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Search of human proteins with 93204871
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93204871 netrin 4 [Homo sapiens]
(628 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93204871 netrin 4 [Homo sapiens] 1377 0.0
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 366 e-101
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 358 8e-99
gi|143770880 laminin, beta 4 [Homo sapiens] 351 1e-96
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 305 6e-83
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 305 6e-83
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 305 6e-83
gi|148613884 netrin 1 [Homo sapiens] 297 2e-80
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 245 8e-65
gi|21264602 laminin alpha 5 [Homo sapiens] 242 9e-64
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 239 6e-63
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 239 6e-63
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 234 1e-61
gi|5453810 netrin 3 [Homo sapiens] 228 2e-59
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 209 6e-54
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 209 6e-54
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 205 1e-52
gi|219842266 usherin isoform B [Homo sapiens] 197 3e-50
gi|219842259 usherin isoform A [Homo sapiens] 197 3e-50
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 187 2e-47
gi|190014607 netrin G2 [Homo sapiens] 162 9e-40
gi|24308065 netrin 5 [Homo sapiens] 161 2e-39
gi|164414437 netrin G1 isoform 2 [Homo sapiens] 120 3e-27
gi|54312078 netrin G1 isoform 3 [Homo sapiens] 120 3e-27
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 105 2e-22
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 105 2e-22
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 102 8e-22
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 102 8e-22
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 102 1e-21
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 102 1e-21
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 1377 bits (3563), Expect = 0.0
Identities = 628/628 (100%), Positives = 628/628 (100%)
Query: 1 MGSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNATEL 60
MGSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNATEL
Sbjct: 1 MGSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNATEL 60
Query: 61 YCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLD 120
YCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLD
Sbjct: 61 YCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLD 120
Query: 121 LEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAI 180
LEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAI
Sbjct: 121 LEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAI 180
Query: 181 CTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
CTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND
Sbjct: 181 CTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
Query: 241 LNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTA 300
LNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTA
Sbjct: 241 LNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTA 300
Query: 301 GSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCD 360
GSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCD
Sbjct: 301 GSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCD 360
Query: 361 DCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC 420
DCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC
Sbjct: 361 DCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC 420
Query: 421 PCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRP 480
PCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRP
Sbjct: 421 PCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRP 480
Query: 481 VHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGT 540
VHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGT
Sbjct: 481 VHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGT 540
Query: 541 HVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILNPGLEYLVAGHEDIRTGKL 600
HVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILNPGLEYLVAGHEDIRTGKL
Sbjct: 541 HVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILNPGLEYLVAGHEDIRTGKL 600
Query: 601 IVNMKSFVQHWKPSLGRKVMDILKRECK 628
IVNMKSFVQHWKPSLGRKVMDILKRECK
Sbjct: 601 IVNMKSFVQHWKPSLGRKVMDILKRECK 628
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 366 bits (940), Expect = e-101
Identities = 203/524 (38%), Positives = 281/524 (53%), Gaps = 58/524 (11%)
Query: 31 EKACNPRMGNLALGR--KLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPH-- 86
E +C P G+L +GR KL +TCG + E YC S + KC CN+ P+
Sbjct: 32 EGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQE----DKKCFICNSQDPYHE 87
Query: 87 --------LAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMFKSPR 138
+ ++ + A + + WWQS V IQLDLEAEF+FTHLI+ FK+ R
Sbjct: 88 TLNPDSHLIENVVTTFAPNRLKI---WWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFR 144
Query: 139 PAAMVLDRSQDFGKTWKPYKYFATNCSATF-GLEDDVVKK--GAICTSKYSSPFPCTGGE 195
PAAM+++RS DFGKTW Y+YFA +C A+F G+ +KK IC S+YS P T GE
Sbjct: 145 PAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGE 204
Query: 196 VIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQHFTHYAIYD 255
VIF+AL P + E+PYS ++Q LKITNLR++ +K + D E + +YA+YD
Sbjct: 205 VIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYD 264
Query: 256 FIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRP 315
+V+G+CFC GHA +C PV GF + G MVHG CMC+HNT G +C+ C Y+D P
Sbjct: 265 MVVRGNCFCYGHASECAPVDGFNE-EVEG---MVHGHCMCRHNTKGLNCELCMDFYHDLP 320
Query: 316 WEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCK 375
W A+G+ N C+ C CN H+ +CHFD+ V+ A+GN SGGVCDDCQHNT G+ C++CK
Sbjct: 321 WRPAEGRNS--NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCK 378
Query: 376 PGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSN--------GDCPCKPGVA 427
P +Y+ R P+ C+ C+C P GS + CD G C CK V
Sbjct: 379 PFYYQHPERDIRDPNFCERCTCDPAGS-----QNEGICDSYTDFSTGLIAGQCRCKLNVE 433
Query: 428 GRRCDRCMVGYWGFGD---YGCRPCDC--------AGSCDPITGDCISSHTDIDWYHE-- 474
G CD C G++ +GC+ C C CD TG C + +
Sbjct: 434 GEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQC 493
Query: 475 VPDFRPVHNKSEPA----WEWEDAQGFSALLHSGKCECKEQTLG 514
+P+ + N + + A S SG+C C+ +G
Sbjct: 494 LPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIG 537
Score = 101 bits (252), Expect = 2e-21
Identities = 48/113 (42%), Positives = 61/113 (53%), Gaps = 18/113 (15%)
Query: 355 SGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCD 414
+GG C C+ N G+ C RC PG + P CKPC CH GS FC+
Sbjct: 788 NGGQCQ-CRPNVVGRTCNRCAPGTFG------FGPSGCKPCECHLQGSVN------AFCN 834
Query: 415 PSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG---SCDPITGDCIS 464
P G C C GV R+CDRC+ G+WGF C+PC C G CDP+TG+C++
Sbjct: 835 PVTGQCHCFQGVYARQCDRCLPGHWGFP--SCQPCQCNGHADDCDPVTGECLN 885
Score = 100 bits (248), Expect = 5e-21
Identities = 71/258 (27%), Positives = 95/258 (36%), Gaps = 78/258 (30%)
Query: 262 CFCNGHADQCIPVHG--------------------------------FRPVKAPG----- 284
C CNGHAD C PV G RP P
Sbjct: 867 CQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSG 926
Query: 285 ------------TFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTC 332
T + C+C GS C CA Y P E C+ C
Sbjct: 927 RQFARSCYQDPVTLQLA---CVCDPGYIGSRCDDCASGYFGNPSEVG-------GSCQPC 976
Query: 333 KCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDAC 392
+C+ + DT + ++ G C C ++TEG++CQ C+ G+Y D + C
Sbjct: 977 QCHNNIDTTD------PEACDKETGRCLKCLYHTEGEHCQFCRFGYYGD-----ALQQDC 1025
Query: 393 KPCSCHPVGSAVLPAN-SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD-YGCRPCD 450
+ C C+ +G+ N S CD + G C C P V G+ CDRC W GC PC+
Sbjct: 1026 RKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCN 1085
Query: 451 C------AGSCDPITGDC 462
C SC+ TG C
Sbjct: 1086 CNAAHSFGPSCNEFTGQC 1103
Score = 93.2 bits (230), Expect = 6e-19
Identities = 57/181 (31%), Positives = 75/181 (41%), Gaps = 31/181 (17%)
Query: 291 GKCM-CKHNTAGSHCQHCA-PLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 348
G+C+ C ++T G HCQ C Y D +CR C CN + T N
Sbjct: 995 GRCLKCLYHTEGEHCQFCRFGYYGD----------ALQQDCRKCVCN-YLGTVQEHCNGS 1043
Query: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
+ +++ G C C N GQ C RC P ++ ++ C PC+C+ S N
Sbjct: 1044 DCQCDKATGQCL-CLPNVIGQNCDRCAPNTWQ-----LASGTGCDPCNCNAAHSFGPSCN 1097
Query: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC------AGSCDPITGDC 462
T G C C PG GR C C +WG D CR CDC CD TG C
Sbjct: 1098 EFT------GQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQC 1151
Query: 463 I 463
+
Sbjct: 1152 V 1152
Score = 92.0 bits (227), Expect = 1e-18
Identities = 61/195 (31%), Positives = 78/195 (40%), Gaps = 40/195 (20%)
Query: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 348
V G+C C C C P G G P+ C+ C+CNGHAD C
Sbjct: 836 VTGQCHCFQGVYARQCDRCLP-----------GHWGFPS-CQPCQCNGHADDC------- 876
Query: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
+ G C +CQ T G C+RC G+Y D + D C+PC C +
Sbjct: 877 ----DPVTGECLNCQDYTMGHNCERCLAGYYGD--PIIGSGDHCRPCPCPDGPDSGRQFA 930
Query: 409 SVTFCDPSNGD--CPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDCAG--------SC 455
+ DP C C PG G RCD C GY+G C+PC C +C
Sbjct: 931 RSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEAC 990
Query: 456 DPITGDCISS--HTD 468
D TG C+ HT+
Sbjct: 991 DKETGRCLKCLYHTE 1005
Score = 81.3 bits (199), Expect = 3e-15
Identities = 56/161 (34%), Positives = 67/161 (41%), Gaps = 35/161 (21%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C+C N G +C CAP W+ A G TG C C CN + +
Sbjct: 1052 GQCLCLPNVIGQNCDRCAP----NTWQLASG-TG----CDPCNCNA--------AHSFGP 1094
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA-CKPCSCHPVGSAVLPANS 409
S N G C C G+ C C+ F+ D PD C+ C C P G
Sbjct: 1095 SCNEFTGQCQ-CMPGFGGRTCSECQELFWGD-------PDVECRACDCDPRGI------E 1140
Query: 410 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG-FGDYGCRPC 449
CD S G C C GV G RCD+C GY G F D C PC
Sbjct: 1141 TPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD--CTPC 1179
Score = 76.6 bits (187), Expect = 6e-14
Identities = 34/74 (45%), Positives = 43/74 (58%), Gaps = 12/74 (16%)
Query: 395 CSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC--A 452
C C P GS + CDP+ G C C+P V GR C+RC G +GFG GC+PC+C
Sbjct: 773 CECDPQGSLS------SVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 826
Query: 453 GS----CDPITGDC 462
GS C+P+TG C
Sbjct: 827 GSVNAFCNPVTGQC 840
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 358 bits (919), Expect = 8e-99
Identities = 198/488 (40%), Positives = 268/488 (54%), Gaps = 51/488 (10%)
Query: 7 LLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGR--KLWADTTCGQNATELYCFY 64
LL + T+ A V G S +C P G+L +GR +L A +TCG N + YC
Sbjct: 23 LLSVLAATLAQAPAPDVPGCS---RGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCIV 79
Query: 65 SENTDLTCRQPKCDKCNAAYP-------HLAHLPSAMADSSFRFPRTWWQSAEDVHREKI 117
S D + KC C++ P H + + + + + WWQS + I
Sbjct: 80 SHLQD----EKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTI 135
Query: 118 QLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATF-GLE----- 171
QLDLEAEF+FTHLI+ FK+ RPAAM+++RS DFG+TW Y+YF+ +C A F G+
Sbjct: 136 QLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPR 195
Query: 172 --DDVVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLL 229
DDVV C S+YS P T GEVI++ L P +PYS+++Q LKITNLRV L
Sbjct: 196 HWDDVV-----CESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLT 250
Query: 230 KRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMV 289
+ + D E + +YA+Y+ +V+G+CFC GHA +C P G P A G MV
Sbjct: 251 RLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPG-APAHAEG---MV 306
Query: 290 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE 349
HG C+CKHNT G +C+ C Y D PW A+ G + CR C+C+GH +CHFD+ V+
Sbjct: 307 HGACICKHNTRGLNCEQCQDFYRDLPWRPAED--GHSHACRKCECHGHTHSCHFDMAVYL 364
Query: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
ASGN SGGVCD CQHNT G++C+ C+P FYRD + P C+ C C P+GS
Sbjct: 365 ASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQD-GGRC 423
Query: 410 VTFCDPS----NGDCPCKPGVAGRRCDRCMVGYWGFG---DYGCRPCDC--------AGS 454
+ DP+ +G C CK V G RC +C G++G GCR C C +
Sbjct: 424 DSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP 483
Query: 455 CDPITGDC 462
CDP +G C
Sbjct: 484 CDPNSGSC 491
Score = 111 bits (277), Expect = 2e-24
Identities = 75/264 (28%), Positives = 100/264 (37%), Gaps = 89/264 (33%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CNGHAD+C + G C+ C+ +T G HC+ C ++ P
Sbjct: 877 CVCNGHADEC---------------NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
Query: 321 GKTGAPNECRTCKC-------NGHADTCHFD----------------------------- 344
G +CR C C A +CH D
Sbjct: 922 G------QCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGD 975
Query: 345 -------VNVWEASGNRSG----------GVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
+ E SGN G C C H+TEG +C CKPGF+ R
Sbjct: 976 PSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAAR--- 1032
Query: 388 APDACKPCSCHPVGS--AVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF-GDY 444
+C C+C+ +G+ P+ CDPS+G CPC P V G CDRC +W +
Sbjct: 1033 --QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGH 1090
Query: 445 GCRPCDCAGS------CDPITGDC 462
GC+PC C S C+ TG C
Sbjct: 1091 GCQPCACHPSRARGPTCNEFTGQC 1114
Score = 103 bits (258), Expect = 4e-22
Identities = 71/237 (29%), Positives = 95/237 (40%), Gaps = 61/237 (25%)
Query: 260 GSCFCNG-----HADQCIP-VHGFRPVKAPGT-----------FHMVHGKCMCKHNTAGS 302
G C C D C P +GF P G+C+C+ G
Sbjct: 800 GQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGL 859
Query: 303 HCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDC 362
C C G+ G P+ CR C CNGHAD C N G C C
Sbjct: 860 RCDRCQR-----------GQWGFPS-CRPCVCNGHADEC-----------NTHTGACLGC 896
Query: 363 QHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGD--- 419
+ +T G++C+RC GF+ D R P+ C+PC C P G P + F + D
Sbjct: 897 RDHTGGEHCERCIAGFHGDPRLPYGG--QCRPCPC-PEG----PGSQRHFATSCHQDEYS 949
Query: 420 ----CPCKPGVAGRRCDRCMVGYWGFGDYG-----CRPCDCAGSCDPITGDCISSHT 467
C C+ G G RC+ C G+ FGD C+ C+C+G+ DP+ D HT
Sbjct: 950 QQIVCHCRAGYTGLRCEACAPGH--FGDPSRPGGRCQLCECSGNIDPMDPDACDPHT 1004
Score = 95.5 bits (236), Expect = 1e-19
Identities = 64/217 (29%), Positives = 81/217 (37%), Gaps = 56/217 (25%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C C+G+ D P P T G+C+ C H+T G HC HC P ++ +
Sbjct: 986 CECSGNIDPMDP-----DACDPHT-----GQCLRCLHHTEGPHCAHCKPGFHGQ------ 1029
Query: 321 GKTGAPNECRTCKCN---------GHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYC 371
A C C CN D CH D S G C C N +G C
Sbjct: 1030 ---AARQSCHRCTCNLLGTNPQQCPSPDQCHCDP---------SSGQCP-CLPNVQGPSC 1076
Query: 372 QRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRC 431
RC P F+ ++ C+PC+CHP + N T G C C+ G GR C
Sbjct: 1077 DRCAPNFWN-----LTSGHGCQPCACHPSRARGPTCNEFT------GQCHCRAGFGGRTC 1125
Query: 432 DRCMVGYWGFGDYGCRPCDC------AGSCDPITGDC 462
C +WG C CDC C TG C
Sbjct: 1126 SECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHC 1162
Score = 77.8 bits (190), Expect = 3e-14
Identities = 45/140 (32%), Positives = 59/140 (42%), Gaps = 26/140 (18%)
Query: 327 NECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPF 386
N C+CN + N GG C C+ G+ C C PG+Y
Sbjct: 778 NGALPCQCNPQGSL--------SSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG------ 822
Query: 387 SAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGC 446
