Search of human proteins with 9257192

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9257192 adducin 2 isoform a [Homo sapiens]
         (726 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9257192 adducin 2 isoform a [Homo sapiens]                        1442   0.0  
gi|9257190 adducin 2 isoform e [Homo sapiens]                        1166   0.0  
gi|89276787 adducin 2 isoform b [Homo sapiens]                       1068   0.0  
gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]                 762   0.0  
gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]                 728   0.0  
gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]                728   0.0  
gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]                633   0.0  
gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]                617   e-177
gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]                590   e-168
gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]                575   e-164
gi|9257180 adducin 2 isoform c [Homo sapiens]                         452   e-127
gi|89276790 adducin 2 isoform d [Homo sapiens]                        374   e-103
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     62   2e-09
gi|157738619 smoothelin-like 1 [Homo sapiens]                          50   6e-06
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    50   7e-06
gi|168229156 NFKB activating protein [Homo sapiens]                    50   7e-06
gi|110349719 titin isoform N2-A [Homo sapiens]                         50   1e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    50   1e-05
gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens]         49   2e-05
gi|42518068 trans-golgi network protein 2 [Homo sapiens]               49   2e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   6e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   6e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   6e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   6e-05
gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]           47   6e-05
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    47   6e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    47   8e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       46   1e-04
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           46   1e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           46   1e-04

>gi|9257192 adducin 2 isoform a [Homo sapiens]
          Length = 726

 Score = 1442 bits (3734), Expect = 0.0
 Identities = 726/726 (100%), Positives = 726/726 (100%)

Query: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
           MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60

Query: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
           PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120

Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
           ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180

Query: 181 TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK 240
           TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK
Sbjct: 181 TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK 240

Query: 241 WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE 300
           WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE
Sbjct: 241 WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE 300

Query: 301 EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL 360
           EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL
Sbjct: 301 EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL 360

Query: 361 GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR 420
           GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR
Sbjct: 361 GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR 420

Query: 421 QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE 480
           QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE
Sbjct: 421 QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE 480

Query: 481 NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSK 540
           NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSK
Sbjct: 481 NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSK 540

Query: 541 GDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPAS 600
           GDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPAS
Sbjct: 541 GDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPAS 600

Query: 601 PVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEE 660
           PVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEE
Sbjct: 601 PVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEE 660

Query: 661 ILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKK 720
           ILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKK
Sbjct: 661 ILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKK 720

Query: 721 KEKVES 726
           KEKVES
Sbjct: 721 KEKVES 726


>gi|9257190 adducin 2 isoform e [Homo sapiens]
          Length = 643

 Score = 1166 bits (3016), Expect = 0.0
 Identities = 587/593 (98%), Positives = 587/593 (98%), Gaps = 4/593 (0%)

Query: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
           MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60

Query: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
           PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120

Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
           ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180

Query: 181 TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK 240
           TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK
Sbjct: 181 TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK 240

Query: 241 WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE 300
           WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE
Sbjct: 241 WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE 300

Query: 301 EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL 360
           EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL
Sbjct: 301 EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL 360

Query: 361 GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR 420
           GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR
Sbjct: 361 GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR 420

Query: 421 QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE 480
           QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE
Sbjct: 421 QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE 480

Query: 481 NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSK 540
           NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSK
Sbjct: 481 NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSK 540

Query: 541 GDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPE-EPGS 592
           GDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELD   ET  E EPGS
Sbjct: 541 GDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELD---ETGQEREPGS 590


>gi|89276787 adducin 2 isoform b [Homo sapiens]
          Length = 559

 Score = 1068 bits (2761), Expect = 0.0
 Identities = 535/543 (98%), Positives = 536/543 (98%), Gaps = 1/543 (0%)

Query: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
           MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60

Query: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
           PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120

Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
           ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180

Query: 181 TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK 240
           TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK
Sbjct: 181 TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK 240

Query: 241 WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE 300
           WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE
Sbjct: 241 WGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE 300

Query: 301 EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL 360
           EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL
Sbjct: 301 EAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL 360

Query: 361 GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR 420
           GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR
Sbjct: 361 GEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR 420

Query: 421 QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE 480
           QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE
Sbjct: 421 QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE 480

Query: 481 NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSK 540
           NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP  E +L   
Sbjct: 481 NPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP-VEQRLPLT 539

Query: 541 GDE 543
           G E
Sbjct: 540 GGE 542


>gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]
          Length = 706

 Score =  762 bits (1967), Expect = 0.0
 Identities = 399/733 (54%), Positives = 532/733 (72%), Gaps = 34/733 (4%)

Query: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120

Query: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180

Query: 177 CSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAV 236
            SE TAS+L+KVNI+GEVV++GS+   +D TGF  H+AIY+ RPDV+C+IH+HT ATAAV
Sbjct: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240

Query: 237 SAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALG 296
           S+MK G+LP+S  +LL+GD+AYYD+ G +E++ +RI LQK LGP+CK+LVLRNHGVVALG
Sbjct: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300

Query: 297 DTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHR--PHEVGSVQWAGSTFGP 354
           +T+EEAF+ IF++Q ACEIQV AL+ AGGV+NL +L+ +K++   + V +    G   G 
Sbjct: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360

Query: 355 MQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGA 414
            QK ++GE EFE LMR LDNLGYRTGY YRHP ++EK +HKS+VEIPATVTAF FE+D  
Sbjct: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420

Query: 415 PVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSG 474
           P+  L+  AQ+QQ+EKTRWLN+PNTY++VNV +E +    SPR K TWMKA++  K S G
Sbjct: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480

Query: 475 MPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTE 534
            PI+IE+PNQFVPL T+P EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K   PST 
Sbjct: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST- 537

Query: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLEL-DGEKETAPEEPGSP 593
              M   D+   D      PNPFS LT+ ELEEYK+ +ERK+  L D E+E   ++  S 
Sbjct: 538 ---MQFEDD---DHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEDAEQELLSDDASS- 590

Query: 594 AKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGRE 653
                 S +QS     +T+SP   P K LEE  +    S  +   P       +VVNG++
Sbjct: 591 -----VSQIQS-----QTQSPQNVPEK-LEENHELFSKSFISMEVPV------MVVNGKD 633

Query: 654 EEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPS 713
           +    E+ L+K +S+++TS   +      K+       +SPEGSPSKSPSKKKKKFRTPS
Sbjct: 634 DMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPS 693

Query: 714 FLKKSKKKEKVES 726
           FLKK+KKKEKVE+
Sbjct: 694 FLKKNKKKEKVEA 706


>gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score =  728 bits (1879), Expect = 0.0
 Identities = 387/732 (52%), Positives = 508/732 (69%), Gaps = 64/732 (8%)

Query: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120

Query: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180

Query: 177 CSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAV 236
            SE TAS+L+KVNI+GEVV++GS+   +D TGF  H+AIY+ RPDV+C+IH+HT ATAAV
Sbjct: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240

Query: 237 SAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALG 296
           S+MK G+LP+S  +LL+GD+AYYD+ G +E++ +RI LQK LGP+CK+LVLRNHGVVALG
Sbjct: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300

Query: 297 DTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHR--PHEVGSVQWAGSTFGP 354
           +T+EEAF+ IF++Q ACEIQV AL+ AGGV+NL +L+ +K++   + V +    G   G 
Sbjct: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360

Query: 355 MQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGA 414
            QK ++GE EFE LMR LDNLGYRTGY YRHP ++EK +HKS+VEIPATVTAF FE+D  
Sbjct: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420

Query: 415 PVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSG 474
           P+  L+  AQ+QQ+EKTRWLN+PNTY++VNV +E +    SPR K TWMKA++  K S G
Sbjct: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480

Query: 475 MPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTE 534
            PI+IE+PNQFVPL T+P EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K   PST 
Sbjct: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST- 537

Query: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPA 594
              M   D+   D      PNPFS LT+ ELEEYK+ +ERK+  L+   E          
Sbjct: 538 ---MQFEDD---DHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELF-------- 583

Query: 595 KSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREE 654
            S     ++ P      K  +      L +   +  TS         T  E +       
Sbjct: 584 -SKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTS---------TTIENI------- 626

Query: 655 EQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSF 714
                EI  K               S +K E V    +SPEGSPSKSPSKKKKKFRTPSF
Sbjct: 627 -----EITIK---------------SPEKIEEV----LSPEGSPSKSPSKKKKKFRTPSF 662

Query: 715 LKKSKKKEKVES 726
           LKK+KKKEKVE+
Sbjct: 663 LKKNKKKEKVEA 674


>gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score =  728 bits (1879), Expect = 0.0
 Identities = 387/732 (52%), Positives = 508/732 (69%), Gaps = 64/732 (8%)

Query: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120

Query: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180

Query: 177 CSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAV 236
            SE TAS+L+KVNI+GEVV++GS+   +D TGF  H+AIY+ RPDV+C+IH+HT ATAAV
Sbjct: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240

Query: 237 SAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALG 296
           S+MK G+LP+S  +LL+GD+AYYD+ G +E++ +RI LQK LGP+CK+LVLRNHGVVALG
Sbjct: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300

Query: 297 DTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHR--PHEVGSVQWAGSTFGP 354
           +T+EEAF+ IF++Q ACEIQV AL+ AGGV+NL +L+ +K++   + V +    G   G 
Sbjct: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360

Query: 355 MQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGA 414
            QK ++GE EFE LMR LDNLGYRTGY YRHP ++EK +HKS+VEIPATVTAF FE+D  
Sbjct: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420

Query: 415 PVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSG 474
           P+  L+  AQ+QQ+EKTRWLN+PNTY++VNV +E +    SPR K TWMKA++  K S G
Sbjct: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480

Query: 475 MPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTE 534
            PI+IE+PNQFVPL T+P EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K   PST 
Sbjct: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST- 537

Query: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPA 594
              M   D+   D      PNPFS LT+ ELEEYK+ +ERK+  L+   E          
Sbjct: 538 ---MQFEDD---DHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELF-------- 583

Query: 595 KSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREE 654
            S     ++ P      K  +      L +   +  TS         T  E +       
Sbjct: 584 -SKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTS---------TTIENI------- 626

Query: 655 EQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSF 714
                EI  K               S +K E V    +SPEGSPSKSPSKKKKKFRTPSF
Sbjct: 627 -----EITIK---------------SPEKIEEV----LSPEGSPSKSPSKKKKKFRTPSF 662

Query: 715 LKKSKKKEKVES 726
           LKK+KKKEKVE+
Sbjct: 663 LKKNKKKEKVEA 674


>gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
          Length = 737

 Score =  633 bits (1632), Expect = 0.0
 Identities = 348/733 (47%), Positives = 476/733 (64%), Gaps = 32/733 (4%)

Query: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71

Query: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131

Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191

Query: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251

Query: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311

Query: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371

Query: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431

Query: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPI 477
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT W K D    S+S +  
Sbjct: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAV-- 485

