct: 818 VRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQA 877 Query: 174 SEREKFSLFSAAVRESHEKERTRAERTKNWSLIG 207 + + + A +++S EK A R ++ LIG Sbjct: 878 QLQARLAALEAELKDSGEKPGKGASRPEDLQLIG 911 >gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens] Length = 1478 Score = 39.7 bits (91), Expect = 0.005 Identities = 71/307 (23%), Positives = 117/307 (38%), Gaps = 55/307 (17%) Query: 50 EEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGL---NEVREAQGKVTEAE 106 +++A H L RAL QQ+ ++ ++ VG NE RE ++ ++ Sbjct: 720 QQLAEARHREL----RALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQ 775 Query: 107 KVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHR-MLQEEKRLR 165 V +G V+ + + QAK++ D D+V + S E EH+ ++Q+ K Sbjct: 776 AQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSM-AEAVLREHKTLVQQLKEQN 834 Query: 166 TAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRV 225 A RA E + S A++E E + E Sbjct: 835 EALNRAHVQELLQCSEREGALQEERADEAQQRE--------------------------- 867 Query: 226 RLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQ 285 +EL+AL E + S +EA E A Q LH D L G Q Sbjct: 868 --EELRALQEELSQAKCSSEEAQLEHA----ELQEQLHRANTDTAEL----------GIQ 911 Query: 286 AGSPPTRDRDVDVLSAALKEQLSHSRQVHSC-LEGLREQLDGLEKTCSQMAGVVQLVKSA 344 + V+ A ++L +++ S EGL Q+ GL++ + ++ K+A Sbjct: 912 VCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAA 971 Query: 345 AH--PGL 349 A PGL Sbjct: 972 AGSLPGL 978 Score = 30.4 bits (67), Expect = 3.0 Identities = 60/264 (22%), Positives = 111/264 (42%), Gaps = 32/264 (12%) Query: 118 EAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQ-EEKRLRTAYLRAEDSER 176 E R +L+ + + K++R+R+ ++ RE+ + + + LQ E +R RTA AED+ R Sbjct: 234 EMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGRTA---AEDNVR 290 Query: 177 EKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLE 236 L + E T+A + L + G +G A L+ L+++ Sbjct: 291 ----LTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESM--- 343 Query: 237 AQKGPVSLQEAIRE-QASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRD 295 LQ +E +A+ S +++ H + G + A D+ S T+ R Sbjct: 344 -------LQPLAQELEATRDSLDKKNQH--LASFPGWLAMAQQKADTASD-----TKGRQ 389 Query: 296 VDVLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADG 355 + S A +E ++ + LE R +++ + + Q A + QLVK L E A Sbjct: 390 EPIPSDAAQEMQELGEKLQA-LERERTKVEEVNR--QQSAQLEQLVKELQ---LKEDARA 443 Query: 356 AMPSFLLEQGSMILALSDTEQRLE 379 ++ + E + LS Q + Sbjct: 444 SLERLVKEMAPLQEELSGKGQEAD 467 >gi|31542634 filamin A interacting protein 1 [Homo sapiens] Length = 1213 Score = 38.9 bits (89), Expect = 0.009 Identities = 64/257 (24%), Positives = 104/257 (40%), Gaps = 37/257 (14%) Query: 94 EVREAQGKVTEAEKVFMVARG---LVREAREDLEVHQAKLKEVRDRLDRVSREDS----Q 146 EV EA E EKV V L +E +V++ + E+ DRL+ +E + Sbjct: 109 EVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISEL-DRLEEKQKETYRRMLE 167 Query: 147 YLELATLEHRM----LQEEKRLRTAYLRAEDS-----EREKFSLFSAAVRESHEKERTRA 197 L LA HR L+ EK T Y+ D E+E+ L +E + R Sbjct: 168 QLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEK 227 Query: 198 ERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSY-- 255 E K + + L L A + R ++ L L++QK L + +RE+ Sbjct: 228 ENAKRLNKLRDELVKLKSFA--LMLVDERQMHIEQLGLQSQKVQ-DLTQKLREEEEKLKA 284 Query: 256 --SRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQV 313 S+ + D L+ H A ++ + ++A L Q SH+RQ+ Sbjct: 285 ITSKSKEDRQKLLKLEVDFEHKAS-------------RFSQEHEEMNAKLANQESHNRQL 331 Query: 314 HSCLEGLREQLDGLEKT 330 L GL ++++ LE+T Sbjct: 332 RLKLVGLTQRIEELEET 348 Score = 35.4 bits (80), Expect = 0.095 Identities = 49/248 (19%), Positives = 105/248 (42%), Gaps = 24/248 (9%) Query: 92 LNEVREAQGKVTEAEKVFMV------ARGLVREAREDLEVHQAKLKEVRDRLDRVSREDS 145 L + RE K+ E EK + A+ L + E +++ L V +R + + Sbjct: 204 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 263 Query: 146 QYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLF----SAAVRESHEKERTRAERTK 201 Q ++ L ++ +EE++L+ ++++ ++ L A R S E E A+ Sbjct: 264 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 323 Query: 202 NWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRD 261 S + L+G+ R++EL+ E K +E ++E ++ + Sbjct: 324 QESHNRQLRLKLVGLTQ-------RIEELE----ETNKNLQKAEEELQELRDKIAKGECG 372 Query: 262 LHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLR 321 +LM ++ L + + ++ R+ L L+E+ HS+++ +E L+ Sbjct: 373 NSSLMAEVENLRKRVLEMEGKDEEITKTESQCRE---LRKKLQEEEHHSKELRLEVEKLQ 429 Query: 322 EQLDGLEK 329 +++ LEK Sbjct: 430 KRMSELEK 437 >gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] Length = 2115 Score = 38.5 bits (88), Expect = 0.011 Identities = 54/234 (23%), Positives = 93/234 (39%), Gaps = 33/234 (14%) Query: 47 KRPEEVALGLHHRLPALGRALGHSIQQRATSTAK---TWWDRYEEFVGLNEVREAQGKVT 103 ++ E+ + GL H++ L +L QQ K T D ++ E REA + Sbjct: 540 QQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREAS--LR 597 Query: 104 EAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQ-YLELATLEHRMLQEEK 162 E + L +E LE+ Q +L+ + D +Q E A L ++ + + Sbjct: 598 ERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQA 657 Query: 163 RLRTAYLRAEDSEREKFSL---FSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGS 219 + TA +++ + L + +++ EKER E+ + Sbjct: 658 CVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQL----------------- 700 Query: 220 TYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLV 273 + +LQ LK L + KG SL+E R A + QQR + L + R LV Sbjct: 701 ----QEQLQALKESL-KVTKG--SLEEEKRRAADALEEQQRCISELKAETRSLV 747 >gi|21361517 UBX domain protein 1 [Homo sapiens] Length = 312 Score = 38.5 bits (88), Expect = 0.011 Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 15/143 (10%) Query: 67 LGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVH 126 LGH + + TS+ + + G E + ++E E+ R L A++ E Sbjct: 56 LGHILGREPTSSEQGGLEGSGSAAG-----EGKPALSEEERQEQTKRMLELVAQKQRERE 110 Query: 127 QAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAV 186 + +E R+ L+R + Q EL+ R+ ++E R AE+ REK +A Sbjct: 111 E---REEREALERERQRRRQGQELSAARQRLQEDEMRRA-----AEERRREKAEELAARQ 162 Query: 187 RESHEKERTRAERTKNWSLIGSV 209 R + ER +AER K + GSV Sbjct: 163 RVREKIERDKAERAKKYG--GSV 183 >gi|110347443 TATA element modulatory factor 1 [Homo sapiens] Length = 1093 Score = 38.1 bits (87), Expect = 0.015 Identities = 72/334 (21%), Positives = 130/334 (38%), Gaps = 55/334 (16%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYL----- 148 E REAQ EK L+ EA ++L+ ++KE + + E +Q + Sbjct: 459 EKREAQLLSLSKEKA------LLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEK 512 Query: 149 ---------ELATLEHRMLQEEKRLR-----TAYLRAEDSER------EKFSLFSAAVRE 188 + A E + ++EE R TA L E E+ E L + Sbjct: 513 KVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHN 572 Query: 189 SHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAI 248 S+ ++ RA+ +N +++ + + + LQ LK +L ++ +E I Sbjct: 573 SNIIKKLRAKDKENENMVAKLNKKVKEL-------EEELQHLKQVLDGKEEVEKQHRENI 625 Query: 249 REQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPT------RDRDVDVLSAA 302 ++ S RQ++DL L VD+ L Q + A T +D + AA Sbjct: 626 KKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAA 685 Query: 303 LKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLL 362 L ++ ++ + LE +E+ ++T + G ++L E A +L Sbjct: 686 LSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQR-----TEQAAARKEDYLR 740 Query: 363 EQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVT 396 + + + +QRL+ NRN S V+ T Sbjct: 741 HE------IGELQQRLQEAENRNQELSQSVSSTT 768 >gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2 [Homo sapiens] Length = 8749 Score = 38.1 bits (87), Expect = 0.015 Identities = 53/249 (21%), Positives = 108/249 (43%), Gaps = 32/249 (12%) Query: 87 EEFVGLN-EVREAQGKVTE-AEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144 EE G N ++ E V + E+ + + L ++ + E+HQ +++ +RL ++++ Sbjct: 5396 EELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAA 5455 Query: 145 S---QYLELATLEHRMLQEEKRLR--TAYLRAEDSEREKFSLFSAAVRESHEKERTRAER 199 S +Y E+ L + +++ K L T + RE++ L + ES E + Sbjct: 5456 SHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAM 5515 Query: 200 TKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259 T+ + SV Y Q++ L E ++ L++ I+ + + Sbjct: 5516 TEKLQYLTSV-----------YCTEKMSQQVAELGRETEE----LRQMIKIRLQNLQDAA 5560 Query: 260 RDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEG 319 +D+ +L+ L A Q + SP +V +LKEQLSH + + S +E Sbjct: 5561 KDMKKFEAELKKLQAALEQAQ---ATLTSP-------EVGRLSLKEQLSHRQHLLSEMES 5610 Query: 320 LREQLDGLE 328 L+ ++ ++ Sbjct: 5611 LKPKVQAVQ 