P C+ C C G+ + C+ ++G C C+ G G RCDRC G WGF C
Sbjct: 823 FGPTGCQACQCSHEGALS------SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP--SC 874
Query: 447 RPCDCAG---SCDPITGDCI 463
RPC C G C+ TG C+
Sbjct: 875 RPCVCNGHADECNTHTGACL 894
Score = 36.2 bits (82), Expect = 0.094
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 19/91 (20%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCN-GHADTCHFDVNVWE 349
G C CK G C C P + W + G CR C C+ G A D E
Sbjct: 489 GSCYCKRLVTGRGCDRCLPGH----WGLSHDLLG----CRPCDCDVGGA----LDPQCDE 536
Query: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
+G C C+ + G+ C++ +PG++R
Sbjct: 537 GTGQ-----CH-CRQHMVGRRCEQVQPGYFR 561
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 351 bits (901), Expect = 1e-96
Identities = 189/465 (40%), Positives = 265/465 (56%), Gaps = 49/465 (10%)
Query: 33 ACNPRMGNLALGR--KLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAH- 89
AC+P G+L +GR +L A +TCG + + YC S + KC C++ +P+ +
Sbjct: 27 ACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEG----EQKCFICDSRFPYDPYD 82
Query: 90 ------LPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMFKSPRPAAMV 143
+ + + + WWQS + I+LDLEA F F+HLI+ FK+ RPAAM+
Sbjct: 83 QPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRPAAML 142
Query: 144 LDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGA---ICTSKYSSPFPCTGGEVIFKA 200
++RS D+G WK +KYFA +C+ +F +G +C SKYS P TGGEV+ K
Sbjct: 143 VERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKV 202
Query: 201 LSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPC-----QRNDLNEEPQHFTHYAIYD 255
L P ++ ENPYS +Q+ + +TNLR+ K + ++ND ++ +YA+Y+
Sbjct: 203 LDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDK----YYYALYE 258
Query: 256 FIVKGSCFCNGHADQCIPVHGFRP--VKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYND 313
IV+GSCFCNGHA +C P+ R PG MVHG+C+C+HNT G +C+ C + D
Sbjct: 259 MIVRGSCFCNGHASECRPMQKMRGDVFSPPG---MVHGQCVCQHNTDGPNCERCKDFFQD 315
Query: 314 RPWE-AADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQ 372
PW AAD + N CR+C CN H+ CHFD+ + ASG SGGVC+DCQHNTEGQ+C
Sbjct: 316 APWRPAADLQD---NACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCD 372
Query: 373 RCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPS----NGDCPCKPGVAG 428
RC+P FYRD + S P AC PC C P G+ + V+ DP+ G C CK V G
Sbjct: 373 RCRPLFYRDPLKTISDPYACIPCECDPDGT-ISGGICVSHSDPALGSVAGQCLCKENVEG 431
Query: 429 RRCDRCMVGYWGFG---DYGCRPCDC--AGS-----CDPITGDCI 463
+CD+C ++G GC+PCDC GS CD TG C+
Sbjct: 432 AKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCL 476
Score = 95.1 bits (235), Expect = 2e-19
Identities = 67/214 (31%), Positives = 87/214 (40%), Gaps = 49/214 (22%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CN + D V P + V G+C+ C HNT G++CQ C P + + +A
Sbjct: 970 CACNNNID----------VTDPESCSRVTGECLRCLHNTQGANCQLCKPGH----YGSAL 1015
Query: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQYCQRC 374
+T CR C C+ V+ E +CD C N G C RC
Sbjct: 1016 NQT-----CRRCSCHASG------VSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRC 1064
Query: 375 KPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRC 434
G++ C+ C C P S + CD G CPCK G G+RC C
Sbjct: 1065 ADGYWN-----LVPGRGCQSCDCDPRTS------QSSHCDQLTGQCPCKLGYGGKRCSEC 1113
Query: 435 MVGYWGFGDYGCRPCDC--AGS----CDPITGDC 462
Y+G C PCDC AG+ CDP TG C
Sbjct: 1114 QENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMC 1147
Score = 94.4 bits (233), Expect = 3e-19
Identities = 55/127 (43%), Positives = 64/127 (50%), Gaps = 19/127 (14%)
Query: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
CH +V +S +R GG C C+ G+ C RC G Y DL C PC CHP
Sbjct: 771 CHPQGSVG-SSCSRLGGQCQ-CKPLVVGRCCDRCSTGSY-DLGH-----HGCHPCHCHPQ 822
Query: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC---AGSCDP 457
GS T CD G CPC V+GRRCDRC+ GY+GF C PC C A CDP
Sbjct: 823 GS------KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP--SCHPCPCNRFAELCDP 874
Query: 458 ITGDCIS 464
TG C +
Sbjct: 875 ETGSCFN 881
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 40/206 (19%)
Query: 271 CIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECR 330
C P H V G+C C +G C C Y P C
Sbjct: 814 CHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP------------SCH 861
Query: 331 TCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPD 390
C CN A+ C + G C +C T G+ C+RC G+Y + S+
Sbjct: 862 PCPCNRFAELCDPET-----------GSCFNCGGFTTGRNCERCIDGYYGNP----SSGQ 906
Query: 391 ACKPCSC--HPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG---FGDYG 445
C+PC C P + + S+ C C G G +C C G++G
Sbjct: 907 PCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAP 966
Query: 446 CRPCDCAG--------SCDPITGDCI 463
C+PC C SC +TG+C+
Sbjct: 967 CQPCACNNNIDVTDPESCSRVTGECL 992
Score = 74.7 bits (182), Expect = 2e-13
Identities = 46/151 (30%), Positives = 63/151 (41%), Gaps = 32/151 (21%)
Query: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGH-ADTCHFDVNV 347
V G C C N G C CA Y W G+ C++C C+ + + H D
Sbjct: 1046 VTGACPCLPNVTGLACDRCADGY----WNLVPGRG-----CQSCDCDPRTSQSSHCD--- 1093
Query: 348 WEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPA 407
+ G C C+ G+ C C+ +Y D P C PC C+ G+
Sbjct: 1094 ------QLTGQCP-CKLGYGGKRCSECQENYYGD------PPGRCIPCDCNRAGT----- 1135
Query: 408 NSVTFCDPSNGDCPCKPGVAGRRCDRCMVGY 438
CDP G C C+ GV+G+RCDRC G+
Sbjct: 1136 -QKPICDPDTGMCRCREGVSGQRCDRCARGH 1165
Score = 69.3 bits (168), Expect = 1e-11
Identities = 34/79 (43%), Positives = 38/79 (48%), Gaps = 12/79 (15%)
Query: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449
D C CHP GS + C G C CKP V GR CDRC G + G +GC PC
Sbjct: 764 DGAVACKCHPQGSVG------SSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPC 817
Query: 450 DC--AGS----CDPITGDC 462
C GS CD +TG C
Sbjct: 818 HCHPQGSKDTVCDQVTGQC 836
Score = 64.7 bits (156), Expect = 2e-10
Identities = 51/157 (32%), Positives = 69/157 (43%), Gaps = 26/157 (16%)
Query: 331 TCKCNGHADTCH----FDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPF 386
+C CNGHA C +V+ G G CQHNT+G C+RCK F RP
Sbjct: 264 SCFCNGHASECRPMQKMRGDVFSPPGMVHGQCV--CQHNTDGPNCERCKDFFQDAPWRPA 321
Query: 387 S--APDACKPCSCHPVGSAVLPANSVTFCDP---SNGDCP-CKPGVAGRRCDRCMVGYWG 440
+ +AC+ CSC+ S + T+ S G C C+ G+ CDRC ++
Sbjct: 322 ADLQDNACRSCSCNSHSSRC-HFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYR 380
Query: 441 ------FGDYGCRPCDCAGSCDP---ITGDCISSHTD 468
Y C PC+ CDP I+G SH+D
Sbjct: 381 DPLKTISDPYACIPCE----CDPDGTISGGICVSHSD 413
Score = 64.7 bits (156), Expect = 2e-10
Identities = 51/166 (30%), Positives = 61/166 (36%), Gaps = 43/166 (25%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCN--GHADTCHFDVNVW 348
G+C CK G C C+ D G G C C C+ G DT V
Sbjct: 786 GQCQCKPLVVGRCCDRCSTGSYDL------GHHG----CHPCHCHPQGSKDTVCDQVT-- 833
Query: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
G C C G+ C RC G+ F P +C PC C+
Sbjct: 834 --------GQC-PCHGEVSGRRCDRCLAGY-------FGFP-SCHPCPCN---------R 867
Query: 409 SVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWGFGDYG--CRPCDC 451
CDP G C C GR C+RC+ GY+G G CRPC C
Sbjct: 868 FAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLC 913
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 305 bits (782), Expect = 6e-83
Identities = 181/467 (38%), Positives = 246/467 (52%), Gaps = 48/467 (10%)
Query: 20 LSGVAGVSSRCEK-ACNPRMGNLALGRK--LWADTTCGQNATELYCFYSENTDLTCRQPK 76
L G+ C + AC P +G+L +GR L A +TCG E YC T Q K
Sbjct: 11 LPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-----TQYGEWQMK 65
Query: 77 CDKCNAAYPH--LAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMF 134
C KC++ PH +H +A SS P WWQS DV+ +QLDL+ F +++ F
Sbjct: 66 CCKCDSRQPHNYYSHRVENVASSSG--PMRWWQSQNDVNPVSLQLDLDRRFQLQEVMMEF 123
Query: 135 KSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKG-------AICTSKYSS 187
+ P PA M+++RS DFGKTW+ Y+Y A +C++TF V++G C S
Sbjct: 124 QGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPR----VRQGRPQSWQDVRCQSLPQR 179
Query: 188 PFP-CTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQ 246
P GG+V + S K+QE +ITNLRV + P QR P
Sbjct: 180 PNARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP-QRG--YHPPS 236
Query: 247 HFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQH 306
+YA+ ++GSCFC+GHAD+C P G P T VH C+C+HNTAG +C+
Sbjct: 237 --AYYAVSQLRLQGSCFCHGHADRCAPKPGASA--GPSTAVQVHDVCVCQHNTAGPNCER 292
Query: 307 CAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNT 366
CAP YN+RPW A+G+ +EC+ C CNGH++TCHFD V+ AS GGVCD+C+ +T
Sbjct: 293 CAPFYNNRPWRPAEGQDA--HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHT 350
Query: 367 EGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGV 426
EG+ C+RC+ ++R+ R S + C C C P G+ +P CDP G C CK V
Sbjct: 351 EGKNCERCQLHYFRNRRPGASIQETCISCECDPDGA--VPGAP---CDPVTGQCVCKEHV 405
Query: 427 AGRRCDRCMVGYWGF---GDYGCRPCDC--AGS-----CDPITGDCI 463
G RCD C G+ G GC CDC GS CD +G C+
Sbjct: 406 QGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Score = 69.7 bits (169), Expect = 8e-12
Identities = 53/204 (25%), Positives = 77/204 (37%), Gaps = 47/204 (23%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C+C N G C CAP + W+ A G+ C C C+ H N
Sbjct: 449 GRCLCLPNVVGPKCDQCAPYH----WKLASGQG-----CEPCACDPH--------NSLSP 491
Query: 351 SGNRSGGVCDDCQHNTEGQYC-----QRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVL 405
N+ G C C+ G C ++C Y D+ C+ C C G+
Sbjct: 492 QCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYGDVAT------GCRACDCDFRGT--- 541
Query: 406 PANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISS 465
CD ++G C C+PG+ G RCD+C GY C +C P C +
Sbjct: 542 ---EGPGCDKASGRCLCRPGLTGPRCDQCQRGY-------CNRYPVCVACHP----CFQT 587
Query: 466 HTDIDWYHEVPDFRPVHNKSEPAW 489
+ D D + F + N + W
Sbjct: 588 Y-DADLREQALRFGRLRNATASLW 610
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 305 bits (782), Expect = 6e-83
Identities = 181/467 (38%), Positives = 246/467 (52%), Gaps = 48/467 (10%)
Query: 20 LSGVAGVSSRCEK-ACNPRMGNLALGRK--LWADTTCGQNATELYCFYSENTDLTCRQPK 76
L G+ C + AC P +G+L +GR L A +TCG E YC T Q K
Sbjct: 11 LPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-----TQYGEWQMK 65
Query: 77 CDKCNAAYPH--LAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMF 134
C KC++ PH +H +A SS P WWQS DV+ +QLDL+ F +++ F
Sbjct: 66 CCKCDSRQPHNYYSHRVENVASSSG--PMRWWQSQNDVNPVSLQLDLDRRFQLQEVMMEF 123
Query: 135 KSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKG-------AICTSKYSS 187
+ P PA M+++RS DFGKTW+ Y+Y A +C++TF V++G C S
Sbjct: 124 QGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPR----VRQGRPQSWQDVRCQSLPQR 179
Query: 188 PFP-CTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQ 246
P GG+V + S K+QE +ITNLRV + P QR P
Sbjct: 180 PNARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP-QRG--YHPPS 236
Query: 247 HFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQH 306
+YA+ ++GSCFC+GHAD+C P G P T VH C+C+HNTAG +C+
Sbjct: 237 --AYYAVSQLRLQGSCFCHGHADRCAPKPGASA--GPSTAVQVHDVCVCQHNTAGPNCER 292
Query: 307 CAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNT 366
CAP YN+RPW A+G+ +EC+ C CNGH++TCHFD V+ AS GGVCD+C+ +T
Sbjct: 293 CAPFYNNRPWRPAEGQDA--HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHT 350
Query: 367 EGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGV 426
EG+ C+RC+ ++R+ R S + C C C P G+ +P CDP G C CK V
Sbjct: 351 EGKNCERCQLHYFRNRRPGASIQETCISCECDPDGA--VPGAP---CDPVTGQCVCKEHV 405
Query: 427 AGRRCDRCMVGYWGF---GDYGCRPCDC--AGS-----CDPITGDCI 463
G RCD C G+ G GC CDC GS CD +G C+
Sbjct: 406 QGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Score = 69.7 bits (169), Expect = 8e-12
Identities = 53/204 (25%), Positives = 77/204 (37%), Gaps = 47/204 (23%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C+C N G C CAP + W+ A G+ C C C+ H N
Sbjct: 449 GRCLCLPNVVGPKCDQCAPYH----WKLASGQG-----CEPCACDPH--------NSLSP 491
Query: 351 SGNRSGGVCDDCQHNTEGQYC-----QRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVL 405
N+ G C C+ G C ++C Y D+ C+ C C G+
Sbjct: 492 QCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYGDVAT------GCRACDCDFRGT--- 541
Query: 406 PANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISS 465
CD ++G C C+PG+ G RCD+C GY C +C P C +
Sbjct: 542 ---EGPGCDKASGRCLCRPGLTGPRCDQCQRGY-------CNRYPVCVACHP----CFQT 587
Query: 466 HTDIDWYHEVPDFRPVHNKSEPAW 489
+ D D + F + N + W
Sbjct: 588 Y-DADLREQALRFGRLRNATASLW 610
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 305 bits (782), Expect = 6e-83
Identities = 181/467 (38%), Positives = 246/467 (52%), Gaps = 48/467 (10%)
Query: 20 LSGVAGVSSRCEK-ACNPRMGNLALGRK--LWADTTCGQNATELYCFYSENTDLTCRQPK 76
L G+ C + AC P +G+L +GR L A +TCG E YC T Q K
Sbjct: 11 LPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-----TQYGEWQMK 65
Query: 77 CDKCNAAYPH--LAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMF 134
C KC++ PH +H +A SS P WWQS DV+ +QLDL+ F +++ F
Sbjct: 66 CCKCDSRQPHNYYSHRVENVASSSG--PMRWWQSQNDVNPVSLQLDLDRRFQLQEVMMEF 123
Query: 135 KSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKG-------AICTSKYSS 187
+ P PA M+++RS DFGKTW+ Y+Y A +C++TF V++G C S
Sbjct: 124 QGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPR----VRQGRPQSWQDVRCQSLPQR 179
Query: 188 PFP-CTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQ 246
P GG+V + S K+QE +ITNLRV + P QR P
Sbjct: 180 PNARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP-QRG--YHPPS 236
Query: 247 HFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQH 306
+YA+ ++GSCFC+GHAD+C P G P T VH C+C+HNTAG +C+
Sbjct: 237 --AYYAVSQLRLQGSCFCHGHADRCAPKPGASA--GPSTAVQVHDVCVCQHNTAGPNCER 292
Query: 307 CAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNT 366
CAP YN+RPW A+G+ +EC+ C CNGH++TCHFD V+ AS GGVCD+C+ +T
Sbjct: 293 CAPFYNNRPWRPAEGQDA--HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHT 350
Query: 367 EGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGV 426
EG+ C+RC+ ++R+ R S + C C C P G+ +P CDP G C CK V
Sbjct: 351 EGKNCERCQLHYFRNRRPGASIQETCISCECDPDGA--VPGAP---CDPVTGQCVCKEHV 405
Query: 427 AGRRCDRCMVGYWGF---GDYGCRPCDC--AGS-----CDPITGDCI 463
G RCD C G+ G GC CDC GS CD +G C+
Sbjct: 406 QGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Score = 69.7 bits (169), Expect = 8e-12
Identities = 53/204 (25%), Positives = 77/204 (37%), Gaps = 47/204 (23%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C+C N G C CAP + W+ A G+ C C C+ H N
Sbjct: 449 GRCLCLPNVVGPKCDQCAPYH----WKLASGQG-----CEPCACDPH--------NSLSP 491
Query: 351 SGNRSGGVCDDCQHNTEGQYC-----QRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVL 405
N+ G C C+ G C ++C Y D+ C+ C C G+
Sbjct: 492 QCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYGDVAT------GCRACDCDFRGT--- 541
Query: 406 PANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISS 465
CD ++G C C+PG+ G RCD+C GY C +C P C +
Sbjct: 542 ---EGPGCDKASGRCLCRPGLTGPRCDQCQRGY-------CNRYPVCVACHP----CFQT 587
Query: 466 HTDIDWYHEVPDFRPVHNKSEPAW 489
+ D D + F + N + W
Sbjct: 588 Y-DADLREQALRFGRLRNATASLW 610
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 297 bits (761), Expect = 2e-80
Identities = 199/650 (30%), Positives = 303/650 (46%), Gaps = 82/650 (12%)
Query: 1 MGSCARLLLLWGCTVVAAGLSGVAGVSSRCE---------KACNPRMGNLALGRKLWADT 51
+ + A + L G GLS AG +++ + + C P N A G+ + +
Sbjct: 9 LAALAAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSS 68
Query: 52 TCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAED 111
TCG+ YC SE + R C CNA+ P AH P+ + D + T WQS
Sbjct: 69 TCGRPPAR-YCVVSERGEERLRS--CHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENY 125