Query: 478 RIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TE 534
               PN FVPL T+P+EV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S       T 
Sbjct: 486 ----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTA 541

Query: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPA 594
           S+ + + +         T PNPF+ LTD+ELEEY++EVERK+   +   + A E+     
Sbjct: 542 SKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSP 601

Query: 595 KSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP-ETTQPEGVVVNGRE 653
              PA P   P+   + +  LV    + ++    T         P E ++  G  +  +E
Sbjct: 602 PDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKE 661

Query: 654 EEQTAEEILSKGLSQMTTSADTD-----VDTSKDKTESVTSGPMSPEGSPSKSPSKKKKK 708
           EE       ++  ++ +     D      + +    E   +     +GSP KSPSKKKKK
Sbjct: 662 EEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKK 721

Query: 709 FRTPSFLKKSKKK 721
           FRTPSFLKKSKKK
Sbjct: 722 FRTPSFLKKSKKK 734


>gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
          Length = 768

 Score =  617 bits (1592), Expect = e-177
 Identities = 350/758 (46%), Positives = 479/758 (63%), Gaps = 51/758 (6%)

Query: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71

Query: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131

Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191

Query: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251

Query: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311

Query: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371

Query: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431

Query: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKT-TWMKADE------VEK 470
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT  W           ++ 
Sbjct: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQS 487

Query: 471 SSSG--MPIRIEN----------------PNQFVPLYTDPQEVLEMRNKIREQNRQDVKS 512
            SSG  +P  I N                PN FVPL T+P+EV EMRNKIREQN QD+K+
Sbjct: 488 LSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKT 547

Query: 513 AGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYK 569
           AGPQSQ+L  V+ ++S       T S+ + + +         T PNPF+ LTD+ELEEY+
Sbjct: 548 AGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYR 607

Query: 570 KEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKT 629
           +EVERK+   +   + A E+        PA P   P+   + +  LV    + ++    T
Sbjct: 608 REVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAAT 667

Query: 630 ETSKAATTEP-ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTD-----VDTSKDK 683
                    P E ++  G  +  +EEE       ++  ++ +     D      + +   
Sbjct: 668 FKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSA 727

Query: 684 TESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKK 721
            E   +     +GSP KSPSKKKKKFRTPSFLKKSKKK
Sbjct: 728 VEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765


>gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]
          Length = 631

 Score =  590 bits (1521), Expect = e-168
 Identities = 321/631 (50%), Positives = 429/631 (67%), Gaps = 37/631 (5%)

Query: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71

Query: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131

Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191

Query: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251

Query: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311

Query: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371

Query: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431

Query: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPI 477
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT W K D    S+S +  
Sbjct: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAV-- 485

Query: 478 RIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPS---TE 534
               PN FVPL T+P+EV EMRNKIREQN QD+K+AGPQSQ+L  V+ ++S       T 
Sbjct: 486 ----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTA 541

Query: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPA 594
           S+ + + +         T PNPF+ LTD+ELEEY++EVERK+    G +E   E      
Sbjct: 542 SKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQ---KGSEENLDEAREQKE 598

Query: 595 KSAPASPVQSPAKEAETKSPLVSPSKSLEEG 625
           KS P  P       A    P  +P K LEEG
Sbjct: 599 KSPPDQP-------AVPHPPPSTPIK-LEEG 621


>gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]
          Length = 662

 Score =  575 bits (1481), Expect = e-164
 Identities = 323/656 (49%), Positives = 432/656 (65%), Gaps = 56/656 (8%)

Query: 11  SPPP---PQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREEL 67
           SPPP   P  + YFDR  E++PEY+R RN A DLRQDFN+MEQKKRV+MILQSP+F EEL
Sbjct: 12  SPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEEL 71

Query: 68  EGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTS--------SMNVSMMTPINDLH 119
           E +IQEQ KKG N + + AL+QIADFM +    V+P +        +M++ M+TP+NDL 
Sbjct: 72  ESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLR 131

Query: 120 TADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSE 179
            +DS+   KGE+L+RCK+++ YRL DL+GW+QL   ++T RV+ EQ+HFLI P G+  SE
Sbjct: 132 GSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSE 191

Query: 180 VTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAM 239
           VTASSL+K+N+ G++V++GS+   V+  GF LHSAIYAARPDV+C++H+HTPA AAVSAM
Sbjct: 192 VTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAM 251

Query: 240 KWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTV 299
           K GLLP+S  AL +G++AY+D++G +  E +++ +QK LGP  K+L+LRNHG+V++G++V
Sbjct: 252 KCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESV 311

Query: 300 EEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSR 359
           EEAFY I +L  ACEIQV  L+SAGG +NL+LL  EK++          G   G   K +
Sbjct: 312 EEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQ 371

Query: 360 LGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDG--APVP 417
           +GE EFEALMRMLDNLGYRTGY YR+P ++EK+K  S+VE+PA+VT + F  DG      
Sbjct: 372 IGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCS 431

Query: 418 ALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKT-TWMKADE------VEK 470
            LR   QKQQ+EKTRWLN+     R + A E  ++  SP+ KT  W           ++ 
Sbjct: 432 PLRHSFQKQQREKTRWLNSG----RGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQS 487

Query: 471 SSSG--MPIRIEN----------------PNQFVPLYTDPQEVLEMRNKIREQNRQDVKS 512
            SSG  +P  I N                PN FVPL T+P+EV EMRNKIREQN QD+K+
Sbjct: 488 LSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKT 547

Query: 513 AGPQSQLLASVIAEKSRSPS---TESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYK 569
           AGPQSQ+L  V+ ++S       T S+ + + +         T PNPF+ LTD+ELEEY+
Sbjct: 548 AGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYR 607

Query: 570 KEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEG 625
           +EVERK+    G +E   E      KS P  P       A    P  +P K LEEG
Sbjct: 608 REVERKQ---KGSEENLDEAREQKEKSPPDQP-------AVPHPPPSTPIK-LEEG 652


>gi|9257180 adducin 2 isoform c [Homo sapiens]
          Length = 420

 Score =  452 bits (1162), Expect = e-127
 Identities = 244/294 (82%), Positives = 252/294 (85%), Gaps = 22/294 (7%)

Query: 433 WLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDP 492
           W    +TY+ + V+ E    + SP+     +   EV  SS                    
Sbjct: 149 WAQLSDTYVTLRVSKEQDHFLISPKG----VSCSEVTASSL------------------I 186

Query: 493 QEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 552
           +EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET
Sbjct: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246

Query: 553 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 612
           VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK
Sbjct: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306

Query: 613 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 672
           SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS
Sbjct: 307 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 366

Query: 673 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
           ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES
Sbjct: 367 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420



 Score =  374 bits (959), Expect = e-103
 Identities = 187/187 (100%), Positives = 187/187 (100%)

Query: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
           MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60

Query: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
           PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120

Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
           ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180

Query: 181 TASSLIK 187
           TASSLIK
Sbjct: 181 TASSLIK 187


>gi|89276790 adducin 2 isoform d [Homo sapiens]
          Length = 253

 Score =  374 bits (959), Expect = e-103
 Identities = 187/187 (100%), Positives = 187/187 (100%)

Query: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60
           MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS
Sbjct: 1   MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQS 60

Query: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120
           PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT
Sbjct: 61  PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHT 120

Query: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180
           ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
Sbjct: 121 ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV 180

Query: 181 TASSLIK 187
           TASSLIK
Sbjct: 181 TASSLIK 187



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 53/111 (47%), Positives = 62/111 (55%), Gaps = 23/111 (20%)

Query: 433 WLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDP 492
           W    +TY+ + V+ E    + SP+     +   EV  SS                    
Sbjct: 149 WAQLSDTYVTLRVSKEQDHFLISPKG----VSCSEVTASSL------------------I 186

Query: 493 QEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDE 543
           +EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP  E +L   G E
Sbjct: 187 KEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSP-VEQRLPLTGGE 236


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 64/228 (28%), Positives = 98/228 (42%), Gaps = 22/228 (9%)

Query: 511 KSAGPQSQLLASVIAEKSRSPS---------TESQLMSKGDEDTKDDSEETVPNPFSQLT 561
           ++A P+ +   S + E+++SP+          +S    K  E  K  ++E   +P  +  
Sbjct: 508 EAASPEKE-AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP-PEAK 565

Query: 562 DQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKE-----AETKSPLV 616
             E EE K   E K  E    K  A EE  SPA++      +SP KE     AE KSP+ 
Sbjct: 566 SPEKEEAKSPAEVKSPE--KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK 623

Query: 617 SPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILS--KGLSQMTTSAD 674
             +KS  E  K  E +K+ T E E   PE      +EE ++ E+  S  K  ++    A 
Sbjct: 624 EEAKSPAE-VKSPEKAKSPTKE-EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681

Query: 675 TDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE 722
           + V       E   S       SP K+ S  K++ ++P   K   K+E
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 729



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 68/328 (20%), Positives = 135/328 (41%), Gaps = 35/328 (10%)

Query: 388 VQEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVAD 447
           V+E+ K  +EV+ P    +   EE  +P     + A+  +KE+ +   +P          
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSP-----EKAKSPEKEEAK---SPE-----KAKS 668

Query: 448 EVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE--NPNQFV-PLYTDPQEVLEMRNKIRE 504
            V+    SP    + +KA+      +  P++ E  +P +   P+  + +   + ++ ++E
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728

Query: 505 QNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQE 564
           + +   K+  P  +   S   EK++SP     L  K  E  K  ++E   +P  +  ++ 
Sbjct: 729 EAKTPEKAKSPVKEEAKS--PEKAKSPEKAKTLDVKSPE-AKTPAKEEARSPADKFPEKA 785

Query: 565 LEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSK---- 620
               K+EV+            +PE+  SP K    +P +   K+ E KSP+    K    
Sbjct: 786 KSPVKEEVK------------SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833

Query: 621 SLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTS 680
            ++E  KK E  KA  T     + +       ++E    ++  K    +    ++ V+  
Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893

Query: 681 KDKTESVTSGPMSPEGSPSKSPSKKKKK 708
           K++ E     P   + +P+K   K+  K
Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAK 921



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 78/334 (23%), Positives = 137/334 (41%), Gaps = 37/334 (11%)

Query: 412 DGAP-VPALRQHAQKQQKEKTRWLN------------TPNTYLRVNVADEVQRSMGSPRP 458
           +G P +P++  H + + +EK + +             T  T +   V +E ++       
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEG 483

Query: 459 KTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQ 518
           K    +  E E++  G     E   +  P         E ++ ++E+ +   ++  P+ +
Sbjct: 484 KEE--EGGEEEEAEGG-----EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536

Query: 519 LLASVIA----EKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVER 574
              S       EK++SP+ E    +K   + K   +E   +P    + ++ +   KE  +
Sbjct: 537 EAKSPAEVKSPEKAKSPAKEE---AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593