5619 Score = 33.1 bits (74), Expect = 0.47 Identities = 52/257 (20%), Positives = 101/257 (39%), Gaps = 34/257 (13%) Query: 96 REAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEH 155 R+ Q ++ +A++ GL E+L KL+ D L+R + +++ + Sbjct: 1297 RDVQQQIAQAQQG---EGGLPDRGHEELR----KLESTLDGLERSRERQERRIQVTLRKW 1349 Query: 156 RMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIG 215 + K YL S E+F FS+ S E E+T+ + S+ Sbjct: 1350 ERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESI---------- 1399 Query: 216 VAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHN-LMVDLRGLVH 274 V+ + L E GP + ++ +++QA S Q + L + L D++ + Sbjct: 1400 --------AVQAENLVKEASEIPLGPQN-KQLLQQQAKSIKEQVKKLEDTLEEDIKTMEM 1450 Query: 275 AAGPGQDSGSQAGSPPT----RDRDVDVL---SAALKEQLSHSRQVHSCLEGLREQLDGL 327 GS + ++++++ L S+A+ Q+S + +E + GL Sbjct: 1451 VKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGL 1510 Query: 328 EKTCSQMAGVVQLVKSA 344 E+ A V +SA Sbjct: 1511 EEEAQSFAQFVTTGESA 1527 >gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1 [Homo sapiens] Length = 8797 Score = 38.1 bits (87), Expect = 0.015 Identities = 53/249 (21%), Positives = 108/249 (43%), Gaps = 32/249 (12%) Query: 87 EEFVGLN-EVREAQGKVTE-AEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144 EE G N ++ E V + E+ + + L ++ + E+HQ +++ +RL ++++ Sbjct: 5467 EELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAA 5526 Query: 145 S---QYLELATLEHRMLQEEKRLR--TAYLRAEDSEREKFSLFSAAVRESHEKERTRAER 199 S +Y E+ L + +++ K L T + RE++ L + ES E + Sbjct: 5527 SHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAM 5586 Query: 200 TKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259 T+ + SV Y Q++ L E ++ L++ I+ + + Sbjct: 5587 TEKLQYLTSV-----------YCTEKMSQQVAELGRETEE----LRQMIKIRLQNLQDAA 5631 Query: 260 RDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEG 319 +D+ +L+ L A Q + SP +V +LKEQLSH + + S +E Sbjct: 5632 KDMKKFEAELKKLQAALEQAQ---ATLTSP-------EVGRLSLKEQLSHRQHLLSEMES 5681 Query: 320 LREQLDGLE 328 L+ ++ ++ Sbjct: 5682 LKPKVQAVQ 5690 Score = 33.1 bits (74), Expect = 0.47 Identities = 52/257 (20%), Positives = 101/257 (39%), Gaps = 34/257 (13%) Query: 96 REAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEH 155 R+ Q ++ +A++ GL E+L KL+ D L+R + +++ + Sbjct: 1290 RDVQQQIAQAQQG---EGGLPDRGHEELR----KLESTLDGLERSRERQERRIQVTLRKW 1342 Query: 156 RMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIG 215 + K YL S E+F FS+ S E E+T+ + S+ Sbjct: 1343 ERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESI---------- 1392 Query: 216 VAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHN-LMVDLRGLVH 274 V+ + L E GP + ++ +++QA S Q + L + L D++ + Sbjct: 1393 --------AVQAENLVKEASEIPLGPQN-KQLLQQQAKSIKEQVKKLEDTLEEDIKTMEM 1443 Query: 275 AAGPGQDSGSQAGSPPT----RDRDVDVL---SAALKEQLSHSRQVHSCLEGLREQLDGL 327 GS + ++++++ L S+A+ Q+S + +E + GL Sbjct: 1444 VKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGL 1503 Query: 328 EKTCSQMAGVVQLVKSA 344 E+ A V +SA Sbjct: 1504 EEEAQSFAQFVTTGESA 1520 >gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] Length = 1044 Score = 38.1 bits (87), Expect = 0.015 Identities = 48/175 (27%), Positives = 75/175 (42%), Gaps = 30/175 (17%) Query: 48 RPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNE---------VREA 98 R +E+ L +H RL A ++ A S K D+YE + E E Sbjct: 857 RDKEIELVIH-RLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSEL 915 Query: 99 QGKVTEAEKVFMVARGLVREAREDLEVHQA---KLKEVRDRLDRVSREDSQ--------- 146 +G++ EAE + +GLVR+ LE QA +L R L +V R++ + Sbjct: 916 KGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEE 975 Query: 147 ----YLELATLEHRMLQE----EKRLRTAYLRAEDSEREKFSLFSAAVRESHEKE 193 ELATL+ R E +R++TA R E++ + AAV+ + E Sbjct: 976 TRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLE 1030 Score = 30.8 bits (68), Expect = 2.3 Identities = 56/276 (20%), Positives = 102/276 (36%), Gaps = 16/276 (5%) Query: 56 LHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGL 115 L +L ALG ++RA + + + ++ E+ +T A R Sbjct: 752 LREQLEREKEALGQQERERARQRQRAELEELRQ-----QLEESSSALTRA------LRAE 800 Query: 116 VREAREDLEV-HQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDS 174 + RE+ E HQ +L ++ +L+ + R+ + E +L E+ LR + D Sbjct: 801 