Query: 112 V---HREKIQLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATF 168
+ H + L L +F T++ + F SPRP +M + +S D+G+TW P+++++T C +
Sbjct: 126 LQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
Query: 169 GLED--DVVKKG---AICTSKYSSPFPCTGGEVIFKALS---PPYDTENPYSAKVQEQLK 220
+ K+ A+CT ++ P +GG + F L +D +N S +Q+ +
Sbjct: 186 NRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDN--SPVLQDWVT 243
Query: 221 ITNLRVQLLKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPV 280
T++RV + + + D +E + YA+ D V G C CNGHA +C+ V
Sbjct: 244 ATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLV 303
Query: 281 KAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADT 340
C C+HNTAG C C P + DRPW+ A + NEC C CN HA
Sbjct: 304 ------------CDCRHNTAGPECDRCKPFHYDRPWQRATAREA--NECVACNCNLHARR 349
Query: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
C F++ +++ SG +SGGVC +C+HNT G++C CK G+YRD+ +P + ACK C CHPV
Sbjct: 350 CRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPV 409
Query: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITG 460
G+A N T G CPCK GV G C+RC GY S PI
Sbjct: 410 GAAGKTCNQTT------GQCPCKDGVTGITCNRCAKGY-------------QQSRSPI-A 449
Query: 461 DCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFC 520
CI PV + A E+ + + + K + K N K +C
Sbjct: 450 PCIKI--------------PVAPPTTAASSVEEPEDCDSYCKASKGKLKI----NMKKYC 491
Query: 521 GMKYSYVLKIKILSAHDKGTHVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPI 580
K Y ++I IL A G + V I V K +I RG ++L+ S D C CP
Sbjct: 492 --KKDYAVQIHILKADKAGDWWKFTVNIISVYKQGTSRIRRGDQSLWIRS-RDIACKCPK 548
Query: 581 LNPGLEYLVAGHEDIRTGK--LIVNMKSFVQHWKPSLGRKVMDILKRECK 628
+ P +YL+ G+ + + ++ + S V W+ + R++ +RE K
Sbjct: 549 IKPLKKYLLLGNAEDSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKK 598
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 245 bits (626), Expect = 8e-65
Identities = 151/452 (33%), Positives = 220/452 (48%), Gaps = 59/452 (13%)
Query: 34 CNPRMGNLALGRKLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSA 93
C P N A + A TCG E YC + T +T C C+A PHL H +
Sbjct: 50 CMPEFVNAAFNVTVVATNTCGTPPEE-YCVQTGVTGVT---KSCHLCDAGQPHLQHGAAF 105
Query: 94 MADSSFRFPRTWWQS------AEDVHREKIQLDLEAEFYFTHLIVMFKSPRPAAMVLDRS 147
+ D + + TWWQS + + L L F T++ + F + RP + + +
Sbjct: 106 LTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKR 165
Query: 148 QDFGKTWKPYKYFATNCSATFGLED-DVVKKG-----AICTSKYSSPFPCTGGEVIFKAL 201
W PY+Y++ +C T+ + ++ G A+CT ++S P TGG V F L
Sbjct: 166 TREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTL 225
Query: 202 S---PPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQHFT--HYAIYDF 256
Y+ +N S +QE + T++RV L + + +++ +P+ +YAI DF
Sbjct: 226 EGRPSAYNFDN--SPVLQEWVTATDIRVTLNRLNTFG---DEVFNDPKVLKSYYYAISDF 280
Query: 257 IVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPW 316
V G C CNGHA +C+ + V C CKHNT G C+ C P +NDRPW
Sbjct: 281 AVGGRCKCNGHASECMKNEFDKLV------------CNCKHNTYGVDCEKCLPFFNDRPW 328
Query: 317 EAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKP 376
A ++ + EC C CNG + C+FD ++ ++G+ GG C +CQ NT+G +C+RC+
Sbjct: 329 RRATAESAS--ECLPCDCNGRSQECYFDPELYRSTGH--GGHCTNCQDNTDGAHCERCRE 384
Query: 377 GFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMV 436
F+R +AC C C PVGS T CD S G C CKPGV G +CDRC
Sbjct: 385 NFFR-----LGNNEACSSCHCSPVGSLS------TQCD-SYGRCSCKPGVMGDKCDRCQP 432
Query: 437 GYWGFGDYGCRPCDCAGS-----CDPITGDCI 463
G+ + GCRPC C S C+ TG C+
Sbjct: 433 GFHSLTEAGCRPCSCDPSGSIDECNIETGRCV 464
Score = 109 bits (273), Expect = 7e-24
Identities = 89/325 (27%), Positives = 115/325 (35%), Gaps = 87/325 (26%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
C CNGH++ C P G C C+ NTAG HC+ C+ Y D
Sbjct: 724 CACNGHSETCDPETGV---------------CNCRDNTAGPHCEKCSDGY------YGDS 762
Query: 322 KTGAPNECRTCKCNGHAD------------------------------------------ 339
G ++C+ C C G +
Sbjct: 763 TAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPV 822
Query: 340 ----TCHFDVNV-WEASGN--RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDAC 392
C N+ A GN R G C C +NT G YC RCK GF+ + P A D C
Sbjct: 823 RLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPA-DKC 881
Query: 393 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF-GDYGCRPCDC 451
K C+C+ G+ + C+P G C C P V G+ C C G++ GC CDC
Sbjct: 882 KACNCNLYGT----MKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDC 937
Query: 452 ------AGSCDPITGDCISSHTDIDWYH----EVPDFRPVHNKSEPAWEWEDAQGFSALL 501
G CD TG C I H EV F +P +
Sbjct: 938 HALGSTNGQCDIRTGQC-ECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCK 996
Query: 502 HSGKCECKEQTLGNAKAFCGMKYSY 526
G+CEC+E +GN C Y Y
Sbjct: 997 DDGRCECREGFVGNRCDQCEENYFY 1021
Score = 89.7 bits (221), Expect = 7e-18
Identities = 59/187 (31%), Positives = 82/187 (43%), Gaps = 42/187 (22%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C C G C+ C Y G + C C CNGH++TC
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRET-----PNLGPYSPCVLCACNGHSETC----------- 733
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGS--AVLPANSV 410
+ GVC +C+ NT G +C++C G+Y D S+ C+PC C P GS AV+P
Sbjct: 734 DPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSD--CQPCPC-PGGSSCAVVPKTKE 789
Query: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWG--FGDYG----CRPCDCA--------GSCD 456
C C G G+RC+ C GY+G G G CR C C+ G+C+
Sbjct: 790 VVC------TNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCN 843
Query: 457 PITGDCI 463
+TG+C+
Sbjct: 844 RLTGECL 850
Score = 77.8 bits (190), Expect = 3e-14
Identities = 52/195 (26%), Positives = 76/195 (38%), Gaps = 49/195 (25%)
Query: 280 VKAPGTFHMVHGKCMCKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRTCKCNGHA 338
+K + + V G+C C + G C C P YN + + C C C+
Sbjct: 892 MKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQG----------CERCDCHALG 941
Query: 339 DTCHFDVNVWEASGNRSGGVCD------DCQHNTEGQYCQRCKPGFYRDLRRPFSAPDAC 392
T G CD +CQ GQ+C+RC+ + P+ C
Sbjct: 942 ST---------------NGQCDIRTGQCECQPGITGQHCERCEVNHFG------FGPEGC 980
Query: 393 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY-GCRPCDC 451
KPC CHP GS L +G C C+ G G RCD+C Y+ + GC+ C
Sbjct: 981 KPCDCHPEGSLSLQCK-------DDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECP- 1032
Query: 452 AGSCDPITGDCISSH 466
+C + D ++ H
Sbjct: 1033 --ACYRLVKDKVADH 1045
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 242 bits (617), Expect = 9e-64
Identities = 164/533 (30%), Positives = 232/533 (43%), Gaps = 123/533 (23%)
Query: 35 NPRMGNLALGRKLWADTTCGQNAT---------ELYC------FYSENTDLTCRQPKCDK 79
+P NLA G ++ A TCG+ A +LYC + + T R CD
Sbjct: 46 HPPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDI 105
Query: 80 CNAAYPHLAHLPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLIVMF 134
C AA + AH S D + R WWQS + + + LDL F+ ++++ F
Sbjct: 106 CTAANSNKAHPASNAIDGTER----WWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKF 161
Query: 135 -KSPRPAAMVLDRSQDFGKTWKPYKYFATN---CSATFG---LEDDVVKKGAICTSKYSS 187
SPRP VL+RS DFG+T++P+++FA++ C FG LE AICT++YS
Sbjct: 162 ANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSR 221
Query: 188 PFPCTGGEVIFKALSPPYDTEN-PYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQ 246
P GE++ ++ N YS ++E K TN+R++ L+ +
Sbjct: 222 IVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDP 281
Query: 247 HFT---HYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSH 303
T +Y+I D + G C C+GHAD C P + +C C+HNT G
Sbjct: 282 TVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRL---------QCTCQHNTCGGT 332
Query: 304 CQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRS-------G 356
C C P +N +PW+ A + NEC++C C GHA C++D V ++S G
Sbjct: 333 CDRCCPGFNQQPWKPATANSA--NECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGG 390
Query: 357 GVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPC--------------------- 395
GVC DCQH+T G C+RC PGFYR P +P C+ C
Sbjct: 391 GVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCR 450
Query: 396 -------------------SCHPVGSA-------VLPANSVTFC--------------DP 415
SC+P S+ VLPA + C DP
Sbjct: 451 PNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDP 510
Query: 416 SNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG------SCDPITGDC 462
G C CKP G C+ C G++G GC+PC C+ CDP TG C
Sbjct: 511 RVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGVADDRCDPDTGQC 560
Score = 117 bits (292), Expect = 4e-26
Identities = 63/177 (35%), Positives = 83/177 (46%), Gaps = 30/177 (16%)
Query: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEAS 351
+C+CK AG+ C+ CAP + P + C+ C C+G+ D N+ +
Sbjct: 1936 QCLCKPGYAGASCERCAPGFFGNPLVLG-------SSCQPCDCSGNGDP-----NLLFSD 1983
Query: 352 GNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVT 411
+ G C C +T G C+ C PGFY + P C C C P G+
Sbjct: 1984 CDPLTGACRGCLRHTTGPRCEICAPGFYGNA----LLPGNCTRCDCTPCGTEA------- 2032
Query: 412 FCDPSNGDCPCKPGVAGRRCDRCMVGYWGF-GDYGCRPCDC-----AGSCDPITGDC 462
CDP +G C CK GV GRRCDRC G++GF G GCRPC C C P +G C
Sbjct: 2033 -CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQC 2088
Score = 112 bits (281), Expect = 8e-25
Identities = 67/185 (36%), Positives = 84/185 (45%), Gaps = 39/185 (21%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C+C + G CQ CAP + D K C C+C+GH+D C
Sbjct: 1831 CLCPASYRGDSCQECAPGFY------RDVKGLFLGRCVPCQCHGHSDRCL---------- 1874
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
GVC DCQHNTEG +C+RC+ GF S D PC P +V N
Sbjct: 1875 -PGSGVCVDCQHNTEGAHCERCQAGFVS------SRDDPSAPCVSCPCPLSVPSNNFAEG 1927
Query: 413 CDPSNG--DCPCKPGVAGRRCDRCMVGYWG----FGDYGCRPCDCAGS---------CDP 457
C G C CKPG AG C+RC G++G G C+PCDC+G+ CDP
Sbjct: 1928 CVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGS-SCQPCDCSGNGDPNLLFSDCDP 1986
Query: 458 ITGDC 462
+TG C
Sbjct: 1987 LTGAC 1991
Score = 92.0 bits (227), Expect = 1e-18
Identities = 74/253 (29%), Positives = 101/253 (39%), Gaps = 57/253 (22%)
Query: 260 GSCFCNG-----HADQCIP-VHGFRPVKA-----PGTFHMVHGK---CMCKHNTAGSHCQ 305
G C C H D+C P HGF +A G + G C C+ G+ CQ
Sbjct: 603 GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
Query: 306 HCAPLYNDRP-----WEAADGKTGAPNECRTCKCNGH-------ADTC---HFDVNVWEA 350
C+P ++ P +A+G A + R+ +C+ DTC ++ EA
Sbjct: 663 ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEA 722
Query: 351 SGNRSGGVCDD------------CQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCH 398
G+ C+ + EG C RCKPGF+ S P+ C CSC
Sbjct: 723 GSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWG---LSPSNPEGCTRCSCD 779
Query: 399 PVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDC---- 451
G+ V C P G C CKP V G+ C C G++G +GCR C C
Sbjct: 780 LRGTL----GGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGG 835
Query: 452 --AGSCDPITGDC 462
SC+P TG C
Sbjct: 836 ALGQSCEPRTGVC 848
Score = 86.3 bits (212), Expect = 8e-17
Identities = 68/238 (28%), Positives = 94/238 (39%), Gaps = 60/238 (25%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHA---DTCHFDVNV 347
G+C+CK N G+HC+ CAP + P C+ C+C+ D C D
Sbjct: 513 GRCLCKPNFQGTHCELCAPGFY------------GPG-CQPCQCSSPGVADDRCDPDT-- 557
Query: 348 WEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPA 407
G C C+ EG C RC PG++ C+ C C P G+ LP
Sbjct: 558 ---------GQCR-CRVGFEGATCDRCAPGYFHF--------PLCQLCGCSPAGT--LPE 597
Query: 408 NSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITG-----DC 462
CD + G C C+P AG CDRC GY GF + CD G+ D + G C
Sbjct: 598 G----CDEA-GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRC 652
Query: 463 ISSHTDI------DWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLG 514
+T +H P P H +E + + SG+C C+ + G
Sbjct: 653 RPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLH------AACDPRSGQCSCRPRVTG 704
Score = 83.2 bits (204), Expect = 7e-16
Identities = 67/215 (31%), Positives = 81/215 (37%), Gaps = 59/215 (27%)
Query: 261 SCFCNGHADQCIPVHGFRPVKAPG-TFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAA 319
S F N A C G V A G T G+C C + G C CA Y W
Sbjct: 1428 SLFYNNGARPC----GCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGY----W--- 1476
Query: 320 DGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQYCQR 373
G PN CR C C +CD+ C T C
Sbjct: 1477 ----GFPN-CRPCDCGAR--------------------LCDELTGQCICPPRTIPPDCLL 1511
Query: 374 CKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDR 433
C+P + P C+ C+C G L + CD +G C C+P V GRRCD
Sbjct: 1512 CQPQTFGC--HPLVG---CEECNCSGPGIQELTDPT---CDTDSGQCKCRPNVTGRRCDT 1563
Query: 434 CMVGYWGFGDYGCRPCDC------AGSCDPITGDC 462
C G+ G+ CRPCDC G CDP+TG C
Sbjct: 1564 CSPGFHGYP--RCRPCDCHEAGTAPGVCDPLTGQC 1596
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/165 (32%), Positives = 69/165 (41%), Gaps = 27/165 (16%)
Query: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449
+ +PC CH VG+ + C+P G CPC V GR C RC GYWGF + CRPC
Sbjct: 1433 NGARPCGCHEVGA------TGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN--CRPC 1484
Query: 450 DC-AGSCDPITGDCISSHTDIDWYHEVPD---FRPVHNKSEPAWEWEDAQ----GFSAL- 500
DC A CD +TG CI I PD +P P E+ G L
Sbjct: 1485 DCGARLCDELTGQCICPPRTIP-----PDCLLCQPQTFGCHPLVGCEECNCSGPGIQELT 1539
Query: 501 -----LHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGT 540
SG+C+C+ G C + + + H+ GT
Sbjct: 1540 DPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGT 1584
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 239 bits (610), Expect = 6e-63
Identities = 158/494 (31%), Positives = 226/494 (45%), Gaps = 71/494 (14%)
Query: 7 LLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNAT-------E 59
L +L C A AG+S +P NLA ++WA TCG+ E
Sbjct: 26 LRVLPACGATARDPGAAAGLS------LHPTYFNLAEAARIWATATCGERGPGEGRPQPE 79
Query: 60 LYCFY-----SENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQS-----A 109
LYC + + T + CD CN+ P AH + D S R WWQS
Sbjct: 80 LYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSER----WWQSPPLSSG 135
Query: 110 EDVHREKIQLDLEAEFYFTHLIVMF-KSPRPAAMVLDRSQDFGKTWKPYKYFA---TNCS 165
+R + LDL F+ ++++ F SPRP VL+RS DFG T+ P++YFA +C
Sbjct: 136 TQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCL 195
Query: 166 ATFGLEDDVV---KKGAICTSKYSSPFPCTGGEVIFKALSPPYDTEN-PYSAKVQEQLKI 221
FG E ++ +C ++YS P GEV+ ++ +N +S ++E K
Sbjct: 196 KEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKA 255
Query: 222 TNLRVQLLKRQSCPCQRNDLNEEPQHFT---HYAIYDFIVKGSCFCNGHADQCIPVHGFR 278
TN+R++ L+ + + T +Y+I D + G C CNGHA+ C
Sbjct: 256 TNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVC------- 308
Query: 279 PVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHA 338
+ P +C C+H+T G C C YN R W A + +EC C C+GHA
Sbjct: 309 NINNPEKLF----RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS--HECEACNCHGHA 362
Query: 339 DTCHFDVNV--WEASGNRSG-----GVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA 391
C++D +V +AS N G GVC +CQHNT G C++C G+YR P APD
Sbjct: 363 SNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDG 422
Query: 392 CKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCR---- 447
C PCSC P C+ +G C CKP G C++C +GY+ F + R
Sbjct: 423 CIPCSCDP--------EHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNF-PFCLRIPIF 473
Query: 448 PCDCAGSCDPITGD 461
P S DP+ GD
Sbjct: 474 PVSTPSSEDPVAGD 487
Score = 115 bits (289), Expect = 9e-26
Identities = 65/183 (35%), Positives = 86/183 (46%), Gaps = 40/183 (21%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C C AG CQ C+P Y D K C C CNGH++ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY------RDHKGLYTGRCVPCNCNGHSNQCQ---------- 1697
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
G+C +CQHNT G++C+RC+ G+Y + + +C+ C C S T
Sbjct: 1698 -DGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPHTNS------FATG 1745