Query: 575 KKLELDG-EKETAP--EEPGSPAKSAPASPVQSPAKE-AETKSPLVSPSKSLEEGTKKTE 630
              E    EK  +P  EE  SPA++   SPV+  AK  AE KSP  + S + EE  K  E
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAK--SPVKEEAKSPAEVKSPEKAKSPTKEE-AKSPE 650

Query: 631 TSKAATTEPETTQPEGVVVNGREEEQTAEEILS--KGLSQMTTSADTDVDTSKDKTESVT 688
            +K+   E E   PE      + E ++ E+  S  K  ++    A + V       E   
Sbjct: 651 KAKSPEKE-EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK 709

Query: 689 SGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE 722
           S       SP K+ S  K++ +TP   K   K+E
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 78/344 (22%), Positives = 141/344 (40%), Gaps = 30/344 (8%)

Query: 389 QEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADE 448
           +E+ K  +EV+ P    +   EE  +P  A  +  +K++ +    + +P           
Sbjct: 535 KEEAKSPAEVKSPEKAKSPAKEEAKSPPEA--KSPEKEEAKSPAEVKSPE-----KAKSP 587

Query: 449 VQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVL---EMRNKIREQ 505
            +    SP    +  KA    K  +  P   ++P +       P EV    + ++  +E+
Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA--KSPAEVKSPEKAKSPTKEE 645

Query: 506 NRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQEL 565
            +   K+  P+ +   S   EK++SP       +K  E  K   +    +P  +     +
Sbjct: 646 AKSPEKAKSPEKEEAKS--PEKAKSPVKAE---AKSPEKAKSPVKAEAKSP--EKAKSPV 698

Query: 566 EEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASP--VQSPAKEAETKSP--LVSPSKS 621
           +E  K  E+ K  +  E+  +PE+  SP K    +P   +SP KE E KSP    SP K+
Sbjct: 699 KEEAKSPEKAKSPVK-EEAKSPEKAKSPVKEEAKTPEKAKSPVKE-EAKSPEKAKSPEKA 756

Query: 622 LEEGTKKTETSKAATTE---PETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVD 678
                K  E    A  E   P    PE      +EE ++ E+  S  L +   + + ++ 
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP-LKEDAKAPEKEIP 815

Query: 679 TSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE 722
             K++ +S       P+    K P KK ++ + P+  K  +KK+
Sbjct: 816 -KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 63/249 (25%), Positives = 103/249 (41%), Gaps = 26/249 (10%)

Query: 497 EMRNKIREQNRQD---VKSAGPQSQLLASVIAEKSRSPSTESQLMSKG--DEDTKDDSEE 551
           E + K+ E++ ++   V+    ++Q+   V  E+ +    E     +G  +E+ +   EE
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500

Query: 552 TVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEA-- 609
           T   P  +    E +E K  V+ +       K    EE  SPA+       +SPAKE   
Sbjct: 501 TKSPPAEEAASPE-KEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559

Query: 610 ---ETKSPLVSPSKSLEEGTKKTETSKA-----ATTEPETTQPEGVVVNGREEEQTAEEI 661
              E KSP    +KS  E  K  E +K+     A +  E   PE      +EE ++  E 
Sbjct: 560 SPPEAKSPEKEEAKSPAE-VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA 618

Query: 662 LSKGLSQMTTSADT-DVDTSKDKTESVTSGP---MSPEGSPSKSPSKKKKKFRTPSFLKK 717
            S    +  + A+    + +K  T+     P    SPE   +KSP K K   +      +
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA-----E 673

Query: 718 SKKKEKVES 726
           +K  EK +S
Sbjct: 674 AKSPEKAKS 682



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 62/275 (22%), Positives = 103/275 (37%), Gaps = 25/275 (9%)

Query: 391 KTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQ 450
           K+  K E + P    + V EE  +P  A      K    K+    TP      + AD+  
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 782

Query: 451 RSMGSP------------RPKTTWMKADEVE---KSSSGMPIRIENPNQFVPLYTDPQEV 495
               SP             P     KA E E   K     P++ E   Q V +   P++ 
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842

Query: 496 LEMRNKIR---EQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKD-DSEE 551
            E +       E+ +   K   P+ +     + EK + P+ E    SK +   ++ + ++
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK-KEPAVEKPKESKVEAKKEEAEDKK 901

Query: 552 TVPNPFSQLTDQ-ELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAE 610
            VP P  +   + E++E  K  E+ ++      +   +EP  PA+   A+P +   KE +
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEK 961

Query: 611 TKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPE 645
            K P   P        K  E  K  + EP   + E
Sbjct: 962 AKKPEEKPKTE----AKAKEDDKTLSKEPSKPKAE 992



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 57/270 (21%), Positives = 102/270 (37%), Gaps = 50/270 (18%)

Query: 384  RHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRV 443
            + P  ++    + E+     V + V EE+      +++  +K ++EK     TP T  + 
Sbjct: 800  KSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAP--ATPKTEEKK 857

Query: 444  NVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIR 503
            +   E      +P+PK    K   VEK                     P+E      K  
Sbjct: 858  DSKKEEAPKKEAPKPKVEEKKEPAVEK---------------------PKESKVEAKKEE 896

Query: 504  EQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQ 563
             ++++ V +  P+ +  A V  ++   P  ++++  K  +D K   E + P         
Sbjct: 897  AEDKKKVPT--PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKA-KEPSKPAE------- 946

Query: 564  ELEEYKKEVERKKLELDGEKETAPEE-PGSPAKSAPASPVQSPAKEAETKSPLVSPSKSL 622
                 KKE   +K +   EK   PEE P + AK          AKE + K+    PSK  
Sbjct: 947  -----KKEAAPEKKDTKEEKAKKPEEKPKTEAK----------AKE-DDKTLSKEPSKPK 990

Query: 623  EEGTKKTETSKAATTEPETTQPEGVVVNGR 652
             E  +K+ ++    ++P     E     G+
Sbjct: 991  AEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 58/269 (21%), Positives = 104/269 (38%), Gaps = 20/269 (7%)

Query: 448 EVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIR-EQN 506
           E QR  G        +K ++ EK  + +  + E   +     ++P+E  E  + +  E+ 
Sbjct: 97  ESQREAGGKEDAEAELKKEDGEKEETTVGSQ-EMTGRKEETKSEPKEAEEKESTLASEKQ 155

Query: 507 RQDVKSAGPQSQLLASVIAEKSRSP--STESQLMSKGDEDTKDDSEETVPNPFSQLTDQE 564
           + + K A P+S   A         P  + E +      ++     +E    P  + TD+E
Sbjct: 156 KAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEE 215

Query: 565 LEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEE 624
            +      E +K  ++ E +  P+EP    ++   +  ++ AKE          ++  E 
Sbjct: 216 AK-----AESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEE------AEDAEEAEP 264

Query: 625 GTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKT 684
           G+   E  +    EPE     G  V     E+  E    +G +  T     D   S   +
Sbjct: 265 GSPSEEQEQDVEKEPE----GGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTS 320

Query: 685 ESVT-SGPMSPEGSPSKSPSKKKKKFRTP 712
            S + S P     SP +SPS  +KK + P
Sbjct: 321 PSASESSPSDVPQSPPESPSSGEKKEKAP 349


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 77/351 (21%), Positives = 120/351 (34%), Gaps = 27/351 (7%)

Query: 389  QEKTKHKSEVEIPATVTA---FVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNV 445
            +E+T ++   + PA  T        E   P PA       +  E   W    NT L    
Sbjct: 826  RERTANEKTTQFPAEPTENRESTANEKTTPFPA-------EPTENREWTANENTTLSPAE 878

Query: 446  ADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQ 505
              E +        KTT   A+  E      P   E         T+  E   + N+I   
Sbjct: 879  PTEHEEMTPLANEKTTLSPAEPTENGER-TPFTNEKTTPSSAEPTEHGERTPLANEITTP 937

Query: 506  NRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQEL 565
            +R +    G +   +A+  A  S +  TE    +  ++ T   +E T     + L ++  
Sbjct: 938  SRAEPTEHGER---IANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENT 994

Query: 566  E----EYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAE--------TKS 613
                 E  +  ER   E        P E G    SA    + SPAK  E         ++
Sbjct: 995  TTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANEN 1054

Query: 614  PLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSA 673
               SP K  E G K T  ++  T  PE     G       E+ T          + TTS 
Sbjct: 1055 TTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSP 1114

Query: 674  DTDVDTS-KDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 723
            +  + +S  + TE       +   +P+ +   K  K  T +  K ++  EK
Sbjct: 1115 NDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEK 1165



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 44/202 (21%), Positives = 76/202 (37%), Gaps = 30/202 (14%)

Query: 526 EKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKET 585
           +K+ S S ES   ++  E T   +E T P+P                     E    +E 
Sbjct: 411 DKTTSSSAES---TEHGERTPLANENTTPSP--------------------AEPTENRER 447

Query: 586 APEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEE-GTKKTETSKAATTEPETTQP 644
              E  +P+ + P    ++ A E  T SP V P+++ E    +KT  S A  TE     P
Sbjct: 448 TANENTTPSPAGPTENRETTANEKTTLSP-VEPTENRETTANEKTTPSPAEPTENGQRTP 506

Query: 645 ---EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKS 701
              E    +  E  +  E       +   + A+   +  +   E  T  P  P  +  ++
Sbjct: 507 FANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRT 566

Query: 702 PSKKKKKFRTPSFLKKSKKKEK 723
           P   +K   TPS  + ++  ++
Sbjct: 567 PLANEK--TTPSLAEPTENGQR 586



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 46/207 (22%), Positives = 81/207 (39%), Gaps = 21/207 (10%)

Query: 520  LASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKE-VERKKLE 578
            LA       R+ S   ++ S   E T+     T  N  +    + ++  K+  +  +K+ 
Sbjct: 1101 LAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMT 1160

Query: 579  LDGEKETA-PEEPGSPAKSAPASPVQSPAKEAET------KSPLVS-PSKSLEEGTKKTE 630
               EK T  PE+  S  +    +P +      +T       +P+   P+++L   T  TE
Sbjct: 1161 QVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTE 1220

Query: 631  TSKA---ATTEPETT-------QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTS 680
            T KA   +T  PE T       +P   V   +    T+  +    ++    +    + TS
Sbjct: 1221 TIKAPVKSTENPEKTAAVTKTIKPSVKVTGDKSLTTTSSHLNKTEVTHQVPTGSFTLITS 1280

Query: 681  KDKTESVTSGPMSPEGSP--SKSPSKK 705
            + K  S+TS     E  P  +K  S+K
Sbjct: 1281 RTKLSSITSEATGNESHPYLNKDGSQK 1307


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 24/172 (13%)