FEKGREEQERRHQMELNTLKQQLE-LERQAWEAGRTRKEEAWLLNREQELREEIRKGRDK 859 Query: 175 EREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALL 234 E E A ++E +A ++ L L + S + R ELK L Sbjct: 860 EIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQL 919 Query: 235 LEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDR 294 EA+ + LQ +R++ + Q L + L + A TR Sbjct: 920 GEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQA 979 Query: 295 DVDVLSAALKEQLSHS---RQVHSCLEGLREQLDGL 327 ++ + ++QL R+V + L E + L Sbjct: 980 KAELATLQARQQLELEEVHRRVKTALARKEEAVSSL 1015 >gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] Length = 1080 Score = 38.1 bits (87), Expect = 0.015 Identities = 48/175 (27%), Positives = 75/175 (42%), Gaps = 30/175 (17%) Query: 48 RPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNE---------VREA 98 R +E+ L +H RL A ++ A S K D+YE + E E Sbjct: 893 RDKEIELVIH-RLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSEL 951 Query: 99 QGKVTEAEKVFMVARGLVREAREDLEVHQA---KLKEVRDRLDRVSREDSQ--------- 146 +G++ EAE + +GLVR+ LE QA +L R L +V R++ + Sbjct: 952 KGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEE 1011 Query: 147 ----YLELATLEHRMLQE----EKRLRTAYLRAEDSEREKFSLFSAAVRESHEKE 193 ELATL+ R E +R++TA R E++ + AAV+ + E Sbjct: 1012 TRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLE 1066 Score = 30.0 bits (66), Expect = 4.0 Identities = 50/239 (20%), Positives = 91/239 (38%), Gaps = 6/239 (2%) Query: 94 EVREAQGKVTEAEKVFMVA-RGLVREAREDLEV-HQAKLKEVRDRLDRVSREDSQYLELA 151 E+ E + ++ E+ A R + RE+ E HQ +L ++ +L+ + R+ + Sbjct: 814 ELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLE-LERQAWEAGRTR 872 Query: 152 TLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLG 211 E +L E+ LR + D E E A ++E +A ++ L Sbjct: 873 KEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEA 932 Query: 212 ALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRG 271 L + S + R ELK L EA+ + LQ +R++ + Q L + Sbjct: 933 ELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSN 992 Query: 272 LVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHS---RQVHSCLEGLREQLDGL 327 L + A TR ++ + ++QL R+V + L E + L Sbjct: 993 LAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEVHRRVKTALARKEEAVSSL 1051 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 37.7 bits (86), Expect = 0.019 Identities = 48/205 (23%), Positives = 89/205 (43%), Gaps = 28/205 (13%) Query: 95 VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRL----DRVSREDSQYLEL 150 +RE + ++ E E+ +RE E L + +L+E +RL +R+ ++ + E Sbjct: 271 LREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 330 Query: 151 ATL--EHRMLQEEKRLRTAYLRAEDSER--EKFSLFSAAVRESHEKERTRAERTKNWSLI 206 L + R+L+E ++L R E+ ER E+ L V E E+ER R + + W Sbjct: 331 EKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLE-EVEELLEQERLRQQDERLWQ-- 387 Query: 207 GSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSY---SRQQRDLH 263 T RL+EL+ +L + G +L E E S + + + + Sbjct: 388 -----------QETLQELERLRELERML---ELGWEALYEQRAEPRSGFEELNNENKSTL 433 Query: 264 NLMVDLRGLVHAAGPGQDSGSQAGS 288 L ++ L + G + GS++ + Sbjct: 434 QLEQQVKELKKSGGAEEPRGSESAA 458 Score = 37.0 bits (84), Expect = 0.033 Identities = 59/243 (24%), Positives = 97/243 (39%), Gaps = 32/243 (13%) Query: 26 LGRDLFMTRTLCSP--GPSQP-GEKRPEEVALGLHH---RLPALGRALGHSIQQRATSTA 79 LGR LF + + P P G + E++ +H L ++GR L ++ + Sbjct: 133 LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192 Query: 80 KTWWDRYEEFVGLNE--VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRL 137 R EE + E +RE + ++ E E+ +RE E L + +L E +RL Sbjct: 193 LN--RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERL 250 Query: 138 DRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRA 197 RE + L E R+ ++E+RLR R + E E+ +RE E+ + Sbjct: 251 ----REHEE--RLCEQEERLCEQEERLREQEERLHEQE-ERLCEQEERLREQEERLCEQE 303 Query: 198 ERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSR 257 ER + RL+E + L E +K P QE + E+ Sbjct: 304 ERLREQE-------------ERLCEQEERLREQEERLCEQEKLPG--QERLLEEVEKLLE 348 Query: 258 QQR 260 Q+R Sbjct: 349 QER 351 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 37.7 bits (86), Expect = 0.019 Identities = 52/285 (18%), Positives = 110/285 (38%), Gaps = 50/285 (17%) Query: 72 QQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLK 131 +++ K WD+ E+ +RE + K+ E E+ ++RE E ++ + K++ Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE-------MMREQEEKMQEQEEKMR 591 Query: 132 EVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHE 191 E +++ Q ++ E +M ++E+++ E E +K + E E Sbjct: 592 EQEEKM------WEQEEKMQEQEEKMWEQEEKM------WEQEEEDKMQEQEEMMWEQEE 639 Query: 192 KERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQ 251 K + + E K W +++E + + E ++ +E +REQ Sbjct: 640 KMQEQEE--KMWE------------------QEEKMREQEEKMREQEEKMQGQEEKMREQ 679 Query: 252 ASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSR 311 Q+ + +RG GQ+ ++ E Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMW-GQEEKMWGQEEKMWGQE---------EMREKEE 729 Query: 312 QVHSCLEGLREQLDGLEKTCSQ-MAGVVQLVKSAAHPGLVEPADG 355 ++ E ++E+L E+ CS+ +++ + +H G VEPA G Sbjct: 730 RIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGG 774 Score = 35.0 bits (79), Expect = 0.12 Identities = 23/105 (21%), Positives = 51/105 (48%), Gaps = 8/105 (7%) Query: 95 VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLE 154 +RE +GK+ E E+ +RE ++L + +L+E + ++ + Q ++ E Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323 Query: 155 HRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAER 199 +M ++E+++ R + E++ +RE +K R + ER Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQ--------MREQEQKMRDQEER 360 >gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform 4 [Homo sapiens] Length = 3321 Score = 37.7 bits (86), Expect = 0.019 Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 30/223 (13%) Query: 111 VARGLVREAREDLEVHQAKLKEVRDRLDRVSREDS---QYLELATLEHRMLQEEKRLR-- 165 + + L ++ + E+HQ +++ +RL ++++ S +Y E+ L + +++ K L Sbjct: 17 LGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHG 76 Query: 166 TAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRV 225 T + RE++ L + ES E + T+ + SV Y Sbjct: 77 TIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSV-----------YCTEK 125 Query: 226 RLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQ 285 Q++ L E ++ L++ I+ + + +D+ +L+ L A Q + Sbjct: 126 MSQQVAELGRETEE----LRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQ---AT 178 Query: 286 AGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQLDGLE 328 SP +V +LKEQLSH + + S +E L+ ++ ++ Sbjct: 179 LTSP-------EVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQ 214 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 37.4 bits (85), Expect = 0.025 Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 6/129 (4%) Query: 76 TSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRD 135 +S +K + EE V L E +G+ E E+ + ++E + +H+ + + + Sbjct: 1530 SSKSKEQQYKDEEEVTLEEEVSREGE--EKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587 Query: 136 RLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERT 195 R + + +LA E ++ QEE++L AY++ +RE + A + +KE T Sbjct: 1588 RAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDRE----MAQAEGKFAQKEET 1643 Query: 196 RAERTKNWS 204 A+R + S Sbjct: 1644 LAQRGEKLS 1652 Score = 30.0 bits (66), Expect = 4.0 Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 19/146 (13%) Query: 60 LPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREA 119 LP + L ++ A + WD E E+ + +GK+ E +K + Sbjct: 1700 LPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ 1759 Query: 120 REDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKF 179 RE L + KL + + L + + +Q+ E +M +EE+RL R++ Sbjct: 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKE------KMPEEEERL----------GRKRE 1803 Query: 180 SLFSAAVRESHEKER---TRAERTKN 202 L ++ + ++ER + E TKN Sbjct: 1804 QLIEKKMKLAQKRERWINSMEELTKN 1829 >gi|115648142 centrosomal protein 164kDa [Homo sapiens] Length = 1460 Score = 37.4 bits (85), Expect = 0.025 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 13/159 (8%) Query: 111 VARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLE------LATLEHRMLQEEKRL 164 VA+ L ++ R LE Q K++++R++L + E+ L L++L R+ +K + Sbjct: 599 VAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERL---QKAI 655 Query: 165 RTAYLRAEDSEREKFSLFSAAVRESHE--KERTRAERTKNWSLIGSVLGALIGV--AGST 220 R + E ++ S A V+ S + +++ RAE+ + + L + A Sbjct: 656 EEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLE 715 Query: 221 YVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQ 259 NR L++LK + ++K + A +E+A R+Q Sbjct: 716 QKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQ 754 >gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapiens] Length = 693 Score = 37.4 bits (85), Expect = 0.025 Identities = 67/316 (21%), Positives = 124/316 (39%), Gaps = 44/316 (13%) Query: 73 QRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKE 132 Q + +K R +E + +EAQ +V E E++ E E L Q L+E Sbjct: 326 QALSLLSKEQKQRLQEQEEMLREQEAQ-RVREQERLC--------EQNERLREQQKTLQE 376 Query: 133 VRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEK 192 +RL + Q L E R+ +EE+RL+ R D E + E +K Sbjct: 377 QGERLRK------QEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWK-----KEERLQK 425 Query: 193 ERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIRE-- 250 + R ++N L + + L K L+ ++ LQE + E Sbjct: 426 QEERLALSQNHKLDKQL--------AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEH 477 Query: 251 -QASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSH 309 +A+S+ QQ + +V L PG+ G Q + + + + + E L Sbjct: 478 LEAASHQNQQLETQLSLVAL--------PGEGDGGQ--HLDSEEEEAPRPTPNIPEDLES 527 Query: 310 SRQVHSCLEGLREQLDGLEKTCSQMAGVVQ---LVKSAAHPGLVEPADGAMPSFLLEQGS 366 S ++ +E+ DG E+ + G VQ + V + GA+P+ ++ Sbjct: 528 REATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEME 587 Query: 367 MILALSDTEQRLEAQV 382 ++ L+ E+ ++ ++ Sbjct: 588 DVIRLAQKEEEMKVKL 603 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 37.0 bits (84), Expect = 0.033 Identities = 37/184 (20%), Positives = 78/184 (42%), Gaps = 21/184 (11%) Query: 95 VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL---KEVRDRLDRVSREDSQYLE-- 149 +RE +GK+ E E+ +RE ++L + +L KE+R++ +++ ++ + E Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361 Query: 150 ---------LATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERT 200 + E R+ ++EK++R + D E + EKE E+ Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE----QDERLREKEERMREQE 417 Query: 201 KNWSLIGSVL--GALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQ 258 K W + + + T ++QE + + E +K +E +REQ +Q Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQ 476 Query: 259 QRDL 262 + ++ Sbjct: 477 EENM 480 Score = 35.0 bits (79), Expect = 0.12 Identities = 34/161 (21%), Positives = 68/161 (42%), Gaps = 7/161 (4%) Query: 46 EKRPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNE-VREAQGKVTE 104 E E+ L + L RA Q + + + W + EE + +R+ + K+ Sbjct: 238 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297 Query: 105 AEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRL 164 E+ G +RE E + + +L+E L +E + EL E +M ++E+++ Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM 357 Query: 165 --RTAYLRAEDS----EREKFSLFSAAVRESHEKERTRAER 199 + +R ++ + E+ +RE +K R + ER Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398 Score = 34.7 bits (78), Expect = 0.16 Identities = 25/138 (18%), Positives = 59/138 (42%), Gaps = 5/138 (3%) Query: 71 IQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL 130 ++++ K WD+ E+ +RE + K+ E E++ ++E E ++ + K+ Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626 Query: 131 KEVRDRLDRVSREDSQYLELATLEHRMLQEEKRL----RTAYLRAEDSEREKFSLFSAAV 186 E +++ + + E + + E++RL + + E+EK + Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686 Query: 187 RESHEKE-RTRAERTKNW 203 E + E +T+ + K W Sbjct: 687 WEQEKMEKKTQEQEKKTW 704 >gi|126723390 ankyrin repeat domain 24 [Homo sapiens] Length = 1146 Score = 37.0 bits (84), Expect = 0.033 Identities = 86/337 (25%), Positives = 133/337 (39%), Gaps = 63/337 (18%) Query: 39 PGPSQPGEKRPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREA 98 PG ++ EK E+ + R L +++QR A E +G E EA Sbjct: 712 PGAAEASEKLQVELETRI--------RGLEEALRQREREAAA----ELEAALGKCEAAEA 759 Query: 99 QG-----KVTEAEKVFMVA---------RGLVREAREDLEVHQAKLKEVRDRLDRVSRED 144 + +V EAE R + +AREDL ++L+E+ Sbjct: 760 EAGRLRERVREAEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLREL--------EAA 811 Query: 145 SQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWS 204 S L+ A + +EE R LRAE ++RE+ A + +S E E R + + Sbjct: 812 SACLDEARASRLLAEEEAR----GLRAELAQREE-----ARLEQSRELEVLREQLATARA 862 Query: 205 LIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIR--EQASSYSRQQRDL 262 