Query: 413 CDPSNGD--CPCKPGVAGRRCDRCMVGYWG----FGDYGCRPCDC-----AGSCDPITGD 461
C + GD C CK G G +C+RC GY+G FG C+PC C GSC P+TGD
Sbjct: 1746 CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG-SCQPCSCNSNGQLGSCHPLTGD 1804
Query: 462 CIS 464
CI+
Sbjct: 1805 CIN 1807
Score = 90.1 bits (222), Expect = 5e-18
Identities = 76/261 (29%), Positives = 102/261 (39%), Gaps = 75/261 (28%)
Query: 261 SCFCNGHADQCIPVHGFRPVKAPGTFHMVH---GKCM-CKHNTAGSHCQHCAPLYNDRPW 316
+C C+GHA C +A ++ G C+ C+HNTAG +C+ CA Y RP+
Sbjct: 355 ACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPY 413
Query: 317 -----------------EAADGKTGAPNECRTCKCNGHADTCH----------------- 342
E ADG C CK N H D C
Sbjct: 414 GVPVDAPDGCIPCSCDPEHADGCEQGSGRCH-CKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
Query: 343 FDVNVWEASGNRSGGV--------------CDD-----CQHNTEGQYCQRCKPGFYRDLR 383
F V+ + +G + CD C+ EG C C+ GFY
Sbjct: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY---- 528
Query: 384 RPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFG- 442
S P C+ C C +GS +P +SVT G C C+PGV G+RCDRC+ G + F
Sbjct: 529 ---SFP-ICQACWCSALGSYQMPCSSVT------GQCECRPGVTGQRCDRCLSGAYDFPH 578
Query: 443 -DYGCRPCDCAGSCDPITGDC 462
CD AG+ + G C
Sbjct: 579 CQGSSSACDPAGTINSNLGYC 599
Score = 80.5 bits (197), Expect = 4e-15
Identities = 85/330 (25%), Positives = 123/330 (37%), Gaps = 86/330 (26%)
Query: 159 YFATNCSATFGLEDDVVKKGAICTSKYSSP-------FPCTGGEVIFKALSPP---YDTE 208
+ A+ C G D V+ +G I S P P V+ + L P YD +
Sbjct: 1157 FHASFCPHVLGCRDQVIAEGQI-EFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQ 1215
Query: 209 NPYSAKVQEQLK-ITNLRVQLLKRQSCPCQRNDLNEEPQHFTHY------AIYDFIVKGS 261
+ + + L+ ITN C +N +PQ + + ++ F KG+
Sbjct: 1216 ILHKKSMDKSLEFITN------------CGKNSFYLDPQTASRFCKNSARSLVAFYHKGA 1263
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
C +C P P +P G+C C+ N G C CA G
Sbjct: 1264 LPC-----ECHPTGATGPHCSPEG-----GQCPCQPNVIGRQCTRCAT-----------G 1302
Query: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
G P C+ C C C G C C T C+ C+ +
Sbjct: 1303 HYGFPR-CKPCSCGRRL--CE-----------EMTGQCR-CPPRTVRPQCEVCETHSFS- 1346
Query: 382 LRRPFSAPDACKPCSCHPVGS--AVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
F C+ C+C G+ A +P CD +G C CKP + GR+CDRC G++
Sbjct: 1347 ----FHPMAGCEGCNCSRRGTIEAAMPE-----CDRDSGQCRCKPRITGRQCDRCASGFY 1397
Query: 440 GFGDYGCRPCDC------AGSCDPITGDCI 463
F + C PC+C G CDP TG C+
Sbjct: 1398 RFPE--CVPCNCNRDGTEPGVCDPGTGACL 1425
Score = 73.2 bits (178), Expect = 7e-13
Identities = 54/189 (28%), Positives = 72/189 (38%), Gaps = 35/189 (18%)
Query: 290 HGKCMCKHNTAGSHCQHCAPLYNDRP-----WEAADGKTGAPN-------ECRTCKCNGH 337
HG+C+C+ G C C + P W +A G P ECR
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQR 565
Query: 338 ADTC---HFDVNVWEASG---------NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRP 385
D C +D + S N + G C C+ + EG C RCK Y +L +
Sbjct: 566 CDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ-CKLHVEGPTCSRCKL-LYWNLDK- 622
Query: 386 FSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF---G 442
P C C CH G+ + C +GDC CK V G CD C GY+
Sbjct: 623 -ENPSGCSECKCHKAGTV----SGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSN 677
Query: 443 DYGCRPCDC 451
+GC+ C C
Sbjct: 678 YFGCQGCQC 686
Score = 70.9 bits (172), Expect = 3e-12
Identities = 51/180 (28%), Positives = 66/180 (36%), Gaps = 51/180 (28%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CNGH++QC G C+ C+HNTAG HC+ C Y
Sbjct: 1687 CNCNGHSNQCQDGSGI---------------CVNCQHNTAGEHCERCQEGYYG------- 1724
Query: 321 GKTGAPNECRTCKC---NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
CR C C N A C + G V C+ G C+RC PG
Sbjct: 1725 --NAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPG 1772
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC---PCKPGVAGRRCDRC 434
++ + P +C+PCSC+ G + C P GDC K CD C
Sbjct: 1773 YFGN---PQKFGGSCQPCSCNSNG-------QLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 32/176 (18%)
Query: 264 CNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKT 323
C G + C P GT + G C CK + G C C LY + E
Sbjct: 579 CQGSSSACDPA---------GTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKE------ 623
Query: 324 GAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLR 383
P+ C CK CH V R G C+ + G C C+ G++ +
Sbjct: 624 -NPSGCSECK-------CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEK 675
Query: 384 RPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
+ C+ C C +G A+ + C +G C C+ V G+ C R Y+
Sbjct: 676 SNYF---GCQGCQC-DIGGAL-----SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 26/135 (19%)
Query: 236 CQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHG---K 292
CQ N E + Y V GSC A C + F T +V+G +
Sbjct: 1706 CQHNTAGEHCERCQE-GYYGNAVHGSC----RACPCPHTNSF------ATGCVVNGGDVR 1754
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKC--NGHADTCH---FDVNV 347
C CK G+ C+ CAP Y P + C+ C C NG +CH D
Sbjct: 1755 CSCKAGYTGTQCERCAPGYFGNPQKFG-------GSCQPCSCNSNGQLGSCHPLTGDCIN 1807
Query: 348 WEASGNRSGGVCDDC 362
E + CDDC
Sbjct: 1808 QEPKDSSPAEECDDC 1822
Score = 35.4 bits (80), Expect = 0.16
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 7/73 (9%)
Query: 270 QCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNEC 329
+C+P + R PG G C+CK N G+ C C + A+ K C
Sbjct: 1401 ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE--GSFHLDPANLK-----GC 1453
Query: 330 RTCKCNGHADTCH 342
+C C G + CH
Sbjct: 1454 TSCFCFGVNNQCH 1466
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 239 bits (610), Expect = 6e-63
Identities = 158/494 (31%), Positives = 226/494 (45%), Gaps = 71/494 (14%)
Query: 7 LLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNAT-------E 59
L +L C A AG+S +P NLA ++WA TCG+ E
Sbjct: 26 LRVLPACGATARDPGAAAGLS------LHPTYFNLAEAARIWATATCGERGPGEGRPQPE 79
Query: 60 LYCFY-----SENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQS-----A 109
LYC + + T + CD CN+ P AH + D S R WWQS
Sbjct: 80 LYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSER----WWQSPPLSSG 135
Query: 110 EDVHREKIQLDLEAEFYFTHLIVMF-KSPRPAAMVLDRSQDFGKTWKPYKYFA---TNCS 165
+R + LDL F+ ++++ F SPRP VL+RS DFG T+ P++YFA +C
Sbjct: 136 TQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCL 195
Query: 166 ATFGLEDDVV---KKGAICTSKYSSPFPCTGGEVIFKALSPPYDTEN-PYSAKVQEQLKI 221
FG E ++ +C ++YS P GEV+ ++ +N +S ++E K
Sbjct: 196 KEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKA 255
Query: 222 TNLRVQLLKRQSCPCQRNDLNEEPQHFT---HYAIYDFIVKGSCFCNGHADQCIPVHGFR 278
TN+R++ L+ + + T +Y+I D + G C CNGHA+ C
Sbjct: 256 TNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVC------- 308
Query: 279 PVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHA 338
+ P +C C+H+T G C C YN R W A + +EC C C+GHA
Sbjct: 309 NINNPEKLF----RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS--HECEACNCHGHA 362
Query: 339 DTCHFDVNV--WEASGNRSG-----GVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA 391
C++D +V +AS N G GVC +CQHNT G C++C G+YR P APD
Sbjct: 363 SNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDG 422
Query: 392 CKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCR---- 447
C PCSC P C+ +G C CKP G C++C +GY+ F + R
Sbjct: 423 CIPCSCDP--------EHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNF-PFCLRIPIF 473
Query: 448 PCDCAGSCDPITGD 461
P S DP+ GD
Sbjct: 474 PVSTPSSEDPVAGD 487
Score = 115 bits (289), Expect = 9e-26
Identities = 65/183 (35%), Positives = 86/183 (46%), Gaps = 40/183 (21%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C C AG CQ C+P Y D K C C CNGH++ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY------RDHKGLYTGRCVPCNCNGHSNQCQ---------- 1697
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
G+C +CQHNT G++C+RC+ G+Y + + +C+ C C S T
Sbjct: 1698 -DGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPHTNS------FATG 1745
Query: 413 CDPSNGD--CPCKPGVAGRRCDRCMVGYWG----FGDYGCRPCDC-----AGSCDPITGD 461
C + GD C CK G G +C+RC GY+G FG C+PC C GSC P+TGD
Sbjct: 1746 CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG-SCQPCSCNSNGQLGSCHPLTGD 1804
Query: 462 CIS 464
CI+
Sbjct: 1805 CIN 1807
Score = 90.1 bits (222), Expect = 5e-18
Identities = 76/261 (29%), Positives = 102/261 (39%), Gaps = 75/261 (28%)
Query: 261 SCFCNGHADQCIPVHGFRPVKAPGTFHMVH---GKCM-CKHNTAGSHCQHCAPLYNDRPW 316
+C C+GHA C +A ++ G C+ C+HNTAG +C+ CA Y RP+
Sbjct: 355 ACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPY 413
Query: 317 -----------------EAADGKTGAPNECRTCKCNGHADTCH----------------- 342
E ADG C CK N H D C
Sbjct: 414 GVPVDAPDGCIPCSCDPEHADGCEQGSGRCH-CKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
Query: 343 FDVNVWEASGNRSGGV--------------CDD-----CQHNTEGQYCQRCKPGFYRDLR 383
F V+ + +G + CD C+ EG C C+ GFY
Sbjct: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY---- 528
Query: 384 RPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFG- 442
S P C+ C C +GS +P +SVT G C C+PGV G+RCDRC+ G + F
Sbjct: 529 ---SFP-ICQACWCSALGSYQMPCSSVT------GQCECRPGVTGQRCDRCLSGAYDFPH 578
Query: 443 -DYGCRPCDCAGSCDPITGDC 462
CD AG+ + G C
Sbjct: 579 CQGSSSACDPAGTINSNLGYC 599
Score = 80.5 bits (197), Expect = 4e-15
Identities = 85/330 (25%), Positives = 123/330 (37%), Gaps = 86/330 (26%)
Query: 159 YFATNCSATFGLEDDVVKKGAICTSKYSSP-------FPCTGGEVIFKALSPP---YDTE 208
+ A+ C G D V+ +G I S P P V+ + L P YD +
Sbjct: 1157 FHASFCPHVLGCRDQVIAEGQI-EFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQ 1215
Query: 209 NPYSAKVQEQLK-ITNLRVQLLKRQSCPCQRNDLNEEPQHFTHY------AIYDFIVKGS 261
+ + + L+ ITN C +N +PQ + + ++ F KG+
Sbjct: 1216 ILHKKSMDKSLEFITN------------CGKNSFYLDPQTASRFCKNSARSLVAFYHKGA 1263
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
C +C P P +P G+C C+ N G C CA G
Sbjct: 1264 LPC-----ECHPTGATGPHCSPEG-----GQCPCQPNVIGRQCTRCAT-----------G 1302
Query: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
G P C+ C C C G C C T C+ C+ +
Sbjct: 1303 HYGFPR-CKPCSCGRRL--CE-----------EMTGQCR-CPPRTVRPQCEVCETHSFS- 1346
Query: 382 LRRPFSAPDACKPCSCHPVGS--AVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
F C+ C+C G+ A +P CD +G C CKP + GR+CDRC G++
Sbjct: 1347 ----FHPMAGCEGCNCSRRGTIEAAMPE-----CDRDSGQCRCKPRITGRQCDRCASGFY 1397
Query: 440 GFGDYGCRPCDC------AGSCDPITGDCI 463
F + C PC+C G CDP TG C+
Sbjct: 1398 RFPE--CVPCNCNRDGTEPGVCDPGTGACL 1425
Score = 73.2 bits (178), Expect = 7e-13
Identities = 54/189 (28%), Positives = 72/189 (38%), Gaps = 35/189 (18%)
Query: 290 HGKCMCKHNTAGSHCQHCAPLYNDRP-----WEAADGKTGAPN-------ECRTCKCNGH 337
HG+C+C+ G C C + P W +A G P ECR
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQR 565
Query: 338 ADTC---HFDVNVWEASG---------NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRP 385
D C +D + S N + G C C+ + EG C RCK Y +L +
Sbjct: 566 CDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ-CKLHVEGPTCSRCKL-LYWNLDK- 622
Query: 386 FSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF---G 442
P C C CH G+ + C +GDC CK V G CD C GY+
Sbjct: 623 -ENPSGCSECKCHKAGTV----SGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSN 677
Query: 443 DYGCRPCDC 451
+GC+ C C
Sbjct: 678 YFGCQGCQC 686
Score = 70.9 bits (172), Expect = 3e-12
Identities = 51/180 (28%), Positives = 66/180 (36%), Gaps = 51/180 (28%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CNGH++QC G C+ C+HNTAG HC+ C Y
Sbjct: 1687 CNCNGHSNQCQDGSGI---------------CVNCQHNTAGEHCERCQEGYYG------- 1724
Query: 321 GKTGAPNECRTCKC---NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
CR C C N A C + G V C+ G C+RC PG
Sbjct: 1725 --NAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPG 1772
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC---PCKPGVAGRRCDRC 434
++ + P +C+PCSC+ G + C P GDC K CD C
Sbjct: 1773 YFGN---PQKFGGSCQPCSCNSNG-------QLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 32/176 (18%)
Query: 264 CNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKT 323
C G + C P GT + G C CK + G C C LY + E
Sbjct: 579 CQGSSSACDPA---------GTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKE------ 623
Query: 324 GAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLR 383
P+ C CK CH V R G C+ + G C C+ G++ +
Sbjct: 624 -NPSGCSECK-------CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEK 675
Query: 384 RPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
+ C+ C C +G A+ + C +G C C+ V G+ C R Y+
Sbjct: 676 SNYF---GCQGCQC-DIGGAL-----SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 26/135 (19%)
Query: 236 CQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHG---K 292
CQ N E + Y V GSC A C + F T +V+G +
Sbjct: 1706 CQHNTAGEHCERCQE-GYYGNAVHGSC----RACPCPHTNSF------ATGCVVNGGDVR 1754
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKC--NGHADTCH---FDVNV 347
C CK G+ C+ CAP Y P + C+ C C NG +CH D
Sbjct: 1755 CSCKAGYTGTQCERCAPGYFGNPQKFG-------GSCQPCSCNSNGQLGSCHPLTGDCIN 1807
Query: 348 WEASGNRSGGVCDDC 362
E + CDDC
Sbjct: 1808 QEPKDSSPAEECDDC 1822
Score = 35.4 bits (80), Expect = 0.16
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 7/73 (9%)
Query: 270 QCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNEC 329
+C+P + R PG G C+CK N G+ C C + A+ K C
Sbjct: 1401 ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE--GSFHLDPANLK-----GC 1453
Query: 330 RTCKCNGHADTCH 342
+C C G + CH
Sbjct: 1454 TSCFCFGVNNQCH 1466
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 234 bits (598), Expect = 1e-61
Identities = 159/486 (32%), Positives = 232/486 (47%), Gaps = 67/486 (13%)
Query: 5 ARLLLLWGCTVVAAGLSGVAGVSSRCEKA-----CNPRMGNLALGRKLWADTTCGQNATE 59
A LL G ++A +G AG+ + + A C P N A GR A TCG + E
Sbjct: 2 AAAALLLGLALLAPRAAG-AGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCG-SPPE 59
Query: 60 LYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREK--- 116
+C + C +C+AA P H S + D + TWWQS +
Sbjct: 60 DFC---PHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPT 116
Query: 117 ---IQLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGL-ED 172
I L L + T++ + F + RP + + + W+PY++++ +C T+G E
Sbjct: 117 SVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEG 176
Query: 173 DVVKKG-----AICTSKYSSPFPCTGGEVIFKALSPPYDTEN-PYSAKVQEQLKITNLRV 226
++ G A CTS++S P +GG V F L N S +QE + T L +
Sbjct: 177 QYLRPGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLI 236
Query: 227 QLLKRQSCPCQRNDLNEEPQHFT--HYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPG 284
L + + +D+ ++P+ +YA+ DF V G C CNGHA +C P
Sbjct: 237 SLDRLNTFG---DDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPD---------- 283
Query: 285 TFHMVHGK--CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCH 342
V G+ C C+HNT G+ C+ C P + DRPW A G A +EC C C+G ++ C
Sbjct: 284 ----VAGQLACRCQHNTTGTDCERCLPFFQDRPW--ARGTAEAAHECLPCNCSGRSEECT 337
Query: 343 FDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR-DLRRPFSAPDACKPCSCHPVG 401
FD ++ ++G+ GG C C+ +T G +C+RC+ FY D R P C+PC C G
Sbjct: 338 FDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENFYHWDPRMP------CQPCDCQSAG 389
Query: 402 SAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC--AGS---CD 456
S L CD + G C CKP V G +CDRC+ G+ + GCRPC C AGS CD
Sbjct: 390 SLHLQ------CDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCD 442
Query: 457 PITGDC 462
P +G C
Sbjct: 443 PRSGRC 448
Score = 112 bits (279), Expect = 1e-24
Identities = 78/265 (29%), Positives = 98/265 (36%), Gaps = 88/265 (33%)
Query: 260 GSCFCNGHAD-----QCIPVHGF------------RPVKAPGTFHMVHGKCMCKHNTAGS 302
G C C+ H + +C+P GF +P PG C +
Sbjct: 720 GICVCSHHTEGPSCERCLP--GFYGNPFAGQADDCQPCPCPG-----QSACTTIPESREV 772
Query: 303 HCQHCAPLYNDRPWEAAD--------GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNR 354