Query: 556 PFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPG-SPAKSAPASPVQSPAKEAETKSP 614
           P+  L D+E EE  ++    + E  GE   APE  G SP    P S   +P ++ E K  
Sbjct: 113 PWPSLLDKEREESLRQKRLSERERIGELG-APEVWGLSPKNPEPDSDEHTPVEDEEPKKS 171

Query: 615 LVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSAD 674
             S S S EE  KK+  SK                  R +++  ++   +   + +  +D
Sbjct: 172 TTSASTSEEEKKKKSSRSKE-----------------RSKKRRKKKSSKRKHKKYSEDSD 214

Query: 675 TDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
           +D D+  D     +S   +   +      +KKKK R+  + KK  KK + ES
Sbjct: 215 SDSDSETD-----SSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 73/323 (22%), Positives = 122/323 (37%), Gaps = 47/323 (14%)

Query: 389  QEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYL-RVNVAD 447
            +E  K   E ++P  V      E+  P     +H Q  Q+EK     T      +  V +
Sbjct: 9610 EEPKKPVPEKKVPPKVIKM---EEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPE 9666

Query: 448  EVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNR 507
            E +R++  P  K   +K           P R E P         P +V E R ++ ++ +
Sbjct: 9667 EPKRAV--PEEKVLKLK-----------PKREEEP---------PAKVTEFRKRVVKEEK 9704

Query: 508  QDVKSAGPQSQLL--ASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQEL 565
              +++   + Q +   +++ EK R+ + E + +S   E+  ++ EE     F +    E 
Sbjct: 9705 VSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEE 9764

Query: 566  EEYKKEVERKKLELDGEKE---TAPEEPGSPAKSAPASPVQS-----PAK-----EAETK 612
             +  +E E ++ E   E E   T PE+P  P K  P  PV +     PAK       E K
Sbjct: 9765 YDQYEEYEEREYERYEEHEEYITEPEKP-IPVKPVPEEPVPTKPKAPPAKVLKKAVPEEK 9823

Query: 613  SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 672
             P+  P K      K  E  K    E        + +  RE+EQ  E      +      
Sbjct: 9824 VPVPIPKKLKPPPPKVPEEPKKVFEEKIR-----ISITKREKEQVTEPAAKVPMKPKRVV 9878

Query: 673  ADTDVDTSKDKTESVTSGPMSPE 695
            A+  V   + +       P  P+
Sbjct: 9879 AEEKVPVPRKEVAPPVRVPEVPK 9901



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 82/352 (23%), Positives = 126/352 (35%), Gaps = 51/352 (14%)

Query: 411   EDGAPVPALRQHAQKQQKEKTRW------LNTPNTYLRVN-VADEVQRSMGSPRPKTTWM 463
             E+  P     Q+ + +++E  R+      +  P   + V  V +E   +     P     
Sbjct: 9757  EEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLK 9816

Query: 464   KADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLAS- 522
             KA   EK    +P +++ P   VP   +P++V E + +I    R+  +   P +++    
Sbjct: 9817  KAVPEEKVPVPIPKKLKPPPPKVP--EEPKKVFEEKIRISITKREKEQVTEPAAKVPMKP 9874

Query: 523   --VIAE-------KSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVE 573
               V+AE       K  +P      + K  E  +   EE V     +   +E EEY  E E
Sbjct: 9875  KRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEE 9934

Query: 574   RKKLELDGEKETAP-------EEPGSPA------------KSAPASPVQSPAKEAETKSP 614
                 E   E+E  P       E P  P             K AP + V    K+ E K P
Sbjct: 9935  ----EFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVP 9990

Query: 615   LVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGL--SQMTTS 672
             ++ P K      K  E  K     PE   P  V            E+  K +   ++   
Sbjct: 9991  VLIPKKEKPPPAKVPEVPKKPV--PEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVP 10048

Query: 673   ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKV 724
             A   V+    K   V    + PE    K P+   KK   P   K  KK+E V
Sbjct: 10049 APKKVEAPPAKVPEVPK-KLIPE---EKKPTPVPKKVEAPP-PKVPKKREPV 10095



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 42/148 (28%), Positives = 55/148 (37%), Gaps = 23/148 (15%)

Query: 580   DGEKETAPEE--PGSPAKSAPASPVQSPA--KEA--ETKSPLVSPSKSLEEGTKKTETSK 633
             +  KE  PE+  P +P K    +PV+ P   KE   E K P+  P K     TK  E  K
Sbjct: 10583 EAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPK 10642

Query: 634   AATTE----------PETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDK 683
              A  E          PE+  PE   V    EE   EE  ++ + +   +A   V     K
Sbjct: 10643 VAVPEKKVPEAIPPKPESPPPE---VFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKK 10699

Query: 684   TESVTSGP----MSPEGSPSKSPSKKKK 707
                    P      PE  P K P   K+
Sbjct: 10700 PVPEKKAPAVVAKKPELPPVKVPEVPKE 10727



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 53/250 (21%), Positives = 92/250 (36%), Gaps = 44/250 (17%)

Query: 469   EKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKS 528
             EK  + +P ++E P   VP   +P  V                 A PQ +    V+ E+ 
Sbjct: 10071 EKKPTPVPKKVEAPPPKVPKKREPVPV---------------PVALPQEE---EVLFEEE 10112

Query: 529   RSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPE 588
               P  E   +   +E+   + EE +P     L ++E      E+  ++ E+  E+E  PE
Sbjct: 10113 IVPEEE---VLPEEEEVLPEEEEVLPEEEEVLPEEE------EIPPEEEEVPPEEEYVPE 10163

Query: 589   EPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVV 648
             E           P +    E + K P+ +P   + E  KK    K    + E   P  V 
Sbjct: 10164 EE-------EFVPEEEVLPEVKPKVPVPAP---VPEIKKKVTEKKVVIPKKEEAPPAKV- 10212

Query: 649   VNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKK 708
                    +  +++  K +          V+ +++  E   S    PE  PS    ++   
Sbjct: 10213 ------PEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAP 10266

Query: 709   FRTPSFLKKS 718
              R P  +KK+
Sbjct: 10267 PRVPEVIKKA 10276



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 44/215 (20%), Positives = 83/215 (38%), Gaps = 22/215 (10%)

Query: 449  VQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQ 508
            + + +  P PK   +    V +    +P+  + P         P +V E+  K   + + 
Sbjct: 9305 IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEP-------AAPPKVPEVPKKPVPEEKI 9357

Query: 509  DVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEY 568
             V  A  +        A  ++ P  +  ++++         EE+ P    ++  +++ E 
Sbjct: 9358 PVPVAKKKE-------APPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEE 9410

Query: 569  KKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSP---AKEAETKSPLVSPSKSLEEG 625
            +K V RK+ E+       P+ P  P K  P   V  P   AK+A      VS  K++ E 
Sbjct: 9411 RKPVPRKEEEV----PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVS-KKTVVEE 9465

Query: 626  TKKTETSKAATTEPETTQPEGVVVNGREEEQTAEE 660
             +     K +   P+  +     V+  EE   +EE
Sbjct: 9466 KRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEE 9500



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 62/267 (23%), Positives = 106/267 (39%), Gaps = 37/267 (13%)

Query: 454   GSPRPKTTWMKADEVEKSSSGMPIRIENPNQF-----VPLYTDPQEVLEMRNKIREQNRQ 508
             G P PK TW K +   +   G+ I+  + + F     V  Y   + +L + N   ++   
Sbjct: 19719 GRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYT 19778

Query: 509   DV----KSAGPQSQLLASVIAEKSRSPSTESQLMSKGD---------EDTKDDSEETVPN 555
              V     + GP   +    I++ S   + E  ++  G           D +  S  TV  
Sbjct: 19779 IVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTT 19838

Query: 556   PFSQLTDQ--ELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKS 613
               S+ + +   LEE K    R    +  E E    +PG    +  AS    P  + + +S
Sbjct: 19839 ECSKTSFRVANLEEGKSYFFR----VFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 19894

Query: 614   PLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSA 673
               VS S S   G KK  +          ++  G VV+   EE   + ++ K LS   ++ 
Sbjct: 19895 --VSKS-SCSIGWKKPHSDGG-------SRIIGYVVDFLTEENKWQRVM-KSLSLQYSA- 19942

Query: 674   DTDVDTSKDKTESVTSGPMSPEGSPSK 700
               D+   K+ T  V++   + EG+PS+
Sbjct: 19943 -KDLTEGKEYTFRVSAENENGEGTPSE 19968



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 8/71 (11%)

Query: 583   KETAPEE--PGSPAKSAPASPVQSPA--KEA--ETKSPLVSPSKSLEEGTKKTETSKAAT 636
             KE  PE+  P  PAK   A P + P   KE   E K P+  P K     TK  E  KAA 
Sbjct: 10502 KEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAV 10561

Query: 637   TEPETTQPEGV 647
               PE   PE +
Sbjct: 10562 --PEKKVPEAI 10570



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 64/305 (20%), Positives = 114/305 (37%), Gaps = 27/305 (8%)

Query: 392   TKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQR 451
             TK+KS  EI +   +    ++G     +     KQ+ E T       T  +  V ++   
Sbjct: 32612 TKYKSTFEISSVQAS----DEGNYSVVVENSEGKQEAEFTL------TIQKARVTEKAVT 32661

Query: 452   S---MGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQ 508
             S   + SP P+   +K+ E  KS    P R+++P    P    P E    +    E+ + 
Sbjct: 32662 SPPRVKSPEPR---VKSPEAVKS----PKRVKSPEPSHPKAVSPTET---KPTPTEKVQH 32711

Query: 509   DVKSAGPQSQLLASVIAEKSRSPST---ESQLMSKGDEDTKDDSEETVPNPFSQLTDQEL 565
                SA P+        A K  +  T   ES ++   +     D ++   N   Q      
Sbjct: 32712 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771

Query: 566   EEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEG 625
               Y+ ++        GE        G  +K+      Q+     E  S +    KS ++ 
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831

Query: 626   TKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTE 685
             T+ T T K     PE    + V+V G ++   + + ++K   + T         +KD  +
Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GK 32890

Query: 686   SVTSG 690
             ++T G
Sbjct: 32891 AITQG 32895



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 12/108 (11%)

Query: 550   EETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSP---- 605
             E   P  F +  +  LEE   EV  +       + T P +   P K APA   + P    
Sbjct: 10659 ESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPP 10718

Query: 606   ------AKEA--ETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPE 645
                    KE   E K PLV P K      K  E  K    E +   P+
Sbjct: 10719 VKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPK 10766



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 67/319 (21%), Positives = 109/319 (34%), Gaps = 31/319 (9%)

Query: 415   PVPALRQHAQKQQKEKTRWLNTPNTYLRV----NVADEVQRSMGSPRPKTTWMKADEVEK 470
             PVP  +  A   +K +   +  P     V     V   V +   +P  K   +  + V +
Sbjct: 10700 PVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPE 10759