A + + R+ EL A EA++G L+EA Q+ + + R L Sbjct: 863 TGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRL 922 Query: 263 HNLMVDLRGLVHAAGPGQD---SGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSC--- 316 ++LRG AA Q+ +G +A V S AL E H R V + Sbjct: 923 QEEALELRG--RAASLEQEVVATGKEAARLRAELERERVCSVALSE---HERIVGTLQAN 977 Query: 317 ---LEGLREQLDGL-EKTCSQMAGVVQ---LVKSAAH 346 LEG E+L EKT +++ V + +KS H Sbjct: 978 VAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERH 1014 >gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] Length = 284 Score = 36.2 bits (82), Expect = 0.056 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 9/127 (7%) Query: 84 DRYEEFVG--LNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVS 141 DR +E + L ++ EA+ E+E+ V + E +E+ + +LKE + + Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 159 Query: 142 REDSQYL-ELATLEHRMLQEEKRLRTAYLRAEDSERE------KFSLFSAAVRESHEKER 194 R+ + +L LE + + E+R + L+ D E E AA + EKE Sbjct: 160 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 219 Query: 195 TRAERTK 201 E K Sbjct: 220 KYEEEIK 226 >gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] Length = 248 Score = 36.2 bits (82), Expect = 0.056 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 9/127 (7%) Query: 84 DRYEEFVG--LNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVS 141 DR +E + L ++ EA+ E+E+ V + E +E+ + +LKE + + Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123 Query: 142 REDSQYL-ELATLEHRMLQEEKRLRTAYLRAEDSERE------KFSLFSAAVRESHEKER 194 R+ + +L LE + + E+R + L+ D E E AA + EKE Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 183 Query: 195 TRAERTK 201 E K Sbjct: 184 KYEEEIK 190 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 36.2 bits (82), Expect = 0.056 Identities = 38/197 (19%), Positives = 80/197 (40%), Gaps = 32/197 (16%) Query: 83 WDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKE----VRDRLD 138 W + E+ ++R+ + KV E+ +RE E + + K++E +R++ + Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537 Query: 139 RVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHE-----KE 193 ++ ++ E E +M ++E++++ E+EK +RE E KE Sbjct: 538 KIREQEEMMQEQ---EEKMGEQEEKMQ---------EQEKMRRQEEKIREQEEKIREQKE 585 Query: 194 RTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQAS 253 + R + K W + +QE + + E ++ +E ++EQ Sbjct: 586 KIREQEEKIWEQEEKI-----------REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634 Query: 254 SYSRQQRDLHNLMVDLR 270 RQ+ + V LR Sbjct: 635 KMRRQEEKMWEQEVRLR 651 Score = 31.6 bits (70), Expect = 1.4 Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 36/183 (19%) Query: 83 WDRYEEFVGLNEVR-EAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVS 141 W++ E+ L E+ E + K+ E E+ M + +RE +E+ + K++E R ++ + Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEK-MHEQEKIRE-QEEKRQEEEKIREQEKRQEQEA 416 Query: 142 REDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTK 201 + Q ++ E ++ ++EK++ R E+ E+ E +E R E+ + Sbjct: 417 KMWRQEEKIREQEEKIREQEKKM----WRQEEKIHEQ---------EKIREEEKRQEQEE 463 Query: 202 NWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRD 261 W ++R QE + QK + QE IR+Q RQ+ Sbjct: 464 MWR----------------QEEKIREQEE----IWRQKEKMHEQEKIRKQEEKVWRQEEK 503 Query: 262 LHN 264 +H+ Sbjct: 504 MHD 506 Score = 31.2 bits (69), Expect = 1.8 Identities = 22/129 (17%), Positives = 56/129 (43%), Gaps = 2/129 (1%) Query: 72 QQRATSTAKTWWDRYEEFVGLNE-VREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL 130 Q++ + W + E+ E +RE + K+ E+ +RE E + + + Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546 Query: 131 KEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESH 190 +E +++ + + ++ E ++ ++E+++R + + E EK +RE Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE-EKIWEQEEKIREQE 605 Query: 191 EKERTRAER 199 E + + E+ Sbjct: 606 EMMQEQEEK 614 >gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 479 Score = 36.2 bits (82), Expect = 0.056 Identities = 50/201 (24%), Positives = 85/201 (42%), Gaps = 26/201 (12%) Query: 26 LGRDLFMTRTLCSP--GPSQP-GEKRPEEVALGLHH---RLPALGRALGHSIQQRATSTA 79 LGR LF + + P P G + E++ +H L ++GR L ++ + Sbjct: 133 LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192 Query: 80 KTWWDRYEEFVGLNEVR---------EAQGKVTEAEKVFMVARGLVREAREDLEVHQAKL 130 