C HC P R E D G G P C C+C+G+ D A GN
Sbjct: 773 VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDP--------NAVGNC 824
Query: 355 S--GGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAV--LPANSV 410
G C C HNT G +C+ C+ GFY P A D C PCSCHP GS +P + V
Sbjct: 825 DPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPA-DKCMPCSCHPQGSVSEQMPCDPV 883
Query: 411 TF-------------------------------------------CDPSNGDCPCKPGVA 427
T C P G C C+PGV
Sbjct: 884 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVT 943
Query: 428 GRRCDRCMVGYWGFGDYGCRPCDCA 452
G+ CDRC +G++GF GCR C C+
Sbjct: 944 GQACDRCQLGFFGFSIKGCRACRCS 968
Score = 94.4 bits (233), Expect = 3e-19
Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 61/286 (21%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
C CN H GT G C+C H+T G C+ C P + P+
Sbjct: 707 CTCNQH----------------GTCDPNTGICVCSHHTEGPSCERCLPGFYGNPF----- 745
Query: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
G ++C+ C C G + C E VC C G+ C+ C GF+ D
Sbjct: 746 -AGQADDCQPCPCPGQS-ACTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGD 796
Query: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440
F P C C C S + N+V CDP +G C C G C+ C G++G
Sbjct: 797 PLGLFGHPQPCHQCQC----SGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG 852
Query: 441 FG-----DYGCRPCDC--AGS------CDPITGDC-----ISSHTDIDWYHEVPDFRPVH 482
C PC C GS CDP+TG C +++ Y D +P
Sbjct: 853 SALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGR 912
Query: 483 N----KSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKY 524
K P ED +G+C C+ G A C + +
Sbjct: 913 GCRSCKCHPLGSQED----QCHPKTGQCTCRPGVTGQACDRCQLGF 954
Score = 92.8 bits (229), Expect = 8e-19
Identities = 67/188 (35%), Positives = 85/188 (45%), Gaps = 45/188 (23%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C C G C+ CAP Y E G G C C CN H TC D N
Sbjct: 673 CSCPTGYTGQFCESCAPGYKR---EMPQG--GPYASCVPCTCNQHG-TC--DPNT----- 719
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSA-PDACKPCSCHPVGSA--VLPANS 409
G+C C H+TEG C+RC PGFY + PF+ D C+PC C P SA +P +
Sbjct: 720 ----GIC-VCSHHTEGPSCERCLPGFYGN---PFAGQADDCQPCPC-PGQSACTTIPESR 770
Query: 410 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG--FGDYG----CRPCDCA--------GSC 455
C C PG GRRC+ C G++G G +G C C C+ G+C
Sbjct: 771 EVVC------THCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNC 824
Query: 456 DPITGDCI 463
DP++G C+
Sbjct: 825 DPLSGHCL 832
Score = 73.9 bits (180), Expect = 4e-13
Identities = 57/197 (28%), Positives = 77/197 (39%), Gaps = 42/197 (21%)
Query: 260 GSCFCNGHADQCIPV--HGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYND-RPW 316
GS AD+C+P H V V G+C C + C C P + D +P
Sbjct: 852 GSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG 911
Query: 317 EAADGKTGAPNECRTCKCN---GHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQR 373
CR+CKC+ D CH G C C+ GQ C R
Sbjct: 912 RG----------CRSCKCHPLGSQEDQCH-----------PKTGQCT-CRPGVTGQACDR 949
Query: 374 CKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDR 433
C+ GF+ FS C+ C C P+G+A + NG C C+PG G +CDR
Sbjct: 950 CQLGFFG-----FSIK-GCRACRCSPLGAASAQCHE-------NGTCVCRPGFEGYKCDR 996
Query: 434 CMVGYWGFGD-YGCRPC 449
C ++ D C+ C
Sbjct: 997 CHDNFFLTADGTHCQQC 1013
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 7/54 (12%)
Query: 420 CPCKPGVAGRRCDRCMVGY-----WGFGDYGCRPCDC--AGSCDPITGDCISSH 466
C C G G+ C+ C GY G C PC C G+CDP TG C+ SH
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSH 726
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 228 bits (580), Expect = 2e-59
Identities = 188/647 (29%), Positives = 275/647 (42%), Gaps = 110/647 (17%)
Query: 8 LLLWGCTVVAAGLSGVAGVSSRCE------KACNPRMGNLALGRKLWADTTCGQNATELY 61
LLL T+ AA G + C + C P + N ALGR++ A +TCG+ AT
Sbjct: 8 LLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATRA- 66
Query: 62 CFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDL 121
C+A+ P AH P+ + W+S E + R + + L
Sbjct: 67 ------------------CDASDPRRAHSPALLTSPGGTASPLCWRS-ESLPRAPLNVTL 107
Query: 122 EAE----FYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVK- 176
F + + F S PA++ L +SQD G++W P +F+++C +G
Sbjct: 108 TVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANG 167
Query: 177 -----KGAICTSKYSSPF--PCTGGEVIFKAL-SPPYDTENPYSAKVQEQLKITNLRVQL 228
A+C + +P P G + F S P + S +Q+ + T++RV +
Sbjct: 168 PAGPGPEALC---FPAPLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRV-V 223
Query: 229 LKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHM 288
L R S D+ + YA D V G C CNGHA +C+ + G H+
Sbjct: 224 LTRPSTAGDPRDMEAVVPY--SYAATDLQVGGRCKCNGHASRCL-------LDTQG--HL 272
Query: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 348
+ C C+H T G C C P Y DRPW+ A + + C C CNGHA C F++ ++
Sbjct: 273 I---CDCRHGTEGPDCGRCKPFYCDRPWQRATARES--HACLACSCNGHARRCRFNMELY 327
Query: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
SG RSGGVC +C+HNT G++C C+ GFYRD R S AC+ C CHPVG+A N
Sbjct: 328 RLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCN 387
Query: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTD 468
T G CPCK GV G C+RC GF C + PI G
Sbjct: 388 QTT------GQCPCKDGVTGLTCNRCAP---GFQQSRSPVAPCVKT--PIPG-------- 428
Query: 469 IDWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVL 528
D PV + + + A+G + + K FC K Y +
Sbjct: 429 -----PTEDSSPVQPQDCDS-HCKPARGSYRI--------------SLKKFC--KKDYAV 466
Query: 529 KIKI-LSAHDKGTHVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILNPGLEY 587
++ + +G V + V +S + + RG L+ + D C CP L PG Y
Sbjct: 467 QVAVGARGEARGAWTRFPVAVLAVFRSGEERARRGSSALWVPA-GDAACGCPRLLPGRRY 525
Query: 588 LV--------AGHEDIRTGKLIVNMKSFVQHWKPSLGRKVMDILKRE 626
L+ AG R LI S V W+ + R++ + +RE
Sbjct: 526 LLLGGGPGAAAGGAGGRGPGLIAARGSLVLPWRDAWTRRLRRLQRRE 572
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 209 bits (532), Expect = 6e-54
Identities = 165/525 (31%), Positives = 231/525 (44%), Gaps = 103/525 (19%)
Query: 2 GSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACN--------PRMGNLALGRKLWADTTC 53
G+ LLLL +++ GL GV + ++ P + NLA + + TC
Sbjct: 3 GAAGVLLLL----LLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATC 58
Query: 54 GQNATELYCFYSENTD-LTCRQPKCDKCN--AAYPHLAHLPSAMADSSFRFPRTWWQSAE 110
G+ E+YC E+ R P+C CN ++ P+ H + D TWWQS
Sbjct: 59 GEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQSPS 114
Query: 111 -----DVHREKIQLDLEAEFYFTHLIVMF-KSPRPAAMVLDRSQDFGKTWKPYKYFA--- 161
+ H I LDL+ F ++IV SPRP +L+RS D +KP++Y A
Sbjct: 115 IKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHAVTD 173
Query: 162 TNCSATFGL----------EDDVVKKGAICTSKYSSPFPCTGGEVIFKALS--PPYDTEN 209
T C + + +DD V ICTS YS P GE+ ++ P D +
Sbjct: 174 TECLTLYNIYPRTGPPSYAKDDEV----ICTSFYSKIHPLENGEIHISLINGRPSADDPS 229
Query: 210 PYSAKVQEQLKITNLRVQLLKRQSCPCQRNDL----NEEPQHFT-------HYAIYDFIV 258
P E L+ T+ R L+ Q DL +++P+ +Y++ D V
Sbjct: 230 P------ELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISV 283
Query: 259 KGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEA 318
G C C GHA C P+ P T +C C+HNT G C C P ++ +PW A
Sbjct: 284 GGMCICYGHARAC-------PLD-PATNK---SRCECEHNTCGDSCDQCCPGFHQKPWRA 332
Query: 319 ADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRS---------GGVCDDCQHNTEGQ 369
T EC C C+G A+ C++D NV A N S GGVC +C NT G
Sbjct: 333 GTFLT--KTECEACNCHGKAEECYYDENV--ARRNLSLNIRGKYIGGGVCINCTQNTAGI 388
Query: 370 YCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSN-------GDCPC 422
C+ C GF+R + P C+PC C P+GS N V D + G C C
Sbjct: 389 NCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGS----LNEVCVKDEKHARRGLAPGSCHC 444
Query: 423 KPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG----SCDPITGDCI 463
K G G CDRC GY G+ D C+ C+C+G + DP G CI
Sbjct: 445 KTGFGGVSCDRCARGYTGYPD--CKACNCSGLGSKNEDPCFGPCI 487
Score = 113 bits (283), Expect = 5e-25
Identities = 78/270 (28%), Positives = 114/270 (42%), Gaps = 64/270 (23%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CN + D IP G+ + G C+ CK T G +C+ CA Y +A D
Sbjct: 865 CQCNDNLDFSIP----------GSCDSLSGSCLICKPGTTGRYCELCADGYFG---DAVD 911
Query: 321 GKTGAPNECRTCKCNG---HADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
K C+ C+CN ++ CH G C+ C+ N +GQ C +CK G
Sbjct: 912 AKN-----CQPCRCNAGGSFSEVCHSQT-----------GQCE-CRANVQGQRCDKCKAG 954
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVG 437
+ + C PC+C+ GS +F +G C C+PGV G++CDRC G
Sbjct: 955 TFG-----LQSARGCVPCNCNSFGSK-------SFDCEESGQCWCQPGVTGKKCDRCAHG 1002
Query: 438 YWGFGDYGCRPCDCA---GSCDPITGDCISSHTDI----------DWYHEVPDFRPVHNK 484
Y+ F + GC C+C+ +CDP TG CI I W H + N
Sbjct: 1003 YFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNC 1062
Query: 485 SEPAWEWEDAQGFSALLHSGKCECKEQTLG 514
S + F +++G+C C + G
Sbjct: 1063 STVG-----SLDFQCNVNTGQCNCHPKFSG 1087
Score = 100 bits (248), Expect = 5e-21
Identities = 66/217 (30%), Positives = 92/217 (42%), Gaps = 52/217 (23%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C C GHA+ C V G+C+ CK +T G +C C P + P +
Sbjct: 757 CQCFGHAESC---------------DDVTGECLNCKDHTGGPYCDKCLPGFYGEPTK--- 798
Query: 321 GKTGAPNECRTCKC------NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRC 374
G +C+ C C N + TCH D ++ G +CD C G C+RC
Sbjct: 799 ---GTSEDCQPCACPLNIPSNNFSPTCHLDRSL--------GLICDGCPVGYTGPRCERC 847
Query: 375 KPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDR 433
G++ +P +C+PC C+ +P + CD +G C CKPG GR C+
Sbjct: 848 AEGYF---GQPSVPGGSCQPCQCNDNLDFSIPGS----CDSLSGSCLICKPGTTGRYCEL 900
Query: 434 CMVGYWG--FGDYGCRPCDC-AGS-----CDPITGDC 462
C GY+G C+PC C AG C TG C
Sbjct: 901 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQC 937
Score = 97.4 bits (241), Expect = 3e-20
Identities = 56/174 (32%), Positives = 75/174 (43%), Gaps = 34/174 (19%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CNGH+ C P C C+H+TAG C+ CA Y
Sbjct: 1420 CQCNGHSSLCDPETSI---------------CQNCQHHTAGDFCERCALGYYGIV----- 1459
Query: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
G PN+C+ C C + + +F + + C C EGQYC+RC PG+
Sbjct: 1460 --KGLPNDCQQCACPLISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPGYTG 1515
Query: 381 DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRC 434
P + +C+ C C P GS +P CDP G C C+PG GR+CD C
Sbjct: 1516 S---PGNPGGSCQECECDPYGSLPVP------CDPVTGFCTCRPGATGRKCDGC 1560
Score = 90.9 bits (224), Expect = 3e-18
Identities = 58/183 (31%), Positives = 87/183 (47%), Gaps = 27/183 (14%)
Query: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPN--ECRTCKCNGHADTCHFDVNVWE 349
KC C +G C+ C P + R G+T P C C+CNGH+ C + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFY-RLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETS--- 1434
Query: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
+C +CQH+T G +C+RC G+Y ++ P+ C+ C+C + S+ + S
Sbjct: 1435 --------ICQNCQHHTAGDFCERCALGYYGIVK---GLPNDCQQCACPLISSSNNFSPS 1483
Query: 410 VTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWGF-GDYG--CRPCDC--AGS----CDPIT 459
+ C C G G+ C+RC GY G G+ G C+ C+C GS CDP+T
Sbjct: 1484 CVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVT 1543
Query: 460 GDC 462
G C
Sbjct: 1544 GFC 1546
Score = 90.5 bits (223), Expect = 4e-18
Identities = 61/187 (32%), Positives = 86/187 (45%), Gaps = 39/187 (20%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C C GS C+ C P + G C C+C GHA++C DV
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGI------CEPCQCFGHAESCD-DVT------ 770
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVT- 411
G C +C+ +T G YC +C PGFY + + S + C+PC+C P+ +P+N+ +
Sbjct: 771 ----GECLNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCAC-PLN---IPSNNFSP 820
Query: 412 --FCDPSNG-DCP-CKPGVAGRRCDRCMVGYWGFGDY---GCRPCDC--------AGSCD 456
D S G C C G G RC+RC GY+G C+PC C GSCD
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCD 880
Query: 457 PITGDCI 463
++G C+
Sbjct: 881 SLSGSCL 887
Score = 72.8 bits (177), Expect = 9e-13
Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 41/181 (22%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C C+ G C CA Y + +G C C+C+ + C
Sbjct: 983 GQCWCQPGVTGKKCDRCAHGY----FNFQEGG------CTACECSHLGNNC--------- 1023
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
+ G C C NT G+ C +C P + S CK C+C VGS
Sbjct: 1024 --DPKTGRCI-CPPNTIGEKCSKCAPNTWGH-----SITTGCKACNCSTVGSLDFQ---- 1071
Query: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC------AGSCDPITGDCIS 464
C+ + G C C P +G +C C G+W + C CDC A +CD T C
Sbjct: 1072 --CNVNTGQCNCHPKFSGAKCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETKKCSC 1127
Query: 465 S 465
S
Sbjct: 1128 S 1128
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/170 (30%), Positives = 64/170 (37%), Gaps = 32/170 (18%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C+C NT G C CAP W + TG C+ C C+ + F NV
Sbjct: 1028 GRCICPPNTIGEKCSKCAP----NTWGHSI-TTG----CKACNCST-VGSLDFQCNV--- 1074
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
+ G C+ C G C C G + R C C C G+ +S
Sbjct: 1075 ----NTGQCN-CHPKFSGAKCTECSRGHWNYPR--------CNLCDCFLPGTDATTCDSE 1121
Query: 411 T---FCDPSNGDCPCKPGVAGRRCDRCMVGYWGF---GDYGCRPCDCAGS 454
T C G C CK V G CDRC G +G GC C C G+
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGT 1171
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/119 (30%), Positives = 47/119 (39%), Gaps = 20/119 (16%)
Query: 361 DCQHNTEGQYCQRCKPGFYR-----DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDP 415
DC G C+ C PGFYR R P C PC C+ S CDP
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS---------LCDP 1431
Query: 416 SNGDCP-CKPGVAGRRCDRCMVGYWGFG---DYGCRPCDC--AGSCDPITGDCISSHTD 468
C C+ AG C+RC +GY+G C+ C C S + + C++ D
Sbjct: 1432 ETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 9/53 (16%)
Query: 420 CPCKPGVAGRRCDRCM-----VGYWGFGDYGCRPCDCAG---SCDPITGDCIS 464
C C PG G C+ C V FG C PC C G SCD +TG+C++
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGI-CEPCQCFGHAESCDDVTGECLN 775
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 209 bits (532), Expect = 6e-54
Identities = 165/525 (31%), Positives = 231/525 (44%), Gaps = 103/525 (19%)
Query: 2 GSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACN--------PRMGNLALGRKLWADTTC 53
G+ LLLL +++ GL GV + ++ P + NLA + + TC
Sbjct: 3 GAAGVLLLL----LLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATC 58
Query: 54 GQNATELYCFYSENTD-LTCRQPKCDKCN--AAYPHLAHLPSAMADSSFRFPRTWWQSAE 110
G+ E+YC E+ R P+C CN ++ P+ H + D TWWQS
Sbjct: 59 GEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQSPS 114
Query: 111 -----DVHREKIQLDLEAEFYFTHLIVMF-KSPRPAAMVLDRSQDFGKTWKPYKYFA--- 161
+ H I LDL+ F ++IV SPRP +L+RS D +KP++Y A
Sbjct: 115 IKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHAVTD 173
Query: 162 TNCSATFGL----------EDDVVKKGAICTSKYSSPFPCTGGEVIFKALS--PPYDTEN 209
T C + + +DD V ICTS YS P GE+ ++ P D +
Sbjct: 174 TECLTLYNIYPRTGPPSYAKDDEV----ICTSFYSKIHPLENGEIHISLINGRPSADDPS 229
Query: 210 PYSAKVQEQLKITNLRVQLLKRQSCPCQRNDL----NEEPQHFT-------HYAIYDFIV 258
P E L+ T+ R L+ Q DL +++P+ +Y++ D V
Sbjct: 230 P------ELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISV 283
Query: 259 KGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEA 318
G C C GHA C P+ P T +C C+HNT G C C P ++ +PW A
Sbjct: 284 GGMCICYGHARAC-------PLD-PATNK---SRCECEHNTCGDSCDQCCPGFHQKPWRA 332
Query: 319 ADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRS---------GGVCDDCQHNTEGQ 369
T EC C C+G A+ C++D NV A N S GGVC +C NT G
Sbjct: 333 GTFLT--KTECEACNCHGKAEECYYDENV--ARRNLSLNIRGKYIGGGVCINCTQNTAGI 388
Query: 370 YCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSN-------GDCPC 422