Query: 471   SSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRS 530
                 +P + E P   VP     + VLE +  +    R +  S  P+       IA +   
Sbjct: 10760 KKVAVPKKPEVPPAKVP-EVPKKPVLEEKPAVPVPERAE--SPPPEVYEEPEEIAPEEEI 10816

Query: 531   PSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEP 590
                E + +   +E+     E  VP P      +++   KK    KK E    KE  PE+ 
Sbjct: 10817 APEEEKPVPVAEEE-----EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV 10871

Query: 591   GSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGV--- 647
                 K  P  P   PA   E     +   K++    KK    K    E     P  V   
Sbjct: 10872 IEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAI---PKKKVPEKPQVPEKVELTPLKVPGG 10928

Query: 648   ------VVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKS 701
                   ++  R+ E   E +L   L +     +  V+  K +     + P  P       
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP------- 10981

Query: 702   PSKKKKKFRTPSFLKKSKK 720
             P K  ++   P+  K+ +K
Sbjct: 10982 PPKPVEEVEVPTVTKRERK 11000


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 68/315 (21%), Positives = 119/315 (37%), Gaps = 46/315 (14%)

Query: 446 ADEVQRSMGSPRPKTTWMKADEVEKS---SSGMPIRIENPNQFVPLYTDPQEVLEMRNKI 502
           +D+ +    +  PK T  K   V K+   ++  P R  + ++      + ++   M+NK 
Sbjct: 227 SDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286

Query: 503 REQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDS----EETVPNPFS 558
              +     SA P  + L +   +K+     E Q   +  ED+ D+S    EE    P  
Sbjct: 287 GPYSSVPPPSAPPPKKSLGTQPPKKA----VEKQQPVESSEDSSDESDSSSEEEKKPPTK 342

Query: 559 QLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSP 618
            +  +   +     +  +   D     + E+  +P+K A  +   S      TKSP V P
Sbjct: 343 AVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKP 402

Query: 619 --------------------SKSLEEGTKKTETSKA----ATTEPETTQPEGVVVNGREE 654
                               S S EE +  +E  K     ATT+P+ T    + +  ++ 
Sbjct: 403 AAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQA 462

Query: 655 EQTAEEILSKGLSQMTTSADTDVDTSKD----KTESVTSGPMSPEGSPSKSPSKKKKKFR 710
            Q + +  S   S  ++S + +  TSK     K + V  G      +PSK  S KK K  
Sbjct: 463 PQGSRD--SSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG-----AAPSKPASAKKGKAE 515

Query: 711 TPSFLKKSKKKEKVE 725
           + +        E+ E
Sbjct: 516 SSNSSSSDDSSEEEE 530



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 52/212 (24%), Positives = 84/212 (39%), Gaps = 20/212 (9%)

Query: 527 KSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETA 586
           K+ + ++ES    +  +D  DD E+    P  +    + +  K   ++ K        ++
Sbjct: 118 KAAAKASESSSSEESSDD--DDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSS 175

Query: 587 PEEPGSPAK------------SAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKA 634
            +EP    K             AP  P ++  K A  K+   S S S    +  +E  KA
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKA 235

Query: 635 ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP 694
           A T P+ T P+  VV  +   + A     K  S   +S+D + +  K        GP S 
Sbjct: 236 AAT-PKKTVPKKQVV-AKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNK--PGPYSS 291

Query: 695 EGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
              PS  P KK    + P   K  +K++ VES
Sbjct: 292 VPPPSAPPPKKSLGTQPPK--KAVEKQQPVES 321



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 43/176 (24%), Positives = 70/176 (39%), Gaps = 24/176 (13%)

Query: 570 KEVERKKLELDGEKETAPEEP--GSPAKSA--PAS-----PVQSPAKEAETKSPLVSPSK 620
           K+ ++K    D E  +  EE   G PAK A  PA      P ++ AK +E+ S   S   
Sbjct: 76  KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDD 135

Query: 621 SLEEGTKKTETSKAATTEPETTQ--PEGVVVNGREEEQTAEEILSKG----LSQMTTSAD 674
             EE  KK    K    + +  +  P+    +  + + ++E+   K     ++ +T  A 
Sbjct: 136 DDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQ 195

Query: 675 TDVD------TSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKV 724
           T           K       S   S   S S   S+++K   TP   KK+  K++V
Sbjct: 196 TKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP---KKTVPKKQV 248


>gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens]
          Length = 563

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 70/288 (24%), Positives = 111/288 (38%), Gaps = 31/288 (10%)

Query: 464 KADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSA-----GPQSQ 518
           K  ++EK   GM +++++ +  +P   + Q  +   +  + Q  Q  KS      G +SQ
Sbjct: 279 KGTDLEKDKIGMEVKVDS-DAGIPKRQETQLKISEMSIPQGQGAQIKKSVSDVPRGQESQ 337

Query: 519 LLASV--IAEKSRSPSTESQLMS-KGDEDTKDDSEETVPN-PFSQLTD--------QELE 566
           +  S   + +   +  T+S L+  KG E   + SE  VP    SQ+          QE +
Sbjct: 338 VKKSESGVPKGQEAQVTKSGLVVLKGQEAQVEKSEMGVPRRQESQVKKSQSGVSKGQEAQ 397

Query: 567 EYKKE-VERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEG 625
             K+E V  K  E   EK       G   +           +E + K       K  E  
Sbjct: 398 VKKRESVVLKGQEAQVEKSELKVPKGQEGQVEKTEADVPKEQEVQEKKSEAGVLKGPESQ 457

Query: 626 TKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK---- 681
            K TE S   T E +  + E  V+ G+E ++  E    KG +      D + D +K    
Sbjct: 458 VKNTEVSVPETLESQVKKSESGVLKGQEAQEKKESFEDKGNNDKEKERDAEKDPNKKEKG 517

Query: 682 ------DKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEK 723
                 DK +    G    E +  KS   K+ K  T    K +KK E+
Sbjct: 518 DKNTKGDKGKDKVKGKRESEINGEKSKGSKRAKANTGR--KYNKKVEE 563


>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
          Length = 437

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 13/129 (10%)

Query: 588 EEPGSPAKS--APASPVQSPAKE-AETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQP 644
           + PG   KS   P +P  SP+K  AE ++P  +P+KS  E   + ++S  +  E +T + 
Sbjct: 48  QRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQK- 106

Query: 645 EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSK 704
            G       E QT ++  SK   ++ T  D+   T K   E+ T     PE SP++S ++
Sbjct: 107 -GSTSKSGSEAQTTKDSTSKSHPELQTPKDS---TGKSGAEAQT-----PEDSPNRSGAE 157

Query: 705 KKKKFRTPS 713
            K +  +PS
Sbjct: 158 AKTQKDSPS 166



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 47/207 (22%), Positives = 83/207 (40%), Gaps = 19/207 (9%)

Query: 530 SPSTES-QLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPE 588
           SPS  S +  +  D   K  +E       S  +  E +  K    +   E    K+    
Sbjct: 66  SPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKD---- 121

Query: 589 EPGSPAKSAPA--SPVQSPAKE-AETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPE 645
              S +KS P   +P  S  K  AE ++P  SP++S  E   + ++   + +E +TT  +
Sbjct: 122 ---STSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTT--K 176

Query: 646 GVVVNGREEEQTAEEILSKGLSQMTTSAD------TDVDTSKDKTESVTSGPMSPEGSPS 699
            V      + QT ++  SK  ++  T  D       +  T KD +    +    P   PS
Sbjct: 177 DVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPS 236

Query: 700 KSPSKKKKKFRTPSFLKKSKKKEKVES 726
           KS ++++    +P+ +   +   K  S
Sbjct: 237 KSGAEEQTSKDSPNKVVPEQPSRKDHS 263



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 614 PLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSA 673
           PL++     +E      ++   +T P  +Q  G       E QT ++  SK  ++  T  
Sbjct: 19  PLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPE 78

Query: 674 DT------DVDTSKDKTESVTSGPMSPEGSPSKSPSK 704
           DT      +  T KD +    +   + +GS SKS S+
Sbjct: 79  DTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSE 115


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 60/281 (21%), Positives = 104/281 (37%), Gaps = 22/281 (7%)

Query: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDV----- 510
           P P T    A    K ++  P  ++ P    P    P+E+     K       D      
Sbjct: 631 PAPTTPKEPAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688

Query: 511 -KSAGPQSQLLASVIAEKSRSPST-ESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEY 568
            K   P +    +    K  +P+T E+   +  +  T   ++E  P    +  D+   E 
Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDESTPEL 746

Query: 569 KKEVERKKLELDGEKETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEG 625
             E   K LE       +P+EPG P    PA+    + + AK+  T+  L +  ++    
Sbjct: 747 SAEPTPKALE------NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 800

Query: 626 TKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTE 685
            K T+  + ATT  +TT+ +      +    T ++     ++ + T+      T+  KT 
Sbjct: 801 PKMTK--ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTI 858

Query: 686 SVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
           + T     PE +          K  TP   K +K  +K  S
Sbjct: 859 TTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 899



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 55/251 (21%), Positives = 91/251 (36%), Gaps = 20/251 (7%)

Query: 455 SPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQ---DVK 511
           SP   T  + A+   K+    P     P    P  T P+     ++K  E++ +   +  
Sbjct: 738 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 797

Query: 512 SAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKE 571
           +A P+     +   EK+    TES++ +   + T   +++T P   + L    L    K 
Sbjct: 798 TAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KV 851

Query: 572 VERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTET 631
              KK     E    PEE   P   A  S   +P  +  TK+P    S      TKK +T
Sbjct: 852 TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKT 905

Query: 632 SKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGP 691
                    T  P  +     E   T+   +++ + Q TT  +    T   K   V    
Sbjct: 906 MPRVRKPKTTPTPRKMTSTMPELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKS 960

Query: 692 MSPEGSPSKSP 702
               G+  ++P
Sbjct: 961 EDAGGAEGETP 971



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 56/261 (21%), Positives = 90/261 (34%), Gaps = 31/261 (11%)

Query: 458 PKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQS 517
           P T+  + ++V  S      +  NP   +P  +D  +  E    + ++   + K     +
Sbjct: 102 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTN 159

Query: 518 QLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETV-PNPFSQLTDQELEEYKKEVERKK 576
           +  ++   EK+ S      +     +D    S+    P P            K E   K 
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP------------KAETTTKG 207

Query: 577 LELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAAT 636
             L   KE  P  P  PA + P  P  +  K A T     +P+ +    T   E +   T
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 267

Query: 637 TEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEG 696
            EP  T P          ++ A     +     T SA T   T K   E   + P  P  
Sbjct: 268 KEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK---EPAPTTPKKPAP 311

Query: 697 SPSKSPSKKKKKFRTPSFLKK 717
           +  K P+    K  TP+  K+
Sbjct: 312 TTPKEPAPTTPKEPTPTTPKE 332



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 66/308 (21%), Positives = 98/308 (31%), Gaps = 27/308 (8%)