R EE + E R E + ++ E E+ +RE E L + +L Sbjct: 193 LN--RRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERL 250 Query: 131 KEVRDRL----DRVSREDSQYLELATL--EHRMLQEEKRLRTAYLRAEDSER--EKFSLF 182 E +RL +R+ ++ + E L + R+L+E ++L R E+ ER E+ L Sbjct: 251 HEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLL 310 Query: 183 SAAVRESHEKERTRAERTKNW 203 V E E+ER R + + W Sbjct: 311 DE-VEELLEQERLRQQDERLW 330 >gi|34577114 cytomatrix protein p110 [Homo sapiens] Length = 957 Score = 36.2 bits (82), Expect = 0.056 Identities = 36/179 (20%), Positives = 75/179 (41%), Gaps = 10/179 (5%) Query: 94 EVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQY-LELAT 152 E+R+ + + E+ V + + +E L +L ++DR+ + + S LAT Sbjct: 526 EIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALAT 585 Query: 153 LEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHE-KERTRAERTKNWSLIGSVLG 211 LE + ++E+ + + E +RE+ + +E+ + KE+ A + + S++ Sbjct: 586 LEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 645 Query: 212 ALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLR 270 + R +LK+L + E +E+ S Q + HN+ D R Sbjct: 646 LKEHASSLASAGLKRDSKLKSLEIAI--------EQKKEECSKLEAQLKKAHNIEDDSR 696 >gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapiens] Length = 693 Score = 36.2 bits (82), Expect = 0.056 Identities = 55/268 (20%), Positives = 102/268 (38%), Gaps = 29/268 (10%) Query: 118 EAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSERE 177 E E L Q L+E +RL + Q L E R+ +EE+RL+ R D E Sbjct: 362 EQNERLREQQKTLQEQGERLRK------QEQRLRKQEERLRKEEERLQKQEKRLWDQEER 415 Query: 178 KFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEA 237 + E +K+ R ++N L + + L K L+ Sbjct: 416 LWK-----KEERLQKQEERLALSQNHKLDKQL--------AEPQCSFEDLNNEKKSALQL 462 Query: 238 QKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVD 297 ++ LQE + E+ + QQ + L L PG+ G Q + + + Sbjct: 463 EQQVKELQEKLDEEHLEAASQQNQQLETQLSLVAL-----PGEGDGGQ--HLDSEEEEAP 515 Query: 298 VLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQ---LVKSAAHPGLVEPAD 354 + + E L S ++ +E+ DG E+ + G VQ + V + Sbjct: 516 RPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQ 575 Query: 355 GAMPSFLLEQGSMILALSDTEQRLEAQV 382 GA+P+ ++ ++ L+ E+ ++ ++ Sbjct: 576 GAVPNTRHQEMEDVIRLAQKEEEMKVKL 603 >gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sapiens] Length = 693 Score = 35.8 bits (81), Expect = 0.073 Identities = 67/316 (21%), Positives = 123/316 (38%), Gaps = 44/316 (13%) Query: 73 QRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKE 132 Q + +K R +E + +EAQ +V E E++ E E L Q L+E Sbjct: 326 QALSLLSKEQKQRLQEQEEMLREQEAQ-RVREQERLC--------EQNERLREQQKTLQE 376 Query: 133 VRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEK 192 +RL + Q L E R+ +EE+RL+ R D E + E +K Sbjct: 377 QGERLRK------QEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWK-----KEERLQK 425 Query: 193 ERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIRE-- 250 + R ++N L + + L K L+ ++ LQE + E Sbjct: 426 QEERLALSQNHKLDKQL--------AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEH 477 Query: 251 -QASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSH 309 +A+S QQ + +V L PG+ G Q + + + + + E L Sbjct: 478 LEAASQRNQQLETQLSLVAL--------PGEGDGGQ--HLDSEEEEAPRPTPNIPEDLES 527 Query: 310 SRQVHSCLEGLREQLDGLEKTCSQMAGVVQ---LVKSAAHPGLVEPADGAMPSFLLEQGS 366 S ++ +E+ DG E+ + G VQ + V + GA+P+ ++ Sbjct: 528 REATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEME 587 Query: 367 MILALSDTEQRLEAQV 382 ++ L+ E+ ++ ++ Sbjct: 588 DVIRLAQKEEEMKVKL 603 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.131 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,143,918 Number of Sequences: 37866 Number of extensions: 682934 Number of successful extensions: 3677 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 19 Number of HSP's successfully gapped in prelim test: 243 Number of HSP's that attempted gapping in prelim test: 3249 Number of HSP's gapped (non-prelim): 670 length of query: 411 length of database: 18,247,518 effective HSP length: 105 effective length of query: 306 effective length of database: 14,271,588 effective search space: 4367105928 effective search space used: 4367105928 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.