C+ C GF+R + P C+PC C P+GS N V D + G C C
Sbjct: 389 NCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGS----LNEVCVKDEKHARRGLAPGSCHC 444
Query: 423 KPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG----SCDPITGDCI 463
K G G CDRC GY G+ D C+ C+C+G + DP G CI
Sbjct: 445 KTGFGGVSCDRCARGYTGYPD--CKACNCSGLGSKNEDPCFGPCI 487
Score = 113 bits (283), Expect = 5e-25
Identities = 78/270 (28%), Positives = 114/270 (42%), Gaps = 64/270 (23%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CN + D IP G+ + G C+ CK T G +C+ CA Y +A D
Sbjct: 865 CQCNDNLDFSIP----------GSCDSLSGSCLICKPGTTGRYCELCADGYFG---DAVD 911
Query: 321 GKTGAPNECRTCKCNG---HADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
K C+ C+CN ++ CH G C+ C+ N +GQ C +CK G
Sbjct: 912 AKN-----CQPCRCNAGGSFSEVCHSQT-----------GQCE-CRANVQGQRCDKCKAG 954
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVG 437
+ + C PC+C+ GS +F +G C C+PGV G++CDRC G
Sbjct: 955 TFG-----LQSARGCVPCNCNSFGSK-------SFDCEESGQCWCQPGVTGKKCDRCAHG 1002
Query: 438 YWGFGDYGCRPCDCA---GSCDPITGDCISSHTDI----------DWYHEVPDFRPVHNK 484
Y+ F + GC C+C+ +CDP TG CI I W H + N
Sbjct: 1003 YFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNC 1062
Query: 485 SEPAWEWEDAQGFSALLHSGKCECKEQTLG 514
S + F +++G+C C + G
Sbjct: 1063 STVG-----SLDFQCNVNTGQCNCHPKFSG 1087
Score = 100 bits (248), Expect = 5e-21
Identities = 66/217 (30%), Positives = 92/217 (42%), Gaps = 52/217 (23%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C C GHA+ C V G+C+ CK +T G +C C P + P +
Sbjct: 757 CQCFGHAESC---------------DDVTGECLNCKDHTGGPYCDKCLPGFYGEPTK--- 798
Query: 321 GKTGAPNECRTCKC------NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRC 374
G +C+ C C N + TCH D ++ G +CD C G C+RC
Sbjct: 799 ---GTSEDCQPCACPLNIPSNNFSPTCHLDRSL--------GLICDGCPVGYTGPRCERC 847
Query: 375 KPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDR 433
G++ +P +C+PC C+ +P + CD +G C CKPG GR C+
Sbjct: 848 AEGYF---GQPSVPGGSCQPCQCNDNLDFSIPGS----CDSLSGSCLICKPGTTGRYCEL 900
Query: 434 CMVGYWG--FGDYGCRPCDC-AGS-----CDPITGDC 462
C GY+G C+PC C AG C TG C
Sbjct: 901 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQC 937
Score = 97.4 bits (241), Expect = 3e-20
Identities = 56/174 (32%), Positives = 75/174 (43%), Gaps = 34/174 (19%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CNGH+ C P C C+H+TAG C+ CA Y
Sbjct: 1420 CQCNGHSSLCDPETSI---------------CQNCQHHTAGDFCERCALGYYGIV----- 1459
Query: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
G PN+C+ C C + + +F + + C C EGQYC+RC PG+
Sbjct: 1460 --KGLPNDCQQCACPLISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPGYTG 1515
Query: 381 DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRC 434
P + +C+ C C P GS +P CDP G C C+PG GR+CD C
Sbjct: 1516 S---PGNPGGSCQECECDPYGSLPVP------CDPVTGFCTCRPGATGRKCDGC 1560
Score = 90.9 bits (224), Expect = 3e-18
Identities = 58/183 (31%), Positives = 87/183 (47%), Gaps = 27/183 (14%)
Query: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPN--ECRTCKCNGHADTCHFDVNVWE 349
KC C +G C+ C P + R G+T P C C+CNGH+ C + +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFY-RLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETS--- 1434
Query: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
+C +CQH+T G +C+RC G+Y ++ P+ C+ C+C + S+ + S
Sbjct: 1435 --------ICQNCQHHTAGDFCERCALGYYGIVK---GLPNDCQQCACPLISSSNNFSPS 1483
Query: 410 VTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWGF-GDYG--CRPCDC--AGS----CDPIT 459
+ C C G G+ C+RC GY G G+ G C+ C+C GS CDP+T
Sbjct: 1484 CVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVT 1543
Query: 460 GDC 462
G C
Sbjct: 1544 GFC 1546
Score = 90.5 bits (223), Expect = 4e-18
Identities = 61/187 (32%), Positives = 86/187 (45%), Gaps = 39/187 (20%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C C GS C+ C P + G C C+C GHA++C DV
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGI------CEPCQCFGHAESCD-DVT------ 770
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVT- 411
G C +C+ +T G YC +C PGFY + + S + C+PC+C P+ +P+N+ +
Sbjct: 771 ----GECLNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCAC-PLN---IPSNNFSP 820
Query: 412 --FCDPSNG-DCP-CKPGVAGRRCDRCMVGYWGFGDY---GCRPCDC--------AGSCD 456
D S G C C G G RC+RC GY+G C+PC C GSCD
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCD 880
Query: 457 PITGDCI 463
++G C+
Sbjct: 881 SLSGSCL 887
Score = 72.8 bits (177), Expect = 9e-13
Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 41/181 (22%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C C+ G C CA Y + +G C C+C+ + C
Sbjct: 983 GQCWCQPGVTGKKCDRCAHGY----FNFQEGG------CTACECSHLGNNC--------- 1023
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
+ G C C NT G+ C +C P + S CK C+C VGS
Sbjct: 1024 --DPKTGRCI-CPPNTIGEKCSKCAPNTWGH-----SITTGCKACNCSTVGSLDFQ---- 1071
Query: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC------AGSCDPITGDCIS 464
C+ + G C C P +G +C C G+W + C CDC A +CD T C
Sbjct: 1072 --CNVNTGQCNCHPKFSGAKCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETKKCSC 1127
Query: 465 S 465
S
Sbjct: 1128 S 1128
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/170 (30%), Positives = 64/170 (37%), Gaps = 32/170 (18%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C+C NT G C CAP W + TG C+ C C+ + F NV
Sbjct: 1028 GRCICPPNTIGEKCSKCAP----NTWGHSI-TTG----CKACNCST-VGSLDFQCNV--- 1074
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
+ G C+ C G C C G + R C C C G+ +S
Sbjct: 1075 ----NTGQCN-CHPKFSGAKCTECSRGHWNYPR--------CNLCDCFLPGTDATTCDSE 1121
Query: 411 T---FCDPSNGDCPCKPGVAGRRCDRCMVGYWGF---GDYGCRPCDCAGS 454
T C G C CK V G CDRC G +G GC C C G+
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGT 1171
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/119 (30%), Positives = 47/119 (39%), Gaps = 20/119 (16%)
Query: 361 DCQHNTEGQYCQRCKPGFYR-----DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDP 415
DC G C+ C PGFYR R P C PC C+ S CDP
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS---------LCDP 1431
Query: 416 SNGDCP-CKPGVAGRRCDRCMVGYWGFG---DYGCRPCDC--AGSCDPITGDCISSHTD 468
C C+ AG C+RC +GY+G C+ C C S + + C++ D
Sbjct: 1432 ETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLD 1490
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 9/53 (16%)
Query: 420 CPCKPGVAGRRCDRCM-----VGYWGFGDYGCRPCDCAG---SCDPITGDCIS 464
C C PG G C+ C V FG C PC C G SCD +TG+C++
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGI-CEPCQCFGHAESCDDVTGECLN 775
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 205 bits (521), Expect = 1e-52
Identities = 149/489 (30%), Positives = 215/489 (43%), Gaps = 80/489 (16%)
Query: 26 VSSRC-EKACNPRMGNLALGRKLWADTTCGQNATELYCFYSENTD-LTCRQPKCDKC--N 81
V+++C ++ P + NLA + + TCG+ E++C E+ R P+C C N
Sbjct: 13 VAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGN 72
Query: 82 AAYPHLAHLPSAMADSSFRFPRTWWQS-----AEDVHREKIQLDLEAEFYFTHLIVMF-K 135
+A P H S D + WWQS + H I LDL F ++I+
Sbjct: 73 SANPRERHPISHAIDGT----NNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAAN 128
Query: 136 SPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKG---------AICTSKYS 186
+PRP +L+RS D G T+ P++Y+A + S + ++G ICTS YS
Sbjct: 129 APRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYS 187
Query: 187 SPFPCTGGEVIFKALS--PPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDL--- 241
P GE+ ++ P D +P + L+ T+ R L+ Q DL
Sbjct: 188 RLVPLEHGEIHTSLINGRPSADDLSP------KLLEFTSARYIRLRLQRIRTLNADLMTL 241
Query: 242 -NEEPQHFT-------HYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKC 293
+ EP+ +Y+I D V G C C GHA C P +C
Sbjct: 242 SHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSC-----------PWDETTKKLQC 290
Query: 294 MCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE---- 349
C+HNT G C C P Y+ +PW G + N C C C+ A C++D +V +
Sbjct: 291 QCEHNTCGESCNRCCPGYHQQPWRP--GTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 350 ---ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLP 406
A R GGVC +C NT G C+ C G+YR + + C+PC+C PVGS
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGS---- 404
Query: 407 ANSVTFCDPSN---------GDCPCKPGVAGRRCDRCMVGYWGFG---DYGCRPCDCAGS 454
+SV D + G CPCK G G +CDRC +GY + GC P A S
Sbjct: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSA-S 463
Query: 455 CDPITGDCI 463
+P TG C+
Sbjct: 464 DEPCTGPCV 472
Score = 122 bits (305), Expect = 1e-27
Identities = 85/284 (29%), Positives = 120/284 (42%), Gaps = 72/284 (25%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C C+G+ D P +A G V G+C+ C NT G+HC+ CA +
Sbjct: 849 CDCSGNVD---------PSEA-GHCDSVTGECLKCLGNTDGAHCERCA--------DGFY 890
Query: 321 GKTGAPNECRTCKCN---GHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
G CR C+C+ H+ CH + G+CD C+ N GQ C +C G
Sbjct: 891 GDAVTAKNCRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHG 938
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVG 437
+Y + C+PC+C GS ++ T G C C PGVAG+RCDRC G
Sbjct: 939 YYG-----LDSGHGCRPCNCSVAGSV---SDGCT----DEGQCHCVPGVAGKRCDRCAHG 986
Query: 438 YWGFGDYGCRPCDCA---GSCDPITGDCISS-HTDIDWYHEVPDFRPVHNKSEPAWEWED 493
++ + D C PCDC +CDP TG+C+ HT E D W ++
Sbjct: 987 FYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGH---------WGYDA 1037
Query: 494 AQGFSAL-------------LHSGKCECKEQTLGNAKAFCGMKY 524
G A + +G C+CK + G A C + Y
Sbjct: 1038 EVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY 1081
Score = 115 bits (288), Expect = 1e-25
Identities = 80/269 (29%), Positives = 103/269 (38%), Gaps = 91/269 (33%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C C+GHA +C VHG C+ C HNT G HC+ C P + P
Sbjct: 742 CECHGHAAEC----------------NVHGVCIACAHNTTGVHCEQCLPGFYGEP----- 780
Query: 321 GKTGAPNECRTCKC------NGHADTCHFD-----VNVW--------------------- 348
G P +C+ C C N + TCH + V W
Sbjct: 781 -SRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP 839
Query: 349 ----------EASGN---RSGGVCDD-------CQHNTEGQYCQRCKPGFYRDLRRPFSA 388
+ SGN G CD C NT+G +C+RC GFY D
Sbjct: 840 TVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDA----VT 895
Query: 389 PDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF-GDYGCR 447
C+ C CH GS C G C CKP V G++CD+C+ GY+G +GCR
Sbjct: 896 AKNCRACECHVKGS------HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCR 949
Query: 448 PCDCAGSCDPITGDCISSHTDIDWYHEVP 476
PC+C+ + G TD H VP
Sbjct: 950 PCNCS-----VAGSVSDGCTDEGQCHCVP 973
Score = 105 bits (263), Expect = 1e-22
Identities = 78/244 (31%), Positives = 105/244 (43%), Gaps = 45/244 (18%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
C C G+ C+ C Y DG C+ C+C+GHA C+
Sbjct: 709 CECPQGYTGTSCESCLSGYY-----RVDGILFG-GICQPCECHGHAAECNVH-------- 754
Query: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
GVC C HNT G +C++C PGFY + R P C+PC+C P+ + N
Sbjct: 755 ----GVCIACAHNTTGVHCEQCLPGFYGEPSR--GTPGDCQPCAC-PL--TIASNNFSPT 805
Query: 413 CDPSNGD---CP-CKPGVAGRRCDRCMVGYWG---FGDYGCRPCDC--------AGSCDP 457
C ++GD C C PG +G C+RC GY+G C PCDC AG CD
Sbjct: 806 CHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDS 865
Query: 458 ITGDCISSHTDIDWYH--EVPD---FRPVHNKSEPAWEWEDAQGFSALLH--SGKCECKE 510
+TG+C+ + D H D V K+ A E SA+ H +G C+CK
Sbjct: 866 VTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKP 925
Query: 511 QTLG 514
G
Sbjct: 926 NVTG 929
Score = 86.7 bits (213), Expect = 6e-17
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 35/174 (20%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CN H+D C P G KC+ C NTAG HC C Y +
Sbjct: 1403 CSCNNHSDTCDPNTG---------------KCLNCGDNTAGDHCDVCTSGYYGKV----- 1442
Query: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
TG+ ++C C C V E + CD C EG++C+RC +Y
Sbjct: 1443 --TGSASDCALCACPHSPPASFSPTCVLEGDHDFR---CDACLLGYEGKHCERCSSSYYG 1497
Query: 381 DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRC 434
+ + P + C+ C C+P GS CD ++G C C+ G +G RCD C
Sbjct: 1498 NPQTPGGS---CQKCDCNPHGSVHGD------CDRTSGQCVCRLGASGLRCDEC 1542
Score = 85.9 bits (211), Expect = 1e-16
Identities = 58/182 (31%), Positives = 73/182 (40%), Gaps = 25/182 (13%)
Query: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAP--NECRTCKCNGHADTCHFDVNVWEA 350
C+C T G CQ CAP Y+ A + P C C CN H+DTC D N
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--DPNT--- 1416
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
G C +C NT G +C C G+Y + SA D C C+C A V
Sbjct: 1417 ------GKCLNCGDNTAGDHCDVCTSGYYGKVTG--SASD-CALCACPHSPPASFSPTCV 1467
Query: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDC------AGSCDPITGD 461
D C G G+ C+RC Y+G C+ CDC G CD +G
Sbjct: 1468 LEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQ 1527
Query: 462 CI 463
C+
Sbjct: 1528 CV 1529
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/161 (31%), Positives = 66/161 (40%), Gaps = 35/161 (21%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
G+C C AG C CA + + DG C C C +TC +
Sbjct: 967 GQCHCVPGVAGKRCDRCAHGF----YAYQDGS------CTPCDCPHTQNTCDPET----- 1011
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
G C C +T+G C+ C+ G + + A C+ C+C VGS +
Sbjct: 1012 ------GECV-CPPHTQGVKCEECEDGHWG-----YDAEVGCQACNCSLVGS------TH 1053
Query: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
CD G C CK GR CD+C +GY F D C PCDC
Sbjct: 1054 HRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD--CVPCDC 1092
Score = 71.2 bits (173), Expect = 3e-12
Identities = 63/219 (28%), Positives = 84/219 (38%), Gaps = 54/219 (24%)
Query: 259 KGSCFC-----NGHADQCIPVHGF--------RPVKAPGTFHMVH---GKCMCKHNTAGS 302
+G C C D+C HGF P P T + G+C+C +T G
Sbjct: 966 EGQCHCVPGVAGKRCDRC--AHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGV 1023
Query: 303 HCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDC 362
C+ C D W D + G C+ C C+ T H R V C
Sbjct: 1024 KCEEC----EDGHW-GYDAEVG----CQACNCSLVGSTHH-----------RCDVVTGHC 1063
Query: 363 QHNTE--GQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN---SVTFCDPSN 417
Q ++ G+ C +C G YRD PD C PC C G++ N + C
Sbjct: 1064 QCKSKFGGRACDQCSLG-YRDF------PD-CVPCDCDLRGTSGDACNLEQGLCGCVEET 1115
Query: 418 GDCPCKPGVAGRRCDRCMVGYWGF---GDYGCRPCDCAG 453
G CPCK V G +C+ C G + GC PC C+G
Sbjct: 1116 GACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSG 1154
Score = 38.1 bits (87), Expect = 0.025
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 15/61 (24%)
Query: 419 DCPCKPGVAGRRCDRCMVGYW-----GFGDYG-------CRPCDC---AGSCDPITGDCI 463
+C C PG G C C GY D G C PC C + +CDP TG C+
Sbjct: 1361 NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
Query: 464 S 464
+
Sbjct: 1421 N 1421
Score = 36.6 bits (83), Expect = 0.072
Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 7/51 (13%)
Query: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTC 341
G C+CK N G C C P + + K P C C C G +D C
Sbjct: 469 GPCVCKENVEGKACDRCKPGFYNL-------KEKNPRGCSECFCFGVSDVC 512
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 197 bits (500), Expect = 3e-50
Identities = 131/429 (30%), Positives = 203/429 (47%), Gaps = 56/429 (13%)
Query: 117 IQLDLE-AEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLED--D 173
I +DLE ++ ++I+ F SP+P + + R ++ W+ ++YFA NC A FG+++ D
Sbjct: 371 ISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNGD 429
Query: 174 VVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYS-----AKVQEQLKITNLRVQL 228
+ K ++ + S+ P + G V F L+P + Y+ +QE +K T +R
Sbjct: 430 LEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF 489
Query: 229 LKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHM 288
+ +L +YA+ + + G C C+GHAD C +P +
Sbjct: 490 HGQYYTTETAVNLRHR-----YYAVDEITISGRCQCHGHADNCDTTS--QPYR------- 535