Query: 428 KEKTRWLNTPNTYLRVNVADEVQRS--MGSPRPKT-TWMKADEVEKSSSGMPIRIENPNQ 484
           KEKT       +  + +  D    S  +  P PK  T  K   +       P   + P  
Sbjct: 167 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 226

Query: 485 FVPLYTDPQEVLEMRNKIREQNRQDVKSA-------GPQSQLLASVIAEKSRSPSTESQ- 536
             P    P  +       +E      KSA        P +    +    K  +P+T  + 
Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 286

Query: 537 --LMSKGDEDTKDDSEETVPNPFSQLTDQE---LEEYKKEVERKKLELDGEKETAPEEPG 591
               +K    T  +   T P   +  T +E       +      K      KE AP  P 
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346

Query: 592 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPETTQPEGVVV 649
            PA +AP  P  +  KE    +P      + +E +  T    A TT     TT  E    
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406

Query: 650 NGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKF 709
             +    T +E         TT+ +    T K   E   + P  P  +  K P+    K 
Sbjct: 407 TTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKE 457

Query: 710 RTPSFLKK 717
             P+  KK
Sbjct: 458 PAPTTTKK 465



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 51/235 (21%), Positives = 78/235 (33%), Gaps = 26/235 (11%)

Query: 487 PLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED-- 544
           P  T P+E      K  E      K   P +    +    K  +P+T  +L     E   
Sbjct: 442 PAPTTPKEPAPTTPK--EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 499

Query: 545 --TKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV 602
             T +    T P   +  T +E      E           K  AP  P  PA + P  P 
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPA 555

Query: 603 QSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEIL 662
            +  KE    +P    + +  +GT  T   + A T P+   P+ +     +E        
Sbjct: 556 PTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-------- 606

Query: 663 SKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
                  +T+ D    T+   T   T  P  P  +  K P+    K   P+ LK+
Sbjct: 607 -----PTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 654



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 13/140 (9%)

Query: 581 GEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS--- 632
           G   T P+EP       PA + P     +  KE    +P     K L   T K  TS   
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 633 -KAATTEPETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESV 687
            K A T P+ T P    E      ++   T  E      S+++T   T   T+  K+   
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 741

Query: 688 TSGPMSPEGSPSKSPSKKKK 707
           ++  +S E +P    +  K+
Sbjct: 742 STPELSAEPTPKALENSPKE 761



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 34/148 (22%), Positives = 56/148 (37%), Gaps = 7/148 (4%)

Query: 583 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 642
           K T P+   +       SP  + AK    +  L   S + +E +          T+  TT
Sbjct: 98  KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 157

Query: 643 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK--DKTESVTSG-----PMSPE 695
             +    +G+E+  +A+E  S   +     A T    +K   K E+ T G     P  P 
Sbjct: 158 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 217

Query: 696 GSPSKSPSKKKKKFRTPSFLKKSKKKEK 723
            +  K P+    K  TP+ +K +    K
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPK 245



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 53/276 (19%), Positives = 88/276 (31%), Gaps = 22/276 (7%)

Query: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNK-----IREQNRQDV 510
           P P TT   A    KS+   P          P  T P+E      K       ++     
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337

Query: 511 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 566
           K   P +    +  A K  +P+T  +      ++    T  +   T P   +  T +   
Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397

Query: 567 EYKKEVERKKLELDGEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKS 621
              KE      +      T P+EP       PA + P  P  +  K+    +P   P+ +
Sbjct: 398 TTTKEPAPTTTK---SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 453

Query: 622 LEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK 681
             +    T T K A T P+   P       +E   T  + L+    +       +     
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 509

Query: 682 DKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
              E   + P  P  +  + P+    K   P+  K+
Sbjct: 510 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)

Query: 585 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 639
           T P++P       PA + P  P  +  K+    +P   P+ +  + T  T   K   T P
Sbjct: 437 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 495

Query: 640 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 699
           E   P        +   T  E L+    +  T    +         +  + P  P  +  
Sbjct: 496 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551

Query: 700 KSPSKKKKKFRTPSFLKKS 718
           K P+    K   P+  K++
Sbjct: 552 KEPAPTTPKEPAPTTPKET 570


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 60/281 (21%), Positives = 104/281 (37%), Gaps = 22/281 (7%)

Query: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDV----- 510
           P P T    A    K ++  P  ++ P    P    P+E+     K       D      
Sbjct: 672 PAPTTPKEPAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729

Query: 511 -KSAGPQSQLLASVIAEKSRSPST-ESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEY 568
            K   P +    +    K  +P+T E+   +  +  T   ++E  P    +  D+   E 
Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDESTPEL 787

Query: 569 KKEVERKKLELDGEKETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEG 625
             E   K LE       +P+EPG P    PA+    + + AK+  T+  L +  ++    
Sbjct: 788 SAEPTPKALE------NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 841

Query: 626 TKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTE 685
            K T+  + ATT  +TT+ +      +    T ++     ++ + T+      T+  KT 
Sbjct: 842 PKMTK--ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTI 899

Query: 686 SVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
           + T     PE +          K  TP   K +K  +K  S
Sbjct: 900 TTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 940



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 55/251 (21%), Positives = 91/251 (36%), Gaps = 20/251 (7%)

Query: 455  SPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQ---DVK 511
            SP   T  + A+   K+    P     P    P  T P+     ++K  E++ +   +  
Sbjct: 779  SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 838

Query: 512  SAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKE 571
            +A P+     +   EK+    TES++ +   + T   +++T P   + L    L    K 
Sbjct: 839  TAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KV 892

Query: 572  VERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTET 631
               KK     E    PEE   P   A  S   +P  +  TK+P    S      TKK +T
Sbjct: 893  TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKT 946

Query: 632  SKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGP 691
                     T  P  +     E   T+   +++ + Q TT  +    T   K   V    
Sbjct: 947  MPRVRKPKTTPTPRKMTSTMPELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKS 1001

Query: 692  MSPEGSPSKSP 702
                G+  ++P
Sbjct: 1002 EDAGGAEGETP 1012



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 56/261 (21%), Positives = 90/261 (34%), Gaps = 31/261 (11%)

Query: 458 PKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQS 517
           P T+  + ++V  S      +  NP   +P  +D  +  E    + ++   + K     +
Sbjct: 143 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTN 200

Query: 518 QLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETV-PNPFSQLTDQELEEYKKEVERKK 576
           +  ++   EK+ S      +     +D    S+    P P            K E   K 
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP------------KAETTTKG 248

Query: 577 LELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAAT 636
             L   KE  P  P  PA + P  P  +  K A T     +P+ +    T   E +   T
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 308

Query: 637 TEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEG 696
            EP  T P          ++ A     +     T SA T   T K   E   + P  P  
Sbjct: 309 KEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK---EPAPTTPKKPAP 352

Query: 697 SPSKSPSKKKKKFRTPSFLKK 717
           +  K P+    K  TP+  K+
Sbjct: 353 TTPKEPAPTTPKEPTPTTPKE 373



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 66/308 (21%), Positives = 98/308 (31%), Gaps = 27/308 (8%)

Query: 428 KEKTRWLNTPNTYLRVNVADEVQRS--MGSPRPKT-TWMKADEVEKSSSGMPIRIENPNQ 484
           KEKT       +  + +  D    S  +  P PK  T  K   +       P   + P  
Sbjct: 208 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 267

Query: 485 FVPLYTDPQEVLEMRNKIREQNRQDVKSA-------GPQSQLLASVIAEKSRSPSTESQ- 536
             P    P  +       +E      KSA        P +    +    K  +P+T  + 
Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 327

Query: 537 --LMSKGDEDTKDDSEETVPNPFSQLTDQE---LEEYKKEVERKKLELDGEKETAPEEPG 591
               +K    T  +   T P   +  T +E       +      K      KE AP  P 
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387

Query: 592 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPETTQPEGVVV 649
            PA +AP  P  +  KE    +P      + +E +  T    A TT     TT  E    
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447

Query: 650 NGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKF 709
             +    T +E         TT+ +    T K   E   + P  P  +  K P+    K 
Sbjct: 448 TTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKE 498

Query: 710 RTPSFLKK 717
             P+  KK
Sbjct: 499 PAPTTTKK 506



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 51/235 (21%), Positives = 78/235 (33%), Gaps = 26/235 (11%)

Query: 487 PLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED-- 544
           P  T P+E      K  E      K   P +    +    K  +P+T  +L     E   
Sbjct: 483 PAPTTPKEPAPTTPK--EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 540

Query: 545 --TKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV 602
             T +    T P   +  T +E      E           K  AP  P  PA + P  P 
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPA 596

Query: 603 QSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEIL 662
            +  KE    +P    + +  +GT  T   + A T P+   P+ +     +E        
Sbjct: 597 PTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-------- 647

Query: 663 SKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
                  +T+ D    T+   T   T  P  P  +  K P+    K   P+ LK+
Sbjct: 648 -----PTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 695



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 13/140 (9%)

Query: 581 GEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS--- 632
           G   T P+EP       PA + P     +  KE    +P     K L   T K  TS   
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 633 -KAATTEPETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESV 687
            K A T P+ T P    E      ++   T  E      S+++T   T   T+  K+   
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 782

Query: 688 TSGPMSPEGSPSKSPSKKKK 707
           ++  +S E +P    +  K+
Sbjct: 783 STPELSAEPTPKALENSPKE 802



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 34/148 (22%), Positives = 56/148 (37%), Gaps = 7/148 (4%)

Query: 583 KETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETT 642
           K T P+   +       SP  + AK    +  L   S + +E +          T+  TT
Sbjct: 139 KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 198

Query: 643 QPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK--DKTESVTSG-----PMSPE 695
             +    +G+E+  +A+E  S   +     A T    +K   K E+ T G     P  P 
Sbjct: 199 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 258

Query: 696 GSPSKSPSKKKKKFRTPSFLKKSKKKEK 723
            +  K P+    K  TP+ +K +    K
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTTPK 286



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 53/276 (19%), Positives = 88/276 (31%), Gaps = 22/276 (7%)

Query: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNK-----IREQNRQDV 510
           P P TT   A    KS+   P          P  T P+E      K       ++     
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378

Query: 511 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 566
           K   P +    +  A K  +P+T  +      ++    T  +   T P   +  T +   
Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438

Query: 567 EYKKEVERKKLELDGEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKS 621
              KE      +      T P+EP       PA + P  P  +  K+    +P   P+ +
Sbjct: 439 TTTKEPAPTTTK---SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 494

Query: 622 LEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK 681
             +    T T K A T P+   P       +E   T  + L+    +       +     
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 550

Query: 682 DKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
              E   + P  P  +  + P+    K   P+  K+
Sbjct: 551 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)

Query: 585 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 639
           T P++P       PA + P  P  +  K+    +P   P+ +  + T  T   K   T P
Sbjct: 478 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 536

Query: 640 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 699
           E   P        +   T  E L+    +  T    +         +  + P  P  +  
Sbjct: 537 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592