Query: 289 VHGKCMCKHN--TAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVN 346
C+C T G HC C PLYND+P+ D + A N C+ C+CN H+ +CH++++
Sbjct: 536 ----CLCSQESFTEGLHCDRCLPLYNDKPFRQGD-QVYAFN-CKPCQCNSHSKSCHYNIS 589
Query: 347 VWEASGNR---SGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSA 403
V GGVCDDC+HNT G+ C+ CK F+R + SA D CKPC C VG+
Sbjct: 590 VDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGT- 648
Query: 404 VLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDCAGS------ 454
N CD G C CK V+GR+C++C G++ + GC PC+C S
Sbjct: 649 ---RNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 455 --CDPITGDCISSHTDIDWYHEVPDFRPVHNKS------EPA-WEWEDAQGFSALLHSGK 505
C +G C I + +F +S EP + HSG+
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 506 CECKEQTLG 514
CECK++ G
Sbjct: 766 CECKKEAKG 774
Score = 87.0 bits (214), Expect = 5e-17
Identities = 60/188 (31%), Positives = 80/188 (42%), Gaps = 42/188 (22%)
Query: 289 VHGKCMCKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRTCKCN--GHAD---TCH 342
+ G+C CK + +G C C YN + + P+ C C CN G D TCH
Sbjct: 658 IGGQCNCKRHVSGRQCNQCQNGFYNLQELD--------PDGCSPCNCNTSGTVDGDITCH 709
Query: 343 FDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGS 402
++ G C C+ N G C C GF R F+ C+PC C+ GS
Sbjct: 710 -----------QNSGQCK-CKANVIGLRCDHCNFGF--KFLRSFNDV-GCEPCQCNLHGS 754
Query: 403 AVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC--AGS-----C 455
FC+P +G C CK G +CD C ++G C+ CDC AGS C
Sbjct: 755 VN------KFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808
Query: 456 DPITGDCI 463
+ TG CI
Sbjct: 809 NAKTGQCI 816
Score = 83.2 bits (204), Expect = 7e-16
Identities = 57/190 (30%), Positives = 77/190 (40%), Gaps = 40/190 (21%)
Query: 285 TFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFD 344
T H G+C CK N G C HC + + + G C C+CN H F
Sbjct: 707 TCHQNSGQCKCKANVIGLRCDHCNFGFK---FLRSFNDVG----CEPCQCNLHGSVNKFC 759
Query: 345 VNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR-DLRRPFSAPDACKPCSCHPVGSA 403
N G C+ C+ +G C C+ FY D+ CK C C GS
Sbjct: 760 --------NPHSGQCE-CKKEAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGS- 802
Query: 404 VLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF---GDYGCRPCDCAGS------ 454
LP T C+ G C CKP V GR+C++C+ G + + C PC+C +
Sbjct: 803 -LPG---TVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGS 858
Query: 455 --CDPITGDC 462
C+ TG C
Sbjct: 859 LLCNKSTGQC 868
Score = 77.4 bits (189), Expect = 4e-14
Identities = 72/258 (27%), Positives = 101/258 (39%), Gaps = 46/258 (17%)
Query: 283 PGTF-HMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNEC-RTCKCNGHADT 340
PGT + G+C+CK N G C C L + + P C +T NG
Sbjct: 804 PGTVCNAKTGQCICKPNVEGRQCNKC--LEGNFYLRQNNSFLCLPCNCDKTGTINGSL-L 860
Query: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
C N+S G C C+ G C +C+P Y F C+ C C +
Sbjct: 861 C-----------NKSTGQCP-CKLGVTGLRCNQCEPHRYNLTIDNFQH---CQMCECDSL 905
Query: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFGDYGCRPCDCAGS---- 454
G+ LP T CDP +G C C P GRRC++C G++ GC PC C +
Sbjct: 906 GT--LPG---TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN 960
Query: 455 --CDPITGDCISSHTDI---------DWYHEVPDFRPVHNKSEPA-WEWEDAQGFSALLH 502
C+ +TG C+ I D Y F P + +P A + L
Sbjct: 961 HICNSLTGQCVCQDASIAGQRCDQCKDHYF---GFDPQTGRCQPCNCHLSGALNETCHLV 1017
Query: 503 SGKCECKEQTLGNAKAFC 520
+G+C CK+ G+ C
Sbjct: 1018 TGQCFCKQFVTGSKCDAC 1035
Score = 77.0 bits (188), Expect = 5e-14
Identities = 75/279 (26%), Positives = 101/279 (36%), Gaps = 94/279 (33%)
Query: 263 FCNGHADQC--------------------IPVHGFRPV------KAPGTF-HMVHGKCMC 295
FCN H+ QC + V + PGT + G+C+C
Sbjct: 758 FCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCIC 817
Query: 296 KHNTAGSHCQHCAP----LYNDRPWEAAD---GKTGAPNECRTC---------------- 332
K N G C C L + + KTG N C
Sbjct: 818 KPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGL 877
Query: 333 KCN--------------GHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQYCQ 372
+CN H C D + G G +CD C N +G+ C
Sbjct: 878 RCNQCEPHRYNLTIDNFQHCQMCECD-----SLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 373 RCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCK-PGVAGRRC 431
+C+PGFY P +A C PCSCH G+ NS+T G C C+ +AG+RC
Sbjct: 933 QCQPGFYIS---PGNA-TGCLPCSCHTTGAVNHICNSLT------GQCVCQDASIAGQRC 982
Query: 432 DRCMVGYWGFGDY--GCRPCDCAGS------CDPITGDC 462
D+C Y+GF C+PC+C S C +TG C
Sbjct: 983 DQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQC 1021
Score = 59.3 bits (142), Expect = 1e-08
Identities = 47/157 (29%), Positives = 60/157 (38%), Gaps = 33/157 (21%)
Query: 283 PGTF-HMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTC 341
PGT + G+C+C N G C C P + P A TG C C C+
Sbjct: 909 PGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNA----TG----CLPCSCHTTGAVN 960
Query: 342 HFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKP---GFYRDLRRPFSAPDACKPCSCH 398
H N G C + GQ C +CK GF R C+PC+CH
Sbjct: 961 HI--------CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR-------CQPCNCH 1005
Query: 399 PVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCM 435
G+ + VT G C CK V G +CD C+
Sbjct: 1006 LSGALNETCHLVT------GQCFCKQFVTGSKCDACV 1036
Score = 33.1 bits (74), Expect = 0.79
Identities = 12/25 (48%), Positives = 14/25 (56%)
Query: 285 TFHMVHGKCMCKHNTAGSHCQHCAP 309
T H+V G+C CK GS C C P
Sbjct: 1013 TCHLVTGQCFCKQFVTGSKCDACVP 1037
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 197 bits (500), Expect = 3e-50
Identities = 131/429 (30%), Positives = 203/429 (47%), Gaps = 56/429 (13%)
Query: 117 IQLDLE-AEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLED--D 173
I +DLE ++ ++I+ F SP+P + + R ++ W+ ++YFA NC A FG+++ D
Sbjct: 371 ISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNGD 429
Query: 174 VVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYS-----AKVQEQLKITNLRVQL 228
+ K ++ + S+ P + G V F L+P + Y+ +QE +K T +R
Sbjct: 430 LEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF 489
Query: 229 LKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHM 288
+ +L +YA+ + + G C C+GHAD C +P +
Sbjct: 490 HGQYYTTETAVNLRHR-----YYAVDEITISGRCQCHGHADNCDTTS--QPYR------- 535
Query: 289 VHGKCMCKHN--TAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVN 346
C+C T G HC C PLYND+P+ D + A N C+ C+CN H+ +CH++++
Sbjct: 536 ----CLCSQESFTEGLHCDRCLPLYNDKPFRQGD-QVYAFN-CKPCQCNSHSKSCHYNIS 589
Query: 347 VWEASGNR---SGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSA 403
V GGVCDDC+HNT G+ C+ CK F+R + SA D CKPC C VG+
Sbjct: 590 VDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGT- 648
Query: 404 VLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDCAGS------ 454
N CD G C CK V+GR+C++C G++ + GC PC+C S
Sbjct: 649 ---RNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 455 --CDPITGDCISSHTDIDWYHEVPDFRPVHNKS------EPA-WEWEDAQGFSALLHSGK 505
C +G C I + +F +S EP + HSG+
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 506 CECKEQTLG 514
CECK++ G
Sbjct: 766 CECKKEAKG 774
Score = 87.0 bits (214), Expect = 5e-17
Identities = 60/188 (31%), Positives = 80/188 (42%), Gaps = 42/188 (22%)
Query: 289 VHGKCMCKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRTCKCN--GHAD---TCH 342
+ G+C CK + +G C C YN + + P+ C C CN G D TCH
Sbjct: 658 IGGQCNCKRHVSGRQCNQCQNGFYNLQELD--------PDGCSPCNCNTSGTVDGDITCH 709
Query: 343 FDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGS 402
++ G C C+ N G C C GF R F+ C+PC C+ GS
Sbjct: 710 -----------QNSGQCK-CKANVIGLRCDHCNFGF--KFLRSFNDV-GCEPCQCNLHGS 754
Query: 403 AVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC--AGS-----C 455
FC+P +G C CK G +CD C ++G C+ CDC AGS C
Sbjct: 755 VN------KFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808
Query: 456 DPITGDCI 463
+ TG CI
Sbjct: 809 NAKTGQCI 816
Score = 83.2 bits (204), Expect = 7e-16
Identities = 57/190 (30%), Positives = 77/190 (40%), Gaps = 40/190 (21%)
Query: 285 TFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFD 344
T H G+C CK N G C HC + + + G C C+CN H F
Sbjct: 707 TCHQNSGQCKCKANVIGLRCDHCNFGFK---FLRSFNDVG----CEPCQCNLHGSVNKFC 759
Query: 345 VNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR-DLRRPFSAPDACKPCSCHPVGSA 403
N G C+ C+ +G C C+ FY D+ CK C C GS
Sbjct: 760 --------NPHSGQCE-CKKEAKGLQCDTCRENFYGLDVTN-------CKACDCDTAGS- 802
Query: 404 VLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF---GDYGCRPCDCAGS------ 454
LP T C+ G C CKP V GR+C++C+ G + + C PC+C +
Sbjct: 803 -LPG---TVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGS 858
Query: 455 --CDPITGDC 462
C+ TG C
Sbjct: 859 LLCNKSTGQC 868
Score = 77.4 bits (189), Expect = 4e-14
Identities = 72/258 (27%), Positives = 101/258 (39%), Gaps = 46/258 (17%)
Query: 283 PGTF-HMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNEC-RTCKCNGHADT 340
PGT + G+C+CK N G C C L + + P C +T NG
Sbjct: 804 PGTVCNAKTGQCICKPNVEGRQCNKC--LEGNFYLRQNNSFLCLPCNCDKTGTINGSL-L 860
Query: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
C N+S G C C+ G C +C+P Y F C+ C C +
Sbjct: 861 C-----------NKSTGQCP-CKLGVTGLRCNQCEPHRYNLTIDNFQH---CQMCECDSL 905
Query: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFGDYGCRPCDCAGS---- 454
G+ LP T CDP +G C C P GRRC++C G++ GC PC C +
Sbjct: 906 GT--LPG---TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN 960
Query: 455 --CDPITGDCISSHTDI---------DWYHEVPDFRPVHNKSEPA-WEWEDAQGFSALLH 502
C+ +TG C+ I D Y F P + +P A + L
Sbjct: 961 HICNSLTGQCVCQDASIAGQRCDQCKDHYF---GFDPQTGRCQPCNCHLSGALNETCHLV 1017
Query: 503 SGKCECKEQTLGNAKAFC 520
+G+C CK+ G+ C
Sbjct: 1018 TGQCFCKQFVTGSKCDAC 1035
Score = 77.0 bits (188), Expect = 5e-14
Identities = 75/279 (26%), Positives = 101/279 (36%), Gaps = 94/279 (33%)
Query: 263 FCNGHADQC--------------------IPVHGFRPV------KAPGTF-HMVHGKCMC 295
FCN H+ QC + V + PGT + G+C+C
Sbjct: 758 FCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCIC 817
Query: 296 KHNTAGSHCQHCAP----LYNDRPWEAAD---GKTGAPNECRTC---------------- 332
K N G C C L + + KTG N C
Sbjct: 818 KPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGL 877
Query: 333 KCN--------------GHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQYCQ 372
+CN H C D + G G +CD C N +G+ C
Sbjct: 878 RCNQCEPHRYNLTIDNFQHCQMCECD-----SLGTLPGTICDPISGQCLCVPNRQGRRCN 932
Query: 373 RCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCK-PGVAGRRC 431
+C+PGFY P +A C PCSCH G+ NS+T G C C+ +AG+RC
Sbjct: 933 QCQPGFYIS---PGNA-TGCLPCSCHTTGAVNHICNSLT------GQCVCQDASIAGQRC 982
Query: 432 DRCMVGYWGFGDY--GCRPCDCAGS------CDPITGDC 462
D+C Y+GF C+PC+C S C +TG C
Sbjct: 983 DQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQC 1021
Score = 59.3 bits (142), Expect = 1e-08
Identities = 47/157 (29%), Positives = 60/157 (38%), Gaps = 33/157 (21%)
Query: 283 PGTF-HMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTC 341
PGT + G+C+C N G C C P + P A TG C C C+
Sbjct: 909 PGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNA----TG----CLPCSCHTTGAVN 960
Query: 342 HFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKP---GFYRDLRRPFSAPDACKPCSCH 398
H N G C + GQ C +CK GF R C+PC+CH
Sbjct: 961 HI--------CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR-------CQPCNCH 1005
Query: 399 PVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCM 435
G+ + VT G C CK V G +CD C+
Sbjct: 1006 LSGALNETCHLVT------GQCFCKQFVTGSKCDACV 1036
Score = 33.1 bits (74), Expect = 0.79
Identities = 12/25 (48%), Positives = 14/25 (56%)
Query: 285 TFHMVHGKCMCKHNTAGSHCQHCAP 309
T H+V G+C CK GS C C P
Sbjct: 1013 TCHLVTGQCFCKQFVTGSKCDACVP 1037
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 187 bits (476), Expect = 2e-47
Identities = 129/461 (27%), Positives = 211/461 (45%), Gaps = 91/461 (19%)
Query: 46 KLWADTTCGQNATELYCFYS---ENTDLTCRQPK-----------CD-KCNAAYPHLAHL 90
K+W C +T++ + + D+TC P C+ +C+A+ P LAH
Sbjct: 43 KVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHP 102
Query: 91 PSAMADSSFRFPRTWWQSAE-DVHREKIQLDLEAEFYFT-----HLIVMFKSPRPAAMVL 144
P M D R P T+WQSA + + +Q+++ + T ++++ F+S RP M+L
Sbjct: 103 PELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMIL 162
Query: 145 DRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGA-------ICTSKYSSPFPCTGGEVI 197
++S D+G+TW+PY+Y+AT+C F ++ VK + ICT +YS+ + +
Sbjct: 163 EKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIH 222
Query: 198 FK-----------------ALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
F+ +L DT + K+++ +T+LR++LL+ ++
Sbjct: 223 FEIKDRFAFFAGPRLRNMASLYGQLDT----TKKLRDFFTVTDLRIRLLRPAVGEIFVDE 278
Query: 241 LNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTA 300
L+ ++F YAI D V+G C CN HA C+ + C C+HNT
Sbjct: 279 LHLA-RYF--YAISDIKVRGRCKCNLHATVCV-------------YDNSKLTCECEHNTT 322
Query: 301 GSHCQHCAPLYNDRPWEAADG---KTGAPNEC-------RTCKCNGHADTCHFDVNVWEA 350
G C C Y RPW G N C C+C GH++ C + +++
Sbjct: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY-IDLLNT 381
Query: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
+C C+HNT GQ+C+ C+ G++R+ + C C C+P+GS N
Sbjct: 382 V------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGS 435
Query: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
FC+ CK G G +CD C+ G YGC+P C
Sbjct: 436 GFCE-------CKTGTTGPKCDECLPG--NSWHYGCQPNVC 467
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 162 bits (410), Expect = 9e-40
Identities = 141/464 (30%), Positives = 201/464 (43%), Gaps = 90/464 (19%)
Query: 33 ACNPRMGNLALGRKLWADT---TCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAH 89
AC P++ L K+ + TCG + E +C + EN L + C+A+ P LAH
Sbjct: 38 ACQPKVMRLKDYVKVKVEPSGITCG-DPPERFCSH-ENPYLCSNE-----CDASNPDLAH 90
Query: 90 LPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLIVM-FKSPRPAAMV 143
P M D T+WQS I L T +VM F+ RP MV
Sbjct: 91 PPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMV 150
Query: 144 LDRSQDFGKTWKPYKYFATNCSATFGLED----DVVKKGA---ICTSKYSS--------- 187
L++S D G+TW+PY+++A +C FG+ D+ A +CT +YS
Sbjct: 151 LEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKH 210
Query: 188 -PFPCTGGEVIFKALSPPYDTENPY----SAK-VQEQLKITNLRVQLLKRQ--SCPCQRN 239
F IF A + +N Y SAK ++E +T+LR++LL+ QR
Sbjct: 211 VRFEVRDRFAIF-AGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRE 269
Query: 240 DLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNT 299
+L + YAI + V G C CN HA+ C G +C C+HNT
Sbjct: 270 NLYKY-----FYAISNIEVIGRCKCNLHANLCSMREGSL-------------QCECEHNT 311
Query: 300 AGSHCQHCAPLYNDRPWEAADGKT---GAPNECRT------CKCNGHADTCHFD--VNVW 348
G C C + R W A G+PN C T C+C GH++ C + +NV
Sbjct: 312 TGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVV 371
Query: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
C C+HNT GQ+CQ C+ G+YR+ + C C+C+ +GS N
Sbjct: 372 ---------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN 422
Query: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCM-VGYWGFGDYGCRPCDC 451
FC+ C+ G AG +CD C+ YW GC P C
Sbjct: 423 ETGFCE-------CREGAAGPKCDDCLPTHYW---RQGCYPNVC 456
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 161 bits (407), Expect = 2e-39
Identities = 106/377 (28%), Positives = 168/377 (44%), Gaps = 67/377 (17%)
Query: 258 VKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWE 317
++G C C+GHA +C + P +C C+H+T G C+ C P + D PW
Sbjct: 153 LRGRCQCHGHAARCAA-----RARPP--------RCHCRHHTTGPGCESCRPSHRDWPWR 199
Query: 318 AADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
A + P+ C C CN HA C F+ ++ SG RSGGVC+ C+H+T G++C C+PG
Sbjct: 200 PATPRH--PHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPG 257
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVG 437
F+RD +P + AC+ C CHP+G+ + C+ ++G C CK GV G C+RC G