Query: 700 KSPSKKKKKFRTPSFLKKS 718
           K P+    K   P+  K++
Sbjct: 593 KEPAPTTPKEPAPTTPKET 611


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 60/281 (21%), Positives = 104/281 (37%), Gaps = 22/281 (7%)

Query: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDV----- 510
           P P T    A    K ++  P  ++ P    P    P+E+     K       D      
Sbjct: 724 PAPTTPKEPAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781

Query: 511 -KSAGPQSQLLASVIAEKSRSPST-ESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEY 568
            K   P +    +    K  +P+T E+   +  +  T   ++E  P    +  D+   E 
Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDESTPEL 839

Query: 569 KKEVERKKLELDGEKETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEG 625
             E   K LE       +P+EPG P    PA+    + + AK+  T+  L +  ++    
Sbjct: 840 SAEPTPKALE------NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 893

Query: 626 TKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTE 685
            K T+  + ATT  +TT+ +      +    T ++     ++ + T+      T+  KT 
Sbjct: 894 PKMTK--ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTI 951

Query: 686 SVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
           + T     PE +          K  TP   K +K  +K  S
Sbjct: 952 TTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 992



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 68/335 (20%), Positives = 115/335 (34%), Gaps = 38/335 (11%)

Query: 389 QEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADE 448
           QE +   S     +T+      ++ A    L++  + +  +K R    P    +  V DE
Sbjct: 123 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP--KPPVVDE 180

Query: 449 VQRSMGS-----PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIR 503
               + +       P T+  + ++V  S      +  NP   +P  +D  +  E    + 
Sbjct: 181 AGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK--ETSLTVN 238

Query: 504 EQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETV-PNPFSQLTD 562
           ++   + K     ++  ++   EK+ S      +     +D    S+    P P      
Sbjct: 239 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP------ 292

Query: 563 QELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSL 622
                 K E   K   L   KE  P  P  PA + P  P  +  K A T     +P+ + 
Sbjct: 293 ------KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346

Query: 623 EEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKD 682
              T   E +   T EP  T P          ++ A     +     T SA T   T K 
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK- 392

Query: 683 KTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
             E   + P  P  +  K P+    K  TP+  K+
Sbjct: 393 --EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 425



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 55/251 (21%), Positives = 91/251 (36%), Gaps = 20/251 (7%)

Query: 455  SPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQ---DVK 511
            SP   T  + A+   K+    P     P    P  T P+     ++K  E++ +   +  
Sbjct: 831  SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 890

Query: 512  SAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKE 571
            +A P+     +   EK+    TES++ +   + T   +++T P   + L    L    K 
Sbjct: 891  TAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KV 944

Query: 572  VERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTET 631
               KK     E    PEE   P   A  S   +P  +  TK+P    S      TKK +T
Sbjct: 945  TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKT 998

Query: 632  SKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGP 691
                     T  P  +     E   T+   +++ + Q TT  +    T   K   V    
Sbjct: 999  MPRVRKPKTTPTPRKMTSTMPELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKS 1053

Query: 692  MSPEGSPSKSP 702
                G+  ++P
Sbjct: 1054 EDAGGAEGETP 1064



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 66/308 (21%), Positives = 98/308 (31%), Gaps = 27/308 (8%)

Query: 428 KEKTRWLNTPNTYLRVNVADEVQRS--MGSPRPKT-TWMKADEVEKSSSGMPIRIENPNQ 484
           KEKT       +  + +  D    S  +  P PK  T  K   +       P   + P  
Sbjct: 260 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 319

Query: 485 FVPLYTDPQEVLEMRNKIREQNRQDVKSA-------GPQSQLLASVIAEKSRSPSTESQ- 536
             P    P  +       +E      KSA        P +    +    K  +P+T  + 
Sbjct: 320 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 379

Query: 537 --LMSKGDEDTKDDSEETVPNPFSQLTDQE---LEEYKKEVERKKLELDGEKETAPEEPG 591
               +K    T  +   T P   +  T +E       +      K      KE AP  P 
Sbjct: 380 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 439

Query: 592 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPETTQPEGVVV 649
            PA +AP  P  +  KE    +P      + +E +  T    A TT     TT  E    
Sbjct: 440 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 499

Query: 650 NGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKF 709
             +    T +E         TT+ +    T K   E   + P  P  +  K P+    K 
Sbjct: 500 TTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKE 550

Query: 710 RTPSFLKK 717
             P+  KK
Sbjct: 551 PAPTTTKK 558



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 51/235 (21%), Positives = 78/235 (33%), Gaps = 26/235 (11%)

Query: 487 PLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED-- 544
           P  T P+E      K  E      K   P +    +    K  +P+T  +L     E   
Sbjct: 535 PAPTTPKEPAPTTPK--EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 592

Query: 545 --TKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV 602
             T +    T P   +  T +E      E           K  AP  P  PA + P  P 
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPA 648

Query: 603 QSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEIL 662
            +  KE    +P    + +  +GT  T   + A T P+   P+ +     +E        
Sbjct: 649 PTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-------- 699

Query: 663 SKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
                  +T+ D    T+   T   T  P  P  +  K P+    K   P+ LK+
Sbjct: 700 -----PTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 747



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 13/140 (9%)

Query: 581 GEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS--- 632
           G   T P+EP       PA + P     +  KE    +P     K L   T K  TS   
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 633 -KAATTEPETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESV 687
            K A T P+ T P    E      ++   T  E      S+++T   T   T+  K+   
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 834

Query: 688 TSGPMSPEGSPSKSPSKKKK 707
           ++  +S E +P    +  K+
Sbjct: 835 STPELSAEPTPKALENSPKE 854



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 53/276 (19%), Positives = 88/276 (31%), Gaps = 22/276 (7%)

Query: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNK-----IREQNRQDV 510
           P P TT   A    KS+   P          P  T P+E      K       ++     
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 430

Query: 511 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 566
           K   P +    +  A K  +P+T  +      ++    T  +   T P   +  T +   
Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490

Query: 567 EYKKEVERKKLELDGEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKS 621
              KE      +      T P+EP       PA + P  P  +  K+    +P   P+ +
Sbjct: 491 TTTKEPAPTTTK---SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 546

Query: 622 LEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK 681
             +    T T K A T P+   P       +E   T  + L+    +       +     
Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 602

Query: 682 DKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
              E   + P  P  +  + P+    K   P+  K+
Sbjct: 603 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)

Query: 585 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 639
           T P++P       PA + P  P  +  K+    +P   P+ +  + T  T   K   T P
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 588

Query: 640 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 699
           E   P        +   T  E L+    +  T    +         +  + P  P  +  
Sbjct: 589 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644

Query: 700 KSPSKKKKKFRTPSFLKKS 718
           K P+    K   P+  K++
Sbjct: 645 KEPAPTTPKEPAPTTPKET 663


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 60/281 (21%), Positives = 104/281 (37%), Gaps = 22/281 (7%)

Query: 456  PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDV----- 510
            P P T    A    K ++  P  ++ P    P    P+E+     K       D      
Sbjct: 765  PAPTTPKEPAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822

Query: 511  -KSAGPQSQLLASVIAEKSRSPST-ESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEY 568
             K   P +    +    K  +P+T E+   +  +  T   ++E  P    +  D+   E 
Sbjct: 823  PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDESTPEL 880

Query: 569  KKEVERKKLELDGEKETAPEEPGSPAKSAPASP---VQSPAKEAETKSPLVSPSKSLEEG 625
              E   K LE       +P+EPG P    PA+    + + AK+  T+  L +  ++    
Sbjct: 881  SAEPTPKALE------NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 934

Query: 626  TKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTE 685
             K T+  + ATT  +TT+ +      +    T ++     ++ + T+      T+  KT 
Sbjct: 935  PKMTK--ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTI 992

Query: 686  SVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 726
            + T     PE +          K  TP   K +K  +K  S
Sbjct: 993  TTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 1033



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 68/335 (20%), Positives = 115/335 (34%), Gaps = 38/335 (11%)

Query: 389 QEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADE 448
           QE +   S     +T+      ++ A    L++  + +  +K R    P    +  V DE
Sbjct: 164 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP--KPPVVDE 221

Query: 449 VQRSMGS-----PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIR 503
               + +       P T+  + ++V  S      +  NP   +P  +D  +  E    + 
Sbjct: 222 AGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK--ETSLTVN 279

Query: 504 EQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETV-PNPFSQLTD 562
           ++   + K     ++  ++   EK+ S      +     +D    S+    P P      
Sbjct: 280 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP------ 333

Query: 563 QELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSL 622
                 K E   K   L   KE  P  P  PA + P  P  +  K A T     +P+ + 
Sbjct: 334 ------KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387

Query: 623 EEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKD 682
              T   E +   T EP  T P          ++ A     +     T SA T   T K 
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTP----------KEPAPTTTKEPAPTTTKSAPT---TPK- 433

Query: 683 KTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
             E   + P  P  +  K P+    K  TP+  K+
Sbjct: 434 --EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 466



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 55/251 (21%), Positives = 91/251 (36%), Gaps = 20/251 (7%)

Query: 455  SPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQ---DVK 511
            SP   T  + A+   K+    P     P    P  T P+     ++K  E++ +   +  
Sbjct: 872  SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 931

Query: 512  SAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKE 571
            +A P+     +   EK+    TES++ +   + T   +++T P   + L    L    K 
Sbjct: 932  TAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP--KV 985

Query: 572  VERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTET 631
               KK     E    PEE   P   A  S   +P  +  TK+P    S      TKK +T
Sbjct: 986  TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS------TKKPKT 1039

Query: 632  SKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGP 691
                     T  P  +     E   T+   +++ + Q TT  +    T   K   V    
Sbjct: 1040 MPRVRKPKTTPTPRKMTSTMPELNPTSR--IAEAMLQTTTRPN---QTPNSKLVEVNPKS 1094

Query: 692  MSPEGSPSKSP 702
                G+  ++P
Sbjct: 1095 EDAGGAEGETP 1105



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 66/308 (21%), Positives = 98/308 (31%), Gaps = 27/308 (8%)

Query: 428 KEKTRWLNTPNTYLRVNVADEVQRS--MGSPRPKT-TWMKADEVEKSSSGMPIRIENPNQ 484
           KEKT       +  + +  D    S  +  P PK  T  K   +       P   + P  
Sbjct: 301 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 360

Query: 485 FVPLYTDPQEVLEMRNKIREQNRQDVKSA-------GPQSQLLASVIAEKSRSPSTESQ- 536
             P    P  +       +E      KSA        P +    +    K  +P+T  + 
Sbjct: 361 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 420

Query: 537 --LMSKGDEDTKDDSEETVPNPFSQLTDQE---LEEYKKEVERKKLELDGEKETAPEEPG 591
               +K    T  +   T P   +  T +E       +      K      KE AP  P 
Sbjct: 421 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 480

Query: 592 SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATT--EPETTQPEGVVV 649
            PA +AP  P  +  KE    +P      + +E +  T    A TT     TT  E    
Sbjct: 481 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 540

Query: 650 NGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKF 709
             +    T +E         TT+ +    T K   E   + P  P  +  K P+    K 
Sbjct: 541 TTKSAPTTPKE------PSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKE 591

Query: 710 RTPSFLKK 717
             P+  KK
Sbjct: 592 PAPTTTKK 599



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 51/235 (21%), Positives = 78/235 (33%), Gaps = 26/235 (11%)

Query: 487 PLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED-- 544
           P  T P+E      K  E      K   P +    +    K  +P+T  +L     E   
Sbjct: 576 PAPTTPKEPAPTTPK--EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 633

Query: 545 --TKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV 602
             T +    T P   +  T +E      E           K  AP  P  PA + P  P 
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP----KAAAPNTPKEPAPTTPKEPA 689

Query: 603 QSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEIL 662
            +  KE    +P    + +  +GT  T   + A T P+   P+ +     +E        
Sbjct: 690 PTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-------- 740

Query: 663 SKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
                  +T+ D    T+   T   T  P  P  +  K P+    K   P+ LK+
Sbjct: 741 -----PTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAPTTPKGTAPTTLKE 788



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 13/140 (9%)

Query: 581 GEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETS--- 632
           G   T P+EP       PA + P     +  KE    +P     K L   T K  TS   
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 633 -KAATTEPETTQP----EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESV 687
            K A T P+ T P    E      ++   T  E      S+++T   T   T+  K+   
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 875

Query: 688 TSGPMSPEGSPSKSPSKKKK 707
           ++  +S E +P    +  K+
Sbjct: 876 STPELSAEPTPKALENSPKE 895



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 53/276 (19%), Positives = 88/276 (31%), Gaps = 22/276 (7%)

Query: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNK-----IREQNRQDV 510
           P P TT   A    KS+   P          P  T P+E      K       ++     
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 471

Query: 511 KSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED----TKDDSEETVPNPFSQLTDQELE 566
           K   P +    +  A K  +P+T  +      ++    T  +   T P   +  T +   
Sbjct: 472 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531

Query: 567 EYKKEVERKKLELDGEKETAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKS 621
              KE      +      T P+EP       PA + P  P  +  K+    +P   P+ +
Sbjct: 532 TTTKEPAPTTTK---SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 587

Query: 622 LEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSK 681
             +    T T K A T P+   P       +E   T  + L+    +       +     
Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 643

Query: 682 DKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKK 717
              E   + P  P  +  + P+    K   P+  K+
Sbjct: 644 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 28/139 (20%), Positives = 48/139 (34%), Gaps = 10/139 (7%)

Query: 585 TAPEEPG-----SPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEP 639
           T P++P       PA + P  P  +  K+    +P   P+ +  + T  T   K   T P
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP 629

Query: 640 ETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPS 699
           E   P        +   T  E L+    +  T    +         +  + P  P  +  
Sbjct: 630 EKLAP----TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685

Query: 700 KSPSKKKKKFRTPSFLKKS 718
           K P+    K   P+  K++
Sbjct: 686 KEPAPTTPKEPAPTTPKET 704


>gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]
          Length = 490

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 32/223 (14%)

Query: 516 QSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERK 575
           +S  L  V  EKS +    S  +S  DE TK                  L + KKE  RK
Sbjct: 246 ESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSL---------------LNKKKKEARRK 290

Query: 576 KLELDGEKETAPEEPGSPAKSAPA----SPVQSPAKEAETKSPLVSPSKSLEEGTKKTET 631
           + E + EK+   ++    A+   +      V   + +   K P     ++ E G KK   
Sbjct: 291 RRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGR 350

Query: 632 SKA---ATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVT 688
            KA   AT E E   P+ V +  +       EI      + + +   +  T + K     
Sbjct: 351 GKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKAL 410

Query: 689 SGPMSPEG----SPSKSPSKKKK------KFRTPSFLKKSKKK 721
               +P+     +P KSP KK K      K ++PS  KK  ++
Sbjct: 411 PASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQ 453


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 54/235 (22%), Positives = 98/235 (41%), Gaps = 17/235 (7%)

Query: 499 RNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFS 558
           + K+++ +++      P+S    S  A+ +R+ S   +  SK D+  KD  + T    FS
Sbjct: 351 KKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT----FS 406

Query: 559 QLTDQELEEYKKEVERKK----LELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETKSP 614
             ++ ELE  + + + KK     + D +K    +E  + A S P    +   K+ +    
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKK--- 463

Query: 615 LVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSAD 674
                 S ++  KK     A +TE E+           +E++ +++ + K   + T S D
Sbjct: 464 --GKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTD 521

Query: 675 TDVDTSKDKTESVTSGPMSPEGSPSKSPSKK---KKKFRTPSFLKKSKKKEKVES 726
            + D S  KT   TS  +    + S+    K   KKK         + K E +ES
Sbjct: 522 AEFDES-SKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLES 575


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 47/200 (23%), Positives = 75/200 (37%), Gaps = 31/200 (15%)

Query: 526  EKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKET 585
            E+      E +   + +E+   + EE     + +  ++E EE+++E E ++ EL+ E+E 
Sbjct: 889  EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948

Query: 586  APEEP----------------GSPAKSAPASPVQSPAKEAETKSPLVSPSKSLEEG---- 625
              EE                 G   + AP  P   PA       P V P    E G    
Sbjct: 949  EDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLE 1008

Query: 626  --TKKTETSKAATTEPETTQPEGVVVNG---REEEQTA-----EEILSKGLSQMTTSADT 675
                 TE  + A T P T  PE +   G   RE E  A     +E++ +  S   T  + 
Sbjct: 1009 VEEPGTEEERGADTAP-TLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEE 1067

Query: 676  DVDTSKDKTESVTSGPMSPE 695
            + +   DK +     P   E
Sbjct: 1068 ETEDGSDKVQPPPETPAEEE 1087


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 77/327 (23%), Positives = 130/327 (39%), Gaps = 47/327 (14%)

Query: 396 SEVEIPATVTAFVFEEDGA---PVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRS 452
           S  + PA +   + EE  A   P PA   H Q Q   +     TP+      VA+   + 
Sbjct: 261 STEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTE----ETPDAEAATAVAENSVKV 316

Query: 453 MGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKS 512
              P        A+E        P+ +E P +  P   +    +E+  +I   + ++  S
Sbjct: 317 QPPP--------AEEA-------PL-VEFPAEIQPPSAEESPSVELLAEILPPSAEESPS 360

Query: 513 AGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEV 572
             P +++L    AEKS S     ++ S   +       E  P P     +  LEE   +V
Sbjct: 361 EEPPAEILPPP-AEKSPSVELLGEIRSPSAQKAPI---EVQPLP----AEGALEEAPAKV 412

Query: 573 ERKKLE--LDGEKETAPEE-PGSPAKSAPASP-VQSPAKEAETKSPLVSPSKSLEEGTKK 628
           E   +E  L   +   PEE P   A+    S  +++PA+EA T+     P ++  E    
Sbjct: 413 EPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEAS- 471

Query: 629 TETSKAATTEPETTQPEGVVVNGREEEQTAEEI---LSKGLSQMTTSADTD--------V 677
            E    A TEP   +      +   EE +AEE    +   L++ TT+ +          +
Sbjct: 472 AEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAI 531

Query: 678 DTSKDKTESVTSGPMSPEGSPSKSPSK 704
           +   D+T +    P+S E S  ++P++
Sbjct: 532 EAPADETPAEAQSPLSEETSAEEAPAE 558



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 75/344 (21%), Positives = 128/344 (37%), Gaps = 48/344 (13%)

Query: 399 EIPATVTAFVFEEDGAPV-PALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPR 457
           E PA V     EE  A V P L + A +++  + +      T      A+E      SP 
Sbjct: 407 EAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMET-----PAEEAPTEFQSPL 461

Query: 458 PKTTWMK--ADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDV--KSA 513
           PK T  +  + E++  ++  P   E P +     ++     E   +++    ++   + A
Sbjct: 462 PKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEA 521

Query: 514 GPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFS----------QLTDQ 563
             + QLLA++ A    +P+     +S  +E + +++   V +P +          +L   
Sbjct: 522 SAEIQLLAAIEAPADETPAEAQSPLS--EETSAEEAPAEVQSPSAKGVSIEEAPLELQPP 579

Query: 564 ELEEYKKEVERKKLELDGEKETAPEEPGS-----PAKSAPASPVQSPAKEAET------- 611
             EE   E     ++L    E + EE  +     PA+ APA     PA+EA         
Sbjct: 580 SGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPA 639

Query: 612 -KSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEI-LSKGLSQM 669
            ++P        EE   + +   A     E   P         +   AEE  + + L+ +
Sbjct: 640 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAV 699

Query: 670 TTSADTDV---DTSKDK---------TESVTSGPMSPEGSPSKS 701
            +    DV   + S DK         TE    G  S E SP  S
Sbjct: 700 HSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPS 743


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/237 (17%), Positives = 96/237 (40%), Gaps = 6/237 (2%)

Query: 492 PQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEE 551
           P++  E+ N   EQ++ + K +  +S  + S   ++ +      QL+SK    +  +++ 
Sbjct: 24  PEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKR 83

Query: 552 TVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV---QSPAKE 608
            V       T+ + EEY++    K+L+ D +   +      P K+ P       + P + 
Sbjct: 84  IVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERR 143

Query: 609 AETKSPLVSPSKSLE---EGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKG 665
           A++ +P  S    LE     ++ +++SK      E         +G  +EQ       + 
Sbjct: 144 AKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEE 203

Query: 666 LSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE 722
             +     D +V+   ++ E V       E    +   +++++       ++ +K+E
Sbjct: 204 GVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/237 (17%), Positives = 96/237 (40%), Gaps = 6/237 (2%)

Query: 492 PQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEE 551
           P++  E+ N   EQ++ + K +  +S  + S   ++ +      QL+SK    +  +++ 
Sbjct: 24  PEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKR 83

Query: 552 TVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPV---QSPAKE 608
            V       T+ + EEY++    K+L+ D +   +      P K+ P       + P + 
Sbjct: 84  IVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERR 143

Query: 609 AETKSPLVSPSKSLE---EGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKG 665
           A++ +P  S    LE     ++ +++SK      E         +G  +EQ       + 
Sbjct: 144 AKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEE 203

Query: 666 LSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE 722
             +     D +V+   ++ E V       E    +   +++++       ++ +K+E
Sbjct: 204 GVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,878,496
Number of Sequences: 37866
Number of extensions: 1470417
Number of successful extensions: 11819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 765
Number of HSP's that attempted gapping in prelim test: 8788
Number of HSP's gapped (non-prelim): 2887
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.