Sbjct: 258 FWRDPSQPIFSRRACRACQCHPIGA------TGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
Query: 438 YWGFGD--YGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQ 495
Y C+ A + T SS Y + D R VH
Sbjct: 312 YQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTR-VHM------------ 358
Query: 496 GFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGTHVE-VNVKIKKVLKS 554
+ + +C + +VL+ ++L++ G + + V++ V K
Sbjct: 359 -------------------SLRRYC--QQDHVLRAQVLASEAAGPAWQRLAVRVLAVYKQ 397
Query: 555 TKLKIFRGKRTLYPESWTDRG---CTCPILNPGLEYLVAGHE--DIRTGKLIVNMKSFVQ 609
+ RG + ++W R C C L PG +YL+ G D +LI++
Sbjct: 398 RAQPVRRGDQ----DAWVPRADLTCGCLRLQPGTDYLLLGSAVGDPDPTRLILDRHGLAL 453
Query: 610 HWKPSLGRKVMDILKRE 626
W+P R + + + E
Sbjct: 454 PWRPRWARPLKRLQQEE 470
>gi|164414437 netrin G1 isoform 2 [Homo sapiens]
Length = 480
Score = 120 bits (302), Expect = 3e-27
Identities = 88/316 (27%), Positives = 147/316 (46%), Gaps = 65/316 (20%)
Query: 46 KLWADTTCGQNATELYCFYS---ENTDLTCRQPK-----------CD-KCNAAYPHLAHL 90
K+W C +T++ + + D+TC P C+ +C+A+ P LAH
Sbjct: 43 KVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHP 102
Query: 91 PSAMADSSFRFPRTWWQSAE-DVHREKIQLDLEAEFYFT-----HLIVMFKSPRPAAMVL 144
P M D R P T+WQSA + + +Q+++ + T ++++ F+S RP M+L
Sbjct: 103 PELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMIL 162
Query: 145 DRSQDFGKTWKPYKYFATNCSATFGLEDDVVKK-------GAICTSKYSSPFPCTGGEVI 197
++S D+G+TW+PY+Y+AT+C F ++ VK ICT +YS+ + +
Sbjct: 163 EKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIH 222
Query: 198 FK-----------------ALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
F+ +L DT + K+++ +T+LR++LL+ ++
Sbjct: 223 FEIKDRFAFFAGPRLRNMASLYGQLDT----TKKLRDFFTVTDLRIRLLRPAVGEIFVDE 278
Query: 241 LNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTA 300
L+ ++F YAI D V+G C CN HA C+ + C C+HNT
Sbjct: 279 LH-LARYF--YAISDIKVRGRCKCNLHATVCV-------------YDNSKLTCECEHNTT 322
Query: 301 GSHCQHCAPLYNDRPW 316
G C C Y RPW
Sbjct: 323 GPDCGKCKKNYQGRPW 338
Score = 37.7 bits (86), Expect = 0.032
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 24/85 (28%)
Query: 332 CKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA 391
CKCN HA C +D + + +C+HNT G C +CK + RP+S
Sbjct: 297 CKCNLHATVCVYD----------NSKLTCECEHNTTGPDCGKCKKNYQ---GRPWS---- 339
Query: 392 CKPCSCHPVGSAVLPANSVTFCDPS 416
P S P+ P + C PS
Sbjct: 340 --PGSYLPI-----PKGTANTCIPS 357
>gi|54312078 netrin G1 isoform 3 [Homo sapiens]
Length = 438
Score = 120 bits (302), Expect = 3e-27
Identities = 88/316 (27%), Positives = 147/316 (46%), Gaps = 65/316 (20%)
Query: 46 KLWADTTCGQNATELYCFYS---ENTDLTCRQPK-----------CD-KCNAAYPHLAHL 90
K+W C +T++ + + D+TC P C+ +C+A+ P LAH
Sbjct: 43 KVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHP 102
Query: 91 PSAMADSSFRFPRTWWQSAE-DVHREKIQLDLEAEFYFT-----HLIVMFKSPRPAAMVL 144
P M D R P T+WQSA + + +Q+++ + T ++++ F+S RP M+L
Sbjct: 103 PELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMIL 162
Query: 145 DRSQDFGKTWKPYKYFATNCSATFGLEDDVVKK-------GAICTSKYSSPFPCTGGEVI 197
++S D+G+TW+PY+Y+AT+C F ++ VK ICT +YS+ + +
Sbjct: 163 EKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIH 222
Query: 198 FK-----------------ALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
F+ +L DT + K+++ +T+LR++LL+ ++
Sbjct: 223 FEIKDRFAFFAGPRLRNMASLYGQLDT----TKKLRDFFTVTDLRIRLLRPAVGEIFVDE 278
Query: 241 LNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTA 300
L+ ++F YAI D V+G C CN HA C+ + C C+HNT
Sbjct: 279 LH-LARYF--YAISDIKVRGRCKCNLHATVCV-------------YDNSKLTCECEHNTT 322
Query: 301 GSHCQHCAPLYNDRPW 316
G C C Y RPW
Sbjct: 323 GPDCGKCKKNYQGRPW 338
Score = 43.9 bits (102), Expect = 4e-04
Identities = 40/149 (26%), Positives = 55/149 (36%), Gaps = 41/149 (27%)
Query: 332 CKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCK---------PGFYRDL 382
CKCN HA C +D + + +C+HNT G C +CK PG Y L
Sbjct: 297 CKCNLHATVCVYD----------NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY--L 344
Query: 383 RRPFSAPDACKPCSCHPVGSAVLPANSVTFCD-----PSNGDCPCKPGVAGRRCDRCMVG 437
P + C P S +G+ V N + C +N C C G C++
Sbjct: 345 PIPKGTANTCIP-SISSIGTNVCD-NELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR-- 400
Query: 438 YWGFGDYGCRPCDCAGSCDPITGDCISSH 466
C+ AGSC +G H
Sbjct: 401 -----------CEEAGSCGSDSGQGAPPH 418
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 105 bits (261), Expect = 2e-22
Identities = 60/171 (35%), Positives = 81/171 (47%), Gaps = 40/171 (23%)
Query: 305 QHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQH 364
Q C+P Y D K C C CNGH++ C G+C +CQH
Sbjct: 57 QGCSPGYY------RDHKGLYTGRCVPCNCNGHSNQCQ-----------DGSGICVNCQH 99
Query: 365 NTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGD--CPC 422
NT G++C+RC+ G+Y + + +C+ C C S T C + GD C C
Sbjct: 100 NTAGEHCERCQEGYYGN-----AVHGSCRACPCPHTNS------FATGCVVNGGDVRCSC 148
Query: 423 KPGVAGRRCDRCMVGYWG----FGDYGCRPCDC-----AGSCDPITGDCIS 464
K G G +C+RC GY+G FG C+PC C GSC P+TGDCI+
Sbjct: 149 KAGYTGTQCERCAPGYFGNPQKFGG-SCQPCSCNSNGQLGSCHPLTGDCIN 198
Score = 70.9 bits (172), Expect = 3e-12
Identities = 51/180 (28%), Positives = 66/180 (36%), Gaps = 51/180 (28%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CNGH++QC G C+ C+HNTAG HC+ C Y
Sbjct: 78 CNCNGHSNQCQDGSGI---------------CVNCQHNTAGEHCERCQEGYYG------- 115
Query: 321 GKTGAPNECRTCKC---NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
CR C C N A C + G V C+ G C+RC PG
Sbjct: 116 --NAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPG 163
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC---PCKPGVAGRRCDRC 434
++ + P +C+PCSC+ G + C P GDC K CD C
Sbjct: 164 YFGN---PQKFGGSCQPCSCNSNG-------QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 105 bits (261), Expect = 2e-22
Identities = 60/171 (35%), Positives = 81/171 (47%), Gaps = 40/171 (23%)
Query: 305 QHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQH 364
Q C+P Y D K C C CNGH++ C G+C +CQH
Sbjct: 57 QGCSPGYY------RDHKGLYTGRCVPCNCNGHSNQCQ-----------DGSGICVNCQH 99
Query: 365 NTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGD--CPC 422
NT G++C+RC+ G+Y + + +C+ C C S T C + GD C C
Sbjct: 100 NTAGEHCERCQEGYYGN-----AVHGSCRACPCPHTNS------FATGCVVNGGDVRCSC 148
Query: 423 KPGVAGRRCDRCMVGYWG----FGDYGCRPCDC-----AGSCDPITGDCIS 464
K G G +C+RC GY+G FG C+PC C GSC P+TGDCI+
Sbjct: 149 KAGYTGTQCERCAPGYFGNPQKFGG-SCQPCSCNSNGQLGSCHPLTGDCIN 198
Score = 70.9 bits (172), Expect = 3e-12
Identities = 51/180 (28%), Positives = 66/180 (36%), Gaps = 51/180 (28%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
C CNGH++QC G C+ C+HNTAG HC+ C Y
Sbjct: 78 CNCNGHSNQCQDGSGI---------------CVNCQHNTAGEHCERCQEGYYG------- 115
Query: 321 GKTGAPNECRTCKC---NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
CR C C N A C + G V C+ G C+RC PG
Sbjct: 116 --NAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPG 163
Query: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC---PCKPGVAGRRCDRC 434
++ + P +C+PCSC+ G + C P GDC K CD C
Sbjct: 164 YFGN---PQKFGGSCQPCSCNSNG-------QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 102 bits (255), Expect = 8e-22
Identities = 73/249 (29%), Positives = 100/249 (40%), Gaps = 47/249 (18%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
C CNG++++C+ G+ + VH C+ NT G HC+ C Y D
Sbjct: 82 CDCNGNSNECLD----------GSGYCVH----CQRNTTGEHCEKCLDGY------IGDS 121
Query: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
GAP C+ C C H N E+ ++G V C N G C+RC PG+Y +
Sbjct: 122 IRGAPQFCQPCPC----PLPHL-ANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440
P CK C C P CD G C C G +C+RC GY+G
Sbjct: 177 ---PLLIGSTCKKCDCSGNSD---PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG 230
Query: 441 FGDY--GCRPCDCAGS-CDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGF 497
C C+C G CD +TG+C+ F P + W+ DA
Sbjct: 231 DARIAKNCAVCNCGGGPCDSVTGECLEE-----------GFEPPTGCDKCVWDLTDALRL 279
Query: 498 SAL-LHSGK 505
+AL + GK
Sbjct: 280 AALSIEEGK 288
Score = 86.7 bits (213), Expect = 6e-17
Identities = 52/151 (34%), Positives = 67/151 (44%), Gaps = 35/151 (23%)
Query: 328 ECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
EC C CNG+++ C G C CQ NT G++C++C G+ D R
Sbjct: 78 ECVPCDCNGNSNECL-----------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
Query: 388 APDACKPCSCHPVGSAVLP--ANSVTFCDPSNG--DCPCKPGVAGRRCDRCMVGYWG--- 440
AP C+PC C LP AN C NG C C AG C+RC GY+G
Sbjct: 125 APQFCQPCPC------PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Query: 441 FGDYGCRPCDCAGS---------CDPITGDC 462
C+ CDC+G+ CD +TG C
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 102 bits (255), Expect = 8e-22
Identities = 73/249 (29%), Positives = 100/249 (40%), Gaps = 47/249 (18%)
Query: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
C CNG++++C+ G+ + VH C+ NT G HC+ C Y D
Sbjct: 82 CDCNGNSNECLD----------GSGYCVH----CQRNTTGEHCEKCLDGY------IGDS 121
Query: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
GAP C+ C C H N E+ ++G V C N G C+RC PG+Y +
Sbjct: 122 IRGAPQFCQPCPC----PLPHL-ANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440
P CK C C P CD G C C G +C+RC GY+G
Sbjct: 177 ---PLLIGSTCKKCDCSGNSD---PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG 230
Query: 441 FGDY--GCRPCDCAGS-CDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGF 497
C C+C G CD +TG+C+ F P + W+ DA
Sbjct: 231 DARIAKNCAVCNCGGGPCDSVTGECLEE-----------GFEPPTGCDKCVWDLTDALRL 279
Query: 498 SAL-LHSGK 505
+AL + GK
Sbjct: 280 AALSIEEGK 288
Score = 86.7 bits (213), Expect = 6e-17
Identities = 52/151 (34%), Positives = 67/151 (44%), Gaps = 35/151 (23%)
Query: 328 ECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
EC C CNG+++ C G C CQ NT G++C++C G+ D R
Sbjct: 78 ECVPCDCNGNSNECL-----------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
Query: 388 APDACKPCSCHPVGSAVLP--ANSVTFCDPSNG--DCPCKPGVAGRRCDRCMVGYWG--- 440
AP C+PC C LP AN C NG C C AG C+RC GY+G
Sbjct: 125 APQFCQPCPC------PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Query: 441 FGDYGCRPCDCAGS---------CDPITGDC 462
C+ CDC+G+ CD +TG C
Sbjct: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 102 bits (254), Expect = 1e-21
Identities = 61/144 (42%), Positives = 74/144 (51%), Gaps = 20/144 (13%)
Query: 325 APNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRR 384
A + C CNG + C FD + +GN G C +C NT+G +C++CK GFYR R
Sbjct: 21 ATSRREVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
Query: 385 PFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY 444
D C PC+C+ GS L A CD S G C CKPGV G RCDRC+ G+ D
Sbjct: 79 -----DRCLPCNCNSKGS--LSAR----CDNS-GRCSCKPGVTGARCDRCLPGFHMLTDA 126
Query: 445 GC----RPCDCAGSCDP--ITGDC 462
GC R D CDP I G C
Sbjct: 127 GCTQDQRLLDSKCDCDPAGIAGPC 150
Score = 89.7 bits (221), Expect = 7e-18
Identities = 60/180 (33%), Positives = 79/180 (43%), Gaps = 33/180 (18%)
Query: 273 PVH-GFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRT 331
P H GF P T +V C G+ C+ CA Y P+ G+ G C+
Sbjct: 463 PCHNGFSCSVMPETEEVVCNNC--PPGVTGARCELCADGYFGDPF----GEHGPVRPCQP 516
Query: 332 CKCNGHADTCHFDVNVWEASGN--RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAP 389
C+CN + D ASGN R G C C HNT G YC +CK G++ D P A
Sbjct: 517 CQCNNNVDP--------SASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPA- 567
Query: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449
D C+ C+C+P+GS + S+G C CKPG G C+ G + C C
Sbjct: 568 DKCRACNCNPMGSEPVGCR-------SDGTCVCKPGFGGPNCEH--------GAFSCPAC 612
Score = 88.6 bits (218), Expect = 2e-17
Identities = 61/193 (31%), Positives = 77/193 (39%), Gaps = 55/193 (28%)
Query: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEAS 351
+C+C G CQ CA Y + + G C C C G
Sbjct: 381 QCICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQG--------------- 420
Query: 352 GNRSGGVCD----DCQHNTEGQ--YCQRCKPGFYRDLRRPFSAPDACKPCSCH-PVGSAV 404
GG CD DC E C C GFY D P S CKPC CH +V
Sbjct: 421 ----GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS----CKPCPCHNGFSCSV 472
Query: 405 LPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG--FGDYG----CRPCDC------- 451
+P C+ C PGV G RC+ C GY+G FG++G C+PC C
Sbjct: 473 MPETEEVVCN------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPS 526
Query: 452 -AGSCDPITGDCI 463
+G+CD +TG C+
Sbjct: 527 ASGNCDRLTGRCL 539
Score = 44.7 bits (104), Expect = 3e-04
Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 420 CPCKPGVAGRRCDRCMVGYWG----FGDYG-CRPCDC--AGSCDPITGDCISSHTDID 470
C C G G+ C C GY G +G C PC+C G+CDP TGDC S + D
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 102 bits (254), Expect = 1e-21
Identities = 61/144 (42%), Positives = 74/144 (51%), Gaps = 20/144 (13%)
Query: 325 APNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRR 384
A + C CNG + C FD + +GN G C +C NT+G +C++CK GFYR R
Sbjct: 21 ATSRREVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
Query: 385 PFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY 444
D C PC+C+ GS L A CD S G C CKPGV G RCDRC+ G+ D
Sbjct: 79 -----DRCLPCNCNSKGS--LSAR----CDNS-GRCSCKPGVTGARCDRCLPGFHMLTDA 126
Query: 445 GC----RPCDCAGSCDP--ITGDC 462
GC R D CDP I G C
Sbjct: 127 GCTQDQRLLDSKCDCDPAGIAGPC 150
Score = 89.7 bits (221), Expect = 7e-18
Identities = 60/180 (33%), Positives = 79/180 (43%), Gaps = 33/180 (18%)
Query: 273 PVH-GFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRT 331
P H GF P T +V C G+ C+ CA Y P+ G+ G C+
Sbjct: 463 PCHNGFSCSVMPETEEVVCNNC--PPGVTGARCELCADGYFGDPF----GEHGPVRPCQP 516
Query: 332 CKCNGHADTCHFDVNVWEASGN--RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAP 389
C+CN + D ASGN R G C C HNT G YC +CK G++ D P A
Sbjct: 517 CQCNNNVDP--------SASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPA- 567
Query: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449
D C+ C+C+P+GS + S+G C CKPG G C+ G + C C
Sbjct: 568 DKCRACNCNPMGSEPVGCR-------SDGTCVCKPGFGGPNCEH--------GAFSCPAC 612
Score = 88.6 bits (218), Expect = 2e-17
Identities = 61/193 (31%), Positives = 77/193 (39%), Gaps = 55/193 (28%)
Query: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEAS 351
+C+C G CQ CA Y + + G C C C G
Sbjct: 381 QCICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQG--------------- 420
Query: 352 GNRSGGVCD----DCQHNTEGQ--YCQRCKPGFYRDLRRPFSAPDACKPCSCH-PVGSAV 404
GG CD DC E C C GFY D P S CKPC CH +V
Sbjct: 421 ----GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS----CKPCPCHNGFSCSV 472
Query: 405 LPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG--FGDYG----CRPCDC------- 451
+P C+ C PGV G RC+ C GY+G FG++G C+PC C
Sbjct: 473 MPETEEVVCN------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPS 526
Query: 452 -AGSCDPITGDCI 463
+G+CD +TG C+
Sbjct: 527 ASGNCDRLTGRCL 539
Score = 44.7 bits (104), Expect = 3e-04
Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 420 CPCKPGVAGRRCDRCMVGYWG----FGDYG-CRPCDC--AGSCDPITGDCISSHTDID 470
C C G G+ C C GY G +G C PC+C G+CDP TGDC S + D
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.470
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,170,194
Number of Sequences: 37866
Number of extensions: 1404830
Number of successful extensions: 5578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 141
Number of HSP's that attempted gapping in prelim test: 3600
Number of HSP's gapped (non-prelim): 848
length of query: 628
length of database: 18,247,518
effective HSP length: 108
effective length of query: 520
effective length of database: 14,157,990
effective search space: 7362154800
effective search space used: 